Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 216.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.5;Exocrine glandular cells: 170.7;NK-cells: 208.1;Syncytiotrophoblasts: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.3" "Lineage enriched" "Detected in many" 5 "T-cells: 160.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 218.4;SK-BR-3: 277.7;SK-MEL-30: 297.8;TIME: 241.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" NA NA 32000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" 50.9 13.2 79.6 12.7 67.7 19.6 50.5 46.9 115.2 36.3 0.0 36.7 26.1 19.7 84.2 46.7 52.2 69.6 36.8 68.7 71.5 158.9 4.2 37.3 5.2 64.6 76.2 5.3 59.8 28.4 17.7 101.3 73.9 31.7 33.4 6.6 92.2 57.5 15.7 87.5 19.3 19.8 54.8 12.3 47.9 45.4 92.5 28.9 216.3 16.9 15.6 37.1 37.8 51.6 41.8 47.1 12.0 0.6 0.0 0.1 127.7 8.5 3.9 14.4 2.6 34.7 218.4 0.2 110.5 8.2 196.1 149.1 0.0 103.4 5.1 1.6 0.0 5.1 56.0 39.3 0.3 0.4 2.1 2.4 143.8 24.5 10.2 15.8 118.1 1.0 0.1 1.2 3.2 51.4 107.3 0.8 1.7 143.3 42.6 3.8 1.4 30.8 209.4 134.9 38.2 1.2 2.0 277.7 297.8 8.4 123.8 0.8 241.4 25.6 38.0 1.5 96.2 0.2 2.1 0.6 200.5 0.7 62.9 2.9 0.8 0.2 160.3 0.5 1.9 0.3 10.5 62.6 0.2 0.1 5.3 45.2 3.3 30.6 0.7 0.3 0.2 37.1 79.6 67.7 46.9 115.2 68.7 71.5 64.6 76.2 73.9 54.8 92.5 51.6 107.7 9.6 11.9 113.9 3.7 0.0 24.1 0.0 11.4 0.9 29.6 27.2 4.3 15.7 21.7 79.1 0.0 222.5 120.4 17.7 27.4 33.9 74.0 24.6 4.3 53.9 20.6 17.7 3.5 170.7 25.1 4.7 29.0 45.2 5.1 88.2 30.0 0.5 22.8 0.0 4.9 23.2 0.0 3.5 0.0 31.3 3.1 6.1 0.0 41.2 1.1 4.8 208.1 85.5 1.3 101.1 12.3 0.0 19.1 15.2 5.6 132.6 16.8 0.5 0.0 1.6 7.1 2.7 0.9 23.0 0.0 186.5 35.1 0.4 24.6 19.5 AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.4;Cardiomyocytes: 39.3;Early spermatids: 105.4;Endothelial cells: 72.0;Extravillous trophoblasts: 47.1;Hepatic stellate cells: 47.2;Late spermatids: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.6;HUVEC TERT2: 20.8;TIME: 33.9;WM-115: 79.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" 23.9 2.8 1.7 2.1 0.9 0.1 15.2 1.1 1.3 4.2 1.0 3.5 0.8 7.1 0.6 4.3 10.1 4.0 26.1 0.9 1.0 4.1 2.1 13.3 2.3 1.4 1.1 3.3 1.0 6.1 2.4 14.4 1.4 3.3 0.7 1.3 3.4 1.9 31.6 6.0 3.4 3.5 1.1 2.9 2.4 2.3 1.8 3.4 7.4 16.6 0.8 4.6 3.7 0.9 7.0 2.4 0.1 0.3 9.9 2.1 42.6 1.5 5.5 5.4 8.9 0.1 4.1 0.0 3.3 2.5 13.7 1.4 0.8 6.2 2.2 0.0 1.0 1.6 0.9 0.0 5.2 0.0 0.1 7.3 1.0 3.0 11.6 4.3 20.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 1.0 0.0 5.4 0.0 0.0 0.0 3.5 1.1 0.7 1.1 4.4 0.1 14.8 1.5 0.2 0.4 33.9 2.5 7.7 0.1 1.2 0.0 0.0 0.0 0.5 0.1 79.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.9 1.1 1.3 0.9 1.0 1.4 1.1 1.4 1.1 1.8 0.9 62.4 0.0 1.3 0.3 0.2 1.5 1.4 4.6 0.0 0.3 0.4 0.5 39.3 1.5 4.1 0.0 0.0 14.2 0.2 0.0 0.0 0.3 105.4 0.3 0.4 72.0 0.0 0.0 2.9 0.0 47.1 4.5 0.0 0.2 1.3 0.0 47.2 0.6 2.7 0.0 1.2 0.0 0.0 4.2 1.3 50.4 9.6 0.7 7.2 10.3 0.0 0.5 0.0 2.0 0.3 0.0 0.0 15.8 0.0 4.0 0.0 0.8 6.4 5.3 13.1 4.6 4.0 0.5 4.8 0.3 1.4 6.4 0.5 1.8 0.0 5.4 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 4 "Adipocytes: 48.0;Collecting duct cells: 49.7;Endothelial cells: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;SCLC-21H: 3.7;U-266/84: 3.7;U-698: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" 5.2 0.2 0.1 0.2 0.0 0.8 3.1 3.9 0.1 1.0 0.5 0.8 0.6 0.9 0.1 0.6 1.6 1.0 5.1 0.1 0.0 8.1 0.0 1.3 1.0 0.3 0.5 0.2 0.6 0.7 0.1 0.2 0.4 0.7 0.2 0.0 0.7 0.6 3.1 1.5 0.8 0.8 0.1 0.3 0.7 0.2 0.1 0.4 0.9 4.0 0.3 0.8 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.1 1.2 0.6 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.8 1.0 0.1 0.0 0.0 1.4 0.6 1.4 0.0 0.0 3.7 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.6 3.7 3.6 0.0 0.9 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.1 0.0 0.3 0.5 0.4 0.1 0.1 0.2 48.0 3.2 1.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 49.7 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.6 0.8 0.0 0.0 0.1 1.3 0.0 0.1 0.5 0.0 0.1 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 23.0;Hepatic stellate cells: 16.8;Inhibitory neurons: 22.8;Microglial cells: 74.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "EFO-21: 37.0;HUVEC TERT2: 149.6;Karpas-707: 81.6;SiHa: 70.0;TIME: 74.3;U-266/84: 41.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" No No 4970000 46000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" 16.5 3.1 5.1 2.2 5.9 0.4 12.7 3.9 6.2 3.2 7.8 3.7 3.0 3.5 0.6 2.0 2.4 2.1 5.1 3.9 3.7 17.8 1.9 9.1 1.5 4.9 4.5 8.2 0.6 0.6 4.6 18.1 4.7 2.8 2.7 0.1 2.3 2.6 3.1 3.5 3.0 2.3 4.8 4.6 4.7 2.2 5.7 0.9 1.5 1.3 2.4 3.3 3.0 4.1 0.9 2.4 0.3 0.0 0.4 0.3 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 37.0 1.1 1.6 0.5 1.1 0.2 0.0 0.0 5.7 15.9 21.8 1.4 0.8 1.1 16.7 0.0 0.0 0.7 2.4 9.6 149.6 0.0 0.0 81.6 0.0 0.3 0.0 0.0 0.8 0.5 12.0 0.6 0.0 15.3 0.5 0.0 12.3 0.0 70.0 0.0 0.0 9.3 0.0 0.0 74.3 0.0 4.7 0.5 2.6 11.3 41.3 0.1 2.3 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 5.1 5.9 3.9 6.2 3.9 3.7 4.9 4.5 4.7 4.8 5.7 4.1 23.0 0.0 0.5 1.6 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3.5 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.8 0.2 8.9 0.0 0.0 7.8 0.0 0.1 2.0 0.0 2.0 0.0 1.5 16.8 0.6 0.3 0.0 22.8 0.0 0.0 0.8 2.1 4.2 0.0 1.5 1.8 74.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 6.8 0.3 0.0 0.0 0.3 0.0 0.0 4.7 0.4 0.1 1.3 0.1 0.1 0.3 0.4 0.4 0.0 0.0 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 57.7;Excitatory neurons: 228.7;Inhibitory neurons: 160.5;Microglial cells: 60.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 45.9;fHDF/TERT166: 74.5;U-266/70: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" 12.5 0.6 5.4 0.6 7.4 0.0 3.5 1.2 8.0 2.5 0.0 0.7 0.3 6.3 0.8 0.7 2.1 1.2 4.5 6.9 7.2 1.0 0.1 5.5 0.5 17.3 6.5 0.5 0.7 1.3 0.2 10.0 7.0 2.0 0.7 4.0 1.2 2.7 5.4 1.7 0.4 4.7 11.8 0.7 0.5 0.4 5.1 0.6 9.1 7.5 0.6 0.7 0.7 15.2 0.0 0.8 0.1 0.0 13.9 0.8 0.0 11.6 1.1 9.8 0.9 0.0 0.1 45.9 1.7 74.5 0.0 2.0 0.0 0.0 5.6 0.0 0.3 0.0 0.6 0.0 0.7 0.0 0.1 3.3 0.3 0.0 1.2 5.5 9.7 0.0 0.0 6.1 1.3 0.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 1.7 1.3 0.0 0.3 0.1 0.0 2.1 5.3 0.0 15.3 7.9 2.3 0.1 0.9 32.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 7.4 1.2 8.0 6.9 7.2 17.3 6.5 7.0 11.8 5.1 15.2 57.7 25.6 0.6 15.3 0.8 3.3 0.5 0.0 0.0 7.8 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.3 3.6 0.2 1.9 14.8 1.2 0.0 228.7 0.4 0.1 3.7 0.0 0.5 0.0 0.2 8.6 0.0 2.3 0.0 160.5 0.2 0.0 0.3 2.0 11.9 0.3 0.3 5.4 60.0 0.0 0.7 0.0 33.7 7.2 0.7 0.1 0.0 0.1 0.3 0.0 0.3 0.0 1.5 0.0 10.0 2.7 0.2 0.8 0.1 1.3 0.1 0.1 3.6 0.9 0.3 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 141.6" "Cell type enriched" "Detected in some" 5 "Theca cells: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 8.2;HUVEC TERT2: 9.0;NTERA-2: 4.6;RH-30: 3.2;SCLC-21H: 7.7;TIME: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Supported Nucleoplasm NA NA "Cluster 64: Macrophages - Immune response" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" 15.9 5.4 7.2 1.6 7.3 0.0 15.0 9.5 6.8 8.7 4.2 4.6 1.3 8.9 0.6 3.7 7.7 2.5 23.2 6.1 5.8 13.3 2.2 11.8 1.5 6.8 6.4 3.6 2.6 1.4 4.1 7.8 7.0 5.8 1.1 0.4 3.4 1.8 4.8 3.9 5.4 3.3 6.1 141.6 4.2 1.6 7.3 0.8 10.2 4.8 0.9 6.4 6.3 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 9.0 0.9 0.0 0.0 0.0 2.4 0.0 0.0 4.6 0.1 0.0 0.6 3.2 0.1 0.0 0.0 7.7 0.9 0.2 0.0 0.0 1.1 2.5 0.0 4.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 7.3 9.5 6.8 6.1 5.8 6.8 6.4 7.0 6.1 7.3 5.2 45.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.6 0.5 0.6 4.6 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.2 32.1 0.0 0.0 2.9 0.2 0.0 1.0 0.0 0.2 0.0 4.3 24.3 0.0 0.0 3.3 2.4 0.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.6 1.8 0.3 0.6 0.1 0.3 0.0 0.1 248.7 0.0 0.1 CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 35.0;Erythroid cells: 26.5;Hofbauer cells: 42.7;Kupffer cells: 22.1;Langerhans cells: 36.5;Macrophages: 56.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 21.0;OE19: 8.4;PC-3: 15.3;RT4: 8.3;TIME: 15.4;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043238 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" 11.7 1.6 2.1 11.4 2.1 9.0 8.4 2.2 3.7 2.3 2.2 11.5 11.7 1.2 0.6 0.9 1.1 5.5 2.7 2.1 2.2 2.2 4.4 12.4 4.9 2.8 2.3 0.5 1.5 0.8 0.8 5.1 3.1 0.8 10.4 0.2 0.9 0.8 1.1 0.7 12.1 2.5 2.6 8.5 5.5 0.3 2.9 7.7 1.3 1.1 3.8 6.0 1.1 3.3 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.2 0.0 0.2 0.0 0.0 2.8 0.0 0.0 0.3 0.7 4.6 0.0 21.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 5.0 0.2 0.0 7.2 4.2 2.8 0.1 5.0 0.0 1.6 2.6 0.0 8.4 15.3 0.4 0.3 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 15.4 0.6 0.3 0.7 0.3 0.0 8.6 0.2 7.5 6.5 0.0 8.7 15.4 4.3 2.8 22.1 3.4 1.7 1.6 4.7 9.9 3.9 1.0 2.5 2.6 6.7 10.1 3.0 4.7 5.0 2.1 2.1 2.2 3.7 2.1 2.2 2.8 2.3 3.1 2.6 2.9 3.3 35.0 0.0 4.7 0.0 4.4 2.0 0.2 0.2 0.0 0.0 0.4 0.4 1.1 1.5 1.2 0.0 0.0 0.3 4.5 19.5 0.0 0.6 0.1 0.1 0.2 12.1 0.0 26.5 0.0 8.8 1.2 1.4 4.6 0.1 9.5 0.1 6.4 0.4 42.7 0.0 0.0 16.6 0.0 22.1 36.5 0.0 0.0 56.2 1.8 1.9 6.7 0.0 0.0 0.0 0.0 9.8 12.4 0.0 4.2 0.2 17.2 0.2 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 1.1 2.5 6.4 0.4 9.2 1.1 CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1533.6" "Cell type enhanced" "Detected in many" "Adipocytes: 3219.2;Cardiomyocytes: 623.1;Hofbauer cells: 1369.8;Sertoli cells: 696.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 962.6;intermediate monocyte: 270.6;myeloid DC: 507.1" "Group enriched" "Detected in all" 46 "dendritic cells: 507.1;monocytes: 962.6" "Group enriched" "Detected in some" 4 "ASC diff: 322.6;HEL: 158.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 16.9" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" 1533.6 24.6 3.4 51.7 2.5 148.2 540.4 1.6 2.0 11.6 2.7 40.5 113.6 8.7 38.2 19.6 40.5 84.0 540.9 2.6 6.9 7.0 80.8 131.2 18.8 22.0 21.2 4.0 31.2 25.0 2.0 413.3 15.7 5.0 40.9 0.3 31.9 8.6 248.5 28.6 119.7 39.4 14.0 309.9 31.2 7.7 24.0 22.1 69.1 381.6 7.2 22.2 13.4 3.9 0.0 0.0 1.0 0.2 322.6 3.3 0.7 0.9 10.7 0.1 0.1 0.0 0.0 0.1 0.6 1.4 0.3 0.1 4.3 0.5 0.1 0.6 0.4 158.1 0.5 25.7 0.2 0.1 0.1 31.0 12.6 0.1 0.2 7.7 0.9 0.0 5.8 0.0 1.8 0.2 0.1 1.0 0.0 0.0 0.0 0.2 0.0 0.5 0.5 0.1 0.9 1.3 0.8 0.6 0.3 2.7 11.1 19.3 0.4 0.5 0.5 0.6 0.3 0.2 0.8 0.4 0.1 54.3 41.8 12.3 962.6 3.7 1.9 270.6 2.1 3.6 0.6 0.6 507.1 0.5 0.8 0.4 15.8 5.9 72.0 128.3 1.5 692.4 3.4 2.5 1.6 2.0 2.6 6.9 22.0 21.2 15.7 14.0 24.0 3.9 3219.2 6.4 63.1 0.0 7.9 7.4 0.2 3.0 0.6 0.2 189.9 24.8 623.1 4.3 9.8 7.3 0.0 10.1 55.0 0.0 0.0 0.2 11.7 5.0 5.9 303.3 0.0 419.5 6.3 0.0 11.1 69.6 1.1 38.4 15.2 0.6 406.2 9.0 1369.8 0.0 2.2 0.6 8.2 153.7 67.3 3.9 0.6 159.6 16.0 17.8 255.2 0.0 7.2 0.5 1.3 0.1 0.0 0.0 4.2 0.8 9.9 0.4 1.2 0.3 696.8 33.1 452.1 4.6 0.7 0.8 4.7 18.3 5.9 1.9 0.2 0.3 CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 101.5;Oligodendrocytes: 259.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 134.8;TIME: 160.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA015325: AB_1855090" "unprognostic (4.35e-1)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.50e-1)" "unprognostic (4.96e-3)" "unprognostic (5.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.23e-2)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.09e-6)" "unprognostic (4.