Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 675.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 567.6;Proximal tubular cells: 272.5" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038097 Approved "Secreted to blood" NA NA 225000000 120000000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 53.0 675.7 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 4.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 11.5 0.0 5.5 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.1 0.1 0.7 0.0 16.0 0.1 0.2 0.1 0.0 2.6 0.3 0.0 0.0 9.7 567.6 0.1 0.0 0.1 0.0 0.0 16.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 81.5" "Cell type enhanced" "Detected in some" "Late spermatids: 12.5;Muller glia cells: 9.0;Proximal enterocytes: 17.1;Sertoli cells: 6.6" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" NA NA 2200000 "Cluster 32: T-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" 0.4 0.8 0.0 0.2 1.1 0.0 0.5 8.1 0.4 0.7 0.1 0.8 81.5 0.8 0.5 0.7 0.8 0.3 0.8 0.1 0.4 0.5 2.9 0.6 0.3 3.2 2.9 0.8 1.4 0.6 0.6 0.6 2.2 0.4 0.4 7.3 0.6 0.2 0.8 0.7 64.6 1.2 1.5 0.2 5.0 0.8 0.6 0.5 0.7 0.4 0.1 0.5 0.4 0.6 1.2 0.9 1.0 1.4 1.8 0.7 1.3 1.2 0.9 2.5 2.2 0.7 3.0 0.0 1.4 1.9 2.0 1.1 1.4 0.4 3.0 1.6 2.5 0.9 2.2 1.9 1.1 0.3 0.1 0.2 1.7 4.3 4.8 0.3 0.5 0.0 1.7 0.8 1.7 1.1 1.0 0.0 3.2 0.0 2.7 0.0 4.2 1.1 1.3 0.2 1.8 4.8 1.7 1.2 2.1 2.4 1.0 0.7 1.4 1.2 2.8 3.2 4.0 1.2 0.1 0.0 3.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.1 8.1 0.4 0.1 0.4 3.2 2.9 2.2 1.5 0.6 0.6 0.1 0.0 0.0 0.7 0.0 0.4 0.3 0.4 0.0 2.8 0.4 0.3 3.8 0.0 0.9 0.0 2.1 0.4 1.4 0.5 0.0 0.9 4.8 0.1 0.2 0.5 0.0 3.2 1.1 1.6 0.3 0.6 0.0 0.2 0.0 0.2 0.4 2.1 0.2 1.7 1.5 1.8 0.0 0.0 0.0 12.5 1.2 0.0 0.0 0.0 0.0 9.0 1.0 0.0 0.2 1.6 0.1 1.5 0.0 0.3 17.1 1.0 0.7 2.1 6.6 0.6 0.9 1.9 0.9 0.0 0.1 0.3 0.5 0.2 1.2 0.2 ATP4A ATP6A ENSG00000105675 "ATPase H+/K+ transporting subunit alpha" P20648 19 35550031-35563658 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "stomach 1: 841.9" "Group enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 66.3;Late spermatids: 21.0" "Cancer enriched" "Detected in single" 21 "stomach cancer: 5.4" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039154, HPA076684" Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039154: AB_10672772, HPA076684: " "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.77e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-1)" "unprognostic (9.68e-2)" "unprognostic (1.47e-3)" "unprognostic (3.90e-3)" "unprognostic (3.92e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" 1.1 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.0 10.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 841.9 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 66.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.0 0.6 1.2 0.0 0.0 0.6 0.1 0.0 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1859 "stomach 1: 1575.7" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" NA NA "Cluster 4: Stomach - Digestion" "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.6 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1575.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CKMT2 SMTCK ENSG00000131730 "Creatine kinase, mitochondrial 2" P17540 5 81233320-81266398 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 49 "heart muscle: 1240.1;skeletal muscle: 1430.8;tongue: 2324.4" "Cell type enriched" "Detected in many" 20 "Cardiomyocytes: 814.