Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ADAP2 CENTA2 ENSG00000184060 "ArfGAP with dual PH domains 2" Q9NPF8 17 30906344-30959322 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 86.2;Hofbauer cells: 195.8;Kupffer cells: 186.8;Macrophages: 97.2;monocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 22.4;intermediate monocyte: 34.3;myeloid DC: 12.6;non-classical monocyte: 43.5" "Group enriched" "Detected in many" 9 "dendritic cells: 12.6;monocytes: 43.5" "Cell line enhanced" "Detected in some" "EFO-21: 7.0;HAP1: 17.6;HEK 293: 11.0;RPMI-8226: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (4.00e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.25e-1)" "unprognostic (9.26e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (3.12e-4)" "unprognostic (2.38e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-2)" 11.3 8.9 6.6 15.3 7.6 3.9 4.6 6.7 8.5 2.9 9.1 6.5 5.7 3.2 2.9 3.1 3.3 9.2 4.4 6.2 8.0 5.1 11.0 9.8 9.8 12.1 9.6 1.9 3.1 9.1 1.9 19.7 10.4 2.4 8.0 1.3 3.1 3.1 1.8 6.7 5.6 9.8 8.6 22.5 4.3 2.0 14.7 4.6 3.2 6.4 6.7 9.0 2.2 12.9 0.1 1.7 0.2 0.4 0.4 0.5 4.5 0.1 0.0 0.3 0.1 0.7 0.7 1.0 7.0 0.1 0.2 0.1 17.6 0.2 0.3 0.4 11.0 0.0 1.0 2.0 2.9 0.4 1.9 1.1 4.4 0.9 0.6 0.2 0.0 0.0 0.2 1.8 0.6 3.6 0.1 0.3 0.1 0.4 0.1 0.3 0.0 22.9 2.4 2.3 0.3 0.1 0.3 0.2 0.1 1.5 3.8 2.9 0.0 0.4 1.1 0.8 0.1 0.8 0.5 1.0 0.4 0.4 0.0 0.2 22.4 0.0 0.0 34.3 0.0 3.0 0.1 0.1 12.6 2.1 0.1 0.1 1.7 0.0 43.5 0.4 0.4 6.6 6.6 7.6 6.7 8.5 6.2 8.0 12.1 9.6 10.4 8.6 14.7 12.9 5.4 3.2 5.2 2.6 8.6 2.0 0.5 0.5 2.2 0.8 0.7 2.4 1.5 1.5 0.9 0.0 2.1 23.5 0.2 3.1 0.0 0.3 0.6 1.7 0.6 7.8 0.0 0.4 1.1 1.4 86.2 1.9 0.0 1.2 3.8 0.4 4.6 1.6 195.8 0.0 1.4 0.6 0.0 186.8 13.1 0.5 0.9 97.2 0.0 40.3 88.2 0.6 2.1 2.0 1.3 0.9 0.9 0.4 2.6 0.9 0.3 8.3 2.2 2.8 39.5 1.2 26.5 0.9 0.9 1.0 6.5 26.4 1.6 0.2 0.3 0.6 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 BCAT1 BCT1 ENSG00000060982 "Branched chain amino acid transaminase 1" P54687 12 24810024-24949101 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Branched-chain amino acid biosynthesis" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 58.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 203.2;Early spermatids: 161.4;Exocrine glandular cells: 139.9;Langerhans cells: 265.8;Late spermatids: 370.3" "Group enriched" "Detected in all" 4 "endometrial cancer: 19.0;glioma: 10.7;lung cancer: 7.2;ovarian cancer: 24.0;testis cancer: 27.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 17.1" "Group enriched" "Detected in many" 10 "dendritic cells: 5.8;monocytes: 17.1" "Cell line enhanced" "Detected in many" "HDLM-2: 261.3;NTERA-2: 287.4;RH-30: 310.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048592 Uncertain NA NA 97000 "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 34: Spermatids - Unknown function" "HPA048592: AB_2680454" "unprognostic (1.90e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (3.05e-5)" "unprognostic (9.49e-3)" "unprognostic (4.22e-2)" "unprognostic (4.77e-3)" "unprognostic (1.97e-3)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.38e-4)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.44e-2)" "unprognostic (7.55e-2)" "prognostic unfavorable (8.54e-4)" 6.7 5.9 4.1 7.1 5.7 2.4 2.1 11.1 10.6 3.6 0.0 3.0 0.8 8.6 1.0 2.0 7.2 4.4 1.8 3.0 19.6 1.2 1.3 9.6 6.4 19.4 19.8 7.2 58.2 0.4 6.6 15.2 22.7 0.9 2.6 14.5 1.7 0.8 0.7 0.6 3.6 5.7 6.4 2.0 1.8 7.1 14.0 5.2 1.2 2.0 5.3 4.1 1.3 7.9 30.3 12.1 106.8 0.2 30.5 59.0 54.9 60.9 40.6 33.4 55.2 67.1 83.1 114.0 0.3 100.7 6.5 12.0 77.2 0.5 88.2 261.3 15.4 91.1 2.0 37.3 112.3 105.9 31.6 77.4 2.0 85.1 17.8 73.0 114.3 56.9 88.5 1.1 28.7 0.6 65.2 30.1 287.4 0.0 8.1 0.1 310.3 1.4 0.1 10.4 0.1 60.1 0.1 0.2 0.5 114.8 0.2 45.2 150.8 19.7 72.9 80.4 58.1 13.2 13.9 152.7 69.9 62.4 0.3 0.0 2.3 0.0 0.0 3.6 0.1 1.1 0.0 0.1 5.8 0.0 0.0 0.0 1.0 0.1 17.1 3.4 0.2 1.0 4.1 5.7 11.1 10.6 3.0 19.6 19.4 19.8 22.7 6.4 14.0 7.9 1.7 16.0 26.0 1.6 1.3 8.7 0.1 2.5 0.0 203.2 0.3 0.3 1.6 1.5 2.2 0.0 2.1 61.2 4.3 0.0 1.9 1.8 161.4 41.5 92.6 16.8 0.0 20.8 39.6 139.9 23.2 27.6 0.0 89.1 11.4 117.4 7.9 0.3 72.3 42.1 81.8 0.0 14.2 87.1 265.8 370.3 7.2 59.9 7.2 38.4 22.3 7.1 0.0 84.4 57.4 49.6 0.0 4.1 0.7 0.2 0.0 0.1 3.3 12.2 6.6 14.9 17.4 1.9 1.6 0.5 7.2 22.4 2.8 41.3 0.1 0.1 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement component 5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in many" "Early spermatids: 14.4;Hepatic stellate cells: 23.9;Kupffer cells: 48.6;Macrophages: 34.5" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.0" "Group enriched" "Detected in some" 4 "MCF7: 20.7;T-47d: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 41: Macrophages - Immune response" "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" 4.2 1.2 1.1 4.1 0.8 5.8 2.2 1.2 2.9 1.2 1.8 1.3 0.4 0.7 0.4 0.6 2.3 0.7 2.1 2.4 0.5 1.2 1.9 6.5 0.9 1.3 0.7 0.6 0.8 0.1 0.9 2.2 0.7 0.4 0.4 0.4 1.2 0.3 0.3 1.4 1.5 1.0 0.5 14.1 1.1 3.1 0.8 0.3 0.9 0.4 3.2 1.2 1.3 1.3 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.7 0.4 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 5.2 0.1 0.0 0.8 1.5 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.4 0.0 20.7 0.1 2.4 0.2 0.0 0.1 0.3 0.1 2.7 0.1 0.3 0.2 0.1 0.1 0.1 0.0 0.1 24.8 0.3 0.2 0.8 0.2 0.5 0.1 0.3 0.3 0.9 0.8 1.4 0.1 17.8 2.7 11.9 0.3 2.3 0.4 0.3 0.2 0.2 0.6 0.4 0.2 0.2 33.0 0.3 4.4 0.3 0.6 0.7 1.1 0.8 1.2 2.9 2.4 0.5 1.3 0.7 0.7 0.5 0.8 1.3 0.6 3.2 1.9 0.3 1.1 0.4 2.8 0.1 0.0 1.3 4.7 2.8 1.6 2.8 2.6 1.8 2.1 0.1 1.7 0.0 0.0 0.0 14.4 0.5 0.5 1.7 0.0 3.2 0.6 0.0 0.2 2.1 0.0 1.1 1.3 6.1 23.9 1.2 8.3 0.0 0.1 0.0 0.0 48.6 4.6 3.0 0.0 34.5 0.0 1.0 8.3 0.3 1.0 0.0 0.1 0.0 0.0 0.4 1.3 2.0 0.0 0.3 0.8 4.2 0.0 4.0 1.0 0.2 0.4 0.1 0.9 0.1 1.3 4.1 0.0 1.9 CARD9 ENSG00000187796 "Caspase recruitment domain family member 9" Q9H257 9 136361903-136373681 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.0;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 14.1;Hofbauer cells: 21.2;Horizontal cells: 15.2;Kupffer cells: 18.8;Langerhans cells: 12.9;Macrophages: 22.3;monocytes: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 57.6;non-classical monocyte: 50.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 22.5;HMC-1: 69.7;NB-4: 50.0;THP-1: 63.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059502 Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA059502: AB_2684042" "unprognostic (7.03e-2)" "unprognostic (5.61e-2)" "unprognostic (8.62e-3)" "unprognostic (2.06e-2)" "unprognostic (2.75e-1)" "unprognostic (2.11e-2)" "unprognostic (3.89e-3)" "unprognostic (6.36e-2)" "unprognostic (2.64e-1)" "unprognostic (1.55e-2)" "unprognostic (7.68e-3)" "unprognostic (6.97e-2)" "unprognostic (2.02e-6)" "unprognostic (2.52e-1)" "unprognostic (4.87e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" 1.2 1.3 0.5 4.7 0.5 13.0 1.2 2.5 1.0 2.0 0.3 1.0 1.3 0.8 0.4 1.0 1.8 1.0 0.5 0.5 0.7 1.0 0.9 3.4 1.2 1.9 0.9 0.3 0.5 0.1 0.8 0.9 1.3 1.8 0.4 0.2 1.1 1.0 0.2 2.7 1.8 1.1 1.4 9.9 0.6 0.4 1.1 0.4 0.4 0.0 1.5 1.2 1.1 1.7 0.1 0.0 0.3 0.0 0.0 0.0 4.6 9.5 0.3 0.2 0.0 0.7 0.0 0.0 0.1 3.5 0.0 0.0 0.3 0.0 0.1 0.0 0.2 22.5 0.1 6.8 4.9 12.2 69.7 0.0 0.1 0.2 0.2 0.0 0.1 0.0 5.3 0.0 0.0 0.2 0.0 50.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 12.3 0.0 16.0 0.1 0.0 4.1 63.7 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.1 16.0 0.0 6.9 34.5 11.5 0.0 57.6 0.9 0.0 0.0 0.0 26.0 0.0 0.0 0.0 2.3 0.7 50.5 0.1 0.5 14.1 0.5 0.5 2.5 1.0 0.5 0.7 1.9 0.9 1.3 1.4 1.1 1.7 0.8 0.0 4.6 4.6 1.1 1.8 0.6 0.3 3.4 0.2 4.2 4.3 2.6 0.0 4.9 3.7 0.0 0.4 2.2 0.4 1.9 0.1 1.0 1.2 14.1 1.1 0.0 2.5 2.1 0.0 0.4 2.1 1.5 1.4 10.8 0.4 0.7 0.1 21.2 15.2 1.1 0.0 0.0 18.8 12.9 6.9 0.3 22.3 1.8 6.5 16.3 4.6 3.1 0.0 0.2 0.0 0.1 0.0 1.4 0.1 0.0 0.3 0.6 0.9 0.0 0.3 1.5 1.0 1.5 0.9 1.7 0.4 1.4 0.2 0.2 0.6 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CEACAM4 CGM7 ENSG00000105352 "CEA cell adhesion molecule 4" O75871 19 41618971-41627074 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 32.6" "Cell type enhanced" "Detected in some" "Kupffer cells: 41.1;Macrophages: 20.9;monocytes: 9.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "neutrophil: 122.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 122.7" "Cell line enriched" "Detected in single" 6 "U-937: 4.1" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.10e-2)" "unprognostic (1.52e-2)" "unprognostic (1.24e-1)" "unprognostic (4.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.83e-2)" "unprognostic (9.11e-2)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (2.17e-1)" "unprognostic (2.09e-9)" "unprognostic (3.65e-2)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (4.34e-1)" 2.1 0.5 0.1 4.8 0.1 21.3 0.5 0.1 0.2 0.4 0.2 0.7 0.3 0.3 0.8 1.0 1.0 1.0 0.8 0.1 0.1 0.8 1.0 5.7 0.9 0.2 0.2 0.2 1.2 0.0 0.3 0.3 0.2 1.1 0.2 0.0 0.8 0.0 0.2 0.3 1.8 1.0 0.1 32.6 0.8 0.1 0.2 0.3 0.4 0.6 0.6 0.7 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 30.1 5.6 0.0 23.1 0.1 0.7 1.2 0.0 23.3 0.0 0.7 0.0 122.7 0.0 9.9 0.2 11.3 12.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 3.9 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.1 0.0 0.0 0.0 0.0 41.1 1.6 0.2 0.0 20.9 1.8 1.9 9.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLEC7A "CD369, CLECSF12, dectin-1, hDectin-1, SCARE2" ENSG00000172243 "C-type lectin domain containing 7A" Q9BXN2 12 10116777-10130258 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 84.0;lung: 30.9;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.2;Kupffer cells: 415.2;Langerhans cells: 291.5;Macrophages: 255.5;monocytes: 186.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 249.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 16 "Karpas-707: 192.2;U-266/84: 168.1" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.03e-2)" "unprognostic (5.49e-2)" "unprognostic (5.19e-2)" "unprognostic (5.88e-3)" "unprognostic (2.10e-1)" "unprognostic (9.87e-2)" "unprognostic (7.46e-2)" "unprognostic (4.40e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.83e-2)" "unprognostic (3.89e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" 9.9 5.9 2.2 44.5 2.0 84.0 4.5 2.6 3.7 3.5 3.3 7.5 5.6 3.2 3.7 9.7 5.8 11.1 5.7 1.9 3.3 3.5 11.0 30.9 14.4 5.0 2.7 2.4 2.9 2.0 2.7 7.3 4.0 3.3 7.3 1.7 7.3 3.2 1.3 3.8 8.6 8.7 3.6 34.2 4.6 1.5 3.8 10.0 2.6 2.0 11.9 9.1 4.8 6.1 0.3 0.4 0.1 0.2 0.0 0.0 1.1 0.0 0.5 0.2 0.1 0.1 0.4 0.1 0.1 0.0 1.1 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.9 0.7 0.1 0.8 0.1 0.0 0.2 0.1 0.2 0.0 192.