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.92e-2)" "unprognostic (1.70e-2)" 21.4 11.2 26.3 18.9 45.9 48.1 18.4 23.0 34.7 13.2 8.3 17.0 11.9 26.2 9.1 14.6 13.9 16.2 11.4 36.7 28.6 11.6 16.3 20.6 21.7 23.2 23.0 15.7 10.5 10.6 8.0 31.8 23.0 14.0 12.2 19.3 8.7 11.1 8.8 11.0 11.5 29.5 27.4 21.8 10.5 26.6 28.5 24.8 11.6 12.3 22.2 17.1 12.8 54.0 15.4 12.5 32.5 8.9 15.9 41.2 24.1 34.8 46.9 29.1 27.2 7.7 8.8 22.7 23.0 24.5 15.6 13.8 19.8 20.9 39.5 24.9 15.5 32.7 8.5 10.9 34.4 17.9 18.4 30.0 21.3 43.0 77.1 51.8 134.8 18.9 24.7 18.1 66.8 9.5 17.0 28.1 14.4 7.6 22.8 29.2 18.0 19.8 35.1 12.7 17.1 11.7 19.9 18.4 25.9 24.7 14.0 15.7 160.5 25.6 10.0 13.8 18.7 26.0 21.1 24.1 9.6 7.6 19.2 66.7 6.4 17.1 22.2 9.3 24.0 17.5 17.9 25.1 10.0 16.6 25.0 21.7 23.2 31.4 9.0 7.3 15.8 16.6 26.3 45.9 23.0 34.7 36.7 28.6 23.2 23.0 23.0 27.4 28.5 54.0 58.1 16.0 6.5 54.5 37.3 26.8 10.7 8.6 19.4 11.8 13.8 9.8 11.9 7.2 10.3 9.2 16.7 12.0 64.4 7.2 0.0 4.9 3.3 17.6 10.0 51.7 15.0 17.9 101.5 3.6 27.9 24.0 21.4 17.2 18.3 8.9 34.2 10.8 12.1 5.0 59.2 7.9 4.1 14.5 20.7 4.1 9.9 16.7 17.8 64.6 8.6 22.6 32.0 52.3 259.2 7.4 3.4 9.4 64.7 12.5 6.5 8.6 15.4 9.6 6.6 22.7 22.0 8.8 21.6 24.2 25.9 13.7 63.2 10.7 6.0 15.1 CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109740694-109801999 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1098.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 592.5;Muller glia cells: 147.8;Proximal tubular cells: 223.6" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 106.1;Hep G2: 179.8;HSkMC: 67.4;RPTEC TERT1: 190.6" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" NA NA 12000000000 "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" 45.1 50.2 8.1 12.6 8.2 0.1 17.4 7.7 13.2 36.8 10.4 7.4 38.0 39.2 80.3 9.3 74.0 73.0 25.0 8.3 9.6 224.9 1098.8 50.7 8.9 15.6 10.2 32.1 26.0 3.1 8.4 24.1 10.7 8.3 6.4 53.0 15.0 26.7 3.9 2.7 22.3 24.3 10.5 33.1 14.4 8.8 9.2 2.3 14.5 4.6 7.5 34.1 8.3 10.6 0.0 0.6 0.0 0.3 0.0 0.2 0.1 1.5 1.4 0.1 0.2 0.0 106.1 0.0 32.9 0.0 0.5 0.0 0.0 0.0 0.0 34.8 0.7 0.0 0.4 179.8 6.2 0.3 0.0 67.4 0.0 0.1 0.0 3.6 4.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 190.6 0.5 0.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.0 0.1 18.8 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 8.2 7.7 13.2 8.3 9.6 15.6 10.2 10.7 10.5 9.2 10.6 48.1 12.8 50.9 3.6 4.0 1.0 12.2 15.2 0.6 3.4 2.1 5.6 2.3 108.7 36.2 64.4 2.1 0.1 0.3 1.7 31.3 69.3 0.2 34.1 46.4 57.7 0.0 2.7 0.3 30.9 0.2 34.3 8.2 33.6 3.8 72.1 55.0 592.5 0.7 1.7 0.2 1.9 0.0 16.7 1.5 0.8 16.8 2.0 0.0 4.7 1.6 147.8 0.0 0.0 0.3 30.8 2.4 0.0 0.0 3.8 17.0 223.6 8.4 7.3 0.0 1.3 9.4 1.6 0.5 1.9 1.1 0.3 3.4 18.5 4.1 12.6 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 DLL4 ENSG00000128917 "Delta like canonical Notch ligand 4" Q9NR61 15 40929340-40939073 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Angiogenesis, Differentiation, Neurogenesis, Notch signaling pathway, Sensory transduction, Vision" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 70.7;Distal enterocytes: 24.2;Endothelial cells: 48.6;Hepatic stellate cells: 30.4;Intestinal goblet cells: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BJ hTERT+: 59.4;HUVEC TERT2: 15.7;SCLC-21H: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023392 Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA023392: AB_1847740" "unprognostic (1.92e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (7.52e-2)" "unprognostic (4.71e-2)" "unprognostic (2.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.56e-2)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (2.73e-1)" "unprognostic (3.51e-2)" "unprognostic (6.10e-2)" "unprognostic (2.56e-3)" "unprognostic (9.92e-2)" "unprognostic (2.93e-1)" "unprognostic (1.51e-2)" "unprognostic (5.51e-3)" 25.2 2.6 6.9 2.9 6.1 0.3 21.2 6.5 7.0 8.0 4.9 7.6 4.0 8.8 1.0 3.7 7.6 3.7 23.8 5.8 6.0 10.0 3.5 22.5 5.0 7.1 6.5 4.1 2.9 2.9 5.6 19.8 7.5 7.9 3.0 0.9 4.3 2.7 10.0 5.5 6.8 4.2 6.6 4.6 4.8 1.5 8.4 5.0 15.4 10.6 1.7 8.7 7.6 6.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.9 59.4 0.2 0.3 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 0.4 1.1 0.1 0.1 0.0 0.6 0.0 0.9 0.0 1.4 0.5 1.6 0.0 0.1 32.5 0.0 0.3 0.7 0.0 0.0 0.0 3.5 0.9 0.0 0.1 0.0 0.0 1.3 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 6.1 6.5 7.0 5.8 6.0 7.1 6.5 7.5 6.6 8.4 6.2 70.7 0.0 2.7 0.0 1.7 1.3 0.2 0.2 4.0 4.9 1.6 2.8 3.2 1.5 0.9 0.0 0.0 1.5 0.2 24.2 0.0 0.2 0.2 1.9 0.7 48.6 17.4 0.0 0.9 0.2 0.6 3.1 13.3 2.6 2.5 0.0 30.4 0.1 0.2 0.0 0.6 36.3 6.1 1.6 0.8 0.3 0.0 0.8 1.8 11.2 0.0 0.2 0.0 0.5 0.5 0.2 16.7 0.0 3.5 2.3 9.2 0.0 0.2 1.4 0.0 0.9 3.8 0.8 2.0 1.0 1.6 1.9 0.4 0.4 12.0 0.6 DOC2B DOC2BL ENSG00000272636 "Double C2 domain beta" Q14184 17 142789-181650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 24.6" "Group enriched" "Detected in many" 5 "Adipocytes: 49.4;Cone photoreceptor cells: 175.2;Muller glia cells: 146.7;Rod photoreceptor cells: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 37.2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 56.1" HPA043168 Uncertain NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "HPA043168: AB_2678349" "prognostic favorable (3.45e-4)" "unprognostic (2.28e-3)" "unprognostic (3.17e-1)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "prognostic favorable (8.68e-4)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.78e-3)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (2.27e-3)" "unprognostic (2.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-3)" "unprognostic (4.87e-3)" 15.9 4.5 11.6 3.0 12.7 6.2 13.9 18.6 21.1 3.7 1.3 4.0 0.0 4.0 0.0 14.4 5.8 0.0 5.3 22.5 6.5 8.7 0.7 3.4 1.3 8.7 11.7 1.1 10.0 0.2 6.7 1.4 10.8 3.6 1.1 24.6 2.1 0.6 2.7 4.4 4.5 1.5 12.6 3.3 3.4 0.3 12.2 0.8 3.0 0.1 2.5 4.4 5.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 12.7 18.6 21.1 22.5 6.5 8.7 11.7 10.8 12.6 12.2 0.9 49.4 0.0 2.3 0.3 0.2 0.0 0.8 0.0 2.2 10.1 1.5 1.3 2.0 0.0 0.0 9.2 175.2 0.0 0.0 0.2 0.0 0.2 1.1 0.7 4.6 22.8 0.0 0.0 3.8 4.2 0.0 2.3 9.2 0.8 0.0 0.1 18.5 0.2 0.1 1.7 2.3 0.0 0.0 0.3 0.0 2.5 0.0 0.5 0.0 1.0 0.6 146.7 0.0 1.5 0.1 4.3 0.0 0.0 0.0 0.9 0.0 0.5 1.5 100.7 0.0 2.3 0.8 0.2 0.1 1.8 0.0 0.3 0.1 0.8 0.2 3.6 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.7;Endothelial cells: 148.0;Hepatic stellate cells: 160.6;Respiratory ciliated cells: 103.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" 37.1 14.4 5.4 34.2 6.1 18.4 28.4 14.4 5.8 28.0 11.7 15.6 9.2 35.2 9.3 38.1 16.9 30.2 23.9 4.7 7.2 14.0 10.8 27.5 38.0 9.1 7.9 10.2 9.0 11.6 5.8 27.0 7.9 13.1 13.9 2.9 15.3 15.3 11.2 12.5 13.5 37.9 7.0 41.8 14.8 8.6 8.3 19.7 21.8 22.2 37.5 29.2 24.5 6.6 50.3 29.5 29.7 15.8 73.7 137.3 7.6 62.3 118.5 48.6 37.3 1.7 36.6 8.0 20.9 70.4 36.4 17.6 3.3 99.8 85.0 21.7 11.4 2.5 12.2 11.2 22.3 24.2 5.7 81.3 18.4 100.4 75.4 98.5 117.8 6.0 6.0 32.3 166.4 7.6 4.8 16.4 36.3 7.1 38.8 39.7 49.8 9.1 41.7 13.0 1.4 31.4 20.5 9.1 32.0 44.7 5.0 13.3 73.2 132.4 52.2 82.5 54.8 61.7 55.0 1.8 47.0 28.2 94.1 7.1 23.5 0.5 11.1 13.0 42.5 23.2 25.7 15.0 17.7 19.0 15.4 11.4 7.4 20.1 12.1 7.1 45.4 12.8 5.4 6.1 14.4 5.8 4.7 7.2 9.1 7.9 7.9 7.0 8.3 6.6 170.7 6.4 22.3 3.9 22.3 32.6 44.6 15.0 10.8 0.7 7.1 8.1 6.6 2.8 39.4 5.5 4.2 1.2 27.5 2.1 5.9 21.8 1.0 49.0 19.7 148.0 1.2 12.4 4.2 15.6 3.9 35.2 3.1 44.0 17.1 1.3 160.6 4.3 24.5 0.0 1.9 3.4 2.0 32.0 39.7 2.5 11.5 31.4 12.4 39.4 23.6 5.8 9.2 5.5 5.3 56.8 3.4 10.5 29.5 45.7 0.5 0.7 103.1 0.6 13.1 27.7 19.9 0.2 12.6 24.4 27.0 1.1 32.6 10.6 3.0 79.0 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 FAM110D "FLJ14050, GRRP1" ENSG00000197245 "Family with sequence similarity 110 member D" Q8TAY7 1 26159079-26163962 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 82.7;Endothelial cells: 63.5;Hepatic stellate cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "TIME: 1.2;U-2 OS: 1.4;U-937: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013664 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA013664: AB_1234332" "unprognostic (7.53e-2)" "unprognostic (4.45e-3)" "unprognostic (4.80e-4)" "unprognostic (1.84e-2)" "unprognostic (1.07e-3)" "unprognostic (3.16e-3)" "unprognostic (7.67e-5)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (4.51e-2)" "unprognostic (7.29e-3)" "unprognostic (6.63e-2)" "unprognostic (9.87e-2)" "unprognostic (6.94e-2)" "unprognostic (2.91e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-1)" 10.9 1.3 4.1 0.6 3.0 0.8 8.5 3.1 3.7 4.8 2.0 2.9 1.1 7.9 0.8 1.9 7.4 2.3 6.2 3.1 3.2 4.0 0.4 4.2 1.1 4.7 3.6 1.3 2.2 1.1 1.3 0.6 4.1 3.1 0.5 0.3 2.4 0.7 4.2 3.0 3.1 2.8 4.5 0.8 3.3 0.6 4.1 0.9 4.7 2.1 0.4 4.0 3.6 3.3 0.1 0.1 0.5 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.5 0.1 0.0 0.1 0.4 0.1 0.2 1.2 0.1 1.4 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 1.3 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 1.0 0.4 0.1 0.2 0.0 0.0 4.1 3.0 3.1 3.7 3.1 3.2 4.7 3.6 4.1 4.5 4.1 3.3 82.7 0.0 3.4 0.3 0.9 1.0 0.9 0.0 2.2 2.3 1.3 1.8 3.1 2.8 1.3 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.4 0.2 0.5 63.5 0.0 2.7 0.4 0.0 0.0 2.5 0.0 0.2 0.0 0.3 34.6 0.0 0.0 1.7 0.7 0.0 0.0 1.3 1.8 0.5 0.6 0.4 0.0 4.7 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 1.4 0.0 1.4 1.8 0.2 0.7 0.8 0.9 0.3 0.3 0.5 0.0 0.3 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Paneth cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.2;granulocytes: 974.2;monocytes: 1013.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 1749.2;TIME: 1929.6" "CAB004639, HPA051798" Uncertain NA NA 12000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004639: AB_425434, HPA051798: AB_2681615" "unprognostic (4.09e-2)" "unprognostic (2.29e-1)" "unprognostic (5.22e-3)" "unprognostic (1.28e-2)" "unprognostic (2.66e-1)" "unprognostic (7.18e-3)" "prognostic unfavorable (3.44e-7)" "unprognostic (7.05e-3)" "unprognostic (2.76e-1)" "unprognostic (8.81e-2)" "unprognostic (5.12e-3)" "unprognostic (6.65e-2)" "prognostic unfavorable (6.69e-5)" "unprognostic (1.97e-2)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" 272.7 185.0 138.4 178.8 177.5 167.0 188.2 88.5 163.2 123.0 112.6 158.6 108.9 165.4 150.1 169.8 131.7 104.5 171.4 166.7 115.8 186.7 98.1 235.2 162.7 92.4 98.9 135.1 114.6 123.0 79.5 218.7 95.6 125.4 188.5 11.8 111.0 119.8 110.3 127.3 117.0 225.1 97.8 185.7 118.3 56.9 120.5 188.1 190.9 150.6 202.2 206.8 126.2 118.9 718.1 299.5 172.9 240.3 654.1 771.3 202.9 423.9 337.1 382.7 354.2 278.4 295.2 272.5 149.3 555.7 656.3 337.7 255.1 1007.2 419.7 68.8 170.5 284.2 113.9 473.3 406.4 390.5 168.0 484.7 332.0 410.3 412.6 513.3 1749.2 401.0 271.0 145.8 443.3 125.8 401.9 453.7 307.1 335.3 276.4 307.0 254.1 351.9 540.0 243.4 248.7 173.8 208.0 479.3 728.8 231.8 177.2 293.0 1929.6 1363.6 201.8 278.1 329.5 76.4 168.1 292.9 248.1 332.3 307.5 316.3 870.8 974.2 112.9 1005.8 104.3 128.1 135.5 133.2 675.2 136.2 140.1 132.6 805.0 160.6 1013.4 312.7 195.0 1153.8 138.4 177.5 88.5 163.2 166.7 115.8 92.4 98.9 95.6 97.8 120.5 118.9 779.1 86.6 77.2 0.0 160.6 263.1 211.2 393.3 152.0 17.6 175.6 156.5 59.7 170.1 179.5 172.9 0.0 281.8 148.3 456.2 238.7 432.4 47.7 98.7 183.8 814.8 330.6 196.4 0.0 337.5 702.0 212.2 160.0 122.5 143.5 95.3 623.6 113.5 746.7 35.3 0.0 245.9 329.6 541.8 436.5 52.2 200.0 428.8 241.9 0.0 527.4 52.2 152.4 0.0 0.0 483.6 977.5 162.9 214.8 221.1 210.8 332.1 123.0 11.7 138.1 87.4 224.7 169.3 141.8 329.4 299.3 231.5 150.1 347.3 318.0 245.7 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GARRE1 KIAA0355 ENSG00000166398 "Granule associated Rac and RHOG effector 1" O15063 19 34254552-34355566 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 126.8;Cardiomyocytes: 15.7;Cytotrophoblasts: 23.8;Extravillous trophoblasts: 25.1;Syncytiotrophoblasts: 34.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014570 Uncertain Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA014570: AB_1852307" "unprognostic (1.