Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCA10 EST698739 ENSG00000154263 "ATP binding cassette subfamily A member 10" Q8WWZ4 17 69147214-69244846 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "ovary: 18.3" "Cell type enhanced" "Detected in many" "Early spermatids: 231.0;Excitatory neurons: 91.9;Fibroblasts: 64.3;Inhibitory neurons: 112.4;Late spermatids: 93.1;Microglial cells: 187.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.3;HUVEC TERT2: 1.3;RT4: 1.3;U-2197: 2.1" HPA014535 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014535: AB_1844426" "unprognostic (1.45e-4)" "unprognostic (3.17e-1)" "unprognostic (7.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.52e-2)" "unprognostic (1.17e-2)" "unprognostic (3.78e-2)" "unprognostic (1.40e-1)" "unprognostic (4.51e-3)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "unprognostic (4.91e-1)" "unprognostic (2.70e-4)" "unprognostic (5.23e-3)" "unprognostic (6.98e-2)" "unprognostic (4.37e-2)" "unprognostic (9.86e-3)" 8.7 1.7 2.2 0.0 3.1 0.0 10.4 4.8 6.6 4.1 2.4 2.8 1.1 3.2 2.6 2.7 12.7 3.5 7.2 2.9 2.3 1.8 4.5 3.0 0.6 4.0 2.3 18.3 2.7 0.4 2.6 0.2 4.7 2.2 4.0 3.4 5.6 0.6 6.4 4.6 3.0 1.9 1.6 1.1 2.4 3.5 3.8 0.8 5.5 2.3 0.7 3.2 4.2 3.8 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 1.3 0.2 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.1 4.8 6.6 2.9 2.3 4.0 2.3 4.7 1.6 3.8 3.8 4.3 0.0 3.2 2.6 0.3 1.0 0.5 1.1 1.2 6.7 1.8 2.3 3.9 1.5 0.2 0.0 25.0 0.0 1.2 6.9 0.0 0.6 231.0 2.1 0.7 1.9 4.9 0.0 91.9 0.2 0.0 64.3 2.0 3.3 0.0 6.9 0.4 1.8 0.1 0.0 112.4 3.7 0.0 0.0 3.3 93.1 51.0 1.0 1.8 187.4 1.6 1.9 4.1 26.2 13.5 0.4 0.4 11.7 0.7 0.3 5.6 0.5 3.1 9.0 0.0 6.1 4.5 8.1 2.6 1.1 0.4 0.0 0.6 18.9 0.7 0.5 ABCA8 KIAA0822 ENSG00000141338 "ATP binding cassette subfamily A member 8" O94911 17 68867289-68955392 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 231.5;Granulosa cells: 117.3;Leydig cells: 502.6;Microglial cells: 162.1;Oligodendrocytes: 406.6;Skeletal myocytes: 216.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 31.9;ASC TERT1: 69.6;HSkMC: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044914 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA044914: AB_10964859" "unprognostic (2.58e-2)" "unprognostic (2.76e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.04e-1)" "unprognostic (6.84e-2)" "unprognostic (1.47e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (5.22e-2)" "unprognostic (6.68e-2)" "unprognostic (8.76e-2)" "unprognostic (1.42e-3)" "unprognostic (3.52e-3)" "unprognostic (1.88e-1)" "unprognostic (3.29e-1)" "unprognostic (6.14e-3)" 39.1 30.5 12.6 2.8 28.1 0.0 21.3 21.0 18.3 10.0 9.6 16.4 6.2 11.9 15.6 7.6 23.7 16.9 42.1 13.6 16.1 9.5 33.7 18.2 1.1 28.2 19.8 51.5 5.7 3.8 11.1 9.0 29.0 9.5 16.9 9.2 14.8 8.6 12.3 6.2 11.8 6.6 20.7 12.4 14.3 19.5 18.4 4.5 17.0 26.7 3.0 16.3 14.6 58.1 0.0 0.0 3.9 0.0 31.9 69.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 12.0 0.0 0.0 53.5 0.0 0.8 0.0 0.4 6.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 28.1 21.0 18.3 13.6 16.1 28.2 19.8 29.0 20.7 18.4 58.1 22.6 51.3 1.1 0.7 0.0 6.0 1.8 0.0 2.8 5.0 0.7 1.0 18.8 0.0 4.3 0.0 2.1 0.2 0.3 0.0 0.0 0.0 4.8 0.4 14.0 6.8 0.0 0.0 0.5 0.0 0.1 231.5 3.1 0.3 1.3 117.3 5.7 48.1 1.1 5.0 0.6 0.0 0.0 1.9 9.4 19.4 502.6 2.6 1.8 162.1 0.0 100.3 0.0 0.5 406.6 0.0 0.0 70.3 1.9 0.4 0.0 0.1 0.0 3.3 39.5 216.6 44.5 5.1 1.7 2.5 4.7 0.3 2.1 60.9 0.0 0.4 ABCA9 EST640918 ENSG00000154258 "ATP binding cassette subfamily A member 9" Q8IUA7 17 68974488-69060949 "Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.5;Fibroblasts: 86.6;Inhibitory neurons: 73.2;Leydig cells: 96.3;Microglial cells: 227.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 21.8;ASC TERT1: 47.7;HSkMC: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052113, HPA054823" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA052113: AB_2732573, HPA054823: AB_2682615" "unprognostic (3.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.21e-1)" "unprognostic (9.75e-2)" "unprognostic (4.46e-1)" "unprognostic (5.64e-3)" "unprognostic (4.51e-4)" "unprognostic (1.83e-2)" "unprognostic (1.94e-3)" "unprognostic (7.86e-2)" "unprognostic (3.26e-3)" "unprognostic (3.51e-1)" "unprognostic (7.77e-6)" "unprognostic (5.32e-4)" "unprognostic (7.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.96e-3)" 33.7 4.1 2.8 1.4 5.1 1.8 22.3 7.7 8.0 14.7 6.3 12.4 1.8 11.2 8.9 4.8 20.6 8.2 22.6 3.0 1.4 2.7 11.9 8.8 2.3 3.1 1.2 27.4 3.5 2.3 4.9 1.2 4.5 3.3 4.0 8.4 9.0 2.8 13.1 9.2 6.6 6.6 1.2 1.6 7.8 5.2 3.5 2.5 11.1 10.6 1.1 10.9 12.7 7.7 0.2 0.4 0.8 0.8 21.8 47.7 0.6 0.4 0.4 0.0 0.4 0.5 0.5 0.6 0.2 0.8 0.3 0.5 0.4 0.7 0.2 0.3 0.4 0.6 2.4 0.6 2.3 0.9 1.3 17.0 0.5 3.6 0.3 0.9 4.8 0.6 0.8 1.3 0.1 0.3 0.3 2.1 0.3 0.2 0.4 2.2 0.1 0.3 0.3 1.9 0.7 0.6 0.5 0.3 0.3 0.4 0.4 0.8 2.0 1.3 0.5 2.3 0.5 1.0 0.5 0.4 0.4 0.5 2.4 0.5 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.4 0.2 0.0 0.1 0.0 0.0 2.8 5.1 7.7 8.0 3.0 1.4 3.1 1.2 4.5 1.2 3.5 7.7 7.4 0.0 1.5 2.6 0.5 1.8 0.3 0.1 1.2 3.9 0.7 0.8 3.9 1.5 0.1 0.0 0.0 0.0 0.6 0.9 0.0 0.1 1.3 0.4 2.1 2.6 0.0 0.0 55.5 0.0 0.0 86.6 2.0 1.4 0.0 2.2 18.5 11.4 0.3 0.0 73.2 0.1 0.0 1.3 5.1 3.6 96.3 4.9 0.0 227.7 0.0 7.9 1.0 6.0 10.9 0.2 0.0 15.4 0.2 0.1 0.3 0.0 1.7 5.6 13.1 26.3 7.1 1.3 0.8 1.3 1.6 0.0 0.5 26.3 0.1 0.3 ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.6" "Group enriched" "Detected in many" 9 "Early spermatids: 295.1;Late spermatids: 1030.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.5;T-47d: 3.3;U-266/70: 3.0;U-266/84: 2.8" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" 1.2 0.6 0.8 0.1 0.7 0.0 0.5 1.5 1.1 0.1 0.3 0.1 0.0 0.3 0.4 0.1 0.2 0.2 0.5 0.7 0.8 0.3 3.3 0.1 0.2 0.9 0.7 0.4 0.1 0.4 0.2 0.0 0.9 0.7 0.0 0.4 1.5 0.2 1.9 0.0 0.1 0.3 0.9 0.1 0.2 21.6 0.9 0.0 0.4 1.7 0.1 0.0 0.0 0.9 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.2 3.0 2.8 0.0 0.1 0.1 0.1 0.0 0.2 0.8 0.6 0.0 0.2 0.5 0.3 0.3 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.7 1.5 1.1 0.7 0.8 0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.0 0.0 4.9 1.0 0.0 3.3 0.0 2.8 5.1 1.9 2.8 3.1 1.5 0.0 0.0 8.4 0.2 0.9 0.2 0.0 0.3 295.1 0.4 0.6 1.9 0.0 3.2 0.6 0.2 0.0 1.3 0.0 0.5 1.3 1.6 2.5 3.9 0.1 0.0 0.8 0.2 0.0 0.3 0.3 1030.5 6.5 1.2 0.0 1.9 0.5 8.1 3.1 2.0 2.2 0.0 0.0 5.7 0.5 3.6 0.2 3.0 0.7 4.9 0.0 2.4 1.2 70.5 3.9 0.3 0.3 0.0 1.8 0.3 0.2 2.2 ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Fibroblasts: 213.8;Leydig cells: 97.3;Muller glia cells: 93.7;Skeletal myocytes: 106.8" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 437.3;hTEC/SVTERT24-B: 840.8;hTERT-HME1: 818.4;TIME: 1405.8;U-2197: 311.0" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" NA NA 550000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" 41.3 9.9 3.9 57.0 9.7 0.2 23.1 0.8 4.1 56.4 3.1 36.5 5.3 49.5 10.7 35.1 46.9 97.9 44.5 3.8 26.6 12.2 7.8 68.7 25.9 3.4 5.7 89.4 12.7 3.0 4.7 51.9 7.3 8.7 56.2 57.5 13.7 12.3 6.7 14.0 15.4 72.0 5.6 12.4 25.5 17.1 6.7 7.9 25.0 41.1 39.9 96.7 23.7 9.1 1.3 0.3 0.1 0.0 37.0 437.3 0.4 91.9 90.2 171.4 79.9 0.0 0.2 0.9 0.4 25.0 0.3 0.0 0.1 1.0 278.2 0.8 0.7 2.4 1.6 0.0 23.7 0.5 0.1 26.6 1.0 840.8 818.4 3.6 267.1 0.0 0.5 1.3 158.6 0.0 0.5 0.3 0.1 0.0 87.5 0.4 0.7 0.7 54.0 0.2 0.2 0.6 0.0 0.6 0.1 0.8 0.3 0.1 1405.8 37.7 0.4 311.0 19.7 1.0 0.0 0.0 43.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 9.7 0.8 4.1 3.8 26.6 3.4 5.7 7.3 5.6 6.7 9.1 9.1 57.7 5.5 26.1 0.3 15.9 1.5 5.8 4.6 1.2 0.6 1.8 9.7 10.0 39.8 18.4 2.1 0.5 0.1 0.4 0.0 0.3 10.3 1.2 30.6 23.6 1.2 0.0 2.6 0.4 0.4 213.8 9.7 2.4 3.8 0.2 16.1 0.1 0.9 0.0 47.0 0.8 0.0 0.6 23.2 8.8 97.3 1.8 19.6 7.5 0.0 93.7 0.0 1.5 3.3 1.9 5.4 27.8 0.7 1.5 0.2 9.0 5.0 3.7 0.0 106.8 17.5 0.1 0.3 3.9 19.9 0.7 2.1 3.6 1.0 2.9 AC007906.2 ENSG00000277639 "Novel protein" 16 53035690-53052873 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "choroid plexus: 86.7;fallopian tube: 77.8" "Group enriched" "Detected in some" 7 "Endometrial ciliated cells: 224.8;Respiratory ciliated cells: 209.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 31.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 8.3;ASC TERT1: 7.0;BEWO: 11.6;HSkMC: 7.1;RPTEC TERT1: 7.5" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.97e-2)" "unprognostic (8.34e-3)" "unprognostic (1.63e-1)" "unprognostic (5.38e-3)" "unprognostic (1.70e-1)" "unprognostic (5.75e-2)" "unprognostic (2.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "unprognostic (2.25e-2)" "unprognostic (1.54e-2)" "unprognostic (5.02e-2)" "unprognostic (6.07e-2)" "unprognostic (5.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-2)" "unprognostic (4.46e-3)" 1.0 0.3 1.6 0.4 1.1 0.0 6.0 1.0 0.4 11.2 86.7 4.5 0.6 2.8 1.4 9.0 77.8 10.5 1.4 2.9 2.0 16.5 1.3 9.5 0.1 6.5 10.4 0.3 11.6 0.3 0.3 1.5 3.9 9.4 5.1 0.0 3.5 2.7 1.0 4.7 0.4 0.8 3.4 0.0 0.9 0.2 2.5 0.8 0.3 1.0 1.2 6.8 2.6 1.6 0.1 2.5 4.1 2.1 8.3 7.0 11.6 1.2 0.9 0.1 0.0 0.3 1.7 0.2 2.1 1.7 0.8 0.7 0.0 1.6 0.5 0.2 0.1 0.0 0.1 0.6 1.6 0.0 1.8 7.1 6.2 2.3 0.7 2.3 1.7 0.1 0.1 0.1 3.8 0.1 0.1 0.0 4.6 0.4 0.6 1.0 0.0 0.0 7.5 1.6 0.2 0.0 0.3 0.0 0.1 3.4 0.8 0.1 2.0 2.7 2.7 0.1 0.0 0.0 0.0 0.0 3.3 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.1 1.0 0.4 2.9 2.0 6.5 10.4 3.9 3.4 2.5 1.6 0.1 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.7 12.7 0.0 0.0 30.3 25.8 0.0 0.1 0.5 0.0 5.9 4.9 0.0 224.8 1.7 0.8 0.0 0.0 0.0 0.0 0.3 3.2 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 209.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 51.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 25.5;HEL: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 4.8 2.1 14.7 1.8 30.5 5.2 4.5 24.6 22.5 7.2 5.6 6.4 1.2 7.8 2.2 3.7 6.1 4.2 2.6 14.9 22.7 6.0 0.8 6.7 0.9 47.1 26.3 7.4 2.1 0.3 11.4 8.7 34.3 3.6 2.1 2.2 2.7 2.4 1.0 2.3 2.6 4.7 25.5 4.6 2.3 2.8 28.6 1.3 4.1 1.0 1.0 3.0 5.0 51.3 0.5 1.0 25.5 5.1 4.7 9.5 1.1 0.9 0.3 1.9 3.2 1.5 4.6 0.7 1.8 4.2 11.8 0.5 4.8 4.0 1.8 2.9 8.1 19.4 4.9 0.1 3.7 0.2 2.8 11.4 1.9 5.0 2.7 9.1 6.1 3.1 9.8 8.9 2.4 0.0 1.4 2.2 6.2 0.0 9.7 0.0 1.1 0.5 5.6 0.4 14.8 5.6 4.0 2.1 1.1 9.9 1.1 1.2 6.8 2.6 3.3 1.8 4.4 0.7 1.0 0.0 9.9 1.0 1.6 0.0 1.8 0.0 3.4 1.5 1.1 0.2 1.6 2.1 1.0 0.5 0.8 1.2 0.3 2.9 1.3 0.8 1.7 1.3 14.7 30.5 24.6 22.5 14.9 22.7 47.1 26.3 34.3 25.5 28.6 51.3 12.0 3.2 5.5 7.5 4.5 3.2 5.5 9.7 6.2 2.4 3.5 2.7 5.6 5.7 6.9 5.5 0.0 20.3 31.1 6.1 0.0 5.2 52.1 23.8 12.5 13.5 1.8 31.5 87.9 8.2 12.0 17.8 4.6 5.1 11.4 20.6 10.4 0.2 18.2 0.0 95.8 0.7 10.2 7.2 16.4 72.8 5.9 17.0 3.6 23.4 9.4 4.0 9.2 56.3 407.6 5.5 18.7 8.6 15.7 1.3 0.0 0.6 21.4 1.2 19.7 5.3 6.9 4.9 2.8 1.1 2.6 22.2 14.1 3.7 1.4 3.6 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AK5 ENSG00000154027 "Adenylate kinase 5" Q9Y6K8 1 77282019-77559966 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 121.0" "Cell type enhanced" "Detected in many" "Early spermatids: 150.5;Excitatory neurons: 403.7;Inhibitory neurons: 167.3;Oligodendrocytes: 706.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 13.6;naive CD4 T-cell: 16.3" "Group enriched" "Detected in many" 12 "dendritic cells: 13.6;T-cells: 16.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 93.7;BJ: 67.8;fHDF/TERT166: 77.5;LHCN-M2: 189.9;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019128, HPA057255" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Centriolar satellite" "HPA019128: AB_1844682, HPA057255: AB_2683383" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (1.13e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (6.04e-2)" "unprognostic (2.20e-1)" "unprognostic (2.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-2)" "prognostic favorable (3.88e-4)" "unprognostic (3.56e-3)" "unprognostic (6.17e-4)" "unprognostic (1.18e-1)" "unprognostic (5.96e-2)" "unprognostic (6.76e-2)" 1.0 1.6 75.9 1.5 101.2 3.9 18.9 19.4 115.0 1.3 0.8 2.6 1.0 0.7 0.6 1.0 1.0 1.0 1.0 121.0 31.5 1.4 0.1 0.4 2.3 27.2 30.2 0.5 1.6 0.7 3.4 1.2 25.6 2.3 1.0 3.0 3.0 2.1 0.3 2.0 1.0 0.8 31.0 2.1 2.4 9.4 31.7 0.8 1.1 0.8 1.5 0.7 0.7 81.1 0.2 3.6 2.9 0.1 34.8 93.7 1.2 67.8 14.4 10.8 4.6 0.5 1.7 0.6 0.5 77.5 4.4 0.4 0.2 0.0 5.5 2.6 0.7 0.5 1.2 0.4 1.8 0.6 0.2 11.6 0.5 2.1 4.3 37.9 31.5 0.3 0.9 0.7 189.9 0.7 0.0 0.6 3.9 18.4 24.5 1.7 7.1 1.6 29.3 1.1 15.3 3.5 0.2 0.2 4.4 0.3 0.3 0.5 7.9 26.1 58.4 1.6 2.2 15.2 14.7 0.3 5.2 3.5 9.8 1.2 0.8 0.1 3.8 0.2 0.5 0.9 3.6 1.9 13.6 0.9 16.3 9.1 0.6 0.2 0.2 1.5 1.7 2.3 75.9 101.2 19.4 115.0 121.0 31.5 27.2 30.2 25.6 31.0 31.7 81.1 0.7 0.0 0.0 10.7 0.4 0.3 0.4 0.0 1.2 1.3 54.0 27.3 1.1 0.0 0.0 1.8 0.0 1.9 5.6 0.3 7.9 0.3 150.5 1.1 0.1 1.3 12.0 0.8 403.7 0.6 56.3 1.5 1.1 1.7 0.0 0.0 0.4 0.0 2.4 13.5 167.3 0.3 0.0 0.0 0.6 29.2 1.2 0.4 3.6 41.2 1.9 0.0 47.4 60.8 706.6 0.1 1.1 0.7 0.1 2.9 0.0 7.8 0.0 0.3 0.0 1.2 6.3 10.2 91.0 0.0 0.3 2.9 4.2 0.1 0.2 0.1 AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.8" "Cell type enriched" "Detected in some" 4 "Early spermatids: 80.6" "Cancer enhanced" "Detected in single" "glioma: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.1;hTCEpi: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: AB_10610980, HPA030271: AB_10600873, HPA030272: AB_10601342" "unprognostic (4.93e-2)" "unprognostic (1.72e-1)" "unprognostic (5.52e-2)" "unprognostic (2.00e-3)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-5)" "unprognostic (8.15e-2)" "unprognostic (5.95e-2)" "unprognostic (2.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.24e-1)" "unprognostic (3.00e-8)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (5.75e-2)" "unprognostic (8.22e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.7 0.0 0.0 1.6 0.0 1.5 0.1 0.0 1.8 2.5 0.5 0.9 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.2 80.6 0.3 5.1 1.4 0.0 0.0 1.0 0.2 0.8 3.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.7 0.0 0.0 0.3 17.8 2.5 0.1 1.8 0.0 0.0 0.4 0.0 3.5 3.1 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.9 0.6 1.4 0.1 0.1 0.7 0.1 0.7 0.5 0.0 ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 857.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 857.0;monocytes: 940.8;Proximal tubular cells: 882.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.0;myeloid DC: 213.2" "Group enriched" "Detected in many" 4 "dendritic cells: 213.2;monocytes: 212.0" "Cell line enhanced" "Detected in many" "ASC diff: 86.8;HHSteC: 97.0;OE19: 152.2;SK-BR-3: 201.0;THP-1: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" 303.8 102.4 139.7 39.8 146.1 29.2 77.2 136.5 163.5 25.0 123.3 73.3 73.7 30.1 21.3 73.6 32.3 37.4 111.3 132.2 139.7 177.7 857.7 111.6 18.7 140.7 144.9 42.0 23.3 2.6 23.3 7.0 141.1 34.6 72.3 29.2 32.4 29.5 130.8 127.9 74.8 30.2 143.0 20.6 101.5 13.0 151.8 27.1 30.8 165.7 52.9 50.0 29.0 144.5 8.8 13.1 18.7 31.9 86.8 13.0 60.9 9.3 16.8 4.3 3.1 23.5 12.1 0.5 45.3 20.8 11.9 16.2 0.1 4.6 2.7 0.6 6.1 0.7 8.4 64.7 97.0 0.9 0.9 23.9 22.6 14.8 0.3 17.7 26.9 0.9 17.9 3.0 4.1 0.5 1.0 23.4 24.8 152.2 2.1 0.6 0.4 1.9 31.4 0.6 7.5 23.1 22.8 201.0 0.2 33.7 20.3 92.1 1.1 0.4 16.5 0.6 0.4 5.5 3.0 25.7 22.0 0.8 0.4 6.5 212.0 51.1 0.7 93.0 0.9 6.2 0.3 0.7 213.2 5.2 0.7 0.5 10.7 3.4 25.4 70.6 0.5 123.5 139.7 146.1 136.5 163.5 132.2 139.7 140.7 144.9 141.1 143.0 151.8 144.5 27.7 147.4 242.7 51.2 22.6 60.0 205.2 311.1 80.8 78.7 35.0 23.7 378.9 165.8 243.1 66.2 18.8 62.4 48.6 260.3 399.2 127.5 4.3 27.8 24.5 66.2 55.2 42.1 11.7 218.0 127.5 103.1 200.3 47.7 30.9 29.0 139.6 857.0 129.2 35.3 18.2 231.0 101.7 278.5 124.1 10.6 79.9 189.3 35.6 26.2 940.8 130.2 8.2 14.1 6.8 130.2 366.5 149.0 12.5 84.4 384.3 882.0 89.4 42.6 46.0 46.0 67.6 3.0 3.9 105.1 124.7 42.1 13.1 81.0 272.6 150.4 ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "ovary: 22.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 19.4;Langerhans cells: 11.3;Leydig cells: 27.7;Melanocytes: 7.2;Peritubular cells: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "ASC diff: 2.7" "Region enhanced" "Detected in some" "spinal cord: 3.3" HPA038516 Uncertain "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" 4.3 0.2 0.1 0.0 0.2 0.0 5.5 0.2 0.4 0.2 0.4 0.3 0.1 0.0 4.4 0.2 0.3 0.2 2.7 0.2 0.2 0.0 0.0 0.9 0.1 0.2 0.1 22.4 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.4 0.2 0.4 2.4 0.2 0.0 0.2 0.0 0.1 1.6 0.1 0.0 0.7 1.9 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 2.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.1 0.5 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.0 0.0 2.1 0.9 0.6 0.8 0.0 0.0 2.7 0.0 0.1 19.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.0 0.0 0.0 0.0 11.3 0.8 27.7 0.1 7.2 4.7 0.0 0.2 0.0 1.0 0.2 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.2 1.0 0.2 0.2 0.0 5.5 0.1 0.5 5.7 0.0 0.0 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ARHGEF25 "GEFT, p63RhoGEF" ENSG00000240771 "Rho guanine nucleotide exchange factor 25" Q86VW2 12 57610180-57617245 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 151.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.8;Leydig cells: 24.8;Peritubular cells: 45.9;Sertoli cells: 26.3;Smooth muscle cells: 38.9" "Cancer enhanced" "Detected in all" "glioma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 59.1;RH-30: 129.7;SH-SY5Y: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052016 Approved NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" "HPA052016: AB_2681695" "unprognostic (8.43e-2)" "unprognostic (4.24e-3)" "unprognostic (2.13e-3)" "unprognostic (6.95e-3)" "unprognostic (8.12e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.45e-2)" "unprognostic (2.39e-2)" "unprognostic (4.63e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (4.20e-7)" "unprognostic (1.41e-2)" "unprognostic (2.03e-1)" "unprognostic (6.82e-3)" "unprognostic (3.22e-3)" 34.4 12.0 30.7 10.7 38.7 0.1 29.1 38.5 72.1 64.5 12.6 151.2 10.3 92.8 44.3 29.6 85.5 23.6 24.6 72.0 21.7 17.7 5.0 21.7 6.2 20.6 21.1 58.2 8.5 9.4 26.4 9.4 20.8 60.6 19.5 13.2 13.9 80.4 11.4 12.0 34.4 68.8 17.3 20.1 45.0 10.6 22.5 2.1 14.1 13.8 4.9 84.3 51.4 40.5 0.8 8.9 41.6 26.1 0.1 0.0 3.3 12.7 37.4 16.5 20.2 5.2 8.1 3.5 10.7 23.4 7.7 0.4 16.2 0.7 13.9 11.7 13.9 7.4 6.1 11.4 11.6 0.2 19.2 11.5 3.5 7.5 1.1 59.1 6.5 2.0 15.5 16.0 12.2 3.0 2.7 0.3 26.5 0.4 0.4 0.0 129.7 0.7 0.7 0.7 24.1 58.7 2.4 1.2 4.8 14.8 4.3 8.9 0.0 14.8 14.0 9.7 4.7 33.5 5.4 0.1 12.4 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 38.7 38.5 72.1 72.0 21.7 20.6 21.1 20.8 17.3 22.5 40.5 5.6 0.0 0.0 8.5 0.0 2.0 1.8 0.2 4.6 17.7 1.8 8.6 11.6 0.0 0.6 0.0 2.1 0.2 0.6 0.0 0.0 0.5 0.2 1.1 20.8 4.4 0.0 0.0 15.3 1.4 0.5 12.6 0.5 0.6 0.0 2.6 6.8 0.0 0.5 8.4 8.5 0.0 0.0 0.0 1.7 1.5 24.8 0.2 0.0 8.4 0.0 5.4 2.1 3.0 1.6 0.3 0.0 45.9 0.3 0.8 0.0 0.4 0.0 2.8 26.3 6.3 38.9 1.4 1.4 0.9 1.1 0.3 0.5 9.6 0.0 0.4 ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" 21.0 47.2 9.6 5.3 11.1 1.6 18.5 10.0 9.2 24.8 6.2 14.5 3.7 18.9 12.2 3.5 13.2 14.8 12.3 8.9 11.1 10.1 26.9 14.2 2.3 13.5 10.5 19.3 24.0 10.7 9.0 6.5 10.5 12.3 6.2 2.8 20.2 18.6 10.5 7.4 7.9 9.7 10.1 27.8 9.5 4.3 12.1 3.1 15.8 6.1 1.7 13.8 13.3 12.1 3.3 2.9 30.8 5.8 24.5 37.1 1.1 11.4 28.1 12.1 9.4 1.4 7.5 0.0 1.8 20.9 12.2 5.0 2.6 3.7 4.3 6.6 1.1 4.6 3.4 9.0 3.5 3.0 16.5 15.5 2.4 10.3 3.1 22.6 0.0 0.0 1.4 1.3 9.6 0.3 0.0 8.6 8.1 0.8 0.5 1.0 23.2 1.4 7.6 4.1 0.7 11.6 6.4 0.6 8.9 6.0 2.7 10.1 5.9 25.4 17.5 11.9 5.9 2.6 0.0 0.0 8.8 4.2 7.5 0.0 1.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.0 0.4 9.6 11.1 10.0 9.2 8.9 11.1 13.5 10.5 10.5 10.1 12.1 12.1 12.7 6.4 5.0 32.0 2.5 4.8 8.0 5.8 1.8 9.2 6.6 11.3 13.4 47.1 3.2 14.7 0.0 1.4 0.5 10.0 19.6 21.2 1.0 17.6 13.1 11.0 7.8 1.7 0.3 10.2 0.9 20.4 18.3 3.5 38.0 11.6 8.2 31.5 14.1 5.0 6.2 9.1 4.1 46.9 14.6 2.3 24.2 22.0 23.2 17.8 23.6 24.6 1.0 21.1 8.9 16.4 6.6 24.0 3.1 6.3 1.0 7.1 1.7 6.8 26.3 18.6 21.9 3.1 2.8 0.6 4.4 1.2 3.5 14.6 18.7 6.1 ARL6IP5 "DERP11, GTRAP3-18, HSPC127, JWA, PRAF3, Yip6b" ENSG00000144746 "ADP ribosylation factor like GTPase 6 interacting protein 5" O75915 3 69084937-69106092 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015540, CAB019321" Supported Approved "Endoplasmic reticulum" NA NA 1100000 "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" "CAB019321: , HPA015540: AB_1852061" "unprognostic (8.01e-2)" "unprognostic (1.71e-1)" "unprognostic (8.09e-2)" "unprognostic (1.51e-3)" "unprognostic (2.65e-1)" "unprognostic (3.51e-1)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (3.06e-1)" "unprognostic (3.72e-3)" "unprognostic (1.31e-2)" "unprognostic (7.23e-2)" "unprognostic (2.05e-3)" "unprognostic (3.60e-1)" "unprognostic (4.44e-2)" "unprognostic (3.42e-2)" "unprognostic (1.31e-2)" 157.7 130.6 91.0 109.9 95.9 67.8 139.7 100.6 156.0 123.0 83.1 87.3 59.1 72.8 104.4 78.3 90.5 102.1 216.3 91.1 105.6 88.5 80.3 125.5 138.3 100.6 93.4 74.2 55.3 83.4 47.6 88.8 106.8 129.6 85.2 135.0 159.6 90.5 183.2 48.5 66.1 100.4 104.1 100.3 72.5 34.9 98.3 92.3 71.2 186.8 130.0 111.8 61.0 113.3 86.9 59.0 71.1 52.8 361.4 335.2 89.7 87.9 196.5 66.7 77.4 30.1 205.9 17.0 28.9 151.1 124.8 67.0 59.2 100.8 57.0 339.5 55.2 59.6 91.1 45.8 92.9 51.4 280.5 243.6 177.5 61.5 77.3 235.0 206.0 55.7 26.6 156.7 163.6 50.3 56.0 67.0 18.5 200.2 55.1 48.6 65.0 159.1 330.5 143.1 17.8 47.0 87.0 93.5 119.5 69.7 61.7 80.2 203.7 44.1 34.8 112.5 96.1 139.4 208.5 31.7 146.0 126.0 72.8 697.4 388.2 650.2 332.4 357.6 257.1 397.7 462.4 427.6 275.7 336.1 391.2 409.5 162.0 298.4 315.1 176.0 530.4 933.9 91.0 95.9 100.6 156.0 91.1 105.6 100.6 93.4 106.8 104.1 98.3 113.3 101.1 176.3 132.0 34.6 183.6 72.8 70.6 275.5 108.7 201.9 214.9 174.5 422.0 95.8 185.0 93.8 187.7 305.8 212.7 146.7 25.4 281.4 20.8 144.9 79.5 121.4 42.0 89.8 45.9 214.4 379.2 254.8 64.2 233.4 336.6 75.7 150.3 72.5 292.0 122.8 70.7 57.1 270.6 260.0 402.1 18.9 207.2 275.4 272.1 35.6 476.6 235.7 272.9 49.8 97.0 244.2 95.7 261.8 93.4 93.6 91.7 77.8 155.0 272.4 190.7 190.3 125.4 7.3 4.3 207.8 73.9 178.4 292.2 133.6 77.8 94.0 ARMC2 "bA787I22.1, DKFZp434P0714" ENSG00000118690 "Armadillo repeat containing 2" Q8NEN0 6 108848416-108974476 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.4" "Cell type enhanced" "Detected in many" "Astrocytes: 80.0;Early spermatids: 117.7;Excitatory neurons: 86.1;Inhibitory neurons: 69.3;Late spermatids: 145.3;Respiratory ciliated cells: 61.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025809, HPA053696" Enhanced Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA025809: AB_1845032, HPA053696: AB_2682233" "unprognostic (4.42e-2)" "unprognostic (9.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (4.00e-4)" "unprognostic (1.13e-2)" "unprognostic (3.74e-2)" "unprognostic (5.71e-2)" "unprognostic (5.19e-5)" "unprognostic (7.55e-2)" "unprognostic (1.55e-3)" "unprognostic (9.38e-2)" "unprognostic (6.44e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" 5.3 3.8 3.8 3.9 7.8 8.8 7.0 0.9 6.8 6.6 31.8 2.9 1.8 7.5 7.6 3.4 20.4 5.2 9.3 3.0 2.3 3.6 2.6 8.6 4.2 2.7 5.9 5.4 2.4 9.4 6.7 6.9 1.2 3.9 4.6 26.7 3.4 4.7 4.0 5.2 3.4 4.1 1.1 5.9 5.0 33.4 7.6 3.8 10.6 1.3 4.2 2.4 2.7 3.6 3.5 2.1 10.1 6.5 4.9 5.9 2.2 2.1 2.9 5.3 7.0 3.2 3.0 5.5 2.6 3.4 8.1 3.0 5.6 4.2 9.1 1.5 4.9 5.1 5.2 3.4 2.6 8.0 2.2 6.8 5.8 6.1 1.7 7.1 5.0 16.6 2.2 8.4 5.5 2.7 7.0 7.3 3.2 3.4 2.6 7.8 8.3 4.3 4.9 4.1 14.0 5.2 7.3 1.8 5.1 5.6 3.7 4.1 2.5 4.4 2.3 3.8 2.9 3.8 5.5 4.7 7.6 5.5 5.6 3.7 2.1 0.6 2.0 3.0 1.8 0.8 1.5 2.2 1.7 1.9 0.9 2.2 6.0 2.9 2.4 2.8 4.7 1.0 3.8 7.8 0.9 6.8 3.0 2.3 2.7 5.9 1.2 1.1 7.6 3.6 2.0 9.6 3.7 80.0 3.4 1.0 1.1 1.9 0.6 2.0 1.2 1.5 6.8 1.5 10.9 0.0 0.0 1.5 2.9 0.3 0.0 1.2 117.7 33.0 2.7 2.2 1.8 2.1 86.1 1.0 2.1 3.0 1.5 1.8 0.0 2.8 0.7 0.3 3.9 1.7 69.3 0.4 4.1 4.4 0.4 145.3 6.8 3.1 5.4 11.2 0.5 1.7 3.1 35.7 24.4 0.7 0.0 10.1 5.9 0.6 0.4 1.8 61.8 4.9 0.0 4.2 4.2 41.5 6.3 1.9 1.4 0.5 5.1 2.5 0.6 0.7 ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Collecting duct cells: 12.9;Endometrial ciliated cells: 10.2;Endometrial stromal cells: 7.7;Granulosa cells: 26.0;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.7;AN3-CA: 6.1;fHDF/TERT166: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" 1.2 2.5 2.3 0.6 3.6 0.7 0.8 8.5 3.5 1.8 0.0 0.7 0.5 3.0 1.8 0.8 2.1 1.8 3.1 2.6 2.1 8.3 0.8 0.7 0.4 11.5 5.1 4.3 1.0 3.6 1.3 0.4 12.8 1.6 1.0 1.2 0.7 1.4 0.2 1.0 0.7 2.3 1.0 0.5 1.4 2.2 1.6 0.2 1.5 1.9 0.3 1.2 0.9 0.7 0.0 0.0 9.7 6.1 4.7 1.7 0.0 1.9 1.5 0.3 0.3 0.5 0.1 0.0 0.6 10.8 1.2 0.0 2.9 0.0 0.4 0.1 1.0 0.0 0.0 0.5 0.2 0.0 4.8 1.8 0.0 0.2 0.2 2.7 0.5 0.8 0.1 0.3 1.2 0.3 0.0 0.0 4.5 0.0 2.0 1.4 0.3 2.5 3.9 0.3 1.1 0.0 0.1 0.0 0.3 2.7 0.2 0.2 0.1 1.3 3.5 0.5 2.6 0.3 0.2 0.0 3.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.6 8.5 3.5 2.6 2.1 11.5 5.1 12.8 1.0 1.6 0.7 15.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 12.9 0.0 0.2 0.7 0.0 0.0 2.1 0.0 10.2 7.7 2.3 0.0 0.0 0.0 1.3 0.4 3.0 0.0 2.4 0.0 26.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 44.5 0.0 0.0 ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 53.3;lymphoid tissue: 19.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Endothelial cells: 12.9;Erythroid cells: 51.3;Hepatic stellate cells: 66.0;Hepatocytes: 30.2" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.0;HEL: 12.1;Hep G2: 7.3;HUVEC TERT2: 27.0" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" NA NA 17000000 "Cluster 85: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" 2.6 2.7 0.3 1.1 0.5 4.6 1.8 0.1 0.4 0.9 0.4 0.6 0.0 0.8 0.3 0.9 2.1 9.0 9.0 0.3 1.1 3.6 53.3 3.2 8.6 0.5 0.4 0.5 2.3 0.3 0.1 7.0 0.4 0.3 0.5 0.3 0.7 0.4 0.3 0.3 0.6 1.1 0.2 19.0 0.3 0.2 0.4 1.9 3.6 0.2 2.3 0.6 0.5 0.6 0.0 0.0 0.2 6.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 7.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.1 0.4 0.3 1.1 0.5 0.4 0.4 0.2 0.4 0.6 0.7 0.0 1.1 0.7 0.2 0.3 0.8 0.0 0.0 2.4 0.2 0.1 1.5 15.7 0.0 1.8 12.5 0.9 0.1 0.0 0.0 0.9 0.4 0.2 0.1 12.9 0.0 51.3 0.2 1.9 2.5 1.9 0.0 0.1 0.0 0.0 66.0 30.2 0.1 0.0 0.2 0.0 0.0 4.7 1.3 0.3 1.8 0.1 1.8 0.0 0.0 0.3 1.0 0.0 0.3 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 11.8 6.6 0.5 1.2 0.1 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.4 ASB9 "DKFZP564L0862, FLJ20636, MGC4954" ENSG00000102048 "Ankyrin repeat and SOCS box containing 9" Q96DX5 X 15235288-15270467 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 16.8;liver: 17.4;lymphoid tissue: 11.7;pancreas: 9.5;testis: 25.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 41.1;Proximal tubular cells: 38.1;Spermatogonia: 126.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 25.8;EFO-21: 20.1;PC-3: 53.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003014, HPA003060, CAB004997" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "CAB004997: AB_426132, HPA003014: AB_1078226, HPA003060: AB_1078225" "unprognostic (8.26e-3)" "unprognostic (1.70e-1)" "unprognostic (8.82e-2)" "unprognostic (2.25e-3)" "unprognostic (1.31e-1)" "unprognostic (2.70e-2)" "unprognostic (6.44e-2)" "unprognostic (1.45e-2)" "unprognostic (2.39e-1)" "unprognostic (9.23e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (2.88e-1)" "unprognostic (2.27e-2)" "unprognostic (9.22e-2)" "unprognostic (1.27e-1)" "unprognostic (2.57e-1)" 2.3 0.8 0.7 0.4 0.6 2.4 1.5 0.9 1.0 2.3 0.6 1.7 1.6 1.3 0.8 1.5 2.2 1.9 2.5 0.6 0.5 16.8 17.4 3.5 0.9 1.0 0.6 0.6 9.5 0.6 0.5 3.1 0.8 1.0 2.3 0.1 3.8 0.8 0.5 1.8 1.0 2.3 0.6 11.7 4.0 25.8 0.7 4.1 2.2 1.4 1.2 1.4 0.8 0.7 1.5 25.8 0.2 2.4 0.0 1.1 0.7 0.6 2.7 2.9 1.1 5.8 0.1 0.3 20.1 0.9 14.1 7.5 0.0 1.2 1.9 5.4 0.6 6.2 12.6 12.5 0.0 0.0 0.0 6.6 0.2 0.2 0.1 0.3 9.4 1.9 0.1 5.9 1.7 1.8 5.4 0.1 12.2 3.6 53.5 0.1 11.1 5.8 8.0 4.2 2.6 2.6 0.7 1.4 9.0 1.3 0.1 0.7 8.1 0.1 1.8 1.3 3.9 0.4 5.1 0.2 0.8 0.0 14.2 0.5 0.6 0.0 0.0 0.0 0.7 0.0 0.1 0.0 1.6 0.1 1.2 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.7 0.6 0.9 1.0 0.6 0.5 1.0 0.6 0.8 0.6 0.7 0.7 10.7 0.0 0.0 0.0 1.1 1.9 1.1 0.7 2.2 0.0 0.8 0.9 0.5 12.8 1.0 0.0 0.0 0.1 0.1 0.9 41.1 1.1 2.4 1.2 0.3 11.1 10.7 7.2 0.1 2.0 0.1 1.2 2.6 0.3 1.3 3.4 20.0 12.6 4.7 0.0 0.3 0.3 2.0 4.6 4.4 8.0 1.8 3.3 16.0 1.0 0.3 0.0 0.0 0.0 0.1 0.9 0.5 0.7 0.0 0.6 0.0 38.1 4.8 0.0 0.0 0.0 0.6 1.6 126.5 2.4 3.1 0.1 0.3 5.7 1.6 0.6 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;kidney: 38.2" "Cell type enhanced" "Detected in many" "Leydig cells: 49.7;Melanocytes: 46.2;Oligodendrocytes: 217.0;Peritubular cells: 48.2;Proximal enterocytes: 37.5;Proximal tubular cells: 74.8" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 5.4;ASC TERT1: 4.1;CACO-2: 3.8;HSkMC: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" 13.9 4.3 25.9 1.8 46.4 1.8 4.1 27.6 40.9 7.5 14.2 4.3 11.2 4.5 6.0 4.9 5.5 3.6 2.7 25.8 27.7 38.2 15.0 3.5 1.5 30.4 35.4 2.9 1.0 0.8 0.8 3.5 29.5 4.1 4.9 2.8 1.8 5.0 11.9 5.2 15.6 3.1 24.7 5.4 4.4 6.6 42.4 0.6 2.1 15.0 0.7 6.3 4.3 69.0 0.2 0.1 0.5 0.5 5.4 4.1 0.3 0.2 0.1 0.2 0.1 3.8 0.2 0.6 0.2 0.7 0.3 0.3 0.3 0.1 0.2 2.0 0.1 0.4 0.7 0.2 0.5 0.4 0.4 7.5 0.3 0.4 0.1 0.1 0.1 0.4 0.3 1.1 0.2 0.2 0.2 0.6 0.4 0.2 0.3 0.3 0.3 0.6 0.2 1.1 0.4 0.3 1.1 0.3 0.9 0.4 0.3 0.2 0.4 0.6 0.4 0.4 0.3 0.7 0.4 0.4 0.2 0.4 0.5 1.1 0.1 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 0.7 0.3 0.1 0.2 0.1 0.0 25.9 46.4 27.6 40.9 25.8 27.7 30.4 35.4 29.5 24.7 42.4 69.0 5.1 9.6 1.5 12.1 0.1 5.2 1.5 1.6 6.2 5.5 2.1 0.8 1.3 2.8 1.0 25.8 0.0 0.0 0.0 0.3 7.9 0.2 5.0 0.1 4.1 1.1 2.4 2.7 0.6 0.2 0.1 15.0 2.0 0.2 0.0 0.1 3.9 11.5 0.2 8.4 0.4 0.8 2.0 0.8 1.5 2.5 49.7 0.8 46.2 3.7 0.0 4.1 0.0 1.5 217.0 0.0 2.5 48.2 0.2 0.4 37.5 74.8 0.1 0.5 0.0 8.5 11.6 11.1 0.6 0.7 1.7 0.1 0.4 28.3 1.8 2.7 ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 95.3;smooth muscle: 110.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 67.2;Fibroblasts: 94.6;Microglial cells: 24.4;Sertoli cells: 39.5;Smooth muscle cells: 73.5;Suprabasal keratinocytes: 27.0" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enhanced" "Detected in single" "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "ASC TERT1: 16.0;BJ hTERT+: 5.7;HHSteC: 23.2;HSkMC: 4.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 2100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" 29.6 7.6 1.2 5.7 1.7 0.1 11.8 2.3 2.0 40.9 0.9 25.5 9.6 69.6 9.7 10.1 16.9 65.9 95.3 1.2 1.2 11.2 41.1 14.3 3.0 1.3 1.2 7.1 13.4 3.8 2.5 4.3 1.6 4.7 11.3 0.2 3.2 11.7 7.8 12.1 17.6 110.5 1.0 2.3 12.0 1.2 1.8 2.5 11.1 19.8 5.5 13.4 5.0 1.7 0.1 0.0 0.0 0.0 1.4 16.0 0.2 2.6 5.7 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 23.2 0.2 0.0 4.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 1.2 1.7 2.3 2.0 1.2 1.2 1.3 1.2 1.6 1.0 1.8 1.7 12.9 0.0 1.1 0.3 0.1 67.2 0.1 0.0 0.0 0.4 0.4 0.1 8.5 0.0 0.6 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 4.2 6.8 0.0 0.0 2.0 0.0 0.1 94.6 0.5 0.2 1.3 0.1 13.9 0.4 0.2 0.0 1.7 0.0 0.0 0.0 13.5 0.6 5.9 0.8 14.2 24.4 0.0 0.1 0.0 1.5 1.1 0.0 0.0 1.9 0.3 0.0 0.0 0.0 0.7 0.6 39.5 4.3 73.5 0.0 0.1 0.3 27.0 0.0 1.7 0.3 0.0 0.0 ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.2" "Cell type enhanced" "Detected in many" "Astrocytes: 354.6;Excitatory neurons: 370.0;Inhibitory neurons: 1011.0;Late spermatids: 228.2;Oligodendrocyte precursor cells: 900.3;Oligodendrocytes: 225.9" "Cancer enhanced" "Detected in all" "prostate cancer: 15.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 37.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Nucleoplasm "HPA027035: AB_1845122" "unprognostic (3.25e-2)" "unprognostic (2.70e-2)" "unprognostic (7.41e-3)" "unprognostic (5.42e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (2.94e-1)" "unprognostic (2.80e-1)" "unprognostic (3.40e-2)" "unprognostic (2.93e-1)" "prognostic favorable (6.66e-16)" "unprognostic (3.28e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" 3.3 9.8 26.1 2.7 26.3 3.6 4.3 39.0 36.0 5.3 9.0 5.2 3.4 3.2 3.9 2.2 8.0 2.5 22.5 27.0 25.8 5.5 4.1 2.2 2.4 29.3 36.2 2.8 6.7 3.1 11.6 1.8 28.7 25.2 3.2 13.4 5.8 11.3 7.3 2.4 4.1 2.8 21.4 2.4 5.6 17.6 35.0 6.0 1.8 5.6 1.8 3.2 3.5 39.2 3.7 12.0 4.3 7.1 7.6 7.0 15.4 5.7 2.3 2.5 2.8 8.1 4.4 8.8 6.1 3.8 9.3 1.3 11.5 0.6 3.1 4.8 2.9 3.1 5.8 17.0 3.0 1.8 6.2 9.5 1.1 7.8 0.7 5.4 1.8 10.5 3.9 5.9 7.9 3.8 4.1 1.4 13.2 10.6 6.4 4.9 27.5 2.5 8.0 12.3 6.3 37.9 6.8 2.0 4.8 14.5 15.5 1.3 3.5 5.9 9.1 5.6 4.9 9.0 5.0 8.3 10.5 2.0 25.8 2.5 0.4 0.5 2.8 0.3 3.6 1.5 3.1 2.4 0.2 1.6 3.0 2.5 1.9 5.9 0.6 0.9 8.8 1.0 26.1 26.3 39.0 36.0 27.0 25.8 29.3 36.2 28.7 21.4 35.0 39.2 0.6 6.4 8.9 354.6 1.1 1.3 3.2 0.4 1.2 4.9 4.2 4.8 22.7 2.8 5.0 1.8 10.4 0.4 1.0 0.4 3.9 0.8 122.5 4.7 5.5 1.3 12.6 0.4 370.0 1.1 0.4 4.9 4.1 0.7 6.3 37.0 0.7 2.9 3.2 10.1 1011.0 1.0 0.0 0.0 1.6 228.2 2.8 1.0 0.0 36.5 0.2 3.0 0.0 900.3 225.9 0.5 2.1 5.7 3.6 11.7 5.7 6.9 11.7 5.1 0.0 1.9 2.0 7.7 13.2 0.3 0.6 0.3 3.8 1.9 1.8 2.2 ATL1 "AD-FSP, FSP1, SPG3, SPG3A" ENSG00000198513 "Atlastin GTPase 1" Q8WXF7 14 50532509-50634017 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 138.6;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 136.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 22.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.9" "Cell line enhanced" "Detected in many" "HDLM-2: 19.8;SCLC-21H: 17.1;SH-SY5Y: 15.4;SiHa: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027550 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA027550: AB_10600983" "unprognostic (2.06e-2)" "unprognostic (7.57e-3)" "unprognostic (1.82e-1)" "unprognostic (7.93e-2)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (7.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (4.95e-2)" "unprognostic (1.23e-2)" 4.1 5.6 29.1 3.3 33.2 0.2 11.3 18.8 42.8 5.7 2.2 8.1 3.9 9.0 2.9 5.3 6.5 4.8 2.1 37.1 30.3 4.0 0.3 4.3 1.7 25.2 21.5 10.5 3.7 1.9 7.7 0.5 29.6 8.3 5.6 9.5 13.2 8.6 1.1 9.6 4.9 15.6 24.9 1.1 4.6 8.7 25.0 1.1 2.5 2.2 1.8 6.7 5.3 30.0 1.2 1.1 4.8 4.6 0.3 0.0 3.4 5.7 9.6 6.2 7.4 0.0 4.1 3.7 2.5 0.1 4.5 1.4 8.4 1.1 2.4 19.8 1.8 1.2 0.8 0.3 0.2 0.2 3.1 3.6 1.9 8.6 1.6 0.3 0.4 4.2 0.1 0.5 8.7 0.4 1.2 0.6 4.4 1.4 1.5 0.6 12.1 0.4 1.7 2.5 17.1 15.4 18.9 1.1 0.6 0.0 0.0 2.1 1.3 6.0 4.6 0.0 2.9 0.9 4.7 1.7 3.9 0.2 0.2 22.9 0.1 4.9 2.5 0.0 0.5 3.8 0.9 2.1 1.2 1.1 2.1 4.2 0.3 0.6 0.5 2.8 0.4 2.0 29.1 33.2 18.8 42.8 37.1 30.3 25.2 21.5 29.6 24.9 25.0 30.0 3.0 6.4 2.6 31.6 3.7 5.1 6.2 10.3 6.2 27.8 18.1 16.3 1.9 5.7 6.6 5.5 0.0 0.4 6.7 9.3 0.0 10.6 31.4 4.2 5.4 4.8 7.2 0.4 138.6 13.1 1.1 14.6 5.6 2.3 6.3 1.2 5.0 0.0 1.6 11.8 95.5 1.9 2.0 0.0 3.6 5.7 13.4 5.5 8.8 20.6 1.3 23.0 2.1 81.4 136.7 7.2 6.0 17.0 5.2 3.9 13.2 3.4 14.2 8.6 19.7 4.5 10.8 31.9 5.7 4.1 5.5 0.1 3.8 0.2 3.6 3.3 ATP1B2 AMOG ENSG00000129244 "ATPase Na+/K+ transporting subunit beta 2" P14415 17 7646627-7657770 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "brain: 395.1;retina: 614.8" "Group enriched" "Detected in many" 5 "Astrocytes: 207.3;Bipolar cells: 330.2;Cone photoreceptor cells: 250.2;Muller glia cells: 303.2;Rod photoreceptor cells: 226.1" "Cancer enriched" "Detected in many" 17 "glioma: 200.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.6;HAP1: 2.9;K-562: 4.5;SuSa: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010698 Supported NA NA 160000 "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "HPA010698: AB_1845174" "unprognostic (9.39e-2)" "unprognostic (1.86e-2)" "unprognostic (3.89e-3)" "unprognostic (4.96e-3)" "unprognostic (3.90e-3)" "unprognostic (9.33e-2)" "unprognostic (4.86e-1)" "unprognostic (5.93e-2)" "unprognostic (5.43e-2)" "unprognostic (1.29e-2)" "prognostic favorable (1.05e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (4.60e-3)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (3.79e-2)" 6.1 10.1 212.3 0.9 251.6 11.4 5.0 268.1 288.8 13.3 25.8 9.1 1.2 8.8 17.4 2.2 12.3 3.6 8.6 196.9 250.0 10.1 2.7 4.2 1.7 353.9 395.1 29.5 2.5 4.5 45.3 4.5 282.6 6.6 2.7 614.8 1.9 7.5 4.3 2.3 3.5 5.5 256.3 5.0 3.8 5.5 364.8 0.8 4.6 5.3 1.1 4.6 7.7 174.7 0.0 0.0 9.6 0.4 0.3 0.2 0.1 0.1 0.0 0.3 0.2 0.4 0.0 0.3 0.2 0.1 0.2 0.3 2.9 0.2 0.1 0.1 1.2 0.2 0.1 0.1 0.1 0.0 0.9 0.5 0.0 0.3 0.0 0.1 0.0 0.2 4.5 0.5 0.0 0.2 0.2 0.3 2.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 1.8 0.0 0.1 0.0 5.7 0.1 0.2 0.0 0.1 0.7 0.0 0.2 0.4 0.1 0.0 0.9 0.2 0.2 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 212.3 251.6 268.1 288.8 196.9 250.0 353.9 395.1 282.6 256.3 364.8 174.7 8.5 0.0 0.0 207.3 1.8 1.9 0.4 0.0 1.8 330.2 2.3 6.2 3.7 2.8 0.0 0.0 250.2 0.0 1.1 6.7 0.0 0.2 0.2 0.8 8.3 7.7 0.0 49.2 2.9 0.0 0.1 5.9 7.7 0.6 0.0 1.0 11.4 0.2 0.3 18.5 38.8 2.4 2.0 0.8 0.9 2.3 18.6 1.6 0.0 7.5 0.2 303.2 0.0 45.8 1.6 0.0 0.0 46.3 0.8 0.5 0.5 0.2 0.0 226.1 26.3 2.4 50.0 1.2 6.1 1.6 1.1 0.3 1.6 0.5 2.6 0.2 ATRNL1 "ALP, FLJ45344, KIAA0534" ENSG00000107518 "Attractin like 1" Q5VV63 10 115093365-115948999 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 91.1" "Group enriched" "Detected in many" 13 "Excitatory neurons: 2134.6;Inhibitory neurons: 1473.4;Oligodendrocyte precursor cells: 1456.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 91.1;white matter: 58.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.4;RH-30: 18.4;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038070 Approved Nucleoplasm,Mitochondria NA NA 160000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" "HPA038070: AB_10697237" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (5.88e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.88e-2)" "unprognostic (5.17e-2)" "unprognostic (4.06e-2)" "unprognostic (2.18e-2)" "unprognostic (2.50e-2)" "unprognostic (1.04e-3)" "unprognostic (3.10e-2)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (2.08e-3)" 0.7 10.7 3.8 0.2 9.5 0.0 1.0 0.0 91.1 0.9 0.0 2.4 0.3 6.2 0.3 0.5 1.0 0.2 1.8 18.3 0.0 2.8 1.5 0.1 0.4 0.0 0.2 9.7 1.3 2.1 5.8 1.9 1.0 3.1 0.2 6.3 1.0 3.8 2.8 0.2 0.8 5.8 0.0 0.3 0.4 12.6 0.0 0.4 1.0 0.0 0.4 0.6 1.0 58.7 0.0 0.6 6.3 21.4 0.0 0.0 0.0 0.1 0.6 3.9 4.6 0.2 0.2 0.0 1.5 0.5 5.1 0.0 1.6 0.0 4.0 0.1 4.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 6.4 0.0 11.3 0.0 5.3 10.4 0.2 9.9 0.0 9.1 0.0 0.1 7.5 18.4 11.4 3.9 0.0 3.6 10.5 0.0 0.1 0.4 4.3 1.8 0.0 0.0 0.0 2.7 0.1 3.3 14.2 0.0 4.6 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.5 0.0 91.1 18.3 0.0 0.0 0.2 1.0 0.0 0.0 58.7 0.0 0.0 0.0 55.8 0.8 0.6 0.1 0.8 0.6 35.4 2.1 0.5 2.5 0.0 0.1 0.0 2.1 0.1 0.2 0.2 0.0 0.7 45.6 0.8 1.5 1.5 0.0 0.0 2134.6 0.4 0.0 5.3 0.0 1.8 0.0 24.9 21.0 0.1 3.0 10.1 1473.4 0.0 0.0 1.9 0.4 47.8 1.5 0.3 0.0 128.4 0.0 4.3 0.0 1456.7 34.2 0.3 0.0 0.7 0.0 0.1 0.0 0.5 0.1 4.7 0.0 2.4 2.6 46.6 11.5 0.0 0.1 0.3 0.1 53.1 0.0 0.1 BBS9 "B1, PTHB1" ENSG00000122507 "Bardet-Biedl syndrome 9" Q3SYG4 7 33109557-33877180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 125.7;Excitatory neurons: 162.6;Inhibitory neurons: 159.0;Microglial cells: 266.1;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021289 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA021289: AB_1845286" "unprognostic (1.18e-1)" "unprognostic (2.18e-1)" "unprognostic (3.13e-1)" "unprognostic (3.17e-1)" "unprognostic (4.86e-1)" "unprognostic (2.34e-1)" "unprognostic (1.19e-3)" "unprognostic (2.27e-1)" "unprognostic (8.68e-2)" "unprognostic (4.13e-2)" "unprognostic (7.22e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.86e-4)" "unprognostic (2.75e-2)" "unprognostic (1.28e-1)" "unprognostic (5.20e-1)" "unprognostic (6.90e-3)" 6.9 8.0 9.1 2.5 10.7 1.9 6.7 8.8 8.6 10.8 13.7 6.3 0.7 5.8 4.2 4.7 6.9 3.8 6.4 7.9 8.5 6.8 4.3 5.8 3.4 9.9 9.8 9.5 3.9 10.4 13.2 4.5 10.0 6.9 3.0 21.9 6.3 5.7 3.5 5.5 4.1 4.4 9.5 4.8 4.4 9.9 10.6 5.5 11.4 3.6 3.0 6.2 8.5 10.6 3.1 3.2 6.0 6.4 12.1 11.0 2.7 3.7 11.7 3.4 10.1 2.7 5.2 4.7 4.4 8.5 9.6 3.9 3.1 7.0 8.3 2.3 4.8 0.9 5.6 3.2 5.3 1.4 2.1 10.1 3.8 6.6 2.6 10.5 8.8 9.9 2.8 5.5 7.3 2.9 3.0 2.5 3.3 4.6 4.4 3.6 2.0 2.7 4.4 1.4 2.7 5.2 7.6 3.3 6.6 8.8 8.0 0.8 4.0 3.3 4.9 6.9 2.3 6.8 10.3 6.6 8.7 2.3 5.4 4.9 2.9 4.5 4.9 4.6 5.5 4.4 4.5 5.3 2.4 4.4 4.3 5.4 1.1 7.4 2.3 0.9 5.6 2.9 9.1 10.7 8.8 8.6 7.9 8.5 9.9 9.8 10.0 9.5 10.6 10.6 7.3 3.2 3.7 125.7 6.9 3.7 6.7 3.1 7.4 6.8 3.6 3.4 14.2 2.8 5.0 5.5 29.2 3.6 4.3 1.8 3.9 3.7 28.6 17.6 7.2 7.4 3.6 3.8 162.6 1.5 4.6 7.3 5.1 3.6 0.0 5.9 5.3 2.5 3.7 5.0 159.0 2.7 8.2 2.5 2.9 6.6 4.1 3.4 1.8 266.1 2.2 7.8 4.1 238.8 366.6 1.5 0.5 5.7 8.1 1.6 1.8 3.8 15.6 51.2 0.0 6.0 5.5 25.6 14.7 6.0 3.3 2.5 7.1 4.6 2.3 4.3 BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 795.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 223.5;Peritubular cells: 782.7;Sertoli cells: 1485.7;Smooth muscle cells: 401.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 312.6;BJ hTERT+: 400.8;fHDF/TERT166: 568.9;HSkMC: 283.9;hTEC/SVTERT24-B: 235.2;HUVEC TERT2: 561.2;U-138 MG: 249.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 3300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" 165.8 213.0 54.1 93.1 57.6 0.3 118.0 51.2 91.5 371.0 69.5 69.3 22.0 234.4 83.7 45.8 143.7 326.1 795.8 56.1 48.7 396.5 347.9 477.3 42.4 50.6 50.8 94.9 67.9 26.6 144.1 199.1 53.2 184.2 24.8 1.1 107.7 135.5 32.4 118.9 48.8 213.2 45.5 352.1 51.6 69.9 64.6 15.9 250.0 46.7 35.9 126.8 180.0 65.4 0.0 0.0 29.7 0.1 31.5 70.5 1.1 312.6 400.8 56.7 18.6 39.5 0.0 0.0 56.9 568.9 2.0 0.1 0.0 0.0 10.2 0.0 0.0 0.0 0.6 3.9 27.0 0.0 0.2 283.9 2.2 235.2 10.7 29.0 561.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.0 1.5 0.3 0.2 0.0 0.1 0.0 0.6 0.4 0.0 0.0 1.1 11.8 1.3 0.0 120.0 249.5 2.3 1.0 1.5 0.9 0.1 0.0 0.1 0.3 114.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 57.6 51.2 91.5 56.1 48.7 50.6 50.8 53.2 45.5 64.6 65.4 30.5 3.2 5.6 5.9 0.6 104.1 1.3 7.3 5.7 0.2 1.2 5.6 16.1 4.3 2.5 9.2 0.0 15.5 0.7 0.0 1.9 2.7 1.8 1.4 28.3 45.2 0.0 5.3 0.1 0.2 50.0 180.0 7.7 1.1 3.8 8.4 223.5 1.6 4.4 3.3 0.1 0.0 0.0 4.0 43.6 13.5 147.9 3.0 35.6 25.3 2.0 0.1 0.0 20.6 0.0 1.2 0.0 782.7 0.0 3.0 0.0 0.8 1.6 0.2 1485.7 3.1 401.3 0.8 1.2 1.8 54.1 56.9 3.0 7.7 0.0 1.6 BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.3;lung: 5.5;urinary bladder: 9.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 32.2;Distal enterocytes: 68.9;Granulosa cells: 104.0;Paneth cells: 32.8;Proximal enterocytes: 25.2" "Group enriched" "Detected in some" 4 "lung cancer: 4.2;urothelial cancer: 7.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 10.3;Daudi: 16.3;RT4: 13.5;SK-BR-3: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (3.36e-2)" "unprognostic (2.73e-3)" "unprognostic (9.11e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-4)" "unprognostic (2.26e-2)" "unprognostic (3.86e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" 1.5 0.4 0.3 0.3 0.2 0.8 1.2 0.2 0.3 0.4 0.1 9.3 3.2 0.0 0.1 0.0 0.9 2.0 0.0 0.1 0.6 0.1 0.0 5.5 0.3 0.7 0.7 2.5 0.0 0.0 0.0 0.0 0.5 0.2 6.8 0.5 1.3 0.0 0.0 0.3 7.2 0.5 0.6 0.0 1.1 0.1 1.4 0.0 0.0 0.6 1.5 9.5 0.2 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 0.0 0.0 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 13.5 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.7 0.7 0.5 0.6 1.4 0.0 0.0 3.2 32.2 0.0 0.2 0.1 0.5 0.7 0.0 2.2 0.1 0.0 1.3 0.0 15.1 0.0 0.0 0.0 0.0 68.9 0.0 0.0 0.0 0.9 0.1 0.3 0.0 0.0 1.6 0.0 0.0 2.1 0.0 0.0 0.0 104.0 0.0 0.0 0.0 0.0 5.6 5.0 6.1 0.0 1.2 0.0 0.9 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.2 32.8 0.0 0.0 0.5 25.2 0.1 9.4 0.1 0.0 0.3 1.2 0.2 0.3 0.0 0.4 0.0 0.0 0.1 14.1 3.8 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;intestine: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 266.7;Excitatory neurons: 333.7;Inhibitory neurons: 129.7;Oligodendrocyte precursor cells: 1079.2" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" 0.3 1.7 19.8 0.6 16.8 0.0 1.4 18.7 19.2 0.2 0.0 6.6 4.6 0.2 3.0 1.7 0.4 1.6 5.3 27.1 25.8 2.3 0.0 1.2 0.0 12.5 15.7 0.0 0.0 0.0 0.2 0.0 12.4 6.8 6.7 0.7 1.6 5.1 0.1 0.1 17.9 0.6 13.1 0.0 0.2 3.4 26.0 0.1 2.1 0.0 0.1 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 16.8 18.7 19.2 27.1 25.8 12.5 15.7 12.4 13.1 26.0 10.4 0.0 0.0 0.0 266.7 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.4 2.3 0.0 0.0 3.7 0.0 0.0 0.0 2.0 3.9 0.0 63.3 0.0 0.0 0.1 1.2 0.0 333.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 129.7 2.8 0.0 0.0 0.0 10.5 0.0 0.1 0.0 8.4 0.0 0.0 0.0 1079.2 4.3 0.0 10.8 0.0 0.0 1.0 8.1 0.3 0.0 0.1 0.0 0.0 5.8 2.0 0.7 0.1 0.0 0.0 0.0 0.0 5.2 0.1 BST1 CD157 ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 139.8;intestine: 48.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.8;Macrophages: 33.3;monocytes: 80.1;Proximal enterocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 257.7;neutrophil: 292.7" "Group enriched" "Detected in many" 95 "dendritic cells: 78.9;granulocytes: 292.7;monocytes: 257.7" "Cell line enhanced" "Detected in many" "THP-1: 76.0;TIME: 40.4;U-937: 52.5;WM-115: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" NA NA 190000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" 21.2 2.7 1.9 13.7 2.1 139.8 9.4 2.1 4.7 11.0 1.6 8.3 48.6 6.3 2.9 4.6 7.9 18.2 19.1 2.1 2.0 17.0 8.5 12.7 7.1 1.9 1.4 9.3 3.1 1.7 1.3 13.7 2.2 3.7 9.7 1.0 3.9 4.6 2.7 5.0 29.3 9.7 0.8 18.6 3.2 2.7 3.0 3.9 4.9 6.8 3.5 16.8 7.4 3.3 0.6 10.5 1.2 1.0 28.8 7.0 1.6 21.0 2.1 20.4 22.2 0.3 12.1 0.8 1.9 12.2 0.6 0.3 3.3 0.5 17.2 0.8 0.7 5.6 0.8 0.6 6.7 7.2 15.1 5.7 1.5 12.9 1.0 0.9 3.0 5.0 0.7 0.5 12.5 0.3 2.3 4.3 2.7 0.9 2.2 0.8 1.8 0.5 0.5 0.6 1.4 4.3 0.4 0.7 14.2 1.2 0.5 76.0 40.4 0.6 1.0 7.9 1.1 0.6 0.2 0.7 2.7 52.5 44.8 41.8 257.7 20.8 1.1 97.4 1.7 2.2 0.9 0.8 78.9 0.9 1.1 0.7 292.7 0.4 73.9 26.6 1.0 109.8 1.9 2.1 2.1 4.7 2.1 2.0 1.9 1.4 2.2 0.8 3.0 3.3 5.4 3.2 3.7 1.3 0.3 4.6 0.8 0.1 1.8 0.6 1.2 2.0 1.5 2.8 1.0 1.8 0.0 16.0 5.5 3.7 1.9 4.4 4.4 8.0 9.9 3.8 1.2 2.5 0.7 2.5 24.0 22.5 0.0 16.2 15.9 20.6 6.4 2.1 40.8 0.0 0.7 8.1 0.0 26.3 11.5 1.2 3.1 33.3 14.2 3.7 80.1 0.6 3.1 0.5 3.6 1.1 11.9 2.2 0.4 0.6 79.0 9.6 3.0 0.2 6.6 3.9 15.5 2.5 1.4 1.7 3.0 7.1 1.8 1.4 23.2 3.3 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.4;salivary gland: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 161.6;Fibroblasts: 61.5;Late spermatids: 387.6;Muller glia cells: 227.2;Skeletal myocytes: 77.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 211 "U-266/84: 810.2" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 44100000 24000000 "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA064996: AB_2685399, HPA066011: AB_2685597" "unprognostic (7.71e-2)" "unprognostic (2.81e-3)" "unprognostic (5.83e-2)" "unprognostic (6.58e-2)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-3)" "unprognostic (5.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.89e-3)" "unprognostic (1.80e-1)" "unprognostic (9.38e-3)" "unprognostic (2.35e-1)" 7.3 0.5 4.1 1.7 5.0 0.6 6.8 6.8 4.0 3.6 2.6 11.2 3.5 2.7 1.0 33.4 3.0 5.9 0.9 3.9 7.0 4.8 1.1 4.1 0.8 5.3 4.3 1.4 1.7 0.3 1.3 0.6 4.5 2.2 10.0 23.7 52.0 4.9 2.2 2.3 8.9 23.3 5.8 0.7 10.7 11.4 4.2 1.0 1.6 9.9 0.4 13.2 3.6 5.1 0.7 0.1 0.2 0.3 0.0 0.1 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.9 0.2 0.0 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.7 0.8 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.8 3.2 0.0 0.0 0.0 1.1 0.1 0.0 0.1 0.2 0.2 1.6 0.0 0.1 0.6 0.1 0.0 3.8 0.6 0.1 1.0 0.0 1.0 0.9 810.2 1.3 0.0 0.8 3.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.1 5.0 6.8 4.0 3.9 7.0 5.3 4.3 4.5 5.8 4.2 5.1 2.3 3.2 2.0 0.0 2.0 5.7 0.6 0.4 1.8 5.1 3.0 2.3 1.0 8.6 0.8 3.7 0.0 0.9 1.5 0.7 1.9 1.2 161.6 2.6 1.0 7.2 1.8 1.3 0.0 1.4 0.5 61.5 1.5 2.6 0.0 1.8 0.4 1.3 1.3 8.4 0.0 1.4 2.0 0.6 9.6 387.6 1.8 1.1 7.2 0.0 0.3 227.2 1.0 0.0 0.0 0.5 1.5 2.6 0.2 0.8 0.8 2.1 1.2 11.9 0.0 77.5 4.5 6.2 2.0 1.1 5.8 0.4 1.3 1.0 2.0 0.5 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C20orf202 ENSG00000215595 "Chromosome 20 open reading frame 202" A1L168 20 1203454-1208279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 3.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Early spermatids: 3.6;Late spermatids: 2.1;Paneth cells: 1.3;Proximal enterocytes: 1.2;Sertoli cells: 6.6;Smooth muscle cells: 1.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.0" "Group enriched" "Detected in some" 15 "cerebellum: 8.0;olfactory bulb: 2.6" "Low region specificity" "Detected in many" HPA042786 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA042786: AB_10795760" "unprognostic (8.20e-2)" "unprognostic (1.66e-1)" "unprognostic (7.27e-2)" "unprognostic (2.73e-2)" "unprognostic (3.49e-3)" "unprognostic (1.92e-3)" "unprognostic (1.15e-2)" "unprognostic (7.41e-3)" "unprognostic (1.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (7.55e-2)" "unprognostic (5.82e-3)" "unprognostic (7.98e-2)" "unprognostic (5.70e-3)" "unprognostic (1.26e-1)" "unprognostic (7.24e-3)" 0.6 0.1 0.5 0.1 0.5 0.0 0.3 1.0 0.9 0.2 0.3 0.3 0.3 0.1 0.0 0.3 0.4 0.7 0.6 0.4 0.5 0.4 0.1 1.3 0.2 0.5 0.5 0.1 0.3 0.4 0.2 3.3 0.6 0.1 0.3 0.4 0.4 0.6 0.5 0.5 1.1 0.2 0.5 0.2 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.5 1.0 0.9 0.4 0.5 0.5 0.5 0.6 0.5 0.7 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 0.0 1.2 0.1 0.0 0.0 6.6 0.1 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 39.9" "Cell type enriched" "Detected in some" 21 "Theca cells: 41.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;HSkMC: 2.0;hTEC/SVTERT24-B: 2.0;SCLC-21H: 2.3;THP-1: 2.0;U-2197: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.64e-1)" "unprognostic (1.14e-1)" "unprognostic (8.77e-3)" "unprognostic (7.13e-6)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-1)" "unprognostic (4.81e-2)" "unprognostic (3.15e-2)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (2.10e-1)" "unprognostic (5.13e-10)" "unprognostic (1.95e-1)" "unprognostic (6.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" 0.6 0.7 1.5 0.0 2.2 0.0 0.3 2.3 1.2 0.1 0.8 0.1 0.1 0.2 0.1 0.2 0.1 0.4 1.2 0.5 2.2 0.1 0.1 0.3 0.2 5.5 2.6 0.7 0.0 0.0 0.7 0.1 4.5 0.3 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.2 4.3 0.1 0.0 39.9 2.3 0.0 0.1 0.0 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.2 0.1 0.0 2.0 0.0 0.0 0.5 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 2.2 2.3 1.2 0.5 2.2 5.5 2.6 4.5 4.3 2.3 6.6 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120952335-121050275 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "liver: 433.7" "Cell type enriched" "Detected in many" 16 "Hepatocytes: 538.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 28.4;Hep G2: 30.4" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029339 Supported "Secreted to blood" NA NA 113000000000 39000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" 2.9 1.7 2.5 1.1 3.4 2.2 2.5 2.4 2.6 3.0 3.5 2.8 3.9 2.7 2.7 1.6 3.0 1.5 1.3 2.2 2.6 4.8 433.7 7.0 2.1 2.9 2.9 3.3 14.9 2.6 3.1 0.9 3.2 3.2 1.6 3.5 1.4 2.2 0.5 3.8 3.9 1.9 2.8 1.5 5.8 1.6 2.8 1.2 2.0 1.2 1.7 2.6 2.1 4.5 1.6 28.4 6.4 11.3 8.0 9.2 0.2 3.4 3.5 0.9 2.0 0.8 2.8 4.1 0.1 1.8 3.8 11.0 0.3 0.3 1.5 0.9 0.0 1.8 1.5 30.4 1.5 1.0 0.7 4.1 0.5 2.0 3.7 1.8 1.0 1.6 0.7 3.8 2.2 5.6 0.4 0.2 1.7 7.0 10.9 2.5 2.8 0.4 1.7 0.8 1.6 6.5 1.6 0.0 2.7 4.4 2.2 3.7 1.3 2.8 0.2 7.5 3.4 2.3 1.8 1.7 2.2 3.8 6.8 0.0 0.3 0.4 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 3.4 2.4 2.6 2.2 2.6 2.9 2.9 3.2 2.8 2.8 4.5 0.8 6.4 28.6 30.0 3.5 1.0 1.0 0.5 1.8 4.8 2.2 1.3 0.8 32.9 7.1 1.8 0.0 0.1 0.1 0.4 1.9 0.2 1.8 1.1 2.2 1.4 0.0 12.0 7.3 0.4 0.0 2.9 2.0 0.8 0.0 3.1 7.5 538.3 1.9 6.7 9.4 1.0 0.0 16.3 1.0 2.8 3.1 3.5 0.0 6.5 2.3 3.2 2.1 25.6 25.4 0.7 3.8 9.1 0.1 0.7 1.0 6.8 3.8 2.6 0.0 4.0 1.6 7.5 2.5 2.0 1.3 0.0 1.4 2.8 2.0 0.6 C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2;fallopian tube: 9.1;parathyroid gland: 7.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 396.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HEK 293: 2.3;LHCN-M2: 2.7;RH-30: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044420, HPA053065" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: AB_10963791, HPA053065: AB_2682030" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (3.07e-1)" "unprognostic (2.85e-2)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (1.74e-1)" "unprognostic (8.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.80e-4)" "unprognostic (5.21e-2)" "unprognostic (8.87e-2)" "unprognostic (2.84e-4)" "unprognostic (1.33e-1)" 2.7 0.3 4.0 0.2 5.4 0.5 0.7 3.6 3.9 2.1 2.0 0.2 0.2 0.6 0.6 1.0 9.1 0.6 0.7 6.2 3.8 0.4 0.2 2.5 0.2 6.4 10.2 0.4 1.1 7.4 1.7 0.3 4.6 2.1 0.3 1.0 0.6 1.0 0.3 0.9 0.2 0.1 4.0 0.2 0.8 0.7 6.7 0.8 0.4 0.9 0.2 0.4 0.2 6.1 0.1 0.0 0.3 0.1 0.6 1.0 0.1 0.9 2.3 0.3 0.3 0.1 0.2 0.1 0.3 0.5 0.1 0.1 0.1 0.3 0.1 0.0 2.3 0.3 0.5 0.2 0.1 0.0 0.2 0.1 0.3 0.4 0.8 0.1 0.0 0.3 0.1 0.4 2.7 0.3 0.0 0.2 1.0 0.0 0.0 0.1 2.7 0.0 0.2 0.2 0.5 0.0 0.1 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.2 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.4 0.5 0.1 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.3 0.2 0.3 0.5 0.2 0.1 0.4 0.1 0.1 4.0 5.4 3.6 3.9 6.2 3.8 6.4 10.2 4.6 4.0 6.7 6.1 0.2 16.0 18.7 9.4 0.0 1.7 0.8 0.2 0.0 1.5 0.2 0.0 1.2 0.0 3.9 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.5 26.4 0.7 0.5 0.0 0.0 79.2 0.0 0.3 1.9 0.0 4.3 1.3 0.1 0.0 0.0 0.3 0.0 396.6 0.1 0.0 0.0 1.2 1.3 0.3 0.4 1.8 3.7 0.1 0.0 0.0 9.5 10.1 0.5 0.0 0.4 0.0 0.8 0.0 0.0 20.8 0.7 0.0 0.6 1.7 0.6 0.4 0.1 0.9 0.4 0.4 0.2 0.0 0.4 CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 37.9;Muller glia cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.3;fHDF/TERT166: 27.0;hTERT-HME1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA012618: AB_1846000" "unprognostic (1.62e-2)" "unprognostic (2.10e-3)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-2)" "unprognostic (4.59e-5)" "unprognostic (2.50e-1)" "unprognostic (6.89e-4)" "unprognostic (4.11e-1)" "unprognostic (3.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.66e-6)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (8.94e-2)" "unprognostic (3.08e-1)" 5.9 3.1 5.3 4.2 5.8 3.5 8.3 3.9 5.4 21.5 5.8 2.8 1.6 7.3 2.6 6.5 7.5 7.3 4.0 3.9 7.3 4.8 2.1 6.0 5.6 8.4 6.5 11.9 3.4 9.1 2.4 3.1 6.9 4.8 3.6 10.5 4.5 4.6 1.6 5.7 2.6 7.6 6.3 4.3 4.4 10.3 6.1 4.3 7.2 5.4 6.8 5.2 5.5 4.6 4.3 2.6 2.9 4.8 8.5 22.3 1.7 4.4 5.6 3.2 4.6 1.3 2.8 1.2 4.5 27.0 6.1 4.6 10.3 5.0 5.7 1.2 4.8 2.3 3.3 1.1 8.3 3.0 5.0 5.3 5.3 4.3 34.2 5.7 4.8 3.5 1.2 3.0 15.4 2.3 2.5 2.3 1.2 0.8 18.6 1.4 2.1 2.2 4.9 3.1 2.6 5.3 6.1 2.2 3.8 3.4 3.1 3.0 6.5 3.8 2.5 20.4 2.5 2.2 2.4 1.4 4.2 6.0 7.2 4.4 3.9 0.4 16.7 4.8 14.5 4.6 16.6 15.5 4.7 5.0 12.1 10.4 2.2 11.0 3.1 0.7 14.3 10.0 5.3 5.8 3.9 5.4 3.9 7.3 8.4 6.5 6.9 6.3 6.1 4.6 9.6 0.0 7.9 14.0 19.1 4.2 6.3 3.4 6.2 9.5 7.3 5.2 2.4 0.0 7.1 1.8 16.7 1.8 37.9 1.6 1.9 4.4 1.1 9.6 7.1 13.9 3.0 11.2 11.5 4.0 1.8 10.5 11.7 6.2 2.5 6.7 6.1 2.7 1.9 1.7 11.8 2.2 8.2 9.3 11.1 1.8 7.8 10.8 3.6 19.7 9.1 35.9 32.0 8.5 10.6 4.1 1.6 5.3 18.7 11.5 1.2 2.9 12.2 7.8 6.6 8.1 8.3 4.2 5.6 5.5 4.5 1.9 30.0 12.1 1.5 7.9 CACNB3 CACNLB3 ENSG00000167535 "Calcium voltage-gated channel auxiliary subunit beta 3" P54284 12 48813794-48828941 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.9;U-937: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059515 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA059515: AB_2684047" "unprognostic (1.77e-2)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (2.12e-2)" "unprognostic (8.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.27e-2)" "unprognostic (2.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.04e-1)" "unprognostic (5.44e-3)" "unprognostic (6.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.78e-3)" 10.1 3.9 67.9 2.8 69.9 1.3 9.0 56.8 84.2 33.7 44.1 18.1 4.1 31.1 8.5 21.5 19.6 7.2 8.4 72.6 56.7 12.4 1.9 11.8 1.8 50.2 56.2 43.7 4.5 5.1 12.3 5.8 53.4 13.7 8.2 4.7 13.0 9.1 2.8 11.5 10.8 23.1 49.9 6.1 9.2 8.6 59.6 7.6 9.6 5.9 4.1 14.5 20.2 58.7 17.3 13.2 21.1 46.1 26.8 18.0 12.9 16.8 39.4 25.6 14.5 4.5 13.4 2.2 21.5 30.7 4.4 17.2 21.6 19.5 10.1 18.4 5.9 8.5 11.7 0.6 11.0 1.7 9.1 11.7 10.6 10.2 5.5 75.9 31.1 18.6 1.2 7.2 16.9 42.6 22.1 2.2 13.3 18.1 10.9 24.0 5.0 6.6 19.9 31.6 32.9 31.8 5.5 37.1 12.0 18.6 25.2 7.7 27.3 15.5 21.7 7.7 9.5 7.1 3.5 0.7 12.9 109.9 5.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.6 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.2 67.9 69.9 56.8 84.2 72.6 56.7 50.2 56.2 53.4 49.9 59.6 58.7 5.6 3.2 4.3 1.0 0.5 2.9 3.2 5.9 4.0 3.2 8.7 5.7 2.8 1.5 5.1 1.8 4.2 0.8 2.1 12.6 1.9 9.5 1.0 10.0 22.0 5.9 10.2 0.8 15.1 4.3 10.4 7.9 6.1 7.1 1.3 12.0 3.6 0.2 1.6 0.0 4.5 9.5 16.2 0.6 2.9 2.7 13.4 2.4 1.8 3.7 3.7 1.0 2.1 2.0 1.1 10.4 4.6 10.9 1.3 2.9 8.7 0.7 9.4 1.0 0.0 1.5 12.2 1.6 8.1 9.6 5.1 1.1 3.5 6.1 14.4 1.9 CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.4;skin 1: 7.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 495.6;Inhibitory neurons: 470.7;Microglial cells: 136.8;Oligodendrocyte precursor cells: 155.3" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Cell line enhanced" "Detected in some" "Hep G2: 4.1;HMC-1: 20.2;U-937: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 6: Brain - Smell perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA015601: AB_1845873" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.49e-2)" "unprognostic (3.70e-1)" "unprognostic (9.42e-4)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.55e-2)" "unprognostic (7.26e-3)" "unprognostic (3.93e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" 0.7 0.7 4.6 0.4 12.0 0.7 1.5 15.2 16.4 0.4 1.3 0.3 0.4 0.4 0.6 1.4 0.3 0.9 0.3 6.2 2.3 1.4 0.1 2.0 0.3 0.2 5.6 0.3 0.4 0.4 1.8 0.9 0.3 2.0 0.5 1.8 1.7 1.9 0.1 7.3 0.3 0.5 0.3 0.4 0.6 2.3 6.8 1.1 1.4 0.2 1.0 2.0 0.5 6.8 0.0 0.0 0.7 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.9 0.0 1.9 0.0 0.1 0.3 3.2 0.0 0.2 4.1 0.0 0.2 20.2 0.2 0.1 0.4 0.0 1.7 0.0 0.8 0.0 0.5 0.1 0.0 0.2 0.3 0.5 0.1 0.6 2.0 0.2 0.6 1.1 0.5 1.3 0.7 0.0 0.0 0.0 0.1 3.3 0.8 0.0 1.8 2.0 0.6 0.4 0.3 0.0 0.0 0.4 5.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.1 4.6 12.0 15.2 16.4 6.2 2.3 0.2 5.6 0.3 0.3 6.8 6.8 1.1 12.8 53.3 80.6 0.8 12.4 16.3 3.5 30.7 9.9 6.8 7.2 1.3 0.0 3.8 3.7 4.2 0.1 0.3 0.3 3.9 0.5 0.9 3.0 3.0 1.3 0.0 0.0 495.6 1.5 0.0 7.9 1.1 5.4 0.0 84.1 0.7 0.0 3.4 20.2 470.7 0.0 0.0 1.2 7.5 2.1 3.4 2.4 1.8 136.8 1.2 2.3 1.0 155.3 31.2 1.0 0.1 4.5 2.0 29.0 0.1 0.9 1.2 3.4 0.0 0.6 1.2 0.7 4.1 3.2 8.2 0.0 1.1 6.6 0.1 16.3 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.3" "Cell type enhanced" "Detected in many" "Astrocytes: 410.7;Cytotrophoblasts: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 133.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 154.8;SK-BR-3: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 22.0 14.0 86.1 17.0 92.6 34.5 15.2 79.9 137.8 24.1 44.1 101.1 34.2 45.2 14.5 34.7 30.6 17.8 11.8 91.3 79.0 19.3 14.5 18.8 16.2 96.1 96.5 12.7 10.3 12.3 14.1 27.3 94.1 31.1 26.1 42.4 22.9 49.6 154.3 17.3 41.5 43.9 91.4 24.9 30.4 6.5 102.5 15.7 13.6 84.8 14.9 58.4 25.8 91.9 35.7 24.6 22.5 43.9 16.7 26.1 26.3 25.8 41.0 31.9 26.1 39.8 37.2 27.4 25.7 32.4 12.4 54.9 17.5 20.5 25.3 24.0 22.2 18.2 20.4 17.8 8.1 24.7 29.1 14.4 17.7 32.5 22.1 50.4 28.3 32.5 19.5 37.9 19.0 25.2 41.7 37.5 16.5 21.3 154.8 36.5 25.3 13.7 17.2 51.5 11.5 28.4 15.0 177.4 11.9 16.5 33.2 15.0 36.7 24.9 40.0 13.4 33.3 11.9 14.9 24.8 26.5 69.2 8.8 31.0 17.9 133.9 23.1 7.9 28.5 13.9 26.3 25.0 23.0 12.7 24.5 24.1 115.8 34.0 15.1 7.9 27.7 17.5 86.1 92.6 79.9 137.8 91.3 79.0 96.1 96.5 94.1 91.4 102.5 91.9 19.3 16.0 11.7 410.7 22.2 9.4 8.7 9.2 14.2 63.3 14.8 16.3 6.7 12.8 15.5 7.3 100.1 163.6 21.3 46.2 13.7 13.3 2.0 6.3 6.4 20.2 23.9 13.3 107.9 19.6 45.2 12.0 14.8 7.5 16.5 20.2 16.4 9.6 27.2 26.9 89.7 24.8 10.2 18.9 16.3 3.1 12.8 15.8 12.4 43.1 18.3 17.7 26.8 61.9 16.9 22.0 65.5 18.8 13.6 8.2 77.1 26.9 10.4 77.0 46.0 11.2 50.8 0.8 13.5 26.5 12.6 81.1 30.3 5.2 32.1 13.7 CAMKK2 "CAMKK, CAMKKB, KIAA0787, MGC15254" ENSG00000110931 "Calcium/calmodulin dependent protein kinase kinase 2" Q96RR4 12 121237675-121298308 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.8;Horizontal cells: 62.2;Late spermatids: 89.6" "Cancer enriched" "Detected in all" 5 "prostate cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 32.7;eosinophil: 62.1;intermediate monocyte: 42.3;myeloid DC: 15.9;neutrophil: 39.2;non-classical monocyte: 39.5" "Group enriched" "Detected in all" 5 "dendritic cells: 15.9;granulocytes: 62.1;monocytes: 42.