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 4.3 0.0 5.2 0.3 0.2 0.3 0.6 0.0 1.4 0.4 0.1 0.3 0.1 0.2 0.2 0.2 11.4 168.1 0.1 0.3 1.0 0.2 1.4 122.9 2.2 0.3 137.2 0.5 0.3 0.3 0.2 60.6 0.3 0.3 0.2 249.6 0.4 148.1 1.0 0.4 40.4 2.2 2.0 2.6 3.7 1.9 3.3 5.0 2.7 4.0 3.6 3.8 6.1 2.0 12.8 15.1 0.3 5.9 3.7 0.2 0.9 8.6 0.0 3.1 2.8 0.9 0.0 9.7 0.0 0.0 1.5 2.1 0.2 0.0 0.1 1.7 0.2 0.1 9.3 0.0 0.0 0.1 0.0 14.1 2.4 0.0 0.1 6.3 0.0 6.1 2.1 87.2 0.0 0.1 0.0 4.1 415.2 291.5 2.2 0.3 255.5 3.6 27.2 186.1 0.0 8.2 0.0 0.0 0.0 1.1 0.0 1.1 0.1 0.0 1.3 2.4 0.4 13.1 1.1 1.0 0.1 0.5 13.2 3.0 5.3 4.1 0.0 0.0 0.5 CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 568.8;lymphoid tissue: 583.8" "Cell type enhanced" "Detected in many" "B-cells: 523.9;dendritic cells: 588.7;Hofbauer cells: 494.4;Kupffer cells: 395.8;Macrophages: 342.7;monocytes: 583.7;NK-cells: 968.1;T-cells: 663.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 924.0;HL-60: 645.7;HMC-1: 1086.7;JURKAT: 603.0;MOLT-4: 632.5;NB-4: 771.8;RPMI-8226: 980.9;U-698: 618.2;U-937: 829.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 45000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB046473: AB_10602363, HPA051132: AB_2681355" "unprognostic (4.17e-3)" "unprognostic (3.64e-3)" "unprognostic (3.86e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.41e-1)" "prognostic favorable (4.42e-4)" "unprognostic (1.99e-2)" "unprognostic (8.27e-3)" "unprognostic (8.26e-3)" "unprognostic (4.30e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (2.55e-1)" "unprognostic (2.37e-2)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" 29.1 20.8 34.4 306.4 37.1 568.8 11.2 24.9 52.0 10.6 23.6 26.8 44.3 10.0 3.1 22.5 17.9 45.0 11.3 36.9 31.9 11.5 13.1 49.5 583.8 37.6 32.0 6.4 8.4 4.3 9.3 18.4 32.2 11.4 15.3 0.9 32.9 7.3 6.7 17.6 111.0 22.2 35.8 321.4 49.0 4.8 33.9 257.6 12.7 8.8 309.1 57.6 10.4 50.0 3.1 3.6 10.9 21.5 0.1 0.1 6.1 2.6 0.7 5.4 3.0 0.7 6.9 924.0 6.1 0.9 1.5 4.4 5.2 10.8 1.3 302.3 2.5 97.9 0.5 15.0 1.7 645.7 1086.7 2.8 0.0 4.3 0.5 0.4 2.0 603.0 1.5 467.6 3.4 80.7 632.5 771.8 4.0 3.1 6.4 340.0 17.5 980.9 1.3 5.1 17.3 13.0 2.2 110.7 2.0 0.2 1.9 373.0 1.6 4.0 9.0 2.7 3.1 348.5 497.7 618.2 3.0 829.6 6.3 797.2 773.6 2671.1 637.5 859.7 597.8 505.5 567.3 625.6 843.2 512.0 537.1 566.2 1318.9 531.0 898.0 482.1 858.7 1647.2 34.4 37.1 24.9 52.0 36.9 31.9 37.6 32.0 32.2 35.8 33.9 50.0 6.3 22.4 32.5 0.3 523.9 11.3 1.2 3.2 2.2 1.2 4.7 5.5 1.5 17.2 6.0 1.8 0.0 4.6 588.7 2.3 0.0 3.5 0.5 1.1 2.0 12.3 6.0 60.2 3.3 0.9 17.4 9.5 18.8 1.3 83.7 0.6 21.8 4.8 494.4 0.0 1.7 2.2 6.1 395.8 197.9 1.2 0.6 342.7 32.0 4.7 583.7 0.8 968.1 1.5 0.4 11.1 47.5 0.0 201.4 0.8 1.0 4.8 3.5 0.9 6.6 2.9 5.1 0.1 0.9 2.4 9.1 4.9 663.0 2.7 3.3 0.9 CR1 "CD35, KN" ENSG00000203710 "Complement C3b/C4b receptor 1 (Knops blood group)" P17927 1 207496147-207641765 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.2;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in some" "B-cells: 32.6;Erythroid cells: 20.4;Kupffer cells: 59.1;Macrophages: 24.9;monocytes: 13.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 53.7;eosinophil: 17.2;neutrophil: 15.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 53.7" "Group enriched" "Detected in some" 9 "HL-60: 9.9;HMC-1: 21.8;NB-4: 9.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB002491, CAB016271, HPA042455, HPA043579, HPA049348" Enhanced NA NA 33000000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "CAB002491: AB_563553, CAB016271: AB_627040, HPA042455: AB_2678006, HPA043579: AB_2678564, HPA049348: AB_2680723" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (2.75e-2)" "unprognostic (6.12e-2)" "unprognostic (1.58e-2)" "unprognostic (7.14e-2)" "unprognostic (2.84e-1)" "unprognostic (3.86e-2)" "unprognostic (2.02e-1)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-3)" "unprognostic (4.38e-2)" "unprognostic (3.32e-2)" "unprognostic (6.45e-2)" "unprognostic (3.50e-3)" 13.2 0.8 0.1 27.2 0.5 10.5 0.6 0.1 2.9 1.2 1.3 1.5 1.3 0.5 0.2 0.9 1.4 2.1 0.6 0.2 0.2 2.5 2.6 3.2 20.1 0.7 0.5 0.2 0.3 0.1 0.2 9.1 1.6 0.2 1.5 0.0 0.4 0.4 0.2 0.1 4.4 6.3 0.1 24.4 1.7 0.6 2.1 1.6 0.3 1.0 17.9 6.7 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 9.9 21.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.7 4.2 17.2 0.0 2.4 0.7 4.5 0.9 0.4 0.3 2.2 0.2 0.1 15.6 0.0 2.3 0.0 0.0 1.3 0.1 0.5 0.1 2.9 0.2 0.2 0.7 0.5 1.6 0.1 2.1 1.8 0.3 0.0 4.2 0.3 32.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.9 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.2 0.2 0.0 20.4 0.3 0.0 0.1 0.6 0.0 0.2 1.3 0.3 0.0 0.4 9.7 0.0 0.4 0.0 0.0 59.1 1.4 0.0 0.0 24.9 0.0 1.9 13.3 0.0 0.0 1.5 4.4 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.3 1.3 0.5 0.0 0.0 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1475.9;Hofbauer cells: 3763.5;Macrophages: 1512.6;Proximal enterocytes: 1699.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 2596.6;hTERT-RPE1: 2780.1;SK-BR-3: 2488.5" "CAB000109, HPA003001" Supported "Secreted to blood" NA NA 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" 318.6 734.6 147.0 204.9 181.9 499.0 244.0 186.0 156.5 270.8 672.7 298.0 387.6 170.7 82.8 319.4 171.6 438.4 444.1 187.8 223.6 691.6 464.8 539.6 241.0 247.6 206.6 130.7 284.8 137.3 131.5 180.7 228.6 138.2 153.4 48.3 422.1 231.7 590.3 340.9 398.3 105.0 188.9 442.0 287.2 88.9 334.4 78.1 182.1 178.2 123.1 296.4 307.5 367.1 204.6 578.9 51.4 246.2 586.5 206.3 112.1 149.4 362.2 161.8 182.8 147.5 2596.6 49.2 376.8 285.8 1265.6 1072.2 63.7 142.6 35.8 206.7 222.9 70.4 92.5 196.5 736.2 171.4 787.7 350.9 621.6 82.5 136.9 2780.1 128.2 62.1 89.2 267.6 263.3 832.6 47.0 110.9 153.1 719.7 247.9 62.5 72.5 191.2 586.6 610.8 84.2 94.8 173.3 2488.5 535.0 68.6 1022.8 232.6 170.3 556.8 92.9 79.0 216.7 432.0 382.3 26.8 867.7 468.6 509.6 211.2 578.7 170.1 156.5 309.9 90.6 28.8 72.1 110.3 144.5 18.8 82.5 107.4 319.5 192.3 265.2 120.3 89.2 489.1 147.0 181.9 186.0 156.5 187.8 223.6 247.6 206.6 228.6 188.9 334.4 367.1 139.3 112.2 228.6 48.3 62.8 72.0 223.5 473.2 71.7 168.6 108.9 113.8 251.9 314.5 459.5 548.1 110.5 211.7 156.1 1475.9 109.5 911.4 3.3 118.1 67.4 128.3 159.6 132.6 18.3 370.1 165.0 157.0 237.5 203.4 474.3 119.4 695.7 678.9 3763.5 264.2 25.2 418.2 498.5 1187.8 67.5 14.6 108.4 1512.6 227.7 20.6 382.6 179.0 256.4 27.2 42.2 392.3 832.5 128.2 122.5 111.7 1699.4 311.8 270.3 102.1 111.7 70.7 135.2 26.6 63.5 141.2 82.1 471.3 155.0 96.0 399.1 357.8 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 DOCK2 KIAA0209 ENSG00000134516 "Dedicator of cytokinesis 2" Q92608 5 169637268-170083382 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 61.6;lung: 16.4;lymphoid tissue: 51.4" "Cell type enhanced" "Detected in many" "B-cells: 53.3;dendritic cells: 78.1;Kupffer cells: 93.2;Macrophages: 78.0;Microglial cells: 173.3;monocytes: 72.5;T-cells: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 123.4;HDLM-2: 172.7;HL-60: 132.7;HMC-1: 135.8;MOLT-4: 94.5;U-698: 112.4;U-937: 85.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036469 Enhanced NA NA 46000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA036469: AB_2675140" "unprognostic (3.45e-2)" "unprognostic (1.84e-2)" "unprognostic (3.90e-3)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (5.92e-3)" "unprognostic (3.47e-1)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (2.03e-3)" "unprognostic (1.47e-1)" "unprognostic (2.22e-2)" "unprognostic (6.95e-2)" "unprognostic (7.24e-2)" 7.7 3.6 1.4 34.4 2.4 61.6 3.6 1.9 2.6 3.1 2.8 7.6 5.0 2.3 1.3 3.3 2.4 9.6 1.6 1.8 2.5 1.2 5.5 16.4 42.5 6.4 3.7 1.6 1.9 1.5 0.8 7.3 4.6 1.8 7.8 0.2 2.6 1.9 0.9 1.2 9.6 7.0 4.6 36.5 8.1 1.7 6.3 51.4 1.5 1.4 46.9 9.9 1.1 8.4 0.4 0.3 0.0 0.0 0.0 0.4 0.0 3.3 0.0 8.2 14.3 0.0 0.0 123.4 4.5 13.0 3.9 0.1 0.1 0.6 19.5 172.7 0.3 71.0 3.4 0.0 0.2 132.7 135.8 0.4 0.0 6.3 0.0 5.5 0.5 65.1 1.4 60.3 8.7 0.0 94.5 27.0 0.2 0.0 0.0 59.9 4.8 49.3 3.0 0.0 0.4 0.0 0.5 0.1 0.0 0.0 0.1 64.8 0.4 5.9 6.8 4.1 9.1 18.6 40.9 112.4 7.3 85.1 0.2 19.7 28.6 22.0 12.3 48.6 12.6 13.2 11.3 12.6 29.8 9.7 7.8 9.5 29.4 13.5 72.1 10.9 11.7 24.0 1.4 2.4 1.9 2.6 1.8 2.5 6.4 3.7 4.6 4.6 6.3 8.4 1.4 0.0 3.9 2.0 53.3 0.9 0.2 0.0 0.0 0.0 0.7 2.3 1.7 0.0 2.5 0.0 0.0 0.3 78.1 0.2 0.0 0.0 5.9 0.3 0.3 1.5 0.0 15.1 9.6 0.0 0.3 1.3 1.5 0.3 33.6 0.8 1.8 1.3 42.6 0.0 4.9 0.0 0.0 93.2 31.1 5.6 0.3 78.0 5.4 173.3 72.5 0.0 47.4 4.0 21.7 0.2 0.1 0.0 39.6 0.1 0.0 0.2 0.7 0.1 6.6 0.7 0.6 2.8 1.4 0.2 2.0 0.8 50.8 0.3 0.1 0.1 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 EMB MGC71745 ENSG00000170571 Embigin Q6PCB8 5 50396192-50443248 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 152.5;intestine: 72.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 108.4;dendritic cells: 133.3;NK-cells: 153.5;Proximal enterocytes: 137.5;T-cells: 150.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 281.5;U-937: 124.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.01e-3)" "unprognostic (8.65e-2)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-2)" "unprognostic (8.31e-2)" "unprognostic (2.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (2.76e-5)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (1.22e-2)" "unprognostic (8.86e-3)" 18.4 22.4 1.7 28.4 1.6 152.5 12.1 4.0 2.9 8.6 2.4 9.7 72.0 3.1 2.7 8.0 5.8 12.9 5.1 1.9 5.4 2.5 4.7 15.9 55.9 6.9 7.8 2.1 2.1 24.2 8.4 13.4 5.6 29.1 11.6 10.5 5.5 20.4 1.3 32.3 68.3 8.0 3.5 25.0 14.3 10.9 3.7 28.4 20.7 3.6 48.4 16.8 2.8 3.1 38.8 2.9 6.5 0.1 2.9 8.7 0.5 1.7 0.0 2.7 0.3 0.3 91.6 74.3 2.1 3.2 0.0 55.7 15.3 43.5 0.4 24.0 38.8 34.5 10.2 0.0 0.5 69.9 0.2 0.6 23.3 6.9 28.2 44.6 0.0 28.8 0.0 86.8 52.4 41.0 43.2 39.3 27.2 0.0 19.9 65.5 0.2 98.6 0.0 29.8 21.2 19.9 0.0 10.1 1.1 13.4 4.3 281.5 0.1 0.1 32.5 0.2 0.3 1.0 0.0 59.3 0.1 124.1 8.3 9.5 34.1 38.7 44.5 4.4 54.1 20.7 39.9 41.0 22.3 13.7 23.5 31.8 30.2 37.3 1.4 25.7 53.6 42.8 1.7 1.6 4.0 2.9 1.9 5.4 6.9 7.8 5.6 3.5 3.7 3.1 3.3 67.3 17.3 1.6 78.1 18.2 2.0 21.2 8.6 3.3 6.5 8.0 1.9 10.0 27.7 0.0 108.4 12.1 133.3 1.2 0.0 0.8 0.6 1.0 0.4 3.8 7.3 21.9 51.9 0.9 8.5 7.8 15.8 0.4 19.0 0.0 20.7 1.6 20.6 1.7 28.7 11.3 8.2 31.4 86.4 1.5 2.8 63.5 10.6 41.2 78.0 2.1 153.5 0.0 1.6 15.7 4.4 6.8 71.1 9.6 137.5 0.4 34.3 9.0 0.0 2.3 4.6 1.0 3.8 6.4 12.6 8.5 150.9 0.0 15.4 2.4 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804110 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 195.3;lymphoid tissue: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 119.6;Kupffer cells: 215.3;Macrophages: 178.5;monocytes: 89.