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-3)" "unprognostic (9.05e-2)" "unprognostic (8.27e-2)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.34e-1)" "unprognostic (7.73e-3)" "unprognostic (2.96e-2)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" 18.8 5.6 5.0 7.2 6.7 3.4 16.8 7.3 4.5 10.8 6.7 7.8 5.4 11.0 3.0 8.0 10.1 9.5 12.0 3.6 5.6 8.2 7.3 12.4 9.1 7.0 7.0 9.4 10.4 10.8 7.7 23.3 6.6 8.3 5.6 8.1 7.4 6.4 15.4 10.3 8.2 8.6 5.2 16.1 6.6 7.1 7.1 8.5 10.9 17.0 7.5 8.0 9.9 10.3 3.4 10.2 8.9 4.6 6.0 5.7 11.6 7.6 6.2 5.7 8.4 8.1 3.9 7.7 16.4 7.1 7.1 2.4 6.6 3.6 6.2 11.0 5.8 4.7 3.9 6.2 7.6 2.1 3.7 6.7 6.2 7.5 11.0 22.6 23.7 4.3 14.4 3.8 6.2 1.8 1.4 1.9 6.8 4.6 3.7 3.4 6.2 4.1 4.8 3.8 10.3 8.5 8.7 33.9 10.9 12.9 2.7 3.8 19.7 19.5 7.2 5.0 8.1 6.4 9.5 2.4 3.7 0.8 9.7 0.0 0.7 0.0 0.8 1.4 1.3 2.3 1.8 0.8 0.8 2.8 1.6 1.0 2.2 1.5 2.1 1.1 3.0 0.8 5.0 6.7 7.3 4.5 3.6 5.6 7.0 7.0 6.6 5.2 7.1 10.3 126.8 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 23.8 10.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 25.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 34.1 2.3 0.0 0.0 0.0 GIMAP1 "HIMAP1, IAN2, IMAP1, IMAP38" ENSG00000213203 "GTPase, IMAP family member 1" Q8WWP7 7 150716606-150724284 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.8;Endothelial cells: 109.9;Hepatic stellate cells: 117.8;Kupffer cells: 109.1;monocytes: 74.9;NK-cells: 185.3;T-cells: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 14.7;MOLT-4: 9.2;TIME: 3.9" "Low region specificity" "Detected in many" "HPA044887, HPA053441" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum" "HPA044887: AB_10960351, HPA053441: AB_2682152" "unprognostic (1.60e-2)" "unprognostic (6.58e-3)" "unprognostic (8.21e-3)" "unprognostic (2.54e-3)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "prognostic favorable (1.09e-4)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.44e-1)" "unprognostic (4.60e-3)" "unprognostic (7.89e-2)" "unprognostic (1.77e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.12e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-1)" 9.8 2.5 3.0 11.0 3.0 1.0 7.9 2.9 3.5 3.8 3.0 3.7 3.5 4.6 1.1 2.1 4.4 3.2 9.3 2.8 2.9 3.5 2.4 8.9 19.6 3.5 3.2 1.5 1.4 1.5 1.1 7.1 3.4 2.3 2.2 0.1 2.5 2.0 5.4 2.5 6.9 3.8 3.5 24.7 3.3 0.8 3.6 6.6 5.3 7.1 8.4 3.5 3.0 3.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 14.7 1.9 0.0 0.0 0.0 0.0 9.2 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 3.0 32.2 0.1 43.8 29.6 51.1 0.3 47.5 54.2 13.5 0.6 68.2 56.2 2.7 42.6 30.6 0.8 34.0 35.0 3.0 3.0 2.9 3.5 2.8 2.9 3.5 3.2 3.4 3.5 3.6 3.2 189.8 3.2 1.5 0.0 5.1 5.5 0.6 0.0 1.2 0.6 1.9 3.6 5.9 2.8 0.6 0.0 0.0 0.3 51.5 0.1 0.0 0.3 0.3 0.4 0.6 109.9 0.0 10.5 0.0 0.4 0.3 3.7 1.5 0.2 8.2 0.2 117.8 2.0 37.9 0.0 0.0 0.0 0.0 109.1 7.6 1.3 1.5 48.0 8.8 0.0 74.9 0.3 185.3 0.0 0.0 0.1 0.1 0.0 7.6 0.7 0.2 0.5 0.0 1.0 0.0 2.5 3.5 0.3 0.5 0.7 3.1 0.4 97.3 1.0 0.0 0.7 GIMAP6 "FLJ22690, IAN6" ENSG00000133561 "GTPase, IMAP family member 6" Q6P9H5 7 150625375-150632648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.3;Endothelial cells: 83.5;Hepatic stellate cells: 92.1;Kupffer cells: 75.2;monocytes: 37.4;NK-cells: 91.6;T-cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "monocytes: 75.1;NK-cells: 217.3;T-cells: 127.2" "Cell line enhanced" "Detected in some" "HMC-1: 18.4;HUVEC TERT2: 124.9;MOLT-4: 43.3;TIME: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026715, HPA050740" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA026715: AB_1849675, HPA050740: AB_2797239" "unprognostic (8.58e-2)" "unprognostic (1.34e-2)" "unprognostic (6.56e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.22e-1)" "prognostic favorable (2.91e-4)" "prognostic favorable (1.56e-4)" "unprognostic (2.88e-2)" "unprognostic (8.75e-2)" "unprognostic (8.87e-2)" "unprognostic (4.68e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.75e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" 42.0 9.4 9.7 33.9 9.7 2.5 21.8 9.7 10.6 14.9 8.0 12.0 13.6 19.3 7.3 8.4 16.9 14.7 29.1 8.0 9.5 12.4 12.7 38.8 50.2 11.4 10.5 5.7 5.2 8.0 3.3 32.3 11.3 6.4 12.2 0.6 7.8 10.0 24.7 6.4 18.7 25.8 10.9 64.0 11.6 3.2 11.6 29.3 14.2 34.7 33.9 16.5 6.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 3.8 0.0 6.3 0.0 0.0 0.0 0.4 18.4 0.1 0.0 0.0 0.0 0.0 124.9 0.5 0.0 4.6 0.0 0.0 43.3 5.4 0.0 0.0 0.0 4.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.8 35.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 13.0 0.0 11.6 58.1 2.1 112.9 75.1 127.2 0.4 104.3 120.2 22.1 0.3 108.3 103.0 8.0 217.3 60.2 0.7 105.7 163.5 9.7 9.7 9.7 10.6 8.0 9.5 11.4 10.5 11.3 10.9 11.6 10.1 95.3 0.0 1.1 0.0 3.1 3.8 0.1 0.0 0.6 0.0 1.1 1.0 7.4 0.0 0.0 0.0 0.0 0.2 24.5 0.1 0.0 0.0 0.4 0.1 0.2 83.5 0.0 19.4 0.0 0.2 0.3 3.4 0.0 0.2 2.5 0.3 92.1 1.7 30.6 0.0 0.0 0.1 0.0 75.2 6.5 2.2 1.2 20.0 1.8 13.1 37.4 0.1 91.6 0.0 0.1 0.1 0.0 0.0 2.9 0.1 0.0 0.2 0.7 0.4 0.0 2.6 2.2 0.3 0.1 0.4 3.1 0.4 41.2 1.2 0.0 0.3 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GJA4 CX37 ENSG00000187513 "Gap junction protein alpha 4" P35212 1 34792999-34795747 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 234.2;Sertoli cells: 664.0;Smooth muscle cells: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 74.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047981 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "HPA047981: AB_2680228" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.12e-2)" "unprognostic (2.67e-2)" "unprognostic (4.48e-1)" "unprognostic (5.24e-3)" "prognostic favorable (3.28e-4)" "unprognostic (2.01e-2)" "unprognostic (2.23e-1)" "unprognostic (8.17e-2)" "unprognostic (6.83e-2)" "unprognostic (8.81e-2)" "prognostic unfavorable (7.44e-4)" "unprognostic (3.47e-2)" "unprognostic (3.74e-2)" "unprognostic (3.82e-3)" "unprognostic (7.96e-3)" 79.4 20.4 10.1 9.3 11.0 0.3 61.5 9.8 15.1 26.6 9.0 14.7 2.8 33.8 5.5 7.5 40.0 17.3 83.6 10.5 9.6 35.8 17.3 40.7 11.3 10.3 10.2 18.0 7.0 10.6 6.4 61.6 10.6 18.8 3.8 0.8 10.1 10.7 34.7 14.8 13.9 15.2 10.2 9.9 12.9 5.4 10.2 2.7 39.8 35.2 5.4 28.1 22.4 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 10.1 11.0 9.8 15.1 10.5 9.6 10.3 10.2 10.6 10.2 10.2 9.9 90.4 0.0 0.0 0.3 0.6 9.7 1.9 0.2 1.2 0.2 1.1 1.5 9.0 1.5 0.6 3.7 0.0 0.2 0.7 0.0 0.0 11.0 0.1 3.1 0.5 81.4 15.6 2.7 0.0 0.0 0.1 7.7 2.6 4.9 0.0 0.5 234.2 1.8 0.3 0.0 0.0 0.0 0.0 6.3 10.7 1.1 0.9 2.2 19.6 1.0 0.6 0.1 0.0 0.0 0.0 1.0 0.0 12.8 0.2 3.0 0.0 0.1 1.2 0.7 664.0 4.4 306.3 0.2 1.2 0.7 8.7 0.0 1.3 1.6 0.1 5.2 GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1903.6;Endothelial cells: 1236.2;Hepatic stellate cells: 994.2;Macrophages: 481.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cell line enhanced" "Detected in many" "EFO-21: 219.9;HUVEC TERT2: 349.6;SK-MEL-30: 221.8;TIME: 201.1;U-87 MG: 187.1" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" 75.5 16.8 14.4 8.1 14.6 2.5 64.4 14.7 22.0 24.9 13.7 23.5 6.7 26.8 10.9 10.9 33.5 15.5 48.3 14.1 14.7 34.9 12.1 39.8 7.8 14.9 14.6 56.7 8.8 4.4 9.3 85.9 15.3 15.8 6.4 1.5 9.1 17.9 15.4 11.4 16.1 16.7 15.1 39.0 16.0 3.3 16.1 19.0 29.1 18.6 3.5 27.9 18.4 14.9 0.2 34.2 67.2 31.0 51.2 40.0 0.0 34.8 67.7 19.0 26.7 0.1 2.9 0.0 219.9 17.5 79.9 0.5 0.5 3.2 23.8 0.2 2.0 11.0 35.9 0.0 81.8 0.0 0.1 13.4 0.1 61.0 6.0 78.7 349.6 0.0 0.1 0.2 85.9 0.0 0.1 0.1 5.8 0.0 10.4 32.5 7.6 0.1 41.3 0.0 0.1 67.2 0.0 0.2 221.8 8.6 144.4 2.4 201.1 93.4 10.4 68.3 3.9 0.0 0.2 0.7 187.1 0.0 81.8 20.5 0.7 0.3 0.1 0.1 0.2 2.3 0.0 0.0 1.0 2.0 0.2 0.0 9.8 0.0 0.1 3.7 0.1 50.2 14.4 14.6 14.7 22.0 14.1 14.7 14.9 14.6 15.3 15.1 16.1 14.9 1903.6 12.8 27.3 1.3 20.6 83.6 11.8 3.1 5.7 0.7 15.2 26.8 94.8 11.5 3.1 187.6 0.0 2.3 15.4 0.1 74.3 135.7 5.9 124.1 94.6 1236.2 0.0 40.6 0.0 5.7 12.9 207.3 0.5 236.4 2.5 12.7 994.2 11.1 17.0 0.0 0.0 0.3 18.3 55.9 89.5 17.0 82.3 481.1 188.5 26.2 49.6 9.2 41.2 0.5 0.2 4.3 0.0 86.9 8.0 11.0 0.0 12.9 1.7 4.7 151.2 115.5 165.0 1.9 7.6 2.7 65.8 23.8 15.9 109.9 0.0 4.5 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 96.9;Breast glandular cells: 34.3;Endometrial ciliated cells: 34.2;Endometrial stromal cells: 48.4;Granulosa cells: 41.4;Theca cells: 48.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA040719: AB_2677097" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (3.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.53e-1)" "unprognostic (2.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (4.68e-2)" "unprognostic (1.93e-3)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (3.55e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" 6.3 5.9 11.1 2.9 12.0 2.4 5.6 11.6 14.9 5.0 7.2 7.0 1.2 6.0 8.3 3.6 4.7 4.0 5.7 11.8 11.5 4.8 0.8 5.1 2.9 10.5 10.5 5.0 1.7 17.7 6.8 3.0 10.5 4.9 2.6 8.5 2.4 4.6 2.5 2.0 2.9 5.3 11.1 3.4 2.9 9.7 11.8 4.3 6.5 2.5 2.2 5.6 3.8 10.7 7.2 6.2 17.9 9.3 7.4 10.1 5.9 6.7 11.9 7.0 7.3 0.5 13.2 0.1 8.0 1.8 7.5 2.9 19.9 10.3 10.1 33.5 10.2 11.6 3.0 0.1 10.3 0.4 1.8 6.0 8.4 8.0 13.9 10.8 17.0 12.4 9.0 0.3 13.2 7.4 7.1 0.7 13.3 0.0 3.5 0.1 17.4 0.1 10.5 14.6 22.5 17.1 10.1 2.4 8.9 12.9 2.8 1.3 14.7 14.5 10.8 3.0 20.9 2.1 0.8 8.6 6.7 5.5 10.0 0.7 0.3 1.0 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.8 1.8 0.1 0.2 0.0 0.1 11.1 12.0 11.6 14.9 11.8 11.5 10.5 10.5 10.5 11.1 11.8 10.7 96.9 12.8 17.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 34.3 27.3 0.0 0.0 10.5 20.2 0.0 0.3 14.1 0.0 15.6 21.1 0.0 34.2 48.4 25.8 0.0 0.0 0.0 22.9 0.6 15.4 0.0 25.6 5.1 41.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 23.6 0.0 0.0 3.1 0.0 0.0 0.3 9.5 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.3 3.5 48.1 0.0 0.0 HHEX "HEX, HOX11L-PEN, PRHX" ENSG00000152804 "Hematopoietically expressed homeobox" Q03014 10 92689955-92695647 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.7;liver: 91.2;thyroid gland: 102.1" "Cell type enhanced" "Detected in many" "B-cells: 77.2;Cholangiocytes: 125.8;dendritic cells: 57.6;Ductal cells: 107.9;Endothelial cells: 80.0;Hepatic stellate cells: 88.9;Hepatocytes: 58.3;Hofbauer cells: 72.6;Kupffer cells: 63.5" "Group enriched" "Detected in all" 5 "liver cancer: 20.1;thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 43 "basophil: 28.0;classical monocyte: 41.5;eosinophil: 61.8;intermediate monocyte: 45.7;memory B-cell: 59.3;myeloid DC: 30.8;naive B-cell: 65.8;neutrophil: 31.4;non-classical monocyte: 50.7;plasmacytoid DC: 36.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 87.7;HEL: 99.9;HMC-1: 105.6;HUVEC TERT2: 106.1;K-562: 154.8;NB-4: 101.8;U-937: 79.7" "Low region specificity" "Detected in many" "HPA003257, HPA051894" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear bodies" "HPA003257: , HPA051894: AB_2681653" "prognostic favorable (8.83e-4)" "prognostic favorable (3.91e-5)" "unprognostic (2.98e-2)" "unprognostic (7.92e-2)" "unprognostic (6.46e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (1.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-2)" "unprognostic (5.27e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.25e-5)" "unprognostic (8.82e-2)" "unprognostic (2.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.50e-2)" 16.2 18.5 5.0 22.2 5.4 84.7 11.2 5.6 8.8 7.1 5.1 7.8 6.4 6.4 3.5 4.1 6.1 27.4 6.1 4.8 5.2 7.0 91.2 16.9 39.1 6.3 5.4 3.0 38.1 1.9 2.2 14.6 6.4 4.7 6.5 0.3 3.5 4.0 2.9 4.6 19.0 5.8 6.2 39.9 5.2 2.4 6.0 4.4 102.1 6.3 30.4 12.7 5.0 6.7 11.2 20.6 10.5 0.1 0.9 0.7 0.2 5.6 46.4 7.4 6.6 4.0 2.6 10.7 87.7 0.7 0.0 2.1 9.5 0.3 9.1 0.1 11.1 99.9 8.8 67.4 21.0 58.6 105.6 0.3 0.2 6.5 0.0 3.7 106.1 0.3 154.8 0.1 0.5 3.2 0.4 101.8 0.2 30.2 11.8 34.0 3.0 0.1 0.9 4.3 4.9 1.0 6.2 0.0 0.1 0.5 3.3 30.6 37.2 0.0 0.6 0.1 0.1 2.6 1.8 21.2 0.0 79.7 51.4 28.0 41.5 61.8 0.8 45.7 0.3 59.3 0.0 0.1 30.8 65.8 0.1 0.1 31.4 1.0 50.7 36.3 0.4 15.5 5.0 5.4 5.6 8.8 4.8 5.2 6.3 5.4 6.4 6.2 6.0 6.7 31.9 0.0 3.0 0.0 77.2 6.4 2.1 0.9 2.2 0.0 3.0 3.2 3.6 125.8 1.6 0.0 0.0 0.7 57.6 0.4 0.0 107.9 0.3 0.8 0.5 80.0 5.3 28.2 0.0 12.0 0.7 2.2 0.5 1.0 7.0 0.0 88.9 58.3 72.6 0.0 0.0 1.6 0.0 63.5 29.1 1.1 0.3 51.7 7.2 5.6 50.4 0.0 9.2 0.5 0.0 10.5 0.0 1.2 1.6 3.2 0.0 0.2 0.9 0.2 0.0 1.9 2.1 0.3 6.3 1.0 3.7 1.1 8.3 3.4 0.7 1.3 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 65.0;Endothelial cells: 50.1;Hepatic stellate cells: 16.1;Late spermatids: 16.8;Microglial cells: 15.0;Peritubular cells: 15.