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Cell line enhanced" "Detected in many" "BEWO: 3.5;T-47d: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051880 Enhanced NA NA 3000000 "Cluster 48: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA051880: AB_2681650" "unprognostic (3.64e-3)" "unprognostic (1.15e-1)" "unprognostic (2.82e-3)" "unprognostic (1.88e-2)" "unprognostic (1.21e-2)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (3.57e-2)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.75e-3)" 18.2 33.6 12.3 0.8 15.0 0.1 4.6 17.3 12.3 8.1 24.4 3.2 1.1 6.4 11.4 20.2 6.9 8.1 1240.1 11.2 15.0 14.7 1.0 2.5 1.3 16.3 16.8 10.2 7.7 15.7 4.5 0.7 14.9 13.1 0.7 1.6 26.3 13.1 1430.8 4.7 2.8 8.8 12.0 1.8 17.9 3.6 16.1 0.8 4.9 2324.4 0.4 4.1 4.1 17.7 0.3 0.7 0.8 1.3 1.9 0.4 3.5 0.1 0.0 0.0 0.0 2.4 0.2 1.4 0.4 0.0 1.0 0.0 0.0 0.0 0.0 1.5 2.4 0.1 1.0 3.2 2.6 0.6 0.2 0.8 0.0 0.0 0.0 0.3 0.0 2.1 0.3 0.5 0.0 2.2 1.2 0.2 1.0 0.0 0.7 0.6 1.0 0.1 0.0 0.0 1.4 1.0 1.2 0.3 1.4 1.5 6.3 0.3 0.7 0.4 1.2 0.7 0.2 0.2 0.1 1.3 0.4 0.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 12.3 15.0 17.3 12.3 11.2 15.0 16.3 16.8 14.9 12.0 16.1 17.7 1.8 0.0 0.5 40.1 0.0 0.1 0.4 0.0 1.2 0.9 0.9 0.8 814.1 7.2 0.6 12.9 0.0 0.1 0.0 0.1 37.2 1.7 25.1 13.6 3.5 9.8 0.0 0.0 11.4 0.6 0.4 16.2 6.6 27.8 0.0 0.8 0.0 0.0 0.1 0.0 18.1 0.3 0.0 0.0 0.0 2.2 7.2 0.3 3.6 23.4 0.0 1.4 0.0 4.5 9.1 0.4 0.0 15.1 0.0 0.3 0.3 0.6 0.7 1.0 0.0 11.6 15.0 1.0 0.4 0.1 0.1 0.3 0.8 23.7 2.5 0.2 CLCNKA hClC-Ka ENSG00000186510 "Chloride voltage-gated channel Ka" P51800 1 16018875-16034050 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Bartter syndrome, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 344.0" "Cell type enriched" "Detected in some" 4 "Late spermatids: 271.5" "Group enriched" "Detected in some" 7 "renal cancer: 4.4;thyroid cancer: 1.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/70: 7.4" HPA057717 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA057717: AB_2683509" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (4.02e-1)" "unprognostic (2.76e-3)" "unprognostic (8.20e-2)" "unprognostic (6.16e-2)" "unprognostic (1.18e-2)" "unprognostic (6.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (8.13e-3)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (4.37e-3)" "unprognostic (1.28e-1)" 0.7 2.9 0.4 0.0 0.4 0.0 0.9 2.2 0.4 0.6 4.9 0.4 0.0 0.6 0.5 0.0 0.5 0.1 0.6 0.7 0.4 344.0 0.2 0.3 0.0 0.4 0.5 0.9 3.5 48.9 18.2 0.0 0.7 0.8 0.0 2.3 6.9 0.2 0.5 0.7 0.1 0.2 0.3 0.1 3.9 4.5 0.4 0.0 21.6 0.3 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 2.2 0.4 0.7 0.4 0.4 0.5 0.7 0.3 0.4 0.4 0.0 3.2 0.5 0.3 0.0 0.1 0.1 0.0 0.0 3.9 0.4 0.1 3.8 0.0 0.7 25.8 0.0 0.4 0.0 0.1 25.4 0.3 40.2 0.1 0.0 0.1 1.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 4.5 0.0 0.0 0.1 13.5 0.2 0.1 67.1 0.0 0.0 271.5 0.3 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.1 1.9 1.2 0.0 0.0 0.7 0.1 0.0 0.3 0.2 CLIC6 "CLIC1L, CLIC5" ENSG00000159212 "Chloride intracellular channel 6" Q96NY7 21 34668994-34718227 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 235.9;stomach 1: 138.