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017389, HPA063713" Approved Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA017389: AB_1845956, HPA063713: " "unprognostic (5.08e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.88e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-3)" "unprognostic (2.80e-2)" "unprognostic (1.93e-1)" "unprognostic (7.76e-2)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (4.13e-1)" "unprognostic (3.34e-2)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" 26.0 16.7 39.6 17.0 56.2 30.8 22.7 135.4 65.5 22.3 14.3 22.8 25.7 22.9 10.8 17.5 27.5 12.9 17.8 44.8 24.8 16.7 30.9 23.6 15.3 20.8 20.1 27.4 16.8 12.4 11.8 15.3 24.9 29.5 19.4 7.1 18.6 23.8 11.5 18.3 26.6 20.7 18.3 39.6 24.0 7.0 23.6 13.4 17.1 11.2 15.6 25.9 21.1 42.7 27.9 20.5 16.3 30.9 46.7 43.0 22.8 22.0 23.8 19.0 17.3 21.4 12.1 43.0 18.1 48.1 14.1 22.7 20.0 25.8 15.1 29.3 35.9 22.0 14.4 21.3 31.1 50.0 20.0 28.2 37.2 18.0 41.4 26.0 45.0 33.5 25.2 23.6 18.4 27.2 55.8 40.6 11.7 24.9 22.7 35.3 18.4 37.7 18.8 32.1 60.2 22.4 31.5 16.5 19.1 12.9 39.7 62.0 32.2 14.8 11.8 13.1 13.0 84.8 55.6 32.7 27.7 34.4 16.0 2.0 32.7 62.1 4.7 42.3 4.6 4.8 3.5 4.2 15.9 2.8 3.2 3.8 39.2 8.6 39.5 3.6 3.3 15.8 39.6 56.2 135.4 65.5 44.8 24.8 20.8 20.1 24.9 18.3 23.6 42.7 25.4 9.6 5.6 9.8 5.7 7.9 6.0 8.1 8.0 22.2 11.6 10.5 8.2 12.8 8.3 9.2 2.1 9.2 10.6 18.2 3.9 9.6 16.0 6.5 19.6 21.9 34.3 12.0 64.8 10.4 8.2 18.0 13.3 10.9 6.3 23.3 15.0 19.7 7.9 62.2 21.4 16.2 8.2 14.8 15.6 89.6 20.5 16.6 8.8 12.2 36.3 5.4 12.3 10.1 19.3 8.5 10.9 31.6 11.9 16.5 26.6 9.6 7.2 7.0 19.7 7.7 20.6 0.8 2.9 13.3 6.0 3.4 7.6 32.7 17.6 6.3 CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 60.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.3;Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 89.8;Paneth cells: 72.6;Proximal enterocytes: 75.6;Undifferentiated cells: 69.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Cell line enhanced" "Detected in many" "OE19: 106.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" 6.7 12.2 8.5 10.9 7.9 2.7 4.9 6.4 8.6 13.5 3.5 60.5 60.7 10.0 5.7 31.6 10.8 36.3 7.2 8.5 8.7 15.1 52.1 4.8 1.9 11.7 8.2 13.2 5.6 1.0 5.1 2.8 12.5 16.0 49.9 3.8 7.7 8.9 1.6 3.1 52.4 11.3 9.9 3.5 47.9 21.5 7.9 2.8 4.7 1.7 2.7 15.4 10.5 8.1 0.8 12.5 8.6 7.8 32.0 30.4 0.7 11.8 22.9 13.4 10.0 6.9 3.6 0.4 7.7 24.5 14.4 0.5 3.8 1.0 6.4 0.5 0.8 2.1 0.5 0.9 7.9 0.2 0.4 16.1 1.4 22.6 5.2 18.8 14.4 5.1 0.2 0.0 26.9 19.9 1.8 0.3 6.6 106.6 9.3 2.0 27.0 0.4 4.6 16.4 0.5 13.5 1.0 2.7 5.9 5.7 1.7 0.1 23.9 25.4 12.3 34.8 1.3 0.8 1.7 0.1 13.1 0.3 5.7 0.0 0.2 0.0 1.3 0.3 0.1 0.0 0.1 0.5 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.1 0.0 0.7 8.5 7.9 6.4 8.6 8.5 8.7 11.7 8.2 12.5 9.9 7.9 8.1 1.6 0.0 0.5 4.2 1.0 1.7 0.3 2.2 0.0 3.1 0.5 1.8 1.7 24.3 10.3 23.9 0.0 0.1 3.4 170.3 1.9 10.3 1.1 1.9 5.9 2.4 22.3 5.7 4.6 32.7 0.4 7.6 80.0 3.5 0.0 10.2 2.9 40.4 0.9 1.7 6.7 89.8 10.2 1.6 1.8 1.3 12.5 1.2 7.2 1.0 0.3 5.8 5.2 11.6 0.7 22.4 72.6 4.5 0.9 2.0 75.6 9.9 11.1 2.1 0.0 8.3 4.1 0.5 2.3 2.5 0.9 0.0 1.5 5.3 69.2 2.4 CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.8;brain: 19.3;epididymis: 8.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 8.9;Excitatory neurons: 26.9;Inhibitory neurons: 31.6;Peritubular cells: 38.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 50 "SH-SY5Y: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" NA NA 10000000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" 1.6 17.8 14.6 0.1 3.4 0.0 1.4 0.0 9.4 1.9 0.0 0.0 0.0 0.7 8.8 0.1 3.8 0.5 0.0 14.4 5.8 0.6 0.9 0.7 0.0 0.7 19.3 2.0 0.7 0.3 0.1 0.2 2.4 0.1 0.0 0.3 0.1 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.3 2.0 12.2 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 3.4 0.0 9.4 14.4 5.8 0.7 19.3 2.4 0.0 12.2 0.2 0.1 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.2 8.9 0.0 26.9 0.0 0.0 5.2 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.7 31.6 0.0 0.0 0.0 0.0 1.0 2.1 0.2 0.0 1.9 0.0 0.2 0.0 1.0 2.0 0.0 0.0 38.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 CC2D2A "JBTS9, KIAA1345, MKS6" ENSG00000048342 "Coiled-coil and C2 domain containing 2A" Q9P2K1 4 15469865-15601552 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 84.7" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044124 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA044124: AB_10969197" "unprognostic (1.88e-1)" "unprognostic (2.05e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-3)" "unprognostic (2.13e-2)" "unprognostic (1.10e-1)" "unprognostic (8.63e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-2)" "unprognostic (2.23e-2)" "unprognostic (7.33e-2)" "prognostic favorable (3.42e-9)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (2.18e-2)" 8.3 9.3 13.5 2.7 13.0 2.7 8.8 14.2 16.5 14.2 22.1 17.3 4.9 12.8 11.1 8.3 34.2 12.4 7.4 13.2 13.5 23.6 2.9 10.7 2.0 13.7 14.6 11.7 5.1 10.0 12.7 8.5 12.6 10.0 5.9 84.7 3.3 12.5 2.5 2.3 5.0 15.4 12.0 3.3 8.2 4.9 14.7 1.2 8.2 11.1 1.4 9.3 6.4 12.7 5.4 11.3 15.6 7.0 18.4 34.4 3.8 6.8 11.5 12.7 15.5 5.1 13.2 0.5 7.3 13.1 27.7 3.4 13.1 8.7 15.9 0.0 7.3 5.5 10.1 7.1 13.5 0.5 0.1 25.0 22.8 20.7 15.5 23.3 5.9 0.2 14.7 0.4 24.4 3.9 0.2 0.9 25.9 0.2 23.3 3.5 4.9 1.1 32.1 2.6 9.7 11.1 4.3 3.1 32.2 14.6 4.9 1.3 2.2 20.2 12.0 8.6 14.4 0.4 0.5 0.3 24.3 0.3 13.1 1.9 2.4 0.2 0.4 1.6 0.6 0.3 0.3 0.1 3.8 0.3 0.2 0.4 4.8 0.9 0.8 0.2 0.9 0.6 13.5 13.0 14.2 16.5 13.2 13.5 13.7 14.6 12.6 12.0 14.7 12.7 8.4 12.8 14.6 39.8 0.7 2.2 5.6 5.7 14.2 15.1 6.5 9.0 22.9 10.0 23.5 25.8 569.2 10.2 0.3 0.8 33.2 6.6 12.0 96.8 14.0 7.0 6.0 2.7 20.9 0.9 3.1 18.7 4.1 9.0 0.0 15.2 8.9 1.6 5.0 8.4 43.4 0.9 8.2 5.7 4.6 6.7 9.3 4.4 12.4 16.9 1.2 18.4 0.0 62.8 19.5 1.0 0.5 16.6 1.3 4.4 2.1 57.1 128.4 136.4 6.6 14.7 17.7 2.6 0.7 6.4 1.3 1.5 1.9 12.9 2.9 4.0 CCDC102A MGC10992 ENSG00000135736 "Coiled-coil domain containing 102A" Q96A19 16 57512181-57536571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 16.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040598, HPA040958" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA040598: AB_10794035, HPA040958: AB_10794156" "unprognostic (3.46e-2)" "unprognostic (3.04e-2)" "unprognostic (1.88e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (2.42e-1)" "unprognostic (4.01e-3)" "unprognostic (7.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.38e-1)" "unprognostic (5.24e-3)" "unprognostic (8.40e-3)" "unprognostic (4.08e-1)" "unprognostic (2.75e-1)" "unprognostic (2.37e-1)" "unprognostic (8.42e-3)" 5.0 3.7 1.8 2.7 1.6 0.5 4.8 1.7 2.4 10.9 4.1 11.1 2.3 11.0 1.1 3.5 8.8 1.5 6.8 1.6 1.7 5.2 1.5 4.5 3.0 2.5 2.4 8.0 3.3 1.5 2.3 2.5 2.0 8.4 0.5 0.1 4.0 3.8 1.6 4.9 4.7 2.4 2.1 5.1 4.8 3.0 2.4 1.6 5.8 0.5 1.7 11.9 8.2 1.5 6.6 7.9 3.0 4.3 1.0 1.4 6.2 4.2 2.3 2.4 1.2 3.2 7.5 6.0 16.4 1.3 3.2 4.8 1.5 2.2 0.9 4.9 6.8 0.8 3.8 1.3 3.7 0.4 7.7 3.5 1.4 2.0 0.5 5.2 1.9 2.1 4.6 0.0 0.8 2.7 5.4 5.3 7.1 0.7 14.6 4.8 3.4 2.4 3.0 1.0 0.5 7.8 6.6 2.1 3.2 1.1 4.5 2.9 5.2 4.4 14.5 0.4 3.8 6.9 2.7 2.2 2.5 2.1 7.4 0.0 0.0 0.0 1.1 0.0 0.9 0.9 0.2 1.2 0.0 0.5 0.5 0.8 0.1 0.6 0.0 0.3 0.0 0.2 1.8 1.6 1.7 2.4 1.6 1.7 2.5 2.4 2.0 2.1 2.4 1.5 8.8 0.0 3.0 0.7 8.2 12.9 8.0 2.4 14.8 0.0 4.9 10.3 3.1 5.7 2.2 7.3 0.0 1.6 16.3 0.5 9.8 1.9 0.6 6.0 8.5 10.6 0.0 3.4 0.0 0.9 1.1 13.2 2.0 1.8 0.0 14.6 7.1 0.9 0.3 0.0 0.1 1.0 0.0 0.6 2.8 1.3 19.6 1.5 1.8 1.0 0.5 3.5 18.6 0.0 0.0 0.9 0.1 34.6 18.8 10.6 1.1 10.5 3.1 0.2 19.7 10.8 11.8 2.8 8.9 2.3 5.7 0.3 10.5 3.3 1.0 3.2 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 450.8;Fibroblasts: 921.6;Late spermatids: 353.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 521.4;fHDF/TERT166: 1281.3;hTERT-RPE1: 2404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" NA NA 510000 "Cluster 41: Basophils - Cellular respiration" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" 244.9 15.0 6.4 83.5 6.9 1.1 218.3 9.6 8.6 305.3 24.4 74.5 8.7 276.5 76.8 92.4 82.2 234.0 218.8 6.8 10.2 17.7 6.6 74.0 18.5 12.2 11.4 62.2 28.7 12.4 10.8 26.0 9.3 67.8 73.4 9.4 34.7 78.7 13.4 79.1 25.1 360.3 11.1 34.8 47.5 42.7 9.2 17.1 87.5 34.9 30.8 194.4 131.8 13.5 26.1 11.0 127.6 5.8 521.4 411.2 6.9 359.0 108.5 118.6 171.8 2.9 2.1 1.2 13.5 1281.3 11.4 33.5 5.3 4.8 123.7 24.3 1.2 0.7 27.7 0.7 109.5 1.0 0.5 409.7 14.4 174.9 11.0 2404.9 27.8 0.6 0.4 1.0 352.7 0.5 0.3 0.7 31.6 0.7 4.2 0.3 14.0 0.6 3.3 0.5 0.4 2.5 53.5 2.3 1.8 23.0 2.1 1.0 141.7 345.6 56.6 66.6 160.1 1.6 0.8 1.2 102.4 0.7 56.8 0.9 0.3 0.2 0.3 0.1 0.3 0.4 0.3 0.3 0.1 0.6 0.4 0.4 0.3 0.3 0.2 0.7 0.2 0.0 6.4 6.9 9.6 8.6 6.8 10.2 12.2 11.4 9.3 11.1 9.2 13.5 104.5 6.4 15.9 13.1 1.5 60.9 4.2 44.7 26.7 1.1 5.9 59.7 22.5 10.0 62.7 5.5 0.0 57.9 1.0 0.3 1.9 23.7 450.8 95.4 93.2 43.9 0.0 0.0 1.0 1.2 101.5 921.6 16.8 18.4 1.3 44.3 53.6 0.9 9.4 0.0 0.3 0.8 30.5 2.2 121.5 353.6 77.0 9.7 144.1 3.7 2.0 101.4 0.0 0.0 0.0 13.5 0.0 34.6 5.8 3.6 0.0 0.1 112.4 2.5 19.7 177.7 198.4 6.9 4.9 11.9 51.7 27.9 9.0 23.0 0.1 1.9 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CDH11 "CAD11, OB" ENSG00000140937 "Cadherin 11" P55287 16 64943753-65126112 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 178.2;placenta: 122.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Endometrial stromal cells: 125.0;Excitatory neurons: 122.2;Fibroblasts: 102.2;Microglial cells: 145.2;Oligodendrocyte precursor cells: 158.3;Oligodendrocytes: 106.3;Theca cells: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 246.5;BJ hTERT+: 139.3;fHDF/TERT166: 332.3;HSkMC: 217.4;PC-3: 291.2;U-2197: 194.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013072 Enhanced NA Yes 4800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB013072: AB_2533068" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (1.02e-1)" "unprognostic (6.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.09e-1)" "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (6.75e-2)" "prognostic unfavorable (2.48e-9)" "unprognostic (1.43e-3)" "unprognostic (3.20e-2)" "unprognostic (1.26e-1)" "unprognostic (5.07e-3)" 15.1 8.6 12.4 25.7 27.9 0.3 10.7 10.8 15.8 57.7 13.8 11.4 7.0 52.8 9.5 7.4 12.5 58.6 10.2 19.2 21.4 10.2 1.8 45.6 17.5 17.1 24.1 178.2 3.4 2.6 10.4 122.2 17.3 20.0 12.2 14.0 12.7 24.3 2.6 10.9 8.9 54.3 21.1 89.3 11.8 8.0 19.3 3.7 8.1 3.1 13.0 47.6 13.6 21.4 0.2 0.0 51.4 0.1 35.7 77.5 0.3 246.5 139.3 61.0 34.5 4.6 0.2 0.0 0.0 332.3 0.0 0.1 0.1 1.7 43.4 0.0 2.1 0.0 1.4 0.0 29.7 0.0 14.4 217.4 0.1 74.7 14.9 0.0 17.4 0.0 0.0 0.0 33.1 0.3 0.1 0.3 19.2 37.4 291.2 0.8 38.0 0.0 0.0 0.0 0.8 36.0 0.1 0.3 0.2 64.5 0.3 0.1 0.0 124.4 17.2 194.0 70.1 0.0 0.0 0.1 21.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 27.9 10.8 15.8 19.2 21.4 17.1 24.1 17.3 21.1 19.3 21.4 11.4 3.2 0.0 93.0 0.1 3.8 1.0 7.9 0.0 19.9 1.0 7.4 3.1 1.5 3.3 0.0 0.0 2.6 0.2 0.1 0.0 0.1 2.7 3.9 125.0 17.8 0.0 2.7 122.2 0.0 2.3 102.2 0.5 2.7 0.0 60.0 68.9 0.0 4.7 0.0 67.6 0.6 0.0 0.6 6.9 4.2 52.5 0.9 5.4 145.2 0.0 41.9 0.0 158.3 106.3 0.8 0.0 77.5 0.0 1.6 0.0 1.4 0.4 2.1 26.3 12.8 38.0 1.7 1.1 0.5 3.1 5.6 1.1 160.2 0.3 0.5 CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Excitatory neurons: 67.1;Oligodendrocyte precursor cells: 60.8;Pancreatic endocrine cells: 63.8;Proximal tubular cells: 171.1;Sertoli cells: 46.0;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 477.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" 5.0 1.1 3.2 1.4 9.3 0.2 2.6 2.2 3.7 4.3 0.5 1.3 1.3 2.3 1.8 2.4 6.8 9.2 2.0 2.2 7.4 14.8 0.7 4.5 0.6 4.9 9.5 0.7 0.7 1.1 1.0 3.6 6.0 1.1 0.9 1.5 0.7 1.8 1.2 1.0 1.2 2.6 3.2 0.8 1.0 0.3 9.8 0.4 2.3 1.6 0.7 2.3 1.9 3.9 0.1 1.9 62.2 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.2 0.0 0.1 477.1 0.3 0.0 0.0 49.6 0.1 0.0 0.6 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 17.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 9.4 0.0 0.2 0.0 10.9 0.1 14.0 0.0 1.8 0.0 0.0 0.1 0.2 19.3 0.1 0.2 0.0 0.1 1.8 5.9 1.5 0.1 0.4 1.1 0.1 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 9.3 2.2 3.7 2.2 7.4 4.9 9.5 6.0 3.2 9.8 3.9 5.7 0.0 0.5 7.2 2.4 0.9 0.1 36.5 0.0 10.8 0.1 0.4 3.1 48.6 7.0 11.0 0.0 0.0 0.0 0.0 27.4 37.2 0.2 2.9 0.6 5.3 0.0 0.0 67.1 3.0 0.0 2.9 0.0 2.9 0.0 4.1 0.0 0.1 0.1 0.0 33.6 0.0 0.0 0.0 2.5 0.1 0.3 1.3 0.0 39.4 1.0 0.3 0.0 60.8 5.5 63.8 0.0 0.4 0.0 1.2 0.0 171.1 1.1 0.8 46.0 0.6 69.5 0.0 0.4 0.1 1.0 0.0 1.8 0.2 0.0 0.1 CDHR4 "CDH29, VLLR9392" ENSG00000187492 "Cadherin related family member 4" A6H8M9 3 49790732-49799873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 59.4" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 74.2;Respiratory ciliated cells: 160.4" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 6.8" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.3;HeLa: 1.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.2" HPA076277 Enhanced "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA076277: AB_2732306" "unprognostic (1.50e-4)" "unprognostic (4.87e-2)" "unprognostic (6.00e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (2.45e-3)" "unprognostic (6.35e-7)" "unprognostic (1.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.12e-1)" "unprognostic (9.61e-2)" "unprognostic (2.35e-1)" "unprognostic (9.07e-11)" "unprognostic (2.65e-1)" "unprognostic (3.70e-2)" "unprognostic (1.13e-2)" "unprognostic (2.37e-1)" 0.5 0.1 0.6 0.1 0.6 0.2 0.2 0.4 0.3 5.5 1.0 0.5 0.1 1.7 0.4 0.1 59.4 0.1 0.2 0.6 0.7 0.2 0.1 7.4 0.0 2.7 6.1 0.2 0.0 0.0 0.1 0.1 3.4 0.3 0.1 0.0 0.2 0.2 0.2 1.3 0.1 0.2 1.2 0.0 0.1 7.5 0.8 0.0 0.2 0.0 0.0 0.2 0.3 1.0 0.1 0.5 0.1 0.0 0.1 1.3 0.1 0.1 0.0 0.2 0.3 0.0 0.8 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.5 0.3 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.2 0.7 0.0 0.6 0.4 0.0 1.9 2.0 0.2 0.1 0.7 0.1 0.2 0.1 0.1 0.7 0.4 0.1 0.1 1.0 0.5 0.1 0.2 0.1 3.9 0.6 0.6 0.4 0.3 0.6 0.7 2.7 6.1 3.4 1.2 0.8 1.0 0.2 0.0 3.4 0.0 0.0 0.1 0.1 4.3 0.0 0.0 0.1 0.1 0.4 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 74.2 0.9 0.5 0.0 0.0 0.1 0.2 0.1 0.9 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 20.3 0.0 0.0 4.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 160.4 0.0 0.0 0.2 1.7 4.8 0.8 0.0 0.0 0.0 0.2 0.1 0.2 0.1 CDIN1 "C15orf41, FLJ22851, HH114, MGC11326" ENSG00000186073 "CDAN1 interacting nuclease 1" Q9Y2V0 15 36579626-36810248 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 78.6;tongue: 34.5" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 97.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061023 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA061023: AB_2684417" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (2.93e-3)" "unprognostic (2.27e-2)" "unprognostic (2.37e-2)" "unprognostic (2.02e-2)" "unprognostic (3.40e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-3)" "unprognostic (9.14e-2)" "unprognostic (3.74e-6)" "unprognostic (1.22e-2)" "unprognostic (4.54e-2)" "unprognostic (1.62e-4)" "unprognostic (1.58e-1)" 2.8 5.1 2.9 2.4 7.9 0.7 2.9 4.3 4.1 5.9 1.6 5.6 6.7 6.8 1.8 9.4 4.1 4.0 78.6 2.5 3.5 2.8 3.7 2.5 2.4 3.9 3.4 4.3 2.2 2.4 2.3 2.1 4.3 6.0 3.2 9.6 5.0 6.6 12.0 5.6 3.3 9.5 2.9 2.2 3.3 7.1 3.4 4.2 2.5 34.5 3.6 9.5 8.3 4.9 19.0 10.0 12.4 4.7 13.5 15.6 5.1 8.9 4.5 11.1 9.1 13.9 7.4 3.0 8.8 22.1 8.1 33.8 13.0 7.7 12.7 1.5 9.1 9.9 9.0 10.3 11.8 8.4 7.1 12.0 8.3 9.5 5.2 8.5 10.7 9.6 12.9 3.1 15.4 8.6 2.6 4.9 6.8 8.6 5.1 7.9 3.5 2.0 7.4 25.8 7.1 4.4 5.7 5.5 4.8 9.0 5.5 13.1 7.6 10.8 5.9 7.3 2.5 7.2 11.2 13.7 13.7 15.0 10.2 0.0 0.5 0.3 2.5 1.3 2.2 2.1 1.9 2.4 1.4 2.2 2.3 1.9 0.0 3.3 0.4 1.1 5.1 1.1 2.9 7.9 4.3 4.1 2.5 3.5 3.9 3.4 4.3 2.9 3.4 4.9 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.6 0.0 0.0 0.0 0.0 8.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 6.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 10.8 0.2 0.0 0.0 0.0 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900" "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favorable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 53.4 44.7 53.6 40.1 70.6 68.1 50.2 73.4 81.3 55.3 43.1 43.9 44.5 41.0 24.5 29.1 47.3 24.6 32.9 47.9 58.9 30.2 35.2 38.9 55.3 58.6 58.3 66.1 23.9 34.4 24.4 41.0 61.2 35.9 32.5 55.3 36.3 33.4 81.4 45.4 40.7 24.8 55.1 55.1 30.0 25.8 58.3 71.8 33.7 63.4 39.9 32.0 44.5 91.2 37.1 16.6 94.5 16.6 32.0 18.0 46.1 31.5 53.8 46.0 56.4 47.7 40.4 0.3 12.5 19.6 16.6 34.2 44.9 16.7 41.1 62.4 31.5 28.8 46.5 53.2 42.5 24.5 18.6 19.8 35.3 15.2 44.0 107.8 27.8 54.5 31.5 101.6 16.6 45.9 32.7 35.3 38.0 32.1 16.8 25.2 30.9 63.1 22.5 38.6 35.6 58.4 48.9 34.8 65.8 33.7 18.6 54.6 19.1 22.6 34.9 20.7 33.3 86.1 59.4 33.2 28.2 36.6 22.5 6.2 3.8 8.6 5.9 3.5 6.1 6.8 7.7 7.2 3.6 5.0 8.0 6.1 20.9 7.3 5.5 3.9 12.3 4.0 53.6 70.6 73.4 81.3 47.9 58.9 58.6 58.3 61.2 55.1 58.3 91.2 64.2 44.8 29.3 6.2 126.2 52.6 20.7 21.0 115.5 45.6 39.5 30.1 39.1 21.5 27.1 9.2 27.1 42.9 92.5 32.3 15.6 10.8 70.0 31.2 35.8 51.1 45.7 70.5 8.1 9.3 47.6 39.3 25.5 34.3 31.0 21.3 47.2 30.7 26.8 10.1 13.4 41.4 24.4 55.3 66.0 67.7 55.9 65.1 74.7 23.4 31.6 182.9 60.8 6.0 29.5 10.1 21.3 26.7 121.2 30.3 33.4 16.9 36.4 29.4 92.1 20.2 53.5 7.7 10.8 102.3 52.6 39.0 166.1 20.9 41.9 22.7 CDKN1C "BWCR, BWS, KIP2, P57" ENSG00000129757 "Cyclin dependent kinase inhibitor 1C" P49918 11 2883213-2885775 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 206.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 575.3;Extravillous trophoblasts: 1531.7;Syncytiotrophoblasts: 2241.2;Theca cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 155.1;non-classical monocyte: 376.4" "Lineage enriched" "Detected in many" 14 "monocytes: 376.4" "Cell line enhanced" "Detected in many" "EFO-21: 12.0;HeLa: 12.8;RPMI-8226: 18.7;SH-SY5Y: 33.0;SiHa: 25.2;SK-MEL-30: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002924 Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Nuclear bodies" Cytosol "HPA002924: AB_1079548" "unprognostic (5.49e-3)" "unprognostic (2.62e-1)" "unprognostic (9.82e-3)" "unprognostic (5.79e-3)" "unprognostic (4.15e-1)" "unprognostic (2.84e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-1)" "unprognostic (3.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.95e-1)" "unprognostic (3.39e-2)" "unprognostic (2.15e-1)" "unprognostic (3.31e-2)" "unprognostic (8.53e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" 127.4 182.9 8.2 3.3 38.0 1.7 92.5 43.3 18.7 73.7 6.5 48.1 1.4 70.6 0.2 29.9 70.7 0.8 82.6 11.7 18.8 149.5 8.3 34.5 0.2 55.1 33.5 206.4 28.5 0.2 27.8 28.1 45.0 33.1 0.2 0.5 21.7 1.5 60.3 26.6 25.0 0.4 31.8 20.6 54.1 8.6 34.3 0.2 17.0 0.9 0.4 75.0 49.4 95.3 0.1 0.1 1.6 0.0 0.4 0.5 1.8 0.3 0.6 0.3 0.0 3.3 0.4 0.0 12.0 0.2 0.1 0.5 0.3 0.3 0.1 5.6 1.2 0.1 12.8 0.0 3.3 0.0 1.4 2.4 1.6 0.0 0.2 0.1 0.3 0.1 2.7 0.8 0.5 0.1 0.0 6.0 10.6 0.5 4.0 2.2 0.0 18.7 0.7 0.0 3.5 33.0 25.2 0.3 15.2 0.9 0.2 2.8 0.4 0.0 2.2 0.0 0.1 7.3 0.0 0.1 0.0 1.8 6.8 9.1 1.2 0.9 0.4 155.1 1.8 0.0 0.4 0.6 26.9 0.3 1.0 0.3 2.2 0.0 376.4 0.2 0.7 14.7 8.2 38.0 43.3 18.7 11.7 18.8 55.1 33.5 45.0 31.8 34.3 95.3 357.3 3.2 5.8 1.0 11.6 10.7 81.7 4.9 30.7 11.9 81.0 150.5 45.3 61.5 10.8 31.3 6.2 575.3 46.9 20.3 15.6 9.8 176.5 38.8 101.5 100.8 106.5 0.8 0.6 0.6 1531.7 141.0 17.9 56.2 0.0 31.2 74.6 4.0 91.0 8.4 1.2 25.0 12.2 23.5 23.2 276.4 74.3 54.9 35.6 4.7 14.1 68.3 0.0 3.5 65.7 4.3 4.2 44.4 12.9 64.6 4.0 78.5 7.5 27.4 32.9 238.3 71.4 2.1 3.5 17.3 11.8 2241.2 25.1 781.8 15.2 71.8 CDO1 ENSG00000129596 "Cysteine dioxygenase type 1" Q16878 5 115804733-115816659 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 506.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 329.4;Hepatocytes: 149.5;Leydig cells: 91.0;Syncytiotrophoblasts: 481.9;Theca cells: 104.7" "Group enriched" "Detected in many" 6 "glioma: 33.6;liver cancer: 74.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.5" "Lineage enriched" "Detected in single" 15 "T-cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 48.1;ASC diff: 57.9;ASC TERT1: 22.3;GAMG: 17.2;HAP1: 17.1;NTERA-2: 17.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036573, HPA057503" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "HPA036573: AB_10696658, HPA057503: AB_2683451" "unprognostic (2.34e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.32e-1)" "prognostic favorable (1.91e-5)" "unprognostic (1.14e-3)" "unprognostic (2.63e-1)" "unprognostic (7.23e-2)" "unprognostic (9.28e-3)" "unprognostic (6.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.74e-3)" "unprognostic (3.06e-2)" "unprognostic (3.70e-1)" "unprognostic (2.06e-2)" 119.3 18.1 26.1 3.3 28.2 0.2 35.9 24.6 31.2 9.5 109.8 4.8 0.7 8.3 140.3 3.5 13.7 10.5 26.1 28.3 30.7 3.1 506.7 11.7 6.6 23.6 26.2 25.8 14.2 0.7 20.7 35.2 25.6 9.1 1.8 15.9 7.2 72.8 8.5 3.0 4.0 6.2 25.6 3.7 4.1 15.6 26.7 1.3 9.6 19.9 3.1 8.1 5.7 25.6 0.0 0.0 48.1 0.0 57.9 22.3 0.2 1.4 0.4 4.6 4.5 0.0 0.0 0.0 0.0 0.6 17.2 0.1 17.1 0.0 6.6 0.1 8.5 1.7 0.0 1.4 0.2 0.1 0.0 8.5 0.0 0.7 0.0 1.2 6.3 0.0 0.0 0.0 5.5 0.0 1.2 0.2 17.8 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 11.0 0.1 0.0 0.0 4.0 0.0 5.4 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 26.1 28.2 24.6 31.2 28.3 30.7 23.6 26.2 25.6 25.6 26.7 25.6 4.1 0.0 1.3 6.8 0.7 0.8 0.8 0.0 0.6 27.3 1.0 7.1 3.4 0.0 0.0 1.8 6.2 329.4 0.3 0.0 0.0 9.9 6.0 0.3 7.1 3.1 1.8 2.7 12.2 0.2 17.0 27.8 0.0 0.3 0.0 7.5 33.9 149.5 23.4 1.7 16.4 0.0 0.0 5.7 1.6 15.0 91.0 0.6 1.8 1.0 0.6 31.4 0.0 5.5 3.1 0.3 0.0 37.6 0.0 0.9 0.0 2.0 0.0 3.8 13.1 7.3 3.9 1.6 1.4 0.5 1.3 481.9 0.9 104.7 0.0 0.1 CEP57L1 "bA487F23.2, C6orf182, MGC21731" ENSG00000183137 "Centrosomal protein 57 like 1" Q8IYX8 6 109095110-109174418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 50.3;Spermatocytes: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040378 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040378: AB_10794028" "unprognostic (5.93e-3)" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-2)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (4.69e-3)" "unprognostic (3.63e-2)" "unprognostic (7.25e-2)" "unprognostic (1.27e-1)" "unprognostic (2.33e-1)" "unprognostic (9.97e-2)" "unprognostic (2.42e-5)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (8.48e-2)" "unprognostic (1.72e-1)" 10.5 7.6 5.1 7.8 5.9 10.2 10.2 10.8 7.8 8.2 4.6 8.5 8.7 9.3 10.5 6.2 6.0 9.4 7.7 5.8 4.1 8.0 10.0 6.6 8.9 4.9 4.2 6.5 7.5 16.9 5.6 10.1 5.5 6.4 10.9 12.0 5.2 6.3 6.1 6.8 7.8 10.8 3.9 7.7 7.3 26.2 5.5 14.4 8.7 6.6 7.4 6.4 6.5 7.9 17.9 7.9 23.1 22.9 21.2 35.2 18.1 40.3 22.1 35.8 39.8 11.9 15.3 16.0 18.4 20.9 30.8 9.1 16.1 15.4 56.1 20.3 16.1 34.8 18.9 12.3 19.6 28.5 14.5 21.2 11.0 30.3 29.9 19.2 32.4 52.5 63.9 52.5 32.4 11.8 32.0 24.6 7.6 14.7 14.6 25.7 17.4 15.7 17.0 7.4 17.4 14.4 19.8 14.7 12.9 15.0 18.2 43.9 14.7 23.1 13.6 24.4 42.9 15.4 19.1 25.3 21.8 43.1 18.9 15.9 5.2 6.6 4.7 6.1 5.1 3.3 4.8 6.7 5.7 6.3 4.5 6.7 3.6 11.6 9.6 6.0 6.9 4.6 5.1 5.9 10.8 7.8 5.8 4.1 4.9 4.2 5.5 3.9 5.5 7.9 12.9 6.4 5.3 12.4 6.3 3.3 7.6 7.4 7.4 6.6 6.8 7.2 10.3 2.8 6.8 5.5 20.9 9.8 9.7 4.2 7.9 7.0 50.3 12.8 18.5 10.6 5.4 18.1 31.9 5.4 13.2 15.5 8.2 6.9 5.1 20.5 8.2 6.3 10.2 5.0 31.1 3.1 8.2 4.1 6.8 39.3 17.4 7.7 8.8 27.2 7.7 10.4 8.2 26.2 36.1 6.0 4.5 12.4 13.2 4.4 5.7 13.4 9.8 12.3 13.1 21.8 14.1 75.7 13.0 5.8 4.4 8.5 6.7 13.6 6.1 5.0 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CFAP92 "FAP92, FLJ43738, KIAA1257" ENSG00000114656 "Cilia and flagella associated protein 92 (putative)" Q9ULG3 3 128909866-129002690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 22.1" "Group enriched" "Detected in some" 4 "Adipocytes: 1.3;Cardiomyocytes: 1.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "neutrophil: 34.0" "Lineage enriched" "Detected in single" 48 "granulocytes: 34.0" "Cell line enhanced" "Detected in many" "AF22: 7.6;HL-60: 13.5;THP-1: 9.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042811, HPA048445" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042811: AB_2678180, HPA048445: AB_2680397" "unprognostic (4.17e-2)" "unprognostic (5.16e-2)" "unprognostic (2.46e-1)" "unprognostic (2.67e-1)" "unprognostic (9.41e-3)" "unprognostic (2.45e-1)" "unprognostic (6.74e-2)" "unprognostic (4.22e-2)" "unprognostic (6.48e-3)" "unprognostic (7.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.88e-2)" "unprognostic (1.42e-2)" "unprognostic (3.38e-1)" "unprognostic (4.69e-2)" "unprognostic (2.52e-1)" "unprognostic (5.50e-2)" 0.4 0.6 3.1 1.0 2.1 2.1 0.8 3.9 2.2 0.4 4.4 0.7 0.8 0.7 0.5 1.1 3.3 1.4 0.6 3.7 2.5 0.5 0.2 1.1 1.0 3.1 4.7 1.2 0.9 1.7 1.8 1.1 3.2 1.0 0.8 2.7 0.7 0.3 0.7 4.3 0.9 0.2 1.4 1.0 1.1 22.1 3.3 4.2 0.8 0.5 0.3 0.4 0.1 1.3 1.0 1.4 7.6 1.6 0.1 0.2 2.4 0.3 0.3 0.1 0.0 1.2 1.0 1.5 0.3 0.0 0.7 1.1 2.3 0.1 0.0 0.6 1.1 3.3 1.9 1.0 0.0 13.5 0.7 0.0 1.4 0.0 0.1 0.5 0.1 2.9 0.9 1.7 0.2 1.5 1.3 2.5 1.4 2.6 1.4 1.1 0.8 0.9 0.0 1.5 1.5 0.7 0.4 0.5 0.6 1.0 2.6 9.2 0.4 0.8 1.2 0.8 0.5 2.2 2.0 2.5 0.6 5.0 0.6 0.8 0.7 2.9 0.3 0.3 0.2 0.4 0.2 0.2 0.2 0.3 0.3 0.5 34.0 0.3 0.3 0.3 0.2 0.2 3.1 2.1 3.9 2.2 3.7 2.5 3.1 4.7 3.2 1.4 3.3 1.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHODL "C21orf68, FLJ12627, MT75, PRED12" ENSG00000154645 Chondrolectin Q9H9P2 21 17901263-18267373 "Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.5;lymphoid tissue: 14.1;testis: 31.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 38.6;Oligodendrocytes: 50.1;Skeletal myocytes: 28.3;Theca cells: 26.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 1.5" "Lineage enriched" "Detected in single" 7 "T-cells: 1.5" "Cell line enhanced" "Detected in some" "HDLM-2: 1.8;U-266/70: 2.8;U-266/84: 7.2;U-87 MG: 7.8" "Group enriched" "Detected in many" 4 "basal ganglia: 3.9;hypothalamus: 12.3;pons and medulla: 10.9" "Group enriched" "Detected in all" 4 "olfactory bulb: 66.4;spinal cord: 38.6" "HPA017282, HPA057559" Enhanced Approved Centrosome,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 36: Stromal cells - Cell proliferation" Cytosol Centrosome "HPA017282: AB_1846687, HPA057559: " "unprognostic (3.91e-1)" "unprognostic (3.18e-2)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.18e-6)" "unprognostic (6.74e-2)" "unprognostic (6.82e-2)" "unprognostic (1.06e-3)" "unprognostic (6.79e-2)" "unprognostic (8.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-3)" "unprognostic (1.36e-2)" "unprognostic (1.87e-1)" "unprognostic (4.83e-2)" "unprognostic (1.02e-1)" 3.3 2.0 1.6 1.1 1.4 0.0 1.1 0.7 1.6 0.2 0.8 2.8 1.6 0.6 1.1 0.9 0.5 0.8 3.7 1.7 5.4 3.6 0.0 0.3 0.4 11.5 2.6 0.6 0.1 0.3 2.5 1.9 10.8 5.6 3.5 0.6 0.5 1.8 0.6 2.3 1.0 0.3 1.6 14.1 0.7 31.0 10.2 0.3 1.1 1.7 1.2 0.7 1.1 3.8 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 1.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.4 0.1 1.4 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.7 0.6 0.9 0.0 0.1 0.1 0.1 0.1 0.0 0.0 2.8 7.2 0.2 7.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.5 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.3 0.1 1.6 1.4 0.7 1.6 1.7 5.4 11.5 2.6 10.8 1.6 10.2 3.8 1.7 0.0 0.0 5.2 1.0 4.0 0.8 0.8 3.4 1.1 1.0 1.3 0.5 0.0 0.9 0.0 0.0 0.2 0.9 0.0 1.9 0.4 5.0 1.4 38.6 1.5 0.0 0.0 5.5 0.0 0.2 4.6 0.0 0.8 0.0 12.3 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.8 4.0 3.1 0.1 1.8 4.7 0.0 0.4 0.0 12.5 50.1 0.0 0.0 1.9 3.1 0.2 0.0 0.3 0.3 0.1 0.0 28.3 10.5 1.3 1.7 0.5 2.3 0.5 1.3 26.7 0.1 0.3 CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 224.4" "Group enriched" "Detected in many" 4 "Astrocytes: 50.3;Fibroblasts: 83.8;Leydig cells: 41.0;Muller glia cells: 81.6" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "ASC diff: 537.8;ASC TERT1: 724.7;hTERT-RPE1: 341.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" NA NA 610000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" 188.3 7.3 7.1 26.2 14.5 0.9 69.8 8.3 14.1 38.8 6.5 74.8 10.8 148.2 20.2 58.0 53.5 47.9 22.0 9.4 6.2 15.1 1.8 76.3 24.4 4.4 4.5 7.1 12.5 84.9 6.4 21.9 4.0 141.6 35.5 55.6 23.3 224.4 6.1 17.5 22.1 101.3 4.3 16.0 17.9 6.5 5.8 10.9 37.8 34.9 11.7 28.3 20.0 6.3 0.0 0.1 3.3 0.0 537.8 724.7 0.3 7.6 3.3 18.8 16.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.0 0.0 17.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 58.7 0.1 1.6 0.0 341.2 0.0 2.0 0.0 0.0 0.1 0.0 1.0 0.3 21.3 0.0 0.0 0.0 0.0 0.1 3.0 0.0 1.7 5.2 0.0 0.0 0.4 1.4 0.0 0.0 0.0 5.8 4.2 60.4 7.8 0.1 0.1 0.0 5.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 7.1 14.5 8.3 14.1 9.4 6.2 4.4 4.5 4.0 4.3 5.8 6.3 8.4 0.0 2.7 50.3 0.1 4.8 0.0 0.0 0.6 1.5 0.3 0.4 2.3 0.0 1.8 1.8 0.0 0.1 0.1 0.0 0.0 0.3 0.3 0.0 1.0 13.8 0.0 0.0 4.2 0.0 0.1 83.8 2.0 0.2 1.3 0.3 2.2 0.1 0.2 0.0 9.3 0.0 0.0 0.0 8.1 1.4 41.0 1.1 8.8 1.0 0.0 81.6 0.0 13.6 0.2 0.0 0.0 9.1 1.4 0.3 0.0 4.1 1.5 2.9 0.0 2.7 11.2 0.2 8.2 0.3 4.4 0.1 1.0 0.0 0.0 0.1 CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725718 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 132.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Fibroblasts: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.3" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 363.0;HMC-1: 637.3;NB-4: 901.1;THP-1: 694.7;U-937: 358.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" NA NA 1300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" 17.5 17.5 5.0 7.0 5.6 132.6 14.1 7.9 9.1 44.4 2.9 12.0 4.8 31.9 1.6 8.4 37.5 6.2 16.3 4.4 7.2 21.1 12.1 15.0 2.7 10.2 7.9 31.5 7.5 2.4 22.3 5.5 8.1 22.5 1.9 0.7 6.9 4.8 4.4 16.8 9.7 8.1 7.2 14.0 8.0 9.1 6.2 2.6 12.8 1.0 0.8 19.2 28.2 6.0 2.6 3.5 0.0 2.9 33.7 45.3 79.2 139.3 37.9 15.6 15.7 0.1 0.0 0.4 1.7 70.2 0.8 1.6 0.4 0.2 10.7 0.6 22.9 363.0 0.1 0.0 21.3 0.2 637.3 33.7 0.2 1.9 2.3 0.1 17.9 16.1 4.1 2.2 29.0 2.6 3.1 901.1 1.6 0.3 4.6 30.7 0.2 0.2 0.8 0.4 0.0 3.8 4.2 0.0 58.1 0.0 0.9 694.7 100.3 1.1 41.6 0.7 0.7 2.1 2.2 0.5 47.3 358.7 44.2 1.4 24.3 0.4 0.9 11.5 0.1 0.6 0.3 0.2 17.7 0.4 2.0 4.5 1.6 5.7 5.6 4.8 0.2 8.2 5.0 5.6 7.9 9.1 4.4 7.2 10.2 7.9 8.1 7.2 6.2 6.0 12.4 3.2 5.4 10.4 3.9 32.0 32.2 2.9 27.3 20.5 30.8 31.9 3.4 8.6 4.0 29.5 10.4 8.6 5.0 1.7 119.3 11.0 6.5 17.0 70.7 16.9 26.5 36.4 9.0 3.1 72.4 107.2 4.1 14.1 5.7 18.9 51.4 6.3 49.4 21.9 8.3 4.5 10.2 21.5 73.3 19.9 70.8 29.6 78.2 9.4 11.2 70.4 14.4 8.0 12.9 3.1 1.7 67.4 0.9 21.4 0.5 13.7 5.0 20.7 65.7 20.2 59.2 17.2 21.7 26.3 45.9 18.3 5.8 56.7 3.5 17.8 CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 420.3" "Cell type enhanced" "Detected in some" "Adipocytes: 76.3;Endothelial cells: 27.9;Fibroblasts: 126.4;Hepatic stellate cells: 57.5;Leydig cells: 30.1;Microglial cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 297.9;ASC TERT1: 591.9;U-2197: 120.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" NA NA 6540000000 25000000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" 420.3 51.0 44.4 9.3 46.4 1.7 214.8 45.5 66.6 89.4 50.9 83.9 31.6 60.4 17.1 49.9 41.1 35.6 259.9 43.0 42.9 131.4 29.0 201.2 33.1 51.3 56.1 26.0 14.6 14.3 27.7 142.8 48.0 33.5 37.4 0.7 49.8 19.1 74.8 149.7 78.2 25.5 44.8 264.5 43.5 113.2 50.7 10.1 88.4 68.0 8.2 100.9 74.9 43.0 0.0 0.0 0.1 0.2 297.9 591.9 0.0 40.1 62.9 1.2 6.2 0.0 0.0 0.1 0.1 3.1 0.0 0.1 0.0 0.1 0.1 0.3 0.9 0.6 0.1 0.1 0.5 0.1 0.7 47.5 0.1 0.3 0.1 0.4 0.5 0.3 0.0 1.7 0.5 0.2 0.0 2.2 0.0 0.0 0.6 0.0 0.1 2.2 0.0 0.0 0.3 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 4.5 0.2 120.6 0.1 1.0 1.2 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.4 46.4 45.5 66.6 43.0 42.9 51.3 56.1 48.0 44.8 50.7 43.0 76.3 0.0 0.0 1.6 0.3 3.4 0.0 0.0 1.8 0.0 0.7 0.3 0.8 1.5 0.0 0.0 0.0 0.0 0.5 0.0 3.9 0.0 4.0 0.3 16.9 27.9 0.0 2.7 0.8 0.2 0.0 126.4 3.1 0.3 0.0 0.0 57.5 0.3 0.9 0.0 0.6 0.0 0.0 1.2 9.5 19.5 30.1 2.2 3.6 69.3 0.7 0.4 0.0 1.5 0.7 0.1 0.0 6.4 0.5 0.0 0.0 0.0 0.0 0.3 0.0 1.0 12.3 0.0 0.0 0.7 3.8 0.1 0.7 0.4 0.0 0.0 CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;choroid plexus: 49.5" "Cell type enhanced" "Detected in some" "Macrophages: 93.7;Muller glia cells: 32.0;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 106.2" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cell line enriched" "Detected in some" 7 "HEL: 91.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" 1.1 1.0 75.6 0.5 119.1 8.2 0.9 123.8 101.7 2.8 49.5 5.8 0.5 0.8 1.1 1.2 1.2 2.1 22.7 73.9 85.2 0.5 0.3 1.5 0.2 150.9 106.2 0.8 0.2 0.1 0.6 0.7 135.2 2.1 0.8 2.3 2.2 3.2 3.1 0.7 1.7 0.8 113.4 2.8 1.4 0.1 110.2 0.1 0.5 0.9 0.0 1.2 2.6 182.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.2 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.2 20.8 0.7 0.9 0.1 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.4 30.0 75.6 119.1 123.8 101.7 73.9 85.2 150.9 106.2 135.2 113.4 110.2 182.4 0.5 0.0 0.0 6.5 0.4 1.0 0.1 0.0 1.2 0.2 1.3 5.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.4 0.0 0.0 93.7 5.4 0.0 1.5 32.0 0.0 20.6 106.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 3.4 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.6;retina: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 497.7;Inhibitory neurons: 143.6;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 4.0;NTERA-2: 8.9;PC-3: 4.8;RH-30: 8.2;U-251 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" "HPA001502: AB_1078542" "unprognostic (1.33e-2)" "unprognostic (1.00e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-4)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-2)" "unprognostic (3.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.35e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" 1.5 2.6 8.4 0.3 12.2 0.2 1.4 22.6 16.4 1.0 0.0 0.7 0.1 0.3 0.5 0.0 1.3 0.1 0.8 20.3 0.0 0.1 0.7 1.2 0.9 0.0 0.0 0.6 2.5 0.0 1.6 0.1 0.0 0.7 0.0 17.9 0.5 0.1 4.7 0.8 0.6 0.1 0.0 0.5 1.2 0.6 0.0 0.9 0.9 1.3 1.0 0.6 0.9 5.3 0.0 5.9 4.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 2.0 0.0 8.9 0.0 4.8 0.0 8.2 0.0 0.0 0.0 3.9 1.6 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.1 1.9 0.0 5.3 3.1 0.0 3.4 0.8 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.9 0.8 0.2 0.0 0.0 0.0 0.0 0.2 0.1 8.4 12.2 22.6 16.4 20.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.3 16.0 1.3 111.7 9.0 1.3 0.5 0.0 1.2 17.8 0.3 0.6 5.7 1.5 5.6 0.0 20.9 0.1 2.1 0.4 0.0 0.3 0.3 1.0 13.6 0.3 0.0 0.8 497.7 2.3 0.0 6.7 0.0 1.3 1.3 1.0 0.0 2.1 0.1 23.5 143.6 0.5 0.0 0.0 2.6 0.0 0.6 0.2 0.0 15.9 0.2 12.7 0.0 93.5 10.6 0.6 0.1 1.5 3.1 2.0 1.3 0.3 0.0 86.1 0.0 0.6 0.9 6.0 7.7 0.1 1.8 0.0 2.9 1.5 0.4 0.0 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNTLN "bA340N12.1, C9orf101, C9orf39, FLJ20276" ENSG00000044459 Centlein Q9NXG0 9 17134982-17503923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 91.8;Spermatocytes: 84.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cell line enhanced" "Detected in many" "HEL: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007201, HPA036728, HPA036729" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Centrosome "Nucleoplasm, Cytosol" "HPA007201: AB_2667775, HPA036728: AB_10670847, HPA036729: AB_10670240" "unprognostic (1.97e-2)" "unprognostic (2.81e-3)" "unprognostic (1.81e-1)" "unprognostic (2.48e-1)" "unprognostic (1.55e-1)" "unprognostic (1.60e-1)" "unprognostic (7.71e-2)" "unprognostic (1.68e-1)" "unprognostic (7.71e-3)" "unprognostic (5.07e-3)" "unprognostic (1.06e-1)" "unprognostic (6.65e-2)" "unprognostic (2.47e-1)" "unprognostic (5.38e-2)" "unprognostic (3.35e-2)" "unprognostic (1.37e-1)" "unprognostic (5.80e-2)" 4.4 2.4 2.3 2.1 2.4 7.3 3.5 7.7 2.2 5.0 3.3 4.5 1.2 7.1 2.4 2.7 4.3 4.2 2.3 1.7 2.6 2.4 10.5 2.8 2.7 2.7 3.1 8.8 1.7 4.4 2.2 3.6 3.0 2.7 2.2 2.1 1.6 3.2 1.6 1.9 2.2 4.5 2.6 3.9 1.9 5.2 2.5 2.8 3.1 2.5 1.6 3.5 3.5 2.8 8.3 5.6 12.1 6.8 5.8 13.6 0.4 9.5 6.3 7.0 9.5 0.4 2.7 6.0 1.5 6.6 7.5 0.3 14.1 3.9 10.9 0.3 4.9 35.5 11.7 2.0 6.4 4.9 7.4 8.6 2.0 5.8 5.7 6.5 10.0 2.2 1.3 1.1 11.3 0.6 4.0 7.8 9.4 1.4 10.3 5.8 11.2 3.0 4.1 2.0 7.6 7.9 11.6 0.2 3.0 4.8 2.3 12.3 7.5 9.5 3.7 10.4 8.3 4.7 6.1 0.1 4.4 6.1 4.4 0.2 1.3 0.0 0.0 1.6 0.0 0.1 0.1 0.0 0.7 0.1 0.0 0.0 0.1 0.5 3.9 0.7 0.1 0.2 2.3 2.4 7.7 2.2 1.7 2.6 2.7 3.1 3.0 2.6 2.5 2.8 32.0 6.4 17.6 59.7 1.6 8.8 13.7 6.1 13.1 12.3 3.6 5.8 13.4 7.2 3.4 9.2 0.0 2.5 1.1 2.4 5.9 10.1 16.3 23.4 30.7 24.9 2.4 17.1 20.3 12.0 5.2 29.2 4.1 17.0 7.6 42.4 20.0 38.8 18.4 20.2 37.2 5.9 4.1 40.3 11.6 8.8 45.7 24.0 8.8 91.8 31.0 21.4 1.0 70.4 29.6 4.0 0.8 30.9 1.8 3.8 5.3 8.5 6.7 8.1 13.1 34.2 21.3 84.3 48.9 5.3 5.5 1.0 1.7 31.6 5.5 6.3 CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 158.2" "Group enriched" "Detected in many" 5 "Astrocytes: 763.9;Excitatory neurons: 844.8;Inhibitory neurons: 699.0;Oligodendrocyte precursor cells: 1021.4" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A549: 224.4;HaCaT: 40.3;SCLC-21H: 68.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" NA NA 450000000 "Cluster 17: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" 3.9 33.2 64.0 2.5 75.3 0.2 8.8 119.4 84.2 14.1 0.0 3.1 1.7 11.5 2.6 9.1 2.2 11.7 0.8 93.6 59.8 12.4 1.2 4.4 4.5 72.6 94.7 49.2 6.0 1.4 10.4 0.3 70.0 27.8 3.8 26.8 5.4 27.7 0.8 12.8 3.0 10.6 129.0 8.2 5.0 9.4 79.2 1.0 1.2 1.6 3.9 21.5 6.6 158.2 0.1 224.4 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.3 0.3 0.1 0.1 0.0 0.0 40.3 6.0 11.2 0.0 0.2 2.4 0.0 0.7 0.0 0.0 0.0 0.7 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.2 1.5 0.2 0.1 0.0 1.0 0.3 0.0 0.0 68.5 40.3 0.1 2.5 2.7 1.0 0.1 0.6 0.0 0.1 4.3 0.1 10.0 2.8 0.1 0.0 0.3 0.0 0.9 2.6 0.5 0.7 0.3 0.2 0.3 0.4 0.2 0.2 0.1 0.4 0.4 0.2 1.2 0.7 0.4 0.9 0.2 0.0 64.0 75.3 119.4 84.2 93.6 59.8 72.6 94.7 70.0 129.0 79.2 158.2 0.3 0.0 5.9 763.9 0.1 5.2 1.1 1.6 4.0 32.1 0.4 1.8 0.7 0.0 4.5 5.5 29.2 0.0 0.0 0.0 1.9 0.0 34.9 4.3 7.1 0.7 0.0 0.0 844.8 0.0 0.0 13.3 0.0 0.3 0.0 5.0 0.0 0.0 0.1 11.8 699.0 0.0 2.0 0.0 4.0 149.5 62.7 0.1 10.6 54.4 0.0 34.6 0.0 1021.4 23.9 0.7 0.0 60.2 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.5 3.6 0.6 0.8 2.1 13.5 0.0 0.5 0.3 0.0 0.2 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.1;placenta: 28.3" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Cardiomyocytes: 36.9;Extravillous trophoblasts: 75.3;Inhibitory neurons: 63.3;Respiratory ciliated cells: 51.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 23.4;BEWO: 7.6;HSkMC: 24.0;SuSa: 11.1" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" NA NA 290000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" 2.6 1.4 2.6 0.6 3.2 0.0 1.4 3.3 1.9 24.1 11.4 7.8 0.5 12.4 2.8 2.4 7.4 3.8 4.2 2.4 5.6 1.1 1.2 7.6 0.5 2.7 6.3 3.7 1.9 0.6 1.9 28.3 3.1 3.5 2.0 0.0 5.0 10.7 1.3 6.6 1.3 7.9 1.5 0.5 2.7 2.7 4.0 0.7 1.0 6.6 0.5 6.1 6.0 2.7 0.0 3.4 0.2 0.0 1.3 23.4 7.6 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.2 0.1 0.0 24.0 0.9 0.0 0.3 0.5 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.2 3.3 1.9 2.4 5.6 2.7 6.3 3.1 1.5 4.0 2.7 6.4 0.0 1.5 66.6 0.0 5.9 2.2 2.8 2.2 0.0 0.3 0.4 36.9 0.0 8.2 0.0 0.0 27.5 0.1 0.0 0.0 0.0 7.4 24.8 10.6 6.6 0.0 0.0 16.0 0.0 75.3 28.2 0.5 1.2 0.0 0.2 2.9 0.0 6.1 0.0 63.3 0.0 16.2 0.3 3.0 1.7 15.2 0.3 5.4 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 12.4 0.0 0.1 0.1 0.1 51.3 0.0 0.0 7.3 15.0 1.2 2.5 1.0 4.1 23.3 0.4 2.1 0.2 1.3 COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Cone photoreceptor cells: 18.8;Endometrial ciliated cells: 21.1;Excitatory neurons: 23.4;Inhibitory neurons: 22.6;Oligodendrocyte precursor cells: 12.5;Respiratory ciliated cells: 16.3" "Cancer enhanced" "Detected in many" "glioma: 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 2.3;U-266/70: 9.8;U-266/84: 2.8;WM-115: 4.9" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 33.5" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA043844: AB_2732508, HPA060468: AB_2684288" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.28e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-2)" "unprognostic (5.63e-3)" "unprognostic (2.61e-2)" "unprognostic (7.58e-2)" "unprognostic (2.72e-2)" "unprognostic (7.69e-2)" "unprognostic (3.90e-3)" "unprognostic (2.33e-2)" "unprognostic (3.45e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (2.48e-3)" "unprognostic (3.09e-2)" 1.0 3.2 0.8 1.6 1.0 0.3 2.8 1.9 2.7 3.3 1.4 11.7 1.2 2.2 14.1 2.1 4.9 1.5 3.7 1.1 0.9 6.3 0.7 1.2 0.2 0.9 3.6 1.2 5.8 0.2 11.2 0.5 1.4 3.9 4.1 6.7 18.2 5.1 5.9 2.1 3.4 1.7 0.2 0.4 6.5 3.7 1.1 0.2 1.2 3.2 0.1 2.9 4.5 1.5 1.5 0.0 0.0 0.0 0.1 0.7 0.2 0.1 0.4 0.0 0.0 1.1 0.4 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 1.4 0.1 0.2 0.0 0.7 0.9 0.3 0.0 0.1 0.0 2.3 0.0 0.1 0.0 0.1 0.7 0.0 0.3 0.1 0.5 0.7 0.1 0.5 1.3 0.0 9.8 2.8 0.0 0.2 0.6 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.8 1.0 1.9 2.7 1.1 0.9 0.9 3.6 1.4 0.2 1.1 1.5 0.4 0.0 4.1 39.5 0.0 0.3 0.1 0.2 0.0 5.3 1.6 1.5 0.9 0.0 3.3 3.7 18.8 0.3 0.1 0.8 0.0 0.1 2.0 21.1 0.5 0.1 0.0 0.0 23.4 0.2 0.0 3.1 0.0 3.9 1.3 0.5 1.8 0.0 0.1 5.0 22.6 0.5 0.0 0.3 0.3 1.1 0.9 0.1 0.0 7.5 0.0 2.2 0.0 12.5 9.1 0.4 5.4 0.7 0.0 0.1 0.2 0.5 16.3 5.4 0.0 1.8 0.2 0.9 1.0 0.1 0.1 0.3 0.1 0.2 0.3 0.1 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CPED1 "C7orf58, FLJ21986" ENSG00000106034 "Cadherin like and PC-esterase domain containing 1" A4D0V7 7 120988697-121297442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 78.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.4;Microglial cells: 229.5;Peritubular cells: 81.6;Theca cells: 94.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 10.8;intermediate monocyte: 11.3;myeloid DC: 25.2;non-classical monocyte: 7.6;plasmacytoid DC: 15.0" "Group enriched" "Detected in many" 9 "dendritic cells: 25.2;monocytes: 11.3" "Cell line enhanced" "Detected in many" "BJ hTERT+: 87.6;Hep G2: 51.6;K-562: 182.3;LHCN-M2: 60.0;U-138 MG: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012058 Uncertain Approved Nucleoplasm NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA012058: AB_1845761" "unprognostic (7.94e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (4.48e-4)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (5.52e-3)" "prognostic favorable (3.00e-4)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (8.69e-2)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.28e-3)" "unprognostic (5.05e-2)" "unprognostic (3.78e-1)" "unprognostic (6.54e-4)" 55.0 18.5 2.1 6.5 2.6 0.9 10.0 2.4 2.6 25.2 5.5 16.1 9.1 32.9 13.3 16.5 15.8 26.7 21.5 1.8 2.6 7.1 44.3 16.7 1.8 4.5 3.1 78.5 3.4 1.4 3.3 24.9 4.5 28.1 15.0 1.1 4.1 36.7 17.4 2.0 11.5 38.6 4.1 17.8 10.3 5.5 4.5 1.9 3.7 38.7 1.8 20.7 6.1 5.4 6.3 0.0 0.3 0.1 14.0 40.7 0.3 25.5 87.6 8.6 23.5 0.8 0.3 0.9 0.3 14.0 9.7 0.3 0.4 0.0 22.4 0.3 0.9 7.1 0.3 51.6 24.3 0.2 0.2 16.7 0.0 20.0 0.4 6.9 4.4 0.1 182.3 12.8 60.0 0.0 0.1 0.2 0.1 0.0 1.1 0.1 34.6 17.3 0.0 0.6 0.0 2.2 0.0 0.1 0.6 0.4 0.1 0.6 2.6 50.2 1.3 42.5 24.3 5.6 0.1 0.6 5.8 0.2 2.5 2.0 10.8 0.0 0.0 11.3 0.1 1.4 0.0 0.0 25.2 0.5 0.0 0.0 0.4 0.0 7.6 15.0 0.0 2.9 2.1 2.6 2.4 2.6 1.8 2.6 4.5 3.1 4.5 4.1 4.5 5.4 19.1 19.2 0.5 12.4 2.5 3.1 0.6 0.0 1.2 0.1 0.6 1.7 20.3 1.5 0.0 0.0 0.0 0.4 8.3 0.0 0.0 0.0 0.2 0.8 23.2 6.9 0.0 2.1 0.9 0.0 2.9 48.4 0.5 0.5 0.0 11.9 28.2 21.9 4.3 3.3 14.7 0.0 0.0 14.5 28.5 1.9 21.1 23.1 3.6 229.5 5.3 14.0 1.0 1.5 0.7 0.0 0.0 81.6 3.0 1.5 0.0 0.2 0.0 0.4 0.0 9.1 32.1 0.6 0.7 1.0 2.0 0.4 0.8 94.5 0.0 2.6 CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 81.3;intestine: 75.4" "Cell type enhanced" "Detected in many" "Early spermatids: 106.8;Late spermatids: 202.5;Oligodendrocytes: 35.6;Peritubular cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "BJ: 18.4;fHDF/TERT166: 71.8;SuSa: 28.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" NA NA 62000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" 29.1 6.4 3.9 5.9 7.2 0.0 20.8 9.2 2.6 5.8 81.3 75.4 6.2 10.2 59.8 18.4 16.0 11.2 18.0 3.5 7.2 11.2 2.4 7.0 2.7 16.1 10.7 16.7 5.2 2.5 10.9 1.2 11.6 15.1 7.0 0.5 9.3 12.7 3.8 7.3 14.9 56.9 20.0 16.8 19.9 9.6 10.4 7.8 15.0 7.9 6.6 28.3 9.2 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.4 0.7 1.1 0.1 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 28.0 0.5 0.0 0.0 0.1 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 7.2 9.2 2.6 3.5 7.2 16.1 10.7 11.6 20.0 10.4 18.3 22.3 0.0 0.6 0.3 0.1 2.2 0.0 0.2 6.2 0.0 0.3 0.4 2.4 0.0 0.0 1.8 0.0 8.3 0.1 0.2 1.9 0.4 106.8 0.2 0.2 26.1 0.0 0.0 5.0 0.2 0.3 23.0 1.1 0.3 0.0 0.1 16.8 0.0 0.3 1.7 0.5 0.7 0.0 0.0 2.7 202.5 10.8 0.6 3.6 0.0 0.0 0.0 0.0 1.0 35.6 0.1 0.1 79.0 1.4 0.0 0.4 0.0 0.0 0.1 0.0 1.6 2.0 1.3 1.9 0.6 2.0 5.1 0.2 0.0 2.7 0.2 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CRMP1 "DPYSL1, DRP-1" ENSG00000072832 "Collapsin response mediator protein 1" Q14194 4 5748084-5893086 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.7;pituitary gland: 67.3;retina: 57.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 148.9;Excitatory neurons: 40.8;Horizontal cells: 210.3;Inhibitory neurons: 44.5;Muller glia cells: 78.4" "Cancer enhanced" "Detected in all" "glioma: 37.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 81.0;HAP1: 117.2;NTERA-2: 84.3;REH: 229.4;RH-30: 129.6;SCLC-21H: 167.2;SH-SY5Y: 105.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035640, CAB037313" Approved Supported Centrosome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Centrosome Cytosol "CAB037313: AB_1078571, HPA035640: AB_10670838" "unprognostic (1.56e-1)" "unprognostic (7.22e-2)" "unprognostic (5.14e-2)" "unprognostic (8.08e-3)" "unprognostic (2.80e-1)" "unprognostic (2.22e-1)" "unprognostic (1.84e-2)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (9.71e-2)" "prognostic favorable (4.54e-4)" "unprognostic (2.26e-1)" "unprognostic (8.52e-3)" "unprognostic (1.21e-2)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.60e-3)" 1.8 9.8 53.0 2.7 55.9 0.1 0.9 45.0 58.0 9.6 10.7 4.4 1.3 21.9 0.1 2.7 4.9 5.1 2.8 59.7 57.9 2.1 0.3 5.7 1.9 31.0 35.2 7.9 5.7 0.7 67.3 5.4 41.0 3.2 1.6 57.6 2.7 3.1 0.5 3.7 2.9 14.5 30.8 1.1 3.7 3.0 47.1 1.2 2.4 1.1 1.0 2.6 2.9 38.2 1.3 2.7 81.0 2.8 0.1 0.0 0.4 3.2 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 27.2 1.9 117.2 0.0 0.0 2.2 0.9 0.0 4.0 0.6 1.4 0.1 0.7 1.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.3 1.3 0.0 0.4 0.0 84.3 0.0 2.6 229.4 129.6 20.2 0.0 0.2 167.2 105.8 0.0 0.6 1.4 54.2 0.8 0.1 6.8 3.8 27.3 2.3 2.6 14.8 2.2 0.1 9.8 0.9 69.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.0 55.9 45.0 58.0 59.7 57.9 31.0 35.2 41.0 30.8 47.1 38.2 1.0 0.0 1.1 23.8 0.0 0.4 0.0 1.5 0.0 148.9 0.0 0.0 1.5 0.0 0.0 0.0 18.8 0.1 0.0 0.0 0.0 0.1 2.2 0.4 13.6 6.3 2.4 1.3 40.8 0.0 0.2 3.5 3.1 0.5 0.0 2.4 0.0 0.0 0.5 210.3 44.5 0.0 0.0 0.0 0.0 5.5 0.6 0.2 1.8 6.5 0.0 78.4 0.0 33.2 2.9 0.4 0.0 0.4 0.0 0.4 0.0 0.0 0.0 22.8 6.6 0.4 6.2 1.0 12.4 1.1 0.1 0.3 0.2 1.5 0.0 0.1 CRYM DFNA40 ENSG00000103316 "Crystallin mu" Q14894 16 21238874-21303083 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.7;heart muscle: 175.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.0;Ionocytes: 114.0;Muller glia cells: 640.7;Proximal tubular cells: 190.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 21 "plasmacytoid DC: 82.0" "Lineage enriched" "Detected in many" 21 "dendritic cells: 82.0" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 100.3" "Group enriched" "Detected in all" 11 "amygdala: 124.0;basal ganglia: 275.1;cerebral cortex: 124.7;hippocampal formation: 324.3;white matter: 128.4" "Low region specificity" "Detected in all" "HPA019086, HPA030619" Enhanced Supported Cytosol NA NA 150000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA019086: AB_1847260, HPA030619: AB_2673551" "unprognostic (1.32e-1)" "unprognostic (2.93e-3)" "unprognostic (8.96e-2)" "unprognostic (1.44e-1)" "unprognostic (2.13e-1)" "unprognostic (4.62e-2)" "unprognostic (2.88e-1)" "unprognostic (5.75e-3)" "unprognostic (2.81e-1)" "unprognostic (7.37e-2)" "unprognostic (2.05e-2)" "unprognostic (5.95e-2)" "unprognostic (2.11e-3)" "unprognostic (7.79e-3)" "unprognostic (2.49e-2)" "unprognostic (1.87e-3)" "unprognostic (1.31e-1)" 1.9 0.8 37.4 0.9 78.7 1.0 2.7 40.6 62.2 3.7 13.6 6.9 1.6 1.0 0.2 7.6 1.1 7.0 175.3 54.0 31.6 64.4 14.2 8.5 1.1 13.9 19.8 0.3 1.8 8.9 55.6 0.4 15.6 35.4 8.4 54.7 20.6 0.2 13.4 4.1 2.6 0.3 14.1 0.3 1.3 5.1 20.5 0.3 0.4 0.9 3.8 21.8 3.6 31.3 0.2 4.0 0.0 0.0 0.2 0.4 0.7 0.0 2.1 0.1 0.2 0.2 0.2 0.3 1.0 0.0 1.8 0.6 5.4 0.0 0.0 0.0 0.8 23.2 0.1 2.3 0.0 0.1 2.2 0.8 0.0 0.8 1.0 0.0 0.0 0.5 0.0 0.4 0.7 0.3 0.0 0.9 9.7 1.6 0.1 0.1 0.0 0.5 100.3 0.1 3.7 5.2 0.2 0.1 2.6 4.8 0.1 0.0 0.0 0.5 0.7 6.8 0.0 0.2 0.0 0.5 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.2 0.0 0.0 0.1 3.9 0.0 0.0 0.3 0.0 0.0 82.0 0.0 1.2 37.4 78.7 40.6 62.2 54.0 31.6 13.9 19.8 15.6 14.1 20.5 31.3 0.3 0.0 20.1 5.2 4.1 2.3 25.4 16.3 0.0 6.3 0.4 11.7 126.0 2.8 56.1 14.7 4.2 0.0 11.4 7.1 17.6 0.1 19.7 3.2 1.5 3.0 13.1 4.8 43.8 0.0 0.0 7.1 6.1 7.7 1.3 1.3 0.4 8.3 0.1 1.7 5.9 20.6 114.0 1.6 0.7 12.4 0.0 1.5 33.8 10.3 0.7 640.7 0.0 7.1 6.6 0.4 2.8 0.0 0.3 19.0 7.5 190.1 19.9 26.2 0.0 0.2 4.3 6.7 7.3 0.2 1.3 0.1 1.1 0.1 8.2 68.0 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 347.2;Distal tubular cells: 172.1;Fibroblasts: 566.4;Kupffer cells: 191.8;Smooth muscle cells: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 509.6;BJ hTERT+: 303.5;BJ hTERT+ SV40 Large T+: 294.9;BJ hTERT+ SV40 Large T+ RasG12V: 441.2;fHDF/TERT166: 501.8;HSkMC: 1293.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" NA NA 1030000 560000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" 366.8 82.6 19.4 143.8 20.2 35.1 237.4 19.1 28.1 268.4 24.5 124.3 53.6 360.7 54.3 138.5 122.1 263.3 190.3 19.4 18.6 124.8 252.8 71.0 215.8 22.3 21.1 112.3 131.2 126.7 21.3 8.5 19.1 47.8 115.5 2.1 116.3 66.2 158.9 99.4 96.5 343.5 19.9 356.6 45.4 19.4 21.0 142.6 103.4 181.3 119.7 107.0 174.3 17.7 0.0 0.0 0.4 0.6 509.6 78.9 0.4 187.7 303.5 294.9 441.2 0.0 0.1 0.2 1.9 501.8 0.0 0.1 0.8 0.2 97.1 187.2 2.4 0.0 0.0 0.0 172.8 0.4 0.9 1293.8 0.0 63.8 0.1 0.0 0.2 0.1 0.1 0.0 1.0 0.4 0.7 0.6 32.2 0.0 0.6 0.8 0.3 224.3 0.2 0.0 0.6 0.6 0.3 0.7 0.0 63.6 272.2 0.4 0.4 0.4 0.5 205.0 0.2 0.2 0.1 0.1 0.6 0.3 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 20.2 19.1 28.1 19.4 18.6 22.3 21.1 19.1 19.9 21.0 17.7 347.2 0.0 1.1 1.3 1.4 76.3 0.3 0.0 9.6 1.5 8.1 14.0 25.0 10.0 0.6 5.5 0.0 0.3 2.1 0.0 172.1 0.8 2.2 1.7 46.8 134.1 0.0 0.0 0.6 20.5 0.3 566.4 1.5 1.0 0.0 0.4 55.6 2.5 2.6 0.0 6.6 3.9 0.0 191.8 110.1 3.7 70.2 27.9 135.2 74.0 0.0 1.9 0.0 12.1 0.1 3.0 0.0 8.6 1.0 1.0 0.1 25.5 0.0 0.8 85.5 43.7 146.1 1.8 5.9 6.3 62.7 0.7 9.6 33.2 0.5 0.5 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.5;liver: 40.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 58.8;Gastric mucus-secreting cells: 57.6;Paneth cells: 51.9;Proximal enterocytes: 125.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.1;eosinophil: 14.8" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 17.6;HaCaT: 32.0;Hep G2: 9.8;Karpas-707: 20.9;OE19: 46.3" HPA058960 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" 3.2 1.1 0.6 1.2 0.9 0.9 2.7 0.6 1.5 6.0 0.4 15.1 39.1 1.5 0.5 18.1 3.2 2.4 1.5 0.9 2.4 1.8 40.1 1.2 0.5 0.9 1.1 1.6 0.3 0.0 0.5 0.5 1.1 5.0 7.8 0.1 4.3 1.0 0.6 21.1 41.5 1.9 0.7 1.0 12.0 0.2 0.7 0.8 0.9 0.9 2.6 10.5 11.2 1.9 0.0 4.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.6 0.5 0.0 0.0 0.3 32.0 0.0 0.0 0.0 2.0 0.0 0.0 1.7 9.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.1 0.0 46.3 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.1 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.1 0.0 14.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.6 1.5 0.9 2.4 0.9 1.1 1.1 0.7 0.7 1.9 6.3 0.0 1.8 2.6 0.5 14.0 10.0 8.3 13.1 0.0 0.5 0.3 1.0 5.7 7.1 0.0 0.0 0.1 0.0 58.8 0.0 0.6 1.6 0.2 0.1 3.0 7.8 8.0 0.2 0.0 0.1 3.8 57.6 0.3 0.0 0.0 1.4 30.3 0.4 0.0 0.2 24.8 2.0 0.9 1.6 3.2 4.1 0.3 1.8 0.0 0.0 2.7 0.0 0.0 0.4 1.9 51.9 1.2 0.2 3.5 125.3 2.2 4.9 0.1 0.0 0.3 2.5 0.4 0.1 20.5 21.2 0.3 0.5 0.1 29.6 24.8 CYP4X1 MGC40051 ENSG00000186377 "Cytochrome P450 family 4 subfamily X member 1" Q8N118 1 47023669-47050751 "Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.1;salivary gland: 31.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 37.5;Club cells: 59.0;Excitatory neurons: 37.4;Respiratory ciliated cells: 104.6" "Cancer enhanced" "Detected in many" "breast cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.6;CACO-2: 4.6;NTERA-2: 2.1;SCLC-21H: 2.7;T-47d: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017661 Approved NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA017661: AB_2669633" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.53e-1)" "unprognostic (1.78e-2)" "unprognostic (9.88e-2)" "unprognostic (1.56e-3)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.76e-2)" "unprognostic (3.03e-2)" "unprognostic (1.79e-3)" "unprognostic (3.65e-2)" "unprognostic (8.56e-2)" "unprognostic (5.03e-2)" 11.6 3.2 8.2 0.7 8.5 0.1 14.9 5.2 10.2 37.1 2.8 1.6 1.7 2.1 2.7 14.7 9.3 1.6 8.6 8.7 12.1 5.9 10.5 8.8 1.9 4.5 5.6 1.2 1.7 1.7 3.8 1.1 5.7 8.0 1.9 2.3 31.1 2.9 4.6 7.1 1.4 1.9 4.1 0.6 22.3 4.0 9.2 1.1 5.0 4.0 9.1 3.3 7.2 6.4 0.0 0.0 0.0 0.0 2.6 0.2 0.1 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.3 0.0 0.4 0.2 2.7 0.0 0.0 0.2 0.0 0.1 9.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 8.5 5.2 10.2 8.7 12.1 4.5 5.6 5.7 4.1 9.2 6.4 4.4 22.4 17.0 2.3 0.0 2.5 26.9 37.5 25.0 2.4 31.0 0.9 0.8 1.5 59.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 8.4 7.6 0.8 4.0 0.0 0.0 37.4 0.7 0.0 7.1 4.1 1.4 0.0 0.0 1.1 2.8 3.9 0.0 29.3 0.2 18.3 0.6 0.7 8.6 10.5 0.5 5.4 4.7 0.0 0.1 0.0 1.0 2.0 0.1 0.0 20.7 0.0 8.4 0.5 1.7 104.6 0.8 0.0 2.0 19.1 0.5 3.6 21.4 1.4 0.1 0.5 0.1 1.9 31.8 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DCAF12L2 WDR40C ENSG00000198354 "DDB1 and CUL4 associated factor 12 like 2" Q5VW00 X 126163499-126166289 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.3;epididymis: 21.4" "Cell type enriched" "Detected in some" 7 "Granulosa cells: 11.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HAP1: 2.6;NTERA-2: 2.2;U-2 OS: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044737, HPA048981, HPA053138" Approved Uncertain Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA044737: AB_2679067, HPA048981: AB_2680586, HPA053138: AB_2682054" "unprognostic (1.16e-4)" "unprognostic (8.83e-3)" "unprognostic (2.93e-1)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "unprognostic (3.02e-1)" "unprognostic (3.34e-3)" "unprognostic (1.16e-1)" "unprognostic (8.47e-4)" "unprognostic (1.56e-2)" "unprognostic (4.05e-2)" "unprognostic (3.86e-2)" "unprognostic (2.51e-1)" 0.8 0.9 1.9 0.0 2.0 0.0 0.4 0.1 2.2 1.4 0.0 0.7 0.0 2.4 21.4 0.1 2.3 0.1 0.0 2.5 3.5 0.2 0.0 0.0 0.1 9.3 1.5 1.4 0.0 2.5 1.3 0.0 4.2 1.5 0.0 0.2 0.3 4.3 0.1 0.2 0.2 1.3 1.6 0.0 0.3 5.5 3.1 0.0 0.1 0.9 0.2 1.2 0.5 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 0.1 2.2 2.5 3.5 9.3 1.5 4.2 1.6 3.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DCDC2C ENSG00000214866 "Doublecortin domain containing 2C" A8MYV0 2 3703575-3848008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Group enriched" "Detected in some" 7 "Early spermatids: 171.3;Late spermatids: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA045848 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA045848: AB_10961120" "unprognostic (2.63e-2)" "unprognostic (1.81e-1)" "unprognostic (3.81e-3)" "unprognostic (6.98e-2)" 0.1 0.0 0.6 0.0 0.5 0.4 0.1 0.9 0.9 0.0 1.2 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.5 0.5 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 4.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.9 0.9 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.3 0.0 0.4 2.3 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 59.9 5.6 0.1 0.0 15.9 0.0 0.0 0.0 0.0 0.2 0.3 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1218.7;Fibroblasts: 7960.2;Leydig cells: 6281.9;Peritubular cells: 1856.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cell line enhanced" "Detected in many" "ASC diff: 3291.1;ASC TERT1: 2371.6;BJ hTERT+: 2546.6;HSkMC: 2289.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 544.7" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" NA NA 1900000 "Cluster 46: Basophils - DNA binding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" 1522.3 1171.7 60.6 272.0 80.0 4.4 2342.2 63.5 119.2 1493.0 111.6 549.9 163.5 1308.5 1302.0 932.8 1213.4 1802.7 2108.9 66.8 60.3 394.8 459.6 955.8 130.4 68.9 60.9 2681.4 257.9 80.2 112.0 1534.8 75.7 451.6 493.0 3.1 362.5 462.3 469.0 713.4 336.6 1027.8 70.2 20.0 434.5 279.6 72.8 183.0 479.3 1328.3 293.6 1895.5 783.7 57.9 0.2 0.4 4.4 0.6 3291.1 2371.6 6.2 608.7 2546.6 28.8 28.5 0.3 0.9 1.1 0.5 523.5 0.6 2.1 0.8 1.9 4.9 0.7 0.5 0.6 20.4 0.1 717.4 1.3 1.4 2289.4 8.9 78.3 38.5 12.1 1.0 0.2 0.8 0.7 63.0 0.6 1.5 10.8 1.2 0.4 1.6 0.7 2.3 2.8 3.4 0.5 2.7 11.9 10.3 1.1 0.9 1.8 0.6 0.4 0.9 132.3 1.2 497.5 0.6 3.3 3.1 2.0 8.0 2.0 0.8 24.5 0.3 0.6 0.3 0.1 0.3 0.3 0.3 0.2 0.1 0.6 0.4 0.4 2.7 0.4 0.2 0.7 0.2 0.0 60.6 80.0 63.5 119.2 66.8 60.3 68.9 60.9 75.7 70.2 72.8 57.9 351.1 41.7 44.1 2.3 4.1 609.1 5.4 0.0 264.6 1.9 25.5 31.5 154.7 10.0 11.8 20.2 0.0 31.2 12.8 0.0 1.9 1.0 25.0 39.4 1218.7 158.7 0.0 2.7 0.8 0.0 30.0 7960.2 54.0 22.0 21.5 0.2 214.9 1.4 58.8 0.0 17.1 0.1 0.0 2.8 962.7 103.0 6281.9 52.5 606.5 122.7 0.0 3.3 0.0 0.0 1.4 2.7 0.5 1856.9 23.2 5.8 0.0 0.4 5.8 0.7 210.4 236.8 408.2 13.4 9.2 36.8 482.5 63.9 72.3 70.2 0.0 10.7 DENND2A "FAM31D, KIAA1277" ENSG00000146966 "DENN domain containing 2A" Q9ULE3 7 140518420-140673993 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.9;Horizontal cells: 89.2;Oligodendrocyte precursor cells: 72.4;Paneth cells: 69.5" "Cancer enriched" "Detected in all" 6 "glioma: 28.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 57.7;BJ hTERT+: 60.8;PC-3: 29.1;RPTEC TERT1: 72.7;U-2197: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.02e-2)" "unprognostic (1.14e-1)" "prognostic favorable (9.35e-4)" "unprognostic (1.78e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (3.05e-6)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (3.54e-2)" "unprognostic (2.38e-3)" 15.4 3.9 28.9 2.5 32.5 0.6 11.0 23.5 25.8 25.0 46.9 12.0 3.9 26.2 5.1 9.6 30.7 11.1 16.1 25.2 28.8 14.5 3.1 17.6 2.3 43.7 39.7 21.7 2.2 5.0 26.3 15.5 33.7 11.4 5.6 11.5 2.6 5.4 7.1 3.9 8.9 16.0 34.6 12.2 6.6 2.1 32.1 0.8 3.7 7.8 1.8 12.1 11.4 26.2 0.2 0.9 57.7 0.5 6.2 1.1 12.4 2.2 60.8 9.5 15.3 0.0 0.1 0.1 0.4 0.6 10.2 0.2 11.0 0.8 17.8 0.0 1.0 0.0 0.2 0.0 1.6 0.2 0.1 2.8 0.6 13.9 2.1 24.9 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 12.3 0.1 29.1 2.1 3.7 0.2 72.7 0.1 4.6 14.5 0.0 0.0 0.0 16.7 0.1 0.6 0.0 10.9 2.2 32.1 5.9 0.3 0.0 0.1 0.9 0.1 3.9 1.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.1 1.2 0.3 0.1 0.2 0.1 0.0 28.9 32.5 23.5 25.8 25.2 28.8 43.7 39.7 33.7 34.6 32.1 26.2 13.8 0.0 3.0 34.9 0.5 1.3 1.9 0.1 0.6 7.4 1.9 1.0 4.3 0.0 1.3 0.0 8.4 1.0 0.3 114.9 7.9 0.0 1.4 0.4 8.3 4.6 9.6 0.0 10.0 0.0 4.9 14.8 1.1 0.3 11.4 22.4 9.7 0.7 2.4 89.2 23.2 37.1 0.0 0.3 2.1 1.0 18.6 0.6 1.8 32.8 0.1 16.2 0.0 72.4 42.3 0.1 69.5 10.5 0.0 2.2 3.8 0.1 1.0 10.5 13.1 11.8 11.3 0.1 0.9 0.2 0.4 0.4 1.1 0.2 42.7 1.2 DENND2B "HTS1, p126, ST5" ENSG00000166444 "DENN domain containing 2B" P78524 11 8693351-8910951 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 3.2;Cardiomyocytes: 6.2;Cytotrophoblasts: 3.7;Extravillous trophoblasts: 1.8;Fibroblasts: 7.1;Hofbauer cells: 5.8;Smooth muscle cells: 5.7;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.9" "Lineage enriched" "Detected in single" 4 "monocytes: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046796 Approved Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA046796: AB_2679812" "unprognostic (1.88e-3)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (1.88e-2)" "unprognostic (4.17e-2)" "unprognostic (2.46e-1)" "unprognostic (6.42e-2)" "unprognostic (1.17e-1)" "unprognostic (1.72e-1)" "unprognostic (5.56e-2)" "unprognostic (3.67e-2)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (1.60e-1)" "unprognostic (1.54e-1)" 26.3 60.0 22.0 19.2 20.4 3.4 26.6 26.6 23.2 72.7 38.2 85.4 28.8 130.3 33.2 62.7 104.6 34.6 35.0 19.1 22.3 29.4 27.4 28.8 12.1 29.7 32.6 69.2 27.5 15.4 21.5 26.4 18.3 45.4 26.7 36.5 37.5 62.9 21.9 22.2 30.3 117.2 21.3 59.7 56.9 41.0 28.0 17.5 36.6 11.1 15.1 65.0 50.4 17.1 32.6 4.9 51.8 9.0 16.8 17.6 2.5 28.9 95.8 27.5 25.4 6.8 34.0 1.0 17.2 52.7 12.1 32.2 10.0 41.7 10.8 4.4 12.7 0.0 16.7 22.8 26.9 0.2 0.2 60.8 11.6 15.6 20.1 56.0 5.5 5.0 6.7 2.8 45.4 3.5 1.8 1.5 7.9 32.2 7.7 1.1 31.5 2.0 37.5 23.4 9.8 31.7 25.7 32.1 19.8 17.7 5.4 1.1 14.9 15.8 24.7 50.6 22.8 8.0 15.5 0.2 24.1 0.2 30.4 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.0 2.9 0.0 0.1 0.4 22.0 20.4 26.6 23.2 19.1 22.3 29.7 32.6 18.3 21.3 28.0 17.1 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.8 7.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 DGKB "DAGK2, DGK, DGK-BETA, KIAA0718" ENSG00000136267 "Diacylglycerol kinase beta" Q9Y6T7 7 14145049-14974777 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 32.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 937.7;Inhibitory neurons: 576.6;Oligodendrocyte precursor cells: 254.3" "Cancer enriched" "Detected in single" 11 "glioma: 1.7" "Group enriched" "Detected in many" 7 "basal ganglia: 32.3;cerebral cortex: 14.4;hippocampal formation: 9.2;hypothalamus: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;fHDF/TERT166: 2.6;SCLC-21H: 1.3;U-266/70: 3.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 192.8" HPA020321 Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA020321: " "unprognostic (9.89e-2)" "unprognostic (9.72e-5)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (4.32e-2)" "unprognostic (3.37e-1)" "unprognostic (7.34e-2)" "unprognostic (5.91e-2)" "unprognostic (6.19e-2)" "unprognostic (8.