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4199.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 4199.5" "Group enriched" "Detected in some" 5 "LHCN-M2: 17.2;U-87 MG: 67.1" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" 69.6 10.0 3.8 166.0 4.4 195.3 5.3 4.1 8.7 8.2 5.7 4.6 3.1 3.7 0.5 8.9 15.4 28.6 7.5 3.6 8.1 4.5 21.4 50.8 12.7 15.2 8.2 2.4 11.2 5.1 3.5 45.1 11.9 3.1 3.3 2.6 4.1 2.3 1.8 1.3 5.2 42.9 8.6 129.2 5.4 2.2 9.9 8.4 3.1 22.8 10.3 66.9 2.7 18.2 0.5 0.8 0.3 0.4 1.0 2.1 0.5 0.2 0.0 0.5 2.0 0.3 0.7 1.2 0.6 0.0 3.9 0.4 0.0 0.0 0.1 0.1 0.0 0.7 0.9 1.0 6.0 0.3 0.5 4.8 0.2 1.8 1.8 9.2 0.0 0.3 0.1 0.6 17.2 0.9 0.1 0.3 0.4 0.3 0.7 0.3 0.7 0.0 1.5 0.5 0.2 0.3 0.6 0.1 0.5 0.2 1.0 1.1 1.0 2.0 0.4 0.1 3.5 0.2 0.0 0.5 67.1 1.7 0.1 317.1 759.9 204.9 1.6 319.7 1.5 0.7 1.0 0.7 174.1 1.0 1.0 1.2 4199.5 0.4 201.8 8.1 1.3 420.3 3.8 4.4 4.1 8.7 3.6 8.1 15.2 8.2 11.9 8.6 9.9 18.2 0.1 16.0 25.7 0.0 1.8 0.6 0.3 0.0 0.0 1.0 0.1 0.3 0.2 0.0 15.5 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.8 0.0 0.1 6.3 0.0 2.5 0.2 0.0 1.6 4.7 0.5 0.1 26.5 0.0 2.5 2.1 119.6 0.0 0.1 0.0 0.0 215.3 4.7 2.0 0.3 178.5 0.0 3.7 89.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.4 8.8 0.3 6.6 0.6 0.8 0.6 0.8 0.2 0.0 3.0 2.5 0.0 0.0 0.1 GNA15 GNA16 ENSG00000060558 "G protein subunit alpha 15" P30679 19 3136033-3163749 "Plasma proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.6;esophagus: 108.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 141.5;Langerhans cells: 190.6;Macrophages: 78.3;Suprabasal keratinocytes: 95.8;Urothelial cells: 173.8" "Group enriched" "Detected in all" 4 "cervical cancer: 39.9;head and neck cancer: 46.4;lung cancer: 17.3;pancreatic cancer: 11.9;urothelial cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 67.1" "Group enriched" "Detected in many" 4 "dendritic cells: 67.1;granulocytes: 19.4;monocytes: 29.1" "Cell line enhanced" "Detected in some" "HBEC3-KT: 65.4;HMC-1: 152.1;MOLT-4: 162.4;NB-4: 59.8;REH: 119.3;THP-1: 62.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043113 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA043113: AB_10967343" "prognostic favorable (7.57e-5)" "unprognostic (6.06e-2)" "unprognostic (3.43e-1)" "prognostic favorable (2.01e-4)" "unprognostic (4.34e-2)" "unprognostic (2.09e-1)" "unprognostic (1.14e-2)" "unprognostic (5.38e-3)" "unprognostic (1.82e-1)" "unprognostic (3.22e-2)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (4.26e-6)" "unprognostic (1.04e-1)" "unprognostic (2.16e-3)" "unprognostic (2.36e-1)" "unprognostic (2.07e-1)" 6.8 3.1 4.0 12.4 3.8 75.6 4.6 4.0 7.3 13.3 4.7 2.5 1.7 1.3 0.4 108.8 2.4 4.6 1.9 4.1 4.1 2.0 1.4 13.1 4.2 5.4 4.5 0.8 1.2 0.4 1.4 7.6 5.1 11.6 1.8 0.1 19.5 2.5 0.6 50.8 2.5 3.1 4.9 8.8 4.3 1.4 6.6 32.0 1.2 0.9 12.1 28.1 41.6 6.4 44.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 18.7 0.1 0.1 0.0 0.1 36.2 0.0 65.4 0.0 0.1 0.0 19.1 0.1 0.0 0.0 27.2 152.1 0.0 40.0 0.2 26.2 0.0 0.0 16.6 0.1 0.3 0.0 0.0 162.4 59.8 0.1 2.9 0.0 119.3 0.0 0.2 0.0 23.6 0.2 0.0 4.6 0.2 0.2 0.0 0.0 62.1 0.1 0.0 0.2 0.2 0.3 0.2 0.0 0.1 0.3 29.8 0.1 19.4 29.1 14.3 0.0 21.8 1.1 0.0 2.0 0.3 28.8 0.0 0.0 0.0 6.9 4.4 15.5 67.1 8.7 13.3 4.0 3.8 4.0 7.3 4.1 4.1 5.4 4.5 5.1 4.9 6.6 6.4 1.0 9.6 8.8 0.0 2.2 67.2 141.5 65.5 9.1 0.2 7.4 3.7 0.5 0.0 39.0 3.7 0.0 0.5 27.6 0.5 0.0 0.7 0.5 1.4 0.5 3.1 6.6 21.0 1.3 0.0 0.8 2.5 3.6 3.9 34.3 0.0 0.7 0.0 66.5 0.0 0.4 2.2 57.0 36.2 190.6 0.8 0.0 78.3 21.4 7.5 32.0 0.0 0.0 0.0 0.2 13.2 0.3 0.0 3.6 69.3 0.0 0.1 21.7 0.1 19.7 0.3 3.3 4.0 2.0 38.0 95.8 0.4 19.6 0.1 1.4 173.8 GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.7;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 16.5;Cone photoreceptor cells: 20.9;Kupffer cells: 37.0;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "eosinophil: 40.2;NK-cell: 10.9" "Group enriched" "Detected in many" 10 "granulocytes: 40.2;NK-cells: 10.9" "Cell line enriched" "Detected in single" 30 "HMC-1: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" 0.1 0.9 0.7 2.3 0.5 0.1 0.6 0.8 0.7 0.3 0.4 1.1 1.7 0.3 0.1 0.4 0.3 0.6 0.1 0.5 1.0 0.3 0.7 0.2 3.2 1.4 0.7 0.2 0.1 0.2 0.1 0.0 0.7 0.2 1.1 0.0 0.4 0.4 0.0 0.4 2.7 0.3 0.6 1.1 0.9 0.0 1.3 0.5 0.3 0.0 6.9 0.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.4 40.2 0.0 2.5 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.3 10.9 2.4 0.0 0.0 0.2 0.7 0.5 0.8 0.7 0.5 1.0 1.4 0.7 0.7 0.6 1.3 0.8 0.7 0.0 7.2 2.0 5.5 4.7 5.2 2.8 0.6 16.5 1.2 0.3 0.4 4.3 5.9 1.8 20.9 0.9 3.7 3.1 0.0 2.0 0.2 1.0 3.4 3.1 1.2 0.8 1.7 1.1 0.2 2.9 1.5 1.4 0.0 1.4 3.3 1.3 1.3 13.5 2.2 2.0 2.0 37.0 7.7 0.2 4.1 13.9 3.6 0.0 3.4 1.7 12.3 10.6 1.1 2.8 5.1 3.0 1.3 3.6 6.9 0.3 1.1 17.2 0.0 3.4 2.3 1.6 1.1 0.3 2.7 0.7 12.6 3.9 3.4 3.8 GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1420.7;Kupffer cells: 892.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2057.5;intermediate monocyte: 1122.4;myeloid DC: 1534.2;neutrophil: 851.2;non-classical monocyte: 548.1;plasmacytoid DC: 1331.9" "Group enriched" "Detected in all" 9 "dendritic cells: 1534.2;granulocytes: 851.2;monocytes: 2057.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" NA NA 138000000 110000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" 158.9 123.2 61.5 160.4 67.2 478.5 120.7 67.7 97.3 156.7 73.9 189.8 130.9 108.3 134.0 534.0 87.1 157.3 153.0 61.0 69.7 167.4 118.9 309.5 183.2 81.0 71.5 73.8 108.9 87.8 84.4 183.2 87.6 111.7 110.3 12.5 262.9 100.6 60.6 189.7 179.0 91.9 71.8 349.8 127.9 59.4 94.3 67.8 127.7 45.9 107.8 150.0 198.3 97.3 119.3 197.5 52.7 159.5 443.2 231.8 181.2 147.3 447.5 231.6 309.8 86.3 294.0 364.0 299.4 217.6 312.9 185.3 68.6 334.5 75.8 55.8 186.8 38.4 93.8 175.2 245.5 61.6 493.6 332.4 450.5 188.1 106.0 391.2 269.8 64.3 75.1 51.3 148.8 183.1 32.8 172.8 44.3 110.5 334.0 97.7 180.8 433.0 248.2 145.9 54.7 74.7 201.0 92.7 360.9 138.0 209.4 229.0 340.7 437.6 104.6 300.5 97.8 116.3 313.9 122.3 268.1 149.6 124.2 215.1 2057.5 176.5 35.1 1122.4 27.8 174.0 37.1 31.1 1534.2 112.2 27.8 26.5 851.2 30.6 548.1 1331.9 55.4 1613.4 61.5 67.2 67.7 97.3 61.0 69.7 81.0 71.5 87.6 71.8 94.3 97.3 113.0 86.6 83.3 12.7 82.8 112.7 151.1 574.2 97.9 23.6 85.7 69.7 90.7 133.0 332.7 218.8 18.8 429.1 195.7 494.8 9.8 447.7 2.1 103.8 83.8 170.9 124.3 38.7 6.8 307.3 324.1 149.4 83.6 372.5 75.5 90.0 207.8 84.7 1420.7 47.1 6.6 214.6 146.5 892.0 360.8 6.8 60.9 699.2 208.1 20.6 501.6 58.9 20.6 11.1 11.8 285.3 581.7 57.2 65.8 70.7 312.1 120.5 70.0 11.8 85.5 45.4 83.3 25.1 72.2 255.5 96.5 640.0 30.8 89.6 274.5 175.6 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 177.8;Excitatory neurons: 82.2;Microglial cells: 74.9;Oligodendrocyte precursor cells: 141.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" 2.2 4.8 29.6 0.4 35.8 0.4 3.0 41.4 51.7 1.7 9.2 1.0 0.0 1.0 0.4 0.9 1.0 0.8 1.0 37.4 17.6 1.1 0.4 1.5 0.2 26.9 23.4 0.6 1.9 10.4 1.6 1.4 27.0 3.8 0.3 9.4 1.1 1.1 0.3 0.8 0.4 0.3 21.6 13.0 0.6 0.8 24.5 0.8 0.6 0.4 0.7 3.9 1.1 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.6 35.8 41.4 51.7 37.4 17.6 26.9 23.4 27.0 21.6 24.5 33.5 0.1 0.0 0.0 3.6 0.6 0.3 0.2 0.0 0.0 177.8 9.2 2.7 0.6 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 1.8 3.0 0.0 82.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 28.9 0.1 0.0 23.6 4.0 12.8 0.6 12.8 0.0 74.9 0.0 6.3 0.0 141.3 2.4 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 13.0 6.6 4.5 0.2 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 IGSF6 DORA ENSG00000140749 "Immunoglobulin superfamily member 6" O95976 16 21639550-21652608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8" "Group enriched" "Detected in many" 13 "Hofbauer cells: 216.2;Kupffer cells: 246.9;Langerhans cells: 132.6;Macrophages: 327.1;monocytes: 179.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 1213.7" "Lineage enhanced" "Detected in all" "granulocytes: 1213.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041023, HPA041072" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA041023: AB_10794434, HPA041072: AB_10794262" "unprognostic (7.94e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.18e-2)" "prognostic favorable (1.54e-5)" "unprognostic (3.27e-1)" "unprognostic (4.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-2)" "unprognostic (6.76e-2)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (8.12e-2)" "unprognostic (1.81e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-1)" "unprognostic (2.02e-1)" 2.6 2.3 0.5 13.4 0.6 1.7 1.2 0.8 1.0 1.0 0.7 5.1 1.7 0.4 0.2 0.6 1.1 0.3 0.7 0.6 0.5 0.8 5.5 7.4 3.9 1.0 0.7 0.4 0.9 0.7 0.5 3.3 0.9 0.9 1.5 0.2 2.0 1.6 0.2 0.5 2.7 0.5 0.5 29.8 1.3 0.2 0.6 2.2 0.6 0.9 1.2 2.3 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.5 303.9 46.2 0.7 357.2 0.8 3.8 0.5 0.9 233.9 0.5 0.9 1.2 1213.7 2.7 263.5 55.5 1.0 210.7 0.5 0.6 0.8 1.0 0.6 0.5 1.0 0.7 0.9 0.5 0.6 1.4 1.7 3.2 12.2 0.7 7.1 3.2 0.7 0.0 0.0 1.3 1.4 3.7 4.0 2.8 5.0 1.8 10.4 0.7 15.2 0.0 0.0 0.2 0.4 1.0 1.2 4.0 0.0 6.5 1.1 0.0 1.4 3.2 0.0 2.5 10.1 0.4 2.9 1.8 216.2 0.0 0.8 0.3 0.0 246.9 132.6 0.1 0.9 327.1 8.8 16.9 179.9 0.7 3.1 1.0 0.4 0.0 1.2 0.0 1.3 0.6 0.1 0.4 4.4 2.1 0.0 0.9 1.1 0.1 0.2 0.6 2.0 1.4 5.4 0.2 0.0 0.5 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IRF5 ENSG00000128604 "Interferon regulatory factor 5" Q13568 7 128937457-128950038 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 20.2;Hofbauer cells: 38.4;Kupffer cells: 34.5;Macrophages: 27.8;monocytes: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 17.6;dendritic cells: 43.6;monocytes: 53.1" "Cell line enhanced" "Detected in many" "HDLM-2: 124.3;RPMI-8226: 91.9;THP-1: 50.0;U-937: 62.