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Club cells: 41.6;Gastric mucus-secreting cells: 26.5;Respiratory ciliated cells: 81.1;Skeletal myocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.6;NTERA-2: 3.6;T-47d: 7.3;THP-1: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065285 Enhanced NA NA 180000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA065285: AB_2685454" "prognostic favorable (6.11e-5)" "unprognostic (2.17e-2)" "unprognostic (1.65e-2)" "unprognostic (4.27e-2)" "unprognostic (2.93e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-2)" "prognostic favorable (3.15e-5)" "unprognostic (4.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.99e-1)" "unprognostic (1.43e-3)" 11.4 0.1 1.2 4.3 0.7 0.1 11.9 2.4 1.0 15.8 235.9 4.0 2.0 2.1 2.7 2.6 11.4 8.8 11.1 11.3 0.7 2.6 0.9 9.8 1.2 3.0 4.5 4.9 3.2 28.3 3.3 0.1 2.6 9.8 2.9 0.2 25.4 7.0 1.6 6.0 3.1 0.7 1.3 1.0 138.5 0.3 4.4 8.4 13.2 4.3 3.8 12.9 5.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.9 7.3 3.4 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 2.4 1.0 11.3 0.7 3.0 4.5 2.6 1.3 4.4 0.7 0.3 6.4 20.7 1.3 0.0 0.6 5.1 7.3 4.0 0.0 15.6 11.0 11.4 30.0 41.6 9.2 0.0 0.0 0.2 2.2 1.9 8.0 0.1 15.1 0.3 0.4 4.9 0.0 0.3 0.9 0.0 3.7 26.5 2.2 1.3 11.8 0.0 0.0 0.1 0.0 0.6 1.4 16.2 0.0 0.4 0.3 0.3 0.4 7.2 0.0 0.6 0.0 0.0 0.0 0.1 17.2 0.6 3.0 0.4 10.2 0.1 0.2 81.1 0.0 0.0 24.0 2.4 0.2 0.2 0.6 0.4 0.0 0.4 0.0 2.8 20.4 CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 416 "pancreas: 45360.2" "Cell type enriched" "Detected in some" 10 "Exocrine glandular cells: 4973.8" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.2;CACO-2: 3.8;RH-30: 3.0;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" NA NA 1500000 "Cluster 25: Pancreas - Digestion" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" 5.5 1.0 0.3 0.7 0.8 0.4 2.6 1.0 0.9 1.9 0.2 1.3 17.4 0.8 0.1 1.5 0.7 0.0 8.4 0.3 0.6 0.9 2.6 0.7 1.4 2.8 1.3 19.7 45360.2 0.0 1.4 3.2 2.5 1.5 0.4 0.8 7.8 0.0 0.8 1.1 30.6 0.0 1.2 1.2 108.9 2.2 1.1 0.1 0.6 0.0 0.0 0.5 0.8 3.1 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.8 0.0 0.0 0.5 0.0 0.3 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 3.0 0.0 0.0 0.3 1.6 0.0 0.1 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.6 0.4 0.3 0.0 0.4 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.0 0.9 0.3 0.6 2.8 1.3 2.5 1.2 1.1 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.6 1.9 8.1 4.3 0.0 0.0 0.9 0.0 0.0 0.1 4973.8 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 10.5 0.3 0.5 0.0 0.0 13.9 4.6 0.0 0.5 1.0 471.3 52.9 0.0 0.0 0.0 9.9 0.0 0.0 0.3 0.0 0.0 1.3 0.4 2.0 0.0 0.1 0.3 0.0 0.2 1.5 0.2 ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 36.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 13.7;Early spermatids: 14.1;Horizontal cells: 55.5;Late spermatids: 37.6;Rod photoreceptor cells: 40.3" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.3;K-562: 5.0;U-266/70: 2.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA074772: " "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.92e-5)" "unprognostic (5.