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (5.98e-2)" "unprognostic (2.37e-3)" "unprognostic (6.13e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-4)" 0.2 2.6 2.5 0.2 32.3 0.0 0.1 0.0 14.4 2.3 0.0 1.4 0.0 3.3 0.0 0.5 1.6 0.3 0.4 9.2 11.9 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 0.5 2.0 0.0 0.1 0.3 0.0 0.5 1.4 0.0 0.0 0.6 0.1 0.9 0.1 0.1 1.4 0.0 0.5 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 32.3 0.0 14.4 9.2 11.9 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 70.5 0.0 0.1 0.3 0.0 0.0 26.4 0.0 0.0 1.6 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.2 5.3 0.7 0.0 0.0 937.7 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.5 0.1 0.0 576.6 0.0 0.0 0.0 0.5 1.9 1.2 0.1 1.8 43.1 0.0 0.1 0.0 254.3 17.3 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.0 1.6 6.6 0.5 4.9 0.2 0.5 0.1 0.4 0.0 0.1 0.1 0.0 0.3 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DNM1 DNM ENSG00000106976 "Dynamin 1" Q05193 9 128191655-128255248 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 319.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.4;Cone photoreceptor cells: 89.6;Excitatory neurons: 176.1;Inhibitory neurons: 182.2;Rod photoreceptor cells: 78.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 319.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 126.9;U-87 MG: 46.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005920, HPA049910" Enhanced NA NA 8800 "Cluster 10: Brain - Neuronal signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB005920: , HPA049910: AB_2680948" "unprognostic (3.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.34e-3)" "unprognostic (3.95e-2)" "unprognostic (4.57e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-3)" "unprognostic (1.20e-1)" "unprognostic (5.53e-2)" "unprognostic (6.53e-2)" "unprognostic (6.62e-3)" "unprognostic (6.30e-1)" "unprognostic (9.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (3.07e-3)" "unprognostic (1.10e-3)" 22.2 7.9 99.8 3.7 129.1 2.0 13.2 13.6 319.5 30.8 0.0 8.0 1.9 8.8 2.4 5.5 9.4 13.4 7.8 140.1 15.9 14.1 5.3 4.6 2.4 50.7 4.1 2.5 8.4 4.1 33.6 2.5 36.6 9.0 2.7 68.3 9.0 3.0 3.2 15.0 9.0 5.3 0.0 1.0 5.0 4.9 10.0 0.9 5.2 4.0 1.8 10.6 21.6 123.1 8.7 126.9 11.3 2.8 3.6 36.8 0.6 8.0 18.9 15.7 6.5 1.7 2.6 0.2 10.7 16.7 0.6 15.3 1.8 0.8 8.6 0.1 12.1 8.3 19.5 0.5 2.6 1.1 5.6 9.8 0.2 12.4 0.2 15.2 0.0 7.3 3.1 0.5 0.0 3.6 0.7 2.7 12.2 2.2 23.1 15.6 0.4 3.9 2.4 0.0 16.1 27.1 27.1 0.8 1.2 1.4 0.3 11.2 0.6 0.5 34.8 36.2 16.6 1.0 0.4 0.8 46.8 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 99.8 129.1 13.6 319.5 140.1 15.9 50.7 4.1 36.6 0.0 10.0 123.1 2.2 0.0 0.0 18.9 0.9 7.9 1.7 0.3 8.0 112.4 2.9 3.9 2.0 5.7 0.8 0.0 89.6 0.3 0.2 0.4 1.9 0.8 0.9 1.3 19.0 1.8 0.0 0.0 176.1 0.9 0.4 24.3 2.6 1.4 1.3 2.8 0.7 0.6 10.6 50.5 182.2 0.9 0.0 0.6 10.5 1.0 2.8 9.2 3.6 22.5 1.3 10.7 0.0 33.7 14.3 0.6 5.0 1.5 0.7 0.8 2.5 5.3 1.1 78.4 0.0 2.1 3.8 1.0 1.8 2.5 7.5 0.8 1.6 2.1 1.6 0.8 DNM3 KIAA0820 ENSG00000197959 "Dynamin 3" Q9UQ16 1 171841498-172418466 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Hydrolase, Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 66.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 365.7;Inhibitory neurons: 631.8;Oligodendrocyte precursor cells: 976.1;Oligodendrocytes: 1970.9" "Cancer enhanced" "Detected in many" "glioma: 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 22.9;HMC-1: 10.2;RPTEC TERT1: 19.0;U-251 MG: 14.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064121 Approved "Golgi apparatus" NA NA 70000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA064121: AB_2685193" "unprognostic (8.21e-2)" "unprognostic (6.80e-3)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (8.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.52e-3)" "unprognostic (6.46e-2)" "unprognostic (5.52e-2)" "unprognostic (2.96e-2)" "unprognostic (2.45e-2)" "unprognostic (3.37e-1)" "unprognostic (6.10e-4)" "unprognostic (1.60e-3)" "unprognostic (1.35e-1)" "unprognostic (2.22e-1)" "unprognostic (2.70e-3)" 4.2 11.9 15.3 1.0 29.9 1.3 4.0 59.4 24.3 5.8 0.0 2.4 0.6 3.2 1.3 1.3 3.2 2.7 2.1 12.2 36.0 4.1 0.4 4.4 1.1 42.8 29.5 2.6 1.1 1.2 6.2 0.4 47.8 2.6 1.1 13.4 2.1 1.6 1.2 2.4 1.4 3.1 10.6 1.8 2.7 3.2 32.3 1.8 3.3 1.3 0.8 2.2 5.1 66.9 0.8 2.5 2.0 0.4 1.5 1.0 0.0 0.5 1.2 1.0 1.3 0.0 3.7 0.0 7.5 1.1 1.2 0.3 1.5 2.9 0.9 1.0 2.9 22.9 3.7 0.0 0.1 0.5 10.2 0.7 0.5 1.2 0.7 1.1 0.5 2.0 0.0 0.3 0.4 0.0 1.5 0.1 5.8 9.5 1.7 1.5 9.9 0.0 19.0 0.1 3.9 0.8 2.7 0.7 0.2 0.7 0.0 0.9 0.3 2.8 3.8 2.3 14.3 3.8 0.7 0.2 2.7 1.2 1.0 0.0 0.1 0.0 0.2 0.0 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.5 0.3 0.3 0.1 0.0 1.4 1.2 15.3 29.9 59.4 24.3 12.2 36.0 42.8 29.5 47.8 10.6 32.3 66.9 21.8 0.0 6.8 207.3 1.5 2.4 1.5 0.7 3.4 25.1 1.4 1.3 2.4 0.0 0.4 0.0 29.2 0.1 0.7 0.2 3.9 0.3 8.2 7.3 1.3 19.5 0.0 0.8 365.7 0.4 0.1 3.2 7.1 1.0 1.3 0.8 8.2 0.2 0.7 8.4 631.8 0.7 0.0 0.6 3.1 3.9 1.8 13.4 0.0 178.0 0.3 5.9 0.0 976.1 1970.9 2.5 0.1 2.6 0.3 0.7 0.0 0.8 2.2 29.0 0.0 4.5 2.2 5.3 0.4 1.1 1.7 0.3 0.9 10.3 0.8 0.7 DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 230.4;Excitatory neurons: 236.8;Inhibitory neurons: 259.1;Oligodendrocyte precursor cells: 178.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.5;Hep G2: 11.1;RPMI-8226: 10.5;SCLC-21H: 4.7;SH-SY5Y: 10.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" 1.1 0.7 8.8 0.7 10.3 0.1 0.5 0.9 14.0 1.8 0.0 0.6 0.3 1.5 0.5 0.7 0.7 3.2 6.2 17.8 10.6 4.9 2.4 2.4 0.5 10.9 11.6 2.2 0.2 12.5 0.7 5.9 9.7 1.3 0.5 22.3 0.8 2.1 0.1 0.5 0.5 2.5 4.1 0.9 0.7 1.5 6.5 0.1 2.2 0.6 0.5 3.1 1.1 5.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.0 11.1 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 10.5 0.0 0.0 4.7 10.5 0.0 0.0 0.0 7.6 0.0 0.0 0.0 4.0 0.6 0.0 1.5 0.3 0.0 0.0 3.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.3 0.9 14.0 17.8 10.6 10.9 11.6 9.7 4.1 6.5 5.8 0.5 0.0 0.0 9.8 0.0 0.3 0.1 0.0 0.0 230.4 0.1 0.0 9.1 0.0 1.3 0.0 14.6 0.0 1.2 0.0 1.9 0.0 45.3 0.4 13.3 1.5 0.0 0.0 236.8 0.0 0.0 6.7 0.0 0.3 0.0 17.2 0.0 0.9 0.0 10.1 259.1 0.0 0.0 0.3 0.8 30.6 1.5 2.1 0.0 8.4 0.1 6.9 2.1 178.4 6.4 0.0 0.0 6.8 0.7 0.1 0.0 9.6 0.0 14.6 0.0 0.4 5.5 0.9 1.1 0.1 0.6 0.0 1.2 4.9 0.0 0.1 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPYD DPD ENSG00000188641 "Dihydropyrimidine dehydrogenase" Q12882 1 97077743-97995000 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.5" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1712.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033241, HPA045210" Uncertain NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB033241: AB_2094323, HPA045210: AB_2679256" "unprognostic (2.33e-2)" "unprognostic (1.69e-1)" "unprognostic (9.82e-3)" "unprognostic (1.04e-1)" "unprognostic (1.13e-2)" "unprognostic (8.81e-2)" "unprognostic (2.86e-1)" "unprognostic (3.05e-1)" "unprognostic (1.56e-1)" "unprognostic (9.29e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (1.43e-1)" "unprognostic (3.43e-2)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" 22.2 13.2 7.2 22.6 12.8 10.3 16.7 5.7 10.4 18.8 2.4 11.9 21.9 14.9 8.4 17.1 14.3 25.7 8.9 7.4 12.9 12.6 68.5 29.6 16.6 12.4 9.4 24.0 11.8 9.2 6.2 4.5 12.1 9.9 10.1 3.3 15.0 13.4 5.8 7.1 19.4 18.2 6.9 24.7 8.4 3.7 12.9 17.0 10.3 10.1 12.0 18.2 14.2 24.4 22.2 6.2 7.8 0.2 42.4 72.5 0.1 35.2 31.9 32.1 23.6 0.0 9.2 11.7 50.6 32.9 5.1 5.2 0.0 8.3 58.7 11.6 7.3 10.0 11.1 0.2 18.8 4.5 0.6 57.5 3.0 25.7 29.3 67.7 26.8 6.8 0.4 36.4 17.0 0.0 23.6 6.4 0.9 0.2 7.5 0.1 37.1 18.6 39.4 0.1 11.1 8.8 30.1 2.5 0.3 0.8 0.0 10.2 30.9 69.2 5.0 56.4 70.6 3.0 0.1 0.2 10.2 12.6 56.2 18.2 61.1 4.1 11.6 29.5 14.8 2.2 13.3 11.0 32.7 4.9 12.5 11.1 59.8 13.3 27.1 0.9 15.8 21.9 7.2 12.8 5.7 10.4 7.4 12.9 12.4 9.4 12.1 6.9 12.9 24.4 25.5 16.0 39.1 23.8 15.4 7.6 8.8 9.4 18.8 2.5 8.4 8.3 5.3 40.0 11.5 7.3 0.0 0.2 19.2 3.3 5.9 2.5 7.0 1.5 15.2 14.7 3.0 13.3 258.6 6.4 0.2 30.0 10.7 1.7 9.5 4.5 17.2 54.2 17.1 0.0 30.5 5.5 6.1 130.4 27.0 4.0 33.5 73.7 3.6 105.9 98.1 4.8 27.8 34.2 1712.3 5.3 2.1 18.8 17.0 4.9 21.0 6.6 8.6 0.1 13.1 16.0 17.7 1.2 3.1 19.7 5.5 0.1 31.4 5.1 6.8 9.3 DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 101.5;Cone photoreceptor cells: 331.5;Granulosa cells: 261.9;Peritubular cells: 205.7;Rod photoreceptor cells: 125.0" "Cancer enhanced" "Detected in all" "glioma: 109.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 685.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 740000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA010948: AB_1847245" "unprognostic (3.92e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-3)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (5.99e-2)" "unprognostic (6.92e-2)" "unprognostic (4.72e-2)" "unprognostic (2.08e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.87e-9)" "unprognostic (1.14e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.23e-4)" 58.4 18.6 63.4 54.4 68.6 0.8 37.5 60.3 55.8 66.1 30.4 142.1 18.4 119.9 73.9 69.0 63.4 65.1 59.2 57.0 116.0 7.7 4.4 45.2 18.1 123.7 94.2 88.0 5.5 2.7 12.7 19.8 81.8 104.6 37.6 163.8 24.5 162.0 68.7 23.8 43.3 217.6 115.2 26.4 40.9 19.9 95.2 7.1 22.4 36.0 27.0 118.0 50.6 105.1 0.5 36.1 63.9 0.1 2.3 63.3 1.6 34.1 163.0 71.4 94.4 114.5 3.1 0.0 9.6 100.1 37.4 3.7 13.1 1.4 79.1 16.3 29.2 0.1 30.0 0.2 63.1 0.3 0.2 12.2 0.6 153.8 60.3 178.7 206.9 0.0 0.0 1.3 41.1 0.3 0.2 0.6 135.9 0.2 53.7 0.2 135.1 0.5 63.0 14.2 47.1 685.4 0.3 0.3 10.8 87.9 0.5 1.0 91.1 51.6 38.5 127.0 127.3 113.9 21.7 0.2 47.5 1.4 27.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 63.4 68.6 60.3 55.8 57.0 116.0 123.7 94.2 81.8 115.2 95.2 105.1 59.9 0.0 2.8 101.5 0.0 9.4 3.4 1.5 2.2 14.2 8.1 6.6 7.8 1.5 4.0 0.0 331.5 0.1 0.0 0.2 0.0 9.1 16.8 0.3 4.6 62.6 6.6 0.0 11.3 8.4 0.3 79.8 3.1 1.2 1.3 261.9 57.8 0.4 1.6 5.0 12.9 0.2 24.4 1.2 11.9 19.2 42.9 3.1 19.6 5.6 0.0 28.3 0.0 83.9 0.7 13.7 0.0 205.7 0.3 10.1 0.0 0.1 2.8 125.0 0.0 23.6 40.9 1.8 3.2 3.7 8.2 0.4 1.5 49.6 0.3 4.5 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 484.1;esophagus: 1370.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 113.3;Fibroblasts: 118.6;Melanocytes: 74.7;Pancreatic endocrine cells: 70.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 402.1;BJ hTERT+: 293.1;fHDF/TERT166: 279.6;hTEC/SVTERT24-B: 195.6;LHCN-M2: 215.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" NA NA 8700000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" 49.3 15.4 7.6 11.8 8.5 0.8 27.1 7.3 14.7 293.8 6.1 17.7 9.4 51.2 484.1 1370.5 20.1 76.5 81.3 8.1 8.3 15.9 61.2 26.3 1.2 17.4 8.9 8.9 4.1 3.5 12.7 44.6 15.4 15.5 18.1 0.9 223.9 14.0 7.0 70.0 12.4 32.6 8.9 11.5 12.4 2.7 9.4 1.3 11.1 7.8 135.0 24.4 360.1 10.7 35.4 3.5 12.6 0.2 73.9 402.1 11.4 126.9 293.1 76.2 99.5 1.9 19.1 0.6 1.3 279.6 8.8 71.5 0.2 15.0 79.3 0.6 0.7 5.7 4.1 0.7 20.4 0.3 125.5 35.7 0.9 195.6 7.2 112.8 21.3 0.7 27.7 0.8 215.2 0.1 0.4 4.2 1.4 147.8 4.1 2.0 92.7 0.5 2.8 0.1 0.8 0.4 28.8 0.9 106.4 5.8 0.3 34.0 5.8 159.3 23.9 18.3 27.9 0.5 1.1 1.5 84.6 11.7 22.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.6 8.5 7.3 14.7 8.1 8.3 17.4 8.9 15.4 8.9 9.4 10.7 9.1 0.0 1.1 2.9 0.6 14.7 1.9 6.9 0.0 0.7 0.5 0.6 1.8 7.2 7.9 3.7 0.0 2.2 0.6 1.0 0.0 6.2 0.3 3.1 113.3 15.7 0.0 0.0 12.1 4.3 40.9 118.6 7.7 2.5 10.2 1.0 42.5 1.0 17.0 1.7 10.9 1.4 18.3 2.2 22.8 0.3 9.9 10.8 74.7 2.8 0.1 0.5 0.0 1.0 4.4 70.2 1.1 22.2 0.4 1.5 0.1 0.1 0.4 1.2 13.1 4.1 32.3 0.7 0.6 28.1 19.0 10.9 2.1 5.0 0.5 6.9 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 121.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 120.9;Early spermatids: 50.7;Late spermatids: 49.1;Leydig cells: 155.4;Sertoli cells: 85.5;Smooth muscle cells: 70.9" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HBEC3-KT: 12.6;hTERT-HME1: 16.4;HUVEC TERT2: 16.1;LHCN-M2: 37.0;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" 41.7 19.8 2.0 2.8 2.5 0.2 47.1 1.9 2.3 15.6 3.5 6.1 1.9 5.6 6.8 4.0 8.2 4.9 26.2 1.5 2.4 6.9 4.7 2.9 14.2 3.2 4.2 23.7 3.1 4.0 5.8 51.6 3.6 14.2 3.2 66.7 6.9 20.6 72.0 5.9 4.7 6.7 1.6 9.8 3.4 15.0 3.6 20.4 9.0 121.2 9.1 7.7 13.0 2.5 3.2 0.0 6.5 0.2 0.8 0.2 0.0 2.9 0.0 0.5 0.1 0.0 0.0 0.1 10.2 0.1 0.1 0.0 0.0 12.6 0.0 0.0 1.6 0.0 6.1 0.0 2.8 0.0 0.1 5.4 0.0 0.1 16.4 0.0 16.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.3 3.9 0.0 3.7 0.1 1.3 0.0 0.2 0.0 0.1 15.6 0.6 0.2 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.9 2.3 1.5 2.4 3.2 4.2 3.6 1.6 3.6 2.5 11.4 0.0 0.0 0.3 0.0 2.7 0.3 0.0 0.0 1.3 2.4 9.8 2.6 0.0 0.0 0.0 120.9 0.3 0.4 0.0 3.9 0.5 50.7 0.2 3.2 5.4 0.0 0.0 0.6 1.0 0.5 17.8 0.0 0.3 0.0 1.6 1.4 0.0 0.7 0.0 0.9 0.0 0.0 0.0 4.2 49.1 155.4 0.6 5.4 1.9 0.0 3.4 0.0 1.0 0.1 1.3 0.0 30.9 0.0 0.2 0.0 6.5 0.0 33.1 85.5 22.0 70.9 9.8 3.3 0.3 2.0 0.5 0.4 23.5 0.0 0.3 EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 203.4;Early spermatids: 220.3;Excitatory neurons: 262.3;Inhibitory neurons: 245.4;Late spermatids: 495.6;Oligodendrocyte precursor cells: 226.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" 30.0 17.2 15.1 10.7 16.3 6.4 17.4 27.7 19.3 29.0 11.7 41.9 9.7 31.1 7.9 29.5 21.3 20.4 11.7 20.0 16.5 17.1 53.9 11.6 8.8 13.3 22.1 48.0 15.9 15.2 12.2 11.9 14.1 16.0 14.2 20.9 15.7 18.6 8.0 13.0 14.9 30.0 10.9 8.1 17.5 37.4 22.6 13.4 14.4 13.1 10.2 18.1 21.6 16.2 49.7 66.9 26.8 16.4 46.1 89.0 27.2 43.6 42.4 31.6 25.9 80.4 36.2 34.2 15.4 79.8 47.5 29.1 35.1 30.5 51.9 36.3 16.5 29.7 22.9 95.2 31.5 17.5 21.5 40.9 54.1 31.6 61.9 31.3 20.5 26.7 20.6 19.1 51.1 19.4 20.0 10.9 26.3 40.8 26.2 17.8 33.8 14.9 20.8 16.1 29.6 23.6 35.1 25.9 43.0 28.5 12.6 17.0 15.2 33.3 34.4 55.8 23.0 21.5 16.2 32.7 33.3 26.3 69.4 0.2 2.2 2.5 4.1 2.4 4.0 6.3 4.2 3.9 3.7 4.9 4.2 3.6 0.8 3.4 1.3 2.4 2.5 2.2 15.1 16.3 27.7 19.3 20.0 16.5 13.3 22.1 14.1 10.9 22.6 16.2 29.0 38.5 18.8 203.4 10.4 15.6 12.0 27.1 43.3 39.7 10.5 12.8 15.2 22.8 20.7 14.7 4.2 10.9 9.9 5.3 15.6 22.1 220.3 10.3 45.4 19.9 16.2 8.8 262.3 40.5 30.1 36.6 9.2 12.1 2.5 15.2 30.0 59.6 5.0 18.5 245.4 5.4 6.1 8.6 11.4 495.6 58.4 7.6 10.6 119.0 6.5 20.1 13.4 226.7 98.7 41.7 5.0 40.3 9.6 13.9 11.4 15.1 14.5 17.8 6.6 33.1 19.4 53.7 31.1 55.4 14.2 2.9 12.7 18.2 8.1 13.1 EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Adipocytes: 409.0;Endothelial cells: 261.7;Hepatic stellate cells: 175.3;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" NA NA 470000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" 46.3 20.2 6.7 9.6 7.1 0.2 38.2 7.1 11.2 37.1 7.8 10.3 6.8 27.9 9.9 12.7 19.2 31.4 38.5 6.3 7.5 79.7 7.5 48.4 6.6 8.1 7.0 6.9 6.2 19.2 9.6 0.8 9.0 12.7 8.1 1.5 9.2 25.6 18.5 9.0 8.3 38.8 7.0 3.5 8.2 2.3 9.4 8.7 43.6 40.2 4.9 24.9 13.9 7.4 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 30.6 0.0 0.0 0.1 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 7.1 7.1 11.2 6.3 7.5 8.1 7.0 9.0 7.0 9.4 7.4 409.0 6.4 6.0 0.3 14.0 16.6 0.5 0.1 6.2 0.1 2.1 3.0 14.1 0.0 0.7 0.0 0.0 0.1 1.7 0.0 0.0 0.1 0.7 0.6 0.6 261.7 0.0 8.0 1.3 0.0 0.0 16.2 0.0 0.3 0.0 0.1 175.3 1.1 0.2 0.0 0.2 0.0 0.0 5.5 21.4 1.3 1.2 1.7 16.0 111.5 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 2.6 1.0 0.0 0.2 0.0 0.4 0.0 5.8 21.4 0.2 0.5 1.1 14.6 0.3 2.4 0.7 0.0 1.0 EML1 "ELP79, EMAP, EMAPL, HuEMAP" ENSG00000066629 "EMAP like 1" O00423 14 99737693-99942060 "Disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Lissencephaly, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.4;Excitatory neurons: 57.5;Late spermatids: 61.3;Microglial cells: 69.3;Oligodendrocytes: 61.8;Rod photoreceptor cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.3;HDLM-2: 89.5;U-2197: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033137, HPA049105" Uncertain NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB033137: AB_2098052, HPA049105: AB_2680633" "unprognostic (9.86e-3)" "unprognostic (2.54e-1)" "unprognostic (8.18e-2)" "unprognostic (2.77e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (2.68e-2)" "unprognostic (8.09e-3)" "unprognostic (7.83e-2)" "unprognostic (3.06e-3)" "unprognostic (1.89e-2)" "unprognostic (9.98e-2)" "unprognostic (4.09e-3)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.81e-3)" "unprognostic (7.03e-3)" 15.5 6.4 8.6 9.1 25.5 0.3 9.7 7.3 12.7 13.2 15.0 35.5 6.8 16.1 10.8 24.1 15.1 18.6 17.2 8.6 7.9 8.6 5.5 13.2 3.3 9.2 9.0 3.8 8.7 28.3 9.2 27.2 10.7 9.6 14.9 50.1 5.0 16.9 47.5 9.4 10.1 31.0 9.4 3.9 14.9 8.0 8.9 1.3 14.8 34.4 4.4 17.1 10.3 22.8 0.0 44.9 36.8 12.9 20.1 39.5 0.3 35.9 67.3 25.2 8.4 5.1 0.9 0.0 22.2 22.6 30.3 0.2 26.7 3.1 11.5 89.5 13.6 0.0 7.9 0.8 4.8 0.1 0.9 11.6 4.9 31.0 11.7 16.0 44.5 0.7 0.1 0.0 10.4 21.3 0.1 0.1 14.5 0.1 17.2 5.4 13.5 0.2 56.2 0.6 14.1 20.9 11.8 1.8 0.0 24.1 13.7 1.2 42.3 22.8 4.1 104.3 14.9 0.5 0.0 0.3 57.3 0.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 25.5 7.3 12.7 8.6 7.9 9.2 9.0 10.7 9.4 8.9 22.8 22.8 16.0 7.0 17.3 0.3 2.8 1.2 0.4 1.2 9.2 1.0 1.3 15.0 1.5 4.5 3.7 158.4 2.7 0.1 0.1 0.0 4.6 29.1 15.9 14.2 30.1 0.0 0.0 57.5 4.9 0.6 20.6 4.1 4.7 0.0 1.6 40.0 1.3 1.3 1.7 29.9 0.6 0.0 2.5 4.7 61.3 7.2 1.9 7.2 69.3 0.6 8.8 1.0 17.6 61.8 0.8 0.0 6.0 1.2 1.4 0.0 2.5 11.8 113.6 0.0 20.8 8.7 4.8 11.3 0.4 4.0 2.9 0.7 1.2 0.0 0.7 ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213518-43786908 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Astrocytes: 173.3;Early spermatids: 190.8;Excitatory neurons: 452.3;Inhibitory neurons: 692.0;Late spermatids: 264.8;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 771.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 17.3;RH-30: 24.1;TIME: 17.8;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" 3.4 1.0 7.8 2.5 12.5 0.3 1.8 4.6 9.2 3.3 0.4 8.5 0.6 5.0 0.9 1.0 2.7 1.6 4.7 7.7 7.9 3.5 0.4 0.9 2.2 10.0 6.9 6.4 1.3 0.7 1.9 4.4 10.3 3.0 1.5 2.0 0.4 3.7 8.1 0.5 1.4 4.2 7.4 0.7 2.3 9.0 8.9 2.8 0.4 0.7 1.4 3.1 2.1 14.1 0.2 0.3 3.4 0.0 3.4 13.2 0.7 1.6 3.8 5.7 5.4 2.4 0.4 0.0 0.2 5.1 0.6 0.1 0.7 0.4 2.5 4.2 5.6 0.7 4.0 0.1 2.1 0.1 0.9 12.7 1.2 17.3 8.7 0.9 0.4 2.8 0.0 0.8 3.5 0.3 5.9 0.2 3.8 0.1 1.5 0.0 24.1 0.0 3.0 0.7 11.8 4.5 2.1 3.5 0.9 2.6 0.7 0.1 17.8 1.9 0.6 17.9 1.9 0.0 0.1 0.1 8.3 0.0 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 12.5 4.6 9.2 7.7 7.9 10.0 6.9 10.3 7.4 8.9 14.1 1.5 3.2 0.0 173.3 0.0 0.6 1.3 0.0 2.2 4.3 1.2 0.6 3.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 5.9 0.6 190.8 0.1 1.9 0.4 0.0 0.0 452.3 0.4 0.0 2.5 0.0 0.1 0.0 2.3 0.0 0.0 0.2 1.7 692.0 0.0 0.0 0.0 1.8 264.8 12.2 0.4 0.0 15.0 0.0 0.3 0.0 167.9 771.1 0.1 0.0 4.5 0.0 2.7 0.0 1.1 5.3 0.4 6.6 6.1 5.1 3.8 7.3 0.3 0.3 0.3 0.1 12.3 0.0 0.5 ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.1;intestine: 44.5" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 160.0;Glandular and luminal cells: 387.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Group enriched" "Detected in some" 18 "HEL: 4.4;Hep G2: 14.6;HMC-1: 6.2" "Low region specificity" "Detected in some" "Region enriched" "Detected in single" 4 "spinal cord: 2.6" HPA043772 Enhanced "Secreted - unknown location" NA NA 1100000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" 1.2 6.2 0.4 1.1 0.4 0.1 6.6 0.9 0.5 32.1 0.2 9.3 16.2 3.8 1.2 0.5 2.3 1.3 0.1 0.3 0.5 10.0 5.0 0.9 0.5 0.5 0.6 0.5 0.1 0.3 0.1 0.1 0.5 2.4 8.4 0.3 18.1 15.6 0.1 0.6 44.5 0.8 0.4 0.3 0.5 0.8 0.5 9.6 0.3 0.2 0.4 0.4 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.4 0.0 14.6 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.4 0.9 0.5 0.3 0.5 0.5 0.6 0.5 0.4 0.5 0.4 0.4 0.0 1.1 5.2 0.2 0.0 2.6 0.7 1.2 0.2 1.0 0.6 0.3 0.0 2.5 0.0 0.0 0.0 0.2 9.2 1.9 0.0 1.6 160.0 46.3 1.4 0.0 2.1 2.1 0.0 0.1 0.5 0.0 387.2 36.0 0.1 0.7 1.7 0.1 0.0 4.1 1.5 0.0 0.6 1.1 0.4 1.2 1.5 1.8 2.8 0.0 0.1 1.0 3.5 0.9 0.0 1.9 0.7 0.3 2.7 53.3 9.1 5.4 0.1 0.0 0.2 1.0 2.5 0.8 0.0 0.6 0.1 2.2 0.1 4.9 1.1 ENTPD1 "ATPDase, CD39, NTPDase-1, SPG64" ENSG00000138185 "Ectonucleoside triphosphate diphosphohydrolase 1" P49961 10 95711779-95877266 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Kupffer cells: 110.4;Langerhans cells: 161.3;Microglial cells: 217.4;monocytes: 112.2;Plasma cells: 80.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 17.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 102.2" "Group enriched" "Detected in all" 4 "dendritic cells: 31.9;granulocytes: 102.2;monocytes: 41.0" "Group enriched" "Detected in many" 7 "HDLM-2: 147.5;Karpas-707: 135.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002494, HPA014067, CAB079986" Enhanced Uncertain Microtubules NA NA 19000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Microtubules "CAB002494: AB_563557, CAB079986: , HPA014067: AB_1848178" "unprognostic (1.14e-1)" "unprognostic (1.01e-2)" "unprognostic (3.11e-1)" "unprognostic (5.67e-2)" "unprognostic (9.68e-3)" "unprognostic (3.45e-3)" "unprognostic (6.31e-2)" "unprognostic (5.26e-3)" "unprognostic (2.73e-1)" "unprognostic (1.28e-2)" "unprognostic (6.40e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.33e-5)" "unprognostic (9.79e-2)" "unprognostic (2.30e-1)" "prognostic favorable (7.89e-4)" "unprognostic (5.09e-2)" 11.8 8.3 5.9 24.7 5.5 27.5 10.8 5.0 6.3 17.5 5.0 14.3 9.3 28.0 19.3 19.2 14.0 27.7 8.5 5.3 6.3 7.6 5.4 16.1 20.2 7.1 6.5 5.5 2.8 3.4 3.9 11.4 7.7 11.2 12.8 6.8 6.0 18.1 4.0 6.3 11.7 49.7 6.2 21.5 7.3 4.5 7.5 6.8 20.0 8.7 25.6 30.6 11.0 6.3 1.4 2.7 5.4 7.1 0.1 0.1 5.0 4.5 1.2 0.0 0.0 4.0 1.6 8.2 3.1 0.0 5.3 2.2 0.0 0.0 0.0 147.5 5.2 7.2 4.0 4.3 0.0 12.5 4.1 0.1 0.0 0.6 0.0 2.4 18.2 2.0 5.3 135.4 0.1 4.4 4.7 5.8 5.9 3.6 2.8 15.3 2.4 4.4 1.7 2.2 5.1 6.2 3.6 3.7 3.9 3.6 5.5 5.9 3.9 3.9 2.8 3.8 5.3 21.6 7.2 0.6 4.3 13.9 2.7 0.7 41.0 102.2 0.6 27.2 1.1 13.7 1.6 1.1 31.9 11.4 0.6 0.6 49.4 1.5 6.7 2.1 13.1 15.5 5.9 5.5 5.0 6.3 5.3 6.3 7.1 6.5 7.7 6.2 7.5 6.3 19.6 0.0 1.1 74.1 40.9 8.9 0.3 0.0 0.6 1.4 0.8 1.5 10.1 0.0 0.7 1.8 2.1 0.6 3.7 0.3 1.9 0.0 10.3 0.6 3.6 60.6 0.0 4.4 2.8 2.0 1.9 15.7 6.1 0.6 3.8 0.3 31.4 0.8 26.6 0.0 5.2 0.1 0.0 110.4 161.3 7.3 0.6 62.1 16.0 217.4 112.2 0.4 0.0 20.6 5.0 0.2 1.2 3.0 80.1 0.5 0.1 0.3 0.8 0.8 6.6 1.0 22.7 10.1 4.4 0.8 11.2 15.7 26.9 15.1 1.0 0.5 ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048107-137054061 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.7" "Cell type enhanced" "Detected in many" "Leydig cells: 192.3;Paneth cells: 35.5;Peritubular cells: 96.7;Proximal enterocytes: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 24.3;hTCEpi: 12.7;MCF7: 16.7;OE19: 26.6;SK-BR-3: 21.6;T-47d: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "HPA017676: AB_1848179" "unprognostic (1.64e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (2.15e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.71e-2)" "unprognostic (4.97e-2)" "unprognostic (3.23e-1)" "unprognostic (2.99e-1)" "unprognostic (1.89e-1)" "prognostic favorable (3.51e-6)" "prognostic favorable (1.38e-4)" "unprognostic (2.51e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-3)" 1.0 0.8 17.5 0.9 13.0 0.2 5.0 13.3 14.8 5.9 4.3 6.8 12.2 1.8 1.6 3.3 6.1 4.5 3.4 12.5 28.1 4.7 0.9 0.4 0.1 15.9 31.7 0.7 1.8 0.9 3.0 0.7 17.1 7.3 3.8 1.0 5.5 1.6 2.0 10.2 7.8 1.0 16.7 0.1 6.1 3.5 26.4 0.2 0.6 3.4 0.3 1.2 3.6 14.5 6.5 1.7 0.0 0.1 0.1 0.0 3.9 0.0 0.0 0.0 0.0 1.2 1.9 0.0 1.4 0.0 0.0 5.1 0.5 3.7 0.0 0.0 0.2 0.0 0.8 24.3 0.0 0.0 0.3 0.0 12.7 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 26.6 3.6 0.0 1.1 2.5 2.8 0.6 3.5 0.1 0.3 21.6 0.0 0.1 23.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.5 13.0 13.3 14.8 12.5 28.1 15.9 31.7 17.1 16.7 26.4 14.5 1.1 0.0 0.0 19.2 0.5 1.7 1.9 2.8 4.0 0.2 8.0 13.2 0.5 11.5 1.8 0.0 0.0 0.3 0.0 26.2 0.0 6.2 1.4 12.1 1.5 1.2 25.2 0.0 0.2 4.3 1.1 1.5 5.1 2.8 0.0 0.0 0.4 1.1 0.2 0.0 0.1 9.4 6.1 0.0 0.0 6.2 192.3 0.3 5.4 1.9 0.6 6.8 0.0 0.5 0.1 6.0 35.5 96.7 0.0 4.4 61.8 8.6 3.2 0.1 0.0 0.4 4.1 1.2 4.4 1.8 1.4 1.0 0.2 0.0 16.0 1.5 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.8;endometrium 1: 110.9;fallopian tube: 64.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 86.6;Endometrial ciliated cells: 77.9;Endometrial stromal cells: 79.9;Glandular and luminal cells: 98.9;Hepatocytes: 52.1;Horizontal cells: 62.2;Skeletal myocytes: 56.7" "Cancer enhanced" "Detected in many" "breast cancer: 40.2;endometrial cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "MCF7: 46.0;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: AB_2665701, HPA000449: AB_1078753, HPA000450: AB_1078754" "unprognostic (8.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.47e-7)" "unprognostic (4.79e-1)" "unprognostic (2.43e-3)" "unprognostic (4.10e-5)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (7.35e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-2)" "unprognostic (7.91e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" 4.2 1.8 3.2 1.5 1.3 0.8 29.1 2.9 1.3 83.8 3.2 0.9 0.4 110.9 1.2 0.5 64.9 1.2 1.8 0.6 6.7 2.8 16.9 2.0 1.6 0.4 0.5 9.0 1.0 0.2 6.6 0.4 0.3 6.1 0.5 3.5 0.9 9.8 5.8 1.1 0.8 50.4 0.2 1.7 0.6 2.3 5.9 1.0 3.4 2.6 2.3 2.1 46.9 0.3 0.6 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.6 0.0 0.0 0.0 1.2 0.1 46.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.2 57.4 0.0 0.1 0.2 0.2 0.5 0.0 5.2 1.1 0.1 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.3 2.9 1.3 0.6 6.7 0.4 0.5 0.3 0.2 5.9 0.3 0.6 0.0 1.1 1.3 2.3 1.0 1.7 0.0 0.0 3.9 86.6 16.4 4.4 0.0 1.0 0.0 8.4 0.1 0.4 0.1 1.9 0.0 40.1 77.9 79.9 2.7 1.8 0.0 4.5 0.2 0.1 11.3 0.0 98.9 2.5 36.9 5.0 52.1 0.9 62.2 5.4 0.0 0.0 4.0 3.1 10.3 4.1 2.5 1.8 1.0 0.2 2.4 0.0 25.1 0.6 0.1 0.0 2.2 8.5 0.6 0.0 3.7 1.3 4.6 0.0 56.7 11.7 1.8 1.3 0.4 1.7 0.1 2.2 4.8 0.1 6.8 F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 160.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.6;Hepatocytes: 195.1;Leydig cells: 215.9;Peritubular cells: 236.2" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 14.4;BJ hTERT+: 11.5;CACO-2: 12.7;fHDF/TERT166: 13.1;Hep G2: 59.6;HHSteC: 11.5;SH-SY5Y: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" NA NA 13000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" 21.3 8.5 1.1 1.5 1.2 0.0 11.7 2.5 2.0 53.8 1.4 5.6 10.9 13.2 16.4 8.9 23.9 10.9 40.7 1.1 1.8 4.1 160.0 14.4 3.2 2.6 1.5 27.9 7.1 0.2 4.5 4.4 2.5 12.8 2.0 0.9 5.1 7.1 6.8 20.7 11.9 2.7 1.3 3.2 8.6 10.1 1.4 1.4 8.3 6.6 1.3 11.9 25.8 1.1 0.1 0.0 2.5 0.4 8.0 8.1 0.1 14.4 11.5 0.8 0.3 12.7 0.1 0.1 0.5 13.1 1.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 59.6 11.5 0.0 0.3 8.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 1.5 0.1 0.0 0.3 0.0 1.3 0.2 0.3 0.1 0.0 0.0 0.2 1.0 27.9 0.1 0.5 0.1 0.6 0.6 0.1 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 2.5 2.0 1.1 1.8 2.6 1.5 2.5 1.3 1.4 1.1 7.0 0.0 0.0 1.3 0.6 15.7 0.1 0.0 0.0 1.1 0.4 0.3 9.1 4.3 0.0 1.8 0.0 0.6 0.0 0.1 0.0 0.1 2.9 1.9 45.9 3.8 17.9 2.7 1.3 0.0 0.4 113.6 6.1 1.0 1.3 2.2 7.9 195.1 1.4 6.7 1.4 5.0 0.0 4.8 25.0 9.6 215.9 1.3 19.6 5.6 0.6 4.5 0.0 0.5 0.1 0.3 6.5 236.2 0.0 0.3 28.3 6.4 0.0 1.2 52.6 14.5 40.9 2.3 1.2 0.5 15.3 1.1 1.9 2.4 2.2 0.4 FAM102B "DKFZp779B126, SYM-3B" ENSG00000162636 "Family with sequence similarity 102 member B" Q5T8I3 1 108560089-108644900 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.9;Langerhans cells: 43.2;Microglial cells: 52.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028451 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nucleoli, Cytosol" "HPA028451: AB_10602497" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" "unprognostic (4.08e-3)" "unprognostic (3.87e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-3)" "unprognostic (3.10e-1)" "unprognostic (2.62e-2)" "unprognostic (1.32e-2)" "unprognostic (2.17e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.47e-6)" "unprognostic (1.06e-1)" "unprognostic (2.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" 9.1 3.9 8.1 10.5 9.7 21.2 10.7 5.1 9.2 7.4 0.1 13.3 11.0 6.5 4.2 6.0 5.1 14.7 6.6 9.4 8.6 3.2 4.9 7.8 9.0 4.1 6.8 5.3 3.8 7.5 3.8 5.9 8.1 6.3 14.6 3.6 13.7 7.8 1.3 3.7 11.2 8.8 3.0 8.8 7.6 8.6 5.6 8.7 3.5 6.0 8.2 16.4 4.4 5.0 6.9 4.9 9.7 5.2 17.0 10.2 6.4 4.0 5.4 6.1 10.3 1.8 6.8 7.6 3.6 10.4 6.3 13.1 33.2 1.4 7.8 5.1 4.8 10.6 35.8 0.8 4.3 14.0 19.8 5.5 1.4 9.0 0.5 12.3 4.0 12.5 26.3 41.2 14.4 28.4 9.0 10.0 7.6 16.2 24.6 20.8 24.5 1.6 1.7 7.9 31.4 9.3 15.9 27.4 8.3 6.8 5.8 22.5 0.7 9.8 18.4 8.6 15.5 7.6 1.9 7.1 14.4 10.8 5.3 2.9 0.4 0.4 0.3 0.9 0.2 0.3 0.3 0.4 1.0 0.3 0.2 0.2 0.3 0.2 0.3 0.2 0.3 0.1 8.1 9.7 5.1 9.2 9.4 8.6 4.1 6.8 8.1 3.0 5.6 5.0 5.9 0.0 2.2 12.1 6.1 6.1 2.3 1.0 4.6 3.9 10.1 7.2 1.9 10.0 2.2 1.8 0.0 2.4 17.2 15.6 1.9 2.7 15.3 2.1 7.8 5.5 7.2 3.8 54.9 6.1 2.7 16.3 6.6 5.2 7.6 3.6 8.2 1.2 9.7 0.0 27.9 8.1 0.0 25.1 43.2 6.9 14.3 27.5 5.4 52.5 15.2 1.2 11.3 25.1 7.2 4.5 10.5 20.7 11.9 1.9 4.5 1.0 1.8 1.1 0.0 3.2 6.5 4.4 6.4 6.5 3.7 3.4 16.4 36.2 13.8 4.6 FAM13C FAM13C1 ENSG00000148541 "Family with sequence similarity 13 member C" Q8NE31 10 59246130-59363181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.0" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 477.1" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 4.1;HSkMC: 5.1;hTERT-RPE1: 3.4;NTERA-2: 4.5;SCLC-21H: 8.6;SH-SY5Y: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037888 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037888: AB_10962981" "unprognostic (3.68e-1)" "unprognostic (6.10e-2)" "unprognostic (2.46e-1)" "unprognostic (6.69e-5)" "unprognostic (8.54e-2)" "unprognostic (4.56e-2)" "unprognostic (3.30e-2)" "unprognostic (1.06e-2)" "unprognostic (6.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.00e-3)" "unprognostic (3.27e-1)" "unprognostic (4.51e-6)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (1.94e-3)" "unprognostic (4.66e-3)" 13.5 16.2 20.8 3.9 45.8 0.0 9.3 33.2 32.4 8.7 3.7 7.7 4.2 8.7 8.0 13.8 14.5 11.5 8.1 21.3 34.3 3.4 2.1 9.9 4.7 49.3 36.3 21.2 2.2 4.7 4.7 2.6 40.9 17.2 6.2 9.9 5.6 7.9 17.1 7.2 5.9 12.2 35.5 5.1 3.8 5.2 37.6 5.2 6.3 22.9 2.3 4.4 7.9 68.0 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 1.3 0.2 0.1 0.0 1.2 0.0 4.1 1.9 0.1 0.0 0.0 5.1 0.6 0.2 0.0 3.4 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 4.5 0.0 0.4 0.0 0.8 0.0 0.0 1.3 8.6 5.0 0.0 0.2 0.0 0.3 0.7 0.0 0.0 2.5 2.2 0.1 2.1 0.0 0.0 0.1 3.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 45.8 33.2 32.4 21.3 34.3 49.3 36.3 40.9 35.5 37.6 68.0 47.8 0.0 0.0 33.6 0.1 4.8 9.3 0.3 8.0 10.5 0.7 2.7 2.5 0.0 0.7 0.0 6.2 0.0 0.4 0.1 7.9 0.0 49.0 18.6 1.5 35.2 0.0 0.0 66.8 0.0 0.0 19.8 0.5 5.3 0.0 26.9 3.9 0.5 0.0 3.3 73.2 0.2 20.3 0.0 2.5 22.1 23.0 0.7 3.6 7.5 0.0 8.8 0.0 56.8 477.1 0.0 0.0 21.1 0.1 5.4 0.0 0.6 20.7 13.6 39.5 23.4 36.2 1.4 0.7 2.4 6.3 0.0 1.2 17.4 0.2 1.1 FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 16.1;heart muscle: 15.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Cardiomyocytes: 6.6;Fibroblasts: 19.7;Hepatic stellate cells: 4.6;Langerhans cells: 9.5;Melanocytes: 7.2;Suprabasal keratinocytes: 4.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-2197: 259.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" 3.1 2.7 0.0 0.5 0.1 0.1 3.4 0.1 0.3 2.6 4.2 1.8 0.8 4.7 0.4 4.0 2.0 16.1 15.9 0.3 0.0 4.1 10.2 2.5 0.1 0.0 0.0 7.9 1.3 0.2 0.1 0.2 0.0 0.6 2.0 0.0 1.2 0.2 0.3 3.4 1.3 4.7 0.0 0.6 1.0 0.4 0.0 0.2 2.7 1.3 0.5 4.4 1.3 0.1 0.0 0.1 0.0 0.0 27.8 28.4 0.0 14.9 56.2 0.3 0.2 0.0 0.0 0.0 0.0 57.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 2.6 0.0 35.6 4.6 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 57.1 0.0 259.7 0.0 0.0 0.1 0.0 1.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.1 0.8 6.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.8 0.0 0.0 0.3 0.0 0.0 19.7 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.5 0.0 2.8 0.1 7.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 1.8 0.0 0.0 0.1 4.8 0.7 0.2 0.0 0.0 0.0 FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 6.5;brain: 5.9;breast: 5.2;choroid plexus: 5.1;skin 1: 6.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.4;Fibroblasts: 20.4;Langerhans cells: 11.9;Melanocytes: 5.4;Peritubular cells: 4.1;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029408 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" 6.5 0.1 0.8 0.0 2.0 0.1 5.2 5.9 1.7 0.4 5.1 0.6 0.0 0.2 0.0 0.1 0.4 0.4 0.7 0.6 0.8 0.0 0.0 0.2 0.0 1.9 1.3 0.1 0.1 0.0 0.2 0.0 1.5 0.0 0.0 0.1 1.1 0.0 1.0 6.3 0.2 0.1 1.3 0.1 0.5 0.5 1.6 0.7 4.3 2.9 0.1 0.4 0.2 2.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.0 5.9 1.7 0.6 0.8 1.9 1.3 1.5 1.3 1.6 2.6 0.8 0.0 0.0 1.0 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 20.4 0.5 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.6 11.9 0.3 2.5 0.3 5.4 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.0 6.3 0.1 0.3 0.0 0.0 0.0 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 976.2;Inhibitory neurons: 295.1;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 766.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" 17.5 22.7 16.9 3.7 19.5 0.0 13.9 16.0 15.9 19.1 15.9 17.2 2.0 26.4 10.3 9.7 15.8 8.4 17.0 15.5 14.2 4.7 2.1 9.6 2.6 19.7 16.5 26.8 1.9 1.0 4.7 6.6 16.1 13.3 5.2 4.3 5.6 19.5 4.0 5.0 6.8 24.6 15.1 5.0 10.2 4.4 18.4 2.4 8.2 5.7 2.1 16.6 13.1 22.3 0.1 1.4 16.1 23.5 13.1 10.0 0.0 14.1 17.0 9.9 10.3 0.0 0.0 0.0 0.0 21.7 10.2 0.0 8.1 5.2 9.8 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 11.8 0.0 8.0 0.7 12.1 23.2 0.0 0.0 6.1 7.5 0.0 0.0 0.0 5.4 0.0 2.6 0.0 11.4 0.1 0.0 0.0 4.7 15.9 0.0 4.9 15.3 14.5 0.0 0.0 22.9 20.6 4.1 11.7 6.3 0.0 0.0 0.0 11.4 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 19.5 16.0 15.9 15.5 14.2 19.7 16.5 16.1 15.1 18.4 22.3 21.4 3.2 1.9 976.2 0.3 2.4 2.7 2.4 2.2 3.2 0.9 1.1 11.8 0.0 1.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 2.0 11.8 16.7 0.0 0.0 3.7 0.0 0.1 15.9 0.0 2.0 1.3 13.1 15.4 0.2 0.8 30.3 295.1 0.0 0.0 0.6 2.7 0.7 30.1 0.5 5.4 146.1 0.0 2.4 0.0 335.8 766.0 0.0 0.0 41.3 1.2 3.1 0.0 1.2 3.8 2.5 6.6 16.1 8.1 1.4 2.1 1.5 1.7 0.0 0.3 20.7 0.0 2.4 FBXO17 "FBG4, Fbx17, FBXO26, FLJ11798, FLJ25205, MGC9379" ENSG00000269190 "F-box protein 17" Q96EF6 19 38941401-38975742 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 67.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 56.7;Hepatocytes: 58.5;Leydig cells: 83.0;Peritubular cells: 74.1;Proximal tubular cells: 70.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 37.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.68e-1)" "unprognostic (2.62e-2)" "unprognostic (6.97e-3)" "prognostic unfavorable (5.67e-4)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (4.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.71e-3)" "unprognostic (1.91e-2)" "unprognostic (1.83e-3)" "prognostic unfavorable (5.91e-4)" "unprognostic (5.34e-2)" "unprognostic (4.06e-4)" "unprognostic (2.77e-3)" 22.9 5.2 5.7 1.7 5.1 0.4 17.5 7.7 5.5 28.1 4.6 18.7 2.1 25.1 5.9 7.3 20.8 4.7 12.8 4.9 4.7 42.8 67.9 10.3 1.5 4.3 4.3 33.6 11.7 4.8 9.1 2.9 4.4 18.5 1.5 3.8 7.1 7.6 3.1 13.9 6.9 9.2 3.9 4.4 10.2 4.4 5.6 0.8 5.5 1.9 1.2 18.1 18.8 4.0 19.7 37.3 0.1 23.4 16.7 11.7 0.5 7.7 7.8 9.8 11.8 17.0 0.3 0.4 6.3 12.6 19.2 5.3 4.2 5.5 8.9 0.1 14.9 0.1 2.8 19.5 10.9 0.2 0.6 10.2 4.6 16.5 7.7 18.9 13.1 0.1 21.5 0.1 10.1 9.8 0.1 0.3 7.9 0.0 0.1 0.0 0.1 0.1 11.8 0.1 0.2 15.3 10.9 0.0 9.1 5.4 9.5 0.3 3.9 24.4 17.8 10.1 10.5 0.3 1.1 0.1 21.7 0.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 5.7 5.1 7.7 5.5 4.9 4.7 4.3 4.3 4.4 3.9 5.6 4.0 5.3 0.0 1.1 15.0 0.2 18.7 11.3 9.9 33.0 4.1 3.0 14.4 3.1 17.2 5.4 14.7 35.5 6.9 0.2 0.1 56.7 6.7 4.1 0.6 29.6 8.1 0.0 0.0 14.5 2.0 5.4 34.1 0.0 0.5 0.0 20.1 14.6 58.5 38.8 5.0 19.2 0.0 8.2 0.8 8.5 3.4 83.0 1.9 19.6 13.1 0.0 10.2 0.0 16.1 2.0 2.0 0.0 74.1 1.2 15.8 0.0 70.3 2.0 13.0 52.6 20.6 19.8 0.7 4.4 10.0 17.5 5.1 0.9 16.1 0.0 4.1 FCGRT "alpha-chain, FCRN" ENSG00000104870 "Fc fragment of IgG receptor and transporter" P55899 19 49506816-49526428 "Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1362.6;Kupffer cells: 877.7;Paneth cells: 883.9;Proximal enterocytes: 1787.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2346.7" "Group enriched" "Detected in all" 17 "dendritic cells: 922.9;granulocytes: 2346.7;monocytes: 1364.4" "Cell line enhanced" "Detected in many" "ASC diff: 153.7;Hep G2: 144.0;OE19: 165.4;THP-1: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" 263.1 127.7 67.7 99.6 73.3 147.3 198.8 68.0 102.5 217.2 111.1 209.6 304.4 143.1 48.8 60.2 155.5 144.6 123.0 66.3 75.1 177.6 401.6 177.5 143.3 74.0 69.5 193.2 129.4 114.5 79.8 137.5 74.3 104.6 149.3 4.8 106.2 94.7 64.4 112.3 299.3 91.6 73.6 318.9 126.6 28.3 78.8 62.9 111.9 77.8 39.1 136.7 132.0 78.2 0.4 37.1 4.3 123.7 153.7 78.2 6.0 32.1 73.4 20.9 22.9 50.5 22.5 0.2 59.4 45.9 10.8 8.5 1.2 1.1 11.7 0.3 45.5 74.2 0.6 144.0 95.8 1.1 14.2 95.1 1.9 17.5 0.2 86.5 81.3 48.0 12.2 10.9 53.7 0.8 0.6 14.3 2.1 165.4 22.0 2.6 35.3 3.7 96.0 9.3 2.6 23.1 5.6 0.2 4.5 18.3 26.5 196.1 28.1 52.8 11.8 0.9 1.3 2.4 13.5 9.8 10.8 70.2 7.9 566.8 1364.4 1011.5 24.7 904.8 29.8 58.0 39.8 39.7 922.9 62.5 89.4 51.0 2346.7 28.6 630.2 536.4 28.2 1276.9 67.7 73.3 68.0 102.5 66.3 75.1 74.0 69.5 74.3 73.6 78.8 78.2 479.6 67.3 89.3 21.2 44.2 126.1 130.4 130.7 52.9 0.7 125.5 151.3 30.7 158.7 79.9 73.5 4.2 12.7 83.8 652.3 60.7 86.3 6.5 29.1 89.6 259.2 158.1 55.8 0.2 61.6 24.9 269.9 108.6 24.8 70.5 181.2 587.6 343.9 1362.6 0.0 0.2 349.0 57.0 877.7 438.1 21.8 362.2 608.6 186.7 24.4 190.6 13.4 11.3 10.1 0.2 90.6 883.9 183.6 63.2 87.9 1787.7 329.5 53.4 5.2 216.9 149.2 105.6 21.1 17.6 27.7 107.1 20.7 32.4 129.9 565.1 115.4 FEZ1 UNC-76 ENSG00000149557 "Fasciculation and elongation protein zeta 1" Q99689 11 125442881-125592568 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 176.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.8;Horizontal cells: 166.5;Oligodendrocytes: 246.6" "Cancer enriched" "Detected in all" 10 "glioma: 68.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 23.4;MAIT T-cell: 15.5" "Lineage enriched" "Detected in many" 23 "T-cells: 23.4" "Cell line enhanced" "Detected in many" "AF22: 48.3;HBEC3-KT: 66.0;NTERA-2: 68.6;SCLC-21H: 54.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038490, HPA076844" Approved Approved Microtubules,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Microtubules, Cytosol" "HPA038490: AB_10672647, HPA076844: " "unprognostic (5.68e-2)" "prognostic unfavorable (9.06e-5)" "unprognostic (7.40e-2)" "unprognostic (3.73e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.72e-1)" "unprognostic (2.06e-1)" "unprognostic (8.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-1)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (2.14e-2)" "unprognostic (2.68e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" 16.9 5.4 96.8 2.9 144.0 0.9 11.3 145.5 120.6 21.8 53.1 39.3 1.7 23.5 2.3 6.2 14.7 6.9 37.4 95.5 120.4 6.8 5.5 34.2 1.9 145.6 136.9 12.7 2.5 1.9 17.6 3.8 138.9 15.4 3.3 18.7 6.4 7.6 5.9 7.9 12.6 8.3 134.8 8.8 15.9 12.7 126.7 0.5 10.2 3.0 1.4 26.5 16.9 176.6 0.3 0.0 48.3 0.2 39.2 25.3 0.0 10.3 14.6 3.8 0.6 0.2 0.3 0.1 16.3 21.1 11.4 0.5 31.2 66.0 2.4 2.3 0.5 37.6 0.1 0.0 25.3 0.0 0.6 23.1 17.6 11.5 29.3 0.4 32.0 0.0 4.5 0.6 3.8 1.5 0.2 0.0 68.6 0.5 1.2 0.0 0.1 0.2 0.0 30.3 54.3 5.5 0.3 0.1 1.4 27.3 4.9 26.4 19.3 0.4 2.4 0.2 11.1 0.6 0.5 0.1 7.9 0.0 26.6 0.2 0.8 0.0 23.4 0.1 15.5 0.1 0.9 5.1 0.4 0.0 0.6 5.5 0.2 1.0 0.0 0.1 0.0 4.4 96.8 144.0 145.5 120.6 95.5 120.4 145.6 136.9 138.9 134.8 126.7 176.6 4.9 0.0 5.2 53.2 0.8 8.0 4.9 96.9 6.2 23.1 0.5 10.3 109.8 2.8 9.6 0.0 2.1 8.0 23.3 0.1 27.4 2.8 68.6 0.8 14.2 13.9 5.4 0.0 41.0 0.4 1.2 43.0 0.5 0.5 0.0 11.1 58.9 1.0 91.6 166.5 48.7 0.0 16.2 24.9 15.5 65.9 25.4 2.3 78.2 12.2 1.9 97.1 74.2 32.2 246.6 0.3 0.0 35.3 0.9 12.7 0.0 2.1 3.8 17.8 19.7 25.4 35.6 28.8 7.7 0.2 5.5 4.2 7.8 5.5 0.1 3.5 FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 295.2;choroid plexus: 125.8" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Cardiomyocytes: 62.4;Muller glia cells: 69.4;Oligodendrocytes: 119.8" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.6;BJ hTERT+: 33.0;BJ hTERT+ SV40 Large T+: 35.9;BJ hTERT+ SV40 Large T+ RasG12V: 45.0;HBF TERT88: 64.3;hTEC/SVTERT24-B: 45.4;LHCN-M2: 30.6;U-2 OS: 33.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" 17.9 3.3 206.3 1.6 259.3 1.1 12.5 213.9 295.2 1.3 125.8 2.4 1.0 3.1 7.9 2.0 1.7 2.5 50.2 183.5 245.5 66.5 1.7 2.8 1.2 236.2 237.7 0.9 0.8 4.3 6.5 2.1 259.9 1.8 1.3 18.8 7.3 2.3 2.2 1.7 1.2 2.5 225.4 6.9 0.8 2.0 244.3 1.5 5.6 7.8 2.0 1.2 1.0 272.8 5.6 0.3 0.3 1.5 1.1 3.3 1.8 44.6 33.0 35.9 45.0 0.2 0.2 1.3 3.1 15.4 2.1 0.7 0.0 3.5 64.3 0.2 0.0 0.0 0.8 0.4 0.6 0.0 0.4 1.6 1.1 45.4 2.7 9.7 0.0 0.2 0.0 1.6 30.6 0.7 0.1 0.9 1.4 0.1 1.4 0.2 1.5 0.6 1.5 0.2 1.1 2.3 0.1 0.9 0.6 8.0 0.0 0.2 1.1 5.8 33.0 0.8 21.3 0.8 0.4 0.3 8.2 0.3 1.6 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.3 0.0 0.1 0.2 0.1 0.0 206.3 259.3 213.9 295.2 183.5 245.5 236.2 237.7 259.9 225.4 244.3 272.8 1.4 0.0 0.0 75.1 0.1 0.4 5.0 5.7 7.4 3.5 1.2 25.4 62.4 0.0 2.1 20.2 16.7 1.1 0.1 0.0 0.0 1.1 0.4 0.0 0.7 4.8 0.0 0.0 13.0 0.0 0.5 4.7 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 14.6 0.0 12.2 0.0 0.0 1.4 0.0 0.2 3.6 29.0 0.0 69.4 0.0 15.1 119.8 0.6 0.0 0.4 0.0 5.3 0.0 0.3 0.1 11.6 6.6 0.5 23.4 0.1 0.1 0.6 0.0 0.8 0.4 0.0 0.0 0.7 FGF14 "FHF4, SCA27" ENSG00000102466 "Fibroblast growth factor 14" Q92915 13 101710804-102402457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Growth factor" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;cervix: 7.3" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1994.2;Inhibitory neurons: 2754.3;Oligodendrocyte precursor cells: 2271.0" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.0;SH-SY5Y: 5.8;U-87 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049828 Approved "Nucleoli fibrillar center" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli fibrillar center" "HPA049828: AB_2680901" "unprognostic (2.12e-1)" "unprognostic (1.57e-1)" "unprognostic (2.83e-2)" "unprognostic (2.27e-2)" "unprognostic (8.55e-2)" "unprognostic (1.28e-1)" "unprognostic (3.33e-1)" "unprognostic (1.81e-2)" "unprognostic (2.06e-1)" "unprognostic (8.22e-2)" "unprognostic (1.22e-1)" "unprognostic (2.45e-1)" "unprognostic (7.80e-3)" "unprognostic (2.20e-3)" "unprognostic (1.65e-1)" "unprognostic (3.86e-2)" "unprognostic (8.48e-2)" 0.5 1.2 3.2 0.0 2.6 0.0 0.3 11.4 5.1 7.3 0.0 0.2 0.1 0.1 0.4 0.5 2.7 0.4 1.5 2.5 7.7 0.1 0.4 1.4 0.0 2.2 1.1 0.1 0.3 0.0 3.3 0.1 2.2 0.1 0.1 1.6 0.3 0.1 0.1 0.4 0.4 0.0 1.6 0.0 0.7 1.0 4.5 0.0 0.2 0.1 0.0 0.2 0.5 2.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 11.4 5.1 2.5 7.7 2.2 1.1 2.2 1.6 4.5 2.1 0.5 3.2 1.5 74.4 0.0 0.5 0.5 0.2 2.2 33.2 0.3 1.8 7.4 2.8 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.3 18.3 4.4 0.4 0.3 19.2 0.0 1994.2 0.0 0.1 9.6 2.0 1.4 0.0 0.1 0.4 2.5 0.1 32.0 2754.3 1.0 6.1 0.0 0.0 35.2 2.5 0.1 1.8 36.5 0.0 5.2 3.1 2271.0 32.3 0.1 0.0 0.0 0.0 0.8 0.0 0.3 53.8 2.7 0.0 1.9 1.9 2.5 5.2 0.3 0.6 0.0 0.2 0.1 0.0 0.1 FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.8" "Cell type enhanced" "Detected in some" "Fibroblasts: 1.5;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 22.5" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.01e-2)" "unprognostic (5.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (1.49e-2)" 0.6 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.3 0.1 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 10.7;retina: 8.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 39.2;Excitatory neurons: 36.7;Horizontal cells: 40.4;Inhibitory neurons: 54.7;Muller glia cells: 138.8" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.4;HEK 293: 1.4;JURKAT: 2.1;RPMI-8226: 2.1;RPTEC TERT1: 3.0;SCLC-21H: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" 2.4 4.0 1.1 0.1 1.4 0.2 0.2 5.8 4.7 1.5 0.2 0.8 0.7 1.6 0.2 0.2 0.4 0.4 2.7 1.3 1.9 10.7 0.0 0.9 0.1 3.7 1.6 1.0 0.5 0.1 2.2 0.1 4.3 0.3 1.2 8.2 0.3 0.5 0.5 0.1 1.8 0.3 1.2 0.1 0.8 0.5 3.0 0.1 0.1 0.5 0.0 1.2 0.8 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.6 2.1 3.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.4 5.8 4.7 1.3 1.9 3.7 1.6 4.3 1.2 3.0 2.1 0.9 9.6 5.6 12.1 1.8 1.7 0.2 0.6 0.0 14.4 0.7 2.7 25.7 0.0 1.3 3.7 0.0 0.1 3.2 1.7 39.2 0.4 9.4 13.1 2.6 1.6 18.6 0.0 36.7 0.0 0.0 3.9 0.0 26.6 0.0 1.2 0.0 0.0 0.1 40.4 54.7 2.7 0.0 0.0 1.6 2.9 0.6 0.5 1.8 1.9 1.6 138.8 3.1 9.5 1.7 0.2 0.5 0.0 1.9 0.1 10.9 1.1 0.0 5.9 0.0 1.0 0.7 6.3 6.2 0.1 1.4 0.3 3.2 0.1 7.5 0.1 FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 162.5" "Group enriched" "Detected in many" 4 "Kupffer cells: 466.3;Langerhans cells: 571.0;Macrophages: 430.3;monocytes: 463.1;Skeletal myocytes: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.5;eosinophil: 226.3;intermediate monocyte: 380.6;myeloid DC: 160.0;neutrophil: 294.7;non-classical monocyte: 379.8" "Group enriched" "Detected in all" 59 "dendritic cells: 160.0;granulocytes: 294.7;monocytes: 380.6" "Cell line enhanced" "Detected in some" "Karpas-707: 2.0;LHCN-M2: 2.9;NB-4: 2.9;RPTEC TERT1: 5.0;THP-1: 2.1;U-937: 5.0;WM-115: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" NA NA 38800000 7800000 "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "HPA021011: AB_1848532, HPA026682: AB_1848533" "unprognostic (9.80e-3)" "unprognostic (4.70e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (5.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" 48.5 24.4 3.3 89.4 2.7 5.8 35.1 5.3 3.5 17.2 6.1 44.9 43.7 17.8 7.6 38.5 22.1 45.4 21.6 2.4 5.4 44.9 43.5 32.7 56.5 7.7 5.9 10.9 8.3 5.2 7.9 21.6 6.7 10.5 57.2 0.8 14.8 11.7 8.8 13.9 69.8 45.7 6.2 162.5 23.5 6.2 3.9 30.1 18.8 24.6 27.5 73.3 7.1 9.8 0.0 0.0 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.9 0.0 0.0 2.9 0.1 0.0 0.0 0.1 0.2 0.3 5.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.0 5.7 2.8 256.5 226.3 3.9 380.6 1.2 4.3 2.5 3.4 160.0 2.0 1.8 3.0 294.7 2.5 379.8 6.2 4.7 174.0 3.3 2.7 5.3 3.5 2.4 5.4 7.7 5.9 6.7 6.2 3.9 9.8 102.0 6.4 12.1 0.0 26.2 38.1 1.1 0.1 3.4 1.1 1.4 3.0 4.4 0.0 5.0 88.3 10.4 1.3 60.3 17.3 5.9 1.9 7.5 2.6 0.7 50.6 0.0 7.0 0.3 0.0 1.4 102.8 2.0 5.0 10.1 0.6 45.3 5.2 36.2 1.7 0.4 0.3 0.0 466.3 571.0 9.4 27.7 430.3 49.8 33.7 463.1 13.6 39.1 0.0 0.9 0.1 10.9 19.5 82.6 1.1 42.5 5.9 2.2 7.4 0.0 166.2 8.2 0.4 0.4 2.1 31.3 3.7 24.1 0.2 0.8 1.5 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.6" "Cell type enhanced" "Detected in many" "Astrocytes: 279.5;Excitatory neurons: 549.6;Inhibitory neurons: 321.3;Leydig cells: 219.0;Microglial cells: 432.8;Oligodendrocyte precursor cells: 212.1" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "basal ganglia: 2.1;cerebral cortex: 8.2;hippocampal formation: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 60.1;HUVEC TERT2: 38.7;TIME: 55.3;U-138 MG: 58.8;U-2197: 43.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" 9.2 4.5 0.8 4.5 2.1 0.1 2.9 0.0 8.2 11.0 2.3 2.7 0.9 6.1 3.0 3.5 6.4 9.1 3.8 4.7 0.0 1.4 1.2 2.3 3.5 0.0 0.0 29.6 21.7 1.3 1.9 1.2 0.0 5.1 3.1 3.1 1.9 3.3 7.3 6.1 1.7 5.2 0.0 3.0 2.2 4.6 0.2 1.2 4.9 3.1 2.6 5.3 4.2 0.0 0.0 0.2 8.9 0.0 7.9 14.5 0.0 9.7 6.3 9.0 8.4 0.0 0.0 0.0 0.0 28.5 0.9 2.0 13.6 18.6 21.8 0.0 7.8 0.0 5.3 0.0 25.2 2.1 0.0 8.0 10.6 7.5 60.1 2.7 38.7 0.0 0.0 0.0 21.8 0.0 0.0 0.0 4.2 0.0 0.2 0.0 10.8 0.0 0.0 0.0 2.1 0.0 2.3 0.0 3.2 11.8 0.0 0.1 55.3 58.8 9.9 43.0 17.8 0.0 0.0 0.0 18.5 0.0 5.8 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 2.1 0.0 8.2 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.9 0.0 1.3 279.5 0.1 21.4 1.7 5.2 6.2 7.0 3.9 4.4 4.0 10.0 0.4 1.8 0.0 0.4 0.1 0.1 0.0 66.2 3.1 2.2 65.1 15.9 0.0 0.0 549.6 42.8 0.2 34.3 0.5 1.6 0.0 39.9 66.0 0.2 2.4 10.1 321.3 0.0 0.0 1.3 6.6 7.7 219.0 1.2 1.8 432.8 0.6 13.2 0.0 212.1 9.0 20.4 0.0 124.8 0.0 1.1 0.0 0.2 1.7 1.4 13.1 3.2 8.5 1.1 0.6 1.0 24.0 0.8 0.8 32.3 0.0 0.2 FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 199.0" "Group enriched" "Detected in many" 7 "Proximal enterocytes: 97.9;Proximal tubular cells: 196.9" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HSkMC: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" 5.1 5.6 0.1 0.5 0.1 0.0 10.0 0.1 0.3 6.3 0.3 0.4 0.1 3.1 0.1 3.5 4.2 5.2 0.7 0.1 0.1 199.0 2.9 1.5 0.4 0.1 0.1 5.0 2.4 1.1 1.8 2.3 0.1 0.4 0.2 0.0 5.4 0.7 0.1 10.4 20.2 4.2 0.1 0.0 0.9 1.6 0.1 7.4 2.3 0.8 10.8 2.5 1.7 0.1 0.0 0.0 0.0 0.0 2.7 1.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 5.0 0.0 0.0 0.3 3.0 3.2 0.5 0.0 12.5 0.0 0.5 1.1 10.0 2.8 0.0 3.7 0.0 0.3 0.0 0.0 13.7 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.1 0.0 0.1 18.7 0.0 0.0 0.0 3.2 0.0 0.3 0.4 0.0 0.1 2.9 0.0 0.0 0.0 1.5 10.8 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 2.6 0.0 0.1 97.9 196.9 0.0 0.0 6.6 0.5 4.7 0.0 0.1 1.4 2.3 0.8 1.0 2.6 1.4 0.1 FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 48.6;liver: 61.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Hepatocytes: 22.1;Oligodendrocytes: 18.5;Proximal enterocytes: 16.5;Proximal tubular cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 5.7;HSkMC: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 3.7 2.6 2.2 1.9 3.1 0.9 4.1 2.8 3.0 3.3 3.1 5.0 5.4 2.7 6.3 2.3 3.5 4.9 5.2 2.1 2.6 48.6 61.3 3.2 2.9 3.1 2.8 3.8 2.4 4.7 1.9 2.3 3.3 3.1 4.8 0.7 2.0 2.2 1.0 3.4 9.2 2.0 2.6 3.1 5.0 1.7 3.1 3.6 3.2 2.1 3.3 2.4 2.9 3.5 0.1 0.1 0.3 0.4 4.1 3.4 0.2 0.8 3.7 1.1 1.2 0.6 5.3 3.7 5.7 0.1 2.0 0.2 0.7 1.0 1.6 1.6 0.8 0.0 0.0 0.0 0.6 0.7 0.8 6.6 2.4 0.4 1.0 0.4 0.2 1.7 0.2 2.3 0.5 0.7 1.6 1.3 0.4 0.9 1.2 0.4 0.4 2.1 2.6 0.0 0.1 0.0 1.2 1.0 2.4 4.1 2.2 1.0 0.1 0.9 0.3 1.0 0.7 2.9 1.0 2.2 1.8 1.1 0.8 0.2 1.0 0.3 0.9 1.6 0.7 1.2 0.8 1.3 0.9 1.8 1.2 0.9 0.1 1.7 1.1 1.2 2.1 0.8 2.2 3.1 2.8 3.0 2.1 2.6 3.1 2.8 3.3 2.6 3.1 3.5 2.2 0.0 2.6 7.2 3.2 2.8 4.6 5.0 2.8 0.0 2.3 2.0 3.7 2.8 3.7 9.2 0.0 2.8 0.6 7.1 29.4 2.3 5.7 3.8 1.7 1.4 1.2 0.0 0.1 1.4 1.2 6.6 8.2 1.7 1.3 1.5 2.9 22.1 3.7 0.0 0.1 3.2 2.0 5.9 1.3 1.3 1.5 2.7 5.4 2.8 1.6 1.8 1.0 0.0 18.5 1.1 0.7 0.4 1.1 0.9 16.5 49.5 7.3 0.0 0.0 1.8 2.1 0.3 0.5 1.9 1.6 1.9 1.7 2.0 2.8 1.8 FOLH1 "FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA" ENSG00000086205 "Folate hydrolase 1" Q04609 11 49145092-49208638 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 266.4;prostate: 76.0" "Cell type enriched" "Detected in some" 8 "Oligodendrocytes: 367.6" "Cancer enriched" "Detected in many" 27 "prostate cancer: 142.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;RPMI-8226: 1.7;SK-BR-3: 1.8;TIME: 1.3;WM-115: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001451, HPA010593" Enhanced NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "CAB001451: AB_563979, HPA010593: AB_1079685" "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.24e-5)" "unprognostic (2.55e-1)" "unprognostic (8.31e-2)" "prognostic favorable (4.25e-4)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.67e-3)" "unprognostic (2.13e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.30e-6)" "unprognostic (4.81e-2)" "unprognostic (7.27e-2)" "unprognostic (4.74e-3)" "unprognostic (4.04e-1)" 1.8 1.1 17.3 0.9 37.3 0.7 4.8 27.1 27.7 1.9 7.9 0.7 266.4 1.7 0.9 1.5 3.5 10.2 0.5 18.3 22.4 13.5 35.5 1.3 0.9 32.7 28.4 1.0 0.3 0.2 0.0 0.3 31.5 76.0 0.5 4.0 52.8 0.6 0.2 1.7 82.9 1.0 24.1 2.4 1.1 0.8 31.1 0.1 1.0 0.2 0.6 1.4 0.3 59.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.1 2.3 0.2 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.1 1.7 0.0 0.0 0.2 0.7 0.0 1.8 0.3 0.2 0.3 0.0 1.3 0.1 0.9 0.2 0.1 0.0 0.2 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 17.3 37.3 27.1 27.7 18.3 22.4 32.7 28.4 31.5 24.1 31.1 59.3 0.5 0.0 0.6 0.0 0.0 0.3 0.7 0.1 0.6 0.0 8.2 7.0 0.3 0.0 1.9 0.0 0.0 0.0 0.5 0.0 7.9 0.0 5.2 2.1 0.5 5.0 0.0 0.0 0.5 0.0 0.0 2.2 0.0 2.8 0.0 0.0 2.9 25.9 0.1 0.0 1.0 1.1 0.0 0.3 0.0 1.4 1.5 0.2 3.6 1.0 0.0 17.4 0.0 0.0 367.6 0.0 1.2 0.4 0.0 43.0 0.8 32.4 0.1 0.6 0.0 0.0 0.4 1.1 1.5 1.5 0.9 0.0 0.2 0.5 0.2 0.6 FOXD3 "Genesis, HFH2" ENSG00000187140 "Forkhead box D3" Q9UJU5 1 63322567-63325128 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2" "Cell type enriched" "Detected in some" 5 "Melanocytes: 5.4" "Group enriched" "Detected in some" 6 "melanoma: 9.9;testis cancer: 3.5" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 13.1;SK-MEL-30: 11.2;WM-115: 15.7" "Region enriched" "Detected in single" 13 "olfactory bulb: 3.4" "Group enriched" "Detected in some" 13 "olfactory bulb: 8.6;spinal cord: 2.2" CAB022455 Uncertain NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" "CAB022455: " "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.33e-3)" "unprognostic (4.63e-2)" "unprognostic (7.79e-2)" "unprognostic (8.22e-2)" "unprognostic (3.83e-2)" "unprognostic (1.29e-1)" "unprognostic (9.92e-2)" "unprognostic (3.28e-1)" "unprognostic (3.00e-2)" "unprognostic (8.56e-2)" "unprognostic (5.83e-2)" 0.4 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 1.8 0.0 5.2 0.2 0.2 0.0 0.4 0.4 0.1 1.6 0.0 0.0 0.1 0.1 0.0 0.0 1.9 0.1 0.2 0.1 0.0 0.1 0.0 0.4 1.4 0.2 0.0 0.4 0.5 1.4 0.6 1.3 0.1 0.2 0.0 1.1 1.5 0.0 0.0 0.2 0.2 0.0 1.5 1.5 0.0 0.1 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.3 0.0 0.0 13.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.7 0.0 11.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.0 0.7 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 1.0 0.3 0.2 0.3 0.0 0.0 0.0 0.2 0.0 FOXS1 "FKHL18, FREAC10" ENSG00000179772 "Forkhead box S1" O43638 20 31844303-31845604 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Peritubular cells: 56.8;Sertoli cells: 131.5;Smooth muscle cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;hTERT-RPE1: 13.1;RH-30: 10.9;U-2 OS: 14.1;U-251 MG: 4.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042475 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA042475: AB_10964265" "unprognostic (2.28e-1)" "unprognostic (8.05e-2)" "unprognostic (1.72e-2)" "unprognostic (5.89e-2)" "unprognostic (3.24e-1)" "unprognostic (1.86e-1)" "unprognostic (3.10e-2)" "unprognostic (4.23e-1)" "unprognostic (2.65e-1)" "unprognostic (1.72e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (1.10e-8)" "unprognostic (1.09e-3)" "unprognostic (2.04e-2)" "unprognostic (5.02e-2)" "unprognostic (9.00e-2)" 4.5 1.6 2.4 1.4 2.4 0.0 2.8 2.6 3.8 3.7 1.7 1.4 0.3 3.9 2.4 1.0 1.9 2.0 9.7 2.2 2.3 5.4 0.8 5.3 2.5 2.6 2.5 2.0 0.9 0.6 2.3 4.8 2.7 2.4 0.6 0.0 1.1 3.1 1.7 1.5 1.4 1.2 2.2 3.0 1.2 5.5 2.6 1.0 3.5 1.7 0.9 2.6 2.4 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.9 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.1 0.0 14.1 0.0 4.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.4 2.6 3.8 2.2 2.3 2.6 2.5 2.7 2.2 2.6 2.3 4.3 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 1.2 0.0 1.1 2.6 0.0 0.0 0.0 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.9 4.9 5.0 0.2 1.8 8.4 0.0 0.0 0.0 0.0 0.0 5.7 0.0 56.8 0.0 0.1 0.0 0.0 0.0 0.1 131.5 0.4 31.5 0.6 0.5 0.1 0.3 0.3 0.1 6.6 0.0 0.1 FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 36.4" "Group enriched" "Detected in many" 7 "Early spermatids: 73.7;Inhibitory neurons: 126.1;Late spermatids: 144.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HEL: 163.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA 58000 "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" 5.3 2.5 0.9 0.8 1.1 0.2 4.8 4.2 1.3 5.0 2.0 6.4 2.1 19.7 36.4 1.0 4.1 3.7 6.4 1.1 1.3 17.0 0.9 2.4 0.0 2.0 1.3 1.4 6.6 5.0 1.0 5.5 1.2 1.1 1.7 1.3 0.8 3.4 0.9 3.3 5.4 14.2 3.0 0.4 1.0 4.2 1.2 1.2 0.7 0.8 0.5 2.1 2.3 3.8 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 163.8 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.4 3.7 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 4.2 1.3 1.1 1.3 2.0 1.3 1.2 3.0 1.2 3.8 0.4 0.0 0.6 13.1 0.3 1.3 0.2 0.0 0.6 2.0 0.1 0.1 2.9 2.8 0.0 1.8 0.0 0.5 0.0 0.2 0.0 0.3 73.7 1.5 7.7 0.4 0.0 3.0 16.2 0.0 0.3 11.2 0.5 1.3 5.1 0.2 3.9 0.0 0.5 0.0 126.1 2.4 0.0 0.6 1.2 144.7 0.6 0.1 0.0 6.5 0.6 4.0 0.0 7.1 4.3 0.2 0.0 1.5 0.0 0.1 13.0 1.3 0.0 0.1 0.0 0.6 2.8 0.8 0.9 0.0 1.1 0.3 0.1 6.1 4.7 0.1 FRMD6 "C14orf31, EX1, MGC17921, willin" ENSG00000139926 "FERM domain containing 6" Q96NE9 14 51489100-51730727 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.6;Early spermatids: 219.1;Late spermatids: 473.0;Suprabasal keratinocytes: 137.5;Urothelial cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 351.1;fHDF/TERT166: 765.6;U-138 MG: 290.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001297 Uncertain Supported Approved Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA001297: AB_1078913" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.84e-1)" "unprognostic (2.29e-1)" "unprognostic (2.64e-2)" "unprognostic (8.05e-2)" "unprognostic (8.19e-2)" "unprognostic (3.55e-3)" "unprognostic (1.28e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.66e-4)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.28e-4)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (1.20e-2)" 12.1 13.4 5.2 9.5 5.2 1.2 27.1 12.6 6.7 28.1 8.4 16.0 5.2 53.6 11.3 59.8 13.4 33.0 7.3 6.4 4.5 4.2 10.4 8.6 5.5 5.7 8.1 25.9 5.0 2.4 3.4 14.1 4.9 27.7 10.8 1.5 21.5 30.7 7.4 43.2 7.5 46.8 5.4 12.0 7.2 31.0 5.8 12.6 6.6 6.8 12.7 31.5 30.1 5.6 71.4 14.1 20.1 42.1 40.1 67.6 8.8 351.1 163.2 169.5 146.0 51.9 16.4 1.9 10.6 765.6 47.6 82.8 5.7 113.8 200.3 1.1 8.6 0.3 7.6 2.2 46.8 0.2 4.2 58.8 40.9 152.0 200.5 77.8 52.6 3.7 0.7 24.6 181.8 12.2 7.1 0.2 3.9 0.2 27.4 0.8 79.1 0.7 33.4 113.7 4.1 44.9 27.8 3.9 31.3 37.7 3.0 1.0 242.6 290.7 97.6 73.3 73.5 18.9 17.3 0.2 19.3 0.3 114.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.0 0.1 5.2 5.2 12.6 6.7 6.4 4.5 5.7 8.1 4.9 5.4 5.8 5.6 6.9 3.2 1.5 34.6 0.8 111.4 160.6 42.4 41.5 0.4 40.5 49.4 2.9 8.6 11.6 0.0 0.0 40.1 1.5 0.0 0.0 16.9 219.1 2.0 41.1 14.4 0.0 2.5 45.2 2.9 4.8 57.8 1.1 3.6 1.3 0.9 9.3 4.2 3.8 0.0 22.5 0.3 10.2 0.3 21.1 473.0 17.7 1.5 32.0 68.4 0.7 8.2 0.0 74.9 5.9 64.0 0.0 22.2 3.7 52.0 0.1 0.4 2.7 0.5 6.6 24.5 28.0 10.2 9.8 115.7 137.5 39.0 3.3 0.9 0.1 130.7 FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1381.3;tongue: 838.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 225.1;Hepatocytes: 651.7;Leydig cells: 430.3;Muller glia cells: 343.4;Skeletal myocytes: 188.7;Smooth muscle cells: 205.7" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.0" "Group enriched" "Detected in many" 4 "B-cells: 11.0;T-cells: 6.9" "Cell line enhanced" "Detected in some" "ASC diff: 46.7;ASC TERT1: 13.5;HSkMC: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "HPA026873: AB_1855471" "unprognostic (5.58e-3)" "unprognostic (6.60e-2)" "unprognostic (3.37e-2)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.91e-4)" "unprognostic (1.54e-2)" "unprognostic (1.72e-2)" "unprognostic (3.54e-3)" "unprognostic (8.13e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.59e-8)" "unprognostic (9.97e-3)" "unprognostic (2.25e-1)" "unprognostic (1.65e-1)" "unprognostic (1.92e-2)" 141.4 26.1 496.5 9.6 528.9 2.2 125.1 506.1 637.3 291.9 616.5 168.3 14.3 173.3 62.1 70.7 187.3 56.3 557.7 487.5 503.4 28.6 558.7 85.8 6.6 568.0 515.0 144.7 19.2 3.8 39.8 29.3 494.8 116.0 25.6 35.9 37.2 73.5 1381.3 48.3 67.2 104.5 511.1 20.8 72.6 12.1 560.2 8.2 38.0 838.7 6.7 80.0 194.9 498.6 1.1 0.0 0.0 0.2 46.7 13.5 1.3 5.7 0.1 0.0 0.0 0.0 0.3 3.8 1.5 0.0 0.1 1.0 1.1 0.7 0.0 3.4 1.3 0.7 0.0 1.9 5.2 0.3 0.4 19.3 0.0 0.1 0.5 0.5 0.2 0.1 1.0 3.7 0.1 0.0 0.1 0.8 0.2 2.8 0.6 0.0 0.2 1.1 0.0 0.0 0.3 0.2 0.7 0.2 1.8 0.3 0.2 6.1 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.4 0.9 0.6 7.7 1.6 0.3 0.0 1.3 0.7 0.8 11.0 3.6 1.5 0.3 6.9 0.7 0.9 0.5 2.1 0.8 0.6 6.9 0.6 496.5 528.9 506.1 637.3 487.5 503.4 568.0 515.0 494.8 511.1 560.2 498.6 46.1 0.0 0.0 44.4 15.8 29.4 3.7 2.7 8.0 1.8 4.4 18.0 0.3 11.5 0.8 25.8 4.2 1.2 9.5 42.2 0.0 0.1 1.9 2.2 47.4 13.3 0.0 8.4 3.7 4.9 1.6 225.1 2.0 1.2 0.0 0.1 36.0 651.7 4.4 0.0 0.4 0.8 2.0 14.4 49.0 12.0 430.3 5.3 53.4 2.8 1.0 343.4 1.0 1.5 0.5 1.1 5.3 128.2 2.5 3.3 0.4 0.2 12.6 8.6 118.3 188.7 205.7 10.7 21.7 3.0 27.3 2.9 18.8 0.1 0.7 2.5 FXYD6 ENSG00000137726 "FXYD domain containing ion transport regulator 6" Q9H0Q3 11 117836976-117877486 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 163.9;Leydig cells: 237.9;Muller glia cells: 128.7;Peritubular cells: 363.8;Sertoli cells: 355.0;Theca cells: 141.8" "Cancer enriched" "Detected in all" 6 "glioma: 71.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "classical monocyte: 37.7" "Lineage enriched" "Detected in many" 6 "monocytes: 37.7" "Cell line enhanced" "Detected in some" "AF22: 136.0;HAP1: 92.9;RH-30: 57.1;SCLC-21H: 204.5;SH-SY5Y: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041334, HPA042284" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA041334: AB_10970752, HPA042284: AB_2677931" "unprognostic (2.18e-3)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.31e-2)" "unprognostic (1.15e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.51e-2)" "unprognostic (3.78e-2)" "unprognostic (1.07e-2)" "prognostic favorable (5.97e-4)" "unprognostic (3.44e-2)" "prognostic favorable (4.38e-5)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.60e-4)" 58.4 116.3 230.8 30.1 258.5 9.8 39.5 82.5 293.2 112.3 28.1 371.1 22.2 321.5 61.0 29.8 181.6 93.1 117.1 244.3 187.3 70.6 32.8 86.6 30.0 91.8 173.6 281.1 30.1 9.8 175.0 16.7 149.5 107.8 35.9 47.1 29.5 73.2 37.3 22.2 104.6 197.6 71.4 151.9 98.9 86.6 136.4 31.2 66.5 78.3 18.9 202.9 80.4 179.3 0.3 0.9 136.