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.9;EFO-21: 4.9;HUVEC TERT2: 9.5;TIME: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" 23.1 4.1 9.3 3.0 8.9 1.3 23.0 6.6 7.8 15.0 4.2 6.6 1.8 12.5 1.2 4.2 10.3 4.7 29.3 6.6 7.0 11.8 1.7 20.6 1.7 8.2 7.9 8.2 2.6 1.5 2.9 11.3 8.4 4.9 1.2 0.4 5.4 1.9 12.3 7.7 6.1 4.0 6.8 25.3 5.1 5.2 10.4 0.7 9.2 10.2 0.9 10.2 10.2 6.0 0.5 1.7 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.1 0.2 4.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 2.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 1.4 9.5 0.4 0.3 0.2 0.0 1.0 0.4 0.9 1.0 0.0 0.8 1.8 0.2 0.5 0.0 0.0 0.9 0.7 0.3 0.2 0.1 0.1 0.2 0.5 5.3 0.1 2.2 0.7 0.4 0.4 0.3 0.5 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 9.3 8.9 6.6 7.8 6.6 7.0 8.2 7.9 8.4 6.8 10.4 6.0 65.0 0.0 0.0 0.3 0.4 1.9 0.1 0.0 0.0 0.5 0.7 0.3 5.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.8 0.2 3.2 50.1 0.0 0.0 0.5 0.0 0.2 10.5 0.0 0.1 0.0 0.1 16.1 0.3 0.5 0.0 0.4 0.0 0.0 1.4 2.5 16.8 7.5 0.2 0.0 15.0 0.0 3.1 0.0 0.0 0.3 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.2 2.0 3.5 1.7 0.3 1.1 0.4 0.3 0.7 0.0 0.2 IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" Cytosol "CAB016293: AB_627775, HPA002134: AB_1079099, HPA073514: " "unprognostic (7.23e-3)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (7.70e-3)" "unprognostic (1.87e-1)" "unprognostic (6.08e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "unprognostic (5.04e-2)" "unprognostic (2.26e-2)" "unprognostic (5.92e-3)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (5.07e-2)" "unprognostic (4.08e-1)" "unprognostic (7.97e-2)" "unprognostic (1.14e-1)" 95.7 37.9 13.5 114.5 17.5 35.5 72.8 14.3 14.1 56.8 9.1 38.3 23.8 76.5 22.7 63.6 54.2 100.6 35.0 13.7 20.3 30.1 27.7 68.2 140.6 29.9 22.7 76.8 16.7 9.7 9.3 66.7 27.0 26.5 45.0 7.7 63.7 32.0 16.8 58.8 47.9 87.3 23.6 107.8 30.7 18.8 23.8 116.8 37.4 32.6 133.1 113.6 52.8 26.2 43.5 3.2 14.4 0.6 97.4 319.5 0.4 89.9 238.0 245.7 324.2 0.0 54.1 251.7 75.4 55.3 79.2 122.2 2.2 91.1 97.7 78.4 1.1 64.9 17.2 0.1 181.8 22.8 4.2 302.4 159.5 126.5 177.8 117.8 262.8 218.1 1.4 179.4 138.6 0.0 302.2 21.1 38.4 0.0 32.5 140.6 91.4 295.0 34.4 16.1 6.6 0.1 117.7 1.0 259.5 56.9 0.4 26.3 150.2 63.1 29.7 179.9 38.2 165.8 82.8 235.5 181.2 72.7 155.7 9.1 67.7 0.4 57.5 66.4 51.9 88.4 54.3 59.4 68.3 94.6 33.9 43.3 164.4 91.6 65.3 51.1 82.1 63.8 13.5 17.5 14.3 14.1 13.7 20.3 29.9 22.7 27.0 23.6 23.8 26.2 378.4 38.5 54.6 4.2 217.8 95.0 110.7 197.6 174.8 0.4 47.8 43.8 10.7 37.1 130.7 42.3 0.0 3.4 278.3 7.9 1.9 38.0 4.9 41.9 219.1 286.8 12.1 38.7 1.3 47.8 2.9 207.8 9.7 68.0 138.3 27.7 137.4 3.0 214.2 0.0 2.2 19.9 79.3 163.8 135.0 9.8 117.4 187.2 83.6 116.2 202.4 30.8 329.6 37.2 20.7 47.1 23.5 53.0 143.3 32.6 7.9 4.9 76.6 1.4 85.5 185.3 132.7 2.4 13.2 92.6 68.2 3.3 219.2 70.6 26.4 107.5 IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116698 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3792.9;Distal enterocytes: 2150.5;Endothelial cells: 1972.1;Exocrine glandular cells: 1603.8;Intestinal goblet cells: 1638.8;Pancreatic endocrine cells: 1678.1;Paneth cells: 2179.2;Proximal enterocytes: 3048.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.0" "Group enriched" "Detected in many" 6 "monocytes: 7.0;T-cells: 2.6" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 2026.8;BJ hTERT+ SV40 Large T+ RasG12V: 1782.5;EFO-21: 547.7;Karpas-707: 501.5;SK-MEL-30: 607.2" HPA028875 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" 470.3 323.3 178.3 115.7 177.4 162.8 410.3 180.9 232.6 351.4 162.7 374.4 129.2 137.8 39.9 310.4 163.2 344.1 471.5 174.5 182.4 217.9 150.4 608.2 48.3 203.8 187.7 75.6 39.3 30.3 65.3 183.8 215.0 85.0 221.4 6.1 156.9 47.0 113.1 129.8 256.2 117.4 194.9 797.8 697.0 140.2 194.1 202.8 149.8 152.4 54.2 116.9 213.7 190.8 181.3 0.4 1.3 0.4 0.5 21.7 1.7 2.8 8.8 2026.8 1782.5 3.8 146.8 1.5 547.7 115.3 33.8 5.7 1.1 0.2 79.7 2.1 3.7 1.0 1.4 0.9 13.7 0.6 1.1 2.0 2.0 353.8 0.1 1.1 284.0 1.3 1.1 501.5 0.1 0.5 1.7 1.1 0.5 0.5 24.7 1.8 0.5 0.6 1.2 0.6 0.4 1.1 0.0 0.1 607.2 1.4 0.9 3.0 0.3 0.2 2.7 325.8 1.0 9.4 14.6 3.9 0.9 0.5 1.4 0.0 1.3 0.5 0.3 7.0 0.3 0.0 2.6 0.7 0.8 0.1 0.0 0.4 0.0 0.4 2.1 0.1 2.5 2.1 178.3 177.4 180.9 232.6 174.5 182.4 203.8 187.7 215.0 194.9 194.1 190.8 3792.9 391.0 82.7 1.3 26.8 171.2 6.5 126.9 91.6 4.9 23.4 38.2 45.9 151.5 237.4 12.9 8.4 7.3 14.9 2150.5 1.9 50.6 13.6 1035.5 188.3 1972.1 267.8 42.3 0.6 1603.8 221.2 330.8 892.5 838.5 45.1 1174.4 742.5 5.8 158.3 5.0 0.4 1638.8 107.8 106.9 163.5 36.7 172.1 59.6 350.4 84.3 26.1 8.3 0.0 0.0 0.7 1678.1 2179.2 417.5 6.3 11.1 3048.1 23.7 548.1 20.5 276.1 45.2 295.8 20.3 12.1 151.9 140.4 5.2 34.1 302.4 523.4 80.4 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 186.3;Microglial cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 323.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" 41.4 22.4 53.9 32.3 53.8 9.0 18.7 44.8 56.5 17.0 29.4 44.4 12.7 19.1 13.5 32.0 9.4 23.1 14.4 49.8 50.0 25.0 42.3 20.2 33.7 53.5 50.2 18.4 11.3 12.9 7.5 28.0 53.0 35.9 16.1 11.8 10.2 66.0 10.7 6.1 13.2 46.1 56.7 21.0 13.1 11.0 55.2 14.6 21.5 18.9 38.9 34.8 9.5 52.6 56.7 78.2 40.9 30.2 22.9 58.5 59.1 44.2 323.1 36.6 35.4 64.6 40.4 86.4 52.4 45.5 192.7 3.3 50.7 112.3 46.6 8.8 10.1 36.8 71.4 46.5 195.6 10.9 11.9 74.5 61.9 55.5 137.7 134.1 73.7 13.8 28.2 17.0 87.1 23.8 11.5 19.6 12.6 14.3 75.5 20.9 53.7 2.1 31.3 23.0 2.8 29.7 25.0 8.0 21.8 49.0 19.3 22.9 94.2 96.8 65.4 25.5 53.8 19.3 18.7 79.0 78.6 28.3 22.9 5.4 2.2 0.4 0.7 3.2 1.1 5.1 1.4 0.8 2.5 3.7 1.1 0.5 2.3 1.0 1.4 0.9 0.2 0.8 53.9 53.8 44.8 56.5 49.8 50.0 53.5 50.2 53.0 56.7 55.2 52.6 74.9 16.0 1.1 45.7 38.0 3.7 9.4 22.9 7.4 18.8 16.5 11.2 4.5 17.2 33.7 11.0 4.2 1.0 6.3 0.3 17.6 39.3 2.8 4.0 11.1 43.6 1.2 10.9 46.1 21.0 57.9 12.6 3.1 5.3 2.5 9.5 22.9 35.6 13.3 70.7 186.3 0.4 12.2 25.4 25.8 6.6 8.1 28.6 17.8 190.2 27.5 12.1 7.2 69.9 79.0 24.3 0.1 13.9 43.0 31.5 2.0 21.8 32.7 3.4 0.0 14.2 17.3 9.8 5.6 3.3 3.4 5.7 10.7 32.4 0.7 14.1 LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 248.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062236 Enhanced Supported "Nuclear membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Nuclear membrane" "HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" 28.6 9.1 8.8 53.2 9.7 95.7 17.1 9.3 11.9 27.3 9.2 61.4 40.7 47.0 44.4 29.7 31.8 21.7 10.0 8.5 10.1 19.4 47.3 19.2 81.6 12.0 9.8 19.4 16.9 5.6 6.5 27.6 11.2 23.8 46.2 5.3 11.1 36.7 9.8 13.8 39.9 41.4 10.2 41.5 28.2 20.5 9.5 105.5 11.8 12.8 70.7 32.3 23.0 13.1 122.2 42.0 154.9 69.3 64.8 39.7 77.3 31.2 39.2 65.0 69.0 87.2 207.2 248.4 66.6 32.8 38.6 88.8 114.2 32.9 98.5 142.2 107.1 61.4 40.4 81.5 39.9 274.7 105.5 34.3 21.3 58.9 52.0 33.1 82.9 117.4 189.6 164.6 44.4 16.3 254.9 156.6 140.6 121.8 14.2 164.9 141.4 234.0 75.6 52.7 40.6 53.4 52.7 39.6 26.6 68.2 53.3 181.0 50.5 17.6 91.7 49.3 115.9 56.6 83.0 274.5 24.3 120.5 61.2 83.6 44.3 67.3 43.6 31.6 50.9 39.0 43.5 48.8 38.4 39.5 42.4 52.9 211.4 41.3 25.2 21.5 61.9 69.8 8.8 9.7 9.3 11.9 8.5 10.1 12.0 9.8 11.2 10.2 9.5 13.1 98.1 28.9 36.4 13.4 86.4 27.0 33.4 17.3 21.6 4.5 11.9 11.0 8.5 48.6 34.4 31.3 6.2 40.5 98.3 33.4 5.9 23.6 1.2 31.5 31.0 53.1 27.0 248.9 10.5 19.8 23.9 29.0 29.0 53.9 10.1 24.0 48.5 73.6 44.4 11.8 14.3 43.0 12.2 88.5 18.1 3.4 33.8 71.7 26.6 19.7 56.0 11.6 82.4 37.2 34.1 20.6 24.6 32.4 74.0 32.9 19.3 26.0 26.0 10.4 39.5 13.9 46.6 21.0 26.7 68.4 35.5 11.1 81.3 13.2 73.8 36.7 LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.2;Endothelial cells: 144.6;Erythroid cells: 103.7;Hepatic stellate cells: 167.4;Kupffer cells: 65.0;Microglial cells: 64.6" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Cell line enhanced" "Detected in some" "HEL: 71.8;HL-60: 72.7;K-562: 60.9;NB-4: 27.3;THP-1: 81.6;U-937: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Enhanced Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" 15.0 5.9 14.9 11.4 13.0 27.7 12.5 14.2 16.6 8.4 13.4 5.0 4.6 6.5 0.7 6.8 8.3 5.4 4.4 14.7 16.0 13.1 2.3 18.2 19.4 19.9 16.3 3.5 2.6 2.3 8.6 6.5 18.5 5.7 1.5 0.6 5.3 2.4 23.4 4.9 6.6 4.8 18.7 19.0 3.9 1.7 19.0 1.8 12.3 4.6 8.4 5.8 7.3 13.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 2.2 1.3 12.8 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 71.8 0.0 0.0 0.3 72.7 18.5 0.0 0.0 0.0 0.0 0.0 10.2 0.0 60.9 0.0 0.0 0.3 5.1 27.3 0.9 0.0 0.0 15.3 0.8 0.2 0.0 0.8 4.3 0.0 0.3 0.5 0.1 0.2 0.0 81.6 0.9 0.0 0.2 1.7 0.0 0.0 0.2 0.6 4.7 29.2 0.3 0.6 0.5 1.5 0.0 1.4 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 1.7 0.1 0.0 0.2 14.9 13.0 14.2 16.6 14.7 16.0 19.9 16.3 18.5 18.7 19.0 13.3 109.2 3.2 7.1 8.5 6.6 8.4 7.9 8.0 0.6 1.6 2.8 9.5 2.8 8.6 1.7 5.5 2.1 0.4 1.0 0.8 0.0 3.0 0.5 40.5 11.0 144.6 0.0 103.7 1.3 2.0 3.2 9.8 0.0 39.6 7.6 0.9 167.4 1.7 39.1 0.0 3.8 0.2 2.0 65.0 56.8 1.2 4.1 54.1 10.6 64.6 47.5 1.1 4.1 5.0 1.0 1.0 1.9 0.0 3.0 5.4 0.0 8.8 5.0 2.6 0.0 17.3 3.6 0.3 7.9 0.8 6.0 21.5 1.9 12.4 0.5 25.1 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 184.8;Collecting duct cells: 125.0;Gastric mucus-secreting cells: 111.1;Glandular and luminal cells: 107.7;Microglial cells: 346.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 55.5;RPTEC TERT1: 71.2;RT4: 119.6;TIME: 53.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" 16.0 0.9 7.3 7.3 7.2 1.4 12.3 8.5 7.3 21.3 2.4 24.9 19.8 17.3 4.4 13.5 23.4 8.3 13.0 4.9 6.3 41.3 1.4 25.5 1.5 9.1 7.2 2.3 23.3 1.7 4.2 17.4 8.9 6.9 30.0 1.8 8.8 8.0 4.3 2.6 10.2 8.0 4.1 6.2 73.3 3.0 8.1 2.0 5.7 12.0 5.3 30.4 7.5 6.3 25.8 0.7 0.9 0.2 3.7 2.7 1.1 3.7 4.2 1.1 2.2 10.7 26.1 0.9 39.1 0.6 5.5 13.4 10.2 15.7 3.1 1.4 16.6 16.7 7.6 1.1 0.4 0.3 5.1 5.7 2.2 1.0 12.1 12.0 55.5 1.4 13.0 1.8 10.3 9.8 0.9 0.4 1.7 13.5 6.6 9.8 13.1 0.3 71.2 119.6 1.0 3.1 1.3 6.7 0.3 1.5 7.1 1.1 53.4 9.7 6.6 2.5 16.9 1.4 0.7 0.9 4.8 1.0 1.6 0.9 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.3 0.4 0.5 1.6 0.1 0.0 7.3 7.2 8.5 7.3 4.9 6.3 9.1 7.2 8.9 4.1 8.1 6.3 80.2 60.9 184.8 16.0 0.6 2.2 33.3 29.4 10.2 0.0 1.2 0.9 11.4 2.8 69.6 125.0 0.0 1.1 0.1 25.5 52.8 1.6 10.4 71.9 5.8 70.5 19.9 7.4 10.3 75.4 0.2 4.8 111.1 107.7 9.5 0.8 69.3 0.2 0.0 0.0 9.1 29.0 20.3 0.6 1.9 3.2 0.3 2.6 1.8 346.6 1.0 0.0 0.0 6.0 13.8 49.8 19.3 0.0 0.3 13.9 6.2 0.7 53.2 0.1 0.0 1.4 5.7 3.0 1.2 39.4 1.4 0.4 1.3 0.5 53.9 45.4 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 36.0;breast: 26.1;heart muscle: 24.9" "Group enriched" "Detected in some" 9 "Adipocytes: 63.5;Endothelial cells: 41.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Cell line enriched" "Detected in some" 14 "HeLa: 25.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" 36.0 0.5 0.0 4.7 0.0 0.0 26.1 0.0 0.1 8.0 0.0 4.7 1.6 5.5 1.1 3.7 9.0 5.7 24.9 0.0 0.0 0.2 0.1 1.4 6.6 0.0 0.0 1.0 1.5 1.2 0.5 0.1 0.0 2.6 2.4 0.0 4.9 1.9 8.3 6.6 5.1 10.6 0.0 10.8 3.0 1.1 0.0 3.0 1.9 17.1 5.3 7.7 7.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.1 0.0 0.0 1.8 0.1 0.5 0.0 0.1 0.0 0.0 0.1 0.1 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 4.3 2.7 0.0 0.0 1.7 0.5 0.0 0.3 0.0 0.0 17.5 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.5 0.0 0.0 1.0 0.3 4.1 0.0 0.0 1.2 0.0 0.4 0.6 2.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 41.3 0.0 0.0 0.7 0.0 0.3 4.8 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 1.0 0.0 0.1 0.3 1.8 0.1 1.5 0.3 0.0 0.0 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 NOD1 "CARD4, CLR7.1, NLRC1" ENSG00000106100 "Nucleotide binding oligomerization domain containing 1" Q9Y239 7 30424527-30478784 "Human disease related genes, Predicted intracellular proteins" "Apoptosis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Microglial cells: 26.