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.14e-1)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.24e-2)" "unprognostic (2.16e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-1)" "unprognostic (3.46e-1)" "unprognostic (1.89e-1)" "unprognostic (2.12e-4)" "unprognostic (4.40e-2)" 0.0 0.0 0.4 0.0 0.4 0.0 0.3 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.9 0.3 0.6 6.6 0.0 0.0 0.0 1.5 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 36.5 0.0 0.0 6.5 0.0 0.0 0.0 0.6 0.1 2.4 1.2 0.9 0.1 0.0 1.6 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.2 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.2 2.3 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 0.4 0.3 0.6 1.5 1.2 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.4 1.0 0.4 5.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 13.7 0.0 14.1 0.0 0.0 0.8 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.5 2.0 0.0 0.0 0.0 0.0 37.6 0.0 0.1 0.0 3.7 0.0 4.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 40.3 0.0 0.1 0.8 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053166-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;lymphoid tissue: 13.1;stomach 1: 5.7;testis: 5.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 68.9;Paneth cells: 167.2" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 1.9;RPMI-8226: 3.0" "Low region specificity" "Detected in many" HPA030347 Enhanced Approved "Actin filaments" NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" 3.6 0.0 0.0 0.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 6.8 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.2 0.0 3.1 0.1 0.0 2.1 5.7 5.1 0.0 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 1.8 0.0 0.0 0.0 68.9 0.0 0.0 15.3 0.0 0.0 0.2 7.8 0.0 0.0 1.8 0.0 0.4 4.6 0.1 0.0 0.3 0.4 0.6 0.0 0.0 0.0 16.0 0.0 0.0 0.0 20.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 167.2 1.5 0.0 0.0 19.6 23.8 0.0 0.0 0.0 0.3 0.7 13.4 8.2 0.0 0.0 0.1 0.1 15.2 12.6 0.2 GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 16.4;Hofbauer cells: 21.3;Kupffer cells: 31.9;Macrophages: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 64.1;HMC-1: 57.1;HUVEC TERT2: 24.0;NB-4: 29.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" 9.9 10.5 6.3 11.0 5.9 9.9 6.5 11.8 7.0 5.4 11.8 5.3 3.3 6.7 2.7 3.6 7.4 7.5 6.7 5.9 8.2 5.6 1.3 9.7 9.7 13.5 11.2 12.5 3.4 4.8 4.2 12.8 13.8 6.1 3.2 1.0 4.8 4.2 2.2 3.5 6.7 6.7 7.7 8.9 22.2 1.3 11.5 2.7 6.7 2.9 8.1 6.0 6.3 8.5 0.1 1.6 1.5 0.0 1.0 1.1 0.5 4.7 3.8 2.6 0.1 0.0 0.9 1.2 15.5 4.7 1.7 17.3 10.5 1.0 0.1 0.0 0.5 64.1 1.1 0.0 12.4 2.4 57.1 5.3 1.7 0.6 0.1 10.5 24.0 0.8 18.7 0.2 1.0 0.3 0.2 29.0 4.9 0.5 0.4 4.5 0.4 1.7 1.6 0.2 0.4 1.8 0.0 2.6 0.1 2.0 0.1 14.0 14.8 0.0 2.0 1.9 0.1 0.0 0.0 0.1 0.3 10.2 0.8 6.2 10.7 5.2 0.2 7.2 0.4 1.8 0.3 0.0 3.0 2.7 0.1 0.1 1.7 0.2 6.4 2.2 0.2 2.5 6.3 5.9 11.8 7.0 5.9 8.2 13.5 11.2 13.8 7.7 11.5 8.5 1.6 0.0 1.7 4.9 4.9 0.8 2.2 0.6 2.8 0.3 4.1 2.7 2.6 1.5 0.7 1.8 0.0 2.4 0.0 0.6 0.0 3.2 0.0 0.5 1.8 1.8 0.0 16.4 2.4 0.6 1.1 7.3 2.6 0.3 11.4 3.6 0.7 0.0 21.3 0.0 1.9 0.3 0.0 31.9 3.1 0.0 7.5 22.0 0.0 5.6 11.1 2.4 0.0 1.5 0.0 0.8 12.1 1.9 0.7 1.5 0.1 1.6 0.0 0.2 0.0 3.9 6.2 0.1 0.1 1.4 1.1 3.6 2.0 0.5 1.2 1.7 GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.3;skeletal muscle: 35.8;tongue: 12.5" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 89.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.9;NTERA-2: 2.1;PC-3: 6.1;SCLC-21H: 3.4;U-2 OS: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035673: AB_10669776" "unprognostic (1.48e-1)" "unprognostic (6.26e-3)" "unprognostic (2.43e-2)" "unprognostic (3.