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.1 4.8 0.7 92.9 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.3 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 2.2 0.2 2.6 0.0 1.7 6.3 0.5 27.2 0.0 0.0 0.1 57.1 1.0 3.5 0.1 204.5 114.0 0.0 0.5 5.1 36.9 2.4 2.4 0.0 0.0 30.0 0.5 0.0 0.4 0.3 0.1 1.0 0.4 0.4 0.0 37.7 0.0 0.0 9.4 0.6 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.9 0.0 0.1 0.6 0.0 9.9 230.8 258.5 82.5 293.2 244.3 187.3 91.8 173.6 149.5 71.4 136.4 179.3 72.2 6.4 2.2 0.0 1.1 6.6 2.4 1.1 0.6 3.5 2.1 21.5 9.3 1.5 0.7 0.0 2.1 0.8 1.0 0.0 1.9 6.4 3.6 0.6 23.9 71.8 12.5 10.7 0.0 0.4 1.1 78.6 0.5 1.0 0.0 29.7 163.9 1.6 72.7 1.7 0.0 0.2 6.1 32.4 9.6 14.3 237.9 18.7 16.0 0.0 9.8 128.7 1.0 0.0 0.0 0.4 0.0 363.8 1.2 4.9 0.0 0.1 1.7 4.4 355.0 49.6 79.6 4.6 3.5 1.4 3.8 1.4 1.4 141.8 0.0 1.7 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.2;Microglial cells: 23.4;Oligodendrocyte precursor cells: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cell line enhanced" "Detected in many" "WM-115: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" 4.3 4.9 9.2 3.9 9.3 0.7 3.7 8.4 12.6 11.0 7.6 6.1 3.8 9.1 3.1 7.8 6.0 5.6 5.0 9.1 9.5 1.4 0.9 5.2 2.9 13.4 9.5 6.3 1.4 3.0 4.2 5.1 10.1 4.8 6.3 0.5 25.6 3.6 1.9 27.7 5.0 9.9 10.7 2.7 2.4 4.8 15.9 22.3 1.9 1.9 3.2 6.7 10.6 13.1 0.1 0.9 5.4 2.3 4.7 9.6 10.9 3.2 3.2 1.8 2.6 0.6 0.2 1.1 0.7 10.4 3.3 12.2 0.3 1.8 0.6 0.1 0.6 0.4 0.2 0.4 3.4 0.3 2.7 11.7 4.6 5.5 0.6 4.0 3.7 4.3 1.6 0.2 3.4 0.4 4.2 0.2 1.9 11.5 1.3 2.7 2.4 0.2 0.0 0.4 0.3 2.2 1.0 0.0 6.7 1.0 0.0 0.3 3.4 0.3 1.6 0.5 0.1 0.2 0.2 2.5 1.9 0.4 43.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 4.5 0.3 0.0 0.1 15.0 4.6 0.3 0.2 0.1 4.7 1.3 2.2 9.2 9.3 8.4 12.6 9.1 9.5 13.4 9.5 10.1 10.7 15.9 13.1 0.7 0.0 0.5 2.9 0.1 4.2 2.0 3.3 7.4 0.0 2.2 2.4 1.0 1.5 0.9 0.0 0.0 0.3 0.3 1.5 0.0 0.6 0.2 0.2 2.1 1.2 0.0 2.7 0.5 0.0 0.4 7.5 0.0 0.3 0.0 1.2 1.4 0.0 37.2 0.0 0.3 1.3 4.1 1.3 0.8 0.0 4.7 9.6 5.4 23.4 0.7 0.4 0.0 24.6 0.5 0.3 2.5 5.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 3.7 3.3 0.6 0.3 4.2 8.1 0.8 0.7 0.1 4.1 1.4 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 77.1;Excitatory neurons: 178.4;Inhibitory neurons: 184.7;Microglial cells: 48.7;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 165.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 5.3;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA028757: AB_2294383, HPA074886: AB_2732270" "unprognostic (3.15e-2)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (3.40e-2)" "unprognostic (3.12e-2)" "unprognostic (1.19e-3)" "unprognostic (5.58e-3)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (6.88e-4)" "unprognostic (2.22e-1)" "unprognostic (3.23e-7)" "unprognostic (6.39e-2)" "unprognostic (6.60e-2)" "unprognostic (7.04e-3)" "unprognostic (1.78e-5)" 3.1 6.0 5.7 0.3 5.7 0.0 4.4 11.6 6.0 6.0 2.0 2.9 1.8 7.4 5.2 4.4 5.4 3.7 11.3 6.9 5.2 2.1 1.8 2.4 1.3 4.7 4.5 4.5 2.1 6.6 2.0 1.4 5.8 6.2 1.9 1.3 5.0 4.0 1.5 2.8 1.8 6.7 4.6 1.8 1.8 2.9 4.2 0.6 5.7 1.8 1.3 4.6 3.3 11.2 0.5 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 1.0 1.2 0.3 0.0 1.0 0.1 0.4 0.6 1.8 0.0 0.1 0.0 0.8 0.0 1.9 1.2 0.4 0.4 0.1 0.1 1.5 0.0 0.0 1.5 0.7 1.9 0.8 0.7 0.1 0.5 0.0 0.3 0.4 5.3 1.6 0.1 1.1 3.4 1.9 2.5 1.2 3.9 0.8 2.7 0.4 0.6 0.9 0.0 0.0 0.2 1.0 0.0 0.4 2.3 2.4 1.0 0.4 0.5 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 5.7 5.7 11.6 6.0 6.9 5.2 4.7 4.5 5.8 4.6 4.2 11.2 1.3 0.0 0.0 77.1 0.5 2.7 1.7 0.4 2.8 8.0 3.1 4.3 6.8 4.3 2.0 3.7 0.0 0.6 0.2 0.9 1.9 0.3 2.2 1.0 21.1 1.5 1.2 0.4 178.4 0.6 0.1 4.8 5.6 1.2 0.0 2.4 1.8 2.5 0.8 1.7 184.7 0.8 0.0 1.3 1.9 1.0 7.5 1.3 1.8 48.7 0.0 4.0 0.0 45.2 165.3 0.4 1.6 3.4 0.5 3.3 0.6 1.8 0.1 1.0 0.0 7.1 4.0 3.5 3.9 2.7 2.0 0.3 0.7 1.0 0.8 1.2 GCK "HK4, MODY2" ENSG00000106633 Glucokinase P35557 7 44143213-44198170 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 12.6;choroid plexus: 7.4;heart muscle: 8.8;liver: 21.5;pituitary gland: 23.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Cardiomyocytes: 4.9;Fibroblasts: 5.2;Horizontal cells: 5.0;Smooth muscle cells: 3.7" "Cancer enhanced" "Detected in some" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.3;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007034, HPA007093" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "HPA007034: AB_1079050, HPA007093: AB_1079051" "unprognostic (3.09e-1)" "unprognostic (2.99e-2)" "unprognostic (3.32e-2)" "unprognostic (6.64e-7)" "unprognostic (8.00e-2)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-1)" "unprognostic (5.48e-2)" "unprognostic (8.11e-3)" "unprognostic (3.08e-1)" "unprognostic (3.79e-3)" "unprognostic (2.01e-2)" "unprognostic (3.24e-1)" "unprognostic (4.36e-2)" "unprognostic (1.53e-1)" 0.8 0.3 8.9 0.3 8.3 0.2 0.7 8.1 9.5 2.8 7.4 0.5 0.1 1.2 0.8 0.4 1.2 0.5 8.8 8.2 11.0 1.2 21.5 0.4 0.2 9.0 9.9 1.4 1.8 0.1 23.9 1.6 9.1 1.2 0.2 1.0 0.3 0.7 0.2 0.7 0.5 0.3 8.3 0.6 0.6 0.4 12.6 0.1 0.5 0.1 0.2 1.1 2.0 7.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 1.2 1.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.3 2.3 0.7 0.1 0.1 0.3 2.0 0.4 0.8 0.1 0.0 0.1 0.0 0.3 8.9 8.3 8.1 9.5 8.2 11.0 9.0 9.9 9.1 8.3 12.6 7.9 0.3 0.0 0.0 0.7 0.3 1.1 0.7 0.0 1.2 5.0 0.1 0.8 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 1.3 0.5 2.4 0.0 1.8 0.0 0.2 5.2 0.0 0.0 0.0 2.4 0.0 0.4 0.7 5.0 2.4 0.0 0.0 0.0 0.7 0.3 0.9 0.1 0.0 1.0 0.0 2.8 0.0 0.5 1.0 0.1 0.1 2.2 0.2 1.7 0.0 0.1 0.0 0.8 0.0 0.6 3.7 0.5 1.1 0.0 0.1 0.8 0.3 0.5 0.0 0.7 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GFRA1 "GDNFR, GDNFRA, GFR-ALPHA-1, RET1L, RETL1, TRNR1" ENSG00000151892 "GDNF family receptor alpha 1" P56159 10 116056925-116273284 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 40.5;Breast glandular cells: 33.1;Fibroblasts: 51.2;Hepatocytes: 42.2;Oligodendrocyte precursor cells: 91.0;Skeletal myocytes: 100.1" "Cancer enriched" "Detected in many" 11 "breast cancer: 40.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 44.7;BJ hTERT+ SV40 Large T+ RasG12V: 77.2;EFO-21: 46.5;fHDF/TERT166: 89.3;HBF TERT88: 63.2;MCF7: 59.5;U-251 MG: 53.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043829 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 140000 "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA043829: AB_2678689" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (7.60e-2)" "unprognostic (1.06e-3)" "unprognostic (4.10e-2)" "unprognostic (6.95e-3)" "unprognostic (2.35e-3)" "unprognostic (1.48e-3)" "unprognostic (3.16e-1)" "unprognostic (2.06e-3)" "unprognostic (1.31e-2)" "unprognostic (2.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.20e-3)" "unprognostic (1.69e-1)" "unprognostic (2.27e-2)" "unprognostic (3.64e-2)" 10.9 3.4 7.2 4.2 14.9 0.0 23.2 2.6 9.5 9.9 0.3 18.3 1.7 4.9 20.5 6.9 17.2 5.6 4.8 9.7 18.0 6.0 16.0 2.8 4.0 7.8 28.5 4.5 6.6 2.7 3.2 0.0 7.2 4.5 3.9 3.2 6.0 5.4 4.3 7.2 8.2 4.8 6.2 3.9 8.2 3.1 7.6 4.1 2.8 13.9 6.4 7.0 9.2 6.1 0.1 3.7 12.2 0.0 0.0 0.1 0.0 7.9 0.4 44.7 77.2 0.0 0.0 0.0 46.5 89.3 0.0 0.0 0.1 0.0 63.2 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 2.5 0.0 11.5 0.0 3.9 0.0 9.1 0.0 0.0 5.6 59.5 7.6 0.0 5.0 0.0 0.0 0.0 1.9 0.0 5.0 0.0 1.6 0.1 0.0 0.0 0.1 2.1 0.4 0.0 0.4 0.0 0.4 0.1 53.5 0.0 0.0 0.1 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 14.9 2.6 9.5 9.7 18.0 7.8 28.5 7.2 6.2 7.6 6.1 6.1 0.0 0.0 40.5 0.5 5.7 0.0 0.0 1.8 4.1 33.1 11.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 13.2 0.0 0.2 3.2 6.0 0.0 5.1 13.5 0.0 51.2 3.1 0.0 6.3 0.1 0.4 42.2 0.0 0.0 6.6 0.0 0.0 1.0 9.6 12.8 8.1 1.0 5.4 1.9 0.0 12.6 0.0 91.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.5 0.0 100.1 16.7 0.1 10.4 0.7 4.5 0.0 0.7 0.1 0.0 0.2 GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Enteroendocrine cells: 53.1;granulocytes: 26.7;Late spermatids: 20.9;Spermatogonia: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.9" "Region enriched" "Detected in single" 8 "cerebellum: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 32.0" "Not detected" "Not detected" HPA020731 Approved Uncertain "Plasma membrane,Cytosol" NA NA 150000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane" Cytosol "HPA020731: AB_1849635" "unprognostic (1.22e-1)" "unprognostic (6.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.47e-3)" "unprognostic (2.77e-3)" "unprognostic (1.27e-1)" "unprognostic (7.65e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-2)" "unprognostic (1.90e-5)" "unprognostic (2.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" 1.8 1.6 0.0 2.1 0.2 0.0 1.6 2.5 0.3 7.4 0.0 13.0 2.7 0.5 2.5 2.3 1.2 1.9 5.7 0.1 0.2 0.5 0.5 2.0 0.1 0.1 0.1 1.3 3.7 0.0 2.0 0.0 0.2 4.1 3.8 0.0 3.2 5.9 0.2 3.1 3.3 2.0 0.1 0.0 6.3 4.2 0.1 0.5 0.8 0.4 0.1 5.1 7.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.1 0.0 0.0 2.0 1.2 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 32.0 0.5 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 8.7 0.0 0.0 0.0 53.1 0.0 0.2 0.2 0.2 0.5 0.0 0.0 26.7 0.3 0.0 0.0 0.1 0.0 0.1 0.2 6.1 0.0 0.2 20.9 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.8 8.4 0.1 0.0 0.3 0.0 0.1 0.0 0.1 GGTA1 "GGTA, GGTA1P, GLYT2" ENSG00000204136 "Glycoprotein alpha-galactosyltransferase 1 (inactive)" Q4G0N0 9 121444991-121499844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 133.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Endothelial cells: 2.2;granulocytes: 3.8;Macrophages: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 22.7;intermediate monocyte: 17.9;myeloid DC: 12.7;plasmacytoid DC: 27.5" "Group enriched" "Detected in many" 19 "dendritic cells: 27.5;monocytes: 22.7" "Group enriched" "Detected in some" 6 "AN3-CA: 4.3;HEL: 1.3;SH-SY5Y: 4.9" HPA023262 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "HPA023262: AB_1849651" "unprognostic (1.71e-1)" "unprognostic (9.98e-2)" "unprognostic (4.49e-2)" "prognostic favorable (5.33e-5)" "unprognostic (1.67e-2)" "unprognostic (2.85e-2)" "unprognostic (8.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.53e-3)" "unprognostic (9.24e-2)" "unprognostic (2.64e-2)" "unprognostic (1.44e-2)" "unprognostic (6.87e-2)" 33.4 18.5 15.4 10.1 18.9 68.2 40.4 12.7 19.9 17.2 14.4 14.9 12.0 10.7 7.4 24.2 10.1 23.1 18.7 16.4 15.3 5.7 15.0 21.9 25.7 13.9 15.2 7.6 5.0 4.8 41.7 13.7 6.5 15.4 0.5 133.2 15.3 5.0 13.6 16.1 12.5 14.1 40.4 8.7 4.1 16.0 9.9 5.1 13.4 10.4 21.4 14.9 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.7 0.0 0.0 17.9 0.0 0.7 0.0 0.0 12.7 0.0 0.0 0.0 1.2 0.1 0.4 27.5 0.0 7.2 15.4 18.9 12.7 19.9 16.4 15.3 13.9 15.2 13.7 14.1 16.0 14.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.0;Microglial cells: 76.8;Oligodendrocytes: 154.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 35.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 119.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" 9.1 12.2 6.7 5.6 7.8 0.9 8.9 35.8 6.2 8.2 8.4 12.8 14.2 6.4 6.9 10.0 5.5 7.5 6.3 6.0 6.7 13.3 16.8 8.4 3.5 5.7 8.5 12.7 4.7 8.7 6.4 13.4 7.2 5.8 14.2 13.2 10.9 5.8 4.1 10.4 11.5 7.0 7.5 4.4 9.1 3.9 8.8 4.9 4.1 4.9 5.1 6.6 4.6 8.0 9.6 8.5 5.6 9.7 18.6 17.6 2.0 17.6 23.2 13.3 25.2 7.1 23.6 5.8 8.5 14.4 16.8 14.0 12.1 11.4 27.1 2.2 13.4 9.7 15.0 7.2 17.9 4.2 19.0 12.1 7.8 16.6 18.6 9.7 119.4 4.3 3.9 6.0 25.4 5.9 2.6 7.4 2.7 9.7 5.9 5.8 22.6 7.3 12.3 10.1 17.9 3.7 18.0 11.0 38.1 3.8 7.9 5.8 41.8 12.7 15.7 14.3 15.8 2.5 3.7 1.3 12.9 7.0 18.8 0.0 2.1 0.0 0.3 1.6 0.5 0.2 0.8 0.4 1.8 0.2 0.5 0.7 0.0 0.2 2.3 1.9 2.0 0.9 6.7 7.8 35.8 6.2 6.0 6.7 5.7 8.5 7.2 7.5 8.8 8.0 16.9 0.0 15.4 4.9 6.2 4.8 10.1 8.3 26.2 10.3 18.8 19.4 8.1 7.2 8.8 11.0 10.4 22.7 12.1 21.3 5.9 13.0 3.9 4.0 5.4 22.6 20.4 9.4 79.0 13.8 12.7 14.0 28.1 4.9 2.5 11.8 16.4 27.2 16.4 8.4 41.5 27.1 10.2 13.3 4.4 5.1 6.2 10.7 8.8 76.8 13.7 13.1 4.1 35.7 154.9 16.9 28.2 17.7 7.1 5.3 32.4 18.3 18.2 16.6 13.1 6.6 9.4 29.8 25.9 27.9 6.5 33.0 5.9 17.1 26.4 13.3 GLI1 GLI ENSG00000111087 "GLI family zinc finger 1" P08151 12 57459785-57472268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 11.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 6.5;Leydig cells: 29.5;Peritubular cells: 42.9;Sertoli cells: 13.1;Theca cells: 7.8" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 24.2;BJ hTERT+: 16.9;NTERA-2: 14.0;RH-30: 60.6;U-266/70: 16.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009460, HPA065172, HPA068903" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "CAB009460: AB_2111764, HPA065172: AB_2685427, HPA068903: AB_2732122" "unprognostic (4.97e-4)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (5.58e-3)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (9.00e-2)" "unprognostic (1.88e-1)" "unprognostic (1.43e-1)" "unprognostic (8.52e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-8)" "unprognostic (4.59e-3)" "unprognostic (2.98e-2)" "unprognostic (2.78e-2)" "unprognostic (1.04e-2)" 2.4 1.2 1.3 1.7 1.6 0.5 1.5 3.5 1.9 11.1 0.4 3.0 2.5 9.5 6.6 0.6 3.7 5.5 2.1 1.0 2.1 1.4 0.8 1.6 0.7 1.9 2.4 1.5 0.8 0.0 1.0 0.5 1.7 4.2 4.1 0.0 1.5 2.8 0.6 1.7 3.3 2.4 1.7 0.9 1.9 4.7 4.2 0.3 2.3 1.8 1.0 4.4 3.1 1.1 0.1 9.8 3.2 24.2 0.7 0.1 0.3 0.9 16.9 2.1 2.3 0.3 0.7 3.1 0.0 0.5 2.3 1.7 1.8 1.1 0.4 2.7 0.3 0.1 1.2 0.2 2.7 0.7 1.4 0.8 0.4 3.1 1.0 4.2 0.3 2.2 0.4 7.8 1.0 0.0 0.7 0.5 14.0 0.8 0.9 1.2 60.6 1.7 2.7 0.0 0.1 0.1 0.2 0.1 0.4 2.4 0.0 0.3 0.1 2.2 7.7 0.6 0.3 16.7 1.0 5.7 2.0 1.3 3.8 0.8 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 1.9 0.0 0.0 0.1 0.2 0.0 1.3 1.6 3.5 1.9 1.0 2.1 1.9 2.4 1.7 1.7 4.2 1.1 0.4 0.0 0.0 2.0 0.7 0.1 0.4 0.3 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.1 3.5 0.5 0.0 0.0 0.1 0.0 0.1 6.5 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.4 2.5 29.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.1 0.2 0.0 1.3 0.0 0.0 13.1 1.9 1.6 0.3 1.1 0.2 0.6 0.1 0.5 7.8 0.1 0.1 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GLYATL2 "BXMAS2-10, MGC24009" ENSG00000156689 "Glycine-N-acyltransferase like 2" Q8WU03 11 58834065-58904215 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 12.0;cervix: 19.9;salivary gland: 33.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.8;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 3.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 4 "breast cancer: 16.7;endometrial cancer: 15.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 5.3;BJ hTERT+ SV40 Large T+ RasG12V: 3.7;HAP1: 6.0;SK-BR-3: 14.1;U-2197: 6.6" "Low region specificity" "Detected in many" "HPA060292, HPA065454" Uncertain Approved Mitochondria NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" Mitochondria "HPA060292: AB_2684245, HPA065454: " "unprognostic (1.02e-2)" "unprognostic (3.79e-3)" "unprognostic (8.11e-4)" "prognostic favorable (9.05e-7)" "unprognostic (1.05e-1)" "unprognostic (8.41e-2)" "unprognostic (2.66e-2)" "unprognostic (9.98e-3)" "unprognostic (1.27e-1)" "unprognostic (9.18e-3)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (7.42e-5)" "unprognostic (7.79e-3)" "unprognostic (8.28e-2)" "unprognostic (9.11e-3)" "unprognostic (2.31e-2)" 0.2 0.1 0.2 0.1 0.3 0.1 12.0 0.2 0.5 19.9 0.0 0.1 0.3 0.4 0.3 0.9 0.1 7.5 0.3 0.2 0.4 0.9 0.1 0.0 0.3 0.7 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.9 0.2 0.3 33.4 0.1 0.0 1.4 0.1 0.3 0.7 0.3 0.1 0.0 0.2 0.1 0.1 0.5 0.4 0.1 0.3 1.1 0.0 0.0 0.4 0.0 0.7 2.6 0.0 1.7 5.3 2.3 3.7 0.0 0.0 0.1 0.0 1.4 1.0 0.4 6.0 0.0 1.9 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.5 0.2 2.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.1 14.1 0.0 0.0 0.0 0.0 0.0 1.8 0.1 6.6 2.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.5 0.2 0.4 0.7 0.2 0.6 0.7 0.2 1.1 0.2 0.0 0.0 0.0 0.0 1.0 2.3 1.4 0.0 0.5 14.8 2.2 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 1.1 0.0 0.0 1.5 1.4 0.0 0.5 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 3.0 0.4 0.1 0.0 0.0 0.0 3.6 0.0 0.2 0.1 0.1 6.6 0.2 0.6 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.9 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPM6B "M6B, MGC17150, MGC54284" ENSG00000046653 "Glycoprotein M6B" Q13491 X 13770939-13938638 "Predicted membrane proteins" "Differentiation, Neurogenesis, Osteogenesis, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 743.2;choroid plexus: 180.7;retina: 207.7" "Cell type enhanced" "Detected in many" "Astrocytes: 633.3;Excitatory neurons: 361.3;Melanocytes: 357.5;Muller glia cells: 1722.4;Oligodendrocyte precursor cells: 408.1;Oligodendrocytes: 1476.6" "Cancer enriched" "Detected in many" 5 "glioma: 192.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 220 "plasmacytoid DC: 77.7" "Lineage enriched" "Detected in single" 268 "dendritic cells: 77.7" "Cell line enhanced" "Detected in many" "AF22: 154.8;AN3-CA: 150.1;ASC TERT1: 74.2;HSkMC: 110.0;SK-MEL-30: 154.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002913 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA002913: AB_2263553" "unprognostic (1.56e-2)" "unprognostic (3.42e-1)" "unprognostic (1.83e-1)" "unprognostic (3.70e-2)" "unprognostic (8.55e-2)" "unprognostic (2.75e-3)" "unprognostic (2.12e-2)" "unprognostic (1.92e-2)" "unprognostic (4.27e-2)" "prognostic favorable (2.67e-4)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (2.38e-3)" "unprognostic (8.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" 7.5 9.3 418.4 6.0 518.8 1.1 26.4 540.4 521.1 27.1 180.7 33.8 5.0 6.3 12.1 11.5 6.5 5.9 15.8 447.8 463.6 7.7 1.1 16.8 2.8 596.3 459.3 4.4 3.2 0.6 17.2 1.3 580.5 21.8 7.8 207.7 14.8 35.2 2.5 13.9 9.2 5.4 533.4 14.5 11.7 3.5 419.9 0.8 5.0 7.5 1.9 9.1 19.7 743.2 0.4 0.4 154.8 150.1 41.6 74.2 0.4 0.9 6.9 0.1 0.0 0.4 0.5 0.7 0.3 0.0 0.6 1.3 7.6 0.8 0.0 0.6 25.2 0.4 10.0 0.4 1.5 0.5 0.9 110.0 0.9 0.0 1.9 0.6 0.0 3.0 0.4 6.8 1.5 0.6 3.4 0.7 48.5 0.1 2.5 2.0 13.7 23.9 0.0 0.5 7.8 4.4 0.8 4.4 154.4 41.9 0.7 3.6 0.3 1.0 1.3 0.3 2.0 0.5 0.3 0.3 1.4 0.3 12.4 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.2 0.1 77.7 0.1 0.7 418.4 518.8 540.4 521.1 447.8 463.6 596.3 459.3 580.5 533.4 419.9 743.2 13.8 0.0 5.1 633.3 15.8 33.0 22.7 5.9 6.8 74.4 37.1 47.1 1.3 1.5 7.8 22.0 87.6 5.0 50.7 3.0 0.0 5.4 1.5 45.8 32.7 12.5 1.2 5.3 361.3 3.7 3.7 54.2 0.0 30.4 4.5 19.7 10.8 0.4 1.2 26.9 144.0 5.0 8.2 1.9 33.5 3.2 24.2 3.7 357.5 40.3 4.6 1722.4 50.4 408.1 1476.6 2.3 6.0 32.0 7.3 26.5 6.1 1.1 11.0 151.4 46.0 137.7 43.6 9.6 13.3 7.0 17.0 13.7 20.5 8.6 3.2 14.8 GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 581.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 327.1;Fibroblasts: 285.8;Hofbauer cells: 814.1;Macrophages: 328.9;Melanocytes: 597.7;Suprabasal keratinocytes: 359.7" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cell line enriched" "Detected in many" 6 "ASC diff: 5015.0" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 33000000 "Cluster 7: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" 152.9 25.9 20.9 41.7 20.9 6.6 135.6 19.0 70.9 303.9 77.6 78.8 22.5 180.9 43.8 111.8 72.8 270.7 323.5 21.2 23.1 32.7 52.5 215.8 169.0 32.2 21.5 77.7 20.6 15.3 12.8 148.6 31.0 30.4 92.9 2.9 66.1 55.8 15.4 581.2 48.5 151.5 27.3 31.9 37.1 26.2 34.6 89.5 51.5 72.4 103.4 190.9 151.0 66.5 19.2 0.8 0.1 0.6 5015.0 908.0 0.4 33.6 564.1 27.9 116.2 0.2 0.8 0.7 1.4 109.5 49.1 118.3 0.7 0.7 14.2 1.3 1.3 0.1 0.9 2.5 61.5 1.5 0.6 630.3 134.8 46.3 4.7 734.9 0.3 1.4 0.3 0.6 150.2 3.5 0.7 0.7 0.6 0.5 0.5 0.4 1.4 7.6 71.2 443.4 2.4 0.6 0.1 175.6 841.5 1.3 2.3 2.8 0.1 163.0 17.8 297.8 5.5 5.1 8.6 1.2 56.3 2.6 166.1 0.6 2.1 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.1 0.1 0.4 0.0 0.5 20.9 20.9 19.0 70.9 21.2 23.1 32.2 21.5 31.0 27.3 34.6 66.5 18.0 19.2 24.3 0.3 3.2 327.1 7.1 58.5 150.2 0.4 6.6 24.5 204.2 2.8 16.0 75.4 0.0 7.2 2.2 0.1 3.9 0.6 3.0 2.5 44.0 15.0 0.0 0.0 0.5 0.8 4.6 285.8 12.2 2.5 22.7 0.1 4.6 5.1 814.1 1.7 1.2 0.0 12.2 188.4 100.7 5.5 129.8 328.9 597.7 12.2 3.2 0.2 1.0 55.8 0.1 0.6 0.0 108.0 10.2 1.9 0.0 1.2 3.4 0.6 0.0 20.6 53.4 3.9 1.4 65.3 359.7 28.9 5.7 0.1 0.0 11.9 GRIA1 "GluA1, GLUR1, GLURA" ENSG00000155511 "Glutamate ionotropic receptor AMPA type subunit 1" P42261 5 153489615-153813869 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 83.7;retina: 32.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 322.4;Inhibitory neurons: 608.8" "Cancer enriched" "Detected in some" 15 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 11.6;ASC diff: 3.5;BJ: 5.5;BJ hTERT+: 2.9;LHCN-M2: 8.1;U-266/70: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035202 Enhanced NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA035202: AB_2674516" "unprognostic (2.51e-1)" "unprognostic (4.76e-3)" "unprognostic (1.97e-1)" "unprognostic (4.20e-2)" "unprognostic (6.95e-2)" "unprognostic (2.43e-1)" "unprognostic (2.61e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (2.35e-2)" "unprognostic (5.14e-4)" "unprognostic (7.97e-2)" "unprognostic (2.96e-2)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (2.80e-1)" "unprognostic (7.61e-2)" 1.2 0.4 38.7 0.1 42.8 0.0 0.4 43.5 79.8 0.2 0.0 0.6 0.2 0.1 0.7 0.1 0.1 0.0 0.8 83.7 23.2 0.1 0.0 9.3 0.0 3.4 3.6 0.2 0.3 0.2 1.2 0.0 2.7 0.1 0.1 32.6 0.1 0.5 0.2 0.3 0.3 1.0 5.3 0.0 0.6 0.9 27.9 0.1 0.3 0.4 0.0 0.1 0.3 18.1 0.0 0.0 11.6 0.0 3.5 2.3 0.0 5.5 2.9 0.3 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 42.8 43.5 79.8 83.7 23.2 3.4 3.6 2.7 5.3 27.9 18.1 0.2 0.0 0.0 43.1 0.0 0.0 0.0 0.0 0.0 36.3 0.3 0.0 1.2 0.0 0.0 0.0 6.2 0.0 0.0 0.2 0.0 0.0 5.1 0.1 5.6 0.4 0.0 0.0 322.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.7 608.8 0.0 0.0 0.0 0.0 3.4 0.0 0.9 0.0 7.5 0.0 49.0 0.0 94.5 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.1 0.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GRIN2A "GluN2A, NMDAR2A" ENSG00000183454 "Glutamate ionotropic receptor NMDA type subunit 2A" Q12879 16 9753404-10182928 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 31.7" "Group enriched" "Detected in some" 13 "Excitatory neurons: 839.8;Inhibitory neurons: 904.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 31.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 4.4;hTERT-RPE1: 1.4;RPMI-8226: 1.8;U-138 MG: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022725 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB022725: " "unprognostic (6.43e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-2)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (2.10e-1)" "unprognostic (2.08e-1)" "unprognostic (5.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (4.79e-3)" "unprognostic (2.05e-1)" "unprognostic (3.92e-3)" "unprognostic (3.33e-2)" 0.3 0.3 4.7 0.0 8.4 0.0 0.1 0.0 31.7 0.3 0.0 0.2 0.3 0.3 2.5 1.1 2.1 0.1 3.0 20.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.2 2.2 0.2 0.3 0.0 0.5 0.2 0.4 0.0 0.0 0.4 2.1 0.1 0.6 0.2 0.2 0.2 0.1 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.3 1.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.4 0.0 31.7 20.0 0.0 0.0 0.0 0.0 0.0 0.1 10.3 0.2 0.0 0.0 16.0 0.0 1.9 2.2 0.5 3.4 10.3 0.3 0.0 18.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2.1 17.2 0.3 0.1 0.5 0.0 0.0 839.8 0.2 0.0 2.7 0.0 0.7 0.0 3.3 0.0 0.3 0.1 1.7 904.7 0.0 0.0 0.3 0.4 15.1 0.9 0.1 0.0 15.9 0.0 15.6 0.0 27.6 65.8 0.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 13.9 0.0 0.0 5.4 8.2 10.0 0.2 0.4 0.0 0.0 0.0 0.1 0.3 GRIP2 KIAA1719 ENSG00000144596 "Glutamate receptor interacting protein 2" Q9C0E4 3 14489107-14556075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13.3;skeletal muscle: 35.8;tongue: 12.5" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 89.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;BJ hTERT+ SV40 Large T+ RasG12V: 1.9;NTERA-2: 2.1;PC-3: 6.1;SCLC-21H: 3.4;U-2 OS: 2.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035673 Approved Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035673: AB_10669776" "unprognostic (1.48e-1)" "unprognostic (6.26e-3)" "unprognostic (2.43e-2)" "unprognostic (3.13e-2)" "unprognostic (5.51e-2)" "unprognostic (1.14e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-2)" "unprognostic (9.14e-2)" "unprognostic (2.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (5.82e-1)" "unprognostic (4.01e-1)" 1.1 1.1 3.0 0.7 2.7 0.0 1.0 0.0 6.2 1.1 0.0 0.8 0.4 1.1 0.4 2.2 0.8 1.2 13.3 0.2 3.5 2.3 0.3 0.4 0.4 2.9 5.8 3.4 0.5 0.3 1.0 3.9 2.1 0.9 1.0 0.3 0.9 0.4 35.8 2.0 1.0 1.0 1.7 1.6 4.5 0.7 9.6 0.3 0.8 12.5 0.7 1.0 1.2 1.8 0.1 0.9 0.0 0.0 0.3 0.2 0.0 0.3 3.1 0.3 1.9 1.2 0.0 0.0 0.7 0.2 0.5 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 1.5 6.1 0.0 0.0 0.0 0.0 0.0 3.4 0.6 0.3 0.0 1.0 1.1 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.0 6.2 0.2 3.5 2.9 5.8 2.1 1.7 9.6 1.8 2.3 0.0 0.5 2.3 0.1 0.0 0.1 0.0 1.2 14.9 0.1 1.3 8.5 0.0 0.6 0.0 14.6 0.0 0.7 0.1 0.0 0.0 3.0 2.1 1.4 0.8 4.2 0.0 3.0 0.2 0.0 2.0 2.0 4.9 0.0 0.0 1.1 0.0 0.1 0.0 89.0 0.1 0.0 0.0 0.0 5.2 4.1 0.7 0.0 2.8 0.0 0.5 0.0 0.5 0.9 0.0 0.0 2.2 0.3 0.1 0.0 0.2 0.0 21.9 19.7 4.3 14.7 0.1 0.8 0.2 0.0 0.1 0.3 1.1 0.0 0.0 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.0;Plasma cells: 28.4;Squamous epithelial cells: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 116.0;HSkMC: 115.6" "Low region specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Supported Vesicles,Cytosol NA NA 1200000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Vesicles "CAB040547: , HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 73.7 84.4 92.3 11.9 109.9 10.7 81.2 86.7 104.6 165.9 111.5 115.2 26.3 70.6 43.7 61.6 102.7 22.0 99.7 93.5 104.7 86.8 35.6 45.2 14.3 94.3 97.1 240.9 54.5 53.6 113.7 9.3 91.9 159.0 17.7 25.1 55.2 80.7 218.4 88.2 65.5 34.2 93.9 52.6 88.3 41.9 105.2 15.9 97.9 108.4 12.6 108.3 144.5 90.6 0.0 3.5 37.8 38.9 44.0 116.0 7.2 24.5 42.6 22.1 28.0 6.7 0.0 0.7 25.5 61.1 18.0 0.2 3.1 0.2 28.6 1.5 0.8 14.0 0.4 9.3 29.6 1.1 25.2 115.6 1.0 32.7 0.0 58.5 16.1 11.6 4.2 0.7 48.5 0.3 19.5 24.6 6.7 0.7 32.4 23.8 0.1 0.2 6.6 0.5 8.1 18.7 0.0 1.0 13.0 21.7 38.6 7.0 0.2 24.3 1.2 35.3 1.9 11.9 19.0 1.3 36.7 0.5 0.3 1.8 3.8 29.6 3.1 6.3 3.1 8.8 8.8 3.4 23.0 6.2 34.4 15.1 2.2 18.0 4.1 29.8 9.4 10.8 92.3 109.9 86.7 104.6 93.5 104.7 94.3 97.1 91.9 93.9 105.2 90.6 2.0 0.0 4.8 16.0 4.5 4.8 2.4 0.9 20.5 1.5 4.5 4.3 61.0 2.8 11.5 3.7 0.0 0.5 6.1 0.4 0.0 0.2 1.9 2.8 10.3 5.8 0.0 10.9 1.5 0.0 0.2 19.2 14.8 2.7 2.5 4.4 1.8 0.8 1.5 3.3 2.6 1.3 2.0 0.8 2.3 10.4 15.5 3.4 5.4 11.2 0.7 7.2 8.2 12.5 0.7 0.1 0.0 10.5 28.4 0.8 0.4 1.2 9.9 0.3 6.6 5.6 13.6 0.3 0.8 27.0 2.8 0.5 5.1 4.0 0.7 1.6 GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 929.9" "Group enriched" "Detected in many" 4 "Fibroblasts: 59.0;Leydig cells: 143.5;Muller glia cells: 213.3;Peritubular cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 21.6;HHSteC: 10.3;HSkMC: 10.9" "HPA055972, HPA055973" Approved Uncertain "Cytokinetic bridge,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 5: Breast - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Cytokinetic bridge" "HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (1.46e-2)" "unprognostic (8.64e-3)" "unprognostic (5.58e-2)" "unprognostic (1.42e-1)" "unprognostic (5.34e-3)" "unprognostic (8.09e-2)" "unprognostic (9.64e-4)" "unprognostic (1.31e-2)" "unprognostic (1.44e-1)" "unprognostic (9.16e-2)" "unprognostic (3.31e-1)" "unprognostic (1.92e-2)" "unprognostic (1.42e-2)" "unprognostic (3.74e-2)" "unprognostic (4.39e-2)" "unprognostic (3.03e-3)" "unprognostic (1.40e-1)" 21.7 6.4 60.3 4.6 65.3 0.5 929.9 60.4 71.1 72.5 62.9 13.9 2.3 35.1 32.9 11.6 62.0 25.8 17.0 61.4 54.5 5.5 3.9 18.0 5.0 57.2 55.4 213.9 4.7 0.2 9.4 0.8 56.7 27.9 7.8 12.4 7.9 32.6 3.9 12.2 10.3 26.5 60.1 7.7 13.2 11.4 53.5 6.4 9.1 14.0 6.5 27.9 47.6 58.6 0.0 0.0 0.0 0.0 1.7 1.6 0.4 1.3 0.0 0.3 0.2 0.0 0.0 0.1 0.0 21.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.8 0.0 0.0 10.3 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.6 0.0 3.9 0.9 0.7 60.3 65.3 60.4 71.1 61.4 54.5 57.2 55.4 56.7 60.1 53.5 58.6 2.5 0.0 0.5 32.3 0.0 6.6 0.9 0.2 0.0 2.0 0.5 0.8 0.9 1.5 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.0 9.0 0.3 12.3 2.2 0.0 2.1 0.1 0.0 0.1 59.0 1.1 0.3 0.0 0.6 5.7 0.0 0.3 0.0 0.5 0.1 0.0 0.6 9.3 15.1 143.5 0.6 10.6 1.9 0.0 213.3 0.0 2.0 0.3 0.0 0.0 127.2 0.1 0.1 0.1 0.0 0.0 6.8 26.3 2.3 9.4 2.0 1.8 1.0 6.5 0.0 2.8 2.4 0.1 0.6 GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 38.4;Alveolar cells type 2: 56.1;Breast glandular cells: 37.4;Breast myoepithelial cells: 24.9;Distal tubular cells: 19.6;Ductal cells: 21.8;Smooth muscle cells: 49.4" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.2;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.2" "Cell line enhanced" "Detected in some" "HAP1: 6.8;HEK 293: 5.5;Karpas-707: 9.7;MOLT-4: 18.5;RPTEC TERT1: 12.1;RT4: 14.2;SH-SY5Y: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" 14.4 7.8 10.1 17.0 24.1 1.2 15.4 2.8 14.0 14.5 0.1 27.1 8.7 16.1 6.2 7.5 9.5 12.6 33.7 12.7 8.0 15.6 8.0 21.0 8.5 5.3 10.0 5.6 13.1 31.4 3.9 25.9 4.5 25.8 10.3 17.0 5.3 13.9 5.1 2.5 9.2 28.9 8.7 14.1 8.6 1.2 10.2 7.5 7.2 18.7 9.2 7.3 6.6 8.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 6.8 0.0 0.0 0.0 5.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 3.6 0.0 9.7 0.0 0.0 18.5 0.0 0.0 0.0 0.2 4.1 0.0 3.0 12.1 14.2 2.5 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.2 0.0 2.3 0.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.1 8.2 10.1 11.5 0.0 1.0 10.1 24.1 2.8 14.0 12.7 8.0 5.3 10.0 4.5 8.7 10.2 8.5 38.4 9.6 56.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 37.4 24.9 0.0 0.0 6.8 11.0 0.0 0.4 1.7 0.0 19.6 21.8 0.0 5.5 9.7 10.9 0.0 0.0 0.0 2.0 0.3 8.3 0.0 15.2 3.8 3.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 12.9 2.2 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 0.0 GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 20.2;Ductal cells: 22.9;Glandular and luminal cells: 15.5;Proximal tubular cells: 22.2;Smooth muscle cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 13 "monocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 46.0;Karpas-707: 23.7;MOLT-4: 29.9;RPTEC TERT1: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010890, HPA020870" Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB010890: AB_259911, HPA020870: AB_1850444" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (3.55e-2)" "unprognostic (9.10e-3)" "unprognostic (4.69e-2)" "unprognostic (1.41e-2)" "unprognostic (6.88e-2)" "unprognostic (6.69e-3)" "unprognostic (3.03e-3)" "unprognostic (1.47e-1)" "unprognostic (8.37e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (7.35e-3)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" 13.8 7.1 23.6 15.6 30.0 2.2 10.0 5.3 36.6 12.6 0.0 28.9 5.8 16.4 6.0 8.1 13.7 13.3 18.7 30.1 28.2 13.2 7.7 16.5 10.4 9.8 13.9 5.8 10.9 50.3 6.0 43.6 22.8 13.6 8.7 34.7 5.5 12.2 5.9 3.5 11.1 25.0 6.4 11.0 13.8 2.4 14.8 7.2 7.3 14.9 7.3 10.0 11.1 17.0 0.0 0.5 6.5 0.0 2.2 11.4 0.0 2.0 3.6 0.2 0.1 0.0 0.0 0.0 3.0 1.1 5.0 0.1 13.6 0.3 0.8 0.0 4.6 46.0 0.0 0.0 1.2 0.0 0.0 5.1 0.4 0.0 0.2 4.2 0.1 10.2 0.0 23.7 3.0 2.1 29.9 0.1 0.4 0.0 3.2 3.5 0.9 0.7 42.9 4.4 0.7 7.8 0.0 0.2 0.0 6.4 0.0 0.0 0.0 7.3 1.6 12.4 9.5 0.3 0.0 0.0 15.6 0.0 0.0 1.4 0.5 0.5 0.0 7.2 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.0 0.5 1.3 23.9 1.6 0.0 5.8 23.6 30.0 5.3 36.6 30.1 28.2 9.8 13.9 22.8 6.4 14.8 17.0 20.2 6.4 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 2.2 0.0 0.0 0.0 9.2 0.0 1.1 1.1 0.0 5.9 22.9 0.0 3.7 4.3 3.4 0.0 0.0 0.0 4.2 0.2 5.4 0.0 15.5 1.3 4.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.7 0.4 0.7 0.0 0.0 GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 136.5;Inhibitory neurons: 115.5;Muller glia cells: 129.4;Syncytiotrophoblasts: 204.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.9;SH-SY5Y: 83.4;WM-115: 228.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020587: AB_1850452" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (3.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (9.28e-2)" "unprognostic (8.25e-3)" "unprognostic (2.23e-1)" "prognostic favorable (4.25e-6)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.29e-1)" "unprognostic (7.33e-2)" "unprognostic (3.04e-4)" 9.4 24.5 2.0 5.8 6.4 0.2 13.1 0.0 4.3 27.7 33.0 13.3 13.5 35.3 83.0 19.2 18.2 17.5 5.2 3.6 7.3 21.3 0.8 13.3 1.7 22.7 4.1 31.8 22.2 26.1 3.4 19.7 23.2 27.7 7.8 17.7 16.1 28.1 9.6 6.2 15.8 21.7 0.3 5.9 22.6 28.0 4.0 1.7 7.8 16.7 3.3 11.9 14.3 0.1 12.5 26.9 106.9 23.8 17.1 15.5 18.6 16.5 27.0 25.1 19.9 18.9 62.6 0.0 13.2 13.2 28.2 8.3 20.0 1.5 18.9 0.0 13.9 27.0 20.5 0.2 15.1 0.0 0.2 10.1 4.2 13.0 14.2 42.9 12.7 0.0 22.5 0.5 19.3 1.8 0.0 0.4 27.4 18.1 46.0 0.1 25.1 14.0 60.0 4.7 0.5 83.4 0.0 14.6 40.2 47.9 4.7 0.1 5.9 7.8 3.8 26.3 9.6 0.0 0.1 0.0 4.6 0.0 228.6 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 6.4 0.0 4.3 3.6 7.3 22.7 4.1 23.2 0.3 4.0 0.1 22.8 16.0 13.4 43.4 1.6 15.7 23.9 3.6 10.2 1.5 10.6 12.2 1.6 45.8 28.2 23.9 0.0 41.1 0.6 3.7 45.0 33.0 5.0 23.9 35.4 32.1 136.5 0.0 82.7 38.2 5.9 55.3 39.8 52.1 0.0 2.2 10.0 1.5 3.2 1.7 115.5 4.6 14.2 1.0 10.5 7.9 20.5 2.0 35.6 53.4 1.1 129.4 0.0 3.0 3.1 51.3 9.8 61.3 1.4 79.8 30.8 43.2 43.5 3.7 6.6 42.2 27.9 79.6 23.9 38.9 27.6 204.4 2.7 27.0 4.7 34.5 GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Endometrial stromal cells: 45.4;Fibroblasts: 23.0;Late spermatids: 27.1;Oligodendrocytes: 61.3;Skeletal myocytes: 40.0;Theca cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 22.3;JURKAT: 22.1;MOLT-4: 36.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: AB_2685988" "unprognostic (9.43e-2)" "unprognostic (8.87e-3)" "unprognostic (1.90e-1)" "unprognostic (4.77e-2)" "unprognostic (3.33e-2)" "unprognostic (7.04e-2)" "unprognostic (4.79e-3)" "unprognostic (5.29e-2)" "unprognostic (5.25e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (3.22e-3)" "unprognostic (4.70e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.42e-5)" 6.0 3.8 2.6 5.2 5.3 1.8 4.0 4.3 3.2 5.7 2.6 3.7 0.6 5.6 2.5 3.2 5.1 10.1 13.6 2.0 2.4 0.9 0.3 3.8 1.5 6.2 5.8 16.5 4.2 2.4 1.9 4.0 4.1 3.3 2.0 0.4 5.3 4.0 0.8 1.7 1.2 5.5 5.3 0.7 1.3 5.8 4.6 6.7 8.8 1.5 1.0 5.7 3.6 6.9 0.2 1.8 0.1 11.2 9.9 19.3 1.7 1.8 4.2 4.0 9.8 0.5 1.2 0.0 3.1 4.9 22.3 0.1 1.0 2.2 3.8 0.0 1.3 0.0 7.2 12.4 12.6 4.9 0.0 18.8 1.1 9.7 1.6 6.0 0.0 22.1 5.8 0.1 2.4 2.7 36.5 0.1 6.6 0.1 2.2 0.2 9.5 0.0 1.3 1.7 1.1 5.0 9.8 0.5 1.3 2.0 3.7 1.5 0.1 4.3 13.5 13.3 6.5 1.0 0.1 0.2 11.1 2.3 7.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.3 0.0 2.6 5.3 4.3 3.2 2.0 2.4 6.2 5.8 4.1 5.3 4.6 6.9 1.6 3.2 2.6 7.2 0.1 1.9 1.9 5.3 0.0 0.6 1.5 7.6 14.6 2.8 2.3 0.0 0.0 0.2 1.5 1.4 0.0 0.1 47.9 5.7 45.4 0.6 3.5 0.0 8.3 1.1 0.3 23.0 0.0 7.5 0.0 8.0 0.7 0.0 0.4 0.0 9.0 2.9 0.0 0.0 4.0 27.1 8.1 0.5 0.0 12.2 0.0 2.5 0.0 3.0 61.3 0.8 0.4 7.2 0.0 2.0 0.6 0.5 2.1 0.4 0.0 40.0 3.9 2.5 4.2 0.2 0.4 0.8 0.4 22.9 1.6 0.4 HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 209.8;Proximal enterocytes: 236.8;Proximal tubular cells: 162.7" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cell line enhanced" "Detected in some" "CACO-2: 14.0;Hep G2: 49.4;REH: 9.9;THP-1: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" 8.7 5.4 1.8 5.9 2.1 4.1 12.9 2.1 2.5 16.0 3.3 13.2 23.1 10.5 14.5 6.0 10.6 6.1 7.0 1.8 2.3 41.8 295.8 5.7 6.1 2.0 2.5 14.0 26.3 2.9 4.5 8.5 2.3 10.1 11.6 0.3 3.8 11.3 2.4 5.0 40.8 4.7 2.1 5.4 9.6 1.8 2.1 4.0 5.8 3.2 4.5 15.8 9.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 4.6 14.0 0.1 0.0 0.1 0.6 0.0 0.0 4.7 0.0 0.8 0.0 1.4 5.6 0.0 49.4 0.4 1.9 0.1 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 2.6 0.2 0.0 9.9 1.1 0.3 0.0 0.0 0.1 0.0 0.6 1.0 0.0 1.3 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 7.9 17.4 19.2 0.0 10.5 0.0 3.5 0.0 0.0 23.2 3.9 0.0 0.1 5.5 0.7 2.9 7.7 0.0 5.6 1.8 2.1 2.1 2.5 1.8 2.3 2.0 2.5 2.3 2.1 2.1 2.3 2.5 0.0 1.1 3.6 3.5 4.0 6.3 2.3 14.8 0.1 2.9 7.6 0.6 14.3 1.6 1.8 0.0 1.1 2.9 18.3 17.6 7.4 0.0 0.6 8.1 1.9 6.7 12.0 3.4 13.3 0.5 18.0 1.5 0.3 30.4 1.2 4.6 209.8 21.3 0.0 2.2 14.9 0.0 13.5 4.9 0.2 12.5 8.7 5.4 8.4 8.4 3.6 1.0 5.5 1.0 4.8 28.7 10.5 0.5 2.1 236.8 162.7 0.5 0.3 13.1 37.7 13.8 0.4 0.7 6.0 4.8 1.2 1.2 2.2 25.5 2.7 HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.3" "Group enriched" "Detected in many" 10 "Early spermatids: 224.6;Late spermatids: 808.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA055969: AB_2682991, HPA062366: " "unprognostic (1.67e-1)" "unprognostic (7.99e-2)" "unprognostic (2.12e-3)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.63e-2)" "unprognostic (3.49e-1)" "unprognostic (2.42e-2)" "unprognostic (1.75e-3)" "unprognostic (1.36e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.25e-1)" "unprognostic (1.40e-1)" "unprognostic (4.93e-2)" "unprognostic (3.62e-2)" 21.9 12.8 62.7 7.0 70.1 1.8 16.8 55.1 73.3 16.1 40.8 19.2 3.0 13.5 7.0 7.6 13.5 8.8 28.1 62.3 63.9 27.0 7.6 10.8 8.3 66.2 65.4 15.6 6.6 12.9 22.6 3.5 66.1 12.5 4.2 16.0 6.2 11.1 16.8 9.5 10.4 9.7 59.5 7.5 12.5 43.9 61.3 4.6 13.7 13.4 5.3 18.4 13.0 68.9 14.8 16.6 20.6 22.3 44.7 37.9 14.6 19.5 21.8 14.5 15.7 24.9 24.0 7.5 9.4 29.4 45.9 10.6 17.4 3.7 11.6 9.0 10.3 2.9 7.8 42.0 22.7 0.7 3.0 15.5 6.7 16.5 13.0 21.9 10.4 8.4 3.4 21.6 26.4 15.2 0.3 4.6 9.6 20.5 15.8 7.6 17.9 0.3 24.8 6.4 13.0 8.8 10.6 6.2 32.5 15.2 4.5 3.2 17.8 19.8 4.6 36.6 16.8 13.2 14.0 3.3 15.9 5.9 29.8 0.0 0.0 0.0 0.5 0.1 0.5 1.9 1.6 1.3 0.0 1.1 1.1 1.1 0.1 0.4 0.3 0.0 1.3 0.2 62.7 70.1 55.1 73.3 62.3 63.9 66.2 65.4 66.1 59.5 61.3 68.9 22.2 0.0 7.4 27.1 5.9 11.5 10.8 0.9 4.0 22.6 3.8 6.9 11.0 14.3 5.5 18.4 0.0 2.5 5.5 0.9 17.6 4.7 224.6 7.3 9.0 14.6 13.1 0.8 47.4 5.8 7.4 13.3 1.5 8.1 1.3 13.0 15.0 6.3 6.6 23.5 33.2 0.9 4.1 1.3 9.3 808.8 13.7 6.0 17.8 10.3 2.7 22.2 3.1 18.6 37.5 6.3 0.0 23.7 5.1 10.0 1.1 43.7 1.8 15.6 6.6 5.8 26.4 26.8 15.4 0.9 8.0 1.4 13.3 3.0 1.3 6.0 HCFC1R1 "FLJ20568, HPIP" ENSG00000103145 "Host cell factor C1 regulator 1" Q9NWW0 16 3022625-3024286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 511.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 396.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 376.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059647 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA059647: AB_2684094" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.85e-3)" "unprognostic (6.03e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (1.61e-2)" "unprognostic (2.12e-1)" "unprognostic (3.43e-3)" "unprognostic (2.23e-1)" "unprognostic (2.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (4.89e-2)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.23e-1)" 82.6 98.5 174.5 20.9 178.9 17.9 74.8 164.1 248.1 124.9 129.3 131.5 30.4 140.6 29.2 59.0 81.7 43.1 138.7 172.0 182.0 180.5 48.2 72.0 24.2 181.5 182.7 86.7 44.0 40.9 97.7 32.1 185.2 102.8 18.8 21.6 50.6 87.4 511.6 76.3 53.1 47.5 154.0 45.9 65.6 36.6 181.0 17.0 68.0 196.2 18.3 85.2 103.0 174.1 59.6 175.6 32.5 38.1 123.0 160.9 33.4 26.0 115.0 57.8 161.2 37.9 75.8 49.2 66.1 108.3 52.8 81.0 32.7 121.5 26.3 62.7 88.4 21.3 132.2 65.5 105.2 37.3 39.5 205.7 73.9 62.1 63.4 376.5 81.5 33.0 30.4 81.6 63.3 63.0 20.1 53.0 70.5 34.7 36.5 70.1 31.3 124.6 209.4 13.7 57.3 48.4 54.7 70.7 78.5 77.5 48.6 28.1 35.5 98.4 256.8 85.8 50.7 53.0 59.1 40.7 42.9 22.1 23.8 5.3 36.3 16.3 20.1 28.2 19.3 23.2 25.5 21.7 44.9 21.7 18.5 22.9 8.0 25.8 26.5 22.1 36.7 17.9 174.5 178.9 164.1 248.1 172.0 182.0 181.5 182.7 185.2 154.0 181.0 174.1 51.3 57.7 15.0 17.9 30.7 85.4 58.0 123.7 92.2 29.3 45.2 80.0 45.8 47.1 37.4 198.6 6.2 116.2 23.7 53.7 240.7 49.7 5.2 38.0 56.0 38.3 43.7 37.0 19.3 26.5 120.7 98.4 34.1 45.3 40.0 26.1 60.3 45.9 117.9 20.2 19.8 40.9 40.7 57.5 57.0 15.8 96.3 42.2 64.0 13.1 51.0 52.6 39.1 6.6 19.0 26.7 55.4 178.3 35.0 37.8 114.2 396.2 28.4 28.1 124.9 39.7 149.2 15.2 44.3 69.5 65.8 53.9 35.0 26.7 45.9 41.3 HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162549-66268867 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.9;smooth muscle: 82.7" "Cell type enhanced" "Detected in many" "Astrocytes: 78.0;Distal enterocytes: 211.0;Intestinal goblet cells: 95.6;Paneth cells: 96.9;Proximal enterocytes: 156.2;Undifferentiated cells: 72.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 28.5;HEL: 25.4;HSkMC: 36.0;K-562: 72.5;LHCN-M2: 28.5;SuSa: 68.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" 8.2 19.1 18.2 14.7 25.0 0.0 8.3 20.8 19.2 23.8 8.7 81.9 79.0 34.7 14.4 11.9 14.2 38.7 36.0 16.7 21.2 8.1 3.5 12.3 3.6 22.3 24.4 22.1 2.3 1.4 3.7 1.3 20.4 24.3 77.6 15.0 7.6 31.8 0.8 4.8 81.6 82.7 18.8 11.1 12.4 3.5 21.7 1.3 5.1 3.2 2.6 19.5 10.1 21.0 0.0 0.0 28.5 2.3 0.0 0.1 0.8 7.3 0.4 0.0 0.0 17.4 0.0 0.0 0.1 15.1 0.0 0.0 0.0 0.0 0.0 8.3 0.0 25.4 0.0 0.0 0.3 0.2 0.1 36.0 0.0 0.0 0.0 9.9 0.0 0.0 72.5 0.6 28.5 0.0 0.0 0.6 14.1 4.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 68.6 0.0 0.0 0.7 16.2 1.2 0.1 1.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 25.0 20.8 19.2 16.7 21.2 22.3 24.4 20.4 18.8 21.7 21.0 2.5 0.0 0.0 78.0 0.5 0.9 0.0 0.0 0.0 1.0 0.9 6.0 24.1 0.0 0.0 0.0 0.0 0.0 0.1 211.0 0.0 0.3 0.6 1.3 15.1 4.1 40.8 0.0 0.3 1.1 0.0 12.6 0.0 1.2 0.0 1.1 6.4 0.0 0.2 0.0 2.9 95.6 0.0 0.0 1.9 1.5 11.5 0.3 0.0 6.5 0.0 26.1 0.0 3.5 36.2 5.0 96.9 29.7 0.0 0.3 156.2 0.0 0.7 1.3 6.6 4.4 9.8 0.0 0.3 0.3 0.6 0.0 0.5 6.9 72.4 0.2 HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;lung: 16.2" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 175.6;Leydig cells: 136.1;Oligodendrocytes: 413.3;Theca cells: 162.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 322.6;TIME: 376.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Approved Nucleoplasm "Secreted in other tissues" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" 2.3 2.3 10.4 0.4 25.4 0.8 0.3 10.7 19.6 1.3 0.0 3.2 2.6 1.6 3.8 0.0 0.1 1.1 0.2 17.1 11.0 0.8 6.8 16.2 0.0 20.0 20.2 0.6 2.6 0.0 0.3 0.0 13.6 4.7 3.2 0.9 0.3 2.6 0.4 0.2 3.7 0.1 9.4 0.0 5.9 1.5 18.1 2.7 0.6 1.3 0.0 5.0 0.3 37.3 0.0 0.1 4.9 0.1 0.3 1.9 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 3.0 0.2 0.3 0.0 2.2 0.0 2.0 0.1 0.0 0.1 0.1 0.0 0.0 10.4 7.8 17.2 322.6 29.1 0.1 0.0 4.8 0.0 47.7 0.0 4.4 0.0 2.8 0.4 65.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 376.7 0.4 3.9 0.3 2.5 2.2 0.0 10.1 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 10.4 25.4 10.7 19.6 17.1 11.0 20.0 20.2 13.6 9.4 18.1 37.3 0.3 12.8 175.6 3.9 0.4 0.0 0.0 0.5 0.0 42.7 0.0 0.0 1.2 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.5 6.0 0.6 0.0 0.0 17.6 0.4 0.0 38.9 0.0 0.4 16.5 0.1 9.3 0.1 0.1 0.0 13.9 0.0 2.0 0.0 0.4 4.5 136.1 1.3 1.8 1.0 0.0 0.3 0.0 8.5 413.3 0.1 0.0 44.0 0.0 0.0 0.0 0.0 4.4 3.3 0.0 1.7 0.9 0.3 0.5 0.0 0.6 0.0 1.0 162.7 0.0 0.0 HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in some" "Astrocytes: 33.3;Bipolar cells: 10.5;Excitatory neurons: 8.3;Inhibitory neurons: 12.2;Muller glia cells: 13.1;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;fHDF/TERT166: 5.6;SiHa: 3.7;THP-1: 3.9" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA 120000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" 1.6 0.3 7.0 1.1 8.7 0.1 0.8 4.1 8.4 1.5 3.0 2.0 0.5 2.5 0.4 0.8 1.3 1.2 1.6 7.2 4.6 0.7 0.6 0.7 1.0 4.9 4.7 1.0 0.2 0.3 0.9 0.6 4.5 1.7 0.3 2.1 0.8 0.9 0.3 0.5 0.9 1.8 4.0 0.9 0.8 0.4 6.3 0.1 0.5 0.4 0.6 1.3 1.1 4.2 0.0 0.2 0.4 0.1 0.1 0.0 1.7 1.6 0.4 0.3 0.1 0.1 0.5 0.1 3.1 5.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.7 0.0 0.0 0.9 0.1 1.2 0.2 0.1 1.4 0.1 0.0 0.1 0.9 0.2 0.0 0.2 1.2 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.6 3.7 0.0 0.0 0.6 0.0 3.9 1.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 8.7 4.1 8.4 7.2 4.6 4.9 4.7 4.5 4.0 6.3 4.2 1.6 0.0 0.0 33.3 0.1 0.0 0.0 0.0 0.0 10.5 0.3 0.8 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 2.0 1.7 0.0 0.0 8.3 0.0 0.1 2.6 0.0 0.0 0.0 0.9 0.7 0.3 1.9 0.0 12.2 0.0 0.0 2.1 0.7 0.2 0.3 0.3 3.6 6.5 0.0 13.1 0.0 13.0 6.2 0.0 1.4 1.9 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.9 0.9 0.3 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.1 HIC1 "ZBTB29, ZNF901" ENSG00000177374 "HIC ZBTB transcriptional repressor 1" Q14526 17 2054154-2063241 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 38.6;Fibroblasts: 44.3;Leydig cells: 57.5;Peritubular cells: 48.2;Sertoli cells: 46.0;Smooth muscle cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.9;BJ: 11.9;HSkMC: 7.1;TIME: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043372 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043372: AB_10795614" "unprognostic (1.93e-1)" "unprognostic (9.27e-2)" "unprognostic (6.63e-2)" "unprognostic (4.27e-3)" "unprognostic (2.06e-1)" "unprognostic (1.87e-2)" "unprognostic (3.08e-1)" "unprognostic (6.45e-2)" "unprognostic (8.58e-2)" "unprognostic (2.06e-2)" "unprognostic (1.73e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (9.36e-6)" "unprognostic (2.20e-2)" "unprognostic (3.92e-2)" "unprognostic (1.00e-1)" "unprognostic (5.14e-2)" 24.5 8.6 5.0 5.7 4.0 1.3 16.5 3.4 3.8 23.9 2.8 16.1 6.5 27.0 1.5 5.7 21.5 4.4 23.4 3.0 3.1 12.4 5.9 15.2 2.1 5.7 4.5 30.0 3.8 0.9 19.7 1.4 4.1 20.1 1.7 0.5 5.2 4.5 8.5 5.3 11.7 3.2 3.9 8.9 9.8 4.9 5.6 2.3 12.6 1.2 0.5 17.9 13.9 2.4 0.6 0.7 0.8 0.6 4.7 6.9 1.4 11.9 6.4 1.6 2.3 0.6 0.3 0.1 0.2 6.2 0.6 1.1 0.7 0.2 0.5 0.4 1.5 0.3 0.8 0.3 4.0 0.2 0.5 7.1 0.8 2.4 0.1 3.3 6.2 0.6 1.8 2.8 0.4 0.0 0.1 0.4 0.2 0.0 0.4 0.7 0.3 0.3 0.2 0.4 0.4 0.7 0.2 0.1 0.0 0.2 0.0 0.1 12.4 4.3 0.1 4.2 6.2 0.4 0.4 0.2 0.4 0.4 1.1 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 4.0 3.4 3.8 3.0 3.1 5.7 4.5 4.1 3.9 5.6 2.4 25.6 0.0 1.8 1.0 3.9 4.0 2.1 1.5 1.2 2.1 1.9 1.8 5.8 0.0 1.0 1.8 0.0 0.1 19.2 0.1 0.0 0.5 0.5 2.0 38.6 26.9 1.8 0.4 0.2 1.1 0.7 44.3 1.1 1.6 2.5 0.2 23.9 0.3 0.5 0.0 0.3 0.1 2.0 8.5 6.0 1.6 57.5 15.5 3.6 6.5 0.2 0.3 12.3 0.0 0.0 0.2 0.1 48.2 2.3 1.1 0.2 0.1 1.0 1.6 46.0 12.5 30.1 0.8 2.9 1.1 4.1 0.1 13.0 13.3 0.0 2.6 HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.8;Endothelial cells: 21.4;Fibroblasts: 22.2;Horizontal cells: 26.9;Microglial cells: 45.0" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 22.3;hTERT-RPE1: 20.1;MCF7: 76.5;SK-MEL-30: 50.2;WM-115: 43.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" 9.7 1.4 1.3 0.6 1.2 0.0 8.4 0.9 1.1 3.7 1.3 9.0 0.9 1.9 2.5 5.4 1.8 6.5 8.4 0.8 1.1 2.5 7.8 20.3 0.4 1.5 1.9 3.9 0.9 0.9 3.2 4.8 1.5 7.5 2.8 0.6 7.7 1.4 4.8 4.1 3.1 4.3 1.4 8.4 1.7 2.6 1.7 0.8 3.2 7.0 2.4 1.8 3.8 0.9 0.2 0.1 1.6 0.0 4.7 4.7 0.0 0.5 0.9 0.3 0.5 0.0 0.1 1.9 0.2 22.3 1.6 5.0 0.1 0.2 0.1 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.7 0.0 5.6 0.4 20.1 2.8 0.0 0.2 0.0 0.0 76.5 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 50.2 4.5 0.1 0.0 0.0 13.7 1.3 0.0 5.1 0.2 0.0 0.3 2.7 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 1.2 0.9 1.1 0.8 1.1 1.5 1.9 1.5 1.4 1.7 0.9 33.8 3.2 7.0 0.3 0.0 3.2 0.2 4.9 2.2 1.7 1.2 1.8 2.8 0.0 0.8 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.3 0.6 1.5 21.4 0.0 0.0 1.1 0.0 0.8 22.2 0.0 0.9 0.0 5.2 7.9 1.9 0.1 26.9 3.8 0.0 0.0 0.3 2.8 2.7 3.7 0.4 5.4 45.0 0.0 0.1 0.0 3.0 1.5 0.0 0.0 2.2 1.2 0.1 0.0 0.2 1.0 0.0 0.0 2.5 7.7 0.5 0.1 0.4 1.7 0.0 0.4 0.1 0.0 0.2 HMGCLL1 "bA418P12.1, DKFZP434G1411" ENSG00000146151 "3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1" Q8TB92 6 55434373-55579197 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in some" "Astrocytes: 49.9;Excitatory neurons: 80.7;Inhibitory neurons: 76.2;Oligodendrocytes: 23.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.74e-3)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (6.11e-2)" "unprognostic (1.41e-1)" "unprognostic (9.54e-3)" "unprognostic (8.97e-3)" "unprognostic (2.12e-2)" "unprognostic (9.27e-3)" "unprognostic (4.11e-2)" "unprognostic (1.18e-4)" "unprognostic (3.13e-3)" "unprognostic (7.57e-2)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" 1.4 3.6 6.1 0.2 5.9 0.0 1.4 5.9 5.2 0.8 0.0 0.8 0.2 0.2 0.0 1.0 0.4 0.6 1.8 5.5 10.6 0.9 0.7 2.6 0.3 5.6 6.3 0.4 1.6 0.1 4.7 6.2 6.6 3.0 0.8 4.5 0.8 1.0 1.1 0.1 0.9 0.5 9.2 0.0 1.0 2.6 8.3 0.6 0.4 2.8 0.2 0.9 0.7 9.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.2 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.9 5.9 5.2 5.5 10.6 5.6 6.3 6.6 9.2 8.3 9.4 0.6 0.0 1.3 49.9 0.0 0.0 0.0 0.0 1.2 15.1 3.7 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.5 0.0 0.0 80.7 0.0 0.0 5.8 0.0 0.0 0.0 3.5 3.9 0.0 0.1 0.0 76.2 0.0 0.0 0.3 0.0 1.3 0.3 0.1 0.0 15.0 0.0 1.5 0.0 5.5 23.5 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.9 5.6 1.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 HOXA4 "HOX1, HOX1D" ENSG00000197576 "Homeobox A4" Q00056 7 27128507-27130780 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 11.6;Basal squamous epithelial cells: 31.9;Distal tubular cells: 15.6;Hepatic stellate cells: 16.8;Proximal tubular cells: 13.1;Squamous epithelial cells: 12.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 10 "medulla oblongata: 19.3;pons: 16.1;spinal cord: 15.6;white matter: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.0;HEK 293: 22.2;REH: 21.0;WM-115: 29.1" "Region enriched" "Detected in single" 46 "pons and medulla: 11.3" HPA060088 Approved Supported "Nuclear bodies" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA060088: AB_2684200" "unprognostic (3.37e-2)" "unprognostic (6.27e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.32e-1)" "unprognostic (4.22e-1)" "unprognostic (1.31e-1)" "unprognostic (7.39e-2)" "unprognostic (4.23e-1)" "unprognostic (5.63e-2)" "unprognostic (2.65e-2)" "unprognostic (3.38e-1)" "unprognostic (3.59e-4)" "unprognostic (3.93e-2)" 16.2 10.0 0.0 2.1 0.0 0.7 10.5 0.1 0.1 5.5 0.0 13.2 4.9 5.9 13.0 15.3 22.1 3.6 1.9 0.0 0.0 16.3 1.5 14.7 1.3 19.3 1.6 6.8 1.9 25.8 0.0 0.1 16.1 5.9 2.4 0.0 0.6 5.8 18.8 4.9 8.2 4.6 15.6 6.9 13.4 1.6 0.0 1.9 3.7 8.2 0.4 7.7 4.6 14.1 9.5 3.1 0.0 29.0 0.0 0.0 1.9 0.9 0.9 3.0 3.0 5.9 1.9 2.5 0.1 2.8 2.7 4.0 1.1 0.4 2.3 0.1 22.2 0.0 0.9 13.7 3.3 3.3 5.4 3.2 2.4 10.2 0.8 0.0 10.3 0.8 0.0 0.0 10.0 2.5 0.0 11.2 0.0 3.3 7.2 21.0 4.4 0.2 14.6 2.2 1.4 0.0 2.9 0.0 11.2 1.0 0.7 1.7 13.5 0.0 4.6 7.6 0.2 0.0 0.0 1.0 6.1 5.1 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 19.3 1.6 16.1 15.6 0.0 14.1 11.6 0.0 0.0 0.0 0.1 0.9 3.1 0.0 31.9 0.0 3.6 7.7 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.7 15.6 0.0 0.4 0.2 2.6 5.2 3.0 0.8 0.0 0.0 0.9 5.4 0.5 0.1 0.0 0.4 16.8 0.0 0.2 0.0 0.0 0.9 0.0 0.6 0.3 0.4 0.0 0.9 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.7 1.4 0.7 1.0 13.1 0.0 0.0 0.0 8.3 5.8 0.4 3.2 12.5 1.3 0.1 0.8 1.4 2.0 2.5 HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.6;endometrium 1: 35.9;vagina: 25.0" "Cell type enhanced" "Detected in some" "Adipocytes: 13.0;Collecting duct cells: 14.7;Distal enterocytes: 10.6;Distal tubular cells: 15.6;Endometrial stromal cells: 25.3;Endothelial cells: 13.5;Enteroendocrine cells: 24.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 12.0;HEK 293: 40.3;RPTEC TERT1: 32.3;SCLC-21H: 11.8;SiHa: 18.4;U-251 MG: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 66 "spinal cord: 6.6" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: AB_2685573" "unprognostic (4.29e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (6.82e-2)" "unprognostic (1.04e-5)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (2.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.86e-1)" "unprognostic (1.27e-1)" 2.0 0.1 0.0 0.5 0.0 0.0 2.6 0.0 0.0 20.6 0.0 18.7 0.0 35.9 0.5 0.5 4.1 0.1 0.0 0.0 0.0 19.9 0.0 0.1 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 16.8 5.8 0.0 0.1 6.7 0.1 1.5 0.1 18.1 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.2 2.2 25.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.2 6.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.1 12.0 0.0 0.0 0.5 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 32.3 0.0 11.8 3.1 18.4 0.0 0.1 2.2 0.0 0.0 2.7 0.0 2.1 1.0 14.4 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.9 6.2 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 14.7 0.0 0.0 0.1 10.6 15.6 0.0 0.0 1.2 25.3 13.5 24.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.8 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.1 1.1 0.0 0.2 0.0 4.4 2.9 HOXD9 "HOX4, HOX4C" ENSG00000128709 "Homeobox D9" P28356 2 176122719-176124937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 42.2;endometrium 1: 57.8;kidney: 52.1" "Cell type enhanced" "Detected in many" "Adipocytes: 38.4;Collecting duct cells: 23.9;Distal tubular cells: 37.2;Endothelial cells: 39.2;Leydig cells: 34.2;Peritubular cells: 26.7;Sertoli cells: 39.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 11.3;HEK 293: 16.1;RPTEC TERT1: 19.0;SH-SY5Y: 21.7;SK-MEL-30: 13.2;TIME: 16.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 80 "spinal cord: 8.0" HPA068683 Supported Nucleoplasm,Nucleoli NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" "HPA068683: AB_2686018" "unprognostic (1.89e-1)" "unprognostic (9.41e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.03e-2)" "prognostic favorable (9.58e-4)" "prognostic unfavorable (1.08e-5)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-3)" "unprognostic (6.71e-2)" "unprognostic (4.77e-3)" "unprognostic (8.38e-2)" "unprognostic (5.94e-2)" "unprognostic (1.89e-1)" "unprognostic (9.44e-2)" 11.6 6.4 0.0 1.3 0.0 0.0 13.9 0.0 0.0 42.2 0.0 29.3 0.1 57.8 14.8 3.5 16.1 0.9 0.2 0.0 0.0 52.1 0.1 0.7 2.4 0.5 0.0 11.1 0.3 0.3 0.0 0.5 0.1 32.3 2.9 0.0 1.2 8.0 1.6 5.8 3.0 15.2 0.5 2.4 0.5 5.6 0.1 0.5 1.4 0.2 0.8 6.1 35.3 0.8 0.1 0.0 0.0 0.0 0.5 0.4 0.2 1.6 1.1 1.3 1.1 0.0 0.0 0.0 11.3 1.6 0.8 7.6 0.1 0.0 0.9 0.0 16.1 0.0 0.8 0.0 0.1 0.0 0.0 3.6 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 19.0 7.1 4.3 21.7 5.5 0.0 13.2 1.1 0.0 0.0 16.9 0.0 3.6 5.3 6.0 0.0 0.0 0.0 1.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.5 0.1 0.8 38.4 0.0 0.0 0.0 0.4 2.4 1.9 0.0 0.0 0.0 0.8 0.5 0.7 0.0 0.0 23.9 0.0 0.0 1.0 8.5 37.2 0.0 0.2 0.8 10.9 39.2 7.8 0.0 0.0 0.0 0.2 1.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.0 3.0 1.3 34.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 26.7 0.0 1.1 0.0 3.0 0.0 0.0 39.5 1.9 3.3 2.2 1.4 0.1 1.8 0.0 1.1 13.9 3.8 0.8 HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Steroidogenesis Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 136.5" "Cell type enhanced" "Detected in many" "Ductal cells: 42.5;Hepatocytes: 68.9;Hofbauer cells: 53.9;Proximal enterocytes: 45.3;Proximal tubular cells: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.8;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.8" "Cell line enhanced" "Detected in many" "HDLM-2: 91.0;Hep G2: 66.2;HMC-1: 98.1;U-2197: 96.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" 27.3 25.7 5.7 10.9 6.2 4.4 17.1 14.7 9.1 8.5 3.5 15.9 19.5 9.5 2.1 12.3 9.4 11.5 11.7 5.9 5.9 27.7 136.5 11.2 8.4 6.3 5.4 8.6 25.6 8.0 5.4 4.5 6.6 8.2 5.8 1.6 10.0 4.5 7.0 18.5 18.4 9.8 5.6 16.3 11.1 6.0 7.1 2.8 6.3 4.5 5.5 13.9 8.7 6.9 20.3 23.2 2.4 11.5 7.9 28.5 1.4 24.8 38.7 4.8 10.0 1.7 34.4 1.2 8.1 30.3 0.8 6.1 2.2 3.6 2.4 91.0 5.4 1.6 18.6 66.2 7.4 0.5 98.1 13.7 6.0 23.1 4.6 11.2 2.2 1.2 4.9 1.0 18.3 43.6 0.6 14.4 1.9 8.5 3.2 2.5 7.8 22.3 15.1 1.3 8.4 4.1 3.2 15.9 2.2 1.1 31.1 1.6 11.5 10.0 2.8 96.1 2.7 1.6 15.4 1.1 39.1 2.5 0.8 61.8 1.4 27.3 0.1 0.1 0.1 0.1 0.1 0.0 1.6 0.2 0.0 0.1 1.2 0.5 0.0 0.6 0.0 0.7 5.7 6.2 14.7 9.1 5.9 5.9 6.3 5.4 6.6 5.6 7.1 6.9 7.6 3.2 4.2 3.3 1.2 7.9 2.6 4.1 4.0 0.7 13.6 9.8 1.7 27.1 2.2 14.7 0.0 2.0 0.5 10.8 15.6 42.5 37.5 1.9 7.1 11.1 7.8 4.8 0.2 30.3 3.5 26.0 8.2 4.2 9.5 9.0 6.8 68.9 53.9 1.7 0.4 11.4 6.1 7.3 15.9 2.2 6.5 11.4 14.2 0.0 12.8 2.1 0.0 0.5 1.2 20.7 14.0 5.3 1.9 1.8 45.3 46.7 1.3 0.5 13.1 9.4 6.3 0.8 1.2 4.9 12.6 1.4 1.7 6.5 23.5 2.8 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 323.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "amygdala: 194.3;basal ganglia: 212.9;cerebral cortex: 323.4;hippocampal formation: 320.5;white matter: 109.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" NA NA 17000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 24: Non-specific - Transcription regulation" "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" 32.7 43.3 194.3 29.5 212.9 47.6 27.9 0.0 323.4 37.5 0.0 35.7 21.1 35.1 43.5 26.1 35.7 26.3 42.2 320.5 25.7 22.7 15.8 40.5 31.0 9.7 9.4 45.4 23.3 57.0 67.8 16.3 3.1 29.4 20.8 48.6 24.7 41.0 25.1 37.1 27.9 30.5 0.2 34.1 23.0 6.1 32.3 17.2 27.2 38.9 36.0 32.8 31.5 109.4 46.4 50.7 19.6 12.7 22.1 40.9 9.2 26.6 67.8 23.3 43.9 10.2 32.7 110.0 69.6 38.3 49.1 22.6 21.3 40.5 30.1 40.8 17.7 11.5 14.7 5.7 17.8 18.8 101.3 21.4 19.6 50.9 33.1 95.5 37.8 20.2 5.7 76.6 34.7 57.9 19.6 9.3 17.5 28.8 34.3 12.4 19.4 20.7 27.8 10.5 28.9 67.6 9.8 22.1 32.0 33.2 6.9 7.9 44.3 29.9 31.3 50.1 70.8 54.5 47.3 79.3 138.0 44.3 22.1 117.5 56.9 171.7 70.9 63.0 53.2 35.2 43.1 54.0 48.7 27.0 28.4 42.9 261.1 37.2 73.9 36.8 74.0 63.0 194.3 212.9 0.0 323.4 320.5 25.7 9.7 9.4 3.1 0.2 32.3 109.4 53.7 99.3 64.4 55.8 150.9 33.1 60.6 44.0 20.5 178.3 43.2 43.8 44.1 27.1 58.9 82.8 45.9 34.2 158.5 66.9 21.5 50.2 1.3 59.8 36.8 44.7 168.4 19.6 232.3 74.0 25.7 78.3 31.1 49.5 226.2 25.5 60.3 33.0 44.0 222.1 243.7 29.0 73.2 94.8 109.8 3.7 72.7 98.4 51.6 63.7 120.9 55.0 146.2 39.2 95.8 85.0 50.3 89.5 98.8 71.3 74.6 22.3 112.4 59.5 59.2 68.1 65.2 3.5 6.6 22.2 43.8 143.0 183.9 16.4 17.1 96.9 IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 63.3;Distal tubular cells: 64.6;Muller glia cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 66.7" "Group enriched" "Detected in all" 8 "granulocytes: 66.7;monocytes: 21.7" "Group enriched" "Detected in many" 5 "BJ hTERT+ SV40 Large T+: 325.3;BJ hTERT+ SV40 Large T+ RasG12V: 318.1" "CAB045980, HPA053890, HPA055380" Approved Enhanced Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB045980: AB_11125836, HPA053890: , HPA055380: AB_2682800" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (7.96e-3)" "unprognostic (1.35e-3)" "unprognostic (2.02e-2)" "unprognostic (6.45e-2)" "unprognostic (3.66e-1)" "unprognostic (3.34e-1)" "unprognostic (8.65e-3)" "unprognostic (1.82e-2)" "unprognostic (7.68e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-2)" "unprognostic (5.95e-2)" "unprognostic (9.75e-3)" "unprognostic (6.40e-3)" 17.5 38.0 12.6 4.5 12.4 9.9 14.3 15.2 17.8 17.2 13.0 14.6 3.9 6.9 6.6 5.0 9.5 13.8 22.7 12.4 12.7 23.7 24.9 14.1 3.4 15.1 14.2 9.1 6.1 11.9 20.3 9.9 13.5 6.7 5.0 8.0 42.0 6.2 17.4 4.9 7.5 7.9 29.4 18.7 6.9 5.4 13.9 13.3 9.1 20.6 2.4 7.6 9.4 14.4 10.0 1.2 2.6 17.2 8.1 16.5 0.2 11.7 68.9 325.3 318.1 1.0 10.4 0.7 3.8 14.6 63.4 8.2 1.0 1.0 15.6 0.6 1.1 1.7 8.4 0.9 9.2 1.4 1.7 13.5 0.3 6.2 0.1 6.4 0.4 1.7 0.2 7.7 3.5 0.3 2.3 6.8 0.3 0.1 6.3 3.1 0.8 2.0 7.9 1.2 0.1 0.6 3.1 2.4 69.6 2.4 1.3 1.5 0.5 1.7 1.9 2.5 1.4 1.0 1.3 0.6 2.2 2.3 0.9 9.9 12.6 15.4 1.6 15.6 2.9 3.0 4.1 2.9 3.7 3.2 5.7 3.5 66.7 1.9 21.7 0.2 4.9 6.6 12.6 12.4 15.2 17.8 12.4 12.7 15.1 14.2 13.5 29.4 13.9 14.4 63.3 35.3 5.8 7.2 2.5 2.9 3.3 12.9 3.4 26.4 2.4 5.2 19.1 4.3 7.6 9.2 18.8 4.8 4.7 6.3 64.6 12.6 0.4 21.1 3.2 41.4 0.0 4.0 13.8 5.1 20.8 22.8 0.5 7.2 2.5 11.0 9.3 12.1 36.9 32.0 13.3 1.4 4.1 14.5 3.3 3.0 19.3 13.3 1.8 16.9 13.5 77.9 1.0 12.1 14.4 3.6 4.7 43.6 0.7 1.1 9.8 26.7 17.8 13.4 39.5 18.1 11.4 0.5 3.0 1.0 1.7 1.4 3.1 15.4 0.2 1.2 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34650702-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 57.8;Late spermatids: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 36.8;HSkMC: 38.2" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652" Supported "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229" "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" 26.6 14.8 20.0 15.5 22.9 13.7 30.2 23.9 23.8 44.6 17.2 58.0 21.7 32.9 12.2 16.3 36.8 19.5 66.4 20.6 20.4 21.9 50.7 22.6 32.0 21.4 21.5 38.0 12.9 29.2 21.8 10.3 20.4 30.3 11.4 18.7 26.1 15.7 30.0 61.3 37.9 19.6 20.8 33.3 26.0 18.3 21.6 16.9 48.0 28.5 21.1 32.2 34.1 22.9 2.5 5.5 11.7 11.7 16.5 28.9 5.5 13.8 19.1 8.8 11.9 2.0 4.6 2.6 3.7 36.8 3.3 5.0 3.4 5.0 3.5 23.8 9.2 7.9 23.4 1.0 8.4 2.7 4.3 38.2 6.1 4.9 1.7 11.9 5.6 16.4 3.3 5.4 11.3 1.6 3.6 18.6 2.5 2.0 3.7 5.6 2.3 2.7 2.9 2.5 3.4 12.3 1.7 3.7 5.3 6.1 10.1 10.2 5.2 4.1 10.0 3.2 0.0 3.7 2.6 1.0 10.9 3.1 20.1 2.1 1.0 0.0 1.4 1.4 2.1 0.8 2.7 2.2 1.3 1.0 2.5 1.8 0.3 1.0 0.3 0.5 1.7 1.7 20.0 22.9 23.9 23.8 20.6 20.4 21.4 21.5 20.4 20.8 21.6 22.9 15.8 3.2 14.3 26.8 2.6 17.5 5.8 3.6 6.2 19.6 6.4 25.1 37.9 1.5 3.6 3.7 14.6 11.3 5.1 3.7 0.0 1.9 18.3 0.7 4.4 15.2 9.1 0.8 4.3 0.7 4.1 42.7 3.1 1.3 0.0 57.8 17.5 32.1 4.6 23.5 9.0 5.0 0.0 3.5 19.6 97.2 11.1 3.6 32.0 4.7 2.6 15.2 6.2 5.0 7.3 0.3 4.3 5.7 2.4 2.9 7.0 2.4 1.4 9.0 0.0 32.9 8.9 4.6 21.6 1.4 14.1 12.4 6.0 12.2 5.2 1.7 IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.8;skeletal muscle: 131.1" "Cell type enhanced" "Detected in many" "Astrocytes: 64.0;Early spermatids: 19.3;Excitatory neurons: 17.5;Late spermatids: 35.0;Muller glia cells: 20.2;Oligodendrocyte precursor cells: 20.6" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 25000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" 8.4 5.7 71.9 1.6 79.7 0.4 6.4 68.7 58.7 15.2 21.6 5.6 9.4 6.5 1.1 8.9 5.0 5.1 11.6 66.0 70.9 2.6 0.8 6.2 1.2 79.1 62.2 9.3 5.9 0.4 8.9 1.6 61.8 5.5 0.5 10.6 4.3 1.6 131.1 5.4 5.7 1.2 79.6 0.9 4.4 3.9 68.2 0.2 7.6 24.5 0.3 5.4 9.9 79.8 16.5 2.2 3.5 7.6 8.1 4.6 18.3 4.5 1.1 0.4 0.8 7.6 8.7 11.0 0.8 0.4 5.3 8.5 1.5 0.1 0.2 4.0 12.2 0.8 0.7 9.1 1.0 12.2 2.4 6.3 0.1 0.6 0.0 6.9 5.0 15.3 4.5 0.0 3.0 15.9 13.6 10.0 10.7 19.2 2.6 17.8 8.6 1.3 0.2 14.1 20.7 6.7 2.6 3.8 18.3 6.1 9.6 10.4 27.1 1.7 3.0 1.4 5.7 2.0 1.7 2.9 4.0 5.7 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.9 79.7 68.7 58.7 66.0 70.9 79.1 62.2 61.8 79.6 68.2 79.8 0.7 0.0 0.0 64.0 0.2 2.4 0.3 0.0 1.2 1.2 0.4 0.4 1.0 0.0 0.0 0.0 0.0 1.1 0.3 0.7 0.0 0.1 19.3 0.2 1.6 0.6 0.0 0.4 17.5 0.2 7.4 7.6 0.0 0.7 0.0 0.9 1.4 0.0 0.4 0.0 12.2 0.1 0.0 0.3 1.9 35.0 11.5 0.2 8.8 2.8 0.0 20.2 0.0 20.6 12.5 0.2 0.1 1.2 0.0 0.5 0.2 0.2 0.0 4.9 0.0 9.4 2.0 8.6 0.6 0.0 2.0 1.1 0.3 0.1 0.3 0.2 IL17RD "FLJ35755, IL-17RD, IL17RLM, SEF" ENSG00000144730 "Interleukin 17 receptor D" Q8NFM7 3 57089982-57170306 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 14.0;Early spermatids: 17.9;Late spermatids: 23.7;Microglial cells: 15.0;Peritubular cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 25.0;AN3-CA: 67.9;NTERA-2: 39.2;SH-SY5Y: 102.