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074367 Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "HPA074367: AB_2686683" "unprognostic (2.58e-1)" "unprognostic (1.56e-2)" "unprognostic (9.73e-2)" "unprognostic (8.09e-3)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-3)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (2.74e-1)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.68e-4)" "unprognostic (6.62e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.95e-4)" "unprognostic (2.64e-1)" 10.6 2.9 3.0 8.8 3.2 6.8 9.5 2.5 2.6 5.3 4.6 5.3 2.2 6.1 2.6 4.7 6.5 5.4 7.3 2.4 3.2 3.9 2.2 11.9 6.1 7.6 4.9 10.3 1.8 2.7 2.9 12.2 4.7 4.0 4.3 0.6 6.2 3.2 4.0 5.9 5.4 7.3 3.6 11.1 4.8 1.9 5.6 3.5 10.8 4.0 5.0 7.3 5.0 2.8 4.8 2.5 3.5 10.5 2.2 10.3 5.3 3.3 2.3 5.5 7.0 2.2 5.7 6.9 3.8 4.2 6.1 11.2 3.5 5.8 3.7 3.6 3.0 9.7 7.7 2.2 2.8 4.3 7.0 9.6 2.5 3.5 3.0 4.9 18.3 10.1 5.2 2.4 5.0 2.8 6.2 7.7 4.1 5.3 4.5 7.4 4.0 6.3 1.8 3.8 0.6 12.4 4.2 10.7 3.7 4.8 3.6 9.6 7.7 4.8 7.6 6.0 4.5 2.2 8.0 0.3 3.5 15.1 5.1 13.7 3.7 13.5 8.1 5.0 8.9 7.5 5.5 5.3 3.3 10.9 4.9 4.0 2.8 8.5 6.6 8.0 4.8 2.6 3.0 3.2 2.5 2.6 2.4 3.2 7.6 4.9 4.7 3.6 5.6 2.8 19.3 3.2 15.1 7.2 6.6 0.8 0.5 1.0 5.2 2.4 2.9 2.9 4.9 1.5 5.0 5.5 0.0 5.0 6.7 4.5 0.0 1.3 0.2 4.4 1.7 12.0 0.0 3.4 5.3 2.1 2.3 8.2 1.1 4.6 2.5 7.8 13.6 1.3 4.6 0.0 1.4 5.5 2.0 3.1 3.7 0.0 0.6 4.3 5.4 26.2 4.0 0.6 6.2 2.5 1.1 1.7 1.7 1.9 3.1 0.2 1.6 0.5 2.9 0.2 0.0 2.5 5.6 0.0 0.6 5.4 1.8 1.5 5.3 1.0 5.6 0.8 NOS3 "ECNOS, eNOS" ENSG00000164867 "Nitric oxide synthase 3" P29474 7 150991017-151014588 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 62.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.4;Early spermatids: 81.9;Endothelial cells: 32.6;Hepatic stellate cells: 29.3;Late spermatids: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "BEWO: 23.1;HUVEC TERT2: 44.7;K-562: 16.6;TIME: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002168 Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002168: AB_564072" "unprognostic (6.53e-2)" "unprognostic (3.36e-1)" "unprognostic (1.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (6.97e-2)" "unprognostic (2.56e-1)" "unprognostic (9.40e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" 19.3 6.3 8.4 5.8 6.8 0.8 13.2 5.7 6.7 7.3 3.4 5.9 2.6 9.7 0.4 5.8 8.1 4.7 20.6 5.7 6.1 24.2 4.3 11.2 2.7 9.2 7.7 3.2 2.9 1.2 7.2 4.8 8.6 7.6 1.2 0.8 4.4 1.7 3.9 4.2 6.7 3.7 7.5 62.4 5.4 7.2 11.0 0.6 9.1 3.5 1.2 9.7 7.4 6.0 0.4 0.1 1.3 4.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.3 2.2 0.4 2.1 0.0 0.2 0.7 0.0 0.1 0.0 0.0 0.4 2.2 0.3 6.4 0.6 0.5 10.4 0.1 0.2 0.0 0.0 0.1 44.7 5.1 16.6 3.6 0.0 0.0 0.2 0.5 1.7 0.7 0.1 3.0 0.0 1.8 0.0 0.3 0.5 0.4 0.2 1.4 0.0 0.4 0.1 1.4 82.5 0.2 0.7 0.4 0.1 2.4 8.9 2.2 0.0 7.5 0.0 0.2 0.1 0.1 1.1 0.2 0.7 0.3 1.7 0.9 0.2 0.5 2.3 0.9 0.3 0.2 0.2 0.2 2.1 0.5 8.4 6.8 5.7 6.7 5.7 6.1 9.2 7.7 8.6 7.5 11.0 6.0 20.4 9.6 2.2 0.3 0.7 0.9 0.1 0.1 0.0 0.2 0.2 0.3 3.1 0.0 0.7 0.0 0.0 0.2 0.7 0.1 0.0 1.0 81.9 4.9 0.7 32.6 0.0 0.0 0.2 0.0 0.1 2.9 0.5 3.2 5.7 0.7 29.3 0.7 0.4 0.0 0.2 0.4 0.0 0.6 0.5 29.3 0.9 0.4 0.0 7.5 0.0 0.3 0.0 0.0 0.0 0.8 0.0 1.2 1.5 0.4 0.1 0.2 2.2 0.3 0.0 0.6 2.6 6.9 5.3 0.2 0.6 3.6 1.6 0.9 0.1 0.9 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.9;parathyroid gland: 81.0" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Endothelial cells: 115.3;Excitatory neurons: 71.9;Extravillous trophoblasts: 64.7;Hepatic stellate cells: 160.3" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 7 "granulocytes: 2.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "ASC diff: 140.0;ASC TERT1: 107.6;fHDF/TERT166: 147.5;JURKAT: 134.8;REH: 196.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 14: REH - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" 66.4 5.1 49.1 6.4 44.9 0.5 64.2 46.0 80.8 16.2 17.0 21.3 3.7 9.4 4.0 8.2 13.6 11.2 19.7 98.9 27.7 8.2 4.4 15.6 9.6 30.4 29.9 4.7 2.9 81.0 12.3 42.1 32.5 10.1 4.7 23.4 8.7 7.4 17.3 18.8 10.8 10.5 22.1 15.7 10.3 0.6 60.1 3.6 9.4 16.1 3.5 13.8 17.0 45.9 16.7 0.6 1.4 0.1 140.0 107.6 19.1 2.6 0.0 11.8 16.1 0.2 0.1 0.0 2.5 147.5 25.0 0.5 43.3 0.0 11.4 26.1 21.2 13.7 0.0 0.0 0.0 58.0 43.7 17.3 0.0 10.5 0.0 0.1 57.4 134.8 0.2 0.6 42.5 0.1 89.7 2.6 0.1 0.0 0.0 196.3 47.7 0.4 0.2 0.2 24.9 9.2 0.0 0.8 13.9 0.2 0.4 16.4 12.1 56.4 1.6 21.4 36.5 0.1 2.2 0.9 85.8 0.2 8.9 0.0 0.1 0.0 0.1 0.1 2.6 0.3 0.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.2 0.0 0.1 49.1 44.9 46.0 80.8 98.9 27.7 30.4 29.9 32.5 22.1 60.1 45.9 262.9 0.0 1.3 7.2 1.6 10.5 0.1 0.0 1.2 6.7 1.4 2.4 2.5 1.5 0.0 0.0 2.1 1.5 1.0 0.0 0.0 0.1 0.1 0.0 0.1 115.3 0.0 0.0 71.9 0.5 64.7 15.9 0.0 0.1 0.0 0.0 160.3 0.9 1.8 3.3 3.0 0.0 0.0 4.1 21.5 0.4 0.9 1.4 16.0 8.4 0.5 4.5 0.0 13.6 8.3 0.2 0.0 0.0 1.4 0.4 0.0 0.0 0.0 20.2 0.0 4.4 18.3 0.4 0.3 0.6 11.2 1.4 1.9 0.1 0.0 0.7 NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 366.0;Endothelial cells: 174.4;Hepatic stellate cells: 184.6;Sertoli cells: 282.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 48.6" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.3" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.3" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 444.6;hTERT-RPE1: 371.6;TIME: 369.5;U-87 MG: 425.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved "Secreted in other tissues" NA NA 780000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" 125.2 42.3 9.3 43.3 9.4 3.7 62.2 0.0 26.0 36.9 13.3 26.6 21.3 51.6 35.7 19.7 34.5 54.1 80.8 48.6 9.1 52.7 53.1 63.7 23.7 4.0 3.9 43.0 33.0 24.4 9.0 133.7 2.1 21.3 23.6 11.6 19.3 38.4 55.9 22.1 21.0 55.9 5.7 66.7 18.6 12.9 13.4 18.2 49.7 46.6 12.4 35.3 20.0 10.7 57.4 217.8 11.1 1.1 204.8 224.7 1.3 224.4 216.2 109.6 118.2 28.9 132.4 1.1 26.6 444.6 116.8 15.8 13.8 65.2 89.3 0.7 11.2 0.6 24.5 48.7 74.3 20.8 1.6 277.3 11.2 261.7 116.8 371.6 304.0 1.4 0.7 1.4 221.3 96.8 1.4 3.9 5.5 11.9 204.2 9.6 24.8 1.2 109.7 1.3 5.1 2.7 23.0 17.5 0.9 9.2 1.0 3.3 369.5 156.4 36.9 193.0 153.8 0.7 1.1 0.7 425.2 26.4 143.5 0.4 2.5 0.5 0.6 0.4 1.0 0.7 0.7 0.6 2.3 0.6 0.6 0.6 0.4 1.2 0.3 39.3 0.6 0.9 9.3 9.4 0.0 26.0 48.6 9.1 4.0 3.9 2.1 5.7 13.4 10.7 366.0 0.0 20.2 80.3 4.3 15.7 10.6 5.5 7.4 10.5 4.2 5.5 67.6 28.6 13.0 18.4 4.2 61.5 29.4 0.6 1.9 57.9 1.3 11.3 116.9 174.4 4.2 3.2 105.4 18.9 13.4 58.5 6.6 11.0 7.6 62.3 184.6 12.5 135.4 0.0 14.4 1.8 16.2 62.7 33.3 5.5 42.3 46.0 12.4 78.7 5.8 3.4 0.0 11.6 2.3 15.4 0.0 21.1 1.6 4.1 3.0 59.8 5.4 0.9 282.7 13.1 117.9 0.2 1.3 2.7 10.5 67.2 3.8 61.1 1.5 3.3 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 197.0" "Group enriched" "Detected in many" 6 "Adipocytes: 114.9;Endothelial cells: 58.5;Enteroendocrine cells: 34.4;Excitatory neurons: 70.1;Hepatic stellate cells: 118.2;Inhibitory neurons: 35.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 75.1;basal ganglia: 84.7;cerebral cortex: 102.1;hippocampal formation: 84.4;white matter: 48.3" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Cell line enriched" "Detected in some" 8 "HeLa: 513.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "amygdala: 83.5;basal ganglia: 146.9;cerebral cortex: 90.5;hippocampal formation: 94.0" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" 89.2 44.1 75.1 5.1 84.7 4.7 83.6 0.0 102.1 38.1 0.0 34.6 6.0 27.2 8.3 18.6 39.3 22.7 41.1 84.4 7.0 32.5 19.4 12.6 6.7 6.4 5.1 11.6 6.9 5.5 11.8 12.0 10.1 20.7 8.9 3.0 9.2 10.7 16.8 18.1 18.7 18.5 0.0 197.0 17.1 7.4 17.9 3.8 24.1 28.9 3.5 28.8 27.1 48.3 0.3 0.2 0.7 0.2 0.2 0.1 0.3 0.1 0.2 0.2 0.4 0.4 2.5 0.8 12.2 0.2 1.9 0.2 0.9 0.1 0.1 0.1 0.1 0.0 513.6 0.8 0.9 0.0 7.8 0.1 1.1 2.7 20.5 1.1 11.3 0.5 0.8 0.9 0.1 0.0 0.2 0.2 7.4 0.2 14.0 0.0 0.2 1.4 0.1 0.3 44.5 2.4 0.4 0.2 2.2 0.7 0.3 0.1 65.2 0.1 9.4 3.5 0.4 0.4 0.2 0.1 3.9 0.1 0.6 0.0 0.6 0.0 7.3 0.8 4.2 2.8 4.3 4.3 1.0 1.8 2.7 2.3 0.1 0.0 0.4 0.0 1.8 1.5 75.1 84.7 0.0 102.1 84.4 7.0 6.4 5.1 10.1 0.0 17.9 48.3 114.9 0.0 0.5 2.0 0.7 2.5 0.1 0.0 0.0 4.9 0.6 1.0 7.8 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.6 0.0 0.1 58.5 34.4 5.3 70.1 0.0 0.3 2.1 0.0 0.1 1.3 0.1 118.2 2.1 0.5 1.7 35.6 1.2 0.0 9.4 8.2 2.5 0.3 4.9 1.8 11.2 0.0 0.0 0.0 9.0 5.7 0.1 0.0 0.4 1.5 0.1 0.0 0.1 0.0 0.4 0.0 1.8 6.6 4.8 2.5 0.5 2.8 0.0 0.6 0.2 0.1 0.3 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PML "MYL, RNF71, TRIM19" ENSG00000140464 "PML nuclear body scaffold" P29590 15 73994673-74047827 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Biological rhythms, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Transferase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008312, CAB010194, CAB016304" Supported Enhanced "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "CAB010194: AB_2166848, CAB016304: AB_628162, HPA008312: AB_1079643" "prognostic favorable (3.24e-4)" "unprognostic (4.83e-2)" "unprognostic (5.76e-2)" "unprognostic (1.58e-3)" "unprognostic (7.53e-3)" "unprognostic (1.58e-1)" "unprognostic (2.35e-2)" "unprognostic (5.30e-3)" "unprognostic (4.54e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-2)" "prognostic unfavorable (6.27e-8)" "unprognostic (1.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.99e-2)" 84.4 29.4 14.4 25.6 13.8 38.1 77.0 11.8 16.4 53.7 11.6 46.7 18.4 47.1 7.5 38.3 44.6 21.6 39.3 13.8 13.1 35.4 25.4 75.2 25.6 18.2 13.8 37.5 20.3 8.3 26.8 23.7 14.8 41.5 8.5 3.9 44.2 17.2 22.5 47.4 39.0 19.5 14.6 48.6 35.3 11.3 15.2 17.0 48.1 7.9 15.2 42.7 44.5 13.1 37.2 13.8 11.8 11.4 30.2 43.2 40.6 18.5 31.6 55.9 63.3 14.6 64.2 16.4 63.7 31.6 53.3 66.6 16.3 37.1 7.6 58.0 25.1 35.8 21.3 16.3 36.9 33.9 31.1 83.7 24.8 37.5 19.2 39.3 38.3 26.1 30.6 28.3 32.7 17.3 28.3 52.6 12.8 7.7 25.0 21.6 13.4 30.8 60.3 59.5 10.1 11.1 29.7 16.3 44.8 10.3 12.8 28.7 66.1 56.6 15.5 28.5 38.1 29.4 20.0 8.0 38.9 42.2 18.2 7.4 14.7 23.4 13.0 20.2 9.8 12.4 10.4 14.1 14.5 10.2 8.2 8.5 12.0 14.5 22.6 9.2 14.3 10.1 14.4 13.8 11.8 16.4 13.8 13.1 18.2 13.8 14.8 14.6 15.2 13.1 127.8 16.0 12.2 8.8 24.9 22.9 14.3 30.4 37.5 8.1 13.5 12.8 10.0 5.7 16.7 5.5 2.1 9.4 18.8 13.1 7.9 25.8 3.4 16.0 16.7 48.0 14.3 29.3 4.7 19.1 15.0 20.7 58.1 26.0 12.0 11.5 32.2 11.3 30.8 8.4 4.8 14.3 14.2 20.1 18.5 4.0 27.7 19.6 7.2 7.5 24.6 8.5 20.6 4.5 6.0 62.8 15.5 24.0 21.6 26.2 22.8 10.4 18.3 5.4 39.5 7.7 20.4 1.1 4.0 27.1 19.6 4.9 20.4 16.8 12.1 26.0 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 PRKD2 "DKFZP586E0820, HSPC187, PKD2" ENSG00000105287 "Protein kinase D2" Q9BZL6 19 46674275-46717127 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Cell adhesion, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/84: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021490, HPA056727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA021490: AB_1855708, HPA056727: AB_2683217" "unprognostic (3.01e-2)" "unprognostic (1.22e-2)" "unprognostic (1.23e-3)" "unprognostic (7.06e-2)" "unprognostic (8.91e-2)" "unprognostic (1.99e-2)" "unprognostic (8.79e-3)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (4.21e-3)" "unprognostic (8.89e-2)" "unprognostic (2.74e-1)" "unprognostic (3.45e-3)" "unprognostic (1.04e-2)" "unprognostic (7.19e-2)" "unprognostic (4.34e-2)" "prognostic favorable (9.15e-4)" 29.0 11.5 7.2 23.6 7.3 29.4 29.3 5.4 7.7 26.6 12.5 20.3 17.1 21.8 4.7 27.5 24.1 11.2 13.8 6.1 6.0 19.2 13.8 34.3 31.1 10.0 6.3 21.8 19.1 8.3 24.0 11.1 6.8 23.9 7.1 4.4 24.7 10.0 8.0 46.8 29.9 6.0 6.0 54.3 20.3 6.6 7.7 25.6 28.9 4.8 21.2 19.5 26.9 6.6 19.6 34.5 12.8 16.6 7.3 6.4 15.1 11.5 13.2 19.6 19.7 19.7 21.0 22.3 16.3 13.2 13.2 27.5 9.5 26.0 5.9 19.8 17.5 25.9 11.5 10.2 12.8 21.2 34.7 11.0 15.8 12.7 9.8 12.8 30.1 21.5 14.6 35.4 7.0 23.8 32.7 53.1 9.7 27.4 17.4 25.8 5.8 37.5 11.4 32.7 7.7 22.4 18.8 18.8 4.6 10.6 11.6 7.5 17.6 8.7 18.8 7.1 10.0 31.8 149.1 13.5 8.5 17.7 11.0 0.6 0.7 2.6 3.9 0.7 3.3 4.3 3.9 4.3 0.3 4.1 3.3 3.3 5.3 2.2 0.5 0.0 2.9 1.5 7.2 7.3 5.4 7.7 6.1 6.0 10.0 6.3 6.8 6.0 7.7 6.6 37.8 9.6 9.9 5.9 46.5 22.0 32.0 13.2 22.8 6.4 13.9 11.3 17.2 12.8 13.0 9.2 0.0 13.8 17.5 43.6 7.9 18.6 1.2 15.3 6.7 37.2 21.6 4.0 6.5 28.2 13.8 9.6 23.4 15.0 14.5 14.1 37.1 8.5 9.0 1.7 2.8 21.7 4.1 12.3 11.4 3.1 11.8 8.3 12.4 11.2 9.3 6.5 42.2 4.0 3.1 29.5 35.1 6.8 47.0 22.9 34.1 9.3 15.6 4.4 13.1 6.1 7.6 2.9 17.9 21.2 26.7 29.7 31.9 6.6 15.3 30.2 PRR29 "C17orf72, DKFZp761M2312, FLJ11724" ENSG00000224383 "Proline rich 29" P0C7W0 17 63998351-64004305 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 58.2" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 57.4;Respiratory ciliated cells: 89.