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.14e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-2)" "unprognostic (9.14e-2)" "unprognostic (2.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (5.82e-1)" "unprognostic (4.01e-1)" 1.1 1.1 3.0 0.7 2.7 0.0 1.0 0.0 6.2 1.1 0.0 0.8 0.4 1.1 0.4 2.2 0.8 1.2 13.3 0.2 3.5 2.3 0.3 0.4 0.4 2.9 5.8 3.4 0.5 0.3 1.0 3.9 2.1 0.9 1.0 0.3 0.9 0.4 35.8 2.0 1.0 1.0 1.7 1.6 4.5 0.7 9.6 0.3 0.8 12.5 0.7 1.0 1.2 1.8 0.1 0.9 0.0 0.0 0.3 0.2 0.0 0.3 3.1 0.3 1.9 1.2 0.0 0.0 0.7 0.2 0.5 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 1.5 6.1 0.0 0.0 0.0 0.0 0.0 3.4 0.6 0.3 0.0 1.0 1.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 6.2 0.2 3.5 2.9 5.8 2.1 1.7 9.6 1.8 2.3 0.0 0.5 2.3 0.1 0.0 0.1 0.0 1.2 14.9 0.1 1.3 8.5 0.0 0.6 0.0 14.6 0.0 0.7 0.1 0.0 0.0 3.0 2.1 1.4 0.8 4.2 0.0 3.0 0.2 0.0 2.0 2.0 4.9 0.0 0.0 1.1 0.0 0.1 0.0 89.0 0.1 0.0 0.0 0.0 5.2 4.1 0.7 0.0 2.8 0.0 0.5 0.0 0.5 0.9 0.0 0.0 2.2 0.3 0.1 0.0 0.2 0.0 21.9 19.7 4.3 14.7 0.1 0.8 0.2 0.0 0.1 0.3 1.1 0.0 0.0 GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 143.1" "Cell type enriched" "Detected in some" 7 "Paneth cells: 18841.5" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 1.4;CACO-2: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Secreted to blood" NA NA 77700 1200000 "Cluster 7: Monocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 89.4 36.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 5.5 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 23.3 0.0 0.0 0.6 0.0 0.1 143.1 0.6 0.0 0.0 18.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 1098.8 0.0 0.9 1.0 0.0 0.0 0.0 22.8 0.0 0.0 47.9 0.3 0.0 0.0 0.0 22.3 0.0 0.4 3.1 0.1 0.0 0.0 107.2 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 18841.5 0.0 0.0 0.0 2568.9 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 1.3 0.0 55.3 0.9 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 66.7;stomach 1: 132.6" "Cell type enhanced" "Detected in some" "Adipocytes: 11.3;Collecting duct cells: 9.2;Distal tubular cells: 13.7;Endometrial ciliated cells: 9.9;Glandular and luminal cells: 40.5;Proximal tubular cells: 7.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 17 "amygdala: 11.4;basal ganglia: 8.4;cerebral cortex: 18.4;hippocampal formation: 14.1;white matter: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.8" HPA055407 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" 2.2 0.4 11.4 1.1 8.4 0.0 2.7 0.6 18.4 8.5 0.0 13.8 1.9 1.0 9.2 1.4 2.5 16.8 0.9 14.1 0.0 66.7 0.2 6.8 0.4 0.0 0.0 0.6 1.4 0.4 1.5 6.2 0.0 1.4 18.2 14.0 17.1 0.6 0.3 5.1 1.4 0.8 0.0 0.6 132.6 0.5 0.0 0.6 0.4 0.7 1.3 0.7 0.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 8.4 0.6 18.4 14.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 11.3 6.4 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.8 2.9 0.0 0.0 6.2 9.2 0.0 0.5 0.7 0.0 13.7 1.4 0.0 9.9 6.0 2.5 0.0 0.0 0.0 6.2 0.1 0.5 0.0 40.