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA046700, HPA076024" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "HPA046700: AB_2679761, HPA076024: " "unprognostic (4.01e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-1)" "unprognostic (1.57e-2)" "unprognostic (5.69e-3)" "unprognostic (1.49e-1)" "unprognostic (2.74e-1)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" "unprognostic (6.85e-2)" "unprognostic (1.53e-3)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (6.58e-2)" "unprognostic (3.20e-3)" 5.5 3.5 4.8 13.1 3.9 20.6 3.2 4.9 5.2 3.2 3.9 4.4 9.5 1.6 3.0 12.6 4.5 6.3 1.8 4.3 6.4 13.5 5.1 10.6 16.2 8.7 6.3 1.0 5.9 6.4 5.2 3.9 7.4 3.3 3.6 0.5 6.8 12.7 0.8 8.6 11.2 3.1 7.6 24.0 4.6 1.2 7.9 4.2 2.2 1.2 11.8 6.5 5.8 11.3 13.9 4.6 0.0 1.4 0.0 0.0 0.0 0.2 0.1 1.2 0.9 0.3 5.7 10.8 5.2 0.2 12.1 12.9 3.4 2.6 0.3 124.3 2.9 18.3 0.3 1.9 0.0 2.7 25.4 0.0 15.1 0.3 1.8 1.0 0.0 0.1 0.0 31.5 0.0 5.0 0.0 4.8 0.3 1.7 2.6 0.8 0.1 91.9 3.8 8.1 0.4 2.0 2.7 3.0 1.4 0.0 4.8 50.0 0.0 0.0 0.3 0.5 1.2 19.4 13.5 4.5 0.5 62.6 0.3 1.8 42.7 4.2 1.0 53.1 4.0 17.6 2.3 0.8 43.6 15.0 0.1 0.1 2.9 4.9 38.0 10.4 6.2 22.7 4.8 3.9 4.9 5.2 4.3 6.4 8.7 6.3 7.4 7.6 7.9 11.3 0.1 0.0 3.6 0.0 12.7 0.8 0.8 2.2 0.0 0.3 0.8 0.9 0.8 2.8 2.4 20.2 0.0 0.3 7.2 0.8 3.9 3.1 0.2 2.8 0.3 0.9 0.0 6.1 0.4 2.4 0.3 0.3 2.0 2.6 8.8 0.5 0.0 1.2 38.4 0.0 0.3 1.5 0.0 34.5 16.5 0.2 0.0 27.8 0.0 8.4 76.1 0.0 3.1 0.0 0.1 2.3 1.7 0.0 9.3 0.7 4.9 6.2 10.1 0.3 0.0 0.2 0.7 0.1 0.5 2.8 2.0 1.5 3.0 0.0 1.5 2.1 ITGAM "CD11B, CR3A, MAC-1" ENSG00000169896 "Integrin subunit alpha M" P11215 16 31259967-31332892 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Innate immunity" "Integrin, Receptor" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 182.8" "Group enriched" "Detected in many" 4 "dendritic cells: 45.4;granulocytes: 35.5;Hofbauer cells: 47.2;Kupffer cells: 117.7;Langerhans cells: 45.5;Macrophages: 83.2;Microglial cells: 41.2;monocytes: 87.4;NK-cells: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HMC-1: 50.0;NB-4: 19.9;U-937: 22.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002274, CAB025091, CAB072870" Enhanced NA NA 1000000 "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025091: , CAB072870: AB_2665722, HPA002274: AB_1078435" "unprognostic (1.82e-2)" "unprognostic (1.70e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-2)" "unprognostic (2.40e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (3.29e-3)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.93e-5)" "unprognostic (9.89e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (3.99e-2)" "unprognostic (5.03e-2)" 13.4 4.7 3.4 24.7 3.5 182.8 3.0 4.5 4.2 3.3 4.8 3.0 2.2 2.0 0.7 2.6 2.3 5.9 2.9 3.6 5.1 1.0 3.5 16.4 7.4 6.7 5.7 1.6 2.3 1.3 0.1 7.7 7.3 1.5 3.4 0.3 2.4 2.2 1.4 1.7 3.5 11.2 6.5 13.1 3.1 1.4 8.6 5.2 1.0 3.1 10.4 8.0 0.2 10.8 0.8 1.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.5 0.8 1.3 0.9 0.0 0.4 0.1 0.0 0.4 0.0 7.6 0.0 1.0 0.0 0.0 0.0 1.8 50.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.3 0.1 1.0 0.0 2.2 0.0 0.0 0.0 0.5 0.4 0.0 0.2 4.3 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 22.6 0.1 93.3 55.7 70.2 31.1 20.9 1.9 4.8 3.3 9.5 9.5 1.0 0.9 7.7 58.4 54.4 3.2 0.6 1.2 27.0 3.4 3.5 4.5 4.2 3.6 5.1 6.7 5.7 7.3 6.5 8.6 10.8 1.4 3.2 9.8 0.7 9.3 1.1 0.3 1.5 0.0 0.0 1.8 3.8 2.3 4.3 1.8 0.0 0.0 0.3 45.4 0.0 0.0 1.2 0.5 0.3 0.4 1.6 3.6 9.4 1.0 0.0 0.7 1.1 1.1 0.5 35.5 0.5 2.2 1.2 47.2 0.0 1.0 0.1 0.0 117.7 45.5 1.8 0.3 83.2 0.0 41.2 87.4 0.0 75.2 3.0 0.3 0.9 0.0 0.0 4.5 0.5 0.0 0.2 0.9 0.0 13.1 1.2 0.5 0.7 0.9 0.5 1.0 0.8 14.9 0.0 0.3 0.2 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 50.3;Excitatory neurons: 67.8;Hofbauer cells: 63.6;Inhibitory neurons: 49.2;Kupffer cells: 86.2;Macrophages: 51.3;Melanocytes: 64.0;NK-cells: 51.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 278.8;JURKAT: 142.7;U-937: 289.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 12.8 7.7 69.2 28.6 94.1 63.8 8.0 7.4 188.3 5.6 0.0 8.8 5.4 7.2 2.3 5.0 8.6 11.2 22.1 141.6 12.8 26.0 10.1 31.1 43.6 78.7 5.3 5.6 4.0 1.5 20.3 5.9 77.5 6.2 4.6 17.8 6.4 3.4 12.6 12.3 23.9 6.3 1.5 65.8 6.5 5.6 18.9 27.0 6.2 15.8 24.7 8.8 5.1 89.7 11.3 27.0 2.5 4.5 1.5 5.0 10.3 6.3 40.0 6.3 7.8 10.6 4.1 62.0 23.3 6.1 7.7 5.4 2.7 1.0 3.2 84.6 9.6 71.1 25.3 21.1 6.0 278.8 1.9 6.5 1.3 3.4 7.5 6.3 3.6 142.7 2.7 114.2 3.1 9.8 61.9 115.9 1.1 3.9 15.4 13.8 9.7 78.9 0.1 0.2 20.6 6.2 5.3 6.4 101.0 2.7 5.4 117.3 1.1 1.3 9.4 14.4 7.5 84.4 122.4 100.4 12.7 289.2 1.9 4.4 34.3 18.6 29.8 27.2 26.8 7.5 18.2 28.0 31.0 8.7 18.7 20.6 14.4 19.4 25.0 12.7 19.1 43.2 69.2 94.1 7.4 188.3 141.6 12.8 78.7 5.3 77.5 1.5 18.9 89.7 3.0 0.0 6.6 7.5 23.0 4.8 1.7 1.8 1.8 24.0 1.2 2.3 15.7 7.2 1.5 1.8 6.2 0.5 50.3 0.3 0.0 0.3 5.8 3.4 1.9 3.1 0.0 11.1 67.8 1.4 2.3 3.5 2.0 0.6 8.8 2.9 3.9 1.0 63.6 6.7 49.2 0.5 2.0 86.2 19.0 5.2 3.7 51.3 64.0 5.6 26.6 4.9 51.5 8.5 6.1 0.6 0.1 2.6 23.4 0.4 0.1 40.8 8.7 11.8 0.0 2.1 3.1 3.2 2.9 0.7 2.8 0.8 44.3 2.5 0.3 0.6 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.6;parathyroid gland: 6.0;testis: 9.2" "Cell type enriched" "Detected in some" 4 "Microglial cells: 41.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "GAMG: 1.0;RT4: 1.9;SuSa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.3 0.8 1.7 1.7 1.5 0.0 0.2 0.9 1.9 0.1 5.6 0.4 0.5 0.2 1.0 0.2 0.3 0.4 1.6 1.6 1.4 3.9 0.5 0.4 0.6 1.6 2.3 0.1 0.3 6.0 0.3 0.2 1.8 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.5 0.3 1.8 0.6 0.4 9.2 2.2 1.1 1.9 0.0 0.5 0.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.9 0.7 0.2 0.0 0.7 0.5 2.9 0.0 0.7 0.0 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.7 1.5 0.9 1.9 1.6 1.4 1.6 2.3 1.8 1.8 2.2 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 6.3 0.0 0.4 0.0 0.0 6.0 0.0 4.4 0.0 0.0 4.0 8.1 0.6 0.0 3.2 0.0 41.2 9.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.3 0.1 0.1 0.4 0.0 0.1 KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 136.1;Club cells: 109.6;Ionocytes: 114.0;Langerhans cells: 190.5;Macrophages: 122.9;monocytes: 248.0;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cell line enhanced" "Detected in many" "A549: 185.2;GAMG: 298.5;HeLa: 195.5;Hep G2: 128.3;hTEC/SVTERT24-B: 106.5;U-87 MG: 314.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 5.2 4.0 2.4 24.4 2.1 10.8 30.8 2.7 4.5 4.0 3.6 2.4 1.1 2.5 1.3 6.7 1.2 9.8 1.2 2.0 1.6 18.6 88.4 13.5 15.0 2.8 1.7 0.4 0.9 0.8 1.2 7.3 3.3 0.9 2.9 1.5 1.8 0.7 0.7 1.3 3.0 4.8 0.5 8.9 5.8 16.6 6.6 3.9 2.3 0.3 28.9 51.5 3.4 2.1 0.2 185.2 0.3 0.4 0.4 0.6 0.5 0.4 5.1 0.2 0.2 3.3 2.7 11.9 0.5 0.1 298.5 0.7 0.1 0.2 0.2 0.6 0.2 4.3 195.5 128.3 2.4 0.4 0.8 17.3 15.0 106.5 0.6 0.2 0.2 0.3 0.5 1.1 1.7 96.7 0.2 11.8 0.7 0.2 0.9 0.2 0.9 0.4 3.2 96.0 0.5 0.3 102.2 15.2 1.0 1.0 50.9 26.5 1.5 5.9 0.5 89.1 0.3 0.7 0.3 0.3 314.5 22.2 0.6 0.7 109.4 2.4 0.5 142.7 0.4 73.6 0.6 0.3 111.2 51.3 0.5 0.3 5.8 1.8 123.4 77.7 0.6 49.2 2.4 2.1 2.7 4.5 2.0 1.6 2.8 1.7 3.3 0.5 6.6 2.1 3.0 3.2 2.7 0.7 46.8 4.0 0.5 136.1 0.0 0.5 5.8 0.9 1.6 7.2 109.6 3.7 4.2 3.3 16.1 0.7 5.9 14.5 46.3 1.5 1.1 5.1 0.0 2.5 1.3 9.5 2.3 1.8 20.4 15.7 0.0 0.0 2.5 49.1 38.8 10.1 0.9 0.0 114.0 64.7 190.5 42.8 1.8 122.9 1.8 29.0 248.0 0.2 1.0 0.5 0.8 59.6 1.1 0.4 5.1 1.1 0.0 44.4 21.1 0.6 6.6 0.5 3.9 47.8 8.0 1.5 3.1 104.7 2.2 0.1 1.0 22.6 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54637528 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 36.1" "Cell type enhanced" "Detected in some" "B-cells: 32.3;dendritic cells: 37.4;Kupffer cells: 87.3;Macrophages: 73.8;Microglial cells: 30.9;monocytes: 39.6;Plasma cells: 34.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "intermediate monocyte: 39.3;non-classical monocyte: 63.7" "Lineage enriched" "Detected in many" 11 "monocytes: 63.7" "Group enriched" "Detected in some" 19 "Daudi: 5.6;THP-1: 2.9" "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" 2.5 1.6 0.2 7.0 0.2 1.2 1.0 0.2 0.3 0.6 0.2 2.1 0.1 0.4 0.0 0.7 1.5 0.0 0.9 0.2 0.3 1.2 2.2 7.6 5.6 0.6 0.5 0.6 0.7 0.0 0.9 0.1 0.8 1.1 0.4 0.0 1.2 0.2 0.2 0.1 6.0 2.7 0.7 36.1 1.1 0.2 0.7 0.0 0.8 0.0 0.3 2.1 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 8.1 0.0 1.4 39.3 0.0 2.3 0.0 1.2 5.6 2.4 0.0 0.8 0.2 0.0 63.7 2.2 0.0 5.5 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.5 0.8 0.7 0.7 1.4 0.9 0.0 2.2 0.0 32.3 0.3 0.3 0.0 0.0 0.0 0.3 0.8 1.0 1.5 2.5 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.3 0.0 0.0 2.0 0.0 1.3 0.0 0.0 0.1 0.2 0.5 0.0 2.5 0.0 2.5 0.7 15.9 0.0 0.1 0.0 0.0 87.3 2.2 0.0 0.0 73.8 0.0 30.9 39.6 0.3 9.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.1 2.2 LILRB2 "CD85d, ILT4, LIR-2, LIR2, MIR-10, MIR10" ENSG00000131042 "Leukocyte immunoglobulin like receptor B2" Q8N423 19 54273812-54281184 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 35.0;lung: 15.0;lymphoid tissue: 51.2" "Cell type enhanced" "Detected in some" "Kupffer cells: 150.7;Langerhans cells: 61.8;Macrophages: 147.3;monocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "classical monocyte: 61.6;intermediate monocyte: 132.3;neutrophil: 62.9;non-classical monocyte: 153.4" "Group enriched" "Detected in many" 6 "granulocytes: 62.9;monocytes: 153.4" "Not detected" "Not detected" NA NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (1.23e-1)" "unprognostic (1.12e-2)" "unprognostic (3.21e-2)" "unprognostic (3.51e-2)" "unprognostic (6.21e-3)" "unprognostic (1.70e-2)" "unprognostic (1.44e-2)" "unprognostic (2.94e-1)" "unprognostic (1.08e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.45e-7)" "unprognostic (1.90e-2)" "unprognostic (4.68e-3)" "unprognostic (3.72e-1)" "unprognostic (9.73e-2)" 6.5 2.6 0.0 12.2 0.0 35.0 2.2 0.0 0.5 1.1 0.6 2.3 3.2 1.2 0.1 1.0 3.7 0.0 2.5 0.1 0.1 2.2 3.9 15.0 0.8 0.9 0.5 0.8 1.3 0.0 1.3 0.5 0.6 1.7 0.8 0.0 1.6 0.4 0.6 0.6 3.0 0.4 0.0 51.2 1.8 0.3 1.0 0.2 1.1 0.1 0.0 2.3 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.0 61.6 16.2 0.1 132.3 0.3 0.0 0.0 0.0 18.8 0.1 0.1 0.0 62.9 0.0 153.4 8.0 0.3 29.7 0.0 0.0 0.0 0.5 0.1 0.1 0.9 0.5 0.6 0.0 1.0 0.2 0.5 3.2 10.9 0.0 5.5 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 1.5 3.1 0.0 0.0 0.1 10.