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.5;REH: 3.7;TIME: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051264 Uncertain Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA051264: " "unprognostic (2.05e-2)" "unprognostic (6.46e-2)" "unprognostic (2.87e-2)" "unprognostic (2.92e-3)" "unprognostic (4.71e-3)" "unprognostic (3.22e-2)" "unprognostic (3.84e-1)" "unprognostic (3.95e-2)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.30e-3)" "unprognostic (6.48e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.98e-3)" 2.0 0.3 3.2 0.5 2.5 0.3 2.2 1.8 1.2 6.1 12.7 0.4 0.2 0.6 0.3 0.2 58.2 0.7 1.5 4.1 4.2 1.9 0.2 10.4 0.4 12.7 16.0 0.6 0.3 0.9 10.7 0.3 7.3 0.7 0.0 0.0 0.5 0.6 0.6 0.4 0.7 0.2 9.0 5.7 0.3 13.9 4.0 0.2 4.7 0.0 0.3 0.8 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 3.5 0.0 0.3 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.0 0.5 0.0 0.0 0.0 1.3 0.0 0.1 0.7 0.1 3.7 0.0 1.5 0.3 0.0 0.2 1.0 0.0 0.1 0.2 0.5 0.5 0.0 2.8 0.1 1.1 0.4 0.1 0.4 0.1 0.2 0.4 0.1 0.0 0.9 0.2 0.0 0.4 0.5 0.1 0.1 0.4 0.2 0.1 0.2 0.7 0.4 0.2 0.2 0.4 0.0 0.2 0.3 3.2 2.5 1.8 1.2 4.1 4.2 12.7 16.0 7.3 9.0 4.0 3.9 3.3 0.0 2.8 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.2 1.5 9.9 3.7 0.0 0.0 0.7 0.0 0.0 0.1 12.4 57.4 0.5 2.1 0.0 0.0 0.5 0.0 0.1 0.6 0.0 1.1 0.0 1.6 1.8 0.5 0.3 0.0 0.4 0.0 0.0 0.0 0.0 10.5 0.0 0.9 0.0 1.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 2.0 0.0 0.0 0.1 89.6 0.0 0.0 0.3 0.3 18.1 1.4 0.0 0.0 0.3 0.7 3.5 0.0 0.1 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 60.5 30.1 24.2 43.9 26.6 69.9 50.3 29.2 31.6 40.9 25.9 48.9 18.9 38.6 18.6 38.5 39.6 40.2 39.0 25.1 27.3 36.1 30.9 65.0 27.5 28.5 27.8 34.6 20.1 21.0 21.9 74.7 30.5 26.4 27.7 30.9 23.8 33.2 24.6 36.9 29.7 40.2 26.7 52.7 27.1 30.1 32.7 33.9 31.0 44.5 27.5 46.7 39.6 30.2 72.4 43.5 100.6 51.8 69.1 71.7 54.2 73.3 93.0 56.6 80.0 21.6 109.9 8.6 23.2 86.3 123.6 50.2 34.2 73.4 113.3 21.2 19.2 44.9 44.2 88.4 67.7 25.8 28.8 59.0 80.3 123.2 157.6 101.0 121.6 2.1 54.9 12.2 182.6 49.4 3.6 71.9 81.7 97.6 49.2 15.1 80.6 4.5 97.6 38.5 12.5 66.6 90.4 81.5 73.4 172.2 39.5 93.9 89.3 121.4 73.1 45.0 141.3 12.6 7.4 22.2 71.6 65.9 215.7 3.6 4.1 6.8 3.1 2.8 1.3 2.3 1.1 2.6 3.8 1.0 0.6 3.3 9.5 13.3 5.3 0.3 1.6 2.7 24.2 26.6 29.2 31.6 25.1 27.3 28.5 27.8 30.5 26.7 32.7 30.2 139.3 70.5 56.2 30.0 18.2 68.8 60.0 55.9 23.9 16.7 40.9 26.3 41.3 28.6 46.4 20.2 8.4 40.0 89.0 31.2 3.9 42.1 3.5 43.9 62.4 114.4 12.1 16.6 65.8 39.6 58.7 54.6 21.4 87.2 14.5 21.7 119.2 24.6 50.1 35.3 58.0 21.7 28.5 82.0 121.3 6.7 46.6 96.1 35.6 93.7 54.9 66.9 163.7 70.4 67.3 75.0 21.4 47.0 17.6 62.0 10.9 19.2 23.2 15.2 65.7 127.9 66.8 51.2 71.4 29.8 101.4 72.1 27.3 24.4 23.3 104.8 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 152.1;parathyroid gland: 387.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 504.6;Inhibitory neurons: 193.4;Microglial cells: 138.7;Oligodendrocytes: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 21.1;HUVEC TERT2: 45.0;SCLC-21H: 34.1;TIME: 25.8;U-698: 37.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" 21.0 12.7 30.7 7.0 82.9 0.9 16.4 76.1 58.5 8.9 2.9 9.5 7.5 8.8 4.8 13.9 8.3 16.8 16.8 45.7 46.9 16.7 21.8 37.5 14.3 115.3 71.8 6.5 20.1 387.8 7.4 67.2 107.1 5.1 11.0 4.2 7.6 5.7 5.1 9.2 8.3 12.1 82.0 50.9 7.0 6.4 59.8 15.7 11.7 11.1 10.7 9.3 11.9 152.1 2.8 0.0 4.6 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 5.5 1.4 21.1 1.1 0.3 0.7 13.0 2.8 1.9 0.0 0.0 4.2 0.3 0.0 5.4 0.1 0.0 0.1 0.5 2.4 1.3 0.7 0.7 45.0 5.9 4.8 0.1 0.0 1.2 3.0 0.1 3.6 5.4 4.0 5.2 0.0 7.4 4.2 1.9 34.1 9.0 0.5 6.0 0.1 0.7 3.0 0.1 25.8 0.0 1.0 0.4 1.1 10.9 2.5 37.4 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 82.9 76.1 58.5 45.7 46.9 115.3 71.8 107.1 82.0 59.8 152.1 125.5 9.6 16.5 13.4 3.1 11.0 4.2 2.4 86.0 30.6 8.8 5.5 10.0 15.7 3.8 0.0 0.0 0.3 0.6 16.0 1.9 6.5 61.5 3.3 1.2 70.1 7.2 0.4 504.6 7.0 0.1 5.3 16.3 10.8 8.2 0.1 86.0 6.3 0.2 23.5 193.4 18.3 2.0 3.1 2.0 65.2 1.8 0.9 7.2 138.7 0.0 0.6 0.0 28.1 640.8 5.0 20.3 4.9 12.9 3.0 18.1 0.3 0.5 1.6 85.5 1.4 21.5 1.2 1.6 19.8 11.2 0.3 2.4 1.9 10.1 4.4 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RBMS2 SCR3 ENSG00000076067 "RNA binding motif single stranded interacting protein 2" Q15434 12 56521820-56596193 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039225, HPA058784" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA039225: AB_10963056, HPA058784: AB_2683819" "unprognostic (1.35e-1)" "unprognostic (5.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.29e-2)" "unprognostic (9.09e-2)" "unprognostic (3.19e-3)" "unprognostic (4.78e-2)" "unprognostic (1.89e-2)" "unprognostic (7.01e-2)" "unprognostic (2.80e-1)" "unprognostic (2.86e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.22e-4)" "unprognostic (2.67e-2)" "unprognostic (4.73e-2)" "unprognostic (4.06e-3)" "unprognostic (2.63e-2)" 19.4 7.1 12.5 5.7 11.5 3.6 17.4 9.3 13.1 14.7 15.1 12.9 4.7 13.7 9.3 8.2 13.7 9.5 15.6 9.2 10.0 14.7 3.4 37.3 3.2 14.5 11.7 12.6 7.0 8.6 6.1 23.5 13.4 11.2 8.8 6.0 10.1 8.7 8.4 8.3 9.0 12.1 9.8 10.5 8.5 4.3 15.2 3.5 18.3 10.8 3.9 10.3 13.9 11.7 28.8 24.3 10.5 14.9 23.7 22.7 9.3 34.8 37.0 26.9 23.9 18.7 50.2 0.2 42.1 36.6 11.1 20.4 7.8 57.8 30.1 8.3 6.7 3.7 19.0 4.8 15.4 3.8 6.5 20.9 13.9 28.1 33.5 31.4 51.1 6.1 1.8 6.5 47.0 3.7 4.1 4.9 6.2 0.0 7.5 2.4 11.5 0.3 34.1 6.4 0.8 6.9 39.6 14.9 5.1 22.2 16.0 6.3 78.2 16.7 35.8 9.5 8.4 6.1 2.5 1.7 6.1 0.9 23.6 0.6 4.7 1.6 0.8 1.3 0.9 0.3 0.3 1.2 2.7 0.5 0.9 0.6 1.6 1.0 0.3 0.6 0.5 0.8 12.5 11.5 9.3 13.1 9.2 10.0 14.5 11.7 13.4 9.8 15.2 11.7 74.4 41.7 20.5 34.6 1.5 3.7 9.7 6.8 11.4 4.2 11.4 9.4 7.9 12.8 14.2 12.9 10.4 19.8 7.0 19.7 1.9 23.6 12.6 16.4 16.9 47.9 5.4 3.2 7.2 16.9 38.5 16.9 6.1 21.8 8.2 10.4 52.1 1.0 10.5 8.4 10.0 5.9 4.1 22.7 5.5 24.2 17.4 11.2 0.0 53.4 6.2 5.4 4.1 30.7 9.6 37.8 11.5 24.8 0.8 13.4 1.6 13.4 6.8 1.7 26.3 11.2 15.5 0.9 1.8 5.4 2.0 23.7 2.5 8.7 7.0 17.3 RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Endothelial cells: 23.6;Hofbauer cells: 30.0;Pancreatic endocrine cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.3;intermediate monocyte: 15.6;memory B-cell: 15.8;myeloid DC: 10.2;naive B-cell: 9.4;neutrophil: 6.6;non-classical monocyte: 15.1;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" 44.4 28.1 27.6 23.4 30.6 27.2 37.7 26.4 38.6 39.9 7.5 36.0 8.8 45.2 6.0 18.5 36.2 21.5 53.6 33.6 16.3 67.6 16.7 55.8 20.8 26.6 17.1 33.2 30.1 20.6 26.5 29.8 25.4 30.6 7.4 43.8 22.8 20.2 34.9 21.4 32.7 25.2 12.3 61.2 25.9 18.6 21.5 10.8 36.4 22.3 17.5 37.1 30.4 18.6 44.0 36.6 16.1 25.3 40.0 35.7 35.7 45.7 44.9 51.6 43.0 75.7 31.5 6.0 62.4 78.8 26.0 24.4 32.7 41.3 33.2 19.3 17.0 57.9 53.6 17.4 44.7 4.6 28.0 35.5 18.8 69.7 47.1 36.8 55.2 10.2 6.5 6.4 38.7 47.7 13.8 14.4 4.4 8.5 29.1 46.8 29.0 31.2 39.0 22.1 12.1 31.9 85.1 13.8 28.6 15.9 30.2 10.7 96.8 58.3 34.2 49.8 32.2 9.0 6.8 17.8 38.8 11.1 31.7 0.1 11.2 9.3 1.2 15.6 1.8 15.8 1.0 0.5 10.2 9.4 0.7 0.7 6.6 1.7 15.1 14.4 0.8 6.0 27.6 30.6 26.4 38.6 33.6 16.3 26.6 17.1 25.4 12.3 21.5 18.6 49.2 16.0 16.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 12.1 8.8 0.0 0.0 1.8 7.3 0.0 0.8 3.7 0.0 0.0 15.8 0.0 9.3 17.9 23.6 0.0 0.0 0.0 12.5 1.3 6.9 0.0 18.5 10.1 7.9 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 37.0 0.0 0.0 2.3 0.0 0.0 5.8 2.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 2.1 2.3 16.6 0.0 0.0 SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 430.3;Hepatic stellate cells: 286.3;Late spermatids: 740.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 355.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 355.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 398.1;TIME: 251.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" 66.7 54.2 42.6 44.6 63.3 65.5 57.6 75.4 60.7 39.5 36.3 19.5 21.8 24.6 28.2 31.5 27.3 34.3 50.2 49.5 57.5 42.0 25.3 66.9 49.7 64.0 63.0 20.7 30.8 25.1 27.9 76.7 54.6 18.3 19.8 19.0 35.0 16.8 94.1 20.5 21.7 27.1 46.2 49.9 31.7 51.9 63.6 24.1 41.6 54.7 46.2 26.0 20.6 50.9 55.0 45.4 65.6 105.0 27.4 36.3 24.1 47.4 42.0 57.8 49.5 55.7 39.6 143.1 93.3 65.0 71.1 26.3 36.0 47.8 72.6 27.3 50.1 81.1 42.4 75.9 44.4 26.8 39.8 46.6 20.7 47.8 47.8 69.1 398.1 24.3 55.8 136.0 79.2 36.2 28.5 22.4 25.0 25.7 43.7 20.3 104.2 112.2 91.2 26.2 59.5 44.8 51.1 31.3 32.1 58.3 27.9 20.7 251.1 65.4 60.6 35.0 37.7 71.1 64.8 79.9 27.9 22.1 21.6 33.8 19.4 48.9 7.1 28.3 8.9 14.6 6.9 5.3 12.7 10.8 10.9 5.9 355.0 10.0 33.3 18.9 12.5 11.5 42.6 63.3 75.4 60.7 49.5 57.5 64.0 63.0 54.6 46.2 63.6 50.9 430.3 41.7 18.6 55.8 69.4 29.3 23.5 22.5 37.0 31.5 86.5 37.8 17.6 15.7 28.9 27.6 18.8 10.8 77.5 20.3 99.7 18.0 242.6 114.8 46.7 205.9 19.7 86.5 33.0 20.7 10.8 34.0 35.2 240.5 34.7 104.3 286.3 11.1 51.6 37.0 54.6 14.0 61.1 127.2 48.1 740.3 26.4 115.1 35.6 62.8 76.1 31.4 34.0 23.1 44.4 41.8 15.2 17.3 269.1 39.5 9.6 24.8 69.5 17.2 39.5 36.4 36.3 45.1 42.5 25.1 30.4 13.3 51.6 64.3 11.5 39.1 SELP "CD62, CD62P, GMP140, GRMP, PADGEM, PSEL" ENSG00000174175 "Selectin P" P16109 1 169588849-169630193 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 14.7;Endothelial cells: 51.8;Hepatic stellate cells: 33.9;Macrophages: 10.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 8.3;T-reg: 8.8" "Group enriched" "Detected in many" 7 "granulocytes: 8.3;T-cells: 8.8" "Group enriched" "Detected in some" 38 "EFO-21: 36.0;HEL: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002145, HPA002655, HPA005990" Enhanced NA NA 520000000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002145: AB_563984, HPA002655: AB_1078480, HPA005990: AB_1078479" "unprognostic (3.37e-2)" "unprognostic (2.98e-4)" "unprognostic (4.11e-1)" "unprognostic (1.46e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.12e-4)" "unprognostic (5.30e-4)" "unprognostic (4.14e-2)" "unprognostic (3.59e-1)" "unprognostic (1.74e-1)" "unprognostic (1.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.19e-1)" "unprognostic (8.24e-3)" "unprognostic (1.74e-2)" "unprognostic (7.85e-3)" "unprognostic (1.66e-1)" 11.3 2.3 0.2 11.9 0.6 2.2 10.6 0.0 0.6 8.9 3.7 3.3 5.1 6.4 4.1 5.1 6.7 9.5 6.7 0.3 0.0 5.6 2.5 12.6 7.0 0.2 0.2 1.8 1.2 3.1 2.2 6.3 0.2 6.1 4.1 0.0 2.7 5.7 1.0 3.6 4.8 14.2 0.1 1.0 2.8 0.7 0.7 2.6 4.0 1.8 12.6 14.4 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.3 0.4 0.6 0.0 0.2 0.0 1.1 0.5 0.2 0.0 0.1 0.2 0.1 2.1 0.3 0.0 0.1 8.8 7.8 0.2 0.6 0.0 0.6 0.3 0.0 0.2 0.2 0.2 0.1 0.7 0.2 14.7 0.0 3.6 0.3 0.4 3.7 0.1 0.0 0.6 0.0 0.2 0.1 1.9 1.5 0.0 1.8 0.0 2.6 0.1 0.0 0.0 0.0 2.0 0.1 0.1 51.8 0.0 5.2 0.5 0.2 0.0 1.5 0.0 0.0 0.0 0.0 33.9 0.4 0.2 0.0 0.2 0.0 0.0 1.5 3.6 0.1 0.3 10.1 3.6 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.1 0.1 3.4 4.1 0.5 0.0 0.0 0.3 SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 100.8" "Cell type enhanced" "Detected in many" "Adipocytes: 40.2;Bipolar cells: 23.4;Endothelial cells: 24.4;Hepatic stellate cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 108.1;HUVEC TERT2: 187.0;RT4: 112.3;SK-BR-3: 170.2;TIME: 338.