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039577, HPA043550" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Nucleoplasm "HPA039577: AB_2676580, HPA043550: AB_2678546" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (2.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-2)" "unprognostic (9.62e-2)" "unprognostic (1.17e-2)" "unprognostic (1.60e-1)" "unprognostic (3.72e-1)" "unprognostic (2.11e-3)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.92e-9)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (2.63e-3)" "unprognostic (9.58e-3)" 1.9 0.8 4.7 0.9 5.7 0.0 7.4 5.2 4.0 6.0 28.0 5.9 0.4 13.5 10.6 2.4 6.4 3.3 1.9 5.5 6.5 5.7 0.2 0.6 0.3 8.9 8.8 7.4 0.9 9.4 2.3 0.3 5.5 5.1 1.8 0.3 6.0 8.5 0.6 2.0 1.0 12.0 6.2 2.5 1.2 9.7 4.8 0.3 0.5 2.6 0.5 2.8 3.3 6.5 4.0 0.8 25.0 67.9 0.1 0.6 4.0 0.4 0.2 0.3 0.8 0.5 1.9 0.0 0.2 1.4 5.3 0.2 4.8 1.0 0.8 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.1 1.0 2.6 0.0 0.5 16.6 1.1 0.6 0.0 0.1 1.4 0.5 0.0 0.1 39.2 2.2 1.9 0.0 9.1 0.0 5.2 1.0 0.6 102.0 1.0 1.5 2.9 8.1 0.9 0.0 0.7 1.3 1.6 1.2 4.2 0.0 0.0 0.1 0.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.7 5.7 5.2 4.0 5.5 6.5 8.9 8.8 5.5 6.2 4.8 6.5 1.4 0.0 2.3 11.4 0.0 0.9 2.0 3.1 0.0 0.1 1.5 14.0 1.6 1.5 2.4 0.0 0.0 0.3 0.1 0.1 0.0 3.1 17.9 0.5 5.5 4.0 0.0 0.0 0.6 0.2 0.1 10.1 0.0 1.0 0.0 2.0 1.1 0.1 0.1 0.0 0.9 0.3 2.0 0.0 1.2 23.7 11.5 0.6 0.0 15.0 0.0 0.6 0.0 7.5 2.1 0.7 0.7 25.9 0.0 2.9 0.0 5.0 1.8 0.0 0.0 4.8 1.3 10.6 7.5 1.1 0.9 0.1 0.3 6.5 0.3 0.7 IRF2BP2 IRF-2BP2 ENSG00000168264 "Interferon regulatory factor 2 binding protein 2" Q7Z5L9 1 234604269-234610178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "THP-1: 277.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027815, HPA062269" Approved Enhanced Nucleoplasm NA NA 13000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA027815: AB_10609994, HPA062269: AB_2684732" "unprognostic (1.15e-3)" "unprognostic (1.02e-1)" "unprognostic (3.90e-1)" "unprognostic (2.13e-1)" "unprognostic (3.41e-3)" "unprognostic (1.69e-1)" "unprognostic (1.74e-3)" "unprognostic (1.97e-2)" "unprognostic (8.77e-2)" "unprognostic (2.19e-1)" "unprognostic (3.69e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.25e-1)" "unprognostic (2.70e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" 35.6 39.6 43.3 25.6 50.2 157.2 45.0 48.5 49.1 50.0 43.3 42.5 39.6 55.8 26.5 47.0 45.1 40.7 45.0 40.5 45.4 34.2 53.6 43.7 36.3 55.2 49.0 54.8 49.5 45.5 24.1 29.6 51.1 39.2 49.3 26.9 55.0 33.5 47.4 64.2 42.2 31.7 48.9 28.4 44.4 18.0 44.7 29.6 57.3 40.5 30.3 38.7 43.7 61.1 28.0 41.5 29.8 45.7 61.2 48.1 35.1 21.8 18.4 12.7 14.2 24.5 33.5 0.0 49.4 21.2 43.3 37.4 16.2 28.3 20.2 45.2 36.8 26.7 32.9 72.3 49.4 101.0 91.0 57.0 65.8 28.3 53.4 74.4 33.0 24.5 23.0 55.6 33.2 8.4 25.5 107.2 27.1 65.1 15.7 49.6 13.8 66.8 25.1 22.9 58.8 41.8 35.2 46.7 72.7 29.8 45.1 277.5 36.8 45.5 19.0 34.7 41.6 122.9 33.8 9.1 23.1 89.6 63.4 10.1 4.5 8.5 3.9 3.6 4.0 4.3 4.8 4.6 4.7 4.0 4.9 4.1 2.3 3.0 1.9 17.8 4.0 2.5 43.3 50.2 48.5 49.1 40.5 45.4 55.2 49.0 51.1 48.9 44.7 61.1 96.0 134.6 191.3 28.1 75.6 325.9 440.4 142.3 139.5 34.6 126.6 109.7 63.6 133.0 143.8 51.5 10.4 44.6 168.3 84.2 13.7 65.8 24.9 180.8 126.2 101.9 145.5 76.6 14.3 50.0 58.0 97.3 47.4 285.2 107.5 39.6 117.4 185.7 88.9 58.9 22.9 117.1 71.2 131.8 271.2 27.1 69.6 159.7 110.3 30.9 83.2 87.7 38.1 20.6 64.2 68.9 92.0 81.3 39.2 138.2 81.7 40.2 95.1 19.5 78.9 117.1 102.9 29.5 24.1 182.1 396.2 79.4 91.3 15.5 162.7 370.6 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISYNA1 "Ino1, INOS, IPS" ENSG00000105655 "Inositol-3-phosphate synthase 1" Q9NPH2 19 18434388-18438167 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Inositol biosynthesis, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 223.6;testis: 223.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1141.3;Sertoli cells: 315.5;Syncytiotrophoblasts: 1034.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.5;NK-cells: 14.4;T-cells: 8.9" "Cell line enriched" "Detected in many" 4 "BEWO: 492.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007931, HPA008232, CAB020720" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Cytosol "CAB020720: , HPA007931: AB_2667940, HPA008232: AB_2668018" "unprognostic (1.87e-2)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (3.16e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-2)" "unprognostic (2.49e-1)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "unprognostic (2.28e-2)" "unprognostic (2.73e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (9.23e-4)" "unprognostic (2.23e-2)" "unprognostic (9.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" 36.0 32.6 15.2 2.8 13.8 5.8 30.5 12.5 19.5 47.3 223.6 14.2 3.6 44.2 4.4 15.2 78.9 3.7 36.1 19.4 24.5 114.4 13.1 22.2 4.4 16.8 18.8 96.0 40.1 12.8 50.7 46.3 14.2 41.4 0.7 0.9 17.7 26.7 13.2 16.2 16.1 2.8 12.7 35.1 11.3 223.8 25.4 3.0 23.7 3.1 1.8 23.5 31.9 11.3 13.9 42.4 98.6 31.0 0.8 0.2 492.7 6.6 1.0 0.6 0.3 24.5 26.1 0.2 33.5 3.2 0.2 36.6 3.0 0.1 0.0 39.8 116.4 52.0 3.1 80.3 10.2 0.6 1.1 9.4 0.4 2.8 0.4 0.4 6.3 1.1 106.0 2.1 0.0 84.1 4.0 3.4 51.7 14.2 33.7 71.2 0.2 24.6 9.5 0.3 30.4 74.3 1.7 9.9 53.1 20.2 68.2 7.1 18.7 0.5 1.1 0.7 1.6 13.9 7.3 3.2 3.0 1.9 17.7 1.0 0.1 0.0 8.1 0.2 6.2 4.5 8.1 6.9 0.8 2.4 6.2 8.9 0.8 14.4 0.1 2.2 6.2 5.0 15.2 13.8 12.5 19.5 19.4 24.5 16.8 18.8 14.2 12.7 25.4 11.3 38.8 3.2 1.1 2.6 9.0 12.0 82.1 74.9 72.8 0.8 26.1 47.0 4.7 20.0 24.0 47.8 2.1 1141.3 8.4 4.1 52.8 39.4 101.3 33.4 10.9 30.5 64.8 21.5 1.0 8.2 114.0 30.2 7.1 14.8 14.0 36.9 25.7 1.1 84.9 0.0 4.3 4.0 28.5 9.0 7.8 230.1 37.3 4.1 23.2 11.2 5.4 8.6 13.4 0.0 0.3 3.4 1.8 50.4 1.8 21.6 0.7 6.1 23.6 0.7 315.5 5.6 163.6 53.7 21.0 10.6 5.7 1034.6 14.9 14.5 6.2 36.8 ITGA11 HsT18964 ENSG00000137809 "Integrin subunit alpha 11" Q9UKX5 15 68296532-68432163 "Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 26.3;endometrium 1: 53.1;smooth muscle: 25.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.8;Excitatory neurons: 13.4;Fibroblasts: 30.1;Microglial cells: 18.7;Peritubular cells: 13.5;Sertoli cells: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "fHDF/TERT166: 119.5;hTERT-RPE1: 174.5;U-138 MG: 80.6;WM-115: 45.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 7.3;spinal cord: 2.1" HPA051813 Uncertain NA NA 260000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA051813: AB_2681622" "unprognostic (4.85e-2)" "unprognostic (3.51e-1)" "unprognostic (6.20e-2)" "unprognostic (1.89e-1)" "unprognostic (1.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-2)" "unprognostic (9.29e-3)" "unprognostic (6.63e-2)" "unprognostic (5.68e-3)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (8.38e-3)" "unprognostic (2.28e-4)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" 6.5 3.4 0.2 1.1 1.5 0.2 3.2 0.7 1.1 26.3 0.4 2.1 0.8 53.1 13.5 1.5 12.0 2.4 12.7 0.2 0.3 6.5 0.7 1.7 0.5 0.2 0.2 4.6 0.8 0.4 1.8 1.5 0.1 5.2 1.3 0.4 1.2 7.4 2.1 2.7 1.6 25.0 0.1 3.2 1.6 0.9 0.1 0.2 2.0 2.4 0.1 3.9 8.2 0.5 0.0 0.2 0.4 0.9 3.7 0.1 0.1 7.9 15.1 1.6 0.5 0.1 0.2 0.1 0.6 119.5 2.1 0.2 0.0 0.0 0.4 0.0 0.2 0.5 6.8 0.0 10.8 0.2 7.0 1.5 0.0 3.1 0.3 174.5 0.0 0.1 0.2 0.3 20.9 0.1 0.1 0.4 0.7 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 5.5 0.1 0.1 18.5 0.1 0.5 5.0 80.6 0.7 2.1 0.1 0.2 0.0 0.1 13.5 0.2 45.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 1.5 0.7 1.1 0.2 0.3 0.2 0.2 0.1 0.1 0.1 0.5 2.9 0.0 0.0 0.3 0.3 0.8 0.5 0.0 0.6 3.9 1.0 7.0 13.8 0.0 0.0 1.8 0.0 0.0 0.3 0.1 1.9 0.3 0.3 0.2 0.8 1.1 0.0 0.0 13.4 0.0 0.1 30.1 1.5 0.3 0.0 0.2 2.2 0.5 0.3 0.0 0.7 0.0 0.0 0.6 1.2 0.5 6.8 0.6 0.0 18.7 0.0 0.3 0.0 0.0 0.5 0.2 0.0 13.5 0.2 0.3 0.1 0.3 0.0 1.6 19.7 2.7 5.4 0.0 0.2 0.2 0.4 0.1 0.6 0.2 0.0 0.3 ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 76.1;Skeletal myocytes: 93.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 208.3;ASC TERT1: 138.7;fHDF/TERT166: 345.3;LHCN-M2: 311.8" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 56.9" "Secreted - unknown location" NA NA 37000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" 16.9 9.2 1.8 0.7 1.8 0.1 18.0 2.6 2.3 23.8 2.5 1.5 0.5 2.0 0.5 9.7 4.9 38.3 18.3 1.9 3.6 2.7 7.7 25.4 1.3 3.9 2.3 5.3 7.9 5.6 10.3 33.4 4.3 4.0 2.5 0.1 11.7 4.4 4.5 13.2 0.5 4.1 3.5 4.0 7.2 2.5 2.2 0.9 8.4 14.9 4.3 17.8 10.0 6.5 4.2 0.3 0.0 0.0 208.3 138.7 0.0 65.8 67.7 29.3 18.7 0.0 2.4 0.0 0.3 345.3 13.9 70.9 0.0 24.1 46.0 0.0 0.0 21.3 0.6 0.0 21.7 0.0 0.0 59.3 1.5 16.8 46.6 55.3 76.8 0.0 1.5 0.7 311.8 0.0 0.0 0.0 0.0 0.0 24.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 8.8 24.0 33.2 27.3 0.1 8.3 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 2.6 2.3 1.9 3.6 3.9 2.3 4.3 3.5 2.2 6.5 1.9 3.2 0.5 5.5 0.1 4.0 0.1 1.3 0.6 1.8 4.2 19.0 0.5 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.5 4.5 0.5 7.7 1.2 0.0 0.0 3.6 0.2 0.8 76.1 5.6 1.1 0.0 0.0 8.6 0.5 0.7 5.0 6.7 0.0 0.0 0.0 4.7 2.1 0.0 0.8 5.4 13.1 0.0 0.5 0.0 2.0 5.0 1.1 0.0 8.2 0.6 0.2 0.0 0.1 0.0 0.7 0.0 93.0 4.8 11.6 8.4 0.7 2.4 0.8 0.4 1.2 0.0 0.2 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 322.9" "Cell type enhanced" "Detected in many" "Adipocytes: 390.0;Endothelial cells: 368.4;Fibroblasts: 302.1;granulocytes: 194.6;Leydig cells: 335.5;Muller glia cells: 188.9;T-cells: 239.2" "Cancer enhanced" "Detected in all" "glioma: 51.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 172.6;eosinophil: 88.5;gdT-cell: 107.1;MAIT T-cell: 79.3;memory CD4 T-cell: 204.7;memory CD8 T-cell: 170.5;naive CD4 T-cell: 216.7;naive CD8 T-cell: 101.6;NK-cell: 130.3;T-reg: 168.1" "Group enriched" "Detected in all" 7 "granulocytes: 172.6;NK-cells: 130.3;T-cells: 216.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 1749.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (1.05e-2)" "unprognostic (5.22e-3)" "unprognostic (2.77e-3)" "unprognostic (5.65e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-3)" "prognostic favorable (3.66e-6)" "unprognostic (1.57e-1)" "unprognostic (4.94e-2)" "unprognostic (9.85e-2)" "unprognostic (1.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.31e-1)" "unprognostic (2.18e-1)" "unprognostic (4.30e-1)" 80.2 10.8 103.4 26.8 95.2 45.8 74.5 99.4 172.0 55.3 75.5 30.5 15.1 44.4 18.8 40.1 42.8 28.8 115.3 92.1 105.4 20.6 6.3 52.2 87.2 101.5 102.2 181.4 10.0 14.9 21.0 29.7 102.0 22.8 32.2 11.9 74.9 22.4 41.2 25.0 22.1 56.6 95.2 24.5 24.2 15.9 109.8 322.9 83.1 75.2 46.9 42.3 26.0 95.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 216.6 2.5 0.0 4.4 0.0 69.9 0.0 0.0 0.0 113.1 124.2 19.5 0.0 0.0 0.0 0.1 0.0 333.3 80.2 0.0 0.0 0.0 1749.0 77.6 25.0 0.0 0.0 0.7 0.1 0.3 64.6 0.0 0.2 19.0 0.0 0.9 0.0 17.6 2.2 2.5 3.0 0.0 1.8 0.4 1.1 208.1 0.0 0.0 0.2 0.0 8.7 172.6 0.8 88.5 107.1 1.3 79.3 23.4 204.7 170.5 0.8 23.5 216.7 101.6 3.9 130.3 1.1 6.1 168.1 115.3 103.4 95.2 99.4 172.0 92.1 105.4 101.5 102.2 102.0 95.2 109.8 95.8 390.0 3.2 14.8 1.0 28.0 67.4 13.2 2.1 50.1 3.1 21.1 81.9 29.3 2.8 4.4 1.8 0.0 0.4 64.8 2.1 5.9 0.4 3.1 0.4 2.6 368.4 2.4 42.7 3.5 50.9 0.2 302.1 29.6 0.6 194.6 1.4 135.0 1.0 1.3 1.7 2.3 85.6 0.0 9.5 39.5 7.1 335.5 8.6 62.2 114.3 3.2 188.9 65.9 18.1 60.2 1.0 1.4 117.8 81.8 12.3 0.2 1.4 0.7 12.1 0.0 31.8 22.5 0.5 2.6 24.3 47.0 0.3 239.2 2.0 2.9 2.5 JAM3 "JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 342.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;RH-30: 122.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" NA NA 44000 "Cluster 43: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" 23.6 18.7 53.4 10.1 86.3 1.3 19.2 68.7 73.4 33.4 52.9 54.6 6.6 40.8 17.5 21.5 28.7 24.5 31.0 56.5 61.3 11.4 3.2 29.6 7.8 73.5 76.8 48.7 5.1 17.7 33.3 102.7 71.0 32.5 12.9 47.3 13.3 44.5 7.0 13.0 22.5 42.8 59.7 13.5 22.4 35.7 73.3 17.6 15.8 14.6 7.5 41.7 23.4 115.2 0.0 1.0 87.9 42.5 85.3 62.7 75.4 37.0 49.1 15.1 14.8 0.3 0.6 0.0 38.7 53.3 56.2 0.5 70.0 0.7 28.2 0.2 29.6 0.3 0.0 6.9 24.9 0.4 36.2 43.2 0.0 10.7 9.6 35.8 99.5 40.8 0.3 0.2 64.5 1.0 27.5 0.2 18.9 0.6 2.9 0.5 122.8 0.0 0.9 0.2 57.5 32.2 0.0 0.2 1.0 35.3 0.2 0.2 0.6 25.1 18.4 40.3 24.7 0.1 0.1 0.4 27.6 1.2 48.0 0.0 0.0 0.1 1.3 0.0 1.6 5.3 1.6 0.9 0.0 3.1 2.3 1.7 0.5 0.0 0.0 0.0 0.0 1.8 53.4 86.3 68.7 73.4 56.5 61.3 73.5 76.8 71.0 59.7 73.3 115.2 22.2 0.0 6.0 12.7 10.9 5.1 5.6 0.9 0.0 21.7 0.3 9.3 15.7 0.0 0.7 5.5 8.4 6.0 1.2 0.1 1.9 0.4 2.1 0.8 23.3 35.5 0.0 0.4 84.3 0.2 71.2 29.6 1.5 0.5 1.3 11.7 12.5 0.0 8.6 8.4 44.2 0.0 12.2 0.6 4.2 4.9 42.9 10.9 17.8 24.4 0.2 20.2 1.0 76.4 342.8 0.3 0.0 64.3 0.9 2.2 0.0 0.2 1.5 75.6 26.3 19.0 24.3 15.5 19.2 0.2 3.8 6.2 3.5 9.7 0.0 1.0 JAZF1 "DKFZp761K2222, TIP27, ZNF802" ENSG00000153814 "JAZF zinc finger 1" Q86VZ6 7 27830573-28180795 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid metabolism, Transcription, Transcription regulation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 83.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 160.1;Excitatory neurons: 316.6;Inhibitory neurons: 306.3;Microglial cells: 168.6;Oligodendrocyte precursor cells: 241.3;Oligodendrocytes: 262.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 25.6" "Group enriched" "Detected in all" 4 "dendritic cells: 13.7;granulocytes: 25.6" "Cell line enhanced" "Detected in many" "Karpas-707: 53.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019271, HPA066967" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "CAB019271: , HPA066967: AB_2685758" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.18e-2)" "unprognostic (7.48e-2)" "unprognostic (9.08e-2)" "unprognostic (1.14e-1)" "unprognostic (2.74e-1)" "unprognostic (8.88e-2)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (8.27e-3)" "unprognostic (2.32e-2)" "unprognostic (1.26e-2)" "unprognostic (7.18e-3)" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-2)" 15.4 83.8 11.1 10.9 12.4 24.4 11.7 11.5 16.5 62.4 12.4 32.8 3.4 41.8 21.3 10.1 16.4 12.4 22.4 13.2 15.3 5.1 15.7 10.1 14.6 7.3 8.3 13.9 6.6 6.3 13.4 16.1 9.1 29.5 8.3 7.8 4.6 35.2 6.9 7.1 8.3 38.6 8.1 14.6 8.3 18.8 17.4 11.5 14.9 6.9 15.9 19.2 27.3 10.0 1.4 0.8 4.8 1.0 35.6 42.9 0.0 11.1 28.6 18.4 22.8 0.1 7.6 33.7 22.6 23.5 12.5 0.7 6.3 8.5 15.0 5.1 10.2 12.2 7.7 0.0 24.2 4.8 3.1 19.4 10.2 13.8 8.9 14.1 11.8 2.2 0.3 53.2 10.3 1.4 1.3 17.5 10.0 0.2 7.7 3.6 2.2 10.1 6.7 0.3 3.0 4.7 9.2 0.3 12.0 14.0 3.5 6.1 11.7 29.0 11.0 8.0 12.9 9.2 2.9 12.5 9.2 12.5 16.2 25.6 3.9 6.9 4.8 3.3 1.3 2.8 1.3 3.2 3.7 3.7 0.5 3.0 1.5 4.1 3.5 13.7 3.2 3.1 11.1 12.4 11.5 16.5 13.2 15.3 7.3 8.3 9.1 8.1 17.4 10.0 10.2 3.2 7.0 57.8 33.4 14.7 3.0 3.8 3.4 6.7 3.5 4.8 25.3 10.0 3.0 1.8 6.2 0.5 37.9 1.3 7.9 14.8 122.1 28.3 160.1 14.5 5.4 115.6 316.6 2.3 1.4 24.6 9.2 18.6 24.1 12.6 3.6 5.5 9.4 16.8 306.3 0.6 2.0 25.7 45.6 89.8 55.0 28.0 23.2 168.6 35.5 4.4 40.2 241.3 262.5 5.3 0.4 34.6 8.7 2.7 0.0 2.4 12.7 4.7 13.1 9.9 15.3 8.7 16.5 3.4 11.2 1.4 25.3 1.6 0.3 1.5 JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 295.6" "Low region specificity" "Detected in all" "CAB003801, CAB007780, HPA031174, HPA059474" Enhanced Enhanced Nucleoplasm Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB003801: AB_365485, CAB007780: AB_562268, HPA031174: , HPA059474: AB_2684030" "unprognostic (2.06e-2)" "unprognostic (1.76e-2)" "unprognostic (1.34e-1)" "unprognostic (7.85e-2)" "unprognostic (1.60e-1)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (5.21e-2)" "unprognostic (1.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.14e-1)" "unprognostic (2.82e-1)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.83e-1)" "unprognostic (2.37e-1)" "unprognostic (2.81e-3)" 331.1 92.7 34.4 36.3 37.0 129.1 308.2 41.6 38.1 172.0 28.0 154.7 34.7 116.4 15.8 100.2 314.1 89.6 158.4 39.1 37.2 94.0 205.2 202.8 52.1 32.7 30.7 197.0 192.2 59.8 75.0 40.1 30.5 153.4 55.0 29.7 154.5 71.7 114.3 286.6 79.1 113.3 34.3 62.0 239.5 20.2 33.8 71.5 189.5 158.8 5.4 156.4 164.5 36.9 49.8 2.8 22.4 2.6 35.3 40.0 0.2 69.4 27.0 57.1 34.3 10.1 3.5 1.7 23.8 57.4 133.6 12.9 2.0 27.7 40.6 29.8 128.9 0.5 1.9 16.9 29.4 5.3 10.2 42.0 74.0 78.1 34.0 27.7 47.2 2.4 15.6 29.6 24.9 8.0 2.5 32.5 13.5 34.6 32.2 1.1 295.6 7.0 60.7 5.8 43.7 12.8 49.9 62.3 26.4 24.5 17.2 3.0 61.6 127.5 37.3 35.3 96.8 37.9 9.8 4.4 133.9 8.4 35.2 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.0 0.1 0.2 0.6 0.0 0.0 0.0 0.0 34.4 37.0 41.6 38.1 39.1 37.2 32.7 30.7 30.5 34.3 33.8 36.9 2721.4 538.5 543.8 187.7 1018.8 1235.5 2850.5 772.6 2825.1 103.4 1647.1 2067.3 1487.5 1315.4 449.3 104.8 262.7 675.8 651.1 1653.6 50.9 987.0 49.3 1337.1 2845.2 1443.8 1497.4 174.3 12.2 516.4 93.9 2730.7 2663.1 1822.2 541.9 333.4 737.2 158.6 650.5 87.5 4.9 1909.1 836.2 584.9 632.0 48.2 1227.4 1034.9 757.7 65.6 140.1 1234.2 8.2 17.6 10.0 562.8 1529.6 258.8 1540.3 1489.1 1654.1 48.6 216.3 453.5 1538.3 1892.9 2392.5 17.4 20.9 2146.3 964.4 415.6 1065.5 846.5 1199.5 545.7 KANK4 "ANKRD38, KIAA0172" ENSG00000132854 "KN motif and ankyrin repeat domains 4" Q5T7N3 1 62236165-62319434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6;pancreas: 15.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 31.8;Exocrine glandular cells: 8.0;Extravillous trophoblasts: 19.0;Oligodendrocytes: 34.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 31.8;Hep G2: 13.4;SCLC-21H: 6.2;SuSa: 27.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014030 Uncertain Uncertain Microtubules,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol Microtubules "HPA014030: AB_2128155" "unprognostic (1.66e-2)" "unprognostic (1.90e-3)" "unprognostic (2.65e-2)" "unprognostic (1.11e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-2)" "unprognostic (6.31e-2)" "unprognostic (1.66e-2)" "unprognostic (3.58e-2)" "unprognostic (1.54e-1)" "unprognostic (3.85e-3)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (9.06e-2)" "unprognostic (1.97e-1)" "unprognostic (3.31e-2)" "unprognostic (7.74e-6)" 10.7 0.5 1.0 0.5 5.8 0.0 2.6 10.1 3.2 0.3 0.1 1.0 0.3 0.2 0.7 0.2 0.3 0.5 0.3 0.8 4.6 1.4 3.0 2.5 0.0 19.2 13.8 0.3 15.2 5.6 0.1 10.8 22.6 1.5 1.0 1.0 8.4 0.6 0.2 0.5 0.3 0.2 5.3 0.8 2.0 0.9 7.6 0.8 0.3 0.8 0.0 0.2 0.5 8.9 0.0 0.0 1.1 0.0 0.0 0.0 31.8 0.1 0.0 0.1 0.0 4.8 0.0 0.0 0.1 1.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.4 13.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.2 0.0 1.0 0.6 0.0 27.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 5.8 10.1 3.2 0.8 4.6 19.2 13.8 22.6 5.3 7.6 8.9 0.1 0.0 0.0 1.3 0.0 0.0 2.4 0.4 0.6 0.3 0.5 7.0 0.9 0.0 0.0 0.0 0.0 31.8 0.0 0.5 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.0 2.3 8.0 19.0 0.9 0.0 0.1 0.0 0.1 0.4 1.5 2.3 0.0 2.3 1.4 0.0 0.0 0.0 0.3 0.0 0.4 1.8 1.0 0.0 0.1 0.0 0.5 34.3 0.4 0.2 3.8 0.0 0.0 0.0 0.8 0.0 0.5 0.0 1.2 4.2 0.0 1.0 0.2 0.0 5.5 0.1 0.0 1.0 0.1 KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307551 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 144.3;Excitatory neurons: 80.6;Oligodendrocytes: 78.5;Spermatocytes: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 63.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046205 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA046205: AB_10965325" "unprognostic (3.34e-1)" "unprognostic (6.44e-3)" "unprognostic (2.08e-2)" "unprognostic (6.91e-2)" "unprognostic (2.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.57e-2)" "unprognostic (2.84e-2)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (4.54e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-3)" "unprognostic (7.41e-2)" "unprognostic (6.42e-2)" "unprognostic (5.12e-2)" "unprognostic (1.83e-3)" 8.7 3.8 7.0 5.0 8.8 6.5 4.7 7.5 8.9 9.7 0.0 8.7 1.4 9.3 2.7 5.8 4.8 3.8 17.9 8.0 8.1 4.0 3.9 4.9 6.5 7.2 6.4 4.2 1.9 2.2 2.9 3.0 7.0 4.5 4.1 7.9 2.2 5.9 5.1 2.6 2.8 15.0 7.5 3.3 2.8 20.8 8.4 9.2 3.0 6.6 7.1 5.0 5.2 11.8 11.7 9.6 16.5 8.8 12.3 26.0 0.4 47.5 15.2 24.9 19.4 1.9 11.6 18.8 5.5 63.7 31.3 3.2 11.8 12.2 37.5 16.3 4.4 13.4 11.2 4.4 6.5 6.7 8.7 10.1 6.0 28.0 6.8 23.3 26.4 10.2 7.3 8.1 30.8 2.4 15.2 6.1 7.1 0.2 6.1 16.8 19.4 1.9 8.8 0.8 6.8 14.3 12.6 2.6 9.0 13.6 4.1 4.1 24.2 21.8 32.7 12.1 19.3 4.2 8.2 25.8 8.7 6.5 32.1 1.5 0.7 2.9 4.4 0.4 2.1 1.9 3.4 4.4 1.9 4.5 0.8 1.8 0.2 7.7 0.9 5.5 5.8 1.2 7.0 8.8 7.5 8.9 8.0 8.1 7.2 6.4 7.0 7.5 8.4 11.8 12.9 9.6 1.8 30.3 7.2 5.9 3.9 4.7 6.2 10.2 4.0 5.6 41.4 2.8 2.3 5.5 27.1 0.4 6.6 0.3 3.9 6.5 144.3 10.3 26.5 9.3 10.2 16.4 80.6 1.5 0.8 12.3 1.5 3.6 10.1 10.3 7.9 10.6 2.9 21.9 34.5 1.0 0.0 2.8 8.9 50.7 9.0 5.9 17.8 21.5 21.9 9.6 13.4 29.1 78.5 5.7 0.0 5.3 6.4 1.9 0.3 8.4 14.7 18.7 6.6 11.9 13.7 59.0 24.6 5.2 5.7 0.3 9.8 19.2 0.7 1.7 KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.0;Gastric mucus-secreting cells: 44.4;Intestinal goblet cells: 53.5;Proximal enterocytes: 78.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 30.8;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011800 Uncertain "Secreted to extracellular matrix" NA NA 65000 "Cluster 64: Macrophages - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" 2.9 0.6 0.3 0.6 0.2 0.3 2.8 0.3 0.4 7.1 0.1 1.9 2.8 2.0 1.3 0.6 2.1 0.6 8.1 0.5 0.2 2.0 0.5 1.2 0.7 0.4 0.3 0.5 0.9 0.8 3.6 0.8 0.4 5.2 1.6 0.4 6.9 2.2 4.1 1.7 3.2 1.5 0.2 18.0 6.6 1.9 0.4 1.0 2.5 3.1 0.3 3.6 2.9 0.2 3.3 1.6 1.8 30.8 1.8 7.4 2.0 5.2 5.6 1.0 1.0 6.2 2.0 0.2 2.8 4.6 0.5 0.7 1.9 0.1 0.3 3.1 0.8 0.4 6.5 6.7 0.5 0.4 2.3 1.1 0.4 0.1 0.9 0.4 0.0 0.9 0.7 3.2 0.9 5.3 0.1 1.9 0.5 7.2 11.7 12.4 9.1 0.4 0.6 1.6 0.3 1.2 0.5 0.8 1.7 0.7 36.7 0.5 0.1 0.7 2.1 0.5 1.2 0.9 2.6 2.5 1.3 3.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.4 0.5 0.2 0.4 0.3 0.4 0.2 0.4 0.2 8.3 0.0 1.5 0.7 0.3 2.0 0.9 1.6 0.6 1.5 2.5 3.0 3.4 1.5 1.6 0.0 2.1 0.3 0.3 23.0 1.9 0.5 0.1 4.1 1.3 5.1 2.4 2.7 0.1 2.1 0.6 16.9 44.4 7.2 0.0 0.2 3.6 0.3 0.8 0.0 0.1 53.5 4.1 4.8 1.9 0.1 9.9 0.9 1.8 0.0 0.0 0.8 0.0 0.0 0.1 1.5 12.8 0.4 0.2 5.0 78.1 0.4 0.7 2.2 0.0 10.4 6.1 3.9 1.4 0.7 2.8 0.5 0.6 0.2 8.1 0.4 KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273175-120750337 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 47.3" "Group enriched" "Detected in some" 11 "Excitatory neurons: 690.0;Inhibitory neurons: 1068.2;Oligodendrocyte precursor cells: 1952.8" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.8;HSkMC: 2.9;NTERA-2: 2.4;RT4: 2.7;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA029068: AB_10601436" "unprognostic (4.22e-1)" "unprognostic (2.79e-4)" "unprognostic (3.79e-2)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-3)" "unprognostic (9.07e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.77e-3)" "unprognostic (1.51e-1)" "unprognostic (4.51e-4)" "unprognostic (4.07e-5)" "unprognostic (2.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.83e-3)" 1.7 0.5 8.1 0.5 10.5 0.0 1.0 47.3 8.6 1.1 0.0 0.3 0.3 3.2 0.1 0.1 1.2 4.2 0.2 5.5 10.1 0.0 0.1 0.2 0.1 29.3 15.4 3.3 0.2 0.7 1.9 0.4 26.8 0.2 0.2 1.0 0.3 0.9 0.2 0.1 0.1 2.0 4.9 0.0 0.2 1.7 19.2 0.3 0.4 2.8 0.0 1.1 0.5 2.5 0.0 0.0 0.2 0.0 1.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 2.7 13.2 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 10.5 47.3 8.6 5.5 10.1 29.3 15.4 26.8 4.9 19.2 2.5 0.6 0.0 0.0 108.7 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 1.2 4.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 2.7 1.0 1.9 0.3 0.0 2.7 690.0 0.2 0.0 6.0 0.0 0.8 0.0 6.6 0.7 0.0 0.0 0.0 1068.2 0.0 2.0 0.0 0.0 1.7 3.7 0.1 0.0 40.3 0.0 0.0 0.0 1952.8 9.7 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.3 0.5 0.0 10.9 3.0 5.0 3.4 0.0 0.1 0.0 0.0 4.3 0.0 0.1 KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Cell type enhanced" "Detected in some" "Astrocytes: 57.8;Horizontal cells: 50.5;Inhibitory neurons: 221.4;Microglial cells: 167.7;Oligodendrocyte precursor cells: 196.1" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "RPTEC TERT1: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" 0.5 4.2 23.5 0.5 26.5 0.0 1.0 19.4 28.3 2.7 15.1 0.7 0.2 1.6 21.6 0.3 1.7 1.8 0.4 21.8 32.6 3.8 0.1 1.0 0.5 24.3 26.6 0.3 1.4 1.3 1.0 1.2 24.7 1.5 0.5 5.8 0.4 5.6 0.1 0.4 0.3 1.1 28.7 1.5 0.4 2.7 32.7 0.1 0.7 0.2 0.4 0.5 0.6 19.6 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 26.5 19.4 28.3 21.8 32.6 24.3 26.6 24.7 28.7 32.7 19.6 0.0 0.0 0.0 57.8 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 2.0 1.2 0.0 0.0 18.6 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 50.5 221.4 0.0 0.0 0.0 0.6 0.7 5.0 0.1 0.0 167.7 0.0 0.2 0.0 196.1 2.8 0.0 0.0 11.7 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 KCTD12 "C13orf2, KIAA1778, PFET1" ENSG00000178695 "Potassium channel tetramerization domain containing 12" Q96CX2 13 76880175-76886405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 281.2;Endothelial cells: 192.2;Enteroendocrine cells: 386.7;Hofbauer cells: 218.9;Kupffer cells: 395.9;Macrophages: 221.3;monocytes: 206.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 3.9;myeloid DC: 3.7" "Group enriched" "Detected in many" 17 "dendritic cells: 3.7;granulocytes: 1.0;monocytes: 3.9" "Cell line enhanced" "Detected in many" "ASC diff: 111.4;HUVEC TERT2: 229.0;TIME: 186.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056987, HPA077376" Supported Approved Mitochondria NA NA 21000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA056987: , HPA077376: " "unprognostic (6.42e-2)" "unprognostic (2.67e-1)" "unprognostic (5.13e-1)" "unprognostic (1.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.98e-2)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (1.90e-1)" "unprognostic (9.83e-3)" "unprognostic (1.23e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.11e-2)" "unprognostic (1.65e-2)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" 76.1 27.8 21.4 55.7 20.1 12.0 52.4 27.0 20.8 44.5 12.4 39.5 22.5 51.3 17.8 38.3 75.0 55.0 22.6 26.9 27.8 31.0 13.9 58.0 39.4 36.2 33.5 47.1 12.5 25.2 6.4 83.9 31.4 14.7 42.5 3.4 20.0 18.5 16.6 22.9 28.1 65.3 37.0 64.8 28.0 26.9 31.4 18.3 16.4 37.1 33.4 39.2 17.4 34.4 1.7 1.5 15.3 0.0 111.4 52.5 4.3 6.9 1.5 4.2 5.5 0.5 0.3 0.0 3.8 18.8 4.9 53.9 6.6 66.4 3.5 1.5 35.1 0.2 38.3 0.0 4.7 18.6 0.1 21.4 21.5 2.7 48.9 8.5 229.0 13.2 0.3 0.2 53.9 1.4 8.5 0.3 7.8 16.6 7.7 0.4 7.4 19.6 17.7 0.2 4.3 7.9 17.3 0.5 2.2 18.5 1.0 12.1 186.0 2.7 4.9 0.4 14.0 2.7 0.5 0.0 42.5 4.0 16.1 0.0 3.9 0.7 0.0 2.5 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.0 0.0 1.5 1.9 0.0 0.9 21.4 20.1 27.0 20.8 26.9 27.8 36.2 33.5 31.4 37.0 31.4 34.4 281.2 25.6 8.4 2.9 7.5 40.0 2.7 11.9 28.5 4.4 11.2 27.3 21.8 4.3 16.3 97.5 14.6 3.0 30.4 19.7 17.6 6.5 3.6 4.9 44.6 192.2 386.7 6.1 4.8 0.6 90.6 80.0 12.2 3.3 7.0 53.1 61.1 2.5 218.9 0.0 11.5 71.5 12.2 395.9 75.4 11.8 157.2 221.3 51.6 45.9 206.7 4.8 7.2 0.5 0.9 0.5 15.7 44.8 7.6 4.5 0.7 7.5 72.8 1.5 26.3 153.2 32.2 1.9 7.0 16.9 34.4 4.2 5.5 24.0 46.6 1.9 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "intestine: 121.2;kidney: 104.4;liver: 180.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 428.5;Proximal enterocytes: 1858.7;Proximal tubular cells: 1019.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 32.8;Hep G2: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 2.2 4.6 4.2 3.0 4.3 1.7 2.0 7.1 5.9 2.6 1.2 4.2 112.4 3.8 0.6 2.4 4.3 1.3 1.4 4.8 3.9 104.4 180.5 1.6 1.9 5.4 4.0 3.6 9.4 2.6 1.4 0.5 5.5 1.6 1.2 1.5 4.4 1.4 3.8 2.4 121.2 1.9 3.6 2.0 2.9 3.2 3.8 0.7 1.1 2.0 1.2 1.8 2.3 4.7 25.0 18.5 2.8 11.0 2.0 0.5 2.5 1.7 1.1 2.3 1.4 9.0 5.3 3.7 5.8 0.1 2.6 10.7 9.4 3.1 0.8 8.8 17.2 32.8 5.2 48.0 1.1 4.6 3.7 0.1 1.3 2.7 0.2 1.2 2.1 5.1 5.9 6.1 0.2 16.0 5.4 3.6 4.0 22.3 7.2 18.9 1.4 20.9 2.7 3.0 10.2 15.8 3.6 6.2 6.9 1.0 2.7 2.0 1.9 0.7 3.6 1.6 6.5 7.5 14.4 6.3 3.0 10.7 1.8 0.0 5.4 0.3 4.1 3.1 5.5 3.8 6.6 6.0 4.9 3.6 4.7 5.8 0.5 4.9 1.4 6.1 4.7 4.9 4.2 4.3 7.1 5.9 4.8 3.9 5.4 4.0 5.5 3.6 3.8 4.7 6.5 3.2 3.7 1.6 6.8 3.6 2.6 0.8 6.8 3.6 4.7 5.8 1.8 20.0 1.0 40.5 2.1 4.1 1.3 7.4 129.1 3.2 1.2 0.1 0.6 5.5 6.0 15.6 3.4 3.0 3.6 2.4 3.6 0.3 4.5 2.9 9.7 428.5 8.3 6.7 2.7 89.6 4.1 11.9 2.0 6.2 1.8 10.8 8.8 0.0 1.9 9.8 4.1 2.5 2.3 2.1 95.7 1.5 8.0 0.7 1858.7 1019.7 0.0 5.4 0.0 5.0 5.0 1.1 5.8 4.6 6.8 9.4 6.8 0.8 82.6 2.2 KIAA1841 ENSG00000162929 KIAA1841 Q6NSI8 2 61065871-61138034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 11.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 91.2;Inhibitory neurons: 78.5;Oligodendrocytes: 63.8;Respiratory ciliated cells: 58.0;Rod photoreceptor cells: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051240 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli" "HPA051240: AB_2681401" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.18e-2)" "unprognostic (5.71e-8)" "unprognostic (1.13e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (6.09e-2)" "unprognostic (8.92e-2)" "unprognostic (7.85e-6)" "unprognostic (8.54e-2)" "unprognostic (1.04e-2)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" 2.4 1.6 3.2 1.8 3.7 1.1 1.8 4.1 6.2 4.2 1.2 3.2 2.6 1.8 2.2 1.6 3.4 1.3 2.5 3.4 3.3 1.2 1.0 3.6 1.5 5.2 3.2 1.0 1.6 1.3 3.3 1.6 5.7 4.2 3.7 11.2 1.4 1.3 1.8 3.9 2.8 2.4 2.2 1.4 2.5 3.7 5.2 2.5 1.8 2.2 1.6 1.5 1.8 6.1 5.1 10.9 12.5 5.3 6.5 7.7 4.3 10.1 2.2 4.8 4.4 3.4 3.2 2.1 2.6 7.5 9.8 6.3 8.2 3.3 6.7 10.0 3.0 2.2 6.9 8.8 3.5 2.5 2.0 3.7 4.9 8.8 3.1 5.3 7.1 3.0 2.1 1.7 13.5 0.4 2.1 1.7 3.9 5.9 2.5 6.7 10.5 0.5 5.4 10.6 7.5 4.7 11.8 2.6 3.4 9.1 1.8 2.7 9.4 7.8 3.1 6.5 6.8 1.0 3.1 3.0 5.6 1.8 5.5 0.4 0.5 1.8 0.4 0.7 0.4 0.5 0.4 0.2 0.5 0.1 0.0 0.3 1.3 0.5 1.0 0.3 1.5 0.2 3.2 3.7 4.1 6.2 3.4 3.3 5.2 3.2 5.7 2.2 5.2 6.1 12.9 6.4 5.8 26.1 1.5 2.5 3.2 4.4 1.8 14.5 3.5 2.8 7.0 2.8 11.6 3.7 56.3 1.1 4.5 7.5 0.0 3.8 4.0 22.4 8.3 8.0 7.7 5.5 91.2 6.2 2.7 8.0 14.8 4.5 1.3 18.6 7.1 0.9 5.8 8.4 78.5 5.3 4.1 5.9 5.3 2.6 3.7 5.2 3.6 22.5 9.1 5.1 7.2 19.1 63.8 9.2 8.4 1.9 2.0 4.0 4.7 0.8 58.0 45.4 0.0 4.4 7.5 10.5 20.7 4.8 3.3 0.4 4.0 0.9 4.7 2.7 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KLHL13 "BKLHD2, FLJ10262, KIAA1309" ENSG00000003096 "Kelch like family member 13" Q9P2N7 X 117897813-118117340 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Inhibitory neurons: 29.3;Microglial cells: 30.9;Oligodendrocyte precursor cells: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 7.3;plasmacytoid DC: 4.1" "Group enriched" "Detected in many" 5 "dendritic cells: 4.1;granulocytes: 7.3" "Cell line enhanced" "Detected in many" "HAP1: 33.8;HeLa: 57.3;RH-30: 37.2;RPTEC TERT1: 106.0;SH-SY5Y: 94.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046039, HPA059901" Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA046039: AB_2679514, HPA059901: AB_2684155" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (1.03e-1)" "unprognostic (6.09e-2)" "unprognostic (1.07e-2)" "unprognostic (9.54e-2)" "unprognostic (7.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.54e-1)" "unprognostic (6.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.09e-3)" "unprognostic (1.24e-2)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (2.31e-1)" 2.7 7.3 4.6 2.6 11.1 0.4 24.6 2.7 4.8 20.5 5.5 5.4 3.1 31.4 7.3 5.9 10.7 5.6 7.8 3.2 5.9 16.0 4.7 1.4 0.6 5.9 10.3 7.4 4.6 3.4 2.2 0.8 6.4 6.2 3.9 4.2 2.2 12.3 3.6 1.1 4.8 29.3 4.0 1.6 3.2 3.6 5.9 5.0 0.8 5.6 1.2 7.5 5.0 3.8 1.1 0.4 6.9 14.5 0.1 0.0 0.2 0.5 0.0 0.4 0.0 9.1 0.1 0.0 16.5 0.0 0.7 16.9 33.8 5.6 0.0 0.0 12.9 0.4 57.3 0.1 0.8 1.1 2.2 1.8 2.3 0.2 0.7 6.9 25.8 0.0 0.0 0.0 0.0 1.4 5.9 1.6 13.4 0.0 9.6 0.0 37.2 0.1 106.0 4.0 0.0 94.3 0.5 1.2 0.9 2.7 20.9 0.2 0.7 2.4 2.9 2.0 8.6 0.4 0.0 0.2 10.2 0.0 4.1 2.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.6 0.6 0.0 1.1 0.0 4.1 0.2 0.3 4.6 11.1 2.7 4.8 3.2 5.9 5.9 10.3 6.4 4.0 5.9 3.8 0.7 0.0 0.0 13.7 0.0 0.8 6.8 5.4 12.0 6.2 2.4 19.9 10.5 0.0 4.8 1.8 0.0 0.2 0.1 1.2 29.4 1.1 0.3 8.0 22.7 1.9 1.2 1.3 8.0 3.4 0.1 8.7 0.0 1.3 0.0 10.0 8.6 1.3 0.6 0.0 29.3 2.1 0.0 0.0 1.2 0.9 6.2 1.0 1.8 30.9 0.2 7.2 0.0 102.5 12.3 0.7 3.4 1.9 0.1 2.7 2.9 12.7 22.3 1.2 6.6 18.1 5.3 1.8 10.6 4.8 0.4 0.0 0.6 6.4 4.1 3.6 KLHL23 "FLJ37812, MGC22679, MGC2610" ENSG00000213160 "Kelch like family member 23" Q8NBE8 2 169694488-169776989 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 132.5;Cone photoreceptor cells: 89.6;Sertoli cells: 170.9;Smooth muscle cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047593 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Actin filaments" "HPA047593: " "unprognostic (4.77e-2)" "unprognostic (2.65e-2)" "unprognostic (7.48e-2)" "unprognostic (4.12e-3)" "unprognostic (1.66e-2)" "unprognostic (2.13e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.19e-2)" "unprognostic (3.64e-3)" "unprognostic (1.05e-2)" "unprognostic (4.09e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (2.43e-5)" "unprognostic (2.61e-1)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (4.87e-3)" 6.9 2.1 8.1 6.1 9.6 1.7 6.2 13.2 9.9 9.6 0.2 20.8 11.1 25.6 4.0 12.0 8.9 6.7 8.0 9.8 7.2 6.6 5.9 5.9 3.1 3.7 5.8 17.9 7.2 6.4 3.3 12.8 4.6 13.6 13.9 13.6 8.0 12.5 12.0 1.6 11.8 25.0 4.0 2.8 5.1 10.9 7.6 11.1 8.1 16.3 2.9 8.7 3.9 6.3 17.0 8.6 64.5 18.3 3.6 1.3 43.7 8.0 6.1 14.4 15.8 18.0 14.4 10.6 6.7 0.8 20.9 2.6 67.7 5.8 21.9 37.7 33.2 31.3 16.9 29.9 5.4 44.2 4.7 2.5 4.7 6.0 10.2 9.3 11.2 38.3 43.5 1.4 4.8 8.2 65.0 17.9 52.7 9.0 6.7 20.7 55.1 1.1 13.1 49.9 83.4 57.1 12.7 1.2 7.8 20.3 10.6 14.2 4.2 5.8 18.6 5.7 13.6 4.9 4.9 47.3 4.5 13.0 9.0 0.0 0.0 0.0 0.7 0.0 0.9 0.3 0.6 0.5 0.1 0.3 1.0 1.0 0.0 3.4 0.0 0.9 0.8 0.3 8.1 9.6 13.2 9.9 9.8 7.2 3.7 5.8 4.6 4.0 7.6 6.3 13.7 3.2 8.7 0.0 1.1 1.5 6.9 2.8 7.4 132.5 15.0 17.1 52.9 14.3 6.7 0.0 89.6 5.6 3.8 14.6 3.9 15.6 4.6 2.4 12.8 12.6 31.8 9.7 0.0 30.5 9.6 11.2 4.1 5.5 0.0 27.5 7.5 11.8 0.9 40.4 0.0 21.2 28.5 0.8 1.9 3.7 2.5 1.3 0.0 0.0 0.2 14.6 5.2 0.0 0.0 16.1 13.6 8.6 0.4 17.2 9.7 16.9 4.9 34.8 170.9 11.4 102.6 3.4 20.9 4.7 1.0 1.2 5.5 13.8 20.9 4.1 KLHL33 ENSG00000185271 "Kelch like family member 33" A6NCF5 14 20425852-20436166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 29 "skeletal muscle: 73.3;tongue: 20.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 27.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 21 "dendritic cells: 5.8" "Cell line enriched" "Detected in single" 9 "REH: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049985, HPA056560" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA049985: , HPA056560: AB_2683174" "unprognostic (6.92e-2)" "unprognostic (6.39e-2)" "unprognostic (2.07e-1)" "unprognostic (4.81e-1)" "unprognostic (2.43e-1)" "unprognostic (2.26e-1)" "unprognostic (2.38e-3)" "unprognostic (1.60e-1)" "unprognostic (9.77e-2)" "unprognostic (1.25e-1)" "unprognostic (7.39e-2)" "unprognostic (4.15e-2)" "unprognostic (4.60e-2)" "unprognostic (7.43e-3)" "unprognostic (4.88e-3)" "unprognostic (3.32e-5)" "unprognostic (2.32e-1)" 0.9 0.3 0.5 0.2 0.5 0.2 0.6 1.5 0.6 1.2 0.3 0.8 0.3 1.4 1.0 0.9 0.8 0.8 1.0 0.4 0.5 0.5 0.1 0.4 0.6 0.4 0.6 1.2 0.2 0.5 0.2 0.2 0.4 1.0 0.3 0.3 0.5 1.0 73.3 0.1 0.5 0.5 0.1 0.6 0.3 0.4 0.6 1.0 0.4 20.2 0.6 0.5 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 5.8 0.0 0.1 0.5 0.5 1.5 0.6 0.4 0.5 0.4 0.6 0.4 0.1 0.6 0.7 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 26.5;brain: 21.3" "Group enriched" "Detected in some" 4 "Oligodendrocytes: 286.2;Theca cells: 109.4" "Cancer enriched" "Detected in some" 8 "glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;GAMG: 18.2;HUVEC TERT2: 32.0;NTERA-2: 24.3;SuSa: 17.8;TIME: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029192 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "Centriolar satellite" "HPA029192: AB_10602341" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "unprognostic (5.90e-2)" "unprognostic (1.71e-2)" "unprognostic (1.89e-2)" "unprognostic (5.21e-2)" "unprognostic (2.63e-1)" "unprognostic (5.98e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (8.08e-5)" "unprognostic (2.40e-4)" "unprognostic (1.05e-1)" "unprognostic (5.87e-2)" "unprognostic (7.25e-4)" 1.3 26.5 5.3 0.4 10.2 0.0 0.9 7.3 7.1 1.2 0.6 0.3 0.1 3.0 0.3 0.5 2.5 1.5 0.8 5.2 5.7 1.1 0.6 0.8 0.4 9.6 7.5 7.9 0.3 0.0 0.0 0.1 9.5 0.3 0.3 2.3 0.0 1.4 0.3 0.1 0.3 5.1 7.5 1.3 0.3 7.0 6.7 0.1 0.6 0.3 0.1 0.9 0.2 21.3 0.0 3.6 14.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 18.2 0.0 0.1 0.9 0.0 1.4 0.4 0.0 2.6 0.0 11.0 0.2 0.0 1.6 4.7 6.0 1.3 11.6 32.0 0.0 0.2 2.5 8.1 0.0 0.0 0.0 24.3 0.1 5.7 0.0 8.9 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 17.8 0.0 0.1 34.4 0.0 5.6 0.0 0.5 0.2 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 10.2 7.3 7.1 5.2 5.7 9.6 7.5 9.5 7.5 6.7 21.3 1.7 0.0 0.0 2.0 0.0 0.1 0.0 0.1 0.0 3.6 0.0 0.0 1.5 0.0 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.0 0.7 0.2 0.1 15.0 0.0 0.0 44.4 0.0 0.0 4.4 0.0 0.1 0.0 4.5 14.3 0.2 0.1 0.0 6.6 0.0 0.0 0.3 0.3 1.5 0.9 0.1 0.0 4.7 0.0 1.5 0.0 36.2 286.2 0.1 0.0 1.5 0.1 0.0 0.0 3.4 2.2 4.1 0.0 1.2 0.5 0.4 0.4 0.0 0.3 0.0 0.7 109.4 0.0 0.0 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 74.5;endometrium 1: 170.0" "Cell type enhanced" "Detected in some" "Early spermatids: 17.4;Endometrial stromal cells: 30.8;Granulosa cells: 43.6;Late spermatids: 34.6;Leydig cells: 18.0;Peritubular cells: 12.0" "Cancer enriched" "Detected in many" 8 "testis cancer: 41.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;NTERA-2: 44.4;RPMI-8226: 50.9;SuSa: 25.5" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "CAB025801: , HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (3.78e-2)" "unprognostic (4.10e-3)" "unprognostic (5.79e-3)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (4.87e-2)" "unprognostic (9.75e-4)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (7.98e-2)" "unprognostic (9.14e-3)" "unprognostic (1.15e-1)" "unprognostic (4.69e-2)" "unprognostic (1.90e-4)" "unprognostic (1.64e-3)" 1.8 1.4 0.2 1.1 0.3 0.0 0.7 0.3 0.3 74.5 15.9 1.2 0.3 170.0 12.1 0.1 3.6 0.4 2.6 0.7 0.2 0.4 0.0 2.4 0.2 0.2 0.3 37.8 0.3 0.0 16.0 3.5 0.2 1.5 0.2 0.9 0.1 12.4 0.7 0.3 0.4 36.9 0.2 0.7 0.3 4.5 0.8 0.2 0.1 0.8 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 44.4 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 2.6 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.7 0.2 0.2 0.3 0.2 0.2 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.4 17.4 2.2 30.8 0.6 0.0 0.0 0.0 0.0 0.6 1.4 0.0 0.7 0.0 43.6 0.4 0.0 0.5 0.0 0.1 0.2 0.0 0.0 0.2 34.6 18.0 0.3 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 12.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.3 1.7 6.7 0.4 0.0 0.0 0.0 0.2 0.7 0.0 0.1 LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 130.4" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 80.5;Fibroblasts: 94.2;Hepatocytes: 175.2;Langerhans cells: 66.6;Microglial cells: 129.3" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "K-562: 114.7;RPTEC TERT1: 52.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" NA NA 8240000 14000000 "Cluster 34: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 50: Fibroblasts - ECM organization" "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" 24.3 7.2 5.2 3.9 5.1 5.0 20.6 4.9 6.5 21.5 25.0 5.9 3.9 24.6 6.7 9.2 16.1 14.7 6.9 5.3 12.3 7.8 130.4 22.5 9.5 5.2 5.7 25.0 3.0 2.9 11.7 5.3 5.2 9.0 5.1 2.5 11.9 7.3 2.1 15.1 5.6 18.7 6.3 3.2 13.7 3.9 7.7 4.7 10.4 32.1 5.7 9.1 4.8 5.2 3.3 2.0 2.6 2.9 11.5 10.6 9.0 14.2 8.1 4.8 4.5 1.5 7.6 1.4 10.1 18.0 1.3 2.7 2.2 12.3 12.7 17.2 3.7 18.8 7.9 0.3 7.0 1.4 1.6 29.7 6.8 2.9 10.8 36.2 13.9 1.4 114.7 2.2 22.5 0.9 1.4 0.4 4.2 2.0 0.2 0.4 2.2 0.8 52.3 1.4 1.6 26.3 3.5 1.5 4.0 14.9 5.0 5.0 5.3 4.9 10.0 1.1 7.8 3.0 2.2 0.5 10.2 5.3 4.8 4.5 0.8 1.2 0.5 0.6 0.4 0.2 0.4 0.4 0.7 0.1 0.3 0.5 0.4 0.4 0.7 0.5 1.0 0.7 5.2 5.1 4.9 6.5 5.3 12.3 5.2 5.7 5.2 6.3 7.7 5.2 97.7 0.0 11.3 47.0 2.6 35.3 1.9 3.3 2.2 4.0 3.1 3.3 6.6 11.5 4.2 9.2 0.0 1.6 1.6 0.5 3.9 1.5 1.1 2.0 4.4 80.5 0.0 10.3 20.9 1.1 2.6 94.2 2.6 12.8 1.3 2.6 52.5 175.2 2.0 1.7 21.8 0.8 2.0 6.3 66.6 2.3 34.5 6.1 35.6 129.3 3.4 0.4 2.1 29.1 24.5 1.7 1.9 7.5 2.4 7.5 0.7 6.4 2.6 1.0 0.0 41.1 10.3 1.1 1.2 4.1 29.5 2.6 4.7 3.3 0.8 2.1 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 39.7;choroid plexus: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 242.9;Excitatory neurons: 57.1;Inhibitory neurons: 74.7;Oligodendrocyte precursor cells: 28.6" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;CACO-2: 2.0;NTERA-2: 6.1;SuSa: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" 0.5 1.8 26.8 0.1 31.5 0.0 0.2 23.8 39.7 0.1 44.7 4.0 0.5 0.1 0.0 4.3 0.1 1.0 0.5 29.2 22.6 0.0 2.7 0.0 0.0 29.9 24.2 0.0 0.2 0.0 7.6 0.0 32.9 0.7 2.6 0.4 0.1 0.5 5.9 0.3 1.5 0.6 23.7 0.0 1.8 0.4 26.7 0.0 0.2 3.6 0.1 0.9 0.3 25.2 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.8 31.5 23.8 39.7 29.2 22.6 29.9 24.2 32.9 23.7 26.7 25.2 0.2 0.0 0.0 242.9 0.0 0.3 0.4 0.0 0.0 0.5 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.4 0.0 0.0 57.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 74.7 0.0 0.0 0.0 0.4 1.6 1.5 0.0 0.0 10.3 0.0 0.1 0.0 28.6 3.9 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.2 LHFPL6 "LHFP, MGC22429" ENSG00000183722 "LHFPL tetraspan subfamily member 6" Q9Y693 13 39209116-39603528 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 195.2;Endometrial stromal cells: 78.1;Extravillous trophoblasts: 156.9;Fibroblasts: 113.0;Smooth muscle cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "myeloid DC: 6.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 15 "dendritic cells: 6.2" "Cell line enhanced" "Detected in many" "ASC diff: 255.1;HSkMC: 186.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058975 Approved Approved Nucleoli NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA058975: AB_2683866" "unprognostic (6.98e-2)" "unprognostic (2.71e-1)" "unprognostic (2.00e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (4.10e-2)" "unprognostic (5.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.76e-1)" "unprognostic (5.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (1.20e-7)" "unprognostic (4.41e-3)" "unprognostic (5.25e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (2.30e-4)" 143.2 55.1 46.3 18.6 49.9 1.1 128.7 59.2 45.2 51.6 57.2 51.7 10.8 78.8 47.5 37.0 88.9 74.5 99.7 45.6 57.3 31.9 14.2 82.6 39.1 54.9 56.8 49.6 17.2 18.2 26.9 134.6 51.4 30.8 16.7 11.9 34.7 36.9 32.1 37.9 29.0 68.9 47.8 30.4 27.9 20.4 64.3 17.0 64.2 89.2 17.6 49.1 48.3 44.3 11.5 4.0 118.3 5.1 255.1 115.1 51.6 61.8 88.3 30.8 23.1 0.5 11.6 17.5 1.3 86.6 40.0 17.3 15.0 36.2 25.3 16.9 17.2 47.3 3.7 0.0 26.7 0.8 0.9 186.4 4.7 27.7 45.7 27.6 29.1 1.1 0.0 0.1 59.9 9.9 0.0 14.5 8.8 0.2 15.8 7.7 51.3 0.1 20.9 15.0 0.7 3.8 5.6 7.2 16.8 67.4 6.7 0.1 54.3 77.9 11.7 24.4 33.9 0.9 0.0 48.9 32.4 0.2 57.2 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.3 46.3 49.9 59.2 45.2 45.6 57.3 54.9 56.8 51.4 47.8 64.3 44.3 195.2 3.2 12.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.4 28.6 0.0 0.0 9.9 0.0 0.0 5.0 1.4 0.0 1.9 0.6 0.0 2.7 78.1 32.0 0.0 0.0 0.0 0.6 156.9 113.0 0.0 2.8 2.5 22.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 3.6 2.2 0.0 0.0 0.0 131.6 0.0 0.0 0.0 0.0 6.2 1.2 45.8 0.0 0.0 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LIX1L MGC46719 ENSG00000271601 "Limb and CNS expressed 1 like" Q8IVB5 1 145933423-145958017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063598 Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA063598: AB_2685055" "unprognostic (5.21e-2)" "unprognostic (4.09e-1)" "unprognostic (6.84e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (9.81e-2)" "unprognostic (3.46e-1)" "unprognostic (3.87e-2)" "unprognostic (1.84e-3)" "unprognostic (3.51e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.10e-3)" "unprognostic (4.95e-1)" "unprognostic (1.25e-2)" "prognostic unfavorable (5.27e-4)" 21.0 19.0 14.6 15.2 15.1 6.4 16.0 13.8 13.1 27.1 15.6 23.0 6.7 27.6 11.1 9.8 21.1 15.6 16.3 12.9 13.5 9.8 10.2 15.6 20.4 15.0 15.2 36.9 5.8 7.5 16.3 16.2 14.0 16.2 9.2 19.0 9.4 20.8 34.8 8.1 13.3 25.7 13.9 20.8 11.3 6.6 15.8 16.6 10.8 31.5 20.8 21.1 16.9 15.0 7.3 10.3 31.0 34.5 63.4 53.5 0.4 16.3 29.4 24.8 18.1 0.8 6.7 19.6 17.5 33.1 9.3 0.4 14.6 13.6 23.3 18.2 4.5 10.9 11.0 10.4 20.8 26.2 24.8 32.9 6.2 20.3 29.3 39.9 48.7 25.8 16.4 30.6 39.9 0.2 34.6 21.8 9.0 0.1 13.2 23.2 15.6 32.4 25.7 0.2 11.1 31.6 33.5 0.1 24.9 12.8 1.2 20.3 38.0 41.9 11.5 27.6 27.8 24.5 18.7 19.9 29.5 21.4 20.7 4.0 2.2 3.9 5.7 2.2 7.0 3.0 6.6 5.8 2.1 3.1 6.1 8.0 3.7 3.8 3.8 3.3 5.4 2.6 14.6 15.1 13.8 13.1 12.9 13.5 15.0 15.2 14.0 13.9 15.8 15.0 29.7 0.0 5.8 11.1 23.1 11.3 10.6 10.8 11.4 17.1 3.8 7.5 17.5 14.3 4.9 11.0 8.4 1.4 18.6 2.8 3.9 9.6 10.4 2.3 21.6 36.7 12.6 23.5 5.1 10.0 4.3 28.4 2.6 3.5 5.1 10.8 45.7 19.6 21.1 13.5 6.1 1.4 8.2 24.3 43.8 3.6 35.8 18.8 28.4 15.9 27.4 28.1 35.0 8.5 7.0 11.0 1.2 56.4 17.8 7.5 0.1 7.7 3.0 13.6 26.3 16.8 37.9 24.1 4.7 3.1 7.7 0.8 37.4 21.4 2.1 4.2 LMX1A "LMX1, LMX1.1" ENSG00000162761 "LIM homeobox transcription factor 1 alpha" Q8TE12 1 165201867-165356715 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 20.4" "Group enriched" "Detected in some" 16 "Early spermatids: 30.6;Enteroendocrine cells: 41.9;Late spermatids: 23.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA028051, HPA030088" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA028051: AB_10599731, HPA030088: AB_10601106" "unprognostic (1.73e-1)" "unprognostic (9.57e-2)" "unprognostic (7.58e-2)" "unprognostic (1.59e-1)" "unprognostic (2.17e-1)" "unprognostic (2.82e-1)" "unprognostic (2.63e-1)" "unprognostic (3.22e-2)" "unprognostic (2.10e-3)" "unprognostic (1.51e-1)" "unprognostic (9.82e-3)" 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.3 20.4 0.3 1.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 3.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 1.3 2.5 0.0 0.1 1.0 0.0 0.2 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.7 1.3 0.2 2.1 0.5 0.0 2.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.6 0.2 0.0 0.1 41.9 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 23.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.3;Extravillous trophoblasts: 145.8;Fibroblasts: 76.0;Smooth muscle cells: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cell line enhanced" "Detected in many" "BJ: 66.5;BJ hTERT+: 75.2;hTERT-RPE1: 73.7;U-87 MG: 61.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" No No 280000 "Cluster 35: T-regs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" 12.4 3.1 1.4 5.4 0.8 0.8 6.8 0.2 1.4 12.7 12.3 10.2 1.9 16.0 1.4 4.7 8.3 5.0 27.9 1.7 1.9 8.7 1.5 10.1 4.4 1.4 1.7 8.0 3.3 2.2 9.2 8.0 1.1 15.3 1.4 0.0 7.6 11.9 3.8 6.4 5.6 4.9 0.8 3.2 7.8 2.4 1.9 0.9 5.2 1.9 2.3 16.6 14.8 0.6 3.3 0.0 0.9 0.0 45.6 54.8 2.2 66.5 75.2 27.6 48.7 1.3 1.7 0.0 12.1 49.1 6.9 19.9 0.3 0.2 6.5 0.0 4.3 0.2 2.0 0.3 6.2 0.0 0.1 45.0 0.0 20.8 0.2 73.7 1.0 1.2 0.0 0.3 33.3 2.4 0.4 1.3 6.3 4.4 45.1 0.0 38.7 0.6 2.5 12.0 5.5 0.0 2.0 0.4 0.0 6.5 0.4 0.0 4.9 53.8 47.0 42.8 25.8 0.2 0.0 0.0 61.9 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.9 0.0 1.3 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 3.4 0.2 1.4 0.8 0.2 1.4 1.7 1.9 1.4 1.7 1.1 0.8 1.9 0.6 4.1 0.0 0.6 3.3 0.1 5.9 7.6 6.0 4.0 0.9 2.3 4.8 92.3 2.8 0.9 9.2 0.0 2.2 0.6 0.1 3.9 5.2 1.7 9.2 8.0 4.1 3.5 0.0 0.5 1.3 145.8 76.0 8.6 9.3 1.3 5.5 12.1 0.1 6.6 0.0 0.4 0.6 2.0 0.0 6.2 1.3 9.9 0.9 10.6 0.0 0.1 6.4 0.0 1.5 0.3 12.2 0.1 21.1 0.1 4.8 0.4 2.5 1.2 0.4 0.0 6.0 32.7 8.9 4.9 2.4 3.4 5.1 3.4 0.3 1.1 5.0 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;cervix: 10.1;parathyroid gland: 11.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 873.9;Inhibitory neurons: 581.5;Oligodendrocyte precursor cells: 296.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 16.4;HSkMC: 3.1;RPTEC TERT1: 5.2;SCLC-21H: 8.8;U-138 MG: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" 1.4 2.2 5.3 1.0 7.5 0.0 1.4 0.0 16.5 10.1 0.0 2.0 0.2 2.5 0.6 0.5 3.3 1.0 0.6 7.9 5.9 0.2 0.3 0.7 0.0 0.8 1.4 1.6 0.3 11.1 0.8 1.1 4.9 2.4 1.0 2.6 0.3 6.4 0.2 0.6 0.4 1.5 0.8 0.6 0.7 0.9 2.0 0.3 0.5 0.5 0.2 6.1 5.2 4.3 0.0 0.0 1.7 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 8.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.5 0.0 16.5 7.9 5.9 0.8 1.4 4.9 0.8 2.0 4.3 0.5 0.0 0.0 29.7 0.0 0.3 0.0 0.0 0.0 8.2 0.1 0.6 1.0 2.8 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.2 0.3 7.8 0.9 0.0 0.0 873.9 0.0 0.1 7.9 0.0 0.6 0.0 0.2 0.0 0.5 0.1 0.0 581.5 0.0 0.0 0.0 0.8 1.7 8.4 0.1 1.8 24.4 0.0 0.4 0.0 296.1 11.8 0.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.4 1.5 0.0 2.1 0.0 0.3 0.1 0.2 2.1 0.0 0.1 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRN4CL ENSG00000177363 "LRRN4 C-terminal like" Q8ND94 11 62686406-62689530 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 62.1;Leydig cells: 27.1;Melanocytes: 33.8;Peritubular cells: 17.3;Skeletal myocytes: 33.0" "Cancer enriched" "Detected in many" 5 "melanoma: 26.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.7;ASC TERT1: 25.3;HHSteC: 19.8;HSkMC: 10.6;LHCN-M2: 13.4" "Low region specificity" "Detected in many" HPA050317 Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA050317: AB_2681084" "unprognostic (1.28e-1)" "unprognostic (2.74e-2)" "unprognostic (2.84e-1)" "unprognostic (9.95e-3)" "unprognostic (2.61e-2)" "unprognostic (4.03e-3)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (3.04e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-7)" "unprognostic (2.73e-2)" "unprognostic (6.12e-2)" "unprognostic (4.53e-3)" "unprognostic (1.86e-2)" 23.3 6.6 0.4 2.5 0.4 0.5 16.0 1.5 1.3 22.4 2.6 15.1 1.8 29.7 3.7 4.5 18.2 3.6 7.2 0.6 0.6 1.0 0.1 3.5 0.5 0.5 0.3 21.0 1.1 0.3 1.7 0.7 0.4 6.1 2.1 0.4 5.5 5.8 4.8 10.6 7.2 9.1 0.2 0.2 8.2 1.5 0.5 0.4 4.2 5.6 0.3 9.7 16.1 0.7 0.0 0.1 0.2 0.3 7.7 25.3 0.3 2.8 4.0 0.3 1.4 0.2 0.1 0.2 0.3 4.6 0.1 0.3 0.1 0.0 0.4 0.2 0.2 0.5 0.2 0.2 19.8 0.2 0.2 10.6 0.1 0.6 0.0 0.2 0.1 0.4 0.3 0.1 13.4 0.1 0.3 0.6 0.6 0.1 0.1 0.1 1.7 0.3 0.0 0.2 0.8 0.3 0.4 0.3 0.8 0.1 0.2 0.3 0.3 2.4 0.2 2.7 0.1 0.2 0.2 0.3 1.5 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.1 0.0 0.0 0.4 0.4 1.5 1.3 0.6 0.6 0.5 0.3 0.4 0.2 0.5 0.7 4.0 0.0 1.8 0.0 0.1 6.6 2.1 0.0 0.0 2.1 0.5 0.8 1.5 0.0 0.6 0.0 2.1 0.1 0.2 0.0 0.0 0.0 1.0 0.5 11.0 3.7 1.2 0.0 0.1 0.0 0.2 62.1 0.5 0.4 1.3 0.2 1.4 0.1 0.4 1.7 0.3 0.3 0.0 0.6 8.3 0.5 27.1 1.1 33.8 1.9 0.1 0.2 1.0 0.0 0.1 0.0 0.1 17.3 0.4 1.4 0.1 0.3 0.0 1.0 0.0 33.0 2.8 0.4 0.3 0.5 7.0 0.1 1.1 1.2 0.1 1.3 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 739.0;placenta: 535.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 966.4;Fibroblasts: 2136.1;Leydig cells: 401.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "cerebral cortex: 5.6" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cell line enriched" "Detected in some" 5 "BJ hTERT+: 1991.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 149.2" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" NA NA 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" 161.5 133.5 0.6 68.1 0.7 0.3 153.2 0.6 5.6 199.8 4.2 85.0 56.1 301.0 88.3 75.7 59.2 739.0 183.8 0.7 0.9 85.0 34.6 211.4 41.3 0.9 0.8 92.9 72.9 26.3 5.3 535.9 0.8 115.2 133.0 5.7 14.3 67.4 9.6 20.0 90.6 354.5 0.7 4.8 47.1 17.5 1.3 13.4 30.8 73.0 80.3 486.0 39.2 0.8 0.0 0.3 6.9 0.0 237.4 115.9 0.7 400.8 1991.0 16.0 24.3 0.0 0.1 0.0 0.0 339.9 0.0 0.6 0.0 0.0 5.4 0.0 0.0 0.0 21.5 0.0 183.7 0.6 0.1 160.5 0.0 33.7 1.0 0.9 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 1.2 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.3 14.9 0.1 0.0 10.8 16.3 0.0 0.0 0.0 17.0 4.5 14.3 0.0 0.2 0.0 0.0 8.8 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.6 5.6 0.7 0.9 0.9 0.8 0.8 0.7 1.3 0.8 77.5 12.8 30.9 0.0 0.6 97.6 1.2 0.8 3.4 0.2 9.4 8.6 15.2 0.0 5.0 0.0 2.1 44.9 4.0 0.1 0.0 0.7 3.5 27.0 966.4 27.2 0.0 0.0 0.0 0.0 38.9 2136.1 8.6 15.2 18.3 0.0 55.0 0.3 63.6 0.0 0.2 0.3 0.0 0.3 143.5 8.7 401.7 9.5 117.4 16.9 1.0 86.9 0.0 0.0 0.0 2.1 0.0 44.8 6.3 4.9 0.4 0.3 0.8 3.0 0.0 39.1 165.5 0.2 0.9 5.9 100.2 84.0 14.5 27.4 0.0 4.1 MALRD1 "bA265G8.2, C10orf112, Diet1" ENSG00000204740 "MAM and LDL receptor class A domain containing 1" Q5VYJ5 10 19048801-19790401 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 31.1" "Group enriched" "Detected in some" 4 "Astrocytes: 37.9;Oligodendrocyte precursor cells: 76.4;Proximal enterocytes: 69.3" "Cancer enhanced" "Detected in some" "breast cancer: 0.9;stomach cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "Karpas-707: 44.2" "Not detected" "Not detected" "HPA035732, HPA038106, HPA046848" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "HPA035732: AB_2674756, HPA038106: AB_2675836, HPA046848: AB_2679837" "unprognostic (9.03e-3)" "unprognostic (1.38e-1)" "unprognostic (2.40e-2)" "unprognostic (4.05e-3)" "unprognostic (2.49e-1)" "unprognostic (3.77e-1)" "unprognostic (2.74e-2)" "unprognostic (5.57e-2)" "unprognostic (5.01e-1)" "unprognostic (1.00e-1)" "unprognostic (3.55e-1)" "unprognostic (7.69e-2)" "unprognostic (3.16e-2)" "unprognostic (9.80e-2)" "unprognostic (8.90e-2)" "unprognostic (3.13e-2)" "unprognostic (3.78e-4)" 0.5 0.7 1.9 0.2 1.9 0.4 0.6 1.0 1.6 0.7 1.3 0.5 30.6 0.6 2.2 0.2 0.2 0.4 1.4 1.8 2.1 1.5 0.1 0.9 0.1 1.5 1.7 1.2 0.1 0.0 1.5 0.4 1.5 0.6 0.1 0.3 0.1 0.3 0.6 0.2 31.1 0.4 1.7 0.2 0.3 2.1 1.9 1.9 0.5 0.1 0.0 0.6 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.8 0.0 2.6 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 44.2 0.0 4.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.9 1.9 1.0 1.6 1.8 2.1 1.5 1.7 1.5 1.7 1.9 1.5 0.0 0.0 1.8 37.9 0.0 0.4 0.2 0.0 0.0 0.1 0.1 0.6 1.6 0.0 0.0 0.0 0.0 0.8 1.3 0.0 1.9 0.1 7.9 0.1 0.3 0.1 0.0 4.2 11.6 0.0 0.8 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 11.0 9.5 0.0 0.0 0.3 1.8 0.0 0.0 0.0 5.6 0.0 1.4 0.0 76.4 4.9 0.0 13.8 0.7 0.0 0.2 69.3 0.2 0.0 0.0 0.0 0.1 0.2 9.0 4.1 0.1 0.1 0.3 0.0 1.9 9.7 0.0 MAMSTR "FLJ36070, MASTR" ENSG00000176909 "MEF2 activating motif and SAP domain containing transcriptional regulator" Q6ZN01 19 48712725-48719725 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 32.4;skeletal muscle: 88.9;tongue: 22.6" "Cell type enhanced" "Detected in many" "Theca cells: 10.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 7.0" "Region enhanced" "Detected in many" "cerebellum: 7.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 7.2;RH-30: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049765 Approved "Nuclear speckles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Nuclear speckles" "HPA049765: AB_2680870" "unprognostic (6.00e-2)" "unprognostic (3.20e-2)" "unprognostic (5.98e-2)" "unprognostic (6.07e-2)" "unprognostic (1.65e-1)" "unprognostic (6.50e-3)" "unprognostic (4.34e-4)" "unprognostic (2.11e-2)" "unprognostic (4.69e-1)" "unprognostic (2.69e-2)" "unprognostic (2.89e-2)" "unprognostic (4.65e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (2.79e-1)" "unprognostic (4.84e-2)" "unprognostic (1.39e-2)" 4.6 32.4 1.7 0.8 2.0 0.3 1.8 7.9 3.7 6.2 0.0 2.5 0.6 8.0 1.4 3.5 8.0 1.0 4.0 2.0 0.2 2.4 0.4 1.4 0.6 0.6 0.8 8.7 1.9 3.0 3.8 1.6 0.9 2.4 0.7 0.5 2.9 1.9 88.9 2.1 1.2 4.6 0.2 6.1 1.6 9.2 0.6 0.5 1.2 22.6 0.6 2.0 4.6 1.2 0.5 1.3 1.4 3.5 2.7 4.5 1.3 4.8 3.8 2.3 3.6 1.4 0.9 0.7 0.2 4.4 1.3 1.0 0.1 0.8 0.9 0.5 1.6 0.3 0.6 7.2 1.4 0.1 0.9 2.8 0.9 3.2 0.4 3.1 0.8 1.3 0.3 0.9 1.5 0.6 1.1 0.5 0.1 1.1 1.0 1.3 16.6 0.4 0.2 0.3 1.5 2.8 0.7 0.3 0.3 0.3 0.5 0.0 0.3 4.7 0.8 3.8 0.6 1.0 0.6 0.5 1.7 0.5 0.9 0.0 0.2 0.5 1.6 0.4 1.0 1.3 1.7 1.6 0.4 2.1 1.6 1.5 0.2 0.3 0.4 1.3 0.8 0.3 1.7 2.0 7.9 3.7 2.0 0.2 0.6 0.8 0.9 0.2 0.6 1.2 2.4 0.0 0.0 2.6 1.3 0.9 1.8 1.5 4.6 1.8 1.4 2.2 2.9 0.0 2.3 1.8 2.1 0.8 0.5 0.6 5.9 1.7 0.8 0.8 3.5 3.8 0.0 1.3 2.9 1.0 2.9 4.9 1.1 1.6 0.0 6.1 4.6 0.3 1.1 0.0 2.0 0.7 2.0 0.3 2.2 1.7 5.6 1.6 7.2 0.0 1.2 5.3 2.1 1.5 1.2 0.5 0.0 6.0 1.5 0.6 1.1 0.6 0.4 2.9 0.0 5.1 4.7 0.7 1.6 2.4 0.9 1.0 1.8 10.1 0.8 1.6 MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 317.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 120.6;granulocytes: 137.8;Hepatocytes: 221.1;Peritubular cells: 95.2;Proximal enterocytes: 178.8;Proximal tubular cells: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 41.4;SiHa: 78.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" 78.0 51.1 99.3 6.5 102.8 0.1 45.7 89.1 117.7 32.3 83.5 46.5 73.5 119.4 55.0 31.4 98.0 17.3 97.8 93.9 149.1 124.2 317.6 33.0 6.1 143.8 134.2 155.4 10.9 15.6 25.9 11.2 125.9 82.9 16.5 13.9 78.5 155.5 114.6 9.9 79.0 103.3 115.8 2.4 23.7 9.0 145.2 3.8 5.6 65.1 7.1 28.3 25.4 115.8 0.0 1.0 0.1 0.0 0.6 0.1 0.3 0.0 0.0 0.0 0.0 5.4 4.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 8.1 41.4 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.3 3.5 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.1 1.1 78.2 0.0 0.5 0.6 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 99.3 102.8 89.1 117.7 93.9 149.1 143.8 134.2 125.9 115.8 145.2 115.8 5.9 0.0 4.1 53.5 0.4 5.5 0.4 1.2 1.8 1.4 3.5 22.4 120.6 52.9 1.9 5.5 4.2 0.4 0.0 10.2 62.6 20.1 0.4 26.4 81.6 10.3 0.0 2.7 36.9 2.8 0.5 17.0 16.3 6.0 137.8 69.6 7.5 221.1 1.5 15.2 7.6 6.4 12.2 4.3 3.6 2.1 46.0 1.8 7.2 9.4 0.0 27.2 0.0 11.6 1.3 7.9 7.8 95.2 0.3 0.6 178.8 182.6 11.8 1.0 13.1 2.6 18.4 0.3 0.4 2.3 4.0 0.4 5.5 0.5 10.5 0.5 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 85.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 55.9;HHSteC: 53.7;HSkMC: 51.8;hTERT-RPE1: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 12.6 7.6 12.9 5.4 15.2 3.2 10.3 25.9 19.6 23.5 4.3 13.3 3.2 22.9 4.8 4.0 18.5 14.0 8.6 15.6 11.3 8.5 1.7 11.2 4.4 11.9 11.1 21.6 3.6 7.3 22.7 6.4 13.2 9.6 3.8 13.6 4.9 10.9 2.7 5.7 8.9 14.4 8.0 9.0 7.3 9.0 13.0 6.0 8.6 6.3 2.7 14.0 12.2 13.7 0.5 15.1 8.6 14.2 55.9 28.9 1.2 10.1 18.9 10.8 11.0 0.3 1.8 3.5 5.4 10.8 8.7 0.1 4.3 6.8 4.3 4.9 5.4 3.5 8.3 0.0 53.7 0.1 3.6 51.8 5.2 14.6 7.8 69.1 16.9 7.8 0.1 15.7 10.0 6.7 3.8 0.9 3.2 0.0 5.5 5.4 6.3 1.0 5.4 0.1 9.3 12.4 5.6 6.8 14.9 1.8 4.6 10.3 12.9 10.2 10.8 4.5 2.5 6.1 8.0 0.0 16.8 6.9 10.4 0.0 0.5 0.0 0.4 0.4 0.8 0.1 0.5 0.6 0.2 0.0 0.2 0.3 1.0 0.2 0.1 0.0 0.1 0.1 12.9 15.2 25.9 19.6 15.6 11.3 11.9 11.1 13.2 8.0 13.0 13.7 11.4 6.4 14.6 21.5 8.1 0.8 2.4 0.5 4.6 28.9 5.6 5.2 0.8 7.2 6.4 1.8 37.5 1.9 12.2 4.8 9.8 6.7 1.5 11.5 27.6 10.4 3.5 1.3 21.1 1.8 2.2 11.0 2.0 15.8 12.7 7.0 15.0 7.8 4.1 30.3 19.1 2.8 2.0 10.3 2.2 1.8 8.1 8.6 0.0 8.4 8.5 19.9 5.2 10.6 11.0 4.4 2.1 8.2 6.7 5.3 7.1 14.8 5.5 85.0 6.6 23.5 10.2 2.5 2.1 2.5 1.0 2.2 11.6 12.5 4.1 3.9 MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 163.3;Oligodendrocytes: 435.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced Uncertain Nucleoplasm NA NA 13000000 "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016738: AB_1853571, HPA016739: AB_1853570" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (2.55e-2)" "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (8.53e-2)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.93e-2)" "unprognostic (5.40e-2)" "unprognostic (2.22e-3)" "unprognostic (5.83e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (3.99e-3)" 22.4 58.7 54.2 29.1 65.2 22.1 16.6 58.5 89.4 19.3 1.9 24.5 15.0 14.0 18.9 17.4 12.7 41.1 89.1 68.8 56.9 18.4 33.4 27.2 35.8 74.0 61.0 24.9 12.8 19.2 16.3 28.3 70.6 16.1 24.6 49.1 20.2 17.2 50.4 26.1 19.6 23.8 70.0 27.8 30.6 6.4 68.2 74.4 21.7 91.9 32.6 27.2 14.4 109.0 0.8 26.3 28.9 15.4 17.1 15.9 2.0 18.7 44.7 22.3 37.2 2.0 9.9 87.8 21.3 41.1 23.5 35.0 22.8 15.2 39.8 51.5 21.3 88.9 26.9 52.8 12.6 49.5 72.3 19.6 4.0 30.4 10.5 21.2 124.0 61.4 28.3 37.7 28.8 1.7 104.6 16.4 22.5 28.8 5.2 41.6 35.2 20.0 11.9 0.4 35.9 23.9 14.0 0.7 15.5 27.2 3.2 29.0 21.0 24.1 13.4 14.2 12.7 19.9 50.8 50.8 41.4 65.1 38.2 69.0 30.0 46.7 63.8 37.7 49.5 60.8 44.4 58.3 33.4 55.5 50.6 61.5 21.5 74.4 51.6 47.3 52.9 76.9 54.2 65.2 58.5 89.4 68.8 56.9 74.0 61.0 70.6 70.0 68.2 109.0 27.0 22.4 18.3 104.8 73.0 23.7 5.1 2.0 38.1 109.6 18.9 19.7 105.6 12.8 4.8 5.5 25.0 0.6 107.9 13.3 5.9 9.8 12.4 11.9 12.6 29.4 29.3 25.0 163.3 12.8 9.7 28.5 42.3 14.6 27.3 4.6 33.5 26.1 26.1 52.2 141.7 25.8 4.1 44.7 38.3 6.8 19.3 44.6 30.2 70.3 17.1 40.3 52.5 97.5 435.9 10.1 15.6 21.1 31.6 2.9 12.0 5.1 6.5 12.5 78.9 25.4 74.9 1.9 10.6 9.1 27.6 0.8 76.1 15.0 11.1 3.5 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Fibroblasts: 8.5;Langerhans cells: 6.3;Spermatogonia: 4.9;Suprabasal keratinocytes: 4.