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 7.7 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.8 0.2 0.0 0.0 PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Distal tubular cells: 46.9;Early spermatids: 38.2;granulocytes: 67.2;Late spermatids: 123.0;Proximal tubular cells: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 38.1;CAPAN-2: 46.4;fHDF/TERT166: 33.1;HMC-1: 79.8;U-87 MG: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" 0.6 16.0 3.5 2.6 2.8 1.2 1.2 2.7 3.0 1.7 12.0 19.0 2.3 1.0 0.2 12.4 0.9 2.0 0.8 3.1 2.8 52.9 1.1 9.1 0.3 3.4 3.1 0.6 5.1 11.3 0.8 1.6 4.0 0.6 16.2 1.9 1.8 3.7 0.2 4.9 8.0 0.9 2.8 0.4 7.7 2.4 4.4 0.2 0.8 0.2 2.1 3.6 2.9 2.9 11.7 38.1 0.8 0.8 1.6 4.2 0.3 3.7 22.2 4.3 9.1 2.2 46.4 0.1 5.9 33.1 3.7 0.7 10.9 0.6 7.4 0.1 1.7 6.9 5.6 0.8 2.9 0.2 79.8 2.2 1.7 19.4 20.7 5.5 0.0 0.2 0.1 0.7 18.4 1.6 0.2 0.2 2.6 6.1 3.2 0.1 0.6 2.2 16.6 0.9 3.3 0.7 6.0 2.3 3.1 2.1 1.0 2.8 0.6 13.1 4.2 1.1 0.4 0.2 0.3 0.1 33.1 0.1 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 2.8 2.7 3.0 3.1 2.8 3.4 3.1 4.0 2.8 4.4 2.9 0.1 12.8 21.0 1.0 0.5 0.9 1.3 0.4 1.2 0.7 1.3 0.8 0.7 32.9 0.9 20.2 0.0 0.0 0.0 31.1 46.9 19.0 38.2 0.7 0.1 1.9 0.0 0.0 0.5 0.4 0.0 2.8 2.0 1.5 67.2 2.2 0.0 0.0 3.7 0.0 0.7 4.8 0.0 0.3 0.7 123.0 0.9 1.8 0.0 20.6 0.0 5.9 0.0 1.0 0.5 2.6 6.9 1.2 0.0 1.4 26.8 42.3 0.8 0.1 6.6 0.1 0.6 0.5 0.5 15.1 1.8 0.1 0.4 19.6 13.7 0.8 PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;granulocytes: 4.5;Oligodendrocyte precursor cells: 1.5;Proximal enterocytes: 1.5;Proximal tubular cells: 3.8;Suprabasal keratinocytes: 3.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "basophil: 69.8;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.8" "Cell line enriched" "Detected in some" 4 "U-937: 17.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" 0.1 0.2 0.1 0.6 0.2 4.3 0.6 0.3 0.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 4.7 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 23.9 0.9 0.2 0.1 0.7 1.7 1.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 17.6 0.0 69.8 4.0 18.9 0.0 2.2 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.2 6.2 0.1 1.1 0.0 0.0 1.1 0.1 0.2 0.3 0.4 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.9 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.2 4.5 0.7 0.0 0.0 0.2 0.0 1.2 0.4 0.0 0.0 0.3 1.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.1 1.5 3.8 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 3.7 0.1 0.0 0.4 0.2 0.2 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 SIGLEC11 ENSG00000161640 "Sialic acid binding Ig like lectin 11" Q96RL6 19 49948985-49961172 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 23.1;ovary: 65.5" "Group enriched" "Detected in some" 7 "Granulosa cells: 196.9;Theca cells: 192.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 6 "granulocytes: 1.4;monocytes: 1.3" "Cell line enriched" "Detected in single" 16 "HEL: 10.1" "HPA052132, HPA060278" Approved Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" Nucleoplasm "HPA052132: , HPA060278: AB_2684240" "unprognostic (1.07e-1)" "unprognostic (2.85e-3)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (3.35e-2)" "unprognostic (9.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.20e-1)" "unprognostic (8.