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" NA NA 1700000 7900000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" 33.8 9.0 8.8 8.6 5.7 2.7 31.9 5.1 8.1 28.3 12.0 10.5 13.4 14.5 5.4 100.8 15.6 10.8 22.6 5.0 9.2 49.2 4.8 46.2 3.7 10.2 12.7 3.6 6.7 5.5 11.1 30.4 8.7 32.7 6.3 22.0 24.6 32.5 10.4 75.1 12.5 9.1 6.3 50.7 17.3 2.4 21.8 6.1 27.1 6.1 12.6 27.0 55.4 4.7 13.9 3.1 0.7 14.2 0.2 1.3 3.0 8.0 24.2 6.5 10.2 5.4 6.1 0.5 77.9 1.1 0.7 47.5 6.9 100.7 2.4 0.1 1.8 0.8 108.1 18.5 5.7 1.7 3.2 6.2 55.3 15.1 45.4 90.7 187.0 1.2 2.9 0.1 1.3 12.4 1.5 7.5 8.6 6.2 10.1 11.8 0.0 0.5 7.2 112.3 1.1 2.6 12.8 170.2 0.3 10.4 67.2 7.3 338.6 4.2 31.9 29.7 5.5 0.2 0.0 0.9 0.3 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 5.7 5.1 8.1 5.0 9.2 10.2 12.7 8.7 6.3 21.8 4.7 40.2 0.0 1.1 0.0 0.2 6.8 3.0 9.2 5.7 23.4 10.7 6.0 9.2 1.5 6.6 18.4 10.4 11.2 0.6 5.5 0.0 0.3 0.0 6.5 2.4 24.4 0.0 0.0 0.7 0.8 0.5 1.1 16.3 6.9 0.0 0.2 25.4 0.6 1.4 6.7 1.1 10.7 0.0 0.3 0.8 0.3 0.3 0.2 0.0 3.7 0.0 8.7 0.0 0.0 0.1 6.8 3.8 0.0 0.0 2.5 5.7 0.7 5.4 19.8 0.0 0.5 2.5 0.0 0.4 17.7 8.9 6.3 0.4 0.2 5.2 8.6 SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 80.1;breast: 64.2" "Cell type enriched" "Detected in many" 6 "Adipocytes: 151.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "ASC diff: 26.1;Hep G2: 7.1;HUVEC TERT2: 7.4;THP-1: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" NA NA 5600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" 80.1 1.9 9.9 3.4 9.4 0.1 64.2 18.9 11.4 5.1 6.2 6.8 3.0 5.9 1.3 4.5 5.2 5.9 18.6 8.4 9.0 19.8 1.3 23.9 1.6 10.8 10.0 3.2 3.1 1.8 2.4 26.7 11.3 4.6 3.7 0.4 10.6 2.5 12.8 12.7 9.6 3.9 9.9 8.0 5.7 1.3 12.1 1.7 7.7 18.6 1.8 8.3 7.8 9.1 0.0 0.1 0.1 0.2 26.1 0.2 2.5 0.0 0.0 0.0 0.0 0.7 0.3 3.3 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 3.9 0.2 7.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 7.4 2.6 0.0 0.4 0.0 0.3 0.2 4.3 1.2 0.7 0.1 0.0 0.0 4.1 0.0 0.3 0.5 0.5 0.0 0.4 0.5 0.1 1.9 6.5 2.9 0.1 2.4 0.0 0.0 0.5 2.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 9.9 9.4 18.9 11.4 8.4 9.0 10.8 10.0 11.3 9.9 12.1 9.1 151.5 3.2 1.3 0.0 0.3 0.4 0.1 0.1 0.0 1.7 5.1 5.5 10.7 0.0 0.0 3.7 0.0 1.7 0.9 0.3 0.0 0.0 3.0 2.8 1.6 20.4 9.6 0.0 0.0 0.0 0.2 3.6 1.1 5.8 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 5.0 0.3 0.5 0.0 24.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 1.2 0.2 0.0 9.4 0.0 0.1 0.2 0.0 4.1 3.0 0.1 0.1 0.5 0.1 7.5 0.4 0.1 0.2 0.0 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.4;breast: 10.8" "Cell type enriched" "Detected in some" 7 "Adipocytes: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HUVEC TERT2: 34.0;TIME: 40.1" "Not detected" "Not detected" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" 12.4 1.2 2.9 0.6 2.5 0.0 10.8 2.2 3.3 0.7 1.1 1.2 0.3 1.2 0.1 0.5 1.2 0.6 8.9 2.3 2.2 4.2 0.8 3.2 0.4 3.0 2.6 0.7 0.5 0.5 0.6 4.7 3.1 1.0 0.4 1.4 0.7 0.5 3.1 0.9 0.9 0.6 2.3 0.7 0.9 7.5 3.3 0.2 1.9 1.8 0.0 1.5 0.8 2.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.1 0.2 0.0 0.0 34.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 40.1 0.0 0.8 2.7 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.5 2.2 3.3 2.3 2.2 3.0 2.6 3.1 2.3 3.3 2.4 42.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 5.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 SPNS2 SLC62A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.0" "Cell type enhanced" "Detected in many" "Adipocytes: 32.7;Endothelial cells: 34.5;Microglial cells: 37.5;Oligodendrocytes: 97.8;Urothelial cells: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.0;RPTEC TERT1: 161.7;SK-BR-3: 76.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" 17.3 2.6 13.1 5.2 14.0 7.9 14.7 13.1 18.2 14.6 0.1 6.5 12.2 8.6 0.6 51.0 7.8 12.1 10.7 14.1 12.1 28.6 3.8 28.3 4.9 26.4 16.2 1.8 10.0 1.1 2.1 7.9 28.9 5.3 2.1 0.6 16.5 2.0 4.4 24.8 10.8 4.8 13.9 11.4 21.0 1.3 15.5 1.7 8.5 3.9 13.3 6.6 22.6 25.1 9.7 1.2 0.0 0.2 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.5 8.1 0.5 11.8 0.0 0.1 0.5 0.0 0.7 0.0 0.1 0.2 0.6 0.2 0.0 0.1 3.0 0.0 0.0 0.2 0.0 0.0 0.0 4.2 4.7 0.0 0.0 0.0 3.8 0.2 17.0 0.1 17.6 0.3 0.8 0.0 0.3 161.7 0.5 5.4 0.2 0.0 76.7 0.0 5.1 2.7 7.5 0.2 0.2 0.7 0.3 0.1 0.3 0.3 0.1 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.1 14.0 13.1 18.2 14.1 12.1 26.4 16.2 28.9 13.9 15.5 25.1 32.7 6.4 10.6 1.6 0.2 1.8 0.4 2.1 0.0 1.2 4.3 3.6 1.2 22.8 16.2 22.0 0.0 1.3 0.2 2.8 1.9 16.7 0.2 0.5 1.0 34.5 0.0 3.2 23.4 3.0 30.5 1.7 26.0 2.8 0.0 0.0 12.5 6.7 1.1 6.7 26.2 12.7 2.0 0.3 1.6 0.2 0.6 1.9 1.8 37.5 0.0 0.4 0.0 3.5 97.8 18.6 0.0 0.4 1.2 11.7 1.9 24.3 16.9 1.1 0.0 1.4 3.1 0.6 0.5 0.6 2.4 1.9 1.6 0.1 1.1 39.8 SPRY1 hSPRY1 ENSG00000164056 "Sprouty RTK signaling antagonist 1" O43609 4 123396795-123403760 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.1" "Cell type enhanced" "Detected in many" "Adipocytes: 771.3;Endothelial cells: 352.8;Fibroblasts: 222.3;Leydig cells: 448.0;Skeletal myocytes: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 61.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 95.4;AN3-CA: 194.1;ASC diff: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013538, HPA051369, HPA070554" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" Nucleoplasm "CAB013538: AB_2533452, HPA051369: AB_2681457, HPA070554: AB_2686280" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.06e-1)" "unprognostic (7.15e-2)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (1.36e-1)" "unprognostic (9.43e-2)" "unprognostic (6.99e-2)" "unprognostic (4.32e-1)" "unprognostic (4.06e-1)" "unprognostic (3.11e-2)" "unprognostic (8.77e-3)" "unprognostic (1.21e-3)" "unprognostic (4.48e-2)" "unprognostic (1.54e-2)" "unprognostic (1.27e-1)" 238.1 38.4 6.5 22.3 7.9 22.7 154.3 7.6 9.0 71.9 26.6 46.6 15.7 40.9 24.1 42.5 81.2 83.8 73.1 7.5 8.4 35.6 21.5 58.3 13.0 5.5 5.4 30.0 31.8 37.4 27.3 49.6 5.8 52.0 27.5 19.0 45.2 24.7 49.9 79.8 25.2 57.7 5.6 17.0 35.1 10.2 7.6 29.2 92.7 49.9 10.1 74.4 71.0 6.0 6.3 1.8 95.4 194.1 76.5 51.6 6.4 0.4 4.9 0.3 2.0 5.8 10.3 0.0 42.4 2.9 0.4 1.2 2.6 4.6 0.7 0.1 10.0 2.2 0.0 31.0 21.7 14.2 0.1 21.1 2.5 0.7 2.1 10.5 8.1 2.2 1.7 1.9 4.7 0.7 16.4 34.8 22.8 22.6 32.0 7.1 10.3 0.2 13.2 14.5 14.5 12.3 0.1 19.4 19.6 10.1 1.9 0.0 20.2 1.2 0.2 0.4 2.9 1.0 0.1 0.2 1.4 2.6 3.2 0.1 0.4 6.5 1.1 0.2 33.1 29.8 4.0 9.2 0.1 61.2 5.7 6.4 0.4 14.2 0.1 1.7 0.0 2.0 6.5 7.9 7.6 9.0 7.5 8.4 5.5 5.4 5.8 5.6 7.6 6.0 771.3 28.9 28.3 14.4 16.2 49.6 17.3 37.3 68.9 86.2 22.8 69.6 16.9 32.9 20.6 27.6 33.3 12.7 21.6 10.4 80.3 5.0 2.5 45.9 41.9 352.8 26.5 5.7 5.0 10.9 1.7 222.3 8.2 67.4 9.5 0.2 166.3 5.9 10.1 6.7 2.2 15.0 14.2 15.3 37.9 10.5 448.0 17.1 46.2 5.6 0.7 158.3 0.0 7.5 0.3 7.0 6.3 57.9 6.1 16.8 8.1 38.7 11.7 84.5 151.2 245.0 81.6 6.2 9.6 37.0 43.3 3.1 57.3 1.8 17.9 13.5 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232220 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 151.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 153.7;HMC-1: 70.6;HUVEC TERT2: 31.2;JURKAT: 60.0;K-562: 48.9;MOLT-4: 26.3;TIME: 34.4" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "CAB017805: , HPA047866: AB_2680192, HPA073983: AB_2732246" "unprognostic (2.63e-1)" "unprognostic (2.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.95e-3)" "unprognostic (1.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (2.76e-2)" "unprognostic (2.19e-1)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" 7.5 2.5 4.9 1.0 4.5 29.4 6.3 4.7 4.4 2.9 3.0 2.1 0.8 2.9 0.6 1.8 3.5 2.3 5.9 4.6 4.6 4.4 1.5 13.0 1.4 6.5 7.1 1.2 0.9 0.9 1.7 6.9 6.8 2.1 1.3 0.2 1.1 0.8 2.1 1.7 3.1 2.7 6.9 7.1 1.8 0.9 6.4 0.4 5.4 2.5 0.7 2.4 2.5 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.2 0.1 153.7 0.0 0.0 0.0 0.0 70.6 0.0 0.0 0.0 0.0 0.0 31.2 60.0 48.9 0.1 0.0 0.0 26.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.1 34.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.5 4.9 4.5 4.7 4.4 4.6 4.6 6.5 7.1 6.8 6.9 6.4 6.8 23.9 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.1 0.1 3.7 1.5 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.1 18.1 0.0 151.5 0.0 0.0 0.3 0.6 0.0 0.0 36.8 0.0 26.7 0.1 10.6 0.0 0.1 0.0 0.0 1.6 1.5 18.2 0.0 4.8 1.8 29.0 0.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 1.3 0.4 0.1 1.0 0.0 2.0 0.0 0.0 0.0 TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 603797-610398 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "heart muscle: 27.8;skeletal muscle: 13.2;tongue: 9.1" "Cell type enriched" "Detected in some" 6 "Adipocytes: 260.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 10.6;HMC-1: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" 7.0 0.6 1.3 0.1 1.2 0.0 4.6 1.2 1.4 0.2 0.9 1.6 0.1 0.8 0.0 0.3 0.4 0.1 27.8 1.1 1.2 1.5 0.2 0.6 0.1 1.3 1.3 0.2 0.3 0.1 0.4 3.3 1.4 0.3 0.0 0.0 0.6 0.0 13.2 0.2 0.5 0.2 1.3 0.0 0.6 2.0 1.3 0.0 0.5 9.1 0.0 0.9 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.9 10.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 1.5 0.0 1.3 0.0 3.0 0.0 1.4 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 1.2 1.4 1.1 1.2 1.3 1.3 1.4 1.3 1.3 1.2 260.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.6 0.5 0.6 1.0 15.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.7 0.2 0.2 41.2 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.6 0.0 0.1 7.1 0.0 0.1 1.7 0.5 0.0 0.0 0.0 0.4 0.2 0.0 0.5 0.0 2.8 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 13.1 3.7 23.3 2.3 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.0 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.5" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Bipolar cells: 183.8;Horizontal cells: 208.6;Inhibitory neurons: 494.3;Oligodendrocyte precursor cells: 262.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 54 "basophil: 5.3" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.3" "Cell line enhanced" "Detected in some" "A549: 10.3;HUVEC TERT2: 6.7;REH: 7.1;SH-SY5Y: 10.2;THP-1: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" NA NA 6100000 "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" 2.4 0.7 2.9 0.7 2.3 0.0 2.1 3.2 4.4 3.3 0.0 1.0 0.3 2.8 0.8 0.5 2.1 2.6 0.7 4.2 3.5 7.5 0.6 1.1 0.3 2.8 4.9 2.5 0.4 1.2 1.6 4.1 2.5 3.4 0.7 5.0 0.5 2.1 0.2 0.5 0.5 2.4 3.4 0.9 0.5 0.8 4.8 0.2 1.9 1.2 0.2 1.8 1.7 2.4 0.0 10.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 1.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 7.1 0.0 0.0 0.3 0.1 0.7 10.2 0.0 0.3 0.0 1.6 0.1 19.2 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 3.2 4.4 4.2 3.5 2.8 4.9 2.5 3.4 4.8 2.4 46.9 22.4 8.2 150.5 0.0 2.7 1.4 0.0 1.2 183.8 0.8 0.5 1.5 21.5 2.8 55.2 112.6 23.5 0.1 0.4 7.9 7.0 1.2 4.9 22.4 42.6 41.7 0.0 56.6 2.2 4.3 8.1 0.5 18.8 0.0 6.1 28.2 1.3 2.2 208.6 494.3 0.8 0.0 1.5 2.9 0.5 24.2 0.5 12.4 105.9 0.0 20.7 0.0 262.4 5.4 5.5 6.8 1.5 0.1 7.7 0.1 8.8 0.1 9.3 0.0 10.6 5.0 1.6 1.1 0.6 2.4 51.9 0.8 21.5 1.2 1.1 TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1235.1;Sertoli cells: 427.3;Syncytiotrophoblasts: 1946.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 322.7;CAPAN-2: 178.9;EFO-21: 403.6;HaCaT: 181.4;HBEC3-KT: 211.9;HUVEC TERT2: 173.4;TIME: 376.