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 2.5;U-937: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 14000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" 0.7 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 24.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.4 0.0 3.2 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 6.4 0.7 1.0 0.0 0.0 1.6 1.9 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.5 0.1 0.7 0.2 0.4 0.0 0.0 1.0 2.5 0.0 8.5 1.1 0.8 0.0 0.3 0.4 0.2 0.1 0.0 0.4 0.1 0.0 0.0 6.3 0.5 0.0 0.1 1.8 1.0 0.0 0.0 0.0 3.0 0.4 0.9 0.1 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.4 0.4 1.6 4.9 0.3 4.3 0.3 0.3 0.1 0.2 1.0 MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692131-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 53.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 68.3;Inhibitory neurons: 65.6;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favorable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" 6.1 3.8 2.8 7.4 2.5 19.9 5.7 10.4 3.6 8.3 6.4 28.7 27.8 8.9 3.0 14.2 10.8 12.7 7.8 3.9 2.8 10.6 7.0 10.2 4.9 3.4 3.2 4.9 5.5 10.0 1.9 12.8 3.2 5.8 30.8 2.3 6.7 5.7 41.8 6.8 24.5 13.5 3.0 5.0 43.2 4.3 3.3 5.7 6.4 53.7 7.7 14.9 5.1 2.8 41.7 66.1 16.8 12.2 25.0 28.0 17.1 25.0 35.5 24.5 26.0 39.6 38.6 17.7 19.6 30.8 13.3 36.9 22.2 29.8 32.5 19.5 20.8 22.1 23.5 22.1 19.5 56.0 17.9 28.7 24.9 22.0 46.6 38.4 29.8 18.5 14.0 12.9 23.0 24.3 15.2 12.0 18.5 45.2 13.6 15.7 35.8 4.7 32.7 22.4 17.8 7.9 30.8 34.1 7.5 20.2 6.8 14.5 24.3 11.8 19.9 25.7 16.9 9.4 12.8 12.1 15.8 27.5 9.2 1.8 6.7 18.6 3.0 7.3 3.1 3.5 2.9 3.6 5.8 1.7 2.3 2.6 8.8 2.2 8.9 2.0 5.2 4.2 2.8 2.5 10.4 3.6 3.9 2.8 3.4 3.2 3.2 3.0 3.3 2.8 13.7 35.3 17.0 21.2 4.2 11.7 14.4 8.9 10.8 3.0 5.9 3.9 6.6 8.6 22.0 18.4 2.1 7.3 4.8 38.2 1.9 11.1 14.5 23.3 9.9 9.7 8.4 10.8 58.2 25.2 10.1 7.2 68.3 26.4 8.2 3.4 8.9 5.8 6.7 0.0 65.6 28.2 12.2 6.0 2.9 7.2 5.3 6.7 8.8 37.5 5.7 5.4 2.1 72.4 40.3 40.7 15.6 4.1 5.7 9.7 19.8 8.6 22.6 3.9 13.1 6.8 12.1 5.1 5.2 6.2 12.4 9.3 5.0 12.7 24.5 26.8 MEOX2 "GAX, MOX2" ENSG00000106511 "Mesenchyme homeobox 2" P50222 7 15611212-15686683 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.9;placenta: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 84.7;Endothelial cells: 37.2;Leydig cells: 40.4;Peritubular cells: 25.2;Sertoli cells: 26.3;Smooth muscle cells: 27.0" "Cancer enriched" "Detected in many" 8 "glioma: 15.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AN3-CA: 248.8;U-138 MG: 62.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "medulla oblongata: 3.5;spinal cord: 9.5" HPA053793 Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA053793: AB_2682264" "unprognostic (1.10e-1)" "unprognostic (4.72e-2)" "unprognostic (9.82e-3)" "unprognostic (4.22e-2)" "unprognostic (2.35e-2)" "unprognostic (1.36e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-3)" "unprognostic (4.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.65e-5)" "unprognostic (3.67e-3)" "unprognostic (1.13e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-4)" 37.9 1.1 0.6 2.9 0.3 0.0 26.2 0.3 0.7 4.3 0.2 5.7 0.4 2.9 2.4 2.4 5.0 6.1 11.8 0.3 0.7 0.5 0.7 12.9 9.1 2.2 0.9 2.4 1.6 1.2 1.2 42.1 1.0 1.9 1.9 0.2 4.4 1.5 9.9 6.9 2.2 4.5 0.7 0.9 2.3 2.3 1.0 3.3 8.6 13.3 5.3 6.1 4.8 0.5 0.0 0.0 0.0 248.8 2.4 8.5 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 62.9 0.0 25.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.3 0.7 0.3 0.7 2.2 0.9 1.0 0.7 1.0 0.5 84.7 0.0 0.5 0.7 0.3 8.2 0.0 0.0 0.6 0.0 0.5 1.3 2.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 37.2 0.0 0.0 3.8 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 3.7 0.0 0.0 0.0 9.6 0.2 40.4 0.3 3.6 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 25.2 0.0 0.1 0.0 0.0 0.0 0.0 26.3 1.5 27.0 0.1 0.1 0.1 7.0 0.1 0.8 0.7 0.0 0.0 METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110245928-110358272 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 14.2" "Group enriched" "Detected in some" 4 "Astrocytes: 30.0;Excitatory neurons: 23.8;Inhibitory neurons: 28.7;Late spermatids: 8.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 29 "T-cells: 3.5" "Cell line enhanced" "Detected in some" "HHSteC: 1.0;SCLC-21H: 1.6;SuSa: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" 1.8 1.6 1.4 1.6 2.3 0.0 1.7 2.1 1.9 3.9 8.1 5.9 1.4 7.5 2.2 4.0 6.0 5.8 3.0 1.7 1.8 3.9 0.9 1.6 0.1 1.6 2.2 5.6 1.3 2.5 2.1 0.4 1.4 4.9 4.2 1.4 0.4 7.1 0.0 0.5 2.1 14.2 2.0 0.7 2.4 2.1 1.8 1.0 1.3 1.1 0.6 4.7 1.6 1.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.3 2.1 1.9 1.7 1.8 1.6 2.2 1.4 2.0 1.8 1.2 0.0 0.0 0.0 30.0 0.3 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.9 0.4 1.5 0.1 0.0 0.0 23.8 0.0 0.0 0.8 0.0 0.4 0.0 0.5 0.0 0.0 0.0 1.7 28.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 3.7 0.0 0.6 0.0 31.7 5.4 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.3 2.1 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Fibroblasts: 903.5;Peritubular cells: 240.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 394.8;ASC TERT1: 597.9;fHDF/TERT166: 284.0;HHSteC: 275.4;HSkMC: 417.8;MOLT-4: 375.8;SH-SY5Y: 350.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" 271.8 81.9 6.5 74.0 10.0 2.7 197.7 7.0 9.5 326.1 13.1 287.5 102.0 237.3 289.0 293.2 227.5 646.2 273.2 6.1 8.3 61.4 45.6 634.7 65.7 7.7 9.0 325.8 71.3 7.0 87.5 156.7 6.6 226.7 139.1 17.3 108.1 129.8 41.6 144.7 187.6 262.7 6.9 59.8 176.1 31.8 8.1 42.4 114.5 249.7 78.6 488.8 244.6 6.9 0.3 0.7 0.6 0.1 394.8 597.9 0.8 44.8 160.0 4.6 3.2 0.2 0.0 0.2 0.1 284.0 0.1 0.2 0.1 0.0 0.8 0.3 1.2 0.0 0.3 0.0 275.4 14.4 0.2 417.8 0.0 2.6 0.1 4.7 0.0 3.9 0.1 0.0 0.4 0.0 375.8 33.8 7.1 0.1 0.4 26.4 24.9 0.7 0.0 0.2 35.8 350.2 0.4 0.2 0.3 2.4 0.4 82.4 0.2 50.9 3.3 2.3 0.1 0.4 0.5 0.1 48.9 15.4 0.1 0.0 0.1 1.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 6.5 10.0 7.0 9.5 6.1 8.3 7.7 9.0 6.6 6.9 8.1 6.9 35.1 3.2 12.1 0.0 0.3 47.5 0.7 0.2 5.7 0.7 2.3 4.2 10.7 0.0 3.1 1.8 0.0 7.2 1.3 0.0 0.0 0.2 0.7 0.3 21.4 15.9 0.0 0.0 0.0 0.0 3.6 903.5 6.1 0.4 1.3 0.1 15.4 0.2 9.4 0.0 0.0 0.0 0.0 0.0 62.9 6.3 78.3 3.9 67.6 14.0 0.0 80.2 0.0 0.5 0.1 0.1 0.0 240.0 2.6 2.2 0.0 0.0 2.9 3.3 19.7 38.6 103.1 0.4 0.5 8.8 41.1 19.4 6.9 0.2 0.0 2.2 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MNS1 "FLJ11222, SPATA40" ENSG00000138587 "Meiosis specific nuclear structural 1" Q8NEH6 15 56421544-56465137 "Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.2;testis: 48.2" "Group enriched" "Detected in many" 5 "Early spermatids: 504.6;Endometrial ciliated cells: 256.5;Respiratory ciliated cells: 232.5;Spermatocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039975, HPA040382" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear speckles" "HPA039975: AB_10793858, HPA040382: AB_10794740" "unprognostic (7.78e-2)" "unprognostic (2.54e-2)" "unprognostic (1.19e-1)" "unprognostic (5.07e-2)" "unprognostic (2.25e-1)" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-2)" "unprognostic (2.05e-2)" "unprognostic (6.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-3)" "unprognostic (8.20e-3)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.71e-2)" 1.9 1.4 2.6 1.6 2.4 4.6 3.1 10.1 2.9 3.5 12.3 1.9 2.3 3.6 1.3 2.7 21.2 3.3 2.5 2.2 2.4 10.5 1.9 3.4 1.3 7.2 6.8 4.0 2.4 0.6 3.5 1.6 5.1 2.3 2.0 4.7 2.0 1.7 1.0 1.4 2.1 1.3 6.1 1.4 2.2 48.2 2.7 5.6 2.9 1.1 1.2 1.3 2.5 3.9 32.1 7.4 3.8 11.3 3.1 6.7 0.7 7.6 4.4 8.8 18.6 10.5 15.0 17.8 9.4 3.2 12.8 12.3 4.7 4.4 17.9 0.0 1.9 22.9 8.8 1.8 1.1 7.9 2.4 2.7 0.2 17.9 2.6 3.7 1.6 6.8 5.2 0.0 7.6 4.2 0.3 9.8 1.2 16.4 4.3 15.0 22.6 0.2 8.7 6.1 29.5 8.9 12.7 3.8 13.6 0.9 9.1 12.1 0.7 12.0 13.6 11.6 18.8 3.6 11.9 0.3 13.4 18.3 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 10.1 2.9 2.2 2.4 7.2 6.8 5.1 6.1 2.7 3.9 0.7 0.0 4.7 1.0 0.8 3.3 8.8 9.3 1.8 10.5 4.7 8.3 6.0 4.3 28.3 35.0 25.0 1.8 0.2 3.7 11.7 10.9 504.6 256.5 7.8 2.0 1.2 3.0 4.9 1.9 3.9 14.0 5.1 7.2 0.0 11.0 6.8 0.4 7.0 15.2 3.7 4.5 10.2 1.0 5.5 60.8 12.8 2.0 0.0 0.0 0.8 12.4 0.0 1.5 2.8 1.2 0.1 8.6 0.5 3.0 0.3 12.3 232.5 32.6 0.0 21.6 6.5 249.6 25.0 7.1 1.4 0.5 1.0 6.4 6.0 3.5 MRC2 "CD280, CLEC13E, ENDO180, KIAA0709" ENSG00000011028 "Mannose receptor C type 2" Q9UBG0 17 62627670-62693597 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 93.9;Endometrial stromal cells: 65.2;Fibroblasts: 141.6;Late spermatids: 82.8;Leydig cells: 71.7;Peritubular cells: 102.3;Theca cells: 71.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 210.9;fHDF/TERT166: 164.9;HSkMC: 148.6;hTERT-RPE1: 150.6;U-138 MG: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041991 Enhanced NA NA 36000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA041991: AB_10794166" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (4.45e-2)" "unprognostic (2.59e-2)" "unprognostic (4.29e-2)" "unprognostic (2.67e-2)" "unprognostic (6.21e-2)" "unprognostic (1.80e-1)" "unprognostic (7.39e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (7.70e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (5.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.00e-2)" "unprognostic (1.93e-2)" 24.5 8.6 4.8 13.7 7.9 5.3 16.2 5.6 5.3 39.3 22.5 12.3 6.6 31.3 9.6 21.2 26.3 32.4 45.2 4.3 5.1 18.1 2.8 35.0 4.5 9.3 9.1 45.8 7.5 1.2 17.4 9.6 8.9 25.7 3.2 0.7 9.0 20.8 12.2 28.8 10.9 21.3 9.9 16.3 9.0 16.2 6.0 4.5 7.0 6.5 2.0 17.9 28.2 11.2 0.1 35.1 23.3 29.7 64.1 115.4 3.1 210.9 138.8 34.3 40.8 2.1 0.4 0.0 15.2 164.9 15.1 17.8 4.0 19.0 8.8 26.7 5.4 17.6 27.2 0.0 97.2 22.9 0.2 148.6 9.5 29.6 3.4 150.6 15.4 10.6 9.3 0.0 47.8 6.3 6.6 70.6 4.9 0.0 2.4 22.3 15.4 0.2 3.2 0.4 2.9 52.2 14.1 0.4 0.3 14.3 0.6 97.1 68.5 216.6 83.9 36.2 43.6 0.2 0.0 0.0 66.8 22.6 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.8 7.9 5.6 5.3 4.3 5.1 9.3 9.1 8.9 9.9 6.0 11.2 8.6 3.2 35.9 5.9 0.4 11.3 5.8 20.7 25.0 11.1 1.6 11.4 4.4 0.0 2.3 1.8 0.0 0.7 0.6 0.1 0.0 0.3 93.9 22.6 65.2 5.2 0.0 28.4 3.3 0.2 2.7 141.6 2.0 2.9 2.5 13.8 5.3 0.0 6.8 0.0 0.9 0.1 0.0 9.2 11.1 82.8 71.7 7.0 5.4 57.1 0.6 0.8 1.0 3.5 0.9 0.6 0.0 102.3 0.3 2.1 0.0 0.0 1.4 0.6 0.0 31.4 23.3 11.7 9.3 34.6 7.7 1.9 2.7 71.0 0.2 1.4 MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802636-21937651 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046915, CAB080036, CAB080037" Approved Supported Nucleoplasm,Cytosol NA NA 3000000 "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "CAB080036: AB_11128130, CAB080037: AB_11129069, HPA046915: AB_2679862" "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (2.21e-1)" "unprognostic (2.58e-3)" "unprognostic (2.78e-1)" "unprognostic (6.16e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (9.47e-2)" "unprognostic (2.03e-1)" "unprognostic (8.63e-2)" "unprognostic (4.76e-3)" "unprognostic (4.27e-2)" "unprognostic (6.28e-3)" "unprognostic (2.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" 5.9 6.5 4.1 5.4 4.8 5.8 8.5 4.2 5.7 7.8 7.6 6.7 4.8 8.8 7.1 8.8 7.1 4.9 7.0 3.8 4.0 6.9 10.9 5.8 6.3 5.0 4.5 12.1 6.6 8.4 2.8 8.9 5.1 7.2 8.0 3.9 6.5 7.0 4.5 7.0 5.9 9.0 4.0 7.3 7.2 2.9 5.4 6.8 7.2 5.4 7.3 10.1 7.4 6.0 30.4 1.0 23.0 19.0 19.4 19.0 28.3 42.3 21.0 21.9 24.3 21.7 14.6 15.3 13.4 21.1 16.3 15.2 24.4 59.5 36.8 0.3 19.8 0.3 56.8 28.8 18.6 24.5 26.3 23.5 0.1 38.6 42.6 24.4 22.6 0.5 0.3 20.1 21.9 3.1 26.8 0.7 27.5 14.7 35.2 0.4 18.0 26.0 18.3 0.4 14.4 15.3 14.4 17.1 21.1 17.9 10.9 0.6 23.8 0.3 15.7 0.2 34.4 13.7 25.5 30.0 0.2 24.3 12.0 1.2 5.6 0.2 3.6 4.5 6.1 5.9 5.3 4.2 6.9 8.4 4.6 4.2 0.7 6.7 2.9 6.3 3.2 2.7 4.1 4.8 4.2 5.7 3.8 4.0 5.0 4.5 5.1 4.0 5.4 6.0 18.8 22.4 19.8 26.1 16.3 14.1 58.4 22.4 16.5 0.0 20.2 23.9 22.4 24.3 27.9 14.7 0.0 52.3 11.4 6.8 15.6 38.6 77.9 28.8 28.5 14.9 9.6 19.1 14.8 28.0 80.0 18.7 15.3 40.6 10.8 30.0 17.5 22.2 27.1 0.0 9.1 14.3 30.5 25.5 11.1 14.8 14.9 15.1 10.6 48.7 15.0 0.0 10.3 40.7 32.9 41.5 6.8 14.7 13.7 45.0 9.2 19.5 19.1 0.0 13.1 20.6 23.1 1.3 13.9 35.1 13.1 22.6 15.1 33.0 20.7 62.9 MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 139.2;Intestinal goblet cells: 79.2;Paneth cells: 98.9;Proximal enterocytes: 133.2;Undifferentiated cells: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 17.0;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA030351: AB_10602185, HPA072906: " "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-2)" "unprognostic (5.81e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (2.88e-2)" "unprognostic (1.22e-1)" "unprognostic (5.83e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (9.12e-2)" 3.6 12.3 3.5 2.9 3.6 0.1 4.1 3.2 4.0 11.0 7.3 22.2 20.3 9.5 6.9 4.3 8.4 12.9 3.2 3.1 3.9 6.9 1.4 3.8 0.7 5.1 4.3 15.2 2.1 5.1 5.3 4.2 3.9 4.7 26.7 1.0 2.2 7.7 1.0 9.4 23.4 13.8 4.5 1.8 3.9 4.9 3.8 0.7 1.6 2.7 0.9 6.9 6.9 4.4 3.1 7.3 3.1 2.6 8.6 10.1 6.6 3.1 10.0 4.0 4.9 0.2 12.9 0.0 6.7 10.6 4.9 4.3 0.3 5.2 2.4 0.2 0.1 0.0 2.3 0.9 2.2 0.0 0.2 6.3 1.7 4.1 6.8 17.0 4.8 0.1 0.2 0.3 7.8 9.9 0.0 0.1 0.7 20.5 2.9 0.0 1.0 0.1 5.8 0.9 0.2 0.2 1.7 2.9 1.1 2.0 3.0 0.0 3.3 4.5 5.4 4.0 2.7 0.6 1.5 0.0 3.9 0.0 0.5 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 3.5 3.6 3.2 4.0 3.1 3.9 5.1 4.3 3.9 4.5 3.8 4.4 2.2 0.0 0.6 2.6 0.5 4.1 3.8 8.9 5.2 0.0 3.0 4.1 6.4 5.7 3.6 14.7 0.0 14.1 0.4 139.2 1.9 15.0 0.6 1.7 3.1 4.5 15.7 0.0 4.0 17.0 10.7 7.0 19.4 2.2 0.0 3.0 3.9 1.5 4.8 0.0 4.9 79.2 0.0 11.3 6.1 0.3 5.6 15.7 1.8 1.0 43.8 0.0 0.0 0.0 3.6 45.1 98.9 12.0 0.3 4.9 133.2 18.5 4.5 0.0 6.6 0.5 7.3 0.4 0.6 3.4 6.5 28.5 0.9 6.4 56.5 4.1 MXRA8 DKFZp586E2023 ENSG00000162576 "Matrix remodeling associated 8" Q9BRK3 1 1352689-1361777 "Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 149.5;Extravillous trophoblasts: 259.9;Fibroblasts: 183.3;Leydig cells: 176.1;Peritubular cells: 183.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "naive CD8 T-cell: 6.4" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 46.0;BJ: 143.6;BJ hTERT+: 66.9;fHDF/TERT166: 71.9;HSkMC: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053958, HPA055780" Uncertain Approved Nucleoli NA NA 760000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli "HPA053958: AB_2682322, HPA055780: AB_2682918" "unprognostic (1.39e-1)" "unprognostic (2.85e-1)" "unprognostic (7.31e-3)" "unprognostic (1.26e-2)" "unprognostic (1.94e-3)" "unprognostic (2.61e-1)" "unprognostic (6.75e-2)" "unprognostic (2.03e-1)" "unprognostic (4.22e-2)" "unprognostic (5.38e-2)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.43e-6)" "prognostic unfavorable (9.93e-4)" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.87e-4)" 103.6 11.7 2.9 8.2 2.5 0.6 70.0 1.1 2.9 100.4 1.7 58.2 6.3 117.2 2.6 17.6 57.4 19.4 42.8 4.0 2.4 26.4 7.4 53.9 2.5 5.9 4.5 81.9 8.7 1.1 21.7 11.6 2.6 39.0 1.7 0.8 32.4 11.4 16.6 41.6 29.5 6.4 2.3 26.4 28.9 14.7 3.2 0.6 46.6 5.0 0.8 52.8 59.3 3.0 4.1 0.8 1.2 1.0 16.5 46.0 42.3 143.6 66.9 16.6 19.9 8.0 3.3 1.7 0.6 71.9 0.1 3.0 1.0 0.0 3.2 3.2 1.3 1.2 3.1 12.8 43.4 0.2 1.6 54.8 0.0 6.2 0.0 32.4 0.0 0.9 17.3 1.4 21.5 0.4 0.4 0.5 14.0 0.3 4.7 0.6 0.3 0.4 0.0 0.7 3.2 8.9 0.5 1.4 0.1 10.4 11.1 0.7 1.3 0.7 23.1 21.8 0.6 3.3 0.3 0.2 5.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 6.4 0.0 0.0 0.0 0.0 0.0 0.2 2.9 2.5 1.1 2.9 4.0 2.4 5.9 4.5 2.6 2.3 3.2 3.0 22.2 3.2 0.0 7.5 0.5 10.7 1.1 0.7 2.2 0.7 7.0 47.9 3.5 0.0 0.0 9.2 0.0 9.5 1.1 0.0 0.0 5.7 1.7 4.3 149.5 5.1 0.0 0.0 0.3 0.0 259.9 183.3 2.6 3.7 0.0 0.5 6.4 0.1 9.3 0.0 0.4 0.0 0.0 0.0 19.7 11.4 176.1 1.7 10.6 6.5 0.7 50.7 0.0 0.0 0.1 1.1 0.0 183.6 1.4 0.6 0.0 1.4 0.0 1.5 13.1 65.8 74.7 0.7 5.4 1.3 10.5 29.4 2.2 0.8 0.0 0.3 MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 207.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 52: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" 179.4 25.7 21.5 66.5 20.2 196.3 82.4 3.1 21.6 97.4 24.6 155.6 48.9 248.6 22.2 76.8 146.5 124.6 92.3 16.7 22.2 19.8 46.4 110.7 37.2 16.9 24.7 73.4 101.1 31.1 17.9 89.6 13.7 75.0 39.9 3.6 48.8 100.9 36.7 45.2 63.8 180.9 6.4 42.5 79.5 28.4 17.3 37.1 57.8 21.1 15.2 104.6 64.8 18.8 28.8 231.6 29.2 23.3 96.2 66.0 45.3 145.9 105.9 57.0 58.7 94.4 84.1 2.6 53.7 187.4 61.6 56.4 14.6 56.7 48.5 34.9 34.2 38.0 35.8 75.6 219.2 78.4 131.3 72.3 12.7 73.4 10.5 93.4 52.0 14.9 41.5 68.7 36.4 32.0 21.4 60.9 27.9 104.3 65.3 82.1 31.0 13.3 63.8 3.0 0.4 43.8 1.2 44.6 14.1 58.4 44.4 66.8 105.5 125.8 44.5 17.0 66.2 44.7 29.9 0.6 78.4 37.1 2.1 74.3 48.1 165.5 20.9 27.1 19.6 5.4 13.4 15.2 59.5 7.1 12.5 11.0 207.4 17.8 23.5 22.3 5.4 20.0 21.5 20.2 3.1 21.6 16.7 22.2 16.9 24.7 13.7 6.4 17.3 18.8 125.9 163.5 59.1 2.9 138.9 103.0 173.3 73.1 96.8 4.1 141.0 105.8 67.1 97.2 91.5 20.2 4.2 46.2 143.3 43.8 0.0 106.6 2.7 97.0 164.1 117.2 202.4 35.7 9.1 51.8 243.9 279.7 83.1 195.5 347.6 27.0 182.8 18.5 73.5 10.1 8.3 203.9 24.4 120.4 217.2 2.2 90.1 180.3 60.5 11.2 68.0 4.0 19.6 7.1 13.9 71.4 54.7 116.6 189.9 56.6 2.7 0.5 57.0 1.4 151.2 340.1 199.0 35.9 14.5 19.7 59.8 49.5 221.5 20.5 93.8 75.0 MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8630761 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.9;Excitatory neurons: 221.3;Inhibitory neurons: 151.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017180, HPA047541, HPA057198" Enhanced Supported "Actin filaments,Mitochondria,Cytosol" NA NA 28000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: AB_2680081, HPA057198: AB_2683364" "unprognostic (4.67e-2)" "unprognostic (9.64e-3)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (2.40e-1)" "unprognostic (2.33e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-3)" "unprognostic (1.69e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.02e-2)" "unprognostic (2.73e-1)" "unprognostic (5.58e-2)" "prognostic unfavorable (6.42e-4)" 27.3 16.9 12.6 6.1 18.9 13.4 14.7 7.0 29.0 19.6 12.6 12.2 2.3 27.8 16.8 6.6 25.2 26.1 38.9 17.9 8.0 32.5 18.9 66.9 6.5 9.6 7.3 25.9 9.8 13.8 17.7 53.4 9.6 17.7 3.8 22.5 6.6 26.6 4.9 7.9 5.8 22.1 0.5 4.6 9.5 7.4 11.0 5.8 13.6 8.2 4.0 10.5 10.3 13.2 54.1 35.1 216.3 72.7 27.7 33.1 97.1 44.2 39.7 52.2 55.8 94.5 8.0 0.5 28.6 43.9 28.4 5.2 108.7 53.0 58.1 1.2 88.3 62.3 21.7 83.0 64.7 5.4 4.2 47.3 18.9 67.7 26.1 32.1 85.3 70.9 88.1 0.2 32.9 21.6 67.2 1.7 102.1 3.6 7.7 105.9 64.2 0.2 59.1 22.3 17.7 96.8 69.2 3.4 68.1 165.0 18.3 3.6 2.8 48.7 35.6 0.3 38.5 8.3 10.8 13.4 0.3 5.0 111.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 12.6 18.9 7.0 29.0 17.9 8.0 9.6 7.3 9.6 0.5 11.0 13.2 43.0 22.4 14.1 43.1 1.1 4.7 9.5 11.2 9.6 37.1 18.7 16.4 33.5 12.8 11.5 101.2 50.1 171.9 1.0 0.8 17.6 13.7 49.1 28.1 37.6 30.6 2.4 43.5 221.3 1.7 88.6 58.0 3.1 28.5 1.3 41.6 55.6 15.3 15.8 35.3 151.1 1.9 6.1 2.7 3.7 28.6 3.7 1.3 1.8 15.9 0.7 25.9 2.1 96.5 15.5 1.9 0.7 39.9 0.6 7.6 0.0 14.0 21.7 39.4 0.0 12.4 23.6 15.6 27.8 9.5 4.0 76.5 2.0 28.0 2.2 4.4 MYOZ3 "CS-3, CS3, FATZ-3, FRP3" ENSG00000164591 "Myozenin 3" Q8TDC0 5 150660882-150679368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "skeletal muscle: 234.2;tongue: 198.4" "Cell type enriched" "Detected in some" 6 "Peritubular cells: 44.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.3;NTERA-2: 9.2;REH: 14.8;SuSa: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA039166 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 37: Myocytes - Muscle contraction" "HPA039166: AB_10671871" "unprognostic (2.74e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-3)" "unprognostic (1.41e-2)" "unprognostic (1.26e-1)" "unprognostic (3.46e-2)" "unprognostic (2.59e-2)" "unprognostic (8.77e-2)" "unprognostic (9.19e-4)" "unprognostic (6.99e-2)" "unprognostic (5.19e-2)" "unprognostic (7.21e-3)" "unprognostic (7.31e-9)" "unprognostic (2.19e-2)" "unprognostic (2.79e-1)" "unprognostic (8.46e-2)" "unprognostic (4.20e-2)" 0.4 0.5 1.9 0.1 1.5 1.1 0.6 1.3 0.8 1.7 0.1 0.3 0.3 1.5 1.4 5.4 0.8 1.4 5.3 1.4 2.6 0.6 0.1 0.8 0.1 8.0 2.6 0.9 0.2 0.0 1.3 0.1 3.0 4.2 0.2 0.2 3.3 1.0 234.2 0.2 0.7 0.8 5.6 0.2 0.5 3.8 2.7 0.4 0.7 198.4 0.0 0.7 0.5 2.8 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.5 0.7 0.0 0.0 0.1 0.0 0.7 1.4 9.2 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 2.6 0.0 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 1.5 1.3 0.8 1.4 2.6 8.0 2.6 3.0 5.6 2.7 2.8 3.5 0.0 0.0 1.0 0.1 0.4 0.4 0.5 0.6 1.1 1.7 1.5 2.9 0.0 0.1 0.0 0.0 0.6 0.9 0.3 0.0 0.0 0.3 0.5 0.7 2.5 0.0 0.0 0.9 0.2 0.3 1.8 0.0 1.4 0.0 4.3 2.9 0.0 0.2 0.0 3.0 0.3 2.0 0.3 1.1 1.2 3.1 0.7 0.0 1.0 0.1 0.5 1.0 0.0 0.2 0.0 0.1 44.4 0.0 0.4 0.5 0.0 0.0 0.0 0.0 7.0 0.8 0.4 1.5 0.0 0.4 0.7 0.5 0.4 0.5 0.1 MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 588.9" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 481.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 137.3;hTERT-HME1: 24.0;HUVEC TERT2: 28.3;OE19: 47.5;RT4: 25.1;TIME: 33.1" HPA039827 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" 65.3 54.7 2.0 2.6 2.4 4.0 22.3 6.3 1.8 17.3 1.3 18.1 16.8 29.4 1.8 41.4 4.7 4.8 588.9 1.8 2.5 5.7 2.4 31.8 6.0 6.7 2.8 5.1 35.1 0.6 1.7 56.6 7.7 19.8 11.8 1.3 18.3 38.2 11.6 9.6 15.4 17.2 1.6 12.4 23.4 2.5 3.5 1.4 3.7 15.5 8.6 84.1 26.9 1.7 6.0 1.7 0.0 10.5 2.3 0.1 3.2 0.9 8.6 1.4 1.7 7.3 4.1 0.1 0.7 0.0 8.9 2.6 0.0 4.4 1.7 0.0 0.2 137.3 1.7 0.1 0.4 0.0 0.1 0.0 3.1 0.3 24.0 0.1 28.3 0.2 1.9 0.0 0.7 2.3 0.0 0.1 0.1 47.5 2.4 0.0 11.4 0.3 0.0 25.1 0.0 4.1 0.6 5.9 0.0 1.2 7.9 0.1 33.1 0.1 2.6 0.4 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.0 3.4 2.0 0.0 0.5 0.0 0.8 0.0 0.2 2.4 2.0 2.4 6.3 1.8 1.8 2.5 6.7 2.8 7.7 1.6 3.5 1.7 22.9 9.6 0.6 0.0 0.3 0.0 10.2 0.0 0.0 0.3 3.0 1.0 481.4 5.7 0.6 25.8 0.0 4.4 0.0 26.9 7.9 32.5 0.1 1.1 3.0 15.1 1.8 1.3 0.0 18.9 2.4 9.8 7.1 3.5 0.0 65.1 4.6 0.2 1.4 0.0 0.0 7.9 0.0 7.9 0.0 0.7 4.7 8.7 0.0 0.0 3.4 0.6 0.0 0.0 0.0 21.5 24.9 17.0 0.0 11.0 18.1 0.3 0.7 0.2 0.0 0.2 8.1 0.0 1.6 0.0 0.0 1.2 0.2 13.2 6.6 22.4 NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 142.2;Kupffer cells: 115.8;Langerhans cells: 109.9;Proximal enterocytes: 167.7" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 672.4;non-classical monocyte: 583.3" "Lineage enriched" "Detected in all" 5 "monocytes: 672.4" "Cell line enhanced" "Detected in many" "U-2197: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" 19.0 14.6 9.2 30.0 10.0 18.5 37.4 10.9 10.8 23.0 14.1 61.8 30.9 12.9 9.1 28.4 16.4 15.7 19.9 9.5 13.3 40.6 68.4 23.0 48.4 11.2 11.1 8.2 7.6 11.7 7.7 19.4 11.7 70.9 69.9 32.7 31.5 11.4 8.6 22.8 60.7 15.4 9.5 63.8 18.5 3.4 13.2 16.3 15.9 13.0 27.9 20.0 18.4 14.5 11.9 26.6 1.1 0.7 62.4 62.8 1.1 17.5 11.6 11.8 4.0 9.3 41.1 1.0 8.9 43.5 0.4 23.1 34.8 13.4 7.1 17.0 1.3 8.4 19.4 22.6 14.3 31.4 29.6 16.0 10.0 10.3 3.5 18.4 19.1 18.7 9.6 35.9 10.6 43.5 20.2 20.5 13.5 53.4 10.5 13.5 0.4 55.6 12.4 6.7 15.9 2.3 18.1 56.2 5.4 1.8 63.3 54.1 28.8 0.7 1.5 78.6 0.8 8.8 3.8 5.9 14.8 44.5 7.4 48.6 270.1 110.3 62.0 672.4 67.5 58.8 78.4 61.8 143.2 40.4 65.2 54.5 90.3 35.5 583.3 53.2 114.6 233.7 9.2 10.0 10.9 10.8 9.5 13.3 11.2 11.1 11.7 9.5 13.2 14.5 10.6 0.0 7.3 7.2 31.2 11.3 18.8 5.7 4.0 11.5 31.3 14.2 4.4 25.8 10.9 5.5 18.8 24.6 19.5 142.2 13.7 5.7 0.5 12.1 18.1 14.6 48.0 10.8 17.7 8.4 19.2 28.2 3.1 11.9 15.2 3.5 18.5 37.2 39.7 11.8 27.4 45.4 8.2 115.8 109.9 0.0 10.5 80.3 17.8 7.5 77.8 7.7 16.5 5.0 4.8 4.1 46.7 7.5 16.8 55.4 167.7 12.4 27.7 86.9 0.0 31.8 16.7 1.1 0.9 15.9 18.9 13.3 34.8 9.1 24.4 14.0 NAALAD2 "GCPIII, NAALADASE2" ENSG00000077616 "N-acetylated alpha-linked acidic dipeptidase 2" Q9Y3Q0 11 90131515-90192894 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Dipeptidase, Hydrolase, Metalloprotease, Multifunctional enzyme, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.9;testis: 13.9" "Group enriched" "Detected in many" 4 "Early spermatids: 39.7;Excitatory neurons: 109.3;Horizontal cells: 70.7;Inhibitory neurons: 110.2;Oligodendrocyte precursor cells: 153.8;Oligodendrocytes: 83.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 19.2;SH-SY5Y: 6.1;SuSa: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA060820, HPA065419" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA060820: AB_2684373, HPA065419: AB_2685487" "unprognostic (1.68e-1)" "unprognostic (2.66e-3)" "unprognostic (1.49e-1)" "unprognostic (4.52e-3)" "unprognostic (4.73e-3)" "unprognostic (2.97e-1)" "unprognostic (3.82e-3)" "unprognostic (1.77e-2)" "unprognostic (2.44e-1)" "unprognostic (2.30e-1)" "unprognostic (3.30e-2)" "unprognostic (8.00e-2)" "unprognostic (9.97e-4)" "unprognostic (1.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.63e-2)" "unprognostic (2.93e-1)" 3.8 10.0 2.3 0.4 3.3 0.1 3.3 1.5 5.3 10.3 0.0 1.9 0.2 4.1 1.9 0.8 3.4 1.2 2.1 2.4 2.8 1.5 0.9 2.1 0.4 3.6 3.5 7.4 0.7 0.1 19.9 3.5 3.4 3.2 0.6 3.5 1.1 1.2 1.1 0.7 1.3 1.1 2.0 2.6 1.2 13.9 3.0 0.1 1.4 0.7 0.1 2.2 4.0 4.2 0.1 0.2 1.8 0.1 0.5 0.1 2.2 0.1 0.1 0.1 0.0 19.2 0.7 0.3 0.2 0.0 0.3 0.3 1.3 0.0 0.0 0.0 0.3 1.9 0.4 1.7 0.2 0.1 0.1 1.9 0.0 0.0 0.0 0.5 0.4 0.2 0.1 0.0 0.0 0.0 0.3 0.3 1.8 0.5 0.2 0.3 0.0 0.2 0.0 0.0 0.2 6.1 0.0 0.2 0.0 4.3 0.2 0.4 2.4 0.1 1.4 0.3 0.3 1.0 0.3 0.3 0.6 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.3 3.3 1.5 5.3 2.4 2.8 3.6 3.5 3.4 2.0 3.0 4.2 2.6 0.0 0.0 3.3 0.1 0.3 0.1 0.0 0.0 17.3 0.0 0.0 2.4 1.5 0.6 0.0 0.0 1.2 0.1 0.0 0.0 0.1 39.7 0.8 13.7 1.2 0.0 0.0 109.3 0.0 0.6 7.5 1.1 0.6 0.0 1.7 0.7 0.2 0.3 70.7 110.2 0.0 0.0 7.2 0.4 17.7 11.1 0.5 0.0 12.2 0.0 8.4 0.0 153.8 83.7 0.0 0.0 14.7 0.4 0.4 0.0 0.1 0.0 2.4 0.0 6.4 4.6 0.6 11.3 0.4 0.0 0.8 0.2 19.4 0.2 0.1 NAALADL2 ENSG00000177694 "N-acetylated alpha-linked acidic dipeptidase like 2" Q58DX5 3 174438573-175810548 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 311.5;Inhibitory neurons: 135.1;Microglial cells: 155.5;Oligodendrocyte precursor cells: 468.0;Oligodendrocytes: 532.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 14.5;BJ hTERT+: 5.4;fHDF/TERT166: 6.4;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA012413, HPA017425, CAB025586" Approved Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "CAB025586: , HPA012413: AB_1854274, HPA017425: AB_1854275" "unprognostic (7.28e-3)" "unprognostic (1.10e-1)" "unprognostic (6.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.56e-1)" "unprognostic (2.56e-1)" "unprognostic (2.29e-4)" "unprognostic (3.44e-3)" "unprognostic (5.70e-2)" "unprognostic (7.42e-2)" "unprognostic (7.85e-3)" "unprognostic (9.49e-2)" "unprognostic (3.66e-6)" "unprognostic (7.11e-2)" "unprognostic (1.48e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" 2.4 1.1 1.1 1.0 2.3 0.2 5.8 1.2 1.4 6.3 1.1 3.0 1.7 3.7 5.5 1.5 3.8 4.2 2.6 1.4 0.6 3.3 2.9 2.0 0.5 2.2 1.3 3.9 2.2 10.2 0.5 1.2 1.8 4.9 2.4 1.6 5.8 3.7 1.0 0.8 1.6 3.5 1.4 1.9 2.7 0.9 1.5 1.2 2.3 1.7 0.5 3.8 1.2 3.3 0.0 0.0 0.3 0.0 4.4 14.5 0.1 3.1 5.4 0.7 0.9 0.2 1.7 0.0 0.6 6.4 0.2 0.1 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 4.1 0.8 0.1 0.0 3.8 0.5 0.0 0.0 0.1 3.1 0.6 0.2 0.0 0.0 2.2 0.0 0.0 0.2 0.1 2.2 0.3 0.1 0.1 0.3 0.3 1.2 0.3 4.0 0.2 0.7 2.9 0.1 0.1 0.6 0.0 0.0 0.0 1.9 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.1 2.3 1.2 1.4 1.4 0.6 2.2 1.3 1.8 1.4 1.5 3.3 5.1 0.0 11.5 311.5 0.1 2.3 8.9 2.7 1.2 7.7 35.1 13.7 3.0 12.8 9.1 12.9 12.5 19.6 0.3 11.1 7.9 10.1 74.9 23.7 8.7 2.8 9.0 2.7 113.4 2.5 1.4 15.0 23.9 30.2 4.5 3.4 2.9 4.5 1.8 0.0 135.1 2.6 10.2 0.3 3.0 39.6 15.2 1.1 3.6 155.5 0.0 6.7 0.0 468.0 532.9 3.6 4.4 12.0 0.0 13.6 13.2 2.4 21.9 6.2 0.0 23.4 4.9 3.2 2.8 5.3 1.8 12.3 0.8 5.7 16.4 16.0 NAV3 "KIAA0938, POMFIL1" ENSG00000067798 "Neuron navigator 3" Q8IVL0 12 77324641-78213010 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3;ovary: 18.3" "Group enriched" "Detected in many" 6 "Astrocytes: 882.1;Excitatory neurons: 1473.6;Inhibitory neurons: 753.8;Microglial cells: 534.0;Oligodendrocyte precursor cells: 786.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 9.7;basal ganglia: 15.0;cerebral cortex: 17.3;hippocampal formation: 13.6;white matter: 10.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.0;THP-1: 41.8;U-138 MG: 30.8;WM-115: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032111, HPA061392" Approved Approved "Nuclear membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane" Cytosol "HPA032111: AB_10603881, HPA061392: " "unprognostic (3.51e-1)" "unprognostic (6.72e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-1)" "unprognostic (3.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.06e-2)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (5.68e-7)" "unprognostic (6.86e-3)" "unprognostic (1.23e-1)" "unprognostic (1.58e-2)" "unprognostic (2.29e-3)" 3.8 4.8 9.7 1.0 15.0 0.5 4.0 0.9 17.3 1.2 0.0 1.7 0.3 2.0 2.9 1.9 2.2 5.1 1.9 13.6 0.0 0.4 1.0 3.3 0.6 0.7 0.4 18.3 0.5 0.4 3.1 2.2 0.0 2.1 0.8 5.2 0.9 2.5 1.3 2.6 0.6 2.5 1.4 8.0 0.8 2.8 1.6 1.9 1.2 3.4 0.4 3.3 1.7 10.3 3.5 8.7 0.6 0.2 8.5 18.1 0.3 26.5 20.9 10.7 5.3 1.7 0.6 0.2 1.9 22.0 7.2 2.5 7.8 4.0 19.3 0.1 0.2 0.2 3.9 0.2 6.7 0.1 0.2 6.2 0.2 47.0 11.1 9.3 16.4 0.1 0.0 0.1 26.2 0.5 0.2 12.0 2.7 0.3 2.1 1.0 2.1 0.0 1.7 0.1 0.6 0.0 1.6 0.3 3.5 0.8 0.1 41.8 14.1 30.8 8.1 12.0 18.2 1.2 0.0 0.7 8.8 0.5 38.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 9.7 15.0 0.9 17.3 13.6 0.0 0.7 0.4 0.0 1.4 1.6 10.3 11.1 19.2 10.0 882.1 0.0 3.6 8.4 0.2 0.0 5.0 3.8 3.8 3.4 0.0 7.5 0.0 0.0 0.1 0.0 0.2 0.0 4.2 10.4 4.2 8.2 5.6 16.4 0.0 1473.6 1.6 0.1 18.7 0.5 10.3 11.4 0.8 3.9 0.0 7.3 50.5 753.8 0.0 0.0 0.0 3.7 4.7 23.9 1.4 12.4 534.0 0.1 18.3 0.0 786.1 144.1 19.2 0.0 7.5 1.2 18.0 0.0 0.3 8.7 2.0 0.0 28.8 5.3 0.3 0.8 0.2 1.4 0.3 1.3 73.7 0.0 2.9 NCALD ENSG00000104490 "Neurocalcin delta" P61601 8 101686542-102124907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 100.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.6;Inhibitory neurons: 460.2;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 87.3" "Group enriched" "Detected in many" 13 "NK-cells: 87.3;T-cells: 42.2" "Cell line enhanced" "Detected in many" "AF22: 136.4;HDLM-2: 159.9;U-266/70: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043245: AB_2678385" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (4.85e-2)" "unprognostic (4.97e-2)" "unprognostic (5.48e-3)" "unprognostic (2.60e-3)" "unprognostic (1.25e-1)" "unprognostic (5.63e-3)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "prognostic favorable (5.30e-4)" "unprognostic (2.79e-1)" "unprognostic (6.24e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-1)" "unprognostic (7.87e-2)" "unprognostic (1.00e-2)" 21.4 7.3 30.3 9.4 43.4 1.8 44.0 0.0 62.5 13.5 0.0 22.3 6.0 7.6 4.4 12.6 39.6 12.6 12.1 52.4 11.3 14.9 15.1 19.7 13.6 3.6 13.3 37.5 10.0 1.9 13.7 10.0 15.3 12.3 8.8 15.9 100.6 14.9 15.4 18.0 10.2 11.0 1.2 8.3 11.2 7.3 29.4 5.5 5.2 11.6 11.1 11.1 4.0 21.6 6.9 9.8 136.4 0.5 1.1 22.3 0.0 2.3 0.3 0.1 0.0 0.1 0.1 9.0 3.0 10.4 0.6 0.0 1.0 0.0 0.0 159.9 1.0 0.7 0.0 0.0 0.0 6.1 0.9 4.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 19.3 0.8 0.2 1.2 2.4 1.5 0.0 0.0 3.7 0.0 0.4 22.0 0.3 0.6 13.4 0.0 3.1 5.7 22.5 0.9 4.8 0.2 1.6 0.3 0.2 0.4 39.3 5.6 0.1 0.3 0.1 2.2 0.4 0.3 0.3 42.2 0.2 37.1 0.9 16.0 24.8 5.0 0.6 3.9 20.6 1.3 87.3 0.3 0.4 17.5 13.6 30.3 43.4 0.0 62.5 52.4 11.3 3.6 13.3 15.3 1.2 29.4 21.6 17.3 0.0 2.6 11.8 0.5 4.2 0.5 1.0 0.0 14.6 88.6 74.4 7.5 14.3 3.2 0.0 25.0 3.2 28.9 1.7 7.9 9.6 12.8 32.2 5.0 11.3 21.0 4.0 251.6 1.2 13.0 39.8 4.1 23.8 2.5 20.5 14.6 15.0 1.9 13.5 460.2 4.3 61.1 2.6 6.9 6.6 2.8 2.8 103.2 75.9 0.8 46.6 64.9 281.0 26.5 3.5 0.5 1.5 7.1 1.3 0.0 19.5 26.0 4.7 26.3 91.0 24.5 1.5 1.8 3.0 3.1 3.0 17.4 19.4 0.4 1.1 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 NDN "HsT16328, PWCR" ENSG00000182636 "Necdin, MAGE family member" Q99608 15 23685400-23687305 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 236.4;Peritubular cells: 207.6;Theca cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.5" "Cell line enhanced" "Detected in many" "AF22: 55.0;ASC diff: 52.9;HSkMC: 71.3;NTERA-2: 44.0;SuSa: 57.4;U-2 OS: 80.4;U-266/70: 51.7;U-266/84: 51.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074457 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "HPA074457: AB_2686691" "unprognostic (3.49e-1)" "unprognostic (1.65e-1)" "unprognostic (4.20e-1)" "unprognostic (2.19e-2)" "unprognostic (2.71e-1)" "unprognostic (9.04e-2)" "unprognostic (6.79e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (4.05e-2)" "prognostic unfavorable (4.52e-4)" "unprognostic (1.89e-2)" "unprognostic (8.10e-2)" "unprognostic (1.96e-1)" "unprognostic (6.81e-2)" 46.8 49.4 43.3 11.1 40.5 1.2 35.1 26.0 39.7 70.5 30.4 35.9 11.1 63.7 24.0 16.8 47.2 23.8 34.6 36.7 89.6 13.0 4.5 19.6 10.9 36.0 41.3 69.8 11.8 8.7 56.3 32.6 46.2 27.3 10.7 20.8 12.7 39.3 14.7 11.9 20.8 33.5 36.7 19.1 20.3 18.5 69.6 6.8 17.4 22.4 6.6 31.4 40.4 32.3 0.1 0.0 55.0 0.0 52.9 20.1 0.1 35.4 0.0 0.8 9.6 0.0 0.0 0.0 0.1 10.6 8.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 31.8 71.3 0.0 10.2 0.0 0.0 0.0 21.7 1.2 0.0 18.0 0.0 27.6 0.1 44.0 0.0 0.0 0.0 0.0 0.1 3.8 0.0 0.1 0.4 0.0 0.4 0.0 57.4 9.4 0.0 0.0 2.6 80.4 0.0 0.1 51.7 51.7 0.0 5.5 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.2 1.5 0.0 0.0 43.3 40.5 26.0 39.7 36.7 89.6 36.0 41.3 46.2 36.7 69.6 32.3 24.1 25.6 11.0 6.8 0.3 13.0 13.8 0.3 27.9 66.0 2.3 19.8 36.8 15.7 1.4 12.9 20.9 1.9 2.9 18.5 23.5 17.9 2.5 1.4 60.8 18.7 6.7 4.2 7.8 10.7 1.4 103.1 4.1 1.1 0.0 83.9 38.9 0.2 7.3 50.5 21.8 4.3 0.0 7.6 13.3 8.6 236.4 2.8 39.2 9.4 0.7 88.7 0.0 9.5 16.4 4.5 2.6 207.6 0.0 6.9 8.1 1.1 4.1 51.0 98.6 91.4 94.0 28.5 21.8 13.4 8.2 2.5 1.4 121.8 7.1 4.1 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NFIX NF1A ENSG00000008441 "Nuclear factor I X" Q14938 19 12995475-13098796 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA replication, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 410.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 145.2;Oligodendrocytes: 140.9;Skeletal myocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 149.5;fHDF/TERT166: 211.3;U-138 MG: 191.5;U-2197: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007533 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA007533: AB_2667855" "unprognostic (3.32e-1)" "unprognostic (1.37e-2)" "unprognostic (2.84e-1)" "unprognostic (2.20e-1)" "unprognostic (2.29e-1)" "unprognostic (8.12e-2)" "prognostic favorable (4.66e-4)" "prognostic favorable (2.35e-4)" "unprognostic (1.26e-1)" "unprognostic (2.01e-2)" "unprognostic (3.25e-1)" "unprognostic (2.63e-2)" "unprognostic (1.08e-2)" "unprognostic (3.46e-2)" "unprognostic (2.92e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-2)" 76.4 14.9 30.4 19.7 80.2 14.9 48.0 99.8 97.7 67.2 4.0 60.4 20.9 88.5 10.9 72.4 69.5 53.9 60.9 54.0 15.0 8.9 20.3 50.0 6.2 50.9 45.1 73.8 23.8 13.2 18.9 11.8 39.4 85.0 19.7 11.7 150.4 60.0 410.3 99.2 24.3 67.8 45.6 11.3 37.3 16.0 46.9 11.6 31.0 138.2 6.2 45.0 52.7 105.2 39.2 16.2 1.0 119.9 111.7 149.5 1.3 48.1 68.6 45.7 31.8 1.3 3.3 0.6 13.4 211.3 31.4 17.5 12.8 37.4 20.1 25.8 19.7 20.2 7.6 17.2 53.8 8.5 10.3 99.0 10.9 44.1 24.6 80.3 12.4 8.6 6.7 6.2 29.3 12.1 14.9 5.7 0.5 8.6 132.3 43.5 22.2 23.1 0.4 8.5 17.9 47.6 34.5 0.3 43.0 0.0 22.7 17.3 12.2 191.5 23.5 185.1 68.5 4.5 1.7 0.3 49.9 12.1 62.0 0.1 0.1 0.0 0.5 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 30.4 80.2 99.8 97.7 54.0 15.0 50.9 45.1 39.4 45.6 46.9 105.2 19.5 12.8 59.3 62.7 6.8 58.8 45.5 22.4 134.9 13.3 57.9 74.2 33.2 27.1 15.9 14.7 4.2 0.2 3.7 16.5 1.9 24.3 64.0 12.1 40.1 20.0 12.1 145.2 69.0 12.7 0.3 89.7 32.6 3.0 3.8 4.3 17.9 33.9 1.0 0.0 38.1 25.8 2.0 4.1 15.2 43.1 112.2 5.8 26.6 17.8 1.9 93.7 0.0 52.3 140.9 15.2 12.0 126.0 2.5 60.3 8.4 10.0 19.0 3.0 6.6 174.7 38.3 15.6 13.2 99.4 51.4 0.3 3.8 56.0 29.5 31.8 NIPAL2 "FLJ13955, NPAL2" ENSG00000104361 "NIPA like domain containing 2" Q9H841 8 98189826-98294393 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 124.5;Squamous epithelial cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 45.5;OE19: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071759 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071759: AB_2686443" "unprognostic (5.14e-3)" "unprognostic (6.43e-2)" "unprognostic (8.01e-2)" "unprognostic (2.02e-1)" "unprognostic (4.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.72e-1)" "unprognostic (9.45e-2)" "unprognostic (1.90e-2)" "unprognostic (3.67e-1)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.18e-3)" "unprognostic (1.28e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (4.76e-2)" 12.6 12.5 6.1 7.8 6.6 6.4 17.7 4.2 13.5 22.9 5.2 17.8 9.2 14.5 41.0 30.1 12.2 15.4 8.6 7.7 5.1 5.9 7.8 10.3 8.6 3.7 3.5 27.5 16.8 11.7 21.9 8.5 3.8 22.9 24.1 11.7 20.6 15.9 2.3 53.2 11.7 7.8 5.0 8.1 19.7 4.9 4.3 3.4 7.2 2.6 13.0 13.2 21.8 8.8 7.9 3.1 1.0 0.1 45.5 27.5 0.2 13.9 17.6 2.5 3.4 0.0 22.7 14.7 15.7 19.5 3.7 9.2 0.7 8.3 1.9 1.3 2.8 5.4 2.1 1.1 5.8 5.7 5.5 28.4 21.6 2.6 7.6 1.4 3.2 0.1 0.0 29.1 10.2 10.9 0.2 3.1 1.8 38.1 1.1 0.0 0.2 1.7 9.1 17.7 1.5 3.0 10.1 8.6 3.5 1.2 9.2 10.5 9.2 1.9 0.2 7.0 0.1 0.3 0.0 0.1 3.4 18.2 9.5 0.1 2.0 2.9 0.7 1.9 0.0 1.7 0.6 0.6 3.7 2.6 0.0 0.5 0.3 1.7 1.6 1.5 2.0 1.6 6.1 6.6 4.2 13.5 7.7 5.1 3.7 3.5 3.8 5.0 4.3 8.8 6.1 3.2 9.3 3.6 11.0 15.3 8.4 19.2 22.8 16.5 10.4 10.8 5.2 7.2 15.8 3.7 2.1 0.2 3.0 20.6 0.0 8.2 7.3 4.6 21.1 8.0 7.2 11.2 124.5 12.8 1.1 13.2 30.5 5.4 5.7 4.1 8.6 3.6 4.6 21.9 30.5 26.3 6.1 6.8 9.4 4.0 25.7 8.5 3.6 26.2 6.0 9.7 10.3 10.6 3.4 9.4 11.0 23.0 6.6 13.4 8.6 1.2 14.3 2.6 6.6 3.3 6.8 0.8 0.7 57.3 22.9 0.3 3.0 12.4 17.2 22.7 NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144831-71171201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;seminal vesicle: 12.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Inhibitory neurons: 12.7;Oligodendrocyte precursor cells: 92.0;Oligodendrocytes: 43.7;Peritubular cells: 17.3" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.7;NTERA-2: 5.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" 0.5 6.6 10.1 0.8 8.5 1.4 0.4 6.4 11.1 1.9 0.0 1.8 0.2 2.7 6.4 0.6 4.3 1.4 1.1 10.3 10.2 0.3 0.1 0.6 0.4 7.3 7.0 4.4 0.3 0.5 1.0 0.6 4.8 6.0 0.5 1.9 0.6 12.5 0.1 0.7 0.7 1.9 5.5 0.6 0.6 2.6 7.3 0.4 0.4 0.4 0.2 0.7 1.2 9.7 0.0 0.5 6.7 0.2 1.6 0.6 1.2 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.5 0.1 0.0 0.1 0.2 0.0 0.1 0.4 0.9 0.4 0.4 0.0 0.0 0.1 0.4 0.4 0.1 0.2 0.0 0.3 0.1 2.0 0.5 1.5 0.0 0.3 0.5 1.2 5.3 0.0 0.0 0.6 0.2 0.3 0.0 0.8 1.7 2.5 0.2 0.0 0.6 0.8 0.0 0.3 0.1 0.1 0.8 0.2 0.0 1.1 1.1 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 8.5 6.4 11.1 10.3 10.2 7.3 7.0 4.8 5.5 7.3 9.7 0.3 0.0 0.0 19.6 0.0 0.6 0.3 0.2 1.2 2.6 0.3 0.9 0.4 0.0 0.1 0.0 0.0 1.0 0.2 0.2 0.0 0.1 1.3 0.2 1.1 0.5 0.0 0.0 11.3 0.0 0.2 1.3 0.0 0.4 0.0 1.0 0.7 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.8 3.9 2.1 0.2 0.0 2.8 0.1 2.5 0.0 92.0 43.7 0.2 0.1 17.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.6 0.2 0.0 0.1 0.4 0.3 0.2 4.5 0.1 0.3 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Cell type enhanced" "Detected in some" "dendritic cells: 13.7;Hepatic stellate cells: 7.9;NK-cells: 47.4;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Group enriched" "Detected in many" 7 "gdT-cell: 18.1;MAIT T-cell: 4.6;memory CD8 T-cell: 8.8;naive CD8 T-cell: 5.2;NK-cell: 10.9" "Group enriched" "Detected in many" 19 "NK-cells: 10.9;T-cells: 18.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 63: NK-cells & T-cells - Immune response" "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" 5.2 1.3 0.1 0.5 0.1 2.6 1.5 1.1 0.3 0.7 0.0 1.1 2.8 0.9 2.3 1.6 1.4 0.7 0.7 0.1 0.0 1.0 0.8 3.1 0.5 0.0 0.0 0.3 4.2 0.3 0.2 1.3 0.0 1.3 0.8 8.2 1.2 2.1 0.2 0.4 3.7 0.9 0.0 3.6 0.8 1.5 0.0 0.1 0.8 0.0 0.2 1.3 0.6 0.0 0.0 0.2 0.3 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.7 0.1 0.0 18.1 0.0 4.6 0.1 1.3 8.8 0.1 0.0 0.1 5.2 0.7 10.9 0.1 0.4 0.6 4.9 0.1 0.1 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 1.3 0.0 0.1 2.5 0.0 0.0 0.0 2.1 0.5 13.7 0.0 0.0 0.0 1.2 0.4 0.2 0.6 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.1 1.3 0.0 7.9 0.0 0.2 1.7 0.7 0.1 0.0 0.9 1.4 0.5 2.1 0.3 0.0 0.0 0.2 2.6 47.4 0.5 0.1 0.1 0.0 7.5 2.4 0.1 0.0 0.1 0.0 17.2 0.0 0.2 0.9 2.2 4.7 0.0 0.4 0.7 6.9 5.2 0.0 0.1 NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB010435: AB_2155784, HPA004248: AB_1078976" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.43e-2)" "unprognostic (2.74e-1)" "unprognostic (4.19e-1)" "unprognostic (1.39e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-2)" "unprognostic (2.15e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.72e-6)" "unprognostic (9.06e-3)" "unprognostic (1.02e-1)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" 35.3 11.8 15.2 22.6 18.1 49.4 25.5 34.0 24.7 19.7 18.2 13.7 19.2 18.8 13.6 25.7 18.8 21.1 24.2 14.9 25.0 19.2 39.8 31.9 25.6 18.1 14.9 21.1 14.7 33.8 16.2 46.9 16.1 19.7 14.5 9.5 16.1 20.0 45.0 20.4 18.0 23.8 15.0 24.5 16.0 11.1 21.6 40.0 25.6 40.1 27.3 18.2 16.0 28.5 30.4 60.6 4.4 0.1 38.2 42.3 5.2 46.5 55.3 39.3 45.1 4.5 39.7 26.8 20.8 68.6 46.0 28.1 0.3 36.6 48.3 15.2 21.0 6.9 77.0 13.5 35.7 28.1 20.6 30.8 46.3 64.7 62.5 49.0 15.0 12.1 10.3 98.8 35.1 10.9 16.7 20.0 11.9 5.1 13.0 6.0 41.4 58.0 11.5 2.1 8.0 6.1 81.3 11.7 19.4 4.9 5.3 39.8 35.8 94.7 18.7 45.7 35.9 20.1 19.7 41.5 49.7 28.5 33.6 67.4 21.3 38.9 18.3 24.2 15.1 15.9 18.6 17.9 28.5 22.3 17.8 17.2 68.4 23.1 23.6 25.9 12.8 17.3 15.2 18.1 34.0 24.7 14.9 25.0 18.1 14.9 16.1 15.0 21.6 28.5 152.3 67.3 69.1 71.2 134.1 58.8 35.9 37.9 79.6 13.1 39.0 55.8 43.4 57.2 41.2 25.8 16.7 48.9 158.3 22.9 17.6 30.8 165.6 8.1 30.1 82.3 28.1 55.9 411.4 33.3 39.5 112.2 23.9 10.4 89.3 7.5 63.5 193.9 53.2 37.0 169.5 4.1 10.2 66.3 99.2 144.1 63.0 97.4 53.4 241.7 87.6 34.6 83.4 240.3 237.5 35.9 17.9 71.5 115.1 46.2 25.3 67.9 37.9 65.0 151.2 181.9 105.0 24.5 40.1 57.4 56.3 36.5 204.5 12.6 12.9 14.3 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRIP2 DKFZP761G1913 ENSG00000053702 "Nuclear receptor interacting protein 2" Q9BQI9 12 2825348-2835544 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Rod photoreceptor cells: 8.8;Sertoli cells: 26.3;Smooth muscle cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039197, HPA039860" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039197: AB_10673416, HPA039860: AB_10794203" "unprognostic (3.28e-3)" "unprognostic (3.83e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (2.10e-2)" "unprognostic (8.11e-2)" "unprognostic (4.26e-3)" "unprognostic (5.66e-2)" "unprognostic (4.42e-3)" "unprognostic (2.89e-1)" "unprognostic (4.39e-2)" "prognostic favorable (8.69e-5)" "unprognostic (7.15e-2)" "unprognostic (2.82e-2)" "unprognostic (7.55e-2)" "unprognostic (5.23e-2)" "unprognostic (1.00e-1)" "unprognostic (8.97e-2)" 5.4 3.9 7.7 3.6 12.4 4.0 5.1 23.4 10.2 7.0 4.8 5.3 2.4 7.4 7.2 2.4 4.8 5.9 5.2 5.8 10.6 12.0 1.6 1.8 4.1 12.4 10.0 8.4 3.0 0.6 2.8 2.6 12.9 4.1 3.0 3.9 3.6 4.9 4.9 2.6 4.7 4.9 8.1 9.1 3.6 2.1 12.0 3.0 5.5 7.5 2.6 4.3 4.7 13.3 0.4 0.9 1.5 0.8 0.0 0.0 1.8 1.1 0.0 0.0 0.0 2.3 1.1 1.2 0.3 0.0 0.3 0.8 0.0 0.0 0.0 0.9 1.3 2.0 2.9 0.2 0.0 2.4 1.4 0.0 0.0 0.0 0.0 2.2 0.0 1.3 1.1 2.7 0.0 1.0 1.5 1.2 1.5 0.9 0.4 0.9 1.6 0.7 0.0 1.5 1.1 1.7 0.8 1.2 0.3 2.7 0.8 0.4 1.2 0.6 0.7 0.9 1.6 0.4 0.1 1.8 1.5 1.1 0.8 3.7 0.3 0.1 0.5 0.2 0.3 0.7 0.4 0.5 0.2 0.6 0.8 0.3 0.1 0.4 0.1 0.3 0.1 0.1 7.7 12.4 23.4 10.2 5.8 10.6 12.4 10.0 12.9 8.1 12.0 13.3 0.6 0.0 1.1 0.0 0.2 0.1 0.5 0.0 0.0 5.0 0.1 0.9 1.3 0.0 0.0 1.8 6.2 0.3 0.3 0.0 0.0 0.0 1.6 0.2 0.9 0.6 0.0 0.0 1.8 0.0 0.0 1.3 0.0 0.3 0.0 0.2 0.4 0.0 0.1 3.3 3.3 0.0 0.0 0.6 0.3 1.8 0.3 0.5 0.0 2.8 0.0 0.6 3.1 0.5 4.9 0.0 0.0 5.3 0.0 0.3 0.0 0.2 0.0 8.8 26.3 0.5 23.1 0.1 0.3 0.1 0.1 0.0 1.1 0.4 0.0 0.1 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NRXN2 ENSG00000110076 "Neurexin 2" "P58401, Q9P2S2" 11 64606174-64723197 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.4;Horizontal cells: 149.7;Inhibitory neurons: 47.8;Late spermatids: 49.7;Muller glia cells: 60.7;Oligodendrocyte precursor cells: 47.3;Peritubular cells: 59.0" "Cancer enhanced" "Detected in many" "glioma: 12.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 47.8;SCLC-21H: 22.8;SH-SY5Y: 10.5;U-2 OS: 26.1;U-87 MG: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 1000000 "Cluster 7: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (3.87e-2)" "unprognostic (1.54e-4)" "unprognostic (2.60e-2)" "unprognostic (1.96e-1)" "unprognostic (8.07e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (5.08e-2)" "unprognostic (3.23e-1)" "unprognostic (5.93e-3)" "unprognostic (3.40e-1)" "unprognostic (9.97e-3)" "unprognostic (2.39e-2)" "unprognostic (6.99e-2)" "unprognostic (4.27e-4)" "unprognostic (5.46e-3)" 3.8 4.7 61.0 2.0 51.6 0.5 2.6 73.6 65.9 27.0 0.0 17.1 1.0 19.0 1.1 0.4 14.6 2.2 3.7 61.9 21.8 5.8 1.0 1.5 1.0 16.0 18.2 15.5 3.0 0.1 4.3 0.7 11.6 4.9 0.6 13.0 1.6 2.9 1.1 0.9 2.7 2.4 4.6 1.5 2.4 15.3 24.8 0.8 4.0 0.3 0.4 5.9 7.4 18.3 0.0 0.0 2.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 2.1 0.0 0.3 0.3 2.5 2.0 0.1 3.3 0.0 0.0 0.3 0.4 6.5 0.0 0.0 0.0 0.0 0.5 1.2 0.0 4.5 0.0 0.0 0.0 0.1 0.0 9.0 3.1 0.0 0.7 0.3 7.6 0.0 0.0 47.8 1.4 1.9 0.0 0.0 22.8 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.3 1.1 26.1 0.5 0.0 0.0 0.0 0.0 18.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 61.0 51.6 73.6 65.9 61.9 21.8 16.0 18.2 11.6 4.6 24.8 18.3 0.5 0.0 0.0 13.1 0.0 0.5 0.1 0.0 0.0 72.4 0.2 0.6 3.2 0.0 0.0 1.8 6.2 0.1 0.6 6.3 3.9 0.0 23.6 0.9 23.5 2.5 6.7 2.1 36.0 2.7 0.2 7.3 0.0 0.6 0.0 0.7 2.9 8.6 0.2 149.7 47.8 1.1 0.0 1.2 0.7 49.7 42.6 1.2 0.0 7.5 0.7 60.7 6.2 47.3 26.0 0.4 2.5 59.0 0.0 0.1 5.1 40.9 0.0 21.7 0.0 27.3 4.0 37.5 15.2 0.0 0.1 0.3 0.7 4.9 0.9 0.0 NRXN3 "C14orf60, KIAA0743" ENSG00000021645 "Neurexin 3" "Q9HDB5, Q9Y4C0" 14 78170373-79868291 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.8;retina: 42.9" "Group enriched" "Detected in many" 10 "Excitatory neurons: 3526.5;Inhibitory neurons: 5083.8;Oligodendrocytes: 2145.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 106.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 9.7;RT4: 24.7;SK-BR-3: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002727 Approved NA NA 710000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA002727: AB_1079468" "unprognostic (7.96e-2)" "unprognostic (5.70e-4)" "unprognostic (8.18e-3)" "unprognostic (2.19e-2)" "unprognostic (2.31e-4)" "unprognostic (9.56e-2)" "unprognostic (2.80e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-2)" "unprognostic (7.91e-2)" "unprognostic (2.40e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.83e-7)" "unprognostic (4.81e-2)" "unprognostic (2.61e-1)" "unprognostic (3.61e-2)" "unprognostic (2.91e-1)" 0.8 5.9 13.4 2.8 17.0 0.1 1.6 106.8 48.3 3.9 0.0 23.0 2.3 5.4 1.7 4.7 5.0 2.5 3.0 23.6 21.3 1.7 0.4 2.6 0.4 8.6 24.2 0.7 3.1 8.8 4.9 1.3 7.2 6.7 4.1 42.9 2.8 11.3 0.3 1.8 8.4 21.1 0.0 5.8 9.3 7.5 4.2 1.0 0.5 0.5 0.4 4.4 2.7 21.5 0.0 0.0 7.6 0.0 0.2 0.3 0.0 3.0 2.2 9.7 7.3 2.6 0.0 0.1 0.0 0.3 0.0 2.8 0.1 0.3 6.8 3.0 6.0 0.0 0.2 0.0 0.7 0.0 0.0 1.8 0.3 4.3 1.4 4.6 2.5 0.0 0.0 0.2 0.1 0.1 0.2 0.2 1.6 0.0 0.0 0.2 0.0 0.0 5.2 24.7 1.3 0.0 0.0 9.3 0.5 3.1 0.0 0.0 0.0 0.1 6.2 0.0 3.2 0.0 0.0 0.0 1.8 0.3 5.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.4 17.0 106.8 48.3 23.6 21.3 8.6 24.2 7.2 0.0 4.2 21.5 0.2 12.8 5.5 100.2 0.0 4.6 7.0 0.4 0.6 180.7 3.2 3.0 3.9 1.5 3.4 3.7 12.5 9.2 0.0 1.1 0.0 2.2 15.9 36.3 2.2 0.8 6.0 0.0 3526.5 3.1 0.5 1.8 0.0 31.5 0.0 0.8 1.4 0.1 0.7 116.1 5083.8 0.6 4.1 0.0 0.3 18.9 7.5 0.3 17.8 88.1 0.0 54.3 0.0 328.2 2145.0 0.7 0.2 6.4 1.2 7.5 0.0 0.1 9.3 10.7 0.0 0.4 2.2 2.1 0.8 0.1 0.9 37.9 0.6 0.0 1.0 3.0 NTHL1 "NTH1, OCTS3" ENSG00000065057 "Nth like DNA glycosylase 1" P78549 16 2039815-2047866 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 10 "Hepatocytes: 866.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025152 Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "CAB025152: " "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.23e-1)" "unprognostic (2.54e-1)" "unprognostic (7.89e-2)" "unprognostic (1.77e-1)" "unprognostic (2.86e-1)" "unprognostic (2.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "unprognostic (2.77e-2)" "unprognostic (6.78e-2)" "unprognostic (6.53e-2)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (5.08e-2)" "unprognostic (1.62e-2)" 11.7 9.3 13.8 6.2 14.7 4.7 11.0 14.8 19.7 15.5 11.1 16.8 6.6 15.4 3.1 11.3 13.8 6.0 15.8 13.5 14.2 9.8 21.9 10.7 8.4 15.4 13.9 16.1 9.9 4.8 11.5 5.6 15.6 11.2 5.6 1.8 16.0 11.5 9.7 9.3 11.1 5.3 13.6 16.7 13.2 8.7 15.2 7.6 9.6 6.8 5.9 11.8 12.5 14.2 29.8 74.2 20.8 32.2 8.5 15.9 22.8 12.1 13.2 23.1 14.6 53.0 28.8 63.0 25.2 10.7 15.1 26.2 26.1 29.0 4.0 28.9 63.3 19.5 47.7 60.9 11.5 22.4 22.3 13.2 14.9 12.3 13.2 15.4 33.4 37.0 22.2 22.6 9.0 34.9 33.9 88.3 46.2 37.3 47.3 80.8 22.0 103.5 17.2 10.7 43.9 43.5 13.2 41.0 25.4 7.6 29.6 23.5 12.9 19.9 21.5 17.5 23.1 30.3 38.0 26.9 8.8 31.7 24.9 4.2 15.0 3.4 14.4 26.0 16.2 37.5 17.3 16.7 25.7 32.8 12.8 15.4 0.7 19.1 22.5 26.3 34.0 14.4 13.8 14.7 14.8 19.7 13.5 14.2 15.4 13.9 15.6 13.6 15.2 14.2 47.2 28.9 27.5 2.9 12.9 8.7 16.4 21.6 8.0 8.8 18.9 23.4 14.1 44.3 28.3 3.7 0.0 10.5 8.1 75.6 17.6 16.3 8.1 20.4 19.5 36.5 67.4 26.7 3.0 9.1 18.3 17.6 16.3 23.3 5.7 20.5 51.0 866.4 13.4 6.7 3.6 85.3 54.9 25.5 17.6 23.8 33.8 9.3 21.4 2.8 9.7 10.7 18.6 3.0 4.9 12.1 81.6 25.2 16.0 6.4 12.8 28.8 23.5 8.1 13.1 8.1 23.6 5.4 32.0 11.7 10.1 2.7 12.2 20.6 56.8 21.0 NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 321.8;choroid plexus: 89.2;retina: 74.8" "Group enriched" "Detected in many" 5 "Alveolar cells type 1: 608.9;Astrocytes: 2164.2;Cone photoreceptor cells: 950.8;Excitatory neurons: 651.0;Inhibitory neurons: 1056.6;Oligodendrocyte precursor cells: 1930.7;Oligodendrocytes: 1257.6;Rod photoreceptor cells: 1415.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.4" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.4" "Cell line enhanced" "Detected in many" "LHCN-M2: 122.4;U-138 MG: 47.7;U-2 OS: 81.8;WM-115: 166.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" NA NA 58000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB024875: " "unprognostic (1.52e-2)" "unprognostic (4.38e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-1)" "unprognostic (1.07e-1)" "unprognostic (9.99e-3)" "unprognostic (9.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.10e-8)" "unprognostic (4.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (9.31e-3)" 17.9 4.7 137.2 2.3 138.8 0.0 2.9 165.1 321.8 1.6 89.2 12.0 2.5 1.3 0.6 9.4 0.9 9.6 30.5 136.9 131.5 2.3 0.3 25.8 0.4 144.0 135.4 0.3 0.9 22.1 0.9 0.7 143.6 1.9 3.8 74.8 2.7 2.8 0.9 6.1 4.6 4.5 135.0 0.5 2.0 0.6 154.2 0.5 1.1 5.0 0.4 3.5 1.8 158.4 0.1 0.0 7.5 0.1 0.9 22.2 0.0 36.7 19.5 11.7 6.8 0.1 0.0 0.0 0.0 20.3 0.0 0.3 0.0 43.6 12.6 0.1 0.4 0.0 0.0 0.4 0.4 0.0 0.2 2.0 0.0 38.0 45.0 29.0 7.5 0.0 0.0 0.3 122.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 3.9 20.8 0.0 2.4 3.8 0.0 0.0 0.2 1.3 0.0 0.1 8.1 47.7 81.8 2.2 31.6 0.0 0.0 0.2 0.1 0.0 166.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 137.2 138.8 165.1 321.8 136.9 131.5 144.0 135.4 143.6 135.0 154.2 158.4 1.2 608.9 27.6 2164.2 0.0 1.8 0.0 1.5 2.2 225.3 0.9 4.4 13.7 0.0 29.7 20.2 950.8 0.0 5.4 0.4 0.0 0.6 10.9 0.0 0.5 2.9 0.0 2.7 651.0 0.0 0.0 22.2 0.5 0.0 53.0 0.1 0.7 0.0 0.1 40.4 1056.6 0.1 0.0 0.0 3.8 2.2 0.3 0.7 3.6 139.6 0.0 30.5 0.0 1930.7 1257.6 0.1 0.2 0.4 0.1 0.1 0.0 0.1 1.5 1415.0 0.0 20.6 7.5 0.4 0.9 0.5 4.8 0.0 0.8 0.0 0.8 0.1 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.0" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 104.1;Fibroblasts: 326.2;Leydig cells: 166.2;Peritubular cells: 212.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Group enriched" "Detected in some" 4 "ASC TERT1: 22.2;HSkMC: 9.7;JURKAT: 15.7;MOLT-4: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" NA NA 170000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" 100.1 22.5 1.4 6.0 3.0 0.2 53.8 4.7 6.8 216.0 11.0 43.0 10.6 130.5 44.9 30.8 67.1 164.7 79.8 1.7 2.3 6.4 4.1 18.6 2.1 1.8 1.8 91.8 11.1 117.3 19.1 22.7 2.0 57.9 32.2 0.0 3.2 19.3 2.6 3.8 23.6 118.0 2.3 2.4 22.0 13.3 2.2 4.5 14.7 22.0 5.6 54.0 23.3 2.1 0.0 0.0 0.0 0.0 4.4 22.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 9.7 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.1 32.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 1.4 3.0 4.7 6.8 1.7 2.3 1.8 1.8 2.0 2.3 2.2 2.1 10.3 6.4 1.5 1.0 0.4 4.2 0.1 0.0 1.2 0.6 0.7 0.4 2.6 10.0 7.4 3.7 0.0 2.0 0.6 0.1 0.0 0.0 1.2 2.9 104.1 5.2 0.0 0.0 1.9 0.0 1.7 326.2 7.7 1.7 1.3 0.0 20.0 0.1 4.6 0.0 1.8 0.0 0.0 0.3 11.1 4.2 166.2 2.3 1.8 16.9 0.2 0.1 0.0 2.0 1.6 0.0 0.0 212.1 0.7 0.4 0.0 0.0 2.9 0.2 6.6 4.7 22.7 0.6 0.6 0.7 4.5 5.7 2.1 1.6 0.0 0.2 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.3" "Cell type enhanced" "Detected in many" "Early spermatids: 122.5;Hofbauer cells: 38.4;Skeletal myocytes: 175.5;Smooth muscle cells: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 39.7;HSkMC: 113.3;RH-30: 88.5" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" NA NA 12000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" 23.4 6.9 4.2 19.2 7.5 0.4 14.7 2.4 5.6 16.8 6.0 18.3 2.1 16.2 5.0 3.9 11.4 48.3 6.6 5.7 3.4 3.1 0.8 15.3 14.0 3.7 4.0 4.2 1.4 3.5 2.8 40.6 4.7 5.3 2.9 0.2 10.4 6.9 10.2 10.1 5.5 22.0 3.0 10.2 3.3 15.9 9.8 3.7 20.8 6.5 11.2 16.8 7.3 4.2 0.1 0.4 6.6 2.2 21.0 39.7 0.0 2.3 10.6 4.3 11.8 0.0 0.2 0.0 0.3 25.7 4.3 0.0 0.6 0.1 2.5 0.0 0.8 0.5 0.2 0.0 0.3 0.1 0.8 113.3 0.0 5.3 0.0 2.1 0.7 0.0 0.0 1.0 19.3 0.1 0.1 0.2 2.1 0.0 1.0 0.2 88.5 8.9 1.6 0.1 0.8 0.3 9.1 0.0 0.6 19.6 0.0 0.1 0.1 2.7 0.7 4.0 3.6 0.0 0.1 0.0 25.1 2.7 1.3 0.0 0.4 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 5.5 0.0 0.0 0.2 4.2 7.5 2.4 5.6 5.7 3.4 3.7 4.0 4.7 3.0 9.8 4.2 4.1 0.0 0.6 0.0 0.2 3.3 0.1 0.1 0.0 0.1 0.4 1.0 3.0 1.5 0.7 1.8 0.0 0.3 0.1 0.0 0.0 0.0 122.5 1.2 24.9 1.7 0.0 0.4 2.8 0.0 0.3 21.9 0.0 0.7 1.3 1.1 1.1 0.2 38.4 0.0 0.9 0.1 0.0 31.1 9.0 12.9 20.8 16.6 1.8 8.4 0.9 0.8 0.0 0.0 2.9 0.0 0.0 29.3 0.1 0.1 0.0 0.1 0.1 0.1 6.6 175.5 57.2 8.8 1.7 0.1 2.3 0.3 0.6 16.4 0.0 0.0 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OPHN1 "ARHGAP41, MRX60, OPN1" ENSG00000079482 "Oligophrenin 1" O60890 X 67949349-68433913 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Neurogenesis" "GTPase activation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.8" "Group enriched" "Detected in many" 5 "Astrocytes: 383.9;Oligodendrocyte precursor cells: 600.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002919 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Plasma membrane" "HPA002919: AB_1079526" "unprognostic (1.21e-1)" "unprognostic (3.21e-2)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (3.85e-3)" "unprognostic (4.32e-2)" "unprognostic (3.52e-2)" "unprognostic (3.09e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (4.37e-2)" "unprognostic (2.30e-1)" "unprognostic (2.21e-4)" "unprognostic (1.98e-1)" "unprognostic (1.29e-2)" "unprognostic (2.08e-3)" "unprognostic (2.64e-3)" 4.1 5.1 20.8 1.8 18.6 3.9 4.5 14.2 19.5 6.0 1.0 3.4 2.5 5.6 3.7 3.8 3.2 2.7 3.1 18.0 14.6 4.3 1.3 4.4 1.9 9.5 11.9 4.5 3.1 3.6 2.7 5.6 5.8 10.1 3.4 11.5 5.4 5.0 6.5 6.4 2.9 4.0 6.1 2.3 3.8 2.6 16.3 1.2 4.7 4.8 1.4 2.3 3.8 11.5 23.6 5.1 3.2 7.3 7.1 6.8 5.0 4.2 5.6 8.3 10.1 3.3 4.5 1.5 13.7 4.9 3.4 5.7 3.1 2.9 12.6 0.9 2.1 5.2 6.9 3.7 2.4 2.1 5.2 4.6 4.8 6.9 6.4 10.6 5.6 1.1 3.2 3.1 4.3 10.1 0.8 1.8 7.5 10.0 4.8 0.9 7.3 1.3 8.5 7.6 1.7 2.8 7.2 9.1 13.7 7.1 6.2 1.6 6.0 5.0 7.3 18.1 4.5 2.9 3.4 1.0 4.0 2.8 3.5 1.0 1.0 0.4 0.5 0.4 0.4 0.5 0.4 0.3 0.4 0.8 0.4 0.5 4.6 0.5 0.6 1.6 0.3 0.2 20.8 18.6 14.2 19.5 18.0 14.6 9.5 11.9 5.8 6.1 16.3 11.5 13.8 16.0 19.3 383.9 0.0 3.2 5.4 2.0 10.2 5.4 6.7 5.0 3.3 2.8 6.4 18.4 6.2 23.0 2.3 3.9 0.0 1.2 2.0 7.2 4.3 8.1 4.2 1.3 84.6 0.8 11.7 18.0 14.8 12.9 8.8 36.3 5.0 0.2 4.6 0.0 78.8 3.0 2.0 2.1 9.5 1.7 21.1 5.9 8.8 54.4 1.2 16.0 3.1 600.2 41.7 1.3 2.4 12.0 0.1 8.5 3.8 1.8 10.9 5.1 0.0 24.1 5.4 0.3 1.9 8.9 5.1 66.9 1.4 4.2 4.1 4.2 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 PAGR1 "C16orf53, GAS, MGC4606, PA1" ENSG00000280789 "PAXIP1 associated glutamate rich protein 1" Q9BTK6 16 29816152-29822489 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 166.5" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Plasma cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041440, HPA043608" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" "HPA041440: AB_10795541, HPA043608: AB_10797144" "unprognostic (2.35e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" "unprognostic (1.44e-2)" "unprognostic (4.20e-1)" "unprognostic (1.14e-3)" "unprognostic (7.09e-3)" "unprognostic (5.12e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-1)" "unprognostic (1.84e-3)" "unprognostic (3.41e-2)" "unprognostic (1.51e-2)" "unprognostic (8.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (5.39e-2)" 23.5 27.8 10.2 5.5 10.8 6.5 23.2 18.4 12.3 120.8 8.9 48.9 8.7 55.3 7.1 25.7 68.4 6.1 32.0 10.1 9.9 30.4 28.1 23.0 8.7 10.9 10.7 166.5 26.3 7.4 128.9 3.7 10.8 69.3 5.7 6.8 21.4 8.8 24.6 18.0 30.8 4.7 10.5 23.6 26.4 31.2 10.6 9.3 30.2 9.0 6.8 50.7 73.8 12.5 16.7 24.1 13.9 8.7 7.0 6.7 11.8 12.7 11.5 14.5 12.7 17.1 16.9 33.4 12.7 9.1 7.2 15.4 15.2 19.1 9.2 14.8 31.1 14.8 16.4 16.1 7.3 23.6 26.9 7.5 15.1 10.2 10.0 13.4 12.1 31.0 20.1 10.4 9.9 45.2 18.6 27.6 19.3 14.2 20.4 35.4 24.5 24.9 10.8 7.8 34.9 13.2 9.6 22.4 9.7 10.5 20.9 15.0 9.2 12.0 10.9 15.2 12.9 19.4 21.3 13.1 15.8 24.2 15.0 22.5 16.9 33.0 19.7 17.0 22.1 19.7 16.8 20.0 21.3 19.5 21.7 20.1 11.0 13.9 19.6 21.5 12.7 15.2 10.2 10.8 18.4 12.3 10.1 9.9 10.9 10.7 10.8 10.5 10.6 12.5 1.3 0.0 9.8 66.6 15.2 0.0 0.3 0.1 18.2 3.5 4.7 2.9 0.6 14.3 6.9 1.8 0.0 5.6 5.3 5.9 0.0 27.9 0.5 1.0 1.3 3.8 14.6 10.7 16.2 21.7 8.2 4.4 13.3 0.8 7.6 0.3 6.1 2.0 7.5 5.0 16.5 11.1 0.0 5.6 0.0 0.6 0.9 7.7 0.0 9.4 22.5 1.9 4.1 11.6 8.6 13.5 15.8 3.4 34.5 0.7 20.7 2.1 3.0 3.3 0.0 0.9 5.0 3.1 1.6 16.7 0.4 6.7 10.9 0.2 13.2 0.2 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PARD3B "ALS2CR19, PAR3beta, Par3L" ENSG00000116117 "Par-3 family cell polarity regulator beta" Q8TEW8 2 204545475-205620162 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 490.7;Microglial cells: 183.6;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;BJ hTERT+: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035283 Approved Supported "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions" "HPA035283: AB_10671102" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.67e-10)" "unprognostic (1.74e-1)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (8.09e-2)" 9.1 2.8 6.0 1.7 7.3 0.0 5.5 5.3 5.3 4.9 9.3 12.6 3.6 5.1 3.7 4.0 6.5 4.5 4.0 4.6 9.2 6.9 3.4 5.4 2.1 9.3 12.2 7.3 4.9 9.2 1.9 4.4 8.3 4.8 5.5 2.5 3.0 5.2 2.7 4.5 4.2 5.2 8.4 3.1 4.5 3.8 8.0 1.4 5.6 3.6 2.5 5.9 4.0 7.4 2.5 2.1 6.3 2.3 17.8 8.9 3.4 3.8 12.5 3.5 3.8 6.2 1.7 0.0 4.3 7.8 2.8 0.3 0.8 1.0 3.6 0.2 2.9 8.8 5.2 0.0 1.8 0.0 0.5 3.4 1.7 1.2 5.2 5.3 5.2 0.8 0.2 0.1 4.5 1.0 0.0 0.0 0.8 0.9 0.5 0.0 2.7 2.1 3.7 2.5 0.7 2.0 2.0 1.9 1.7 6.2 3.1 0.0 10.9 2.7 1.7 5.5 1.8 0.0 0.0 0.0 2.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.3 5.3 5.3 4.6 9.2 9.3 12.2 8.3 8.4 8.0 7.4 9.5 9.6 8.6 490.7 0.5 11.0 3.3 2.4 6.8 0.5 5.6 5.8 10.8 15.7 14.5 29.5 0.0 3.2 0.2 12.4 0.0 8.7 76.6 8.5 4.0 6.8 6.0 0.8 5.6 2.4 0.2 16.2 11.7 7.4 1.3 14.1 8.2 4.5 0.5 5.0 50.8 9.2 2.0 1.0 4.3 26.0 31.1 0.6 7.2 183.6 0.1 9.7 0.0 159.3 104.2 6.5 15.9 57.9 1.4 5.0 9.4 4.8 17.0 0.3 19.7 23.5 9.6 1.4 2.9 3.5 4.7 1.1 1.0 2.3 8.0 5.3 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PDE5A ENSG00000138735 "Phosphodiesterase 5A" O76074 4 119494397-119628804 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.1;Inhibitory neurons: 58.3;Oligodendrocyte precursor cells: 56.8;Peritubular cells: 104.9;Smooth muscle cells: 80.9" "Group enriched" "Detected in all" 4 "prostate cancer: 7.0;thyroid cancer: 27.