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.41e-1)" "unprognostic (9.95e-3)" "unprognostic (5.38e-2)" 1.1 7.3 0.5 1.8 0.8 0.4 0.4 0.4 0.7 0.3 0.6 0.5 0.8 0.3 0.2 0.1 0.9 0.3 0.4 0.6 0.6 0.4 1.7 1.7 0.6 1.4 1.0 65.5 2.7 0.1 0.2 1.8 1.3 0.2 0.4 0.2 0.3 0.2 0.2 0.2 1.0 1.2 0.8 23.1 4.7 1.5 1.6 0.1 0.2 0.1 0.0 0.6 0.2 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 10.1 0.1 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.3 1.4 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.1 0.5 0.8 0.4 0.7 0.6 0.6 1.4 1.0 1.3 0.8 1.6 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 19.6 0.0 0.6 0.2 0.3 1.0 0.0 0.0 0.0 1.1 0.1 4.3 0.0 0.3 0.0 196.9 5.3 0.6 7.9 0.0 0.0 0.0 0.0 26.8 0.2 0.1 0.0 6.1 0.0 5.6 1.3 0.0 0.0 0.0 0.0 2.7 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 7.5 1.7 0.7 0.0 0.1 0.1 0.2 192.3 0.0 0.0 SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 330.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 31.6;Endometrial stromal cells: 23.9;Enteroendocrine cells: 45.2;Glandular and luminal cells: 52.0;Hepatic stellate cells: 24.7" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Endometrium - Transcription" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" 1.5 0.1 0.1 0.0 0.2 0.0 0.3 0.2 0.1 1.4 0.2 0.2 0.1 2.7 0.1 0.0 0.5 0.6 0.7 0.0 0.1 23.8 0.0 0.1 3.7 0.1 0.1 0.1 1.2 0.2 0.3 0.3 0.2 0.1 0.4 0.0 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 6.1 0.5 0.2 0.0 330.3 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.4 3.9 0.0 1.5 5.9 0.1 0.3 0.4 0.2 0.0 0.0 1.9 0.6 1.1 0.0 0.3 23.9 0.0 0.0 0.0 0.3 13.7 0.1 11.9 31.6 23.9 1.5 45.2 0.0 0.5 0.2 0.0 1.5 1.5 52.0 0.0 0.1 24.7 0.1 0.1 0.0 0.7 0.7 2.0 0.6 0.3 2.9 3.7 0.2 3.6 0.0 0.0 0.1 0.0 0.0 3.8 1.4 0.2 0.0 0.0 0.3 0.0 0.3 1.9 0.2 0.0 0.0 4.4 0.6 1.1 0.0 0.1 0.0 0.4 0.5 0.3 0.1 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 TPCN2 TPC2 ENSG00000162341 "Two pore segment channel 2" Q8NHX9 11 69048932-69136316 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.5;Melanocytes: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016561, HPA027080" Supported Approved Nucleoli NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA016561: AB_1858207, HPA027080: AB_10600917" "unprognostic (1.29e-1)" "unprognostic (1.53e-2)" "unprognostic (1.39e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (7.60e-2)" "unprognostic (7.04e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.49e-4)" "unprognostic (4.15e-2)" "unprognostic (1.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-3)" "unprognostic (5.01e-2)" "unprognostic (4.88e-2)" 5.8 3.8 2.2 4.8 2.9 4.4 5.2 4.8 3.1 8.9 0.2 11.7 7.6 8.9 3.2 4.6 8.5 3.8 3.9 2.2 1.3 7.5 11.1 4.5 5.8 0.7 0.2 5.8 3.6 2.7 4.2 3.0 0.8 7.2 3.9 4.4 4.1 5.7 4.2 10.0 7.2 4.8 0.1 6.3 4.7 3.2 1.5 3.0 4.3 1.4 4.2 6.3 5.9 3.2 4.6 8.8 3.5 4.9 2.7 3.0 10.5 3.6 3.9 4.7 2.4 8.5 12.4 3.5 5.0 6.9 3.2 9.6 3.2 5.8 2.0 2.7 3.3 7.7 13.7 1.9 3.2 6.5 8.5 4.0 3.2 2.2 2.8 2.4 4.9 8.4 4.7 16.7 2.7 6.9 4.4 9.4 2.4 11.5 3.1 4.6 3.3 6.8 5.1 8.0 2.8 3.6 5.9 11.4 17.0 4.3 7.0 9.1 5.2 3.5 4.5 6.4 4.0 6.8 2.9 4.0 7.7 5.5 8.3 2.9 10.2 2.6 0.9 9.9 0.8 2.4 1.8 2.1 7.7 1.8 1.8 1.9 7.0 6.2 11.7 3.1 2.7 4.4 2.2 2.9 4.8 3.1 2.2 1.3 0.7 0.2 0.8 0.1 1.5 3.2 4.5 9.6 1.5 10.1 6.7 4.0 2.7 3.0 2.2 1.8 2.8 2.5 3.1 5.7 2.3 12.9 2.1 2.6 6.1 4.4 17.6 7.2 17.7 2.1 5.6 4.2 0.0 8.2 30.5 8.6 4.8 4.0 8.6 3.4 2.5 7.3 5.3 18.4 11.9 0.0 22.4 2.6 2.0 12.6 5.5 2.7 6.2 10.2 35.6 4.7 7.7 2.5 3.1 26.2 4.5 4.8 2.6 6.8 8.3 1.5 8.8 9.1 0.8 4.9 6.6 5.1 5.7 2.2 4.4 1.9 3.4 1.9 3.6 3.2 3.6 2.1