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" NA NA 370000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" 173.7 40.8 19.0 18.5 17.7 0.9 150.5 17.9 19.9 86.8 16.4 83.2 26.7 101.8 10.7 31.0 82.4 23.9 230.7 15.2 17.9 177.7 22.7 85.7 8.5 19.6 18.3 38.8 31.0 13.2 25.3 183.6 19.8 71.2 16.5 1.0 63.8 40.6 46.6 37.0 51.6 36.5 16.4 119.6 66.4 6.2 21.2 3.8 115.1 30.6 5.3 88.4 70.2 17.1 96.6 0.2 0.0 0.5 0.8 0.2 322.7 14.9 1.9 0.7 0.4 44.5 178.9 0.2 403.6 13.4 7.0 181.4 0.2 211.9 0.1 0.7 0.1 0.1 7.3 11.5 4.5 0.1 0.5 0.2 37.9 0.0 7.6 0.1 173.4 0.1 2.4 0.4 0.0 0.0 0.7 0.6 0.9 52.6 6.1 0.4 0.1 0.4 57.0 72.6 0.4 0.5 38.0 125.6 4.2 18.8 7.5 0.3 376.6 0.3 91.6 0.7 2.8 0.4 0.5 1.6 0.2 0.2 3.3 2.0 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.8 0.4 0.1 0.1 0.1 0.0 19.0 17.7 17.9 19.9 15.2 17.9 19.6 18.3 19.8 16.4 21.2 17.1 345.4 9.6 5.8 0.7 2.7 11.0 121.5 244.1 8.0 0.0 32.0 73.0 46.7 37.1 28.6 132.4 0.0 1235.1 2.6 158.9 1.9 378.7 1.4 8.4 3.2 161.4 11.4 13.5 0.1 92.2 223.5 35.0 50.0 14.4 14.7 49.7 306.6 4.4 89.3 0.0 1.1 35.5 14.2 8.8 10.3 0.7 7.5 4.2 23.2 13.1 2.0 0.2 0.0 0.5 0.0 344.6 115.3 4.1 0.2 131.4 45.2 80.9 9.1 0.4 427.3 9.5 357.4 0.3 0.8 4.9 6.5 1946.1 3.8 2.7 59.7 219.4 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TM4SF1 "L6, M3S1" ENSG00000169908 "Transmembrane 4 L six family member 1" P30408 3 149369022-149377692 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 5463.1;Endothelial cells: 1843.0;Pancreatic endocrine cells: 2557.3;Prostatic glandular cells: 2717.0;Urothelial cells: 4902.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 703.8;hTERT-RPE1: 925.5;HUVEC TERT2: 633.3;LHCN-M2: 687.7;OE19: 672.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002760, HPA002823" Uncertain NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB002760: , HPA002823: AB_1079221" "unprognostic (1.94e-1)" "unprognostic (2.25e-2)" "unprognostic (5.20e-2)" "unprognostic (4.79e-2)" "unprognostic (2.89e-2)" "unprognostic (2.47e-3)" "unprognostic (3.85e-3)" "unprognostic (2.74e-2)" "unprognostic (5.09e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.06e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (4.67e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.43e-6)" 365.9 71.3 41.9 50.5 43.1 2.6 192.8 44.1 68.2 82.6 65.6 61.6 38.3 74.9 58.2 210.9 74.7 237.6 181.7 42.2 45.2 155.1 92.6 229.8 25.2 45.1 43.9 49.7 211.7 19.9 20.2 194.6 47.7 79.9 59.9 6.0 180.9 32.0 50.2 63.5 62.2 94.6 45.4 120.5 129.7 19.5 53.5 17.0 72.5 64.2 60.2 150.9 115.5 45.9 367.9 401.9 0.0 1.0 108.4 422.2 0.6 115.2 455.5 23.9 8.8 159.7 703.8 0.1 351.3 23.5 545.5 434.0 1.9 80.0 22.9 0.9 0.0 3.9 391.8 521.8 39.4 0.0 0.5 40.0 19.1 169.7 81.5 925.5 633.3 0.0 0.3 0.8 687.7 0.5 0.0 0.7 1.5 672.9 170.7 0.2 0.9 0.8 449.3 54.8 0.2 0.5 46.8 25.1 4.4 6.0 0.8 1.7 404.7 233.6 38.9 4.8 244.3 0.5 0.7 1.1 337.4 0.4 62.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 43.1 44.1 68.2 42.2 45.2 45.1 43.9 47.7 45.4 53.5 45.9 1131.0 576.9 342.3 0.3 7.5 278.0 5463.1 668.3 272.6 0.1 956.5 363.1 24.0 274.5 984.3 57.0 0.0 0.8 17.0 176.6 0.0 1383.5 5.2 514.1 168.0 1843.0 39.2 15.6 0.0 1600.9 0.9 297.2 147.8 1807.5 31.5 0.2 1263.6 21.8 1.9 0.0 0.0 15.9 382.5 27.8 222.1 11.3 255.7 35.6 300.6 30.9 26.4 0.0 0.0 0.0 0.3 2557.3 251.8 176.0 11.1 2717.0 0.3 1.2 238.5 0.0 322.1 37.7 311.0 6.6 1.4 925.8 253.7 1.4 44.1 44.2 46.6 4902.9 TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050958, HPA054475" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA050958: AB_2681290, HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" 5.7 2.3 2.6 9.9 2.5 9.3 5.7 2.2 2.7 4.3 2.2 7.0 6.2 2.9 1.1 8.4 4.1 8.2 3.0 2.0 2.4 3.8 5.3 6.6 13.4 3.4 2.8 0.8 2.4 2.7 0.8 7.1 3.1 2.9 7.1 0.2 4.8 2.5 1.5 4.9 6.5 3.9 2.8 6.8 6.5 0.5 3.4 6.4 3.0 2.8 14.0 10.8 5.8 2.8 18.7 33.0 1.7 0.1 1.2 6.4 0.1 3.8 2.3 1.9 5.2 25.4 31.8 42.9 41.9 2.4 9.1 34.6 29.5 47.2 3.1 10.7 0.2 22.7 20.4 14.7 16.2 12.3 20.7 11.0 38.2 41.1 35.0 5.5 21.9 1.4 35.7 14.9 8.9 14.5 0.4 7.8 22.6 33.0 20.0 0.3 0.0 31.2 24.4 39.5 0.9 1.1 9.3 23.0 0.0 6.9 12.3 9.3 31.3 0.1 0.2 1.8 0.1 17.4 26.7 32.7 0.2 3.9 0.5 2.8 6.1 5.7 5.0 2.6 13.8 15.3 16.1 10.2 6.3 19.1 15.7 9.2 0.6 6.1 2.6 0.0 20.8 6.5 2.6 2.5 2.2 2.7 2.0 2.4 3.4 2.8 3.1 2.8 3.4 2.8 21.5 3.2 8.7 0.7 22.3 23.6 20.7 9.1 21.6 0.2 8.2 7.1 1.1 7.2 15.5 11.0 0.0 0.1 3.1 10.1 0.0 10.1 0.1 8.6 1.9 16.6 2.4 1.3 0.4 4.0 0.4 2.2 10.2 23.9 7.6 0.7 2.9 5.1 3.1 0.0 0.4 7.0 8.2 2.2 12.7 0.0 0.0 8.5 3.6 9.4 4.2 0.0 2.1 1.0 0.5 20.3 7.3 0.0 14.0 11.7 4.5 2.9 5.7 0.0 0.0 0.9 1.1 0.0 0.5 25.6 27.4 0.0 12.8 0.1 9.1 27.4 TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.4" "Cell type enhanced" "Detected in many" "dendritic cells: 268.7;Kupffer cells: 200.5;Langerhans cells: 288.0;Macrophages: 230.2;monocytes: 175.3;T-cells: 138.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 34.0;K-562: 45.7;THP-1: 51.8;U-87 MG: 30.8;U-937: 37.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" NA NA 3230000 8100000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" 45.6 5.4 3.9 68.4 3.8 52.1 34.7 4.8 17.9 14.3 5.6 12.8 16.8 11.6 0.4 5.5 14.6 15.6 10.9 3.7 9.0 7.5 15.7 32.0 32.1 18.3 7.2 6.3 5.9 2.3 4.5 35.8 10.6 6.4 10.8 0.8 6.5 2.6 10.7 7.8 23.9 16.8 9.0 53.3 16.4 2.2 8.9 12.7 7.6 6.3 21.3 28.9 8.8 14.1 0.0 0.3 4.1 0.0 9.6 13.5 8.9 1.1 2.0 4.0 4.3 1.8 34.0 0.2 0.6 3.9 5.6 0.0 0.8 0.0 2.2 14.5 0.0 0.0 0.2 0.0 25.2 0.3 3.8 14.8 0.0 13.0 0.0 7.2 19.6 0.2 45.7 6.4 1.5 0.0 0.0 8.1 0.2 4.9 1.4 1.2 0.4 25.9 0.0 0.8 0.0 0.1 0.6 0.4 1.4 6.4 0.0 51.8 7.8 5.3 0.2 27.0 0.0 1.9 0.0 0.0 30.8 37.0 1.4 0.6 127.1 18.2 48.4 260.5 26.5 13.5 34.4 40.5 71.7 8.4 9.8 15.5 138.0 13.4 387.1 15.1 70.9 150.4 3.9 3.8 4.8 17.9 3.7 9.0 18.3 7.2 10.6 9.0 8.9 14.1 99.4 9.6 15.9 0.7 42.8 16.8 3.9 1.0 1.2 0.2 3.2 4.1 3.6 5.7 6.5 3.7 0.0 0.9 268.7 12.8 0.0 0.5 0.6 1.7 5.1 46.0 0.0 7.4 0.2 0.6 6.3 13.2 12.8 4.9 2.5 1.4 31.1 17.0 72.6 0.0 0.2 3.0 0.0 200.5 288.0 1.2 2.1 230.2 16.0 30.9 175.3 0.3 109.2 0.0 0.1 0.7 4.2 0.4 72.5 8.0 25.8 0.4 1.5 1.2 32.9 6.8 9.8 0.0 0.9 0.7 10.5 30.1 138.4 1.9 4.8 8.8 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 TSPAN13 "NET-6, TM4SF13" ENSG00000106537 "Tetraspanin 13" O95857 7 16753755-16784536 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 303.4;Alveolar cells type 1: 496.8;Cytotrophoblasts: 293.7;Intestinal goblet cells: 404.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 99.6;plasmacytoid DC: 231.7" "Group enriched" "Detected in many" 42 "B-cells: 99.6;dendritic cells: 231.7" "Cell line enhanced" "Detected in many" "OE19: 484.5;SCLC-21H: 215.3;SK-BR-3: 314.0;T-47d: 587.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007426 Uncertain Uncertain Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA007426: AB_10603137" "unprognostic (3.22e-1)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.56e-5)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (5.69e-2)" "unprognostic (6.63e-2)" "prognostic favorable (2.20e-4)" "unprognostic (1.50e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" 65.6 81.1 32.1 29.1 37.2 26.1 76.3 20.5 95.8 60.7 17.0 83.5 88.9 20.0 36.9 19.7 19.9 55.5 23.9 36.2 67.1 7.8 47.4 185.5 56.2 24.1 28.3 3.1 95.8 14.1 83.6 67.1 28.7 51.1 99.9 19.4 168.0 35.8 9.3 16.6 77.3 20.3 19.8 26.3 108.0 8.9 27.1 20.4 35.1 13.7 47.2 41.0 16.1 29.3 47.4 38.6 47.8 50.9 6.0 0.2 13.2 99.0 16.1 2.6 4.9 137.4 70.9 1.4 24.7 35.8 12.3 71.2 56.2 83.2 21.6 1.4 60.3 20.3 15.3 14.8 13.3 1.9 4.0 5.6 35.4 5.2 5.9 27.4 30.1 20.7 67.0 0.4 2.9 135.4 2.8 2.6 33.4 484.5 46.5 54.0 0.2 48.5 153.1 90.1 215.3 32.5 18.0 314.0 4.8 68.1 587.9 5.2 2.9 1.4 17.0 1.5 33.1 28.4 0.8 1.0 44.2 0.8 69.1 0.6 0.0 0.2 0.0 0.0 0.1 47.9 0.1 0.0 1.1 99.6 0.0 0.1 3.9 3.6 0.1 231.7 0.0 5.6 32.1 37.2 20.5 95.8 36.2 67.1 24.1 28.3 28.7 19.8 27.1 29.3 303.4 496.8 82.5 10.1 94.0 42.6 84.9 96.0 31.9 78.2 141.7 46.7 19.1 41.5 137.6 29.5 8.4 293.7 131.6 95.4 7.9 68.0 1.6 27.8 6.5 97.9 107.7 60.2 79.3 203.9 109.3 22.5 89.2 67.1 9.5 1.0 7.5 26.3 40.8 15.2 56.8 404.6 122.1 18.9 22.6 2.5 0.6 9.4 32.0 9.4 61.3 3.5 2.1 23.6 7.6 109.1 88.8 0.7 49.9 127.4 99.8 0.9 63.2 8.1 32.9 2.2 22.0 1.7 19.5 39.4 39.6 201.1 8.9 6.1 125.3 173.6 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 324.4" "Cell type enhanced" "Detected in some" "Adipocytes: 66.4;Cytotrophoblasts: 16.5;Endothelial cells: 38.5;Hofbauer cells: 43.1;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1345.3;non-classical monocyte: 1608.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 908.5;SK-MEL-30: 1012.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 49000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA005573: AB_2667366, HPA018944: AB_2669986" "unprognostic (5.36e-2)" "unprognostic (5.98e-2)" "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (2.30e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.14e-2)" "unprognostic (4.26e-2)" "prognostic favorable (1.94e-4)" "unprognostic (4.84e-2)" "unprognostic (3.21e-1)" "unprognostic (3.53e-3)" "unprognostic (1.37e-1)" "unprognostic (9.45e-2)" "unprognostic (1.62e-1)" "unprognostic (5.92e-3)" 100.7 67.9 40.3 185.6 44.4 70.5 65.4 40.1 45.5 35.9 45.2 67.8 44.8 39.6 70.3 54.4 50.8 48.7 157.6 44.2 56.0 83.6 47.9 207.5 139.0 72.0 52.6 21.2 47.5 39.2 63.4 324.4 65.3 49.1 72.0 37.8 49.5 38.3 74.7 28.4 67.7 76.2 47.6 110.6 70.1 67.7 55.0 61.7 159.9 67.0 86.2 107.7 30.7 44.9 91.2 85.7 54.6 319.1 78.7 110.7 87.3 117.4 220.7 232.1 301.4 57.4 80.2 101.7 105.5 277.4 59.7 151.1 158.8 130.3 153.1 154.4 48.3 64.1 60.9 72.3 908.5 184.9 101.6 126.9 186.9 141.3 290.1 74.5 225.0 66.1 202.8 255.0 107.5 178.0 64.3 87.1 55.4 94.1 152.2 51.4 86.5 64.9 119.3 80.8 145.7 84.9 69.4 58.7 1012.4 70.5 153.6 234.7 153.1 25.7 58.9 269.2 61.3 446.4 277.1 191.9 295.0 144.2 205.5 96.5 471.7 610.4 41.5 1345.3 38.4 71.4 34.5 38.4 337.9 68.0 24.8 28.6 170.9 44.5 1608.2 54.7 44.8 672.7 40.3 44.4 40.1 45.5 44.2 56.0 72.0 52.6 65.3 47.6 55.0 44.9 66.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 16.5 3.7 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 11.5 5.5 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 16.6 0.5 0.0 0.0 0.0 WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 229.3;Endothelial cells: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 212.1;RPTEC TERT1: 151.1;SK-MEL-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: AB_2216639, CAB068248: AB_2665648, HPA007415: AB_1080602" "unprognostic (1.85e-2)" "unprognostic (2.24e-2)" "unprognostic (3.41e-3)" "unprognostic (1.33e-2)" "unprognostic (7.94e-2)" "unprognostic (1.37e-1)" "unprognostic (2.41e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-2)" "unprognostic (2.34e-1)" "unprognostic (1.63e-2)" "unprognostic (3.32e-1)" "unprognostic (1.17e-3)" "unprognostic (2.76e-2)" "unprognostic (2.53e-1)" "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" 41.6 13.8 19.2 22.4 20.8 0.2 37.2 18.9 19.6 41.8 32.6 74.9 8.0 42.1 13.4 35.8 33.7 39.6 36.4 20.7 53.9 45.9 19.0 41.2 7.2 52.6 39.9 43.9 31.8 14.1 13.6 44.0 35.9 34.5 13.5 4.2 27.6 32.1 13.2 24.8 21.6 43.7 37.1 19.5 32.7 7.2 23.0 4.7 31.6 15.0 6.1 59.2 34.3 41.0 58.9 80.5 40.6 48.7 48.6 86.8 43.0 32.6 57.5 17.7 17.8 46.7 53.2 0.1 212.1 45.0 53.3 36.1 28.4 28.5 17.9 22.0 19.3 0.0 18.6 37.8 27.3 0.0 0.1 45.3 7.4 61.8 26.6 65.4 136.3 0.0 0.0 0.2 61.7 9.2 0.2 0.2 8.2 0.2 96.6 0.0 50.6 0.4 151.1 9.4 0.0 0.4 21.1 17.2 160.2 31.5 26.5 1.6 94.2 29.0 16.2 24.8 67.4 0.6 0.5 0.8 66.8 0.1 78.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.1 19.2 20.8 18.9 19.6 20.7 53.9 52.6 39.9 35.9 37.1 23.0 41.0 125.7 64.1 89.7 60.4 1.1 51.7 229.3 34.6 60.9 2.2 58.1 56.8 46.8 141.5 87.8 49.7 4.2 12.2 2.0 0.5 7.9 72.0 21.9 136.3 89.1 221.2 0.0 3.2 8.7 27.1 82.3 77.9 10.2 144.4 7.6 45.0 111.4 21.9 4.1 0.0 6.1 1.2 10.2 6.0 32.3 7.9 57.8 4.6 30.2 94.6 2.1 11.0 0.0 7.5 12.7 45.8 0.0 126.4 2.9 86.7 1.2 59.8 53.9 2.0 59.2 76.1 58.0 2.2 0.8 46.3 35.5 14.8 6.5 48.4 2.4 93.5 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6