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.3 1.0 1.1 0.0 5.1 0.0 2.2 1.5 27.2 0.0 0.0 0.0 0.0 150.7 61.8 0.1 0.0 147.3 3.6 1.0 75.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.3 2.2 0.0 6.6 0.4 0.2 0.0 0.0 0.0 0.6 0.1 2.9 0.0 0.0 0.1 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LYVE1 "LYVE-1, XLKD1" ENSG00000133800 "Lymphatic vessel endothelial hyaluronan receptor 1" Q9Y5Y7 11 10556966-10611689 "Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 126.4;placenta: 149.3" "Group enriched" "Detected in many" 4 "Hepatic stellate cells: 238.8;Hofbauer cells: 807.4;Kupffer cells: 338.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "HUVEC TERT2: 81.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.8" "CAB025860, HPA042953" Supported NA NA 3300000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "CAB025860: , HPA042953: AB_2678238" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "unprognostic (1.87e-1)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.53e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (6.98e-5)" "unprognostic (1.67e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-3)" 126.4 68.9 2.7 19.3 3.5 0.9 37.3 2.0 5.1 17.6 8.9 19.9 13.3 8.1 5.7 26.2 23.0 20.2 13.5 2.9 2.4 8.1 44.2 23.8 8.4 3.0 2.2 11.8 4.9 2.3 2.7 149.3 3.1 4.0 20.0 0.3 5.4 11.2 5.0 7.1 17.6 67.1 2.1 61.6 10.5 4.3 3.3 1.7 13.5 27.4 3.0 35.1 6.8 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 81.6 0.0 7.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 3.5 2.0 5.1 2.9 2.4 3.0 2.2 3.1 2.1 3.3 3.2 5.7 0.0 2.8 8.1 2.1 3.7 0.1 0.0 0.0 0.0 0.5 0.3 4.6 8.6 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 1.0 0.0 0.2 102.7 0.0 5.3 0.8 0.0 5.7 3.4 0.0 0.0 1.3 0.0 238.8 4.5 807.4 0.0 0.4 0.0 0.0 338.1 10.7 2.3 3.7 86.0 7.2 12.2 0.1 0.0 0.0 0.5 0.6 0.0 0.0 0.4 2.7 0.2 0.0 0.0 1.5 0.0 13.1 3.4 6.8 0.0 0.0 1.4 3.3 11.1 1.4 0.7 0.0 0.2 LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10588.1;salivary gland: 21115.5;stomach 1: 8941.1" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3106.1;Kupffer cells: 2841.2;Langerhans cells: 4859.1;Macrophages: 4870.7;monocytes: 7063.0;Pancreatic endocrine cells: 3152.5" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25266.2;myeloid DC: 14438.7" "Group enriched" "Detected in all" 20 "dendritic cells: 14438.7;monocytes: 25266.2" "Cell line enriched" "Detected in many" 13 "OE19: 12130.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1500000000 1500000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" 95.8 27.8 3.5 802.1 4.0 10588.1 128.2 3.7 18.5 156.2 11.4 309.0 3605.0 65.7 4.2 106.3 33.9 1054.6 34.8 2.6 4.3 32.4 138.0 1355.2 739.7 8.0 7.3 20.4 63.1 13.8 7.2 91.3 12.2 40.2 273.8 4.4 21115.5 21.8 34.0 58.7 1322.2 123.9 5.4 621.0 8941.1 21.8 10.9 321.8 27.8 36.4 652.8 428.5 16.2 11.7 0.6 0.1 0.0 0.2 0.0 0.0 4.8 0.0 0.0 0.0 0.3 9.5 6.5 4.2 1.5 0.0 3.6 1.2 0.0 0.0 0.2 1.2 0.1 62.4 1.0 960.4 0.0 110.6 50.5 0.0 0.1 0.0 0.0 0.2 0.0 0.3 7.7 0.3 0.0 0.2 2.6 109.5 2.3 12130.8 0.2 1.6 1.4 16.7 0.3 0.5 0.8 3.6 0.5 0.1 0.5 0.7 0.0 489.0 0.6 0.0 2.6 2.3 0.9 2.6 1.1 1.2 0.1 518.5 0.0 443.4 25266.2 298.2 32.6 4798.4 52.3 100.5 20.1 22.7 14438.7 20.8 20.0 17.8 1007.7 108.1 880.1 301.2 31.1 25392.1 3.5 4.0 3.7 18.5 2.6 4.3 8.0 7.3 12.2 5.4 10.9 11.7 24.0 86.6 285.8 0.0 80.8 57.2 1.7 1.2 1.2 0.3 1205.7 32.3 0.2 734.9 51.1 27.6 0.0 5.6 39.6 32.1 0.0 55.1 1.9 2.6 1.9 25.1 12.5 264.6 0.2 547.3 9.4 26.8 3106.1 2.9 123.6 0.5 29.6 25.4 887.1 0.0 0.2 112.4 0.0 2841.2 4859.1 17.4 4.1 4870.7 53.4 0.0 7063.0 0.1 176.1 0.0 0.3 3152.5 600.5 2.2 9.0 2.7 41.8 6.6 33.8 1.0 39.5 7.4 9.9 0.7 3.9 1.5 38.2 8.5 50.6 0.3 111.4 38.3 MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 273.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 264.0;Hofbauer cells: 377.6;Kupffer cells: 672.8;Macrophages: 456.7;Squamous epithelial cells: 361.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.4" "Lineage enriched" "Detected in many" 15 "monocytes: 121.4" "Cell line enhanced" "Detected in some" "HSkMC: 28.6;hTCEpi: 61.2;SCLC-21H: 16.7;SiHa: 15.6;U-138 MG: 16.4;U-2197: 24.4;U-87 MG: 16.0" "Low region specificity" "Detected in many" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" 35.3 13.8 4.8 37.3 4.9 59.2 27.3 4.4 10.5 16.5 6.9 9.5 7.8 9.3 5.4 33.0 11.3 24.4 10.7 3.7 5.7 17.5 29.3 20.9 27.8 14.3 6.3 6.8 15.8 273.1 3.1 13.2 7.2 8.3 7.2 0.6 18.3 4.7 15.8 85.3 13.2 14.2 9.0 96.3 11.0 3.9 13.1 6.7 50.1 16.7 12.7 13.9 21.9 15.8 0.0 0.0 0.0 2.6 1.5 0.2 0.4 0.3 0.1 0.3 0.1 0.4 0.2 0.0 1.9 0.4 0.0 3.8 0.0 0.0 0.0 0.0 1.4 0.0 1.2 0.2 0.9 0.0 0.1 28.6 61.2 0.2 2.1 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.3 7.4 2.6 6.2 0.0 0.0 0.0 0.0 0.5 0.4 16.7 1.4 15.6 1.5 3.9 5.4 1.5 0.3 0.5 16.4 0.3 24.4 0.0 0.0 0.0 0.0 16.0 0.6 0.0 0.4 24.3 0.0 0.0 88.3 0.0 0.0 0.0 0.1 7.9 0.1 0.0 0.0 2.1 0.0 121.4 0.1 0.0 10.6 4.8 4.9 4.4 10.5 3.7 5.7 14.3 6.3 7.2 9.0 13.1 15.8 70.0 22.4 37.9 1.6 7.8 68.6 50.5 17.1 264.0 12.0 112.2 217.8 208.9 7.2 16.8 51.5 25.0 9.8 7.6 117.1 1.9 2.3 0.8 15.7 64.4 39.1 57.7 4.0 0.8 3.4 2.8 172.7 49.5 27.6 10.8 0.9 34.6 36.1 377.6 3.3 25.4 50.7 6.1 672.8 91.7 2.8 29.5 456.7 21.4 6.5 65.3 21.9 3.1 2.0 1.3 4.9 30.9 24.5 5.6 29.7 89.5 1.3 2.4 8.3 13.1 160.6 102.4 0.8 1.7 361.5 88.2 12.4 9.5 114.6 39.0 19.2 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 NCF2 "NOXA2, p67phox" ENSG00000116701 "Neutrophil cytosolic factor 2" P19878 1 183555562-183590876 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.9;lung: 74.6;lymphoid tissue: 78.8" "Group enriched" "Detected in many" 5 "Ductal cells: 68.6;Hofbauer cells: 212.0;Kupffer cells: 137.9;Langerhans cells: 129.5;Macrophages: 194.4;monocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1313.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 26.4;HMC-1: 21.4;hTERT-HME1: 51.6;RPMI-8226: 20.0;U-2 OS: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002327, HPA006040, CAB022160" Enhanced Supported Cytosol NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB022160: , HPA002327: AB_1079550, HPA006040: AB_1854906" "unprognostic (4.97e-2)" "unprognostic (3.48e-2)" "unprognostic (2.40e-2)" "unprognostic (1.22e-3)" "unprognostic (5.83e-3)" "unprognostic (4.04e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.29e-1)" "unprognostic (2.45e-1)" "unprognostic (2.33e-1)" "unprognostic (5.70e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.24e-2)" "unprognostic (2.36e-2)" 29.9 5.8 2.7 76.9 3.0 191.9 7.0 3.2 14.6 9.5 4.5 10.4 8.5 4.1 1.6 7.6 8.0 23.8 5.6 2.3 3.9 3.7 12.7 74.6 17.3 6.2 4.2 2.1 4.6 2.8 2.7 39.7 6.8 2.9 12.5 0.8 6.6 3.5 3.7 15.9 12.4 20.4 4.5 78.8 5.8 2.1 12.0 11.3 3.0 11.5 16.9 24.2 5.9 7.8 26.4 0.8 0.0 0.0 0.0 0.0 0.3 1.9 2.4 3.4 1.6 0.2 0.8 3.2 4.3 0.8 0.6 14.3 0.1 19.0 3.1 16.2 0.0 0.0 7.3 6.0 0.0 2.0 21.4 0.0 4.1 3.4 51.6 2.2 0.0 0.1 0.0 5.6 5.8 0.2 0.2 1.1 0.4 1.5 1.5 7.0 2.2 20.0 0.8 0.2 0.0 0.1 0.3 0.1 0.9 1.7 2.8 9.1 1.2 0.1 50.2 0.0 4.9 0.9 1.4 0.6 0.4 10.3 0.0 199.5 489.2 1313.6 1.0 348.8 1.6 14.1 4.0 1.6 246.0 10.8 2.2 1.3 799.7 2.1 326.1 13.5 11.1 298.9 2.7 3.0 3.2 14.6 2.3 3.9 6.2 4.2 6.8 4.5 12.0 7.8 0.7 9.6 15.7 0.0 8.4 5.5 0.2 13.7 1.8 0.3 0.1 0.3 1.3 7.2 17.3 0.0 0.0 1.0 9.6 0.1 3.9 68.6 1.1 1.9 0.5 3.5 0.0 1.7 0.3 3.9 1.1 2.0 0.5 1.3 7.6 0.0 3.3 1.0 212.0 0.0 0.3 0.2 26.4 137.9 129.5 2.9 0.6 194.4 7.2 3.7 223.6 0.0 6.2 0.0 0.2 27.3 2.6 0.0 3.2 0.6 0.0 0.3 32.0 0.7 13.1 0.7 6.8 0.1 0.6 0.6 4.3 1.9 3.7 0.2 0.0 1.2 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.1;lymphoid tissue: 36.9" "Group enriched" "Detected in some" 9 "Kupffer cells: 124.4;Macrophages: 53.2;Microglial cells: 66.5;monocytes: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 581.5" "Group enriched" "Detected in many" 6 "granulocytes: 581.5;monocytes: 185.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" 4.8 3.8 1.6 20.6 1.6 25.1 4.2 1.6 2.2 2.6 2.7 4.5 4.6 1.9 0.8 3.2 3.1 3.9 1.4 1.9 2.0 1.6 8.2 7.6 18.2 3.1 2.4 1.6 1.2 1.6 0.5 3.3 2.8 1.4 6.2 0.1 2.9 3.2 0.7 2.1 11.0 5.3 3.7 36.9 3.1 0.7 4.2 4.5 1.3 3.8 8.4 4.1 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 152.5 137.2 0.3 155.4 0.3 1.5 0.2 0.2 66.4 0.6 0.2 0.3 581.5 0.1 185.6 1.1 0.2 77.6 1.6 1.6 1.6 2.2 1.9 2.0 3.1 2.4 2.8 3.7 4.2 4.0 0.9 0.0 6.1 0.0 1.3 0.0 0.1 0.0 0.0 0.8 0.6 0.6 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 3.6 0.3 0.0 0.2 0.6 0.5 0.0 2.5 0.0 0.7 0.4 7.7 1.7 0.2 0.0 0.0 124.4 4.5 0.0 0.0 53.2 0.0 66.5 63.3 1.1 2.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 0.0 PEAK3 "C19orf35, FLJ45778" ENSG00000188305 "PEAK family member 3" Q6ZS72 19 2274631-2282175 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 4.1" "Cell type enhanced" "Detected in some" "dendritic cells: 1.5;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 41.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 41.0" "Cell line enriched" "Detected in some" 9 "HMC-1: 12.2" "Group enriched" "Detected in some" 5 "basal ganglia: 6.7;cerebellum: 3.1" HPA057806 Uncertain Uncertain Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "HPA057806: AB_2683534" "unprognostic (9.42e-2)" "unprognostic (3.26e-2)" "unprognostic (7.27e-2)" "unprognostic (6.23e-2)" "unprognostic (2.65e-2)" "unprognostic (8.40e-3)" "unprognostic (3.67e-1)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (2.08e-1)" "unprognostic (6.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-2)" "unprognostic (3.20e-2)" "unprognostic (1.90e-1)" 0.5 0.4 0.5 1.3 0.9 2.3 0.3 0.5 1.6 0.2 0.1 0.4 0.2 0.2 0.0 0.2 0.5 0.2 0.7 0.4 0.5 0.3 0.2 1.1 0.4 1.4 1.0 0.1 0.2 0.0 0.2 0.1 1.0 0.3 0.2 0.0 0.2 0.0 0.3 0.3 0.8 0.1 0.9 4.1 0.3 0.1 0.8 0.1 0.2 0.0 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.4 0.0 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 10.5 4.4 11.7 1.6 5.7 0.2 0.2 0.1 0.2 1.8 0.4 0.1 0.3 41.0 4.5 1.9 0.2 0.0 1.1 0.5 0.9 0.5 1.6 0.4 0.5 1.4 1.0 1.0 0.9 0.8 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 1640.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.1;eosinophil: 29.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 220.8;BEWO: 186.8;HHSteC: 233.2;HSkMC: 302.2;U-87 MG: 326.