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 47.5;HHSteC: 65.9;hTERT-RPE1: 24.6" "Region enhanced" "Detected in all" "cerebellum: 18.2" "Low region specificity" "Detected in all" "HPA004729, HPA012873" Approved Approved Cytosol NA NA 850000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA004729: AB_1079588, HPA012873: AB_1855124" "unprognostic (6.95e-2)" "prognostic favorable (5.20e-4)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (7.36e-2)" "unprognostic (2.58e-2)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.16e-2)" "unprognostic (1.52e-2)" "unprognostic (8.98e-2)" "unprognostic (8.71e-3)" "prognostic unfavorable (1.17e-4)" 15.4 11.3 0.9 10.9 3.5 2.1 9.6 4.9 3.7 32.7 12.6 37.0 15.5 14.4 41.5 41.3 22.9 10.4 12.8 1.4 3.6 5.9 1.5 22.1 6.4 4.9 8.2 5.4 12.4 8.3 3.5 13.2 5.2 59.8 25.9 9.6 9.8 49.8 6.9 5.0 18.9 11.4 0.0 5.8 9.6 9.4 3.4 3.7 16.8 5.6 3.5 14.6 15.8 1.9 16.7 0.8 11.0 1.2 3.7 5.5 1.9 10.7 47.5 0.5 1.0 1.0 1.3 1.6 0.5 13.4 3.0 5.8 3.5 1.7 1.3 0.4 7.4 18.5 2.6 0.9 65.9 3.9 1.7 6.1 3.3 1.1 0.1 24.6 1.4 3.7 2.0 2.9 1.6 0.9 5.0 0.6 2.3 1.8 2.8 0.7 5.9 4.3 4.1 4.9 4.3 8.8 13.0 15.3 1.3 8.1 2.7 2.1 2.5 6.2 5.2 3.4 1.5 4.1 2.0 1.5 5.9 1.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.4 0.3 0.1 0.0 0.3 0.1 0.2 0.4 0.2 0.1 0.1 0.1 1.2 0.9 3.5 4.9 3.7 1.4 3.6 4.9 8.2 5.2 0.0 3.4 1.9 7.8 6.4 3.9 19.9 1.3 3.4 2.8 1.1 5.7 8.1 11.0 8.4 5.5 14.3 3.7 1.8 14.6 0.4 0.9 15.5 0.0 15.8 30.6 5.0 12.6 7.8 2.4 0.0 66.1 2.9 0.3 28.1 1.1 3.9 1.3 1.6 0.7 0.9 0.3 5.0 58.3 9.5 2.0 0.0 3.5 11.5 20.8 11.3 5.4 40.3 1.3 28.5 2.1 56.8 41.1 3.9 10.3 104.9 1.4 3.6 7.9 0.5 0.8 5.8 19.7 5.5 80.9 5.4 6.3 3.5 2.4 0.3 1.7 7.0 11.1 2.6 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 PDZD4 "FLJ34125, KIAA1444, LNX5, LU1, PDZK4, PDZRN4L" ENSG00000067840 "PDZ domain containing 4" Q76G19 X 153802166-153830565 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 150.1" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Bipolar cells: 18.0;dendritic cells: 14.0;Excitatory neurons: 11.0;NK-cells: 26.8;Rod photoreceptor cells: 14.1" "Group enriched" "Detected in many" 4 "glioma: 20.1;testis cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 24.4;NTERA-2: 12.4;RH-30: 17.3;SCLC-21H: 29.5;SH-SY5Y: 28.7;U-2 OS: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003878 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "HPA003878: AB_2162807" "unprognostic (9.18e-3)" "unprognostic (1.25e-1)" "unprognostic (1.11e-4)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (1.85e-2)" "unprognostic (1.92e-3)" "unprognostic (2.17e-1)" "unprognostic (2.32e-3)" "unprognostic (5.90e-2)" "prognostic favorable (2.96e-5)" "unprognostic (2.27e-1)" "unprognostic (2.54e-4)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.83e-2)" "unprognostic (2.87e-2)" 3.7 5.0 98.2 1.9 102.8 2.1 3.4 76.6 150.1 9.5 42.3 23.4 1.6 11.9 1.2 3.8 13.9 2.0 6.1 132.0 46.9 3.9 2.6 4.8 2.0 57.6 48.0 2.7 2.3 2.8 44.1 0.1 59.5 10.4 1.3 14.8 4.1 9.8 3.3 4.3 5.9 4.3 38.2 14.0 7.6 6.0 46.7 1.1 3.5 1.3 0.6 10.0 9.2 89.8 0.0 1.6 24.4 6.4 0.0 0.1 0.0 0.7 0.0 0.7 0.8 0.6 0.0 0.0 0.3 0.0 7.9 0.1 4.5 0.0 0.1 0.0 0.8 0.0 1.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.1 0.3 5.0 0.2 0.9 12.4 0.0 0.3 0.1 17.3 0.0 0.0 0.1 29.5 28.7 1.3 0.0 9.2 8.2 2.8 0.3 0.0 0.0 14.1 0.3 1.8 0.0 0.1 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.2 98.2 102.8 76.6 150.1 132.0 46.9 57.6 48.0 59.5 38.2 46.7 89.8 1.8 0.0 0.0 12.1 0.1 0.3 0.0 0.0 0.6 18.0 0.1 2.4 3.7 0.0 1.3 0.0 6.2 0.0 14.0 0.0 0.0 0.0 0.1 0.2 1.5 3.5 1.8 0.8 11.0 0.2 0.0 0.8 0.5 0.1 1.3 0.2 4.6 0.1 0.0 1.7 8.6 0.0 0.0 1.0 0.0 0.2 0.6 0.1 3.6 4.7 0.2 3.9 26.8 5.5 0.7 0.3 0.0 3.8 3.6 0.2 0.0 0.0 4.4 14.1 0.0 1.7 2.1 0.3 4.1 0.5 0.9 0.0 4.1 0.0 0.0 0.2 PHLDA3 TIH1 ENSG00000174307 "Pleckstrin homology like domain family A member 3" Q9Y5J5 1 201464278-201469237 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 269.3;Prostatic glandular cells: 188.7;Urothelial cells: 556.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 284.8;WM-115: 164.3" "Low region specificity" "Detected in all" HPA027601 Approved NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA027601: AB_10601389" "unprognostic (1.51e-1)" "unprognostic (7.48e-2)" "unprognostic (5.65e-2)" "prognostic favorable (1.77e-4)" "unprognostic (8.55e-3)" "unprognostic (4.34e-3)" "unprognostic (5.55e-3)" "unprognostic (1.42e-1)" "unprognostic (2.16e-3)" "unprognostic (8.65e-2)" "unprognostic (8.78e-2)" "unprognostic (7.65e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (9.32e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (7.45e-2)" 155.6 30.0 34.9 8.4 50.6 0.3 119.3 51.2 41.9 56.8 21.3 139.4 4.1 52.9 11.6 89.4 40.8 15.3 40.9 31.7 39.4 18.2 8.1 41.6 2.5 73.4 50.3 23.5 23.4 10.7 28.4 8.9 51.3 64.8 5.5 3.0 39.3 26.8 75.9 68.3 29.0 17.8 45.2 10.4 35.1 8.9 52.1 10.1 31.5 11.6 4.9 75.5 68.4 69.2 52.4 60.8 11.1 33.5 50.6 47.7 284.8 75.6 57.3 18.2 21.0 4.0 39.5 0.1 3.1 37.6 15.7 90.0 1.0 61.0 3.6 0.0 22.4 0.0 26.2 47.6 57.4 0.0 1.0 66.7 90.6 29.4 25.8 53.5 26.3 4.5 0.0 0.1 36.7 37.5 8.0 0.8 19.1 0.0 3.8 2.5 51.9 0.0 16.9 115.1 0.7 11.7 26.5 0.8 62.7 42.5 25.0 3.6 39.4 42.2 69.6 36.1 16.2 1.4 0.2 0.1 102.4 0.1 164.3 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.2 0.0 0.1 0.6 0.0 34.9 50.6 51.2 41.9 31.7 39.4 73.4 50.3 51.3 45.2 52.1 69.2 83.3 9.6 9.1 8.8 0.9 78.1 269.3 48.8 93.9 5.2 29.8 42.4 6.2 2.8 30.7 49.7 0.0 84.9 1.8 2.2 11.7 42.0 36.8 42.7 15.2 22.2 5.3 2.7 5.7 18.9 24.4 43.3 7.1 31.8 0.0 11.2 10.4 1.4 18.1 0.0 8.3 2.1 10.2 0.6 28.5 136.5 26.8 7.9 32.0 1.0 18.2 105.4 1.0 4.5 37.1 71.4 2.9 41.8 2.1 188.7 1.2 8.5 22.3 5.2 0.0 38.0 55.8 0.8 4.0 92.1 102.0 37.5 5.7 46.5 3.6 556.5 PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 140.6;heart muscle: 127.7;vagina: 127.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 204.8;Leydig cells: 205.9;Oligodendrocytes: 67.3;Peritubular cells: 149.7" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.1" "Lineage enriched" "Detected in many" 5 "T-cells: 66.1" "Cell line enriched" "Detected in some" 6 "JURKAT: 29.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 7 "spinal cord: 33.2" HPA076574 Approved "Secreted to blood" NA NA 2900000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" 57.8 3.5 12.2 3.1 17.7 0.2 66.1 14.3 15.1 140.6 7.9 11.6 1.5 5.7 29.0 10.6 15.0 46.4 127.7 10.1 16.1 1.5 0.7 11.4 2.2 15.3 14.2 3.4 5.6 0.9 8.4 2.4 15.8 31.3 7.9 0.0 14.0 34.2 15.1 51.7 4.5 8.4 13.4 1.3 22.1 14.7 16.4 2.4 23.2 33.6 6.0 116.1 127.6 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.9 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 29.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 1.8 0.6 19.7 5.7 0.0 1.3 6.4 2.2 0.5 13.5 0.0 0.5 66.1 3.3 12.2 17.7 14.3 15.1 10.1 16.1 15.3 14.2 15.8 13.4 16.4 19.3 10.9 0.0 1.5 3.3 0.7 21.5 0.1 0.0 0.6 0.0 0.4 0.4 4.5 0.0 0.6 1.8 0.0 0.0 0.4 0.0 1.9 0.1 10.8 0.1 0.2 11.0 0.0 0.0 0.1 0.0 0.0 204.8 4.1 0.1 0.0 0.0 10.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 39.6 19.0 205.9 1.9 10.6 3.7 0.0 0.0 0.0 0.0 67.3 0.1 0.0 149.7 0.6 0.1 0.0 0.2 0.0 0.0 0.0 7.7 4.2 2.4 1.3 0.4 18.5 0.1 3.5 0.3 0.0 0.2 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 26.2;Cytotrophoblasts: 32.6;Distal tubular cells: 49.0;Extravillous trophoblasts: 31.1;Hofbauer cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 76.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 11.9 13.9 13.2 6.6 15.7 30.0 7.4 16.5 20.1 9.2 20.2 14.6 2.8 10.5 4.2 5.9 7.2 11.0 20.7 13.3 20.4 10.0 3.8 5.5 6.9 16.5 16.4 10.6 3.3 10.9 7.9 8.8 18.2 8.7 4.8 11.0 7.3 12.2 13.5 6.5 5.3 13.5 16.4 8.3 6.5 6.9 17.5 9.5 6.6 14.8 5.4 9.9 6.6 21.0 4.8 2.9 16.8 10.2 27.2 30.6 3.5 19.3 24.2 10.2 15.1 1.9 8.1 9.4 2.6 19.9 10.3 1.1 4.2 7.0 13.6 8.1 7.3 13.9 2.9 1.5 23.6 3.3 12.2 17.2 4.4 12.8 9.6 27.4 9.8 2.7 7.4 31.0 35.6 3.3 10.4 9.5 8.6 0.0 9.8 3.9 6.9 11.2 14.9 3.0 2.0 9.7 1.5 6.6 28.4 11.4 0.2 6.3 15.1 18.5 7.1 11.2 9.0 12.0 7.0 6.0 31.6 6.4 25.2 0.9 11.6 10.8 1.3 5.9 2.3 2.7 3.1 1.7 10.8 1.9 4.8 1.9 76.9 2.4 2.2 6.0 2.8 6.1 13.2 15.7 16.5 20.1 13.3 20.4 16.5 16.4 18.2 16.4 17.5 21.0 26.2 0.0 2.8 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.5 11.2 0.0 0.0 3.1 9.2 0.0 32.6 7.7 0.0 49.0 18.0 0.0 0.8 11.7 5.2 0.0 0.0 0.0 8.9 31.1 18.7 0.0 1.0 8.8 4.1 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.1 0.0 0.0 13.1 1.5 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 10.9 3.7 14.3 0.0 0.0 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 124.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 926.5;Leydig cells: 873.5;Peritubular cells: 659.7;Sertoli cells: 295.9;Smooth muscle cells: 446.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 98.5;ASC TERT1: 85.3;BEWO: 32.1;HSkMC: 28.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 37.9" HPA043469 Uncertain "Secreted - unknown location" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" 112.3 18.4 10.2 6.6 9.2 1.2 85.7 10.3 15.5 77.3 53.3 22.1 4.0 26.9 5.0 21.4 30.4 9.0 124.3 14.3 5.9 17.9 6.4 56.1 2.7 5.9 5.8 11.5 5.7 4.1 4.9 12.5 6.4 35.9 4.6 0.6 20.1 7.6 16.9 47.8 19.7 6.5 6.5 5.0 21.4 14.9 6.9 2.2 44.6 19.2 1.9 54.0 75.7 8.5 0.2 0.0 0.8 0.0 98.5 85.3 32.1 10.3 8.7 0.9 1.2 0.0 0.7 0.0 0.2 6.0 0.1 0.8 0.1 0.0 0.0 0.8 0.3 0.0 0.5 0.0 16.4 0.0 2.3 28.7 0.0 2.1 1.2 10.6 3.4 0.4 0.0 0.4 0.0 0.3 0.1 0.6 1.9 0.4 1.5 0.0 0.1 1.5 0.0 0.6 0.0 1.8 0.0 1.2 0.7 0.2 0.1 0.2 3.6 6.6 3.6 21.0 0.2 0.7 0.9 0.1 1.9 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 10.2 9.2 10.3 15.5 14.3 5.9 5.9 5.8 6.4 6.5 6.9 8.5 246.2 3.2 1.8 0.0 1.6 126.4 0.7 1.1 8.0 0.4 7.4 14.0 24.4 0.0 0.3 0.0 0.0 7.0 3.6 0.1 0.0 0.3 4.6 3.1 75.7 102.5 1.8 0.0 0.5 0.2 17.7 926.5 5.6 4.4 1.3 0.1 115.6 0.3 14.1 0.0 0.5 0.0 0.0 0.0 191.3 26.7 873.5 7.9 136.9 7.5 0.0 50.2 0.0 0.0 0.2 0.7 0.0 659.7 2.1 1.0 0.0 0.2 0.9 1.7 295.9 89.7 446.6 2.6 2.9 4.6 126.3 11.5 14.1 1.1 0.0 1.8 PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 252.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.6;Leydig cells: 138.5;Theca cells: 205.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 99.0;RH-30: 94.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: AB_2682893" "unprognostic (4.74e-3)" "unprognostic (8.35e-3)" "unprognostic (5.43e-2)" "unprognostic (1.74e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.32e-2)" "unprognostic (6.17e-2)" "unprognostic (3.49e-2)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.94e-6)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.69e-2)" "unprognostic (5.17e-3)" "unprognostic (4.93e-3)" 37.7 74.8 4.1 18.5 5.2 21.7 29.6 1.9 7.0 31.4 5.8 28.8 9.6 29.5 9.0 32.9 20.8 26.9 26.4 3.8 2.9 17.0 3.6 26.7 12.1 3.6 4.1 36.5 27.7 9.5 81.6 252.3 3.9 26.0 21.3 1.6 30.1 12.1 12.2 61.9 20.6 19.7 3.2 15.6 26.9 8.7 6.0 6.6 13.8 22.3 12.1 39.6 34.4 4.0 0.2 5.0 99.0 0.1 39.4 78.0 0.3 32.9 21.6 16.1 33.5 0.3 6.0 2.7 16.0 30.4 4.0 0.0 0.8 12.0 32.2 3.1 4.4 45.2 58.7 0.9 13.9 40.9 8.9 60.5 4.6 15.8 13.8 23.4 33.5 16.1 4.4 0.8 18.0 6.2 16.9 19.8 17.2 0.0 3.7 20.7 94.1 0.1 33.1 1.1 8.7 10.3 51.0 0.1 0.1 29.6 0.1 50.1 19.8 0.2 35.2 77.7 36.4 9.1 9.0 0.6 25.3 16.6 2.0 4.9 12.0 25.1 1.4 9.1 1.4 3.7 1.3 1.9 14.9 5.8 0.9 1.5 21.7 2.2 2.9 6.7 2.0 3.8 4.1 5.2 1.9 7.0 3.8 2.9 3.6 4.1 3.9 3.2 6.0 4.0 19.5 51.3 51.0 28.4 15.2 21.7 14.6 5.3 34.1 2.1 16.8 14.0 8.4 5.7 12.6 5.5 0.0 4.6 19.0 16.1 7.9 11.8 1.8 8.6 91.9 23.8 16.7 19.3 60.3 11.3 15.0 143.6 11.7 13.0 18.4 38.7 8.6 0.2 20.3 8.4 76.6 33.6 18.3 26.8 27.8 5.5 138.5 26.8 8.8 49.6 37.6 0.9 2.1 10.6 5.5 13.0 22.5 97.0 5.7 52.0 4.3 15.3 4.4 0.4 13.1 61.7 31.1 0.9 1.0 24.1 43.3 9.9 10.0 205.8 28.5 19.7 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28644142 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 39.0" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 112.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 3.0;eosinophil: 3.0;intermediate monocyte: 4.4;myeloid DC: 5.7;neutrophil: 8.8;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 40 "dendritic cells: 5.7;granulocytes: 8.8;monocytes: 5.0" "Cell line enhanced" "Detected in some" "BEWO: 3.6;OE19: 7.8;RT4: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" 1.8 5.7 3.4 1.8 3.3 5.0 1.8 1.0 3.0 1.9 2.2 1.5 0.7 1.6 1.7 1.0 1.3 1.5 1.2 2.7 2.6 0.7 0.5 1.6 0.4 2.4 2.3 0.9 0.6 0.3 1.6 2.1 2.0 2.1 1.8 0.1 1.4 1.5 2.0 7.9 39.0 2.7 2.5 4.1 0.9 2.6 2.9 0.6 2.0 0.6 0.3 1.7 1.3 1.6 0.4 0.0 2.4 0.0 0.5 0.3 3.6 0.1 1.0 0.2 0.2 2.5 0.2 0.2 0.2 0.4 1.0 0.5 0.0 1.9 0.2 0.1 0.0 0.2 0.4 0.4 0.8 0.4 0.1 0.4 1.1 0.4 0.5 0.4 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.1 7.8 0.5 0.0 0.4 0.0 1.1 2.7 1.0 0.2 0.1 0.1 0.2 0.2 0.0 1.3 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.8 1.8 0.0 0.0 3.0 3.0 0.0 4.4 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 8.8 0.0 5.0 0.3 0.1 1.1 3.4 3.3 1.0 3.0 2.7 2.6 2.4 2.3 2.0 2.5 2.9 1.6 0.6 0.0 0.6 0.7 0.3 0.4 1.0 0.6 0.6 0.1 1.6 1.5 1.6 0.0 1.5 0.0 0.0 0.5 2.1 6.5 1.9 1.6 27.0 2.4 1.0 1.5 1.2 0.0 3.2 0.9 23.2 0.6 0.0 1.1 5.7 0.1 1.1 0.0 12.5 0.0 3.4 5.4 0.0 17.4 10.1 18.3 1.2 12.5 0.0 15.0 4.8 0.3 0.0 1.5 0.4 1.0 2.6 0.7 0.5 0.4 112.6 0.0 1.5 0.0 0.0 1.1 0.3 1.0 0.9 0.3 0.4 8.2 1.5 0.6 2.5 1.6 PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 187.7;Hofbauer cells: 105.6;Kupffer cells: 109.4;Macrophages: 116.3;monocytes: 192.8;Paneth cells: 105.9" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 662.9;intermediate monocyte: 204.4;myeloid DC: 357.3;neutrophil: 443.8" "Group enriched" "Detected in all" 135 "dendritic cells: 357.3;granulocytes: 443.8;monocytes: 662.9" "Cell line enhanced" "Detected in many" "AN3-CA: 48.6;BEWO: 98.4;CAPAN-2: 245.6;MCF7: 46.3" "Not detected" "Not detected" HPA040303 Enhanced "Intracellular and membrane" NA NA 3400000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" 29.4 5.6 2.1 33.7 2.5 285.9 27.8 2.4 3.7 22.4 25.9 58.8 28.2 13.5 10.6 56.3 16.6 33.1 32.6 2.1 2.4 26.3 10.6 64.0 9.2 3.5 3.2 4.4 30.0 3.2 3.4 35.9 3.2 10.2 79.2 0.8 11.9 15.3 9.9 24.8 42.6 28.1 3.1 25.2 36.6 10.0 2.8 7.8 6.1 17.2 32.7 58.5 29.6 4.8 7.1 5.0 0.5 48.6 0.3 0.0 98.4 0.2 0.0 3.0 2.4 14.1 245.6 0.0 1.4 1.0 0.4 9.4 0.0 0.0 0.5 0.0 0.1 0.0 6.4 0.0 3.8 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 21.2 0.0 1.1 46.3 0.1 0.2 16.5 0.7 0.3 0.1 0.1 0.5 0.7 28.9 0.0 0.4 30.2 14.8 1.9 26.5 9.0 9.6 0.0 0.5 0.4 0.0 0.6 8.7 23.7 0.2 0.0 0.1 0.4 0.4 662.9 5.8 1.0 204.4 0.6 3.6 0.5 0.4 357.3 0.8 0.7 0.7 443.8 1.7 73.5 4.1 0.9 423.2 2.1 2.5 2.4 3.7 2.1 2.4 3.5 3.2 3.2 3.1 2.8 4.8 15.5 9.6 8.6 0.3 2.9 6.8 8.8 4.9 6.8 0.0 11.9 6.6 16.5 30.0 20.4 33.1 0.0 94.5 1.5 67.8 11.7 13.1 51.8 2.5 9.1 7.2 9.1 1.7 1.6 46.5 187.7 59.6 13.3 0.9 5.1 5.9 4.6 2.9 105.6 0.0 0.9 31.3 6.1 109.4 68.6 5.8 26.1 116.3 5.4 7.5 192.8 1.6 1.0 1.5 0.2 28.6 105.9 27.8 3.6 3.8 52.8 15.7 19.0 0.2 0.0 12.0 10.4 17.4 12.0 17.8 19.9 70.3 1.6 6.1 75.2 30.1 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.3" "Cell type enhanced" "Detected in many" "Astrocytes: 563.5;Excitatory neurons: 2569.1;Inhibitory neurons: 1774.0;Oligodendrocyte precursor cells: 783.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 74.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 45.5;Hep G2: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" NA NA 6600 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: AB_2674311, HPA057910: AB_2683552" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 9.3 8.9 11.7 5.7 52.3 4.8 7.6 0.0 74.3 8.2 0.0 18.1 7.2 9.3 3.5 5.4 9.6 8.5 11.7 17.4 0.0 13.2 4.3 5.0 1.8 0.0 0.1 3.7 14.7 44.3 4.3 19.6 0.0 13.4 4.1 7.1 29.0 18.8 14.4 2.6 5.7 8.1 0.0 3.6 8.0 3.0 9.8 6.8 3.8 11.0 0.9 15.9 6.7 23.8 0.2 1.2 4.8 0.3 8.7 16.1 6.3 20.2 13.1 5.2 3.1 45.5 5.0 2.2 8.2 3.9 0.3 0.0 3.7 0.0 3.8 0.0 4.4 1.0 3.5 68.7 2.2 1.1 0.7 1.1 0.8 7.1 0.0 6.5 10.6 13.0 7.1 26.0 0.1 6.2 1.0 3.3 15.0 10.6 6.6 14.7 0.0 12.1 4.0 16.8 16.9 7.2 0.1 4.1 0.9 17.1 19.9 6.6 1.9 16.8 7.5 1.3 12.7 19.4 24.5 33.9 8.6 12.6 29.5 0.3 1.3 1.2 1.4 0.3 2.0 0.1 0.4 0.5 0.1 0.2 0.2 0.4 0.8 1.1 0.1 0.3 0.1 0.2 11.7 52.3 0.0 74.3 17.4 0.0 0.0 0.1 0.0 0.0 9.8 23.8 74.8 0.0 3.4 563.5 1.1 1.9 20.8 2.3 8.0 7.6 8.1 23.2 26.9 7.2 2.6 16.5 0.0 2.4 16.8 1.3 33.2 1.2 9.9 42.1 5.1 54.6 0.0 6.5 2569.1 13.4 2.8 25.8 3.6 83.6 1.3 0.2 26.4 2.8 0.8 1.7 1774.0 2.1 0.0 8.2 1.2 4.3 3.4 9.1 7.2 211.7 12.2 18.2 15.5 783.1 34.8 1.8 0.5 3.8 6.1 20.2 0.1 9.4 9.9 4.1 0.0 7.4 13.3 4.7 5.6 2.5 1.7 1.8 15.4 1.1 1.2 18.9 PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 16.2;choroid plexus: 52.8" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 319.5;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 226.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.0;AF22: 10.3;HDLM-2: 5.3;SH-SY5Y: 2.9;U-2 OS: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028389, HPA050367" Approved Vesicles,Mitochondria,Cytosol No No "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Vesicles, Cytosol" "HPA028389: AB_10602145, HPA050367: AB_2681105" "unprognostic (5.20e-2)" "unprognostic (1.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (8.77e-2)" "unprognostic (4.36e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-5)" "unprognostic (2.79e-2)" "unprognostic (4.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.18e-1)" 0.4 1.7 1.7 0.0 2.9 0.0 0.4 16.2 2.5 0.6 52.8 0.2 0.0 1.1 0.2 0.4 1.1 0.1 0.1 3.4 2.5 0.4 0.0 0.2 1.1 2.9 2.6 2.1 1.0 0.2 2.4 0.4 2.8 0.8 0.1 0.3 0.7 3.0 0.2 0.1 0.1 0.9 2.0 0.7 0.3 1.5 2.2 0.4 0.2 0.0 0.4 0.1 0.3 2.7 0.0 3.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 16.2 2.5 3.4 2.5 2.9 2.6 2.8 2.0 2.2 2.7 0.1 0.0 0.0 7.8 0.2 0.1 0.0 0.0 1.2 0.5 0.0 1.7 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 9.1 2.9 0.6 0.3 0.0 0.0 35.5 0.0 0.0 3.1 0.0 8.2 0.0 0.7 0.0 0.0 0.0 3.3 319.5 0.2 0.0 0.0 0.0 21.0 5.0 0.1 0.0 5.6 0.0 0.4 0.0 127.6 226.8 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.2 0.6 0.2 0.1 0.3 0.0 0.0 0.0 0.1 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHG5 "GEF720, KIAA0720, Syx, Tech" ENSG00000171680 "Pleckstrin homology and RhoGEF domain containing G5" O94827 1 6467122-6520074 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 57.4;skin 1: 102.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 17.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 57.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.1;TIME: 30.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049570 Uncertain Approved Nucleoplasm NA NA "Cluster 61: Skin - Cornification" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA049570: AB_2680818" "unprognostic (5.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.47e-1)" "unprognostic (2.81e-1)" "unprognostic (1.50e-3)" "unprognostic (5.10e-2)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (4.40e-2)" "unprognostic (1.02e-2)" "unprognostic (4.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.28e-3)" "unprognostic (4.85e-1)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (4.85e-2)" 18.7 15.0 4.4 2.9 2.6 0.6 12.0 57.4 16.6 14.0 0.0 7.3 6.4 7.5 1.9 21.6 8.6 7.3 16.4 13.0 0.0 6.5 1.8 6.0 5.0 0.0 0.0 7.5 5.1 4.4 43.3 12.4 1.8 9.9 3.5 3.4 9.3 7.2 6.8 102.5 8.4 3.9 0.0 50.9 4.4 5.4 0.0 2.0 7.2 3.0 3.3 5.9 14.3 0.0 7.1 2.7 11.9 9.4 1.5 4.2 3.1 8.4 7.0 3.2 2.1 6.9 18.8 0.3 22.6 2.8 4.9 22.6 2.2 23.7 1.3 16.5 3.0 0.0 15.1 2.9 1.9 0.0 1.3 5.5 10.2 8.1 12.5 17.4 24.9 1.7 0.0 1.5 0.6 5.0 0.5 32.1 4.9 2.3 23.8 0.1 2.7 2.3 6.3 3.1 10.5 25.2 1.1 8.2 1.5 5.3 8.2 0.5 30.3 8.1 5.0 0.0 6.6 0.1 0.0 2.4 9.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.6 57.4 16.6 13.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 10.6 0.0 1.5 1.0 0.2 7.4 2.3 4.7 8.0 1.4 1.4 2.2 4.1 1.5 3.6 3.7 2.1 2.6 0.1 4.2 0.0 1.3 8.6 2.5 5.9 9.8 3.5 0.4 17.4 1.3 4.0 1.9 3.1 3.2 0.0 4.0 7.5 0.3 5.3 1.7 9.6 6.4 6.1 0.8 1.3 5.7 1.8 2.4 0.0 7.5 0.0 9.7 0.0 2.0 1.2 5.1 5.6 8.6 0.4 3.8 4.1 0.4 2.7 1.5 13.1 2.1 1.7 2.1 5.1 10.8 14.5 1.9 0.7 2.5 2.8 5.8 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PMP2 "FABP8, M-FABP, MP2" ENSG00000147588 "Peripheral myelin protein 2" P02689 8 81440326-81447439 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "brain: 278.7;choroid plexus: 97.2" "Group enriched" "Detected in some" 16 "Astrocytes: 84.9;Muller glia cells: 48.5;Oligodendrocyte precursor cells: 88.4;Oligodendrocytes: 90.3" "Cancer enriched" "Detected in some" 59 "glioma: 239.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "WM-115: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 9 "spinal cord: 1313.6" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.87e-2)" "unprognostic (5.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (8.03e-3)" "unprognostic (1.10e-2)" "unprognostic (8.45e-2)" "unprognostic (4.43e-2)" "unprognostic (7.21e-2)" "unprognostic (4.41e-1)" "unprognostic (3.27e-3)" 1.8 1.4 155.1 1.4 168.0 0.0 0.7 231.4 193.1 1.3 97.2 1.4 0.4 0.1 1.8 0.8 0.3 1.1 2.0 146.1 206.4 0.4 0.2 0.1 0.0 278.7 243.1 0.2 0.4 0.0 0.7 0.0 257.4 1.8 0.7 0.2 1.0 3.7 0.3 0.3 0.6 0.3 247.1 0.0 0.6 0.1 214.0 0.0 0.3 0.8 0.0 0.9 1.1 275.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.1 168.0 231.4 193.1 146.1 206.4 278.7 243.1 257.4 247.1 214.0 275.2 1.4 0.0 0.0 84.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 4.7 0.0 48.5 0.0 88.4 90.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 PNMA8B "KIAA1183, PNMAL2" ENSG00000204851 "PNMA family member 8B" Q9ULN7 19 46486906-46495879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 14.7;brain: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 8.3;Granulosa cells: 5.3;Theca cells: 12.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.4;AN3-CA: 1.8;SH-SY5Y: 1.4" "Low region specificity" "Detected in all" HPA054810 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" "HPA054810: AB_2682609" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (3.38e-3)" "unprognostic (2.90e-1)" "unprognostic (1.35e-1)" "unprognostic (4.15e-1)" "unprognostic (4.19e-3)" "unprognostic (4.26e-4)" "unprognostic (7.30e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (3.38e-1)" "unprognostic (1.32e-2)" 2.7 14.7 32.8 0.3 31.1 0.0 2.4 0.0 41.6 1.9 0.0 1.5 0.3 1.7 0.5 0.5 1.6 1.0 1.9 20.1 25.3 0.7 0.4 0.7 0.4 22.5 15.0 3.9 0.9 0.2 7.3 0.3 27.3 1.6 0.1 2.1 1.5 1.0 0.5 2.3 0.9 0.6 2.1 1.9 0.9 0.8 18.5 3.5 0.8 0.4 0.1 1.1 1.6 19.0 0.0 0.0 1.4 1.8 0.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 31.1 0.0 41.6 20.1 25.3 22.5 15.0 27.3 2.1 18.5 19.0 8.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.9 0.3 0.0 0.5 0.9 0.8 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.1 0.0 5.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.4 0.0 0.0 PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 13.4;Bipolar cells: 38.7;Leydig cells: 18.3;Peritubular cells: 38.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 6.6;HSkMC: 11.6;hTERT-RPE1: 18.8;SiHa: 9.7;U-2 OS: 6.7" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 18.9" HPA042807 Approved "Secreted - unknown location" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" 1.8 0.7 1.9 0.9 1.7 0.5 4.9 2.3 1.8 5.6 0.8 2.8 0.4 1.5 0.2 8.2 2.1 1.3 4.7 1.2 3.6 1.7 0.5 5.1 0.2 4.3 4.4 3.3 1.5 0.1 5.1 3.7 3.0 7.9 0.3 2.0 5.3 0.9 1.6 11.4 2.3 0.5 3.1 1.0 1.7 7.2 3.7 0.0 3.1 1.3 0.2 2.7 12.0 2.0 0.3 0.4 0.4 0.2 0.6 1.5 0.1 4.1 2.4 0.8 1.6 0.3 0.4 0.2 0.3 6.6 0.2 1.6 0.1 0.1 0.4 1.5 0.6 0.8 0.4 0.0 5.1 0.2 0.5 11.6 0.7 1.1 0.1 18.8 0.0 0.1 0.4 0.3 1.6 2.7 0.2 0.2 0.1 0.3 0.4 0.1 0.1 0.0 0.3 0.0 0.7 0.4 9.7 0.1 0.3 0.4 0.1 0.5 0.7 2.0 6.7 0.5 0.2 0.3 0.0 0.1 0.8 0.9 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.9 1.7 2.3 1.8 1.2 3.6 4.3 4.4 3.0 3.1 3.7 2.0 1.4 0.0 0.5 2.3 0.0 1.3 0.9 13.4 0.0 38.7 2.1 8.0 1.6 0.0 1.4 0.0 2.1 0.4 0.2 1.8 0.0 0.2 1.7 0.5 6.1 0.9 0.0 2.7 0.5 0.0 0.2 4.7 0.0 0.4 0.0 0.5 0.7 0.1 9.8 1.7 0.7 1.1 0.0 1.2 1.7 2.1 18.3 0.9 1.8 1.9 0.0 1.8 0.0 1.5 0.3 0.6 9.0 38.0 0.0 0.5 0.6 0.1 1.4 4.6 0.0 0.6 1.0 1.0 0.7 2.6 4.3 0.8 0.2 0.1 1.4 1.6 PODXL2 "endoglycan, PODLX2" ENSG00000114631 "Podocalyxin like 2" Q9NZ53 3 127629185-127672802 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.6;pituitary gland: 59.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 96.3;Early spermatids: 73.5;Horizontal cells: 82.4;Late spermatids: 153.1;Spermatogonia: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPMI-8226: 118.1;SCLC-21H: 167.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024934, HPA042265" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "CAB024934: , HPA042265: AB_2677920" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (7.02e-2)" "unprognostic (1.07e-2)" "unprognostic (9.74e-2)" "unprognostic (1.79e-2)" "unprognostic (8.97e-3)" "unprognostic (1.81e-1)" "unprognostic (3.89e-1)" "unprognostic (2.67e-1)" "unprognostic (4.05e-3)" "unprognostic (3.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.67e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-3)" 3.8 17.3 45.0 2.7 39.9 1.8 8.8 34.1 50.9 2.9 1.9 9.4 7.2 4.4 2.3 4.2 4.3 4.5 4.1 42.3 65.6 7.2 1.6 2.0 2.2 49.2 50.9 11.2 13.5 5.3 59.0 1.0 54.6 13.1 8.2 21.6 24.9 2.0 3.2 7.6 6.7 1.8 32.9 2.0 14.1 30.8 53.6 1.9 5.5 1.8 2.7 3.1 2.8 40.5 0.3 13.8 37.5 89.2 0.0 0.0 55.2 4.3 0.2 7.9 1.6 28.7 1.5 34.0 33.3 0.6 12.1 0.2 30.9 0.0 0.7 0.2 63.3 0.7 30.9 29.3 1.2 78.1 75.7 1.5 6.6 0.2 0.0 20.9 2.2 0.2 45.6 0.2 2.9 17.6 0.3 0.3 56.2 7.9 66.6 0.2 1.0 118.1 10.9 3.9 167.0 94.0 40.9 86.3 77.2 3.7 22.0 39.2 0.4 0.2 17.2 1.5 27.3 0.2 0.0 26.9 0.9 50.1 25.1 0.0 0.0 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.6 0.5 0.1 45.0 39.9 34.1 50.9 42.3 65.6 49.2 50.9 54.6 32.9 53.6 40.5 1.6 0.0 1.1 10.4 3.4 5.5 3.7 1.3 9.1 96.3 17.5 18.4 0.5 4.3 1.7 9.2 31.3 2.2 4.4 14.3 1.9 6.8 73.5 8.7 2.5 2.2 63.5 5.5 21.3 20.1 5.9 8.2 25.0 12.3 1.3 9.5 0.7 0.7 1.3 82.4 57.7 23.2 4.1 1.3 2.8 153.1 8.7 1.6 21.4 5.6 8.1 19.0 6.2 29.1 12.5 12.9 16.7 5.7 10.4 9.9 10.8 2.9 1.7 49.9 6.6 3.8 9.8 20.4 80.4 10.0 5.5 1.5 3.3 7.5 21.8 3.1 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.5;Late spermatids: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 280.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013" Enhanced Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB011616: AB_731977, HPA049104: AB_2680632, HPA069013: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.65e-4)" 12.4 17.5 26.6 13.5 27.4 51.3 27.4 82.3 35.5 18.9 24.3 12.3 10.8 12.9 19.7 26.5 13.2 17.4 26.1 28.1 29.0 18.0 33.9 14.2 20.2 27.1 27.8 20.4 16.9 18.8 26.7 11.1 28.9 24.8 13.2 18.0 30.3 11.3 85.3 23.1 10.8 10.6 27.6 17.2 14.0 53.1 30.2 24.8 14.2 70.0 22.2 30.8 18.9 28.9 40.2 23.5 40.6 80.4 21.8 20.7 33.8 25.2 29.3 41.5 37.7 33.1 46.0 36.4 31.1 16.5 43.4 20.0 34.1 29.5 50.3 23.8 36.7 26.5 18.2 45.3 34.1 18.6 280.6 18.8 34.4 30.1 35.4 51.8 32.1 77.2 58.4 22.4 40.3 23.6 78.0 52.6 54.4 48.4 26.7 44.2 40.8 31.4 78.4 32.1 22.7 41.8 29.9 19.9 79.0 41.4 52.5 31.5 17.8 19.1 27.0 48.8 24.6 32.5 58.4 52.2 19.3 39.4 52.2 47.6 15.1 48.1 12.0 18.8 13.3 12.2 12.5 13.0 15.7 11.1 14.1 13.3 63.6 22.2 26.3 84.9 19.3 11.5 26.6 27.4 82.3 35.5 28.1 29.0 27.1 27.8 28.9 27.6 30.2 28.9 13.9 3.2 13.6 6.8 20.2 16.8 30.1 14.2 31.3 2.9 14.3 15.1 21.6 7.2 20.7 7.3 8.4 7.5 51.9 3.1 5.9 11.7 254.5 13.8 7.7 12.5 6.0 7.6 15.8 9.6 7.0 9.7 10.2 9.9 23.4 12.7 8.6 12.7 7.4 6.7 20.3 5.4 4.1 5.7 9.9 133.9 7.2 18.2 7.2 19.7 11.2 8.3 13.4 12.5 16.7 33.6 5.8 3.8 21.9 41.6 4.3 6.8 16.4 4.4 0.0 6.6 12.3 19.4 15.4 27.3 20.0 11.1 16.2 7.8 6.6 31.6 PPP1R3G ENSG00000219607 "Protein phosphatase 1 regulatory subunit 3G" B7ZBB8 6 5085341-5089487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.9;liver: 6.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 18.5;Glandular and luminal cells: 7.2" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.3;PC-3: 3.9;THP-1: 14.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056393 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA056393: AB_2683115" "unprognostic (1.99e-2)" "unprognostic (5.50e-3)" "unprognostic (2.10e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (6.56e-3)" "unprognostic (8.64e-3)" "unprognostic (1.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.04e-2)" "unprognostic (3.71e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-2)" "unprognostic (5.56e-2)" "unprognostic (3.17e-3)" "unprognostic (1.27e-1)" 2.3 3.0 2.3 0.3 2.1 0.1 1.4 1.5 2.7 2.1 0.9 2.0 0.2 1.2 1.0 1.8 1.0 0.3 5.9 2.0 1.8 0.6 6.2 0.3 0.5 2.3 2.3 0.8 0.1 0.3 0.2 0.7 1.9 1.2 0.5 0.2 0.6 1.4 0.5 1.2 0.5 0.5 1.6 2.8 0.6 0.2 2.2 0.2 0.3 0.2 0.4 2.8 2.1 1.7 0.0 0.2 0.1 0.0 1.6 1.0 0.0 0.3 0.4 0.2 0.3 0.0 0.3 0.0 3.3 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.3 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 3.9 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.5 0.0 0.0 0.3 0.0 14.6 0.0 0.0 0.0 0.8 0.5 2.0 1.7 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 2.3 2.1 1.5 2.7 2.0 1.8 2.3 2.3 1.9 1.6 2.2 1.7 4.2 0.0 0.0 0.0 0.4 0.5 0.5 0.4 0.0 0.5 0.2 0.1 18.5 0.0 0.1 3.7 0.0 0.8 0.0 1.3 0.0 0.3 0.0 1.2 2.0 1.9 1.2 0.0 0.0 0.0 0.4 3.7 0.0 7.2 0.0 1.4 2.9 0.0 4.5 0.0 0.0 0.9 0.0 4.0 4.7 0.2 0.9 1.8 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.6 1.8 3.0 1.8 0.4 0.0 2.1 0.2 0.2 0.0 2.0 2.5 0.1 0.9 0.2 0.3 0.8 0.2 0.5 1.4 1.2 PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8;Excitatory neurons: 307.7;Inhibitory neurons: 122.2;Microglial cells: 64.6;Oligodendrocyte precursor cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.6;naive B-cell: 11.5" "Lineage enriched" "Detected in many" 4 "B-cells: 11.5" "Cell line enriched" "Detected in many" 18 "HBEC3-KT: 1015.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001379, HPA050037" Approved Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA001379: AB_1855703, HPA050037: " "unprognostic (2.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.22e-1)" "unprognostic (2.34e-4)" "unprognostic (3.53e-1)" "unprognostic (1.69e-2)" "unprognostic (5.89e-2)" "unprognostic (5.29e-2)" "unprognostic (7.77e-2)" "unprognostic (1.21e-3)" "unprognostic (2.29e-4)" "unprognostic (1.12e-1)" "unprognostic (8.95e-3)" "unprognostic (5.33e-4)" 6.3 3.0 3.7 5.2 5.0 1.7 5.0 0.0 7.2 12.5 0.0 4.2 2.6 12.1 1.6 2.4 6.4 10.0 13.8 4.2 0.0 5.0 1.7 9.5 4.6 0.1 1.3 12.5 2.0 1.4 2.0 5.3 0.0 5.1 2.2 4.2 7.8 5.6 3.9 4.7 2.4 12.7 0.0 14.8 2.9 6.0 3.9 1.6 7.9 4.6 3.4 5.5 6.3 1.0 7.7 4.4 17.0 0.5 12.4 13.1 0.5 11.0 5.2 3.0 5.1 0.5 16.0 0.5 31.4 1.6 0.0 2.9 12.5 1015.4 3.5 0.6 6.4 17.5 0.9 0.4 1.7 0.3 0.2 19.3 7.5 12.7 1.7 1.8 39.7 0.3 1.8 3.1 2.9 0.3 0.1 0.5 56.1 0.1 18.0 0.2 0.7 0.1 21.1 0.7 4.4 3.0 0.3 0.7 0.7 13.7 0.3 35.1 2.9 0.9 13.4 14.0 14.2 0.9 0.6 6.1 0.2 10.7 0.6 2.6 1.8 0.4 0.2 1.0 0.7 7.6 0.2 0.2 1.0 11.5 0.4 0.2 2.4 0.5 0.6 1.6 0.2 0.9 3.7 5.0 0.0 7.2 4.2 0.0 0.1 1.3 0.0 0.0 3.9 1.0 6.9 16.0 8.2 8.8 13.2 2.7 5.3 7.3 4.0 13.5 4.0 2.2 5.7 14.3 2.6 1.8 2.1 0.6 0.2 0.0 0.0 3.8 72.8 5.2 43.0 8.1 0.0 0.4 307.7 2.6 0.2 19.2 3.6 8.6 1.3 59.1 14.6 0.1 0.6 8.4 122.2 0.0 2.0 0.9 2.3 25.4 9.9 1.2 7.2 64.6 1.1 2.7 0.0 114.6 5.3 3.9 0.1 24.8 3.1 1.0 0.0 3.3 0.3 4.5 0.0 3.8 7.9 5.1 4.8 1.9 1.4 0.7 1.1 18.6 0.0 0.8 PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 778.3;Excitatory neurons: 244.9;Inhibitory neurons: 473.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "AN3-CA: 14.3;BJ hTERT+: 19.2;fHDF/TERT166: 16.1;U-138 MG: 11.2;U-87 MG: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 7.0 8.3 6.4 2.7 7.2 0.6 3.1 1.4 6.9 10.3 12.4 5.5 2.4 10.3 3.5 5.2 5.2 7.0 14.1 6.6 10.7 3.8 1.7 6.8 1.2 5.1 4.6 4.2 1.7 9.6 1.3 10.1 3.2 6.4 5.3 3.6 4.0 8.1 25.8 1.0 3.4 14.6 5.3 2.5 3.3 1.8 12.2 1.5 7.0 36.1 0.9 5.4 4.2 2.7 0.1 0.2 1.7 14.3 6.5 6.0 0.1 5.4 19.2 2.1 2.6 0.1 0.9 0.3 0.0 16.1 2.0 0.1 0.0 0.1 1.7 0.0 5.0 1.0 0.3 0.0 5.5 0.0 0.1 8.1 0.1 4.8 0.1 0.6 0.0 0.0 0.0 0.1 5.3 0.1 0.0 0.0 4.1 0.0 2.5 0.0 3.9 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 2.0 0.1 0.0 0.0 11.2 1.9 5.9 3.7 1.5 0.8 0.0 10.0 0.0 2.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.4 7.2 1.4 6.9 6.6 10.7 5.1 4.6 3.2 5.3 12.2 2.7 10.5 16.0 10.8 778.3 0.3 0.9 1.7 0.0 7.4 5.9 2.8 9.4 31.4 0.0 0.0 3.7 0.0 1.0 0.3 2.9 0.0 2.4 56.0 0.4 14.7 7.1 0.0 3.4 244.9 3.6 1.2 24.2 0.5 0.5 4.5 0.1 5.0 0.0 0.4 0.0 473.0 4.2 0.0 0.0 2.2 53.0 32.6 5.3 3.6 188.3 0.0 23.6 0.0 24.6 8.0 4.8 14.1 39.5 0.1 0.5 3.2 0.2 0.9 1.3 39.5 3.9 69.9 0.9 0.9 1.6 0.6 2.2 0.2 7.9 3.6 1.0 PROX1 ENSG00000117707 "Prospero homeobox 1" Q92786 1 213983181-214041510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2;liver: 86.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 196.4;Hepatocytes: 285.9;Horizontal cells: 523.3;Paneth cells: 130.6" "Cancer enhanced" "Detected in many" "liver cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 31.4;RH-30: 15.9;SH-SY5Y: 77.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000842, HPA001030, HPA027298" Enhanced Nucleoplasm,Cytosol No No "Cluster 43: B-cells - Humoral immune response" "Cluster 15: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA000842: AB_2666112, HPA001030: AB_2666177, HPA027298: " "unprognostic (3.07e-1)" "unprognostic (5.98e-2)" "unprognostic (1.06e-3)" "unprognostic (3.42e-1)" "unprognostic (7.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (6.59e-2)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (3.29e-3)" "unprognostic (6.64e-2)" "unprognostic (4.56e-6)" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (6.71e-4)" "unprognostic (1.05e-1)" 1.6 10.0 11.0 1.4 21.4 0.0 1.8 24.6 18.2 1.0 0.0 2.6 2.1 1.1 1.2 0.6 2.2 1.9 15.7 23.1 12.4 4.7 86.8 1.2 2.8 18.7 17.3 7.4 15.5 0.1 4.0 0.4 13.9 0.5 2.7 21.2 0.3 0.4 3.6 0.7 2.6 0.8 10.6 7.1 2.1 5.4 30.0 0.2 7.6 2.1 0.7 1.0 0.7 38.2 0.0 0.0 0.6 0.0 0.3 0.3 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.0 0.3 0.2 2.3 0.0 0.1 0.0 1.0 0.6 0.0 31.4 0.0 0.0 0.2 0.3 0.1 0.0 0.2 0.1 3.5 2.3 5.7 0.0 0.4 0.0 0.4 0.0 1.7 2.0 1.3 0.0 15.9 2.5 0.2 0.5 2.3 77.2 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.2 0.7 0.2 0.9 0.0 0.0 0.0 0.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 21.4 24.6 18.2 23.1 12.4 18.7 17.3 13.9 10.6 30.0 38.2 14.3 0.0 2.3 1.3 1.9 5.9 1.1 0.3 5.7 196.4 4.8 4.7 105.9 102.9 1.3 9.2 2.1 0.0 0.1 3.2 15.6 34.7 52.7 0.1 1.0 36.5 66.9 5.3 2.9 2.7 0.1 8.7 8.6 0.3 0.0 9.3 11.0 285.9 0.9 523.3 66.8 16.5 12.2 4.4 6.6 10.4 1.2 2.2 10.6 8.4 0.0 36.0 0.0 27.2 114.0 3.4 130.6 1.2 0.1 3.9 3.3 0.4 0.9 11.7 0.0 113.6 3.7 2.9 0.4 0.4 4.5 0.0 1.9 29.6 10.5 0.9 PRPH "NEF4, PRPH1" ENSG00000135406 Peripherin P41219 12 49293252-49298686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.6;intestine: 21.0" "Group enriched" "Detected in some" 6 "Early spermatids: 327.5;Late spermatids: 920.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.6;glioma: 1.7;pancreatic cancer: 1.1;testis cancer: 1.5" "Group enriched" "Detected in many" 5 "medulla oblongata: 51.9;pons: 53.6;white matter: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 367.0" "Group enriched" "Detected in many" 4 "hypothalamus: 19.4;pons and medulla: 35.1" "Region enriched" "Detected in many" 8 "spinal cord: 256.8" "CAB002437, HPA039277, HPA063887" Enhanced NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "CAB002437: AB_563956, HPA039277: AB_2676424, HPA063887: AB_2685142" "unprognostic (1.73e-2)" "unprognostic (3.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.04e-3)" "unprognostic (1.88e-2)" "unprognostic (6.29e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.38e-2)" "unprognostic (1.24e-1)" "unprognostic (4.25e-3)" "unprognostic (3.63e-2)" "unprognostic (5.73e-2)" "unprognostic (4.86e-3)" "unprognostic (6.36e-5)" 3.1 14.5 0.9 7.5 1.1 0.0 1.8 0.3 1.8 3.3 0.4 21.0 4.7 0.8 0.1 0.5 3.1 0.6 1.2 0.9 2.2 0.9 0.1 0.9 0.2 51.9 8.0 0.7 1.3 0.1 2.9 0.3 53.6 2.3 2.1 1.5 0.5 1.5 0.4 1.1 8.9 2.0 7.8 1.2 5.2 13.2 0.9 0.1 0.5 0.2 0.1 1.5 8.3 15.7 0.0 0.7 0.0 367.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.7 1.6 0.4 1.3 0.2 0.2 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.7 0.0 0.2 2.0 0.0 2.2 0.4 0.0 1.6 86.6 1.5 0.2 0.8 0.0 0.0 1.7 0.1 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.3 1.8 0.9 2.2 51.9 8.0 53.6 7.8 0.9 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 10.8 0.3 0.8 0.4 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 327.5 0.5 0.1 1.4 92.3 0.0 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 25.2 0.1 1.0 0.0 0.0 0.9 920.2 5.9 0.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.8 0.1 38.1 0.0 0.1 14.1 96.1 19.4 0.3 0.4 0.0 0.1 0.0 0.5 0.2 PRRT1 "C6orf31, DSPD1, IFITMD7, NG5" ENSG00000204314 "Proline rich transmembrane protein 1" Q99946 6 32148359-32153083 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 40.1;ovary: 11.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 67.5;Cardiomyocytes: 125.5;Granulosa cells: 181.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 38.4;cerebral cortex: 40.1;hippocampal formation: 37.0;white matter: 17.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.0;SK-MEL-30: 1.6;U-2 OS: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055149, HPA059099" Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "HPA055149: AB_2682717, HPA059099: AB_2732632" "unprognostic (1.40e-2)" "unprognostic (1.35e-1)" "unprognostic (2.10e-3)" "unprognostic (3.87e-3)" "unprognostic (2.89e-1)" "unprognostic (4.74e-2)" "unprognostic (5.51e-3)" "unprognostic (5.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (8.08e-5)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (9.40e-2)" "unprognostic (1.94e-1)" "unprognostic (1.78e-2)" 1.6 2.2 38.4 0.3 6.4 0.0 2.0 0.0 40.1 2.7 0.0 2.9 0.6 2.3 0.0 1.5 3.6 0.1 1.6 37.0 4.8 3.1 0.9 1.3 0.1 3.4 2.1 11.9 0.6 0.3 5.6 0.2 2.2 3.1 0.0 1.3 0.9 0.6 0.4 2.0 1.8 0.0 0.0 0.9 2.0 1.3 6.5 0.0 1.9 0.0 0.0 2.4 2.4 17.5 0.0 0.1 0.0 0.5 0.2 0.1 0.2 0.8 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.8 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.4 6.4 0.0 40.1 37.0 4.8 3.4 2.1 2.2 0.0 6.5 17.5 3.2 0.0 0.0 4.9 0.5 4.0 8.0 3.4 14.8 67.5 1.8 3.0 125.5 10.0 1.2 1.8 10.4 6.7 1.7 2.2 1.9 0.1 1.3 1.3 2.3 6.7 9.0 4.2 12.6 0.0 1.0 7.8 4.6 0.5 0.0 181.6 5.0 3.5 1.0 32.0 10.9 5.5 0.0 0.8 2.1 1.2 6.2 1.9 3.6 6.5 0.2 16.0 1.0 3.5 5.0 0.2 3.4 6.4 0.8 3.6 5.5 0.1 3.7 8.7 0.0 3.6 8.0 0.8 1.6 3.8 2.7 3.6 2.2 8.1 4.1 4.8 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PRRX1 "PHOX1, PMX1" ENSG00000116132 "Paired related homeobox 1" P54821 1 170662728-170739421 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 351.7;Endometrial stromal cells: 158.6;Fibroblasts: 180.2;Late spermatids: 390.0;Leydig cells: 256.3;Oligodendrocyte precursor cells: 288.5;Smooth muscle cells: 206.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 367.0;ASC TERT1: 290.5;BJ: 109.7;BJ hTERT+: 213.2;HSkMC: 150.6;U-138 MG: 146.0;U-2197: 140.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051084, HPA063566" Uncertain Supported Nucleoplasm NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA051084: AB_2681338, HPA063566: AB_2732702" "unprognostic (2.03e-1)" "unprognostic (2.00e-1)" "unprognostic (1.09e-1)" "unprognostic (7.00e-2)" "unprognostic (1.24e-1)" "unprognostic (4.97e-2)" "unprognostic (2.52e-2)" "unprognostic (1.88e-2)" "unprognostic (2.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.60e-10)" "unprognostic (4.23e-3)" "unprognostic (4.48e-2)" "unprognostic (2.68e-3)" "unprognostic (1.69e-3)" 96.3 10.2 14.5 17.7 15.2 0.0 42.9 15.4 13.4 92.0 5.4 5.6 1.1 68.6 20.3 20.1 42.3 34.1 44.2 12.6 26.2 2.3 0.4 21.7 34.6 17.4 18.5 28.2 3.8 7.5 4.9 6.3 16.8 33.5 5.7 0.1 38.5 75.6 51.7 24.1 3.6 52.4 7.9 1.9 3.4 14.2 16.5 18.7 41.6 73.9 36.3 33.0 58.8 15.0 0.0 0.0 2.1 0.0 367.0 290.5 0.1 109.7 213.2 15.0 14.8 0.0 0.1 0.1 0.0 90.2 0.0 0.0 18.5 0.0 4.7 0.0 0.2 0.0 1.6 0.0 1.2 0.0 0.0 150.6 0.0 73.4 0.4 25.7 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.8 0.0 0.0 0.1 146.0 2.6 140.4 16.9 0.0 0.0 0.0 77.3 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 15.2 15.4 13.4 12.6 26.2 17.4 18.5 16.8 7.9 16.5 15.0 49.8 0.0 0.5 114.3 0.3 16.3 0.6 0.1 4.0 0.0 1.3 10.2 29.8 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.2 351.7 4.9 158.6 11.4 0.0 0.0 17.4 0.2 0.1 180.2 0.5 3.5 0.0 0.6 0.0 0.0 0.8 0.0 5.5 0.0 0.0 0.0 27.9 390.0 256.3 2.8 14.2 124.6 0.0 0.5 0.0 288.5 0.9 0.7 0.0 104.6 0.4 1.7 0.0 0.1 0.0 0.2 52.6 59.1 206.5 15.4 1.9 1.2 11.8 0.1 2.3 0.6 0.0 1.2 PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 50.5" "Cell type enriched" "Detected in some" 36 "Muller glia cells: 410.9" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 195 "T-cells: 19.5" "Cell line enhanced" "Detected in some" "BJ hTERT+: 10.4;CACO-2: 86.3;HAP1: 12.8;RPTEC TERT1: 24.6;SuSa: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 2.9;cerebellum: 3.6;cerebral cortex: 5.8;hippocampal formation: 5.3;olfactory bulb: 2.7" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" 1.3 2.4 2.9 0.1 3.8 0.0 0.3 1.7 6.8 2.9 1.5 0.1 0.3 1.3 1.1 0.3 1.4 4.2 4.4 3.2 2.1 3.1 0.4 1.3 0.7 1.8 1.9 10.2 0.3 0.3 1.1 3.6 1.8 1.1 0.3 50.5 0.3 0.4 0.1 0.2 0.1 1.5 1.8 0.7 0.3 3.1 2.6 0.1 0.4 0.1 0.1 1.3 0.5 2.2 0.0 0.5 1.9 0.0 0.1 0.0 0.0 0.3 10.4 1.0 2.0 86.3 0.0 0.0 0.1 0.4 0.0 0.0 12.8 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 3.1 0.0 1.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 0.4 8.2 0.0 0.0 0.0 24.6 0.0 0.0 1.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 19.5 0.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 3.8 1.7 6.8 3.2 2.1 1.8 1.9 1.8 1.8 2.6 2.2 0.3 3.2 0.5 8.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 1.5 0.0 0.0 1.8 0.0 0.3 0.0 0.1 9.8 0.1 0.1 0.0 0.3 0.8 1.8 0.0 0.2 0.0 0.0 4.4 0.0 0.0 0.0 0.9 0.0 0.3 0.4 6.7 0.2 0.0 0.0 0.0 0.0 0.2 1.2 0.1 0.0 1.0 0.0 410.9 0.0 1.0 0.1 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 11.4 6.6 0.1 3.7 0.1 0.5 0.0 0.0 0.1 0.7 5.1 0.0 0.0 PRTFDC1 HHGP ENSG00000099256 "Phosphoribosyl transferase domain containing 1" Q9NRG1 10 24848614-24952606 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 136.1;Oligodendrocyte precursor cells: 111.6;Oligodendrocytes: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 4.4" "Lineage enriched" "Detected in single" 8 "NK-cells: 4.4" "Cell line enhanced" "Detected in many" "CACO-2: 75.9;CAPAN-2: 94.3;HEL: 56.2" "Low region specificity" "Detected in all" HPA021458 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Golgi apparatus, Cytosol" "HPA021458: AB_1855793" "unprognostic (2.61e-1)" "unprognostic (3.47e-1)" "unprognostic (3.69e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (9.49e-3)" "unprognostic (2.03e-1)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (2.36e-1)" "unprognostic (3.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.25e-2)" "unprognostic (2.50e-1)" "unprognostic (7.66e-3)" "unprognostic (1.94e-2)" 5.4 22.2 21.7 4.5 28.7 0.9 7.6 24.9 27.2 12.9 16.1 9.9 17.7 15.8 7.4 5.5 9.8 14.8 10.9 22.4 24.6 4.8 2.8 4.3 4.2 26.7 24.0 20.2 4.6 13.4 11.4 2.9 28.0 7.8 11.3 16.5 9.7 8.2 1.3 1.8 17.1 9.8 25.8 3.2 17.5 2.2 23.7 6.8 5.3 2.8 3.2 7.4 6.3 37.1 19.5 41.3 30.2 12.4 4.9 24.4 0.0 20.2 15.1 14.2 19.3 75.9 94.3 0.0 3.1 23.7 1.2 10.7 34.7 0.0 22.0 0.0 1.4 56.2 7.6 0.1 14.6 0.0 0.0 7.1 0.2 7.7 0.0 13.3 22.6 2.2 18.6 10.5 6.8 0.5 8.8 0.1 20.9 3.3 0.7 9.7 0.1 0.2 12.7 0.5 21.5 0.9 19.3 0.1 0.0 0.6 1.1 4.3 12.2 6.3 15.5 23.1 12.2 0.9 0.0 0.0 16.8 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.2 0.0 4.4 0.0 0.1 0.0 0.9 21.7 28.7 24.9 27.2 22.4 24.6 26.7 24.0 28.0 25.8 23.7 37.1 3.5 0.0 0.5 136.1 0.7 2.7 4.6 5.4 2.8 10.2 1.1 5.8 8.6 7.2 3.9 3.7 2.1 1.0 0.8 3.8 5.9 5.8 1.4 1.5 27.3 2.8 5.4 3.0 38.2 0.5 4.9 20.6 12.2 2.2 0.0 25.1 7.5 0.1 7.2 6.7 43.0 7.3 0.0 0.9 3.1 1.0 12.2 7.8 3.6 24.4 1.5 45.8 0.0 111.6 148.2 2.3 2.1 9.8 1.3 1.1 12.2 0.1 1.1 15.9 0.0 16.4 10.4 3.4 6.3 0.4 2.8 0.8 1.0 22.7 11.6 1.5 PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.2;Cardiomyocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 146.8;WM-115: 111.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" 11.6 21.1 3.2 10.1 3.5 0.0 10.6 3.3 4.8 14.9 8.3 40.6 11.3 31.2 10.6 21.2 23.9 17.2 48.8 3.3 2.6 4.0 6.6 6.6 2.5 2.8 4.5 15.9 13.3 6.3 2.9 5.0 2.2 18.0 21.7 1.4 18.5 23.6 2.9 17.8 14.0 46.6 4.6 3.1 10.5 5.3 4.1 5.3 6.9 3.9 6.2 20.1 15.1 3.2 40.0 10.3 18.4 42.8 3.2 8.3 2.6 2.8 4.4 15.4 5.8 7.2 8.7 0.0 35.7 10.6 12.7 69.7 41.4 74.4 9.7 0.4 25.1 2.9 24.0 11.1 1.1 0.1 3.9 37.3 66.0 2.0 36.4 21.9 30.0 4.2 16.5 0.2 23.5 50.9 0.0 5.5 21.5 3.3 0.1 0.0 100.6 0.2 51.3 32.4 9.0 20.8 80.0 55.9 22.9 32.1 48.8 12.3 77.6 22.4 33.2 37.2 25.1 0.0 0.1 0.1 146.8 0.0 111.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.5 3.3 4.8 3.3 2.6 2.8 4.5 2.2 4.6 4.1 3.2 2.3 3.2 5.9 15.0 0.5 66.2 13.4 25.6 22.2 6.5 10.9 11.9 79.4 10.0 12.2 3.7 0.0 0.8 0.3 20.6 1.9 31.2 4.8 10.2 19.3 12.1 13.9 0.0 13.6 31.8 5.5 32.0 10.7 16.9 0.0 22.1 3.9 11.1 4.4 0.0 7.4 18.2 14.2 8.8 9.7 6.3 19.3 4.7 8.8 3.7 3.1 1.2 0.0 31.2 0.9 27.9 11.1 30.1 0.0 15.1 15.8 1.2 13.6 0.2 19.7 48.5 12.5 0.8 5.2 20.3 45.3 0.8 1.4 28.3 26.3 17.4 PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 22.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 254.0;Basal squamous epithelial cells: 93.9;Breast glandular cells: 105.4;Breast myoepithelial cells: 56.3;Club cells: 77.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HaCaT: 291.3;HBEC3-KT: 359.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" 3.1 0.8 1.8 1.2 2.3 0.0 20.1 0.6 3.2 13.6 10.2 3.3 2.3 10.7 1.1 16.2 1.5 7.5 4.2 4.1 3.2 0.4 0.2 1.2 1.1 4.0 8.1 1.8 1.7 22.8 2.9 3.0 0.4 5.2 1.6 0.2 8.5 2.4 0.7 2.0 1.6 3.0 0.2 3.6 1.8 1.3 8.6 0.4 1.8 1.7 1.0 9.2 15.2 0.8 1.7 9.9 0.0 0.0 2.9 2.8 0.1 0.3 1.0 0.5 1.3 0.3 7.9 0.0 0.5 2.6 9.1 291.3 1.3 359.8 0.1 7.4 1.7 0.5 1.8 0.1 0.8 0.1 0.4 0.2 19.7 9.1 34.4 0.9 11.2 0.1 0.0 0.4 0.2 0.1 0.1 0.0 1.4 0.4 16.7 0.1 1.5 0.6 34.3 0.3 0.2 0.1 16.4 0.1 2.1 11.5 0.5 0.1 5.6 1.6 8.9 5.1 77.8 4.7 0.1 12.1 7.5 0.2 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.8 2.3 0.6 3.2 4.1 3.2 4.0 8.1 0.4 0.2 8.6 0.8 1.4 0.0 0.0 0.7 0.4 4.6 1.9 254.0 93.9 0.3 105.4 56.3 0.4 0.0 77.5 0.0 0.0 0.0 0.5 0.0 0.0 3.5 5.9 0.9 4.7 4.5 0.0 0.0 0.6 8.9 0.0 13.6 0.0 0.8 0.0 2.6 0.4 0.2 0.0 0.0 11.2 0.0 4.1 0.3 1.3 2.7 0.9 0.6 23.2 1.0 0.6 1.8 0.0 0.0 0.2 8.6 0.0 0.0 6.2 0.5 0.0 0.3 14.8 0.5 6.6 8.0 6.7 3.6 0.2 7.9 1.4 0.0 0.5 0.2 0.0 0.2 PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 280.4;parathyroid gland: 383.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 672.0;Extravillous trophoblasts: 416.0;Horizontal cells: 526.6;Muller glia cells: 548.5;Oligodendrocyte precursor cells: 322.7;Squamous epithelial cells: 439.9" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 12 "AF22: 1717.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" NA NA 167000 1400000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" 26.2 18.2 212.9 4.1 206.4 0.1 82.3 217.0 280.4 100.0 182.0 31.4 5.4 76.8 55.3 78.2 19.2 55.9 87.7 209.6 205.2 38.4 8.5 18.4 7.4 220.3 200.5 19.0 8.4 383.5 126.1 36.2 196.3 116.1 21.6 63.4 37.4 52.5 2.2 9.1 10.1 54.0 204.2 40.4 15.7 53.8 207.6 21.4 18.9 18.8 11.4 24.8 65.1 209.1 1.2 0.0 1717.6 21.2 0.4 0.9 140.6 45.3 134.3 25.1 34.3 0.4 0.2 0.0 0.2 60.0 15.6 1.0 0.0 0.0 18.9 0.0 1.4 0.0 0.0 0.0 7.7 0.0 0.5 1.9 0.0 16.6 0.2 24.6 0.0 0.0 0.0 8.2 7.0 0.0 0.0 0.6 133.5 0.0 1.1 0.1 2.8 0.4 0.7 0.0 8.0 116.5 0.0 0.0 0.2 24.1 0.2 0.2 0.0 37.4 32.9 1.8 99.4 0.7 0.0 0.0 119.7 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 212.9 206.4 217.0 280.4 209.6 205.2 220.3 200.5 196.3 204.2 207.6 209.1 10.1 0.0 0.0 303.3 1.3 23.2 1.7 85.0 209.5 27.7 244.6 117.3 14.6 2.8 20.9 1.8 6.2 220.0 2.2 0.0 9.8 1.1 24.5 53.4 672.0 32.0 0.0 0.0 4.9 0.0 416.0 248.8 0.5 24.6 0.0 1.1 7.1 0.3 20.4 526.6 18.1 0.0 0.0 0.3 20.6 14.0 172.7 4.0 44.4 102.1 0.0 548.5 0.0 322.7 218.4 0.3 0.0 185.5 2.5 18.6 0.0 7.5 7.2 32.3 59.2 3.0 91.4 4.0 2.4 439.9 13.9 193.3 4.4 144.7 0.0 2.2 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RARG "NR1B3, RARC" ENSG00000172819 "Retinoic acid receptor gamma" P13631 12 53210567-53232980 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.6;skin 1: 121.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.7;Squamous epithelial cells: 69.9;Suprabasal keratinocytes: 55.8;Urothelial cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.8" "Group enriched" "Detected in all" 4 "dendritic cells: 6.7;T-cells: 18.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 101.0;MCF7: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053883 Supported Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA053883: AB_2682292" "unprognostic (7.29e-2)" "unprognostic (1.95e-2)" "unprognostic (6.11e-2)" "prognostic unfavorable (3.68e-6)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" "unprognostic (2.28e-1)" "unprognostic (1.08e-2)" "unprognostic (3.54e-3)" "unprognostic (7.21e-3)" "unprognostic (3.78e-3)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (5.41e-3)" "unprognostic (1.98e-2)" "unprognostic (5.94e-3)" "unprognostic (7.41e-2)" 17.4 16.2 10.2 5.7 9.7 3.7 19.4 13.0 10.9 55.0 10.8 22.7 2.5 23.3 6.0 141.6 27.2 15.7 17.3 9.7 9.5 12.5 3.2 15.2 5.9 10.3 10.0 20.5 8.5 7.2 8.7 9.5 9.3 26.9 7.8 3.9 30.6 16.2 6.9 121.4 10.4 13.0 10.0 10.2 14.5 4.8 9.5 5.1 22.6 10.6 22.5 26.2 69.3 10.0 22.8 24.7 5.5 50.9 55.0 46.8 1.7 23.2 50.0 29.7 23.3 8.3 101.0 0.5 12.5 93.6 16.2 74.3 18.4 44.6 7.4 5.7 9.4 3.3 18.6 7.4 23.2 0.0 9.1 34.8 63.9 28.5 6.4 74.7 12.7 4.6 0.8 9.8 11.9 110.3 1.3 1.1 16.3 30.4 42.7 7.3 1.9 18.1 8.9 37.1 4.4 22.9 47.0 50.6 32.1 6.8 43.9 1.4 13.8 35.4 16.5 23.6 1.5 4.2 2.6 1.8 43.4 3.8 51.3 1.8 3.1 0.9 7.4 0.9 18.8 2.0 6.5 5.4 6.7 0.6 5.2 4.7 0.0 2.3 0.0 0.6 1.8 4.0 10.2 9.7 13.0 10.9 9.7 9.5 10.3 10.0 9.3 10.0 9.5 10.0 10.7 3.2 7.0 21.2 2.5 34.2 24.1 21.6 42.7 0.5 18.0 15.6 3.7 11.5 11.1 3.7 2.1 7.5 6.2 3.2 0.0 10.5 0.1 3.6 14.4 11.0 1.8 0.8 2.5 5.1 1.2 19.6 13.7 3.4 1.3 0.3 20.3 0.1 2.7 0.0 3.0 2.1 12.2 4.1 13.3 0.5 5.3 4.9 8.8 6.5 1.8 3.6 5.2 7.1 0.7 14.3 4.4 5.3 3.0 19.2 0.2 0.5 3.9 5.2 6.6 9.5 22.0 0.8 5.6 69.9 55.8 1.8 7.2 0.4 5.5 45.7 RBP1 "CRABP-I, CRBP, CRBP1, CRBPI, RBPC" ENSG00000114115 "Retinol binding protein 1" P09455 3 139517434-139539829 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 1366.7;pancreas: 632.7" "Group enriched" "Detected in many" 4 "Granulosa cells: 5988.6;Theca cells: 3228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SH-SY5Y: 835.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 64.4" "HPA007338, CAB018603, CAB019276" Enhanced Approved Nucleoplasm,Cytosol NA NA 41000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol Nucleoplasm "CAB018603: AB_2060572, CAB019276: , HPA007338: AB_2667814" "unprognostic (9.62e-3)" "unprognostic (7.67e-2)" "unprognostic (9.53e-3)" "unprognostic (5.17e-1)" "unprognostic (7.48e-3)" "unprognostic (2.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.16e-1)" "unprognostic (7.12e-2)" "unprognostic (3.91e-3)" "unprognostic (2.74e-2)" "unprognostic (8.86e-2)" "unprognostic (1.11e-3)" "unprognostic (2.60e-2)" "unprognostic (1.71e-1)" "unprognostic (4.50e-2)" "unprognostic (1.28e-3)" 23.7 377.1 64.6 18.4 65.2 1.3 49.5 64.9 72.7 53.8 251.4 30.3 32.3 180.2 64.2 35.4 390.2 182.9 60.1 65.5 67.8 46.9 140.8 26.8 18.6 83.1 69.0 1366.7 632.7 46.8 257.8 63.6 64.7 44.8 14.2 23.2 50.2 41.3 15.2 31.3 26.2 119.3 68.2 47.0 29.3 56.1 75.2 9.4 23.0 15.5 12.0 65.7 24.3 67.5 7.8 2.9 7.4 164.2 0.3 0.0 0.9 0.1 0.0 0.0 0.1 0.4 76.1 0.0 53.8 0.1 2.6 0.1 38.2 0.5 0.0 0.1 5.3 0.1 2.7 75.5 155.1 0.2 0.1 3.0 0.0 0.1 0.0 160.9 0.0 0.0 0.2 29.9 0.2 0.0 0.2 0.5 18.4 0.2 0.0 0.1 32.0 0.5 0.1 0.1 19.6 835.4 35.3 0.1 0.1 13.9 3.2 1.1 0.0 0.3 120.0 0.2 0.3 0.6 0.5 0.5 1.3 0.0 2.3 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 64.6 65.2 64.9 72.7 65.5 67.8 83.1 69.0 64.7 68.2 75.2 67.5 24.8 32.1 5.9 8.8 3.5 17.6 53.5 91.9 2.8 26.3 70.4 47.8 21.4 77.2 30.3 23.9 2.1 3.2 1.0 0.1 13.7 1013.0 4.8 199.6 961.4 103.8 43.1 13.5 0.5 1042.7 6.2 158.8 19.9 58.1 0.0 5988.6 343.7 6.9 16.5 3.3 0.3 2.3 42.7 10.6 3.4 16.2 27.1 25.1 8.8 5.6 13.5 159.9 0.0 4.0 16.0 563.0 0.0 4.5 2.9 56.6 2.6 4.7 10.3 7.2 26.3 220.9 534.7 11.6 4.9 6.2 34.9 3.8 10.2 3228.5 2.7 32.7 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 REEP2 "C5orf19, SGC32445, SPG72, Yip2d" ENSG00000132563 "Receptor accessory protein 2" Q9BRK0 5 138439057-138446969 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.7;choroid plexus: 77.8;retina: 61.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.3;Cone photoreceptor cells: 70.9;Excitatory neurons: 51.2;Horizontal cells: 48.8;Inhibitory neurons: 46.1;Muller glia cells: 29.8;Rod photoreceptor cells: 73.6" "Cancer enriched" "Detected in many" 9 "glioma: 31.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 97.3;SCLC-21H: 40.5;SH-SY5Y: 46.1;U-87 MG: 36.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031813, HPA076571" Enhanced Supported Approved "Endoplasmic reticulum" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA031813: AB_2674054, HPA076571: " "prognostic favorable (7.83e-5)" "unprognostic (1.11e-2)" "unprognostic (3.97e-6)" "unprognostic (3.70e-3)" "prognostic unfavorable (6.65e-4)" "unprognostic (5.43e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-1)" "prognostic favorable (9.31e-4)" "unprognostic (5.93e-2)" "unprognostic (3.70e-3)" "unprognostic (9.78e-2)" "unprognostic (6.54e-3)" "unprognostic (7.54e-2)" "unprognostic (1.47e-3)" "unprognostic (6.19e-3)" "unprognostic (1.13e-3)" 4.6 9.5 106.7 2.5 102.5 0.3 3.0 93.5 155.7 3.6 77.8 18.8 1.8 7.0 1.4 4.4 3.6 2.6 24.8 110.3 110.7 1.9 0.2 0.8 0.4 134.6 109.1 4.0 2.0 1.8 54.5 0.6 136.4 8.6 2.2 61.2 1.8 8.0 16.6 2.4 4.3 12.6 77.5 0.4 7.6 6.2 130.6 1.9 1.2 5.7 0.5 8.7 4.6 104.7 0.6 7.4 27.6 97.3 3.9 10.5 0.0 8.4 3.8 11.4 12.9 5.3 1.0 0.1 1.5 10.5 0.2 0.6 26.1 5.4 8.6 3.1 23.7 0.0 1.8 12.6 9.8 0.1 0.1 3.2 0.3 6.4 0.5 19.9 2.3 27.6 0.1 6.9 3.6 4.4 2.7 1.8 17.2 0.0 0.3 9.7 2.6 0.0 2.1 0.0 40.5 46.1 2.9 0.1 7.5 7.0 2.6 0.9 0.2 6.6 6.6 6.4 15.9 18.1 12.3 0.8 36.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 106.7 102.5 93.5 155.7 110.3 110.7 134.6 109.1 136.4 77.5 130.6 104.7 17.0 0.0 0.0 18.9 0.1 0.6 1.0 1.6 2.2 47.3 0.7 3.3 9.8 0.0 0.2 1.8 70.9 0.0 0.3 0.0 0.0 0.0 1.1 0.4 0.3 5.6 4.8 0.4 51.2 0.0 0.0 3.7 0.0 0.1 0.0 1.5 0.7 0.0 0.1 48.8 46.1 0.0 0.0 0.0 0.7 5.0 0.0 0.3 0.0 2.8 0.1 29.8 0.0 19.1 5.7 0.1 0.0 2.6 1.3 0.4 3.6 0.3 0.6 73.6 0.0 7.6 2.9 0.3 9.1 0.0 0.4 0.0 0.8 0.1 0.1 0.2 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGS11 ENSG00000076344 "Regulator of G protein signaling 11" O94810 16 268301-275980 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.2;pituitary gland: 56.4" "Cell type enhanced" "Detected in many" "Astrocytes: 31.0;Bipolar cells: 69.7;Cone photoreceptor cells: 120.9;Excitatory neurons: 31.9;Inhibitory neurons: 33.6;Oligodendrocytes: 28.0;Rod photoreceptor cells: 67.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;ASC TERT1: 2.2;fHDF/TERT166: 2.0;HHSteC: 3.1;hTERT-RPE1: 2.4;SCLC-21H: 3.0;SH-SY5Y: 2.3;T-47d: 2.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041692, HPA043039" Uncertain NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA041692: AB_2677619, HPA043039: AB_2678282" "unprognostic (8.39e-2)" "unprognostic (1.97e-1)" "unprognostic (5.46e-2)" "unprognostic (4.55e-3)" "unprognostic (1.46e-1)" "unprognostic (8.50e-2)" "unprognostic (7.48e-2)" "unprognostic (2.02e-1)" "unprognostic (2.93e-1)" "unprognostic (6.56e-2)" "prognostic favorable (1.24e-4)" "unprognostic (1.70e-1)" "unprognostic (1.48e-3)" "unprognostic (6.91e-3)" "unprognostic (2.27e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" 14.7 4.5 13.4 1.0 14.8 0.0 8.4 21.8 40.2 8.8 7.5 21.7 7.1 4.2 0.3 7.4 4.5 0.9 22.3 13.4 11.2 5.4 2.4 9.0 0.4 15.4 14.2 0.8 16.8 4.4 56.4 2.6 15.3 19.2 0.7 8.9 3.8 2.7 2.2 2.5 6.9 1.1 10.2 3.4 15.0 0.8 12.8 0.0 4.2 1.1 0.0 9.2 8.8 14.4 0.0 0.0 0.0 0.0 2.1 2.2 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 1.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.8 0.0 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.0 0.2 0.0 0.0 3.0 2.3 1.2 0.0 0.5 0.0 2.5 0.0 1.6 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 14.8 21.8 40.2 13.4 11.2 15.4 14.2 15.3 10.2 12.8 14.4 1.8 0.0 0.0 31.0 0.1 0.1 0.2 0.1 0.6 69.7 1.0 0.6 7.5 1.5 0.0 0.0 120.9 0.1 0.3 0.9 0.0 0.1 0.0 1.9 5.2 1.8 10.3 0.0 31.9 1.0 0.2 8.6 3.1 3.3 0.0 0.4 6.1 0.0 0.2 10.1 33.6 0.4 2.0 0.0 1.1 0.0 0.9 0.2 1.8 4.7 0.6 3.3 0.0 18.1 28.0 0.4 7.1 1.9 0.0 0.5 5.8 0.0 0.0 67.5 0.0 1.5 7.2 0.5 1.5 0.3 0.6 0.8 0.3 0.1 1.4 0.1 RHOBTB1 KIAA0740 ENSG00000072422 "Rho related BTB domain containing 1" O94844 10 60869438-61001440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 144.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5;Horizontal cells: 334.8;Oligodendrocytes: 155.5;Syncytiotrophoblasts: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040205, HPA040226" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA040205: AB_2676883, HPA040226: AB_10795377" "unprognostic (1.25e-1)" "unprognostic (2.72e-2)" "unprognostic (6.69e-3)" "unprognostic (2.63e-2)" "unprognostic (1.08e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-3)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (4.31e-1)" "unprognostic (1.39e-1)" "unprognostic (5.53e-2)" "unprognostic (8.54e-3)" "unprognostic (1.38e-1)" "unprognostic (1.79e-1)" "unprognostic (7.16e-2)" "unprognostic (2.57e-2)" 7.8 13.9 5.6 4.1 6.6 0.9 7.1 5.2 7.8 15.7 5.3 8.1 6.6 14.5 2.4 3.0 10.9 11.5 13.5 4.6 4.7 30.8 6.8 10.6 2.8 6.1 6.1 10.2 9.2 8.6 3.2 37.1 6.3 7.7 4.8 24.3 2.1 9.9 144.2 3.6 5.6 12.1 4.9 14.9 20.8 15.1 7.6 1.9 3.3 19.6 1.2 7.4 7.5 7.8 0.2 12.0 17.8 0.0 8.3 7.3 0.0 5.3 4.8 4.3 6.4 0.6 0.2 0.0 21.9 28.0 2.0 0.3 5.3 1.6 5.0 0.0 4.8 1.1 8.8 67.3 9.0 1.4 0.4 10.6 3.0 2.6 2.7 16.5 20.6 3.8 10.2 0.0 19.1 0.4 5.2 0.0 7.7 0.2 7.9 4.5 24.9 6.4 14.1 0.7 4.9 19.0 6.3 6.9 6.9 11.1 1.4 2.4 18.5 8.2 21.1 0.2 5.9 0.0 0.0 0.0 4.1 3.9 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 5.6 6.6 5.2 7.8 4.6 4.7 6.1 6.1 6.3 4.9 7.6 7.8 13.7 16.0 8.7 3.6 1.0 1.8 1.0 0.5 0.6 3.4 3.7 2.5 29.5 1.5 2.3 1.8 135.5 66.1 0.2 0.7 1.9 3.8 75.2 11.0 14.7 13.6 8.3 3.8 74.3 16.0 3.4 8.6 34.1 4.5 0.0 59.0 17.9 9.6 11.3 334.8 23.1 7.7 4.1 21.5 1.4 35.3 8.1 14.1 1.8 57.1 0.4 16.0 0.0 14.1 155.5 16.4 2.5 4.9 0.1 1.2 1.5 36.4 10.2 25.1 6.6 16.7 11.8 2.8 1.4 0.6 1.4 302.4 0.8 15.2 4.3 0.4 RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 478.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 67.3;Gastric mucus-secreting cells: 47.4;Hepatocytes: 55.8;Intestinal goblet cells: 110.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 92.6;ASC TERT1: 107.2;Hep G2: 136.9;HSkMC: 63.1;OE19: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 61000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" 106.4 7.8 5.5 8.9 5.7 1.2 96.6 5.4 8.3 95.6 8.5 56.5 22.0 59.2 37.0 20.1 77.3 55.6 44.1 5.5 8.1 40.3 478.8 40.3 12.2 6.9 6.6 111.7 41.0 14.7 12.5 5.7 6.9 76.7 65.2 4.7 74.8 45.8 14.1 47.4 41.9 25.9 6.7 11.8 84.7 10.6 5.3 5.8 26.5 31.5 10.6 65.3 75.9 7.8 2.7 12.1 2.6 0.1 92.6 107.2 0.5 10.5 23.8 1.4 4.5 3.4 4.1 0.1 2.9 24.6 6.2 2.5 1.4 2.6 1.7 17.2 1.8 0.3 2.9 136.9 10.2 1.3 0.6 63.1 5.8 1.6 10.3 34.6 12.6 4.2 0.1 12.2 6.9 1.5 1.0 0.2 0.5 92.3 10.3 0.6 2.1 3.6 2.9 2.4 0.1 0.5 5.0 2.3 2.6 4.2 3.4 0.2 13.3 3.0 1.7 4.1 0.3 2.6 3.5 0.4 4.7 1.3 2.7 0.2 24.1 0.1 0.8 1.2 1.0 5.3 1.5 0.6 13.8 4.9 0.3 0.6 0.6 0.6 0.1 3.3 3.3 8.4 5.5 5.7 5.4 8.3 5.5 8.1 6.9 6.6 6.9 6.7 5.3 7.8 1.8 38.5 19.1 2.0 3.4 2.8 1.7 2.5 11.4 0.0 9.9 2.5 0.2 28.6 4.7 3.7 0.0 0.2 0.3 30.4 0.0 34.4 0.2 0.1 0.8 4.0 67.3 8.4 0.1 22.2 0.4 39.2 47.4 0.8 1.3 0.3 5.0 55.8 1.6 0.0 0.2 110.0 2.0 6.2 4.0 0.3 12.5 3.6 3.6 1.9 2.7 1.3 1.0 0.0 0.9 12.8 33.2 4.1 5.9 1.7 41.7 10.2 11.6 0.3 0.0 2.6 8.1 0.2 0.1 10.2 4.1 0.4 0.8 0.1 39.6 1.5 ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 309.4;Inhibitory neurons: 1518.9;Oligodendrocyte precursor cells: 348.3;Oligodendrocytes: 479.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" 12.4 8.6 12.7 10.7 13.7 0.2 4.9 4.3 9.5 13.4 0.0 7.8 3.1 9.5 7.2 12.3 4.7 7.7 6.7 7.8 10.8 3.1 3.6 7.6 9.3 8.8 16.3 16.4 1.9 1.8 7.4 7.8 9.9 12.9 6.0 3.9 5.4 11.9 4.5 20.5 4.3 10.5 7.5 9.0 4.8 10.3 15.5 13.3 4.8 5.4 18.2 13.9 11.1 12.4 0.2 26.9 25.7 41.3 35.0 22.8 1.4 21.1 28.0 16.3 13.8 0.6 11.5 0.0 0.1 26.2 13.0 10.9 31.5 21.6 20.5 0.4 39.1 16.4 51.4 43.4 8.4 0.3 4.1 38.3 28.9 61.9 29.1 30.5 16.5 0.0 2.2 49.0 16.8 13.1 0.0 0.1 32.8 7.9 9.6 0.9 27.2 0.3 0.1 8.9 19.7 13.7 45.5 9.9 16.2 24.6 31.8 0.4 0.3 54.1 23.4 32.7 36.1 1.7 0.0 0.0 49.2 0.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 12.7 13.7 4.3 9.5 7.8 10.8 8.8 16.3 9.9 7.5 15.5 12.4 4.3 3.2 11.0 81.0 1.9 33.1 20.6 17.9 39.9 11.7 4.1 3.6 3.6 0.0 9.0 7.3 4.2 9.7 0.0 0.1 0.0 0.5 23.9 1.6 23.2 14.3 1.2 4.0 309.4 0.2 8.3 34.6 3.6 2.3 1.3 5.1 16.1 0.3 1.5 1.7 1518.9 1.4 22.4 2.6 10.0 65.9 19.9 1.5 14.2 51.5 1.9 5.7 0.0 348.3 479.3 0.2 5.1 24.5 1.3 20.5 4.9 0.4 2.9 1.0 13.1 24.7 16.8 2.7 7.0 30.3 33.8 5.6 0.9 71.1 2.6 52.7 ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.4" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Muller glia cells: 45.3" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "AF22: 18.4" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" 2.8 1.8 0.5 0.0 0.3 0.2 1.9 0.0 3.2 0.7 0.0 1.3 0.3 0.8 0.0 0.7 2.0 0.0 1.8 0.7 0.2 1.6 0.4 1.1 0.1 0.9 0.9 6.4 0.7 0.0 0.8 0.2 0.2 1.4 0.0 0.2 1.2 0.0 0.5 0.7 0.9 0.8 0.2 1.6 0.6 1.2 1.7 0.0 1.4 0.0 0.0 0.7 1.2 0.9 0.0 0.0 18.