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" NA NA 9720000000 210000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" 437.9 188.9 107.9 80.5 109.8 20.7 122.6 100.8 142.0 155.4 197.6 76.9 41.6 114.9 72.6 62.0 173.5 182.3 123.4 100.4 119.0 198.9 29.5 97.1 61.3 119.5 152.2 159.5 296.9 22.1 38.5 428.8 126.0 50.7 42.4 4.8 132.1 71.5 24.0 68.0 71.6 181.9 124.7 57.6 89.7 32.3 114.5 229.9 44.4 20.8 21.1 339.7 113.1 118.1 13.8 1.9 94.9 0.1 220.8 66.8 186.8 5.3 16.3 18.5 11.0 78.7 15.9 3.5 151.6 23.6 0.4 154.7 29.2 0.6 8.4 1.8 0.2 28.8 3.3 37.7 233.2 0.0 35.5 302.2 7.7 49.1 0.9 74.1 41.3 3.2 9.5 44.9 6.2 3.9 3.2 123.1 16.9 12.5 74.5 1.3 0.1 1.7 0.5 0.0 10.1 35.4 3.7 110.3 160.9 15.7 1.5 117.2 9.0 46.2 1.1 24.2 0.8 19.7 5.3 5.4 326.4 34.3 7.8 33.1 2.7 29.7 1.6 7.1 1.2 8.7 0.4 1.6 2.5 3.2 0.0 1.0 1.4 4.9 12.6 17.5 0.8 2.7 107.9 109.8 100.8 142.0 100.4 119.0 119.5 152.2 126.0 124.7 114.5 118.1 21.9 0.0 2.3 30.3 3.8 40.7 34.9 53.0 33.0 0.4 9.5 22.6 1.5 5.7 9.6 27.6 0.0 14.8 3.5 0.5 1.9 3.4 16.3 54.6 36.9 27.9 0.0 9.0 0.8 103.2 97.7 256.8 3.6 5.7 0.0 23.4 121.1 2.8 1640.3 3.3 1.4 1.2 12.2 254.0 40.9 24.9 307.9 71.8 35.6 4.7 3.8 13.8 7.2 0.5 0.2 9.9 0.0 199.0 11.8 15.7 0.0 18.2 70.8 1.1 32.9 16.1 35.6 5.7 7.3 24.0 35.8 31.7 3.3 99.5 0.7 18.4 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 RAB39A RAB39 ENSG00000179331 "RAB39A, member RAS oncogene family" Q14964 11 107928448-107963482 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;lymphoid tissue: 3.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 5.2;Inhibitory neurons: 8.8;Microglial cells: 20.6;Spermatocytes: 6.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 11.6;NTERA-2: 8.6;RPMI-8226: 15.5;SCLC-21H: 27.8;SH-SY5Y: 17.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042505 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042505: AB_2678030" "unprognostic (1.45e-1)" "unprognostic (1.48e-2)" "unprognostic (1.83e-1)" "unprognostic (3.40e-2)" "unprognostic (4.99e-1)" "unprognostic (4.30e-2)" "unprognostic (4.26e-3)" "unprognostic (1.20e-1)" "unprognostic (5.55e-2)" "unprognostic (7.36e-2)" "unprognostic (4.22e-3)" "unprognostic (2.24e-2)" "unprognostic (1.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (5.02e-2)" "unprognostic (2.43e-1)" 0.7 0.9 1.7 2.9 1.4 0.6 0.3 3.1 3.2 0.2 0.2 0.5 0.5 0.2 0.0 0.3 0.2 0.8 0.2 3.2 3.9 0.6 0.6 0.9 2.1 3.1 2.6 0.2 0.3 0.2 0.4 1.2 3.5 0.2 0.8 1.1 0.2 0.1 0.0 0.3 0.7 0.7 2.6 3.0 0.6 0.8 2.2 2.6 0.3 0.1 1.4 0.9 0.0 2.3 0.0 1.8 7.3 0.1 0.0 0.0 0.9 0.1 0.0 0.8 0.6 0.0 0.0 0.4 0.1 0.0 11.6 0.0 7.4 0.0 0.1 0.0 0.9 0.1 0.1 0.0 0.0 0.5 6.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.2 0.0 4.0 15.5 0.1 0.0 27.8 17.1 0.0 0.0 0.4 1.6 0.4 3.0 0.0 0.1 1.9 0.0 1.3 0.1 4.3 0.0 0.4 1.7 4.1 0.1 1.4 0.0 0.0 2.2 0.0 0.8 0.0 0.0 1.0 0.5 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.4 1.7 1.4 3.1 3.2 3.2 3.9 3.1 2.6 3.5 2.6 2.2 2.3 0.0 0.0 1.1 0.7 0.8 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 1.8 0.0 5.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 8.8 0.0 0.0 4.1 3.7 0.8 0.0 4.1 0.0 20.6 1.8 0.0 0.0 4.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.1 6.4 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RENBP "RBP, RNBP" ENSG00000102032 "Renin binding protein" P51606 X 153935269-153944687 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 43.0;lymphoid tissue: 67.0" "Cell type enhanced" "Detected in many" "granulocytes: 127.7;Hofbauer cells: 183.4;Kupffer cells: 70.7;Proximal tubular cells: 204.2" "Cancer enhanced" "Detected in all" "melanoma: 57.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "granulocytes: 2.7;monocytes: 1.6" "Cell line enhanced" "Detected in many" "EFO-21: 35.5;HMC-1: 121.4;SK-MEL-30: 86.4;U-266/84: 74.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000428, HPA000522" Enhanced NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000428: AB_1079799, HPA000522: AB_1079798" "unprognostic (3.08e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (8.83e-3)" "unprognostic (1.85e-1)" "unprognostic (5.22e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (1.15e-1)" "unprognostic (6.47e-3)" "unprognostic (1.99e-1)" "prognostic favorable (3.08e-5)" "unprognostic (2.39e-2)" "unprognostic (6.57e-2)" "unprognostic (4.25e-2)" "unprognostic (8.51e-2)" 22.2 19.2 14.6 13.5 18.2 10.9 11.1 16.0 20.6 5.0 12.3 13.8 8.4 3.9 2.5 2.9 5.6 6.2 11.5 14.6 18.8 43.0 5.3 24.6 16.5 18.4 19.8 1.7 1.8 2.1 6.0 10.3 18.0 3.8 4.2 2.2 5.8 2.0 2.2 9.7 13.9 4.7 15.2 67.0 5.9 1.2 19.4 6.2 5.4 0.1 6.3 6.2 4.5 19.6 0.0 0.0 3.3 0.1 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 35.5 0.0 0.1 0.0 7.1 0.0 0.0 0.0 1.5 28.2 0.0 2.3 20.4 0.0 121.4 0.8 0.0 0.0 0.0 0.0 0.0 1.0 8.2 10.3 0.0 0.6 7.5 0.3 0.4 0.3 0.0 13.6 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 86.4 3.0 0.3 9.9 1.3 0.0 0.8 0.0 0.1 12.5 74.8 5.0 2.5 13.3 9.8 1.7 0.9 2.7 0.1 0.7 0.1 0.4 0.0 0.0 0.1 0.2 0.4 0.2 2.0 0.1 1.6 0.3 0.0 0.5 14.6 18.2 16.0 20.6 14.6 18.8 18.4 19.8 18.0 15.2 19.4 19.6 1.9 0.0 2.2 7.2 8.0 4.7 1.3 0.3 0.6 2.4 0.4 0.6 1.0 2.8 0.4 9.2 0.0 1.3 2.6 0.4 37.2 1.4 0.1 0.1 0.5 10.7 1.8 3.0 0.2 0.4 6.0 4.5 0.0 0.3 127.7 1.3 52.1 0.8 183.4 15.2 1.7 1.0 0.0 70.7 13.3 0.4 0.3 49.2 28.4 6.5 40.7 10.7 8.2 0.5 6.2 0.5 5.3 0.4 4.0 1.4 12.3 204.2 0.2 0.8 13.1 2.2 4.9 0.1 1.4 0.4 2.0 2.9 7.5 0.7 0.7 0.6 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" 43.1 46.7 27.8 40.3 32.8 51.5 40.7 31.9 31.2 40.5 38.8 76.0 75.7 36.9 36.9 103.4 47.4 35.4 32.4 26.1 29.8 44.9 42.0 49.6 47.9 40.7 30.9 26.5 54.5 85.6 29.4 48.9 36.7 35.5 72.7 4.7 92.7 32.4 34.2 68.3 80.1 33.6 33.6 66.8 64.9 36.2 33.3 33.0 38.3 18.9 53.4 38.1 49.4 35.4 44.7 57.3 24.2 37.6 72.0 37.2 72.0 45.0 56.6 46.9 50.1 83.0 102.6 36.5 57.8 68.1 67.7 157.8 72.3 55.9 19.4 145.8 71.1 92.8 31.2 57.6 54.3 48.0 170.9 48.0 97.6 44.4 32.0 37.0 46.0 42.0 31.3 67.5 33.3 68.1 24.6 55.3 24.1 111.0 36.6 42.6 22.3 126.4 54.0 63.1 24.9 25.0 36.7 64.3 42.4 35.4 88.5 76.3 43.4 40.2 23.9 43.8 53.0 46.1 73.2 37.6 37.8 112.2 30.2 118.3 111.3 90.0 94.1 106.9 76.1 80.8 85.3 95.9 81.8 70.9 69.4 75.8 74.4 83.8 119.3 128.7 105.3 120.8 27.8 32.8 31.9 31.2 26.1 29.8 40.7 30.9 36.7 33.6 33.3 35.4 36.0 73.7 31.7 17.9 49.5 17.5 41.7 40.5 19.4 6.8 28.0 24.8 14.4 24.3 53.1 40.5 2.1 156.9 63.4 116.8 15.6 67.4 132.3 30.8 22.0 36.2 37.3 29.0 7.7 92.8 61.9 37.2 54.0 40.6 79.2 31.3 26.4 27.7 164.7 6.7 6.1 77.5 42.7 78.3 44.5 56.2 32.0 77.0 32.0 21.5 56.9 41.4 63.8 12.1 17.9 96.1 75.5 23.0 73.1 54.0 105.7 48.1 52.6 8.4 26.3 25.6 35.8 47.1 35.3 39.6 22.3 136.4 55.1 40.0 64.2 58.5 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SLAMF8 "BLAME, CD353, SBBI42" ENSG00000158714 "SLAM family member 8" Q9P0V8 1 159826811-159837492 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 9 "Hofbauer cells: 36.9;Kupffer cells: 19.8;Langerhans cells: 61.8;Macrophages: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 14.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.7;HL-60: 1.4;U-138 MG: 1.9;U-87 MG: 1.0;U-937: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067601 Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA067601: AB_2685870" "unprognostic (1.04e-1)" "unprognostic (8.80e-3)" "unprognostic (5.12e-2)" "unprognostic (2.14e-3)" "unprognostic (3.07e-2)" "unprognostic (3.22e-2)" "unprognostic (7.87e-2)" "unprognostic (4.29e-1)" "unprognostic (2.20e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.50e-1)" "unprognostic (4.42e-2)" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" 6.9 3.7 1.7 29.8 1.8 0.9 3.0 1.8 3.6 3.8 2.9 7.6 6.6 1.5 0.7 4.2 2.8 8.0 2.6 1.4 2.3 3.9 3.3 16.1 32.9 4.9 3.9 2.8 2.1 0.6 3.5 5.5 5.3 2.5 9.5 0.3 3.4 1.4 0.9 2.8 9.3 7.6 2.5 11.7 4.9 0.8 9.2 10.5 3.0 0.6 17.7 10.3 2.1 4.9 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 1.9 0.0 0.0 0.3 0.0 0.0 0.0 1.0 1.2 0.0 0.0 5.8 0.0 3.5 8.0 0.2 0.0 1.2 4.6 14.3 0.0 0.2 2.7 0.5 8.8 0.5 0.1 0.0 3.1 1.7 1.8 1.8 3.6 1.4 2.3 4.9 3.9 5.3 2.5 9.2 4.9 0.3 0.0 2.3 0.0 1.0 1.8 0.0 0.0 0.0 0.4 0.1 0.4 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.3 0.1 0.8 0.0 0.4 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.2 36.9 0.0 0.1 0.0 0.0 19.8 61.8 0.0 0.3 41.1 0.0 1.0 1.3 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 2.9 0.1 0.0 0.0 1.0 0.5 1.3 0.0 0.0 0.0 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 216.3" "Cell type enhanced" "Detected in all" "B-cells: 338.4;dendritic cells: 258.0;Kupffer cells: 284.4;Macrophages: 256.8;monocytes: 291.7;Plasma cells: 224.4;T-cells: 199.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 177.1;THP-1: 302.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" 65.3 24.0 44.2 136.7 50.7 80.9 33.3 35.7 54.3 43.9 33.8 33.5 17.5 17.9 14.1 26.2 30.7 46.3 17.2 52.1 48.2 19.2 73.5 58.4 205.8 41.8 41.1 17.1 23.8 27.4 43.9 38.0 42.9 20.0 32.1 48.5 29.5 19.0 30.0 33.3 99.2 40.1 38.3 216.3 41.8 17.0 48.0 158.3 19.2 21.2 199.5 52.2 19.3 47.2 25.1 9.3 22.0 22.2 31.4 60.0 12.2 38.4 34.7 38.9 37.9 11.7 16.8 93.1 18.4 34.4 16.0 10.2 41.1 29.4 53.3 177.1 34.8 51.7 14.2 25.5 28.1 54.3 153.7 51.7 24.3 50.4 21.6 19.1 22.4 71.6 94.9 95.2 47.0 16.8 79.3 51.2 13.4 24.7 84.7 30.3 20.4 96.3 18.9 28.9 37.1 17.1 18.1 46.1 29.9 16.8 14.8 302.3 12.4 42.8 17.6 40.2 29.9 31.3 37.1 75.9 38.8 53.1 28.2 12.4 87.7 102.0 14.5 153.8 18.2 43.7 23.3 22.1 49.3 58.6 32.4 30.1 195.4 31.6 195.8 9.3 35.5 52.1 44.2 50.7 35.7 54.3 52.1 48.2 41.8 41.1 42.9 38.3 48.0 47.2 12.8 25.6 28.4 10.1 338.4 18.0 11.4 8.5 4.0 34.7 17.5 13.6 15.3 30.0 24.5 7.3 22.9 5.5 258.0 11.0 5.9 12.6 12.7 78.2 15.8 18.7 9.5 66.7 75.7 18.7 9.6 17.1 26.0 25.0 28.4 10.4 38.6 66.3 43.5 26.9 52.4 9.8 12.2 284.4 140.1 19.5 5.3 256.8 28.4 89.9 291.7 15.0 129.8 54.8 33.6 17.1 8.9 4.9 224.4 9.6 10.0 9.1 70.2 25.6 32.9 12.8 27.9 15.9 11.6 12.7 17.8 4.1 199.9 14.6 9.5 14.6 SNX20 "SLIC-1, SLIC1" ENSG00000167208 "Sorting nexin 20" Q7Z614 16 50666300-50681353 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.0;lymphoid tissue: 33.2" "Cell type enhanced" "Detected in some" "B-cells: 15.3;Cardiomyocytes: 16.4;dendritic cells: 23.7;Hofbauer cells: 17.6;Kupffer cells: 17.2;Langerhans cells: 25.2;Macrophages: 19.3;monocytes: 26.1;NK-cells: 24.7;T-cells: 21.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 29.7;HMC-1: 78.5;NB-4: 48.0;RPMI-8226: 20.6;THP-1: 21.3;U-266/70: 25.7;U-937: 28.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043649 Uncertain Uncertain Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA043649: AB_10965697" "unprognostic (1.53e-2)" "prognostic favorable (9.07e-4)" "unprognostic (5.58e-2)" "unprognostic (5.06e-3)" "unprognostic (9.03e-2)" "prognostic favorable (6.56e-4)" "unprognostic (1.97e-1)" "unprognostic (1.26e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (6.00e-6)" "unprognostic (3.24e-1)" "unprognostic (3.37e-2)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" 2.3 1.0 1.5 20.0 1.5 18.0 1.1 1.8 1.7 1.1 1.5 2.7 2.9 1.0 0.6 1.6 1.0 4.0 0.8 1.3 1.8 0.8 2.2 7.7 27.8 3.4 2.1 0.6 0.5 0.4 0.5 2.7 2.5 1.1 3.6 0.3 1.9 0.7 0.8 2.4 6.1 2.7 2.1 19.2 3.7 0.5 2.6 33.2 0.9 1.1 27.0 6.1 0.7 2.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.7 0.0 5.2 0.0 0.0 0.0 7.4 78.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 48.0 0.0 0.0 0.0 2.4 0.2 20.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.2 0.0 0.0 0.1 0.0 25.7 14.3 6.5 0.0 28.4 0.0 306.6 66.9 208.0 41.6 118.3 52.2 22.6 73.8 50.9 123.4 22.6 56.1 38.9 62.3 51.3 147.5 34.3 137.5 81.8 1.5 1.5 1.8 1.7 1.3 1.8 3.4 2.1 2.5 2.1 2.6 2.9 0.2 0.0 0.0 0.3 15.3 0.8 0.0 0.0 0.0 0.2 0.3 0.6 16.4 2.8 1.3 0.0 0.0 0.1 23.7 0.0 0.0 0.0 0.1 0.3 0.1 1.5 0.0 6.5 0.0 0.0 0.2 0.5 0.5 0.1 5.1 0.0 1.1 0.4 17.6 1.7 0.0 0.0 0.0 17.2 25.2 0.0 0.0 19.3 0.0 0.0 26.1 0.1 24.7 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.1 0.0 0.1 13.1 0.5 0.5 0.2 0.1 0.0 0.6 0.4 21.3 0.1 0.2 0.0 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 THEMIS2 "C1orf38, ICB-1" ENSG00000130775 "Thymocyte selection associated family member 2" Q5TEJ8 1 27872543-27886685 "Predicted intracellular proteins" "Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 215.5;lymphoid tissue: 126.0" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Hofbauer cells: 62.6;Kupffer cells: 135.9;Langerhans cells: 59.9;Macrophages: 125.4;monocytes: 144.8;Plasma cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 403.3;eosinophil: 341.0;intermediate monocyte: 441.4;myeloid DC: 309.6;neutrophil: 498.1;non-classical monocyte: 454.6;plasmacytoid DC: 125.2" "Group enriched" "Detected in all" 6 "dendritic cells: 309.6;granulocytes: 498.1;monocytes: 454.6" "Cell line enhanced" "Detected in many" "Karpas-707: 135.9;U-266/70: 98.4;U-937: 62.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027513, HPA031096" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027513: , HPA031096: AB_10599254" "unprognostic (7.38e-2)" "unprognostic (6.56e-2)" "unprognostic (5.07e-2)" "unprognostic (1.99e-3)" "unprognostic (4.51e-2)" "unprognostic (5.56e-3)" "unprognostic (4.13e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-2)" "unprognostic (3.05e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-2)" "unprognostic (7.21e-3)" "unprognostic (5.07e-2)" "unprognostic (1.42e-2)" "unprognostic (2.24e-3)" "unprognostic (4.52e-3)" 30.7 10.6 10.8 72.8 13.1 215.5 12.7 13.6 14.4 7.2 12.3 14.7 10.1 5.7 3.9 8.0 10.2 23.6 6.6 11.2 16.6 9.2 19.1 45.8 47.9 22.2 14.3 3.3 5.4 2.7 4.9 18.8 19.1 5.4 10.1 0.9 11.1 3.9 3.4 4.5 28.2 15.5 15.4 126.0 12.2 22.4 17.8 16.0 11.0 4.5 29.9 26.9 6.4 24.6 9.1 0.3 3.4 0.5 11.4 15.6 1.5 1.9 20.0 28.7 40.2 1.3 2.4 12.8 1.2 6.6 15.9 1.3 5.2 1.2 4.6 1.7 1.2 18.0 0.4 2.3 22.3 23.0 27.8 7.9 0.3 14.8 0.1 1.5 11.1 1.0 24.7 135.9 2.1 6.1 0.9 20.1 11.8 0.3 1.8 4.1 12.8 23.2 8.6 0.3 0.2 5.0 0.1 0.8 26.2 2.1 0.3 20.2 6.9 1.7 0.2 5.6 0.3 98.4 6.1 0.8 32.3 62.1 0.5 41.7 403.3 341.0 71.9 441.4 66.1 41.5 53.1 60.2 309.6 21.8 45.6 48.2 498.1 61.9 454.6 125.2 56.4 380.7 10.8 13.1 13.6 14.4 11.2 16.6 22.2 14.3 19.1 15.4 17.8 24.6 2.2 3.2 20.0 0.3 42.6 3.2 1.1 2.7 0.6 0.4 1.0 0.6 0.7 2.8 8.7 0.0 0.0 0.8 87.5 0.3 0.0 0.9 2.3 4.5 1.8 6.8 10.7 6.1 6.2 8.3 1.3 1.8 1.1 6.4 13.3 7.1 3.6 1.3 62.6 0.0 0.7 0.2 36.7 135.9 59.9 5.2 0.6 125.4 17.8 6.5 144.8 0.1 54.6 0.5 14.7 8.7 0.0 0.4 57.3 3.0 0.0 0.4 3.2 0.2 0.0 21.9 2.1 1.8 2.9 0.1 1.1 2.5 21.2 3.0 0.8 5.0 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 141.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 10.4;Basal squamous epithelial cells: 8.0;Erythroid cells: 5.9;Gastric mucus-secreting cells: 11.2;Macrophages: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 438.1;intermediate monocyte: 420.9" "Group enriched" "Detected in all" 12 "dendritic cells: 283.5;granulocytes: 158.9;monocytes: 438.1" "Cell line enhanced" "Detected in many" "EFO-21: 43.6;RPMI-8226: 39.9;RPTEC TERT1: 110.6;U-937: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" NA NA 6770000 35000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" 27.7 31.6 39.5 37.7 43.7 48.4 29.5 39.7 47.3 33.5 66.7 45.9 74.7 13.3 19.2 12.5 31.8 54.1 18.0 35.3 37.6 55.6 16.2 100.7 33.1 44.8 43.3 24.8 41.1 18.0 19.7 14.7 41.1 22.6 41.9 13.0 141.9 32.1 5.3 10.5 39.5 24.8 40.0 30.6 54.0 4.6 44.8 14.1 27.0 10.1 24.5 26.0 15.5 38.8 20.8 8.3 2.8 5.5 3.2 1.7 3.4 3.7 2.7 1.5 1.3 4.6 12.8 9.1 43.6 3.8 5.2 13.1 0.1 3.6 1.6 16.2 7.0 5.9 18.2 9.7 6.7 5.1 5.9 3.6 3.6 1.0 5.7 8.8 4.7 6.5 4.6 3.5 1.3 3.1 2.3 16.6 2.7 20.3 6.0 16.5 3.4 39.9 110.6 13.5 5.1 4.9 7.2 18.8 2.5 4.1 25.2 12.4 2.4 4.8 5.8 2.1 8.1 0.8 2.8 2.4 1.9 44.1 9.5 75.2 438.1 158.9 0.9 420.9 0.8 13.7 0.5 0.7 283.5 25.0 2.4 1.5 56.9 7.9 265.4 130.8 0.9 257.1 39.5 43.7 39.7 47.3 35.3 37.6 44.8 43.3 41.1 40.0 44.8 38.8 0.2 6.4 10.4 0.0 2.1 0.0 0.2 0.2 8.0 0.1 0.4 0.1 0.0 0.0 2.0 1.8 0.0 0.0 0.1 1.0 0.0 0.4 0.0 0.2 0.1 0.0 1.2 5.9 0.0 0.2 0.0 2.9 11.2 0.4 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.0 19.5 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.2 0.7 0.3 1.5 0.2 0.0 0.1 0.2 0.0 0.0 2.6 0.0 0.0 0.8 0.1 0.6 0.2 TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.8;lung: 30.1" "Cell type enriched" "Detected in many" 8 "Hofbauer cells: 1014.1" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Group enriched" "Detected in some" 4 "hTCEpi: 74.6;THP-1: 42.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved "Secreted in brain" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" 10.7 13.2 28.1 3.5 31.1 0.2 9.8 33.7 61.5 6.5 29.1 3.5 0.9 1.6 2.3 0.6 7.4 9.7 2.1 27.5 32.3 1.3 2.3 30.1 2.6 44.5 34.4 2.4 3.9 7.4 3.9 10.7 42.7 2.0 4.3 1.9 6.0 3.1 0.4 0.5 1.4 4.5 46.7 0.5 2.5 0.7 43.5 1.8 1.7 0.0 0.4 4.5 0.6 69.8 0.0 0.3 0.0 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 1.2 74.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 42.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 28.1 31.1 33.7 61.5 27.5 32.3 44.5 34.4 42.7 46.7 43.5 69.8 1.8 6.4 7.5 0.0 0.7 0.8 0.2 79.8 0.0 0.3 1.8 58.8 0.1 1.5 9.6 0.0 0.0 5.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 10.4 0.0 0.0 0.0 0.0 4.9 1.2 0.0 0.0 2.5 0.0 2.2 0.2 1014.1 0.0 0.0 0.0 2.0 34.7 5.2 1.0 0.6 120.5 0.0 12.2 8.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 3.3 1.0 6.6 0.1 1.0 0.0 0.0 0.0 0.1 7.3 0.8 0.0 0.0 0.1 TRIM14 KIAA0129 ENSG00000106785 "Tripartite motif containing 14" Q14142 9 98069275-98119222 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 75.0;Kupffer cells: 80.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053217 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" "HPA053217: AB_2682082" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-1)" "unprognostic (9.80e-2)" "unprognostic (9.00e-2)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.55e-3)" "unprognostic (4.57e-2)" 6.4 5.3 9.0 18.4 7.6 12.1 10.0 4.7 7.7 5.8 4.7 18.9 29.5 4.3 1.8 19.5 6.3 9.6 1.6 7.7 7.3 11.4 22.3 14.9 25.6 14.1 8.1 2.9 3.1 13.5 5.1 5.0 8.4 9.4 16.8 2.7 10.6 5.6 1.0 9.9 30.4 8.8 9.4 26.8 11.6 7.8 9.7 32.7 2.9 1.0 21.8 12.7 9.1 8.9 25.5 12.9 0.6 11.3 0.0 3.9 8.3 14.8 28.1 79.3 67.8 24.8 14.9 33.5 11.8 16.1 47.2 28.6 24.9 16.5 24.1 43.3 20.0 9.9 20.3 24.6 17.1 53.1 10.7 2.4 8.0 11.6 14.8 10.6 10.1 37.4 39.6 15.5 7.3 32.6 42.2 16.7 14.2 56.3 39.5 27.4 1.4 17.2 6.3 15.6 4.0 3.3 20.8 43.2 14.3 2.8 11.4 30.4 7.1 3.3 8.5 1.2 20.5 6.7 8.3 11.1 9.1 41.1 11.4 1.0 14.4 2.1 15.1 28.4 16.1 8.3 17.1 15.7 15.8 5.6 13.1 11.4 4.0 13.0 59.0 15.3 23.1 17.2 9.0 7.6 4.7 7.7 7.7 7.3 14.1 8.1 8.4 9.4 9.7 8.9 2.1 3.2 8.8 3.3 15.3 2.8 14.3 11.8 15.4 35.1 8.7 8.3 1.0 7.2 14.2 5.5 75.0 5.0 28.8 40.0 3.9 4.9 8.8 4.8 8.9 4.1 12.6 5.9 7.0 13.6 16.9 3.2 13.3 5.4 1.3 12.0 7.5 22.4 15.4 3.3 5.4 15.3 10.2 80.6 2.4 9.9 0.3 32.6 1.8 2.8 16.5 1.9 30.9 12.1 0.9 15.0 13.5 1.5 8.5 19.1 38.1 21.1 17.0 4.4 0.0 1.4 2.0 16.3 3.8 17.3 3.3 3.3 21.3 5.8 19.4 21.1 TRPM2 "EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7" ENSG00000142185 "Transient receptor potential cation channel subfamily M member 2" O94759 21 44350163-44443081 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Sodium transport, Transport" "Calcium channel, Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.2;brain: 26.4;lymphoid tissue: 18.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.7;Hofbauer cells: 18.3;Inhibitory neurons: 45.1;Macrophages: 16.7;Microglial cells: 27.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 7.8;plasmacytoid DC: 15.5" "Group enriched" "Detected in many" 6 "dendritic cells: 15.5;monocytes: 7.8" "Cell line enhanced" "Detected in many" "HL-60: 41.7;NB-4: 58.6;OE19: 41.3;THP-1: 71.3;U-266/84: 31.8;U-937: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035260 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035260: AB_2674540" "unprognostic (3.61e-2)" "unprognostic (2.18e-1)" "unprognostic (7.55e-2)" "prognostic favorable (9.28e-4)" "unprognostic (6.49e-2)" "unprognostic (4.54e-2)" "unprognostic (5.17e-2)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (2.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.40e-1)" "unprognostic (3.31e-2)" "unprognostic (8.88e-3)" "prognostic favorable (7.59e-4)" 4.8 4.1 14.0 6.7 14.5 28.2 3.0 11.1 26.4 2.1 7.7 3.8 3.6 1.6 0.7 1.6 2.1 4.7 1.8 13.9 11.8 2.5 2.3 5.0 8.0 20.9 14.5 0.9 1.8 1.1 4.8 6.0 20.8 2.7 2.3 0.9 2.3 0.8 0.9 2.3 6.9 2.5 12.2 18.4 2.5 2.7 16.0 3.3 1.8 0.4 4.1 3.5 1.6 17.4 20.8 7.5 0.0 0.1 0.0 0.0 20.9 0.0 0.0 0.6 0.4 0.0 0.0 0.5 24.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.9 0.0 0.0 41.7 2.2 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 0.0 6.7 58.6 0.0 41.3 23.5 2.3 7.2 8.0 0.0 0.0 14.4 0.1 0.0 23.5 0.1 0.0 27.7 71.3 0.0 1.2 20.9 0.1 0.7 0.3 31.8 0.1 0.0 67.7 0.0 0.0 7.8 0.0 1.0 2.7 0.5 0.3 0.3 0.4 2.6 1.9 0.3 0.4 0.4 0.5 2.5 15.5 1.3 2.0 14.0 14.5 11.1 26.4 13.9 11.8 20.9 14.5 20.8 12.2 16.0 17.4 2.0 0.0 0.5 1.3 2.0 0.4 0.0 0.0 0.6 1.4 2.8 3.0 1.7 0.0 0.0 0.0 0.0 1.8 9.9 0.8 0.0 0.1 2.1 0.7 0.2 2.7 0.0 0.0 52.7 0.2 8.8 0.5 1.1 1.2 1.3 0.3 0.4 0.4 18.3 0.0 45.1 1.0 0.0 11.0 5.5 2.0 0.6 16.7 0.0 27.2 5.5 0.5 6.2 4.0 1.7 1.2 0.1 0.0 1.4 0.0 0.0 0.3 0.0 1.0 6.6 0.5 0.4 1.0 0.1 0.1 0.3 1.4 4.2 0.0 0.7 0.0 UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 76.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 96.2;Kupffer cells: 78.3;Macrophages: 85.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "CAPAN-2: 128.9;RPMI-8226: 368.2;SK-BR-3: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA038716: AB_2676169, HPA038717: AB_10674836, HPA042803: AB_2678176" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.32e-2)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (7.66e-2)" "unprognostic (1.29e-2)" "unprognostic (9.36e-2)" "unprognostic (5.82e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (4.76e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.73e-2)" "unprognostic (1.85e-2)" "unprognostic (7.05e-3)" "unprognostic (5.23e-3)" 18.7 17.7 4.9 19.9 5.6 19.9 15.4 5.0 7.5 19.0 6.4 20.2 22.5 7.7 0.8 20.5 15.7 9.8 7.3 4.9 5.0 16.4 15.3 29.5 29.5 10.7 6.5 6.2 17.1 2.6 6.7 6.4 8.1 16.4 3.1 0.1 27.9 8.8 3.5 16.3 35.8 3.1 7.9 76.7 20.6 1.7 6.8 3.5 14.8 1.5 7.3 20.6 15.0 10.2 18.9 34.1 2.5 13.8 7.2 2.7 28.2 8.3 7.7 13.0 11.8 2.8 128.9 40.9 30.8 4.0 11.0 44.9 1.0 7.0 0.4 14.1 9.3 4.2 11.1 6.4 11.2 30.0 22.7 6.0 7.6 3.8 1.5 5.0 2.6 6.4 3.0 19.3 2.0 18.7 0.2 23.9 6.2 46.8 16.7 24.5 0.0 368.2 11.8 10.7 3.9 5.5 14.0 95.6 19.3 1.0 35.4 39.0 9.2 8.6 12.2 12.8 0.8 13.2 18.8 7.0 16.0 30.7 10.5 0.1 3.8 6.6 0.1 7.2 0.2 2.5 0.2 0.2 5.1 2.7 0.0 0.0 3.2 2.1 7.7 14.8 0.0 1.2 4.9 5.6 5.0 7.5 4.9 5.0 10.7 6.5 8.1 7.9 6.8 10.2 12.5 9.6 9.1 4.6 45.3 4.0 21.9 12.5 9.1 0.0 16.4 13.1 1.8 40.0 21.0 16.5 0.0 10.3 63.3 23.2 1.9 36.8 0.8 32.0 5.9 10.0 4.2 3.0 1.1 23.4 47.8 8.0 20.9 17.2 7.0 9.3 10.0 5.4 96.2 5.0 0.1 17.2 14.2 78.3 28.4 0.1 4.4 85.3 23.2 13.1 57.5 4.7 8.2 0.0 0.7 49.7 25.6 4.1 33.8 27.0 31.7 6.9 57.3 0.5 0.0 8.3 9.8 0.2 1.1 12.9 6.5 7.3 10.5 2.1 23.1 37.7 VAV1 VAV ENSG00000141968 "Vav guanine nucleotide exchange factor 1" P15498 19 6772708-6857366 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.1;lymphoid tissue: 46.4" "Cell type enhanced" "Detected in many" "B-cells: 30.7;dendritic cells: 31.3;granulocytes: 34.9;Hofbauer cells: 50.6;Kupffer cells: 29.4;Macrophages: 33.9;Microglial cells: 30.9;T-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 100.7;Karpas-707: 114.7;MOLT-4: 115.8;REH: 76.1;THP-1: 88.9;U-266/84: 89.5;U-937: 95.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001864, HPA005925" Enhanced Approved Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA001864: AB_1858722, HPA005925: " "unprognostic (2.93e-1)" "unprognostic (1.96e-1)" "unprognostic (1.80e-1)" "unprognostic (1.01e-1)" "unprognostic (6.82e-2)" "unprognostic (1.13e-2)" "unprognostic (5.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-2)" "unprognostic (3.56e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (9.55e-2)" "unprognostic (1.78e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" 6.6 3.8 3.3 36.3 3.3 54.1 2.7 3.6 4.6 2.6 4.5 6.5 5.8 1.8 1.4 3.7 2.4 6.3 1.9 3.3 4.4 2.1 5.0 11.5 46.4 6.2 4.9 1.1 1.3 4.2 1.6 8.7 5.6 2.8 7.1 0.2 6.1 2.3 1.0 1.7 14.1 5.3 5.0 44.9 5.5 1.8 5.7 45.7 2.0 2.1 39.1 13.0 1.7 7.6 1.6 2.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 12.7 51.0 16.5 0.0 0.0 0.2 0.0 0.0 0.0 22.0 1.8 61.8 0.0 0.0 0.0 60.7 100.7 0.0 0.0 0.0 0.0 0.0 0.0 63.9 2.3 114.7 0.0 9.6 115.8 36.6 0.0 0.0 0.0 76.1 0.0 41.0 2.2 0.0 0.0 0.0 0.0 18.3 0.1 0.0 8.0 88.9 0.2 0.0 1.6 0.1 0.1 69.9 89.5 57.9 0.1 95.3 0.0 1.6 18.3 20.0 22.0 30.3 15.7 14.3 16.1 19.3 16.6 13.6 17.2 15.6 40.6 19.2 39.8 14.4 14.5 18.2 3.3 3.3 3.6 4.6 3.3 4.4 6.2 4.9 5.6 5.0 5.7 7.6 0.5 3.2 3.0 0.0 30.7 1.3 0.8 3.7 0.0 0.5 0.4 0.4 1.1 0.0 6.9 0.0 0.0 0.8 31.3 1.5 0.0 4.2 5.4 5.3 0.3 1.5 1.2 9.9 1.9 0.4 0.7 1.2 1.1 1.1 34.9 0.0 1.8 0.3 50.6 0.0 1.5 1.0 8.2 29.4 19.6 2.2 0.0 33.9 1.8 30.9 18.8 0.0 22.6 0.5 1.2 9.9 6.1 0.0 21.6 0.3 0.0 0.2 11.9 0.0 0.0 0.3 1.2 1.7 1.4 0.3 0.9 1.4 26.5 0.3 2.4 0.6 VENTX "HPX42B, VENTX2" ENSG00000151650 "VENT homeobox" O95231 10 133237855-133241928 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Kupffer cells: 6.2;Langerhans cells: 7.9;Macrophages: 7.8;monocytes: 5.0" "Cancer enriched" "Detected in some" 15 "testis cancer: 30.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;granulocytes: 1.9;monocytes: 3.2" "Group enriched" "Detected in some" 10 "NB-4: 18.2;NTERA-2: 10.9" HPA050955 Uncertain Uncertain "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center" Cytosol "HPA050955: AB_2681288" "unprognostic (9.41e-2)" "unprognostic (8.89e-2)" "unprognostic (2.34e-1)" "unprognostic (4.26e-1)" "unprognostic (3.22e-2)" "unprognostic (2.01e-1)" "unprognostic (2.54e-1)" "unprognostic (9.62e-3)" "unprognostic (2.22e-1)" "unprognostic (3.00e-3)" "unprognostic (3.70e-4)" "unprognostic (4.22e-1)" "unprognostic (2.51e-3)" "unprognostic (3.43e-2)" "unprognostic (3.48e-1)" "unprognostic (7.54e-2)" "unprognostic (3.14e-1)" 4.8 2.3 1.6 3.6 1.1 2.8 1.9 1.6 1.5 1.5 1.9 1.9 0.4 1.6 0.5 0.5 1.8 1.5 1.5 1.5 1.5 1.7 0.5 3.8 0.5 1.9 1.7 1.5 1.2 0.5 1.4 0.5 1.5 1.3 0.4 0.2 1.3 0.8 0.9 1.2 1.0 1.2 0.9 5.7 0.9 1.0 2.5 0.2 0.8 0.1 0.4 1.4 1.0 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 18.2 10.9 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 1.9 2.6 0.3 0.1 3.2 0.0 0.3 0.1 0.0 1.8 0.2 0.1 0.1 0.9 0.3 2.4 0.1 0.0 0.7 1.6 1.1 1.6 1.5 1.5 1.5 1.9 1.7 1.5 0.9 2.5 1.8 0.0 0.0 1.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 7.9 0.2 0.0 7.8 0.0 0.0 5.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WDFY4 "C10orf64, Em:AC060234.3, FLJ45748, KIAA1607" ENSG00000128815 "WDFY family member 4" Q6ZS81 10 48684876-48982956 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.7;lymphoid tissue: 28.5" "Cell type enhanced" "Detected in some" "B-cells: 44.7;dendritic cells: 29.9;Early spermatids: 47.2;Langerhans cells: 30.6;Macrophages: 24.6;Microglial cells: 81.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 14.3;myeloid DC: 11.3;naive B-cell: 21.2;neutrophil: 10.2;plasmacytoid DC: 32.5" "Group enriched" "Detected in many" 7 "B-cells: 21.2;dendritic cells: 32.5;granulocytes: 10.2" "Cell line enhanced" "Detected in some" "Daudi: 61.0;HDLM-2: 56.3;HL-60: 21.5;THP-1: 18.9;U-698: 25.6;U-937: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA040634 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA040634: AB_10795491" "unprognostic (6.20e-2)" "unprognostic (6.60e-3)" "unprognostic (1.87e-1)" "unprognostic (3.31e-2)" "unprognostic (1.87e-1)" "unprognostic (9.38e-4)" "unprognostic (9.41e-2)" "unprognostic (3.89e-3)" "unprognostic (2.15e-2)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" "unprognostic (9.64e-2)" "unprognostic (3.21e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.76e-2)" 1.9 0.7 3.2 12.1 3.4 11.7 1.4 4.2 4.8 1.1 3.2 1.9 1.5 0.8 1.9 1.4 0.7 3.2 0.6 3.2 4.2 0.8 1.3 5.2 28.5 6.0 4.9 0.6 1.0 0.4 0.3 1.2 6.2 0.8 1.9 0.1 1.3 0.6 0.7 2.6 7.4 1.7 5.9 17.3 2.3 3.7 6.3 12.3 0.6 0.4 23.9 3.1 0.3 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 6.5 0.0 0.0 0.0 21.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 25.0 0.0 0.0 3.0 0.0 0.0 2.8 0.0 14.3 0.0 0.1 11.3 21.2 0.0 0.0 10.2 0.0 1.3 32.5 0.0 1.1 3.2 3.4 4.2 4.8 3.2 4.2 6.0 4.9 6.2 5.9 6.3 9.3 0.2 0.0 1.1 2.0 44.7 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.3 0.0 0.6 1.8 0.0 0.1 29.9 0.0 1.9 0.0 47.2 0.0 0.1 0.3 0.0 0.4 0.7 0.0 0.2 1.1 0.0 0.0 5.7 0.0 0.0 0.0 13.0 0.0 0.4 0.1 0.0 12.9 30.6 17.7 0.3 24.6 1.8 81.5 16.4 0.0 0.0 1.0 0.5 0.0 0.0 0.4 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 2.9 0.5 0.2 0.3 0.3 1.5 0.0 0.3 0.1 ZC3H12D "C6orf95, dJ281H8.1, MCPIP4" ENSG00000178199 "Zinc finger CCCH-type containing 12D" A2A288 6 149446795-149485014 "Disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.6;intestine: 4.7;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "B-cells: 14.6;Distal enterocytes: 7.7;Kupffer cells: 12.4;Macrophages: 7.4;Proximal enterocytes: 7.5;T-cells: 17.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HDLM-2: 34.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036897 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytoplasmic bodies" "HPA036897: AB_10672104" "unprognostic (2.89e-2)" "unprognostic (3.91e-4)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.47e-6)" "unprognostic (2.20e-2)" "unprognostic (2.50e-3)" "unprognostic (1.34e-1)" "unprognostic (3.30e-2)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.28e-4)" "unprognostic (1.21e-2)" "unprognostic (9.24e-3)" "unprognostic (6.99e-2)" "unprognostic (5.52e-2)" 0.7 0.4 1.0 7.2 0.5 3.6 0.4 0.4 0.9 0.3 0.3 1.5 2.8 0.2 0.2 0.3 0.3 0.6 0.3 0.8 0.9 0.6 0.3 0.8 9.8 1.0 0.5 0.3 0.1 0.0 0.2 0.3 0.8 0.3 1.4 0.5 0.7 0.3 0.4 1.1 4.7 0.5 0.4 5.8 0.8 0.3 0.9 1.1 0.5 0.0 12.6 1.0 0.2 0.9 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.1 8.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 34.3 0.2 0.3 1.2 2.7 0.0 2.8 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.7 0.0 0.1 0.0 2.5 0.0 0.0 0.0 7.1 0.0 0.9 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 4.6 0.0 0.2 0.1 0.1 0.1 0.1 0.2 2.9 0.4 2.5 0.1 0.7 0.8 0.1 0.1 0.5 0.2 1.4 1.5 0.7 0.8 1.3 0.9 0.2 0.5 0.3 1.4 0.4 3.5 0.8 1.0 0.5 0.4 0.9 0.8 0.9 1.0 0.5 0.8 0.4 0.9 0.9 1.0 3.2 3.9 1.3 14.6 0.4 0.5 0.0 0.0 0.7 0.3 0.3 1.4 1.5 0.6 0.0 4.2 0.0 3.7 7.7 1.9 0.0 0.4 0.4 0.4 1.3 0.0 0.4 1.2 0.4 0.0 0.7 0.5 0.6 0.0 0.2 1.4 0.3 3.7 0.0 0.7 1.1 0.0 12.4 4.4 0.5 0.0 7.4 1.8 1.0 1.6 0.8 0.0 0.0 0.7 0.3 0.8 0.0 4.6 0.4 7.5 1.6 0.0 1.1 0.0 0.9 0.4 0.2 0.4 0.1 1.4 0.0 17.4 0.0 2.6 0.4