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.6 0.9 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.0 3.2 0.7 0.2 0.9 0.9 0.2 0.2 1.7 0.9 13.2 0.0 7.3 32.3 0.4 2.9 14.5 16.2 4.0 1.9 5.9 10.9 2.7 1.5 5.9 12.9 0.0 0.2 8.5 2.1 0.0 9.3 0.4 0.4 0.5 11.4 3.5 2.1 6.9 0.8 0.2 19.0 0.5 0.7 8.9 19.0 7.5 0.3 1.6 0.0 2.3 2.4 10.2 1.6 20.1 0.6 13.4 8.0 3.6 11.2 1.6 45.3 8.2 4.5 9.2 1.2 2.5 8.2 0.7 8.2 1.0 0.8 0.6 2.1 0.0 14.3 4.4 10.1 10.8 2.3 1.0 0.1 3.6 3.5 2.7 6.5 ROGDI FLJ22386 ENSG00000067836 "Rogdi atypical leucine zipper" Q9GZN7 16 4796968-4802880 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amelogenesis imperfecta, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 179.2;Rod photoreceptor cells: 149.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 74.6;intermediate monocyte: 62.7;myeloid DC: 61.5;non-classical monocyte: 61.8;plasmacytoid DC: 34.5" "Group enriched" "Detected in all" 6 "dendritic cells: 61.5;monocytes: 74.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041000 Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" "HPA041000: AB_10794077" "unprognostic (1.74e-3)" "unprognostic (1.98e-3)" "unprognostic (1.25e-1)" "unprognostic (1.01e-2)" "unprognostic (1.68e-1)" "unprognostic (1.95e-1)" "unprognostic (3.13e-1)" "unprognostic (3.79e-3)" "unprognostic (3.22e-2)" "unprognostic (1.21e-1)" "prognostic favorable (9.71e-4)" "unprognostic (5.24e-2)" "prognostic favorable (2.67e-5)" "unprognostic (1.71e-1)" "unprognostic (7.16e-2)" "unprognostic (2.17e-1)" "unprognostic (3.08e-2)" 7.5 24.1 82.9 11.6 84.5 78.0 7.3 81.3 105.6 8.8 64.3 17.6 24.8 7.5 6.6 18.1 14.5 14.4 44.2 91.4 83.9 19.3 19.7 15.5 8.6 84.0 84.9 5.9 22.9 26.4 18.2 7.9 80.9 19.0 7.6 61.9 25.3 16.6 63.1 6.5 21.4 11.3 79.4 15.6 21.1 8.2 96.8 10.1 4.6 32.9 8.7 11.2 6.4 97.6 13.5 18.8 9.5 42.4 12.2 6.2 36.4 9.4 4.6 8.2 3.6 12.5 15.3 5.9 15.1 19.9 5.3 26.7 9.9 28.7 3.2 4.8 13.3 8.0 28.9 28.1 19.8 10.4 6.5 8.3 11.7 12.4 8.3 21.6 14.5 11.5 5.7 3.5 14.1 74.9 9.4 51.0 15.3 15.4 14.2 30.1 26.1 30.1 19.8 18.1 55.3 24.5 38.6 42.4 9.9 11.9 50.9 40.8 22.3 7.3 17.0 52.5 6.5 14.2 17.0 5.2 8.6 40.0 6.5 10.5 74.6 8.1 2.1 62.7 6.6 2.5 5.4 4.9 61.5 2.8 4.7 5.5 6.7 6.7 61.8 34.5 6.1 38.0 82.9 84.5 81.3 105.6 91.4 83.9 84.0 84.9 80.9 79.4 96.8 97.6 7.0 19.2 7.8 17.3 6.7 5.1 28.0 84.4 32.5 179.2 23.0 22.5 58.1 21.5 36.7 27.6 110.5 46.9 11.5 23.4 39.2 22.2 30.3 17.6 8.5 12.0 52.0 38.7 33.2 16.0 73.4 15.9 11.7 7.2 5.7 9.8 24.3 19.7 64.8 25.2 19.2 29.7 69.2 28.7 29.0 57.0 6.8 31.0 12.4 10.3 77.0 102.5 6.2 7.5 90.2 13.5 23.7 19.2 4.6 12.7 65.7 80.8 21.3 149.7 6.6 8.2 15.3 6.5 20.7 24.8 5.8 30.6 9.5 64.7 23.1 22.3 ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Astrocytes: 81.0;Inhibitory neurons: 69.7;Microglial cells: 36.5;Oligodendrocytes: 109.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 40.5;ASC TERT1: 50.3;CACO-2: 36.8;HHSteC: 38.3;HSkMC: 41.6;NTERA-2: 43.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" NA NA 7700000 "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" 4.4 1.1 0.6 2.2 1.4 0.4 3.7 3.0 0.8 7.5 4.6 4.5 2.2 7.1 1.4 5.2 2.5 5.2 7.5 0.7 0.6 2.3 0.5 7.0 1.2 0.7 0.9 8.3 5.5 26.9 0.5 3.1 0.5 5.4 4.0 1.5 1.2 6.4 2.3 2.3 1.7 7.7 0.3 3.2 6.4 1.5 1.2 2.5 1.4 1.6 1.1 4.2 2.3 1.1 15.5 12.2 5.9 0.8 40.5 50.3 4.0 2.9 8.3 1.6 4.3 36.8 4.9 0.3 6.6 7.2 2.9 3.2 0.1 2.9 1.1 0.0 3.7 0.0 1.6 0.5 38.3 0.0 0.0 41.6 10.9 21.7 25.2 8.4 0.7 0.5 0.0 0.3 11.0 0.2 0.2 0.1 43.0 11.3 6.1 0.2 0.2 9.8 8.7 0.3 3.4 13.6 0.8 0.2 6.4 19.9 0.1 0.0 8.4 3.3 5.7 23.0 6.2 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.6 1.4 3.0 0.8 0.7 0.6 0.7 0.9 0.5 0.3 1.2 1.1 1.1 51.3 10.5 81.0 1.8 3.8 2.2 0.5 29.0 4.7 3.0 2.0 11.4 1.5 1.3 1.8 0.0 0.2 0.1 1.3 0.0 5.6 9.6 1.2 9.2 1.8 21.5 0.0 11.6 15.2 1.0 14.5 16.8 1.9 0.0 1.1 0.7 0.0 7.6 0.0 69.7 2.2 2.0 0.6 4.9 8.1 27.7 0.5 3.6 36.5 0.0 5.3 0.0 3.5 109.9 15.3 0.8 14.7 0.1 1.4 0.0 3.4 0.8 0.3 6.6 6.8 8.5 1.4 1.8 11.5 4.5 0.3 0.2 0.3 3.3 0.8 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 RUSC1 NESCA ENSG00000160753 "RUN and SH3 domain containing 1" Q9BVN2 1 155320894-155331114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028510, HPA029922, HPA029923" Approved Enhanced Cytosol NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA028510: AB_10599847, HPA029922: AB_10611390, HPA029923: AB_10602288" "unprognostic (1.98e-1)" "unprognostic (2.82e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-1)" "unprognostic (5.25e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.78e-6)" "unprognostic (1.42e-1)" "unprognostic (1.38e-1)" "unprognostic (1.73e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (9.24e-6)" "unprognostic (7.59e-2)" "unprognostic (4.25e-2)" "unprognostic (2.05e-2)" "unprognostic (1.40e-1)" 27.0 26.6 42.0 11.6 40.7 12.8 23.2 39.9 66.0 38.0 11.3 39.2 21.6 28.8 8.7 49.5 24.8 16.8 28.8 38.9 41.1 32.1 12.6 23.7 10.7 55.2 34.0 27.5 22.5 11.7 45.0 18.2 53.2 32.1 22.9 11.9 32.0 20.3 14.1 37.3 29.9 18.6 28.3 18.0 27.3 6.6 41.4 18.6 19.3 13.3 11.3 26.6 39.2 41.0 70.4 43.5 24.5 36.4 29.6 32.1 47.2 32.7 20.8 42.2 47.1 50.1 45.2 13.7 24.4 33.2 24.2 95.1 38.3 47.4 18.2 18.8 48.8 19.8 44.7 26.6 24.5 19.9 32.9 33.0 29.3 42.5 14.6 20.4 43.9 29.7 30.5 9.4 36.9 133.4 25.0 25.3 48.4 128.4 68.3 33.6 17.1 24.3 40.3 52.7 25.2 40.5 27.6 76.9 16.8 39.8 114.8 33.6 20.2 54.0 44.4 51.4 65.8 7.4 18.0 8.6 38.2 26.5 15.0 5.8 8.0 4.0 6.3 9.8 7.2 3.6 5.1 6.4 8.8 1.5 2.8 6.0 1.1 3.3 25.2 8.4 5.5 5.4 42.0 40.7 39.9 66.0 38.9 41.1 55.2 34.0 53.2 28.3 41.4 41.0 18.2 9.6 12.7 4.9 8.0 28.0 20.1 29.5 22.8 16.9 21.3 19.3 10.2 15.7 27.9 18.4 6.2 30.8 14.8 82.2 23.5 22.4 0.4 9.9 14.7 20.0 15.6 14.5 23.8 17.7 76.6 19.1 25.5 23.6 8.2 9.8 16.4 7.8 21.0 37.0 30.5 51.7 18.3 12.8 20.3 0.5 18.3 11.9 19.6 6.5 11.7 13.4 15.5 7.1 8.2 25.6 43.7 18.0 8.4 29.4 51.8 27.9 10.4 7.0 19.7 12.7 22.2 2.3 8.9 41.4 34.9 38.0 15.2 6.7 40.1 26.0 RXRG NR2B3 ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.1;pituitary gland: 29.9;retina: 24.3;skeletal muscle: 49.7" "Group enriched" "Detected in some" 4 "Astrocytes: 13.4;Cone photoreceptor cells: 25.0;Melanocytes: 28.4;Muller glia cells: 16.8;Sertoli cells: 13.1;Skeletal myocytes: 35.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SK-MEL-30: 39.4" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" 2.4 3.2 14.6 0.4 16.6 0.0 1.0 11.7 17.4 3.0 11.7 4.1 0.7 1.1 0.7 1.0 2.8 0.6 5.3 12.4 21.5 0.2 0.3 2.8 0.3 25.6 14.8 1.0 2.1 0.1 29.9 0.7 22.2 1.1 2.0 24.3 1.2 1.4 49.7 2.3 1.6 1.2 13.6 0.4 1.4 1.0 32.1 0.1 0.7 7.6 0.0 1.6 2.1 15.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 16.6 11.7 17.4 12.4 21.5 25.6 14.8 22.2 13.6 32.1 15.6 0.9 0.0 0.0 13.4 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.3 0.0 0.0 4.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.3 2.8 5.0 0.0 28.4 0.0 0.0 16.8 0.0 1.0 1.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 4.5 13.1 35.9 3.4 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1760.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3820.4;Langerhans cells: 3945.6;Pancreatic endocrine cells: 4570.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2005.4;monocytes: 1235.2;T-cells: 1180.0" "Cell line enhanced" "Detected in all" "OE19: 4936.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" 775.1 376.9 71.1 244.8 76.6 133.7 519.6 75.5 139.8 478.0 78.5 867.3 461.4 110.1 56.7 1760.5 188.7 212.4 340.9 72.4 132.8 735.0 157.7 689.8 133.3 148.2 105.0 234.0 145.0 36.3 71.0 326.9 108.5 164.9 924.2 51.3 422.8 105.0 106.0 483.4 448.0 288.2 98.2 111.2 189.1 145.8 138.8 118.3 143.5 145.4 289.8 338.4 803.1 110.3 1251.3 1085.9 3.4 241.6 1351.4 1711.3 972.5 730.1 912.1 613.8 606.5 1975.4 1671.4 2.3 689.1 1208.0 661.7 2227.5 337.0 2786.6 495.3 242.5 127.1 163.8 461.5 468.1 507.0 60.2 126.7 470.8 2195.5 660.6 738.6 487.6 1326.0 78.9 2.9 3.6 753.8 940.0 11.0 376.5 163.6 4936.7 1671.4 1.6 242.4 27.1 2348.3 317.0 11.1 9.5 1259.2 374.3 539.8 1213.0 882.2 130.5 1654.9 285.5 737.2 1362.3 459.2 34.4 7.8 225.2 1709.5 51.7 977.8 359.5 1235.2 299.7 425.7 758.7 443.3 232.4 652.3 539.0 2005.4 140.1 237.7 363.1 43.6 355.0 664.7 329.6 1180.0 1313.4 71.1 76.6 75.5 139.8 72.4 132.8 148.2 105.0 108.5 98.2 138.8 110.3 1197.3 2554.5 537.7 3.9 244.0 1594.8 1171.4 2183.2 795.6 11.6 241.1 281.4 111.2 693.4 994.6 950.9 4.2 1271.5 476.2 3820.4 1524.1 1811.7 314.2 901.0 104.6 1061.2 1078.1 114.2 0.4 2105.0 527.4 1751.3 432.8 1270.7 289.5 840.0 864.5 206.9 1023.1 16.8 0.9 1723.1 272.6 795.2 3945.6 274.2 647.1 1338.1 1632.8 28.1 1544.2 24.8 285.3 4.0 0.6 4570.5 3391.8 64.7 244.5 2782.5 2146.1 495.6 620.3 32.5 144.7 801.6 529.5 30.4 115.9 1940.1 1242.0 375.8 801.0 38.5 1998.0 2290.6 S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 2708.8;Langerhans cells: 5952.7;Macrophages: 2786.0;monocytes: 3172.6;NK-cells: 2130.8;Skeletal myocytes: 2034.0;T-cells: 2111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 2614.3;ASC diff: 3300.1;BJ hTERT+: 6738.6;fHDF/TERT166: 4819.1;RPMI-8226: 2700.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 39.6" "CAB002618, HPA007486, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 9600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007486: , HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" 982.3 77.1 25.5 353.9 26.2 1090.8 561.9 27.5 53.1 566.3 32.0 301.7 91.7 177.8 124.5 224.0 217.6 167.6 268.5 24.7 27.4 247.0 64.3 874.2 221.0 31.7 26.4 51.0 53.8 18.1 24.8 182.9 29.8 223.7 331.5 10.0 245.4 155.8 163.0 371.5 234.3 297.7 27.8 443.0 133.3 32.2 33.7 112.6 191.9 424.6 315.4 391.6 455.2 34.1 11.8 2614.3 13.2 77.0 3300.1 2410.9 3.7 1664.4 6738.6 32.1 148.4 20.0 180.3 0.8 299.7 4819.1 3.5 65.3 8.8 20.9 23.6 405.2 2.3 1186.8 529.0 59.4 4.3 106.9 1924.6 364.2 21.5 62.2 13.0 4.9 2.6 0.7 9.9 4.2 2468.1 10.6 3.8 1273.9 7.2 189.7 1050.4 64.1 3.7 2700.2 103.5 71.3 108.5 11.6 24.9 1286.6 9.4 412.5 77.1 1493.7 3.1 8.5 13.7 2159.5 9.3 82.8 647.5 14.3 6.1 1367.9 127.2 2789.7 13536.2 1408.0 5800.5 9099.6 6077.0 761.6 5167.7 4700.0 9268.4 282.5 882.4 2641.3 12129.7 837.1 11862.4 1626.0 7406.7 24075.8 25.5 26.2 27.5 53.1 24.7 27.4 31.7 26.4 29.8 27.8 33.7 34.1 226.0 490.4 398.4 0.0 266.1 772.9 19.5 159.0 93.9 0.7 44.9 65.9 14.9 35.8 273.8 893.8 0.0 52.4 1345.4 8.9 111.6 21.9 7.3 53.0 473.0 209.1 4.8 730.9 0.0 23.5 255.5 1378.8 54.0 41.9 1395.8 0.6 96.4 18.6 1966.1 45.4 0.0 10.0 345.8 2708.8 5952.7 24.0 235.8 2786.0 1193.5 12.2 3172.6 3.6 2130.8 0.0 0.1 35.7 17.0 45.9 266.5 12.9 3.2 19.7 154.9 2.3 151.2 2034.0 1309.6 1.9 5.5 77.6 694.0 53.4 2111.1 32.5 11.3 73.1 SCN2B ENSG00000149575 "Sodium voltage-gated channel beta subunit 2" O60939 11 118162806-118176639 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;heart muscle: 12.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.8;Cardiomyocytes: 16.8;Excitatory neurons: 21.9;Horizontal cells: 13.5;Inhibitory neurons: 32.0;Oligodendrocytes: 7.4" "Cancer enhanced" "Detected in some" "glioma: 1.3;thyroid cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (9.01e-2)" "unprognostic (3.50e-2)" "unprognostic (7.58e-2)" "unprognostic (2.12e-2)" "unprognostic (1.41e-2)" "unprognostic (4.02e-1)" "unprognostic (2.71e-4)" "unprognostic (5.17e-2)" "unprognostic (8.59e-2)" "unprognostic (2.77e-1)" "unprognostic (7.89e-2)" "unprognostic (1.61e-2)" "unprognostic (3.51e-2)" "unprognostic (1.27e-2)" "unprognostic (4.35e-2)" "unprognostic (4.55e-1)" "unprognostic (2.88e-3)" 0.6 1.5 19.1 0.3 20.7 0.0 0.7 14.9 34.0 1.4 0.0 1.7 0.6 1.6 1.3 1.8 1.3 1.3 12.8 20.9 12.3 0.4 0.0 1.1 0.0 5.7 13.3 1.3 0.1 0.0 0.8 0.0 9.1 1.0 0.7 3.7 0.5 1.2 7.3 0.2 1.1 1.9 4.9 0.1 0.3 0.2 19.5 1.8 0.7 7.5 0.0 0.3 0.4 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 19.1 20.7 14.9 34.0 20.9 12.3 5.7 13.3 9.1 4.9 19.5 22.1 0.1 0.0 0.0 3.9 0.0 0.4 0.6 0.7 1.8 8.8 0.1 2.0 16.8 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.5 0.2 0.0 0.0 21.9 0.0 0.0 1.6 0.0 0.3 0.0 0.2 0.0 0.0 0.1 13.5 32.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.9 0.0 0.9 0.0 2.5 7.4 0.0 0.0 2.2 0.0 0.2 0.0 0.0 0.1 1.9 0.0 0.9 0.8 0.1 0.6 0.0 0.1 0.0 0.1 0.5 0.0 0.3 SCN4B LQT10 ENSG00000177098 "Sodium voltage-gated channel beta subunit 4" Q8IWT1 11 118133377-118152888 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 109.6;tongue: 56.8" "Cell type enhanced" "Detected in many" "Adipocytes: 12.3;Excitatory neurons: 18.2;Sertoli cells: 46.0;Smooth muscle cells: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.3;HBEC3-KT: 1.0;NTERA-2: 1.4;U-2 OS: 1.2" "Region enriched" "Detected in all" 11 "basal ganglia: 816.3" "Region enriched" "Detected in many" 4 "basal ganglia: 134.6" HPA017293 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "HPA017293: AB_2184174" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-1)" "unprognostic (1.07e-1)" "unprognostic (9.82e-3)" "unprognostic (9.17e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-2)" "unprognostic (1.07e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-3)" "unprognostic (1.53e-1)" "unprognostic (5.31e-4)" 23.5 5.4 2.6 1.2 86.6 0.0 9.2 41.3 109.6 2.1 0.0 2.6 2.4 3.1 1.6 5.3 5.4 3.2 11.8 2.1 14.0 2.1 0.4 8.9 2.1 53.3 15.4 0.5 5.1 6.8 2.7 1.8 45.9 2.2 2.1 0.9 2.5 2.3 30.4 3.9 4.7 7.1 15.2 0.0 2.9 0.7 23.1 8.6 14.5 56.8 0.7 3.0 1.4 28.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 86.6 41.3 109.6 2.1 14.0 53.3 15.4 45.9 15.2 23.1 28.5 12.3 0.0 0.0 2.9 0.0 1.3 0.6 2.0 2.8 1.7 0.5 5.7 4.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 3.0 0.0 0.0 18.2 0.0 0.1 3.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 8.2 0.0 2.0 1.2 1.4 8.7 2.1 1.1 0.0 1.9 0.0 0.5 0.0 1.5 1.4 0.0 0.0 1.5 0.0 0.1 0.0 0.1 5.8 0.8 46.0 0.6 38.8 0.1 0.6 0.5 1.1 0.0 0.1 0.0 0.0 0.2 SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2087.6;liver: 6268.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 448.7;Alveolar cells type 2: 529.3;Granulosa cells: 458.1;Hofbauer cells: 858.5;Macrophages: 373.3;Proximal tubular cells: 1044.7" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Hep G2: 567.4;HSkMC: 451.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA 2220000000 1800000000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" 719.1 424.3 164.8 179.9 345.6 40.1 617.5 386.0 290.0 460.0 145.5 644.0 620.0 335.8 459.7 240.7 376.5 670.5 237.2 156.3 231.3 853.7 6268.1 512.0 552.4 519.4 316.4 701.2 229.0 246.0 108.3 973.0 490.3 214.2 714.2 59.2 170.8 374.1 156.4 171.8 2087.6 233.2 310.3 948.8 257.0 87.8 284.7 170.4 147.0 265.6 177.4 414.3 213.1 524.3 0.7 1.7 7.7 1.0 43.6 12.2 7.3 4.1 10.9 0.0 0.0 12.5 65.3 2.0 36.3 1.5 1.4 1.7 0.2 0.1 0.0 2.4 52.7 3.1 0.2 567.4 25.9 3.2 0.4 451.1 0.7 0.0 0.1 1.9 0.1 1.5 6.4 12.9 23.5 1.3 1.1 6.4 30.6 17.0 0.9 1.3 2.0 100.8 12.5 8.0 2.2 2.7 2.7 16.7 1.6 54.6 125.4 0.7 0.7 3.2 1.7 5.2 1.0 8.4 1.5 2.0 1.7 5.9 1.5 0.1 0.1 0.5 0.5 0.1 0.6 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.5 0.6 0.2 0.9 0.3 0.3 164.8 345.6 386.0 290.0 156.3 231.3 519.4 316.4 490.3 310.3 284.7 524.3 312.7 448.7 529.3 0.0 15.2 0.0 0.0 0.0 0.0 0.0 312.0 271.1 0.0 0.0 102.1 125.0 0.0 223.4 9.4 0.0 197.6 73.4 0.0 83.8 231.0 75.8 0.0 0.0 0.0 52.8 17.5 358.7 0.0 116.1 26.5 458.1 0.0 0.0 858.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 373.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 33.2 0.0 0.0 4.9 0.0 0.0 1044.7 52.5 0.0 0.0 0.0 133.1 0.0 0.0 0.0 0.0 112.9 10.0 361.8 0.0 0.0 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SEMA5A "SEMAF, semF" ENSG00000112902 "Semaphorin 5A" Q13591 5 9035033-9546075 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 1189.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.2;fHDF/TERT166: 37.1;RT4: 66.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004632 Approved NA NA 13000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" "HPA004632: AB_1079905" "unprognostic (1.48e-1)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "unprognostic (6.67e-2)" "unprognostic (3.65e-1)" "prognostic favorable (2.45e-4)" "unprognostic (7.02e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (8.15e-2)" "prognostic favorable (3.66e-8)" "unprognostic (8.51e-3)" "unprognostic (1.27e-2)" "unprognostic (3.57e-1)" "unprognostic (3.01e-2)" 4.6 1.2 7.8 2.7 9.1 0.0 6.8 5.6 23.6 13.0 3.6 9.5 2.9 8.9 2.2 3.1 2.9 5.4 9.5 35.4 17.0 11.6 4.9 11.1 4.7 10.9 11.1 1.7 4.4 1.9 2.3 7.0 17.1 2.9 7.5 7.0 2.1 4.9 1.3 4.4 5.3 2.4 8.3 6.3 1.9 1.6 16.4 1.7 1.9 3.1 3.7 5.8 3.8 13.4 0.0 0.0 15.0 0.0 10.1 14.1 0.0 24.2 64.2 4.7 2.5 0.0 0.1 0.0 0.0 37.1 0.3 21.6 0.0 1.4 2.4 0.0 0.2 0.0 0.1 0.0 1.4 0.0 0.1 3.6 0.7 5.3 21.6 10.5 0.0 0.0 0.0 0.0 5.7 0.7 0.0 0.0 1.5 13.2 1.1 0.0 0.0 0.9 1.8 66.7 3.1 0.3 0.2 0.0 19.9 5.1 0.0 0.0 0.0 23.0 0.5 0.0 0.5 0.0 0.0 0.0 21.4 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 7.8 9.1 5.6 23.6 35.4 17.0 10.9 11.1 17.1 8.3 16.4 13.4 8.0 150.6 5.6 63.6 0.3 9.2 6.4 30.8 8.0 2.8 1.6 49.0 37.0 22.8 14.3 1.8 0.0 1.8 9.6 23.9 0.0 3.4 32.6 6.3 151.5 6.4 5.4 0.0 60.6 2.3 1.2 27.8 0.5 9.3 1.3 1.8 5.3 4.3 1.3 247.3 53.1 10.9 0.0 0.0 5.2 50.5 10.2 0.8 33.8 134.9 0.1 44.8 0.0 1189.7 152.3 1.2 8.0 14.7 0.0 8.2 16.9 14.4 2.0 3.6 39.5 4.3 40.5 0.6 0.5 11.4 4.8 1.9 1.4 29.0 20.5 14.1 SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Excitatory neurons: 30.8;Muller glia cells: 7.3;Oligodendrocyte precursor cells: 45.2;Smooth muscle cells: 14.3" "Cancer enhanced" "Detected in many" "renal cancer: 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 79.7;NTERA-2: 15.7;SH-SY5Y: 21.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA066548: AB_2685689" "unprognostic (7.34e-2)" "unprognostic (1.84e-3)" "unprognostic (1.92e-4)" "unprognostic (3.01e-2)" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "unprognostic (4.72e-2)" "unprognostic (1.58e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (1.31e-3)" "unprognostic (5.96e-2)" "unprognostic (6.12e-2)" "unprognostic (2.12e-1)" 1.7 1.5 12.1 0.4 11.8 0.0 1.3 7.3 15.9 1.8 6.7 1.3 0.9 1.4 2.8 0.7 3.5 2.5 9.5 16.2 8.0 9.1 0.9 1.2 0.6 8.4 8.5 1.4 1.7 0.6 2.7 2.6 9.7 1.4 0.8 7.1 0.4 1.4 0.9 1.5 1.5 1.9 7.7 0.2 0.6 0.7 7.8 0.2 2.6 0.5 0.6 1.6 1.6 10.9 0.0 0.0 79.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 21.3 0.0 0.2 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 11.8 7.3 15.9 16.2 8.0 8.4 8.5 9.7 7.7 7.8 10.9 1.2 0.0 1.1 9.4 0.0 0.0 0.0 0.1 0.0 7.2 0.1 0.0 3.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.8 0.0 0.0 30.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.6 7.3 0.0 45.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 14.3 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907105 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 570.9" "Group enriched" "Detected in some" 4 "Adipocytes: 192.1;Cardiomyocytes: 227.0;Cytotrophoblasts: 171.4;dendritic cells: 196.6;Extravillous trophoblasts: 198.2;Fibroblasts: 153.5;Hofbauer cells: 191.0;Smooth muscle cells: 190.0;Syncytiotrophoblasts: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Approved "Nucleoli,Plasma membrane,Actin filaments,Midbody,Cytosol" Yes No 4300000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoli, Plasma membrane, Midbody, Cytosol" "HPA023309: AB_10600093, HPA029524: AB_10601573" "unprognostic (7.91e-3)" "unprognostic (6.89e-3)" "unprognostic (9.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (2.00e-2)" "unprognostic (4.43e-2)" "unprognostic (7.13e-2)" "unprognostic (3.56e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (2.43e-3)" 127.1 95.1 352.6 98.8 386.1 131.0 99.5 334.3 570.9 111.5 289.5 116.4 55.7 126.5 121.5 106.6 84.1 117.5 172.1 344.1 341.6 82.9 76.9 98.6 150.9 337.4 355.9 138.2 37.0 81.1 62.6 143.5 339.1 93.9 94.8 119.5 50.3 95.5 82.9 105.0 74.9 145.2 345.1 108.3 59.4 70.3 367.7 159.0 78.2 104.3 149.7 125.0 86.9 411.9 198.1 94.3 232.0 153.2 256.7 263.1 119.3 248.6 228.6 206.7 177.0 147.7 148.9 186.2 164.2 254.9 274.9 146.3 166.3 166.4 294.0 127.8 88.4 149.8 123.4 80.8 149.4 182.7 157.7 171.7 127.1 163.8 159.4 215.6 221.0 143.3 120.1 141.9 341.6 92.8 185.6 304.3 249.7 183.1 132.6 188.3 220.9 107.6 202.6 146.1 124.3 217.4 173.5 220.1 151.8 377.1 163.1 198.7 187.3 207.2 246.7 129.9 278.5 165.9 163.4 470.2 132.4 301.2 449.3 266.8 86.0 150.1 214.8 100.1 220.7 165.6 151.5 199.6 100.8 155.5 134.4 171.2 160.9 298.7 110.5 71.0 147.4 241.7 352.6 386.1 334.3 570.9 344.1 341.6 337.4 355.9 339.1 345.1 367.7 411.9 192.1 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 227.0 0.0 0.0 0.0 0.0 171.4 196.6 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 198.2 153.5 0.0 0.0 0.0 0.0 0.0 0.0 191.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.0 0.0 0.0 0.0 0.0 124.2 30.4 0.0 0.0 0.0 SERP2 "bA269C23.1, C13orf21" ENSG00000151778 "Stress associated endoplasmic reticulum protein family member 2" Q8N6R1 13 44373665-44397714 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 87.7;choroid plexus: 53.7" "Group enriched" "Detected in many" 11 "Early spermatids: 577.8;Late spermatids: 237.7" "Cancer enhanced" "Detected in many" "glioma: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Lineage enhanced" "Detected in single" "granulocytes: 2.6" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.7;SH-SY5Y: 5.1;U-2197: 4.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038970 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA038970: AB_2676296" "unprognostic (6.55e-2)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (2.06e-1)" "unprognostic (9.62e-2)" "unprognostic (1.72e-2)" "unprognostic (2.85e-1)" "unprognostic (3.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (1.34e-3)" "unprognostic (1.12e-2)" "prognostic favorable (1.94e-4)" "unprognostic (1.48e-1)" "unprognostic (6.60e-2)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" 1.2 2.0 67.6 1.0 70.7 0.0 2.6 60.7 87.7 2.7 53.7 3.9 2.9 4.0 9.0 0.8 2.3 0.9 18.8 71.5 67.0 3.3 1.2 1.1 1.4 63.4 66.0 4.7 1.7 1.3 8.5 0.3 65.0 3.5 1.1 14.2 1.1 3.8 2.1 0.6 2.0 2.0 61.1 0.4 2.7 27.3 66.7 1.9 1.2 0.4 1.2 2.0 2.0 68.4 0.0 0.0 2.1 0.0 0.3 1.8 0.0 0.4 0.6 2.3 1.5 0.0 0.0 0.0 1.8 1.7 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.4 0.0 0.1 1.9 0.0 0.0 0.3 0.0 1.6 0.0 0.4 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.4 5.1 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.1 4.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 67.6 70.7 60.7 87.7 71.5 67.0 63.4 66.0 65.0 61.1 66.7 68.4 4.0 0.0 1.5 19.6 0.1 1.8 3.7 1.9 4.6 21.0 12.0 7.2 20.0 4.3 1.0 9.2 14.6 2.5 1.1 2.9 17.6 11.3 577.8 0.7 4.6 3.9 14.4 0.8 34.6 12.9 2.5 10.3 0.5 1.2 17.8 7.8 1.4 6.2 0.2 15.2 29.8 4.0 0.0 0.0 1.1 237.7 13.1 0.7 12.4 9.4 0.6 25.0 1.0 13.0 27.1 6.3 1.7 19.2 0.1 3.4 3.9 8.9 1.3 23.3 26.3 15.1 10.0 8.5 12.5 0.4 1.0 2.1 1.8 4.6 4.4 3.2 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 219.4;Excitatory neurons: 176.9;Inhibitory neurons: 228.8;Oligodendrocytes: 174.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 29.2;Karpas-707: 29.1;U-266/84: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" NA NA 750000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" 13.1 15.8 138.8 4.1 157.7 2.3 11.7 115.9 301.4 8.4 82.1 5.1 2.2 8.6 8.2 5.5 7.9 6.3 14.0 162.0 129.1 32.1 4.1 6.4 4.6 122.8 153.6 6.9 39.5 6.9 42.8 6.7 123.9 11.8 4.4 84.4 23.0 7.4 3.2 3.1 4.4 6.1 134.6 8.7 10.8 15.8 134.5 4.4 11.2 8.1 8.2 4.9 6.0 164.8 0.8 3.5 5.5 0.4 10.3 2.2 0.3 1.9 2.7 1.3 2.2 1.5 5.9 29.2 9.5 1.3 4.5 1.3 3.9 3.8 1.5 7.7 6.5 8.9 22.5 10.7 0.7 1.4 1.1 3.8 1.4 0.8 1.3 2.9 0.4 10.5 18.9 29.1 1.2 2.7 0.8 1.9 3.3 4.2 4.5 2.7 0.4 3.2 11.2 1.0 2.2 13.4 3.6 6.8 8.3 12.4 10.6 4.4 1.0 5.5 0.5 0.5 10.3 23.0 28.4 18.8 4.2 7.7 3.2 1.5 0.3 0.8 9.3 0.7 6.9 22.1 9.7 10.2 0.5 25.2 6.9 8.1 0.9 9.5 0.5 7.2 27.2 5.2 138.8 157.7 115.9 301.4 162.0 129.1 122.8 153.6 123.9 134.6 134.5 164.8 49.8 6.4 1.5 43.1 10.7 3.7 13.2 6.4 14.2 219.4 3.6 14.1 8.2 1.5 6.7 5.5 14.6 6.1 6.2 0.7 7.9 1.8 0.4 2.0 1.0 16.0 4.8 7.4 176.9 18.0 6.0 8.9 2.6 1.7 2.5 2.3 3.9 0.6 2.3 5.0 228.8 0.3 73.2 0.6 3.2 2.4 4.1 0.9 7.2 25.3 1.2 78.0 2.1 31.2 174.7 3.0 0.0 2.6 14.6 6.7 0.0 39.9 13.6 35.4 26.3 5.2 54.7 3.0 27.4 0.5 1.7 5.1 6.2 1.1 0.3 2.3 SERTAD4 DJ667H12.2 ENSG00000082497 "SERTA domain containing 4" Q9NUC0 1 210232796-210246631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 28.5;Breast glandular cells: 23.1;Extravillous trophoblasts: 54.9;Ionocytes: 24.4;Squamous epithelial cells: 27.4" "Cancer enhanced" "Detected in many" "breast cancer: 10.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 7.5;BEWO: 7.4;SCLC-21H: 7.4;SK-BR-3: 8.5;T-47d: 10.5;U-2 OS: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027344, HPA028514" Uncertain Supported Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA027344: AB_10601770, HPA028514: AB_10611391" "unprognostic (1.75e-2)" "unprognostic (3.92e-2)" "unprognostic (3.83e-2)" "unprognostic (9.74e-2)" "unprognostic (1.98e-2)" "unprognostic (1.27e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-1)" "unprognostic (7.74e-2)" "unprognostic (8.49e-2)" "unprognostic (1.69e-2)" "unprognostic (5.98e-2)" "unprognostic (6.24e-2)" "unprognostic (2.05e-1)" "unprognostic (3.85e-2)" "unprognostic (6.55e-2)" "unprognostic (4.24e-1)" 1.1 0.3 0.6 0.3 1.6 0.0 3.6 1.0 1.1 2.0 0.2 4.8 0.4 3.8 0.6 4.2 1.7 0.7 3.0 0.6 1.0 1.9 0.0 1.5 0.1 0.9 1.4 1.0 0.1 0.6 0.9 1.0 1.0 1.8 1.4 0.1 5.9 1.4 0.2 3.3 0.8 2.7 1.2 0.1 1.4 0.2 0.8 0.6 1.4 0.7 0.7 0.6 1.8 1.1 7.5 0.1 1.6 0.0 0.8 0.7 7.4 1.8 1.8 1.4 2.4 0.3 0.8 0.0 0.2 0.4 1.1 3.6 0.2 0.6 0.7 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 1.7 0.2 0.0 0.0 0.0 0.3 1.8 0.0 0.0 5.2 6.0 0.3 0.0 2.4 0.0 1.2 1.3 7.4 6.3 1.2 8.5 0.1 2.9 10.5 0.0 2.3 2.0 8.7 0.1 5.6 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.6 1.0 1.1 0.6 1.0 0.9 1.4 1.0 1.2 0.8 1.1 5.0 6.4 3.9 1.6 0.0 16.7 9.6 16.0 28.5 2.5 23.1 9.3 0.7 1.5 10.9 9.2 0.0 14.2 0.0 1.5 7.9 2.1 0.5 4.8 1.2 5.2 1.2 0.0 10.1 3.9 54.9 7.5 2.6 5.8 0.0 9.3 2.5 0.0 1.4 0.0 3.7 5.6 24.4 0.0 5.0 0.6 0.6 0.3 10.6 3.7 0.0 0.5 0.0 1.0 9.4 8.1 1.3 1.5 0.0 2.5 0.0 0.4 13.9 0.3 0.0 1.8 3.7 0.1 1.7 27.4 4.7 4.4 0.3 0.1 6.5 3.4 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SKI ENSG00000157933 "SKI proto-oncogene" P12755 1 2228319-2310213 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Craniosynostosis, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010449, HPA066567" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "CAB010449: AB_2187342, HPA066567: AB_2685692" "unprognostic (3.99e-2)" "unprognostic (3.81e-2)" "unprognostic (1.44e-1)" "unprognostic (5.42e-2)" "unprognostic (4.66e-2)" "unprognostic (7.32e-2)" "unprognostic (1.88e-1)" "unprognostic (9.14e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "unprognostic (4.94e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-3)" "unprognostic (1.88e-1)" "unprognostic (7.82e-2)" "unprognostic (9.69e-2)" "unprognostic (5.24e-3)" 38.3 14.3 22.0 14.1 20.9 11.5 31.5 59.5 24.2 37.5 3.4 34.6 9.3 42.0 8.3 23.5 34.1 14.6 34.4 24.1 11.0 23.6 24.3 33.9 11.6 20.1 16.9 36.4 13.1 7.3 23.0 13.9 17.2 26.8 7.0 5.1 25.2 19.8 22.1 38.6 24.1 16.8 17.1 22.9 22.6 13.2 19.4 8.7 25.4 11.7 10.2 30.8 29.2 15.7 18.3 10.4 24.5 23.9 40.0 23.8 16.1 26.7 14.8 16.3 11.9 15.8 13.7 11.5 19.5 34.4 6.8 21.0 13.8 21.6 15.0 12.7 30.0 29.0 16.4 22.5 26.7 16.5 29.8 25.8 11.8 24.5 18.2 30.0 20.2 4.8 16.6 8.6 20.2 11.6 2.0 18.1 24.8 12.0 19.8 9.1 15.5 9.6 13.9 7.0 35.0 22.9 26.0 22.9 26.7 15.6 7.7 20.9 36.9 27.7 17.5 39.6 21.1 6.7 5.2 10.5 14.8 28.2 11.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 22.0 20.9 59.5 24.2 24.1 11.0 20.1 16.9 17.2 17.1 19.4 15.7 44.2 9.6 12.6 18.9 18.8 47.0 13.1 7.0 32.5 8.9 20.3 25.8 12.7 11.5 6.7 7.3 0.0 7.3 32.2 7.3 1.9 8.2 0.8 10.1 28.9 34.3 6.0 14.7 22.6 6.9 15.5 35.5 9.7 18.5 13.3 6.4 33.9 23.0 13.7 11.8 24.1 14.3 0.0 16.4 29.5 5.0 49.7 28.9 16.0 48.7 9.4 11.1 12.3 11.6 11.4 13.0 9.4 55.3 16.9 14.9 8.1 6.0 4.0 4.4 46.0 36.2 37.3 4.7 12.8 32.2 45.0 16.3 33.4 6.7 10.7 11.4 SLC17A7 "BNPI, VGLUT1" ENSG00000104888 "Solute carrier family 17 member 7" Q9P2U7 19 49429401-49442360 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "brain: 405.4;retina: 315.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 362.7;Cone photoreceptor cells: 369.1;Excitatory neurons: 107.8;Rod photoreceptor cells: 358.0" "Cancer enriched" "Detected in some" 6 "glioma: 7.5" "Group enriched" "Detected in many" 7 "amygdala: 176.7;basal ganglia: 243.4;cerebral cortex: 289.7;hippocampal formation: 405.4;white matter: 169.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 20.8;K-562: 7.0;REH: 4.0;SCLC-21H: 4.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 201.2;cerebellum: 204.6;cerebral cortex: 339.5;hippocampal formation: 471.2" "CAB037183, HPA050458, HPA063679" Enhanced Supported NA NA "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB037183: AB_261840, HPA050458: AB_2681134, HPA063679: AB_2685086" "unprognostic (1.79e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (1.52e-2)" "unprognostic (9.12e-2)" "unprognostic (3.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.32e-2)" "unprognostic (6.61e-2)" "unprognostic (4.26e-12)" "unprognostic (8.36e-4)" "unprognostic (4.27e-1)" "unprognostic (1.35e-2)" "unprognostic (6.17e-3)" 5.7 1.4 176.7 0.2 243.4 0.0 3.0 32.2 289.7 2.0 0.0 1.5 0.4 1.2 0.6 1.1 2.2 0.9 2.8 405.4 0.0 1.0 0.3 0.6 1.0 31.7 0.8 0.6 0.6 0.6 1.6 0.1 37.8 0.5 0.5 315.8 1.2 0.3 1.7 2.2 1.5 0.6 0.0 0.1 0.9 2.3 0.0 0.3 2.3 2.5 0.6 1.6 1.8 169.9 0.0 0.3 0.2 0.4 1.6 0.3 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.3 0.5 1.2 0.1 1.9 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.1 0.3 0.0 0.3 0.0 0.3 7.0 1.0 0.0 0.2 0.0 0.1 0.0 0.3 0.3 4.0 0.1 0.1 0.0 0.0 4.9 0.4 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.3 2.3 0.9 0.0 0.4 0.3 0.3 0.6 2.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.7 243.4 32.2 289.7 405.4 0.0 31.7 0.8 37.8 0.0 0.0 169.9 1.9 0.0 0.0 9.4 0.0 1.3 0.2 0.0 0.0 362.7 0.5 0.8 3.2 0.0 0.0 0.0 369.1 0.1 0.0 0.2 0.0 0.0 5.6 0.0 0.0 1.7 0.0 0.0 107.8 0.0 0.1 5.5 0.0 0.1 0.0 0.1 0.0 0.0 0.3 11.8 3.4 0.0 0.0 0.0 1.3 0.5 6.5 0.3 1.8 11.2 0.0 22.6 0.0 6.0 8.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 358.0 6.6 0.4 4.3 3.5 4.4 0.6 0.6 0.0 0.1 0.0 0.3 0.1 SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 216.6;Extravillous trophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1046.6" "Lineage enriched" "Detected in all" 26 "granulocytes: 1046.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" 76.4 95.8 10.2 22.3 10.2 53.4 50.4 13.0 14.8 25.4 4.5 59.7 13.1 37.3 15.9 25.3 34.5 44.2 119.7 10.1 12.2 17.8 57.9 33.1 25.9 13.2 10.2 12.9 91.2 22.8 22.6 58.8 15.3 16.5 17.8 21.1 35.6 19.3 144.5 53.0 17.2 46.2 9.5 14.5 53.7 14.9 10.7 81.3 30.7 100.7 17.0 32.8 17.7 10.8 85.3 84.2 58.5 95.1 87.8 8.1 347.1 61.2 24.0 83.6 57.4 91.8 34.8 171.2 60.8 18.5 51.7 103.8 105.2 72.8 51.9 97.6 97.2 150.5 57.8 122.5 14.1 170.3 139.7 10.9 18.4 123.0 42.7 171.6 216.0 137.2 205.4 100.1 46.9 94.0 142.0 114.4 89.0 218.4 55.4 94.0 117.8 208.9 49.1 49.5 75.0 97.0 18.4 58.9 43.9 61.5 80.7 107.1 333.1 46.4 74.8 62.6 117.7 67.0 93.8 221.9 28.8 136.8 57.1 21.9 12.1 1046.6 5.1 38.8 4.2 4.4 2.7 3.9 6.8 2.4 1.1 2.4 1.8 3.1 32.5 40.0 8.2 6.6 10.2 10.2 13.0 14.8 10.1 12.2 13.2 10.2 15.3 9.5 10.7 10.8 64.2 0.0 10.5 1.3 4.0 10.7 9.0 4.1 2.2 10.9 20.2 30.1 46.4 17.2 6.0 7.3 14.6 216.6 5.7 3.0 3.9 24.2 0.5 4.3 3.5 31.7 31.2 49.2 18.4 56.7 224.6 40.0 26.5 11.2 8.2 25.4 25.7 16.7 63.6 5.0 25.4 2.9 79.3 37.0 13.3 2.8 32.9 19.2 35.6 16.9 8.3 4.3 0.0 5.0 2.6 61.9 3.4 53.8 14.2 18.2 0.7 0.9 6.9 11.9 92.1 21.0 22.5 0.4 11.0 4.6 15.6 42.0 3.2 4.1 6.2 9.8 SLC2A4RG "GEF, HDBP1, Si-1-2, Si-1-2-19" ENSG00000125520 "SLC2A4 regulator" Q9NR83 20 63739776-63744050 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 150.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.2;Proximal tubular cells: 160.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063050 Approved "Nuclear speckles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA063050: AB_2684930" "unprognostic (2.89e-2)" "unprognostic (2.32e-1)" "unprognostic (1.84e-2)" "unprognostic (5.78e-2)" "unprognostic (2.07e-3)" "unprognostic (6.48e-3)" "unprognostic (2.70e-1)" "unprognostic (1.96e-2)" "unprognostic (1.31e-1)" "unprognostic (3.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-3)" "unprognostic (3.22e-1)" 59.4 37.9 8.8 3.1 8.6 10.2 45.0 7.3 12.8 42.0 7.7 55.5 1.6 39.2 4.2 47.7 35.0 3.3 60.5 8.3 8.4 67.8 150.6 30.9 5.0 8.4 8.2 45.8 28.4 5.6 23.0 2.8 7.6 50.1 1.5 2.3 27.3 10.5 88.2 60.8 25.6 3.3 8.6 35.5 33.4 24.2 8.2 6.3 32.1 18.7 3.0 50.2 40.6 8.6 20.5 26.4 12.2 11.0 7.6 14.9 11.9 16.6 16.4 43.8 15.2 49.0 34.0 4.3 23.1 12.1 18.9 24.1 6.1 20.0 7.6 13.5 11.0 4.3 19.4 25.8 16.2 10.5 8.9 17.4 29.0 11.8 9.5 8.7 12.8 3.9 15.8 4.7 21.3 37.0 5.9 29.8 5.3 21.9 59.6 29.4 21.8 10.5 17.3 7.8 10.8 19.0 35.4 16.0 4.5 4.6 37.9 33.7 11.0 43.4 22.7 25.2 13.1 12.8 27.0 7.3 18.1 12.4 11.8 0.0 0.0 0.2 0.9 0.0 0.4 0.1 0.9 0.5 0.1 0.0 0.7 0.7 0.0 0.3 0.1 0.2 1.1 0.1 8.8 8.6 7.3 12.8 8.3 8.4 8.4 8.2 7.6 8.6 8.2 8.6 35.9 9.6 21.2 21.5 16.0 24.5 25.0 19.3 19.4 10.1 44.7 61.5 21.3 37.1 11.2 42.3 10.4 30.7 60.1 18.3 78.2 8.2 9.2 16.3 57.1 22.2 2.4 55.4 5.5 10.3 16.6 49.7 12.8 32.4 3.8 52.6 19.6 116.2 14.7 10.1 4.5 17.5 14.2 13.5 12.7 4.3 28.9 14.6 3.6 5.6 11.7 33.5 13.4 8.0 7.1 20.3 7.8 34.6 16.9 14.9 10.5 160.8 6.1 6.5 32.9 26.1 32.9 1.1 6.4 29.3 37.8 8.6 46.3 77.0 15.0 18.3 SLC35A1 "CMPST, hCST" ENSG00000164414 "Solute carrier family 35 member A1" P78382 6 87470623-87512336 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 103.0;Inhibitory neurons: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (3.04e-2)" "unprognostic (1.93e-1)" "unprognostic (6.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.82e-1)" "unprognostic (4.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.58e-2)" "unprognostic (3.01e-3)" "unprognostic (7.26e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (2.70e-6)" "unprognostic (2.85e-1)" "unprognostic (8.51e-2)" "unprognostic (5.48e-2)" "unprognostic (1.04e-1)" 16.4 24.0 24.6 15.6 25.4 11.2 30.9 28.3 31.6 27.8 28.5 39.6 18.8 24.9 22.1 13.9 20.2 19.5 16.0 26.0 25.5 21.2 32.9 37.6 17.9 24.3 24.1 23.1 15.8 23.7 18.9 19.7 24.4 36.8 47.6 14.4 31.6 16.5 13.8 24.9 21.5 22.0 24.5 19.0 29.2 13.2 24.9 16.3 16.9 15.7 16.3 21.5 16.7 25.4 4.8 11.5 20.4 24.1 54.4 49.3 16.4 13.9 12.2 11.4 15.6 9.9 86.0 17.6 16.8 17.3 31.7 18.5 24.8 11.3 14.6 25.3 18.4 20.0 14.7 17.8 35.7 26.3 13.3 25.3 26.6 13.5 26.1 26.8 27.5 25.5 26.1 28.4 17.0 44.6 7.3 39.6 11.0 60.4 18.6 22.4 19.9 19.0 35.6 20.4 13.3 14.6 25.7 47.4 23.2 23.3 42.2 53.0 26.0 16.4 11.1 18.2 11.3 21.1 32.7 6.5 13.7 46.2 23.7 52.1 54.1 22.8 17.5 42.8 27.1 17.8 18.7 21.5 46.9 16.7 23.7 22.3 13.2 17.5 44.2 17.3 26.8 36.9 24.6 25.4 28.3 31.6 26.0 25.5 24.3 24.1 24.4 24.5 24.9 25.4 14.7 44.8 33.6 19.2 11.7 14.8 18.1 37.1 18.8 6.2 23.6 16.6 6.2 20.0 25.5 16.5 12.5 25.0 16.1 27.1 7.9 10.1 10.6 6.3 9.9 15.8 15.0 8.2 103.0 8.9 19.7 19.2 13.3 6.8 21.6 14.2 42.8 20.7 15.6 11.8 87.2 73.5 48.8 28.2 11.1 7.1 16.4 15.8 21.4 24.4 27.4 17.3 16.5 42.3 26.9 11.5 19.0 19.2 9.4 17.5 14.5 11.3 25.4 7.0 19.7 8.9 16.9 9.6 14.2 9.0 14.8 27.5 14.9 12.5 32.7 8.9 SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61083733 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 178.2;Excitatory neurons: 98.8;Hofbauer cells: 100.3;Inhibitory neurons: 77.4;Late spermatids: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" 7.6 9.1 6.0 4.7 6.6 2.9 7.4 6.1 9.5 7.3 8.9 4.8 3.1 5.1 13.2 3.3 5.6 9.9 3.7 6.9 6.5 12.0 6.3 8.6 7.8 5.4 6.0 5.8 3.4 21.3 7.2 9.6 6.0 5.1 6.6 7.5 5.9 3.9 2.1 2.9 3.5 5.3 5.0 6.6 3.8 5.0 7.4 5.0 6.3 3.0 4.8 7.0 5.0 6.7 16.2 21.5 6.8 12.3 68.7 25.3 4.9 11.6 34.5 10.7 10.2 5.4 41.0 4.0 19.2 10.6 22.5 13.5 6.8 11.9 9.8 6.0 3.2 6.7 8.6 14.2 22.7 3.7 12.1 19.9 4.9 10.5 12.2 43.2 14.3 6.8 9.3 8.4 37.5 9.2 6.6 8.4 4.0 9.5 14.3 1.6 20.1 11.9 30.7 8.5 3.3 3.0 9.9 7.0 19.1 9.3 10.4 5.8 15.6 16.4 7.1 20.0 6.5 1.6 4.9 1.6 34.0 3.0 13.1 0.0 6.6 0.1 1.7 7.1 2.2 2.2 3.1 2.4 3.6 2.0 2.7 3.4 0.2 0.8 4.5 4.4 4.5 2.8 6.0 6.6 6.1 9.5 6.9 6.5 5.4 6.0 6.0 5.0 7.4 6.7 6.8 22.4 6.7 31.6 6.0 5.2 11.4 14.6 8.0 19.7 7.2 7.5 4.3 7.2 10.0 5.5 22.9 5.6 4.9 2.6 1.9 5.3 178.2 13.0 11.0 7.2 4.2 3.4 98.8 2.8 9.4 11.2 5.1 6.2 6.3 7.3 4.2 4.6 100.3 5.0 77.4 3.1 6.1 24.8 10.0 124.4 10.8 26.2 5.4 20.6 6.4 11.7 2.1 54.3 30.8 7.4 1.9 6.0 5.8 6.6 3.3 23.1 40.4 24.9 0.0 12.3 9.1 16.6 11.5 6.4 2.8 6.7 7.8 5.0 2.8 6.9 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.8;Bipolar cells: 41.7;Club cells: 27.4;Ionocytes: 16.2;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 28.8;OE19: 24.2;RT4: 101.4;WM-115: 23.7" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" 0.1 0.2 1.0 0.9 4.4 0.0 3.2 2.2 1.9 1.2 0.1 5.5 3.5 1.0 2.5 1.9 0.5 1.4 1.5 0.2 2.0 0.1 0.9 3.3 0.0 0.6 2.3 0.0 0.2 0.0 0.1 0.9 0.9 7.6 6.8 4.8 27.7 2.2 0.0 5.6 5.7 0.4 0.3 0.1 1.5 0.3 5.7 0.2 0.3 0.1 0.1 14.7 1.4 0.4 0.0 2.9 0.1 0.5 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.9 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 28.8 0.0 3.3 2.7 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 24.2 1.9 0.2 0.0 0.0 0.0 101.4 1.0 1.2 0.5 0.1 0.1 1.7 0.5 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.4 2.2 1.9 0.2 2.0 0.6 2.3 0.9 0.3 5.7 0.4 0.1 0.0 1.8 0.0 0.0 3.8 5.0 22.8 0.0 41.7 5.3 1.5 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 4.3 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.0 2.7 0.0 2.2 2.2 0.0 0.2 0.0 0.4 1.7 16.2 0.0 0.6 0.0 9.6 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 1.8 0.0 0.4 0.0 1.5 0.0 0.1 41.6 2.0 0.0 0.0 0.8 0.0 0.1 3.8 2.4 0.0 0.2 0.1 0.5 4.5 SNCAIP SYPH1 ENSG00000064692 "Synuclein alpha interacting protein" Q9Y6H5 5 122311354-122464219 "Disease related genes, Predicted intracellular proteins" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.5;ovary: 37.5" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Early spermatids: 68.1;Endometrial stromal cells: 56.9;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 7.6" "Lineage enriched" "Detected in single" 50 "granulocytes: 7.6" "Cell line enhanced" "Detected in some" "AF22: 5.2;BJ hTERT+: 5.1;HBF TERT88: 3.2;OE19: 3.0;RPMI-8226: 5.2" "Low region specificity" "Detected in all" HPA064687 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Cytoplasmic bodies" Nucleoplasm "HPA064687: AB_2685324" "unprognostic (7.28e-3)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (6.56e-2)" "unprognostic (2.18e-2)" "unprognostic (1.56e-1)" "unprognostic (1.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.95e-2)" "unprognostic (3.73e-1)" "unprognostic (3.52e-2)" "unprognostic (3.00e-1)" "unprognostic (5.98e-2)" "unprognostic (1.82e-3)" "unprognostic (5.77e-2)" "unprognostic (2.82e-1)" "unprognostic (2.44e-1)" 3.1 1.0 2.5 2.5 7.8 0.3 1.4 7.2 3.0 17.2 10.1 1.1 1.2 19.5 1.3 0.6 5.1 2.5 1.3 2.9 2.9 1.7 0.1 1.2 2.1 4.6 5.2 37.5 0.5 0.2 1.2 2.0 4.2 1.9 1.1 0.5 0.4 2.7 0.3 1.8 0.7 12.0 3.0 5.2 1.0 4.5 5.7 1.7 0.8 1.6 1.5 4.1 2.5 4.3 0.0 0.0 5.2 0.1 0.0 0.0 0.1 2.2 5.1 0.8 0.4 0.0 0.1 0.1 0.1 2.2 0.4 0.0 2.1 0.3 3.2 1.9 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.2 0.0 0.6 0.1 0.0 0.8 0.0 0.0 0.0 0.1 2.5 3.0 0.0 0.1 0.0 5.2 0.2 0.6 0.9 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.5 0.3 0.4 0.0 0.0 0.2 0.2 0.0 0.1 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.5 7.8 7.2 3.0 2.9 2.9 4.6 5.2 4.2 3.0 5.7 4.3 6.1 0.0 0.5 84.5 0.0 1.8 3.8 0.5 1.8 0.4 0.4 1.0 0.8 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 6.1 68.1 4.6 56.9 7.1 0.0 0.0 21.8 0.0 0.1 5.6 0.0 1.4 1.3 0.1 18.9 0.2 0.3 0.0 62.8 0.0 0.0 0.8 0.4 16.6 5.3 0.6 1.8 13.1 0.0 0.5 0.0 30.7 1.9 0.4 0.7 5.7 0.0 3.0 0.0 0.3 14.9 0.0 0.0 0.5 2.3 4.1 2.1 1.8 2.7 0.1 0.4 0.1 0.2 1.5 SOBP FLJ10159 ENSG00000112320 "Sine oculis binding protein homolog" A7XYQ1 6 107490106-107661306 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 175.3;Excitatory neurons: 260.1;Granulosa cells: 149.3;Inhibitory neurons: 287.7;Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enriched" "Detected in single" 13 "B-cells: 1.3" "Cell line enhanced" "Detected in many" "AF22: 10.5;AN3-CA: 13.9;ASC diff: 12.9;HDLM-2: 9.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029242 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA029242: AB_10603340" "unprognostic (7.11e-2)" "unprognostic (1.35e-3)" "unprognostic (9.01e-2)" "unprognostic (2.04e-3)" "unprognostic (3.09e-1)" "unprognostic (1.12e-1)" "unprognostic (3.80e-2)" "unprognostic (5.63e-2)" "unprognostic (9.84e-2)" "unprognostic (5.35e-3)" "prognostic favorable (1.55e-5)" "unprognostic (6.64e-2)" "unprognostic (2.00e-3)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-3)" 4.5 6.6 12.4 1.7 14.5 0.0 3.4 9.0 16.9 6.2 0.4 14.6 1.2 5.6 2.0 2.0 4.3 2.7 10.9 15.3 8.2 3.4 1.6 2.4 0.9 6.7 9.1 10.8 1.4 3.1 9.4 2.3 6.2 8.2 1.3 5.3 10.4 2.6 16.7 1.2 3.2 3.9 6.5 1.9 4.8 4.2 9.5 2.7 4.2 5.9 1.1 11.9 4.4 11.4 0.0 0.3 10.5 13.9 12.9 4.9 1.2 0.0 0.0 0.3 0.6 0.0 0.0 5.7 0.3 0.0 0.9 0.0 7.0 0.2 0.2 9.0 6.8 0.6 0.0 6.8 1.6 3.0 0.5 5.2 0.0 5.1 0.0 1.1 4.2 2.6 0.0 0.3 0.0 2.9 1.3 0.3 2.5 0.3 0.9 3.1 1.3 0.0 0.0 0.2 3.3 5.6 1.2 0.0 0.1 0.4 0.4 2.0 0.0 3.3 1.1 5.7 0.5 2.6 0.5 3.5 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 14.5 9.0 16.9 15.3 8.2 6.7 9.1 6.2 6.5 9.5 11.4 6.0 3.2 9.8 175.3 9.2 0.5 10.3 11.4 3.4 40.4 0.5 7.4 19.4 17.2 6.1 23.9 0.0 0.2 1.8 0.2 0.0 2.5 96.2 0.6 15.8 4.4 10.8 5.3 260.1 0.2 0.7 23.6 3.1 0.4 0.0 149.3 5.3 1.4 3.0 92.5 287.7 0.1 4.1 9.6 4.1 61.4 45.1 1.8 3.6 51.5 0.1 7.6 0.0 263.9 278.8 0.4 0.0 48.9 0.2 9.3 0.0 11.9 10.9 10.1 26.3 42.8 21.0 61.2 5.6 0.6 0.9 0.1 1.3 13.3 0.2 1.0 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPTAN1 ENSG00000197694 "Spectrin alpha, non-erythrocytic 1" Q13813 9 128552558-128633662 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 296.6;Cone photoreceptor cells: 310.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004581, HPA007927" Enhanced Approved Vesicles,Microtubules NA NA 1600000 "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Microtubules" "CAB004581: AB_671135, HPA007927: AB_1857435" "unprognostic (1.46e-2)" "unprognostic (2.73e-2)" "unprognostic (1.56e-1)" "unprognostic (9.06e-2)" "unprognostic (3.24e-1)" "unprognostic (4.02e-2)" "unprognostic (2.56e-3)" "unprognostic (2.20e-1)" "unprognostic (1.81e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.84e-12)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (4.18e-3)" "unprognostic (2.19e-3)" 48.8 31.4 81.7 38.6 85.0 28.1 36.6 54.4 99.7 39.4 0.4 47.3 24.7 57.1 32.9 36.8 54.0 32.5 65.7 90.9 43.5 34.6 22.8 55.1 38.5 142.7 49.6 51.6 24.0 47.1 32.5 57.1 155.0 32.7 36.3 103.1 31.9 46.5 23.9 69.4 34.9 58.8 65.6 44.3 31.1 44.9 61.5 45.4 38.4 22.3 38.0 40.0 36.4 55.3 108.1 116.9 75.2 83.4 107.6 121.0 61.5 90.2 75.2 99.4 74.1 167.3 74.6 94.3 78.3 137.0 69.8 193.3 80.7 90.4 61.1 53.2 47.9 15.9 324.4 94.4 61.3 70.9 51.0 58.3 71.6 166.3 55.8 83.9 134.4 87.2 9.1 107.6 98.6 74.6 136.3 29.5 96.1 125.9 72.1 91.0 90.2 59.7 80.2 91.1 58.1 91.1 296.1 40.3 42.9 91.8 70.0 19.8 232.5 68.5 102.2 100.0 71.2 65.3 82.6 51.8 83.5 31.5 65.9 3.3 1.6 3.9 9.7 1.3 13.5 6.3 12.4 9.2 2.4 5.8 7.6 7.9 1.5 7.1 1.2 3.0 15.3 5.8 81.7 85.0 54.4 99.7 90.9 43.5 142.7 49.6 155.0 65.6 61.5 55.3 144.9 70.5 27.5 123.7 56.3 37.3 27.8 34.3 25.6 296.6 69.8 83.2 68.5 68.6 33.9 101.2 310.6 27.5 112.6 145.4 7.9 67.6 18.0 108.2 71.4 103.8 56.9 13.7 159.5 59.2 16.0 77.8 76.5 87.5 12.0 47.9 96.8 36.2 29.2 124.5 183.8 54.1 30.5 22.2 29.4 40.5 85.1 32.8 35.6 74.9 24.4 97.7 48.4 87.4 17.4 102.2 93.0 94.8 70.5 45.9 62.4 22.8 71.3 156.5 26.3 53.0 60.0 33.0 44.5 43.7 45.5 18.2 95.4 22.0 73.6 65.7 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 39.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 19.3;Fibroblasts: 27.0;Leydig cells: 18.0;Peritubular cells: 15.8;Skeletal myocytes: 32.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 26.9;BJ: 22.7;fHDF/TERT166: 27.5;hTERT-RPE1: 23.2;U-87 MG: 27.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Yes NA 88000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" 13.1 2.2 2.6 3.6 4.6 0.1 8.8 3.0 2.1 23.0 1.8 33.6 1.9 39.7 3.9 5.7 17.0 12.9 17.6 1.8 2.1 3.6 1.7 9.1 1.3 3.9 2.6 14.5 1.8 0.3 17.6 1.9 4.0 8.8 2.8 1.1 3.4 12.8 3.6 5.6 8.7 20.1 2.2 11.1 9.8 2.6 3.6 2.0 3.8 2.8 0.5 10.6 15.9 2.1 0.1 1.4 0.5 0.0 3.3 26.9 0.0 22.7 5.5 3.7 4.6 0.4 0.0 1.2 0.3 27.5 1.1 0.0 0.0 0.0 1.9 0.1 0.3 5.6 1.5 0.0 5.2 0.1 9.6 12.3 0.0 5.4 0.0 23.2 0.0 0.7 0.2 0.3 0.6 0.1 0.1 0.5 0.9 0.0 0.2 0.7 1.2 0.3 2.5 0.0 2.9 0.4 0.4 0.0 0.5 0.5 0.4 1.2 7.9 1.0 1.3 1.1 3.8 0.4 0.0 0.1 27.8 0.3 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.6 3.0 2.1 1.8 2.1 3.9 2.6 4.0 2.2 3.6 2.1 3.5 3.2 0.6 4.2 0.3 1.9 0.3 0.3 0.0 5.3 0.8 1.1 2.8 0.0 0.1 0.0 2.1 0.1 0.4 0.8 1.9 0.1 0.6 1.5 19.3 3.3 0.0 0.0 1.5 0.0 0.1 27.0 2.0 0.9 0.0 0.5 2.2 0.0 1.2 3.3 1.1 0.4 0.0 1.0 3.8 1.3 18.0 2.0 1.8 2.8 0.7 2.1 0.0 0.0 0.3 0.1 0.3 15.8 0.3 0.3 4.6 0.2 0.7 1.9 0.0 32.1 6.8 0.9 1.1 0.4 1.8 0.0 0.5 0.9 1.4 0.2 SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 79.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 140.8;Leydig cells: 185.8;Peritubular cells: 267.4;Skeletal myocytes: 139.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.4;naive B-cell: 16.9" "Lineage enriched" "Detected in many" 19 "B-cells: 57.4" "Group enriched" "Detected in many" 4 "ASC diff: 24.4;hTERT-RPE1: 91.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 19: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane" Nucleoplasm "HPA066432: AB_2685669" "unprognostic (4.82e-2)" "unprognostic (1.63e-1)" "unprognostic (2.03e-1)" "unprognostic (6.49e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-1)" "unprognostic (6.11e-2)" "unprognostic (1.44e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (2.77e-5)" "unprognostic (2.64e-3)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" 21.3 10.7 18.0 6.4 26.5 0.1 20.1 26.2 15.4 39.5 8.6 21.2 4.4 23.9 17.8 18.3 25.2 21.9 46.0 16.1 30.1 6.1 1.4 8.9 7.0 26.5 29.1 33.8 8.0 3.2 3.8 4.6 27.9 22.4 12.7 2.9 9.4 34.4 60.7 4.4 7.7 24.3 31.5 8.7 7.7 8.3 21.5 8.7 17.1 79.0 12.1 19.2 15.4 38.4 0.8 1.6 4.0 0.0 24.4 14.5 0.2 6.9 10.8 1.1 3.1 0.1 9.5 0.0 1.8 11.0 6.0 3.0 0.0 0.5 2.1 0.1 0.0 0.0 0.1 0.0 2.9 0.1 0.0 9.3 1.0 3.5 0.8 91.6 0.4 0.0 0.0 0.1 8.4 1.9 0.6 1.9 7.9 0.6 2.7 0.3 10.7 3.2 2.4 8.3 0.4 6.3 2.7 0.6 7.0 4.0 0.9 0.3 3.0 2.5 1.8 3.4 1.8 0.3 1.2 0.2 5.3 0.0 8.6 0.0 0.0 2.7 0.0 0.0 0.5 57.4 0.0 0.0 0.1 16.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.7 18.0 26.5 26.2 15.4 16.1 30.1 26.5 29.1 27.9 31.5 21.5 38.4 10.8 3.2 3.2 39.2 30.7 13.6 23.1 21.6 30.1 2.1 21.8 89.2 95.4 10.0 14.8 18.4 0.0 74.0 1.4 36.0 5.9 11.4 4.0 12.4 52.1 10.2 4.9 1.3 3.5 7.1 7.5 140.8 3.6 6.0 0.0 10.7 9.7 0.2 15.3 6.7 5.8 10.1 0.0 0.6 11.1 5.8 185.8 6.6 19.6 18.7 18.6 41.2 0.0 41.7 18.4 2.8 7.3 267.4 41.2 19.4 0.6 3.1 7.9 2.7 39.5 139.9 56.3 0.7 3.8 7.7 7.1 27.8 2.1 30.7 7.7 24.7 ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 270.0;Paneth cells: 214.3;Syncytiotrophoblasts: 962.5" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 111.9;neutrophil: 71.8;plasmacytoid DC: 93.7" "Group enriched" "Detected in many" 12 "dendritic cells: 93.7;granulocytes: 111.9" "Cell line enhanced" "Detected in all" "SK-MEL-30: 234.7;WM-115: 515.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" NA NA 15000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049827: AB_2680900" "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" 23.4 117.1 25.2 14.4 41.2 19.0 19.5 43.5 28.9 29.2 36.5 58.1 4.2 16.3 87.6 70.7 19.2 23.9 60.0 24.3 28.7 41.0 28.4 38.2 10.0 42.3 41.3 111.3 13.7 1.7 15.7 35.3 39.5 22.6 66.4 10.8 44.2 16.0 6.1 16.7 12.3 19.0 31.9 41.5 13.3 42.2 37.6 6.3 14.7 7.7 22.7 49.3 33.8 57.2 26.4 21.4 17.0 13.6 46.8 39.4 38.5 30.2 56.6 26.5 18.2 11.4 44.5 7.0 21.9 47.0 88.0 37.1 34.0 19.2 20.0 27.7 9.7 62.8 52.7 13.4 29.9 78.8 126.1 31.5 30.7 39.9 60.9 47.7 34.6 27.5 41.4 18.8 32.2 107.3 25.7 76.5 10.2 166.2 136.6 25.8 50.3 3.3 6.0 74.1 29.5 18.4 32.8 193.5 234.7 10.6 66.3 52.2 13.2 61.7 14.2 44.1 56.2 2.0 4.3 4.0 28.5 118.7 515.8 111.9 5.3 0.7 5.2 8.7 4.8 0.4 1.7 3.3 20.6 0.1 0.6 2.6 71.8 4.7 3.8 93.7 0.3 6.4 25.2 41.2 43.5 28.9 24.3 28.7 42.3 41.3 39.5 31.9 37.6 57.2 10.3 9.6 0.6 17.0 1.9 10.6 6.6 23.0 0.6 4.0 12.8 6.7 25.9 5.7 23.1 31.3 10.4 115.9 37.5 149.2 49.0 6.1 1.5 3.2 9.8 15.0 5.3 3.4 16.3 6.6 72.3 43.2 2.0 10.2 41.9 270.0 31.8 11.9 17.8 5.0 17.5 115.7 16.2 5.9 14.9 7.2 76.1 11.2 78.2 3.7 9.5 5.4 18.6 5.0 83.3 5.3 214.3 93.6 6.7 16.5 0.0 3.9 5.5 10.0 13.1 4.3 43.1 1.5 17.4 0.7 6.7 962.5 8.4 36.8 23.2 41.1 STARD9 "KIAA1300, KIF16A" ENSG00000159433 "StAR related lipid transfer domain containing 9" Q9P2P6 15 42575606-42720998 "Metabolic proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;Early spermatids: 52.8;Excitatory neurons: 39.3;Oligodendrocytes: 80.9;Rod photoreceptor cells: 57.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA014562 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA014562: AB_10603033" "unprognostic (2.69e-2)" "unprognostic (2.93e-1)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (6.74e-2)" "unprognostic (5.54e-5)" "unprognostic (7.45e-2)" "unprognostic (1.59e-1)" "unprognostic (1.01e-1)" "unprognostic (1.94e-2)" "unprognostic (1.91e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-3)" "unprognostic (1.53e-2)" "unprognostic (3.92e-2)" "unprognostic (3.13e-1)" "unprognostic (1.83e-3)" 6.2 0.5 1.5 1.2 5.2 0.6 4.3 3.1 3.3 5.9 2.4 9.1 1.3 5.3 3.0 2.2 3.3 2.4 3.3 1.3 1.6 0.8 0.4 4.5 1.2 4.7 2.5 6.0 0.4 0.4 0.8 3.9 2.8 2.6 2.8 12.9 1.5 3.2 2.5 2.6 3.2 4.8 1.0 2.0 3.2 8.5 4.4 3.5 1.7 3.5 1.1 4.4 5.0 9.9 0.9 0.5 5.9 2.3 3.1 4.5 0.3 1.0 1.3 1.8 2.7 0.0 0.0 0.7 0.1 1.1 1.2 0.1 2.0 0.9 2.4 3.5 1.7 0.3 4.3 1.3 1.3 0.9 1.1 2.6 0.4 1.5 1.0 1.5 1.8 2.5 1.6 3.8 1.5 0.0 0.7 0.7 0.9 0.0 1.1 5.1 3.2 1.1 0.7 0.0 1.2 2.9 1.3 0.0 0.4 0.7 0.1 0.4 3.6 2.5 1.9 0.9 2.4 3.8 2.2 1.3 1.0 2.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 5.2 3.1 3.3 1.3 1.6 4.7 2.5 2.8 1.0 4.4 9.9 26.1 12.8 2.8 7.2 2.9 3.6 1.2 0.8 1.2 8.1 0.6 1.0 6.8 0.0 0.7 1.8 52.1 0.2 4.2 0.3 0.0 0.3 52.8 3.5 12.2 19.8 8.4 3.2 39.3 0.0 0.3 15.2 2.6 0.6 2.5 3.6 9.7 0.5 2.8 11.8 33.5 2.8 0.0 2.4 7.7 15.4 24.5 2.3 8.8 24.4 2.4 2.9 11.3 20.1 80.9 0.2 0.0 22.2 2.7 0.9 0.1 0.3 9.1 57.7 19.7 11.8 13.7 3.9 8.0 0.3 3.1 0.3 6.3 7.8 0.4 0.7 SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 39.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 19.6;Hofbauer cells: 22.0;Kupffer cells: 32.0;Macrophages: 11.8;Proximal tubular cells: 46.3;Smooth muscle cells: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 53.3;NB-4: 31.0;U-937: 52.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022745 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" 3.5 0.8 0.0 1.3 0.1 8.1 1.0 0.0 0.2 0.2 0.0 0.5 1.2 0.1 0.1 0.2 0.1 0.5 0.7 0.0 0.2 39.9 5.2 2.6 1.9 0.2 0.2 0.1 0.0 3.4 0.0 0.2 0.3 0.1 0.8 0.0 0.6 0.1 0.0 1.0 1.0 0.7 0.1 7.0 7.8 0.1 0.4 0.9 9.3 0.1 0.6 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 8.7 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.2 0.3 0.1 0.4 0.2 8.4 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 1.5 0.1 3.7 0.0 0.1 1.4 0.0 19.6 0.0 0.5 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 4.3 22.0 0.0 0.0 0.2 8.2 32.0 8.1 0.4 0.0 11.8 0.0 8.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 46.3 1.5 0.0 0.0 0.1 11.2 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.1 SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 129.2;Late spermatids: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008700 Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA008700: AB_1080125" "unprognostic (1.55e-1)" "unprognostic (4.00e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-1)" "unprognostic (4.69e-2)" "unprognostic (5.68e-2)" "unprognostic (3.69e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (3.15e-3)" "unprognostic (9.60e-2)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "unprognostic (5.10e-2)" "unprognostic (3.82e-3)" 6.6 7.2 8.8 7.1 8.5 2.0 6.1 8.9 8.0 8.6 5.5 6.8 3.9 7.4 4.9 9.2 7.1 6.6 6.3 7.8 7.3 6.1 6.2 5.8 7.2 8.3 8.2 8.9 4.1 11.1 4.3 7.4 7.8 8.5 4.4 4.6 7.1 5.2 8.6 14.4 5.7 7.3 6.7 7.4 4.6 11.5 8.0 7.8 3.4 7.3 8.1 8.8 9.2 7.3 8.7 9.1 14.4 20.8 14.5 12.1 7.0 8.8 17.0 12.5 11.3 8.5 6.3 8.9 24.5 9.9 5.0 6.0 17.8 9.8 8.2 5.5 13.8 21.2 5.2 8.0 6.9 7.7 14.6 13.9 7.5 9.3 7.5 22.9 16.3 8.5 4.8 7.9 7.8 7.2 14.8 11.6 4.1 5.6 6.7 15.8 15.5 4.7 8.3 12.8 4.8 7.8 7.0 6.4 8.1 13.1 14.2 5.0 18.1 5.5 7.8 6.0 9.8 6.4 4.5 6.4 6.9 14.9 3.8 2.0 2.0 2.9 1.0 2.4 0.8 0.9 1.2 1.1 1.9 0.8 0.8 1.0 0.4 1.1 2.5 1.1 0.8 1.4 8.8 8.5 8.9 8.0 7.8 7.3 8.3 8.2 7.8 6.7 8.0 7.3 3.3 0.0 3.7 28.7 4.9 3.1 2.1 2.9 6.8 4.2 3.5 3.0 4.0 1.5 4.6 3.7 8.4 7.8 3.1 3.5 1.9 4.4 129.2 4.5 6.2 5.1 1.2 2.5 25.9 3.0 3.5 6.0 4.6 8.5 3.8 3.8 10.8 5.4 12.4 1.7 22.2 2.2 0.0 9.4 6.3 115.9 5.0 8.7 0.0 32.8 7.8 2.7 4.1 17.6 16.8 4.1 1.3 6.8 4.0 2.0 5.7 5.8 5.7 4.8 0.0 3.0 4.5 8.7 5.3 8.9 6.5 7.0 7.1 7.6 3.0 1.3 TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 126.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 55.2;Horizontal cells: 48.8;Leydig cells: 43.8;Muller glia cells: 88.3;Oligodendrocytes: 46.5;Peritubular cells: 39.1;Skeletal myocytes: 48.3;Smooth muscle cells: 38.7" "Cancer enriched" "Detected in many" 10 "glioma: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 83.8;BJ hTERT+ SV40 Large T+ RasG12V: 75.1;GAMG: 115.3;hTEC/SVTERT24-B: 83.8;LHCN-M2: 72.0;SCLC-21H: 210.1;U-87 MG: 78.9" "Low region specificity" "Detected in many" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA051507: AB_2681512, HPA065080: AB_2685419" "unprognostic (1.09e-2)" "unprognostic (4.36e-2)" "unprognostic (5.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (4.52e-2)" "unprognostic (2.17e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.18e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (3.53e-4)" "unprognostic (2.62e-1)" "unprognostic (2.28e-2)" "unprognostic (1.35e-3)" 7.7 27.9 72.4 4.3 73.0 0.0 9.1 75.1 126.3 26.3 40.5 18.6 4.0 48.2 18.3 5.5 17.0 11.9 14.0 72.1 84.5 5.0 2.4 6.1 2.3 80.8 77.5 29.0 1.2 1.1 37.4 2.1 82.3 12.3 7.8 23.5 3.5 13.2 3.7 1.8 8.3 29.9 74.5 5.8 6.5 3.1 77.2 5.1 3.8 9.9 1.4 9.7 15.6 96.0 0.0 0.0 83.8 0.0 36.3 55.5 15.0 12.0 61.9 26.4 75.1 0.0 0.0 0.0 0.0 12.9 115.3 0.0 0.0 1.8 45.5 0.0 0.8 0.3 0.0 0.0 18.2 0.0 0.1 46.6 0.0 83.8 0.1 0.0 27.6 0.0 0.5 0.2 72.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 53.1 0.3 0.0 0.0 210.1 56.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 38.8 1.4 0.6 0.0 0.0 0.0 0.0 78.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 72.4 73.0 75.1 126.3 72.1 84.5 80.8 77.5 82.3 74.5 77.2 96.0 4.8 0.0 1.3 5.9 0.0 2.5 5.3 0.3 1.2 36.4 0.9 19.2 13.6 0.0 0.7 3.7 4.2 1.4 0.1 0.0 5.9 0.2 0.2 1.0 42.9 5.2 0.0 0.0 21.2 0.0 0.7 55.2 0.0 0.7 0.0 19.2 1.8 0.0 0.7 48.8 26.5 0.0 0.0 0.0 4.0 1.8 43.8 0.6 8.8 4.7 0.0 88.3 0.0 19.6 46.5 0.3 0.0 39.1 0.1 1.1 0.0 2.1 0.0 12.9 13.1 48.3 38.7 3.0 1.5 0.8 3.1 0.3 0.5 5.1 0.0 0.8 TDRD3 FLJ21007 ENSG00000083544 "Tudor domain containing 3" Q9H7E2 13 60396457-60573878 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 169.1;granulocytes: 152.3;Inhibitory neurons: 128.9;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034925, HPA067153" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Golgi apparatus, Cytosol" "CAB034925: AB_2240523, HPA067153: AB_2732759" "unprognostic (8.52e-2)" "unprognostic (3.19e-1)" "unprognostic (2.23e-1)" "prognostic favorable (2.77e-4)" "unprognostic (5.21e-2)" "unprognostic (2.62e-1)" "unprognostic (7.37e-2)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (6.18e-3)" "unprognostic (9.62e-2)" "unprognostic (9.95e-2)" "unprognostic (3.68e-2)" "unprognostic (4.40e-2)" "unprognostic (1.27e-3)" 8.8 8.2 14.2 6.8 18.7 5.8 12.0 18.2 16.4 10.6 12.7 9.9 9.5 10.8 9.9 10.4 9.8 9.2 10.7 11.8 16.0 11.4 9.4 12.5 9.1 17.1 15.5 14.0 14.1 10.9 7.7 6.0 16.6 8.0 11.1 10.9 9.3 7.4 16.7 11.3 8.7 9.2 16.0 8.7 11.2 12.3 17.9 11.9 12.0 18.5 9.2 8.1 7.7 21.2 6.7 7.3 15.3 36.7 5.9 13.3 9.5 7.6 8.4 8.7 5.6 4.9 10.9 16.0 3.0 11.1 7.4 8.9 12.6 11.0 9.4 12.5 10.1 30.4 13.7 9.4 12.0 21.3 15.4 8.9 15.4 5.1 15.1 17.9 12.0 13.3 6.7 9.7 9.5 7.4 19.5 11.4 11.7 24.4 5.5 10.1 7.5 11.0 12.0 8.8 13.8 16.4 10.9 13.2 27.9 10.9 6.8 9.3 10.2 5.4 5.6 6.1 8.5 18.8 17.7 13.7 5.0 11.0 16.7 0.3 1.4 1.6 3.2 2.2 2.3 2.2 3.7 3.7 2.1 1.4 3.0 3.8 0.1 2.1 1.7 4.6 4.5 1.3 14.2 18.7 18.2 16.4 11.8 16.0 17.1 15.5 16.6 16.0 17.9 21.2 24.5 22.4 30.0 169.1 13.8 7.9 9.6 9.3 14.8 30.9 10.8 10.2 44.4 11.5 18.2 11.0 54.2 8.8 18.7 11.5 21.5 13.4 20.9 18.8 24.4 15.9 17.4 7.2 101.1 17.8 10.6 18.5 18.3 15.7 152.3 26.1 11.7 8.8 6.9 20.2 128.9 12.8 12.2 9.5 7.8 24.4 19.0 22.2 19.6 69.3 12.2 12.7 20.6 142.7 168.7 10.6 19.2 18.4 14.6 7.1 12.4 12.3 22.8 30.6 6.6 32.9 12.9 38.9 21.6 14.1 6.7 6.7 20.9 30.6 14.0 8.0 TET1 "bA119F7.1, CXXC6, KIAA1676, LCX" ENSG00000138336 "Tet methylcytosine dioxygenase 1" Q8NFU7 10 68560337-68694487 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, DNA-binding, Oxidoreductase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9" "Cell type enhanced" "Detected in many" "Astrocytes: 54.5;Extravillous trophoblasts: 79.9;Oligodendrocyte precursor cells: 44.7;Oligodendrocytes: 45.3;Theca cells: 43.7" "Cancer enriched" "Detected in some" 15 "testis cancer: 10.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;HAP1: 20.4;K-562: 12.0;NTERA-2: 11.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019032, HPA057273" Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nuclear membrane" "HPA019032: AB_1847363, HPA057273: AB_2683391" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "unprognostic (9.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (8.15e-2)" "unprognostic (3.60e-3)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (7.90e-3)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.18e-3)" "unprognostic (2.88e-4)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (9.52e-3)" 0.4 0.2 0.6 0.2 1.2 0.3 0.4 4.9 0.7 0.7 0.8 0.4 0.1 0.9 0.6 0.2 0.5 0.3 0.3 0.3 0.9 0.3 0.2 0.2 0.3 0.9 1.3 0.8 0.2 0.7 0.3 1.2 1.1 0.6 0.3 1.5 1.0 0.3 0.9 0.3 0.2 0.5 1.0 0.3 0.4 0.2 1.1 2.0 0.5 0.3 0.3 0.2 0.4 2.2 0.7 0.8 8.0 9.0 0.8 0.7 17.7 0.4 1.0 0.7 1.2 5.5 0.3 0.0 0.3 0.8 0.1 0.0 20.4 0.0 0.8 0.3 3.3 2.1 0.0 4.9 1.2 1.9 1.0 1.0 0.1 0.5 0.1 1.6 0.1 3.5 12.0 1.4 0.7 0.6 3.3 1.4 11.9 0.0 1.1 3.2 2.5 0.2 0.4 0.8 2.2 3.5 0.4 0.5 1.6 7.9 1.0 1.5 0.3 0.7 1.6 0.0 0.6 0.5 0.6 3.2 0.2 0.0 0.2 0.0 0.0 0.2 0.3 0.0 0.4 0.3 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.2 0.5 0.0 0.6 1.2 4.9 0.7 0.3 0.9 0.9 1.3 1.1 1.0 1.1 2.2 6.3 3.2 6.2 54.5 2.5 1.1 1.8 0.4 5.2 2.5 7.0 9.5 7.2 1.5 2.6 0.0 10.4 21.0 3.0 0.2 0.0 2.7 0.8 3.6 34.2 4.8 13.8 2.5 15.6 0.4 79.9 15.4 1.5 2.9 0.0 13.6 5.7 2.5 3.9 35.3 20.6 0.3 4.1 0.0 0.3 1.7 25.7 0.8 1.8 12.2 0.4 16.1 5.2 44.7 45.3 0.6 0.0 20.7 7.3 1.4 0.0 0.9 0.8 12.5 6.6 21.9 10.7 0.5 1.5 0.8 1.1 27.9 2.6 43.7 0.6 0.4 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 THRB "ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2" ENSG00000151090 "Thyroid hormone receptor beta" P10828 3 24117153-24495756 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 199.2;Cone photoreceptor cells: 164.7;Excitatory neurons: 688.0;Inhibitory neurons: 631.3;Oligodendrocyte precursor cells: 329.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 7.7;basal ganglia: 15.1;cerebral cortex: 17.6;hippocampal formation: 18.5;white matter: 6.7" "Group enriched" "Detected in some" 5 "basophil: 7.2;naive B-cell: 2.2" "Group enriched" "Detected in many" 15 "B-cells: 2.2;granulocytes: 7.2" "Cell line enhanced" "Detected in many" "K-562: 45.6;RT4: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002008, CAB002009, HPA061035" Approved Supported "Nuclear bodies" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies" "CAB002008: , CAB002009: , HPA061035: AB_2684422" "unprognostic (1.82e-1)" "unprognostic (4.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.20e-6)" "unprognostic (3.37e-1)" "unprognostic (2.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-3)" "unprognostic (2.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.46e-8)" "unprognostic (1.32e-3)" "unprognostic (6.75e-2)" "unprognostic (2.73e-2)" "unprognostic (3.34e-2)" 11.1 4.9 7.7 1.7 15.1 1.0 10.0 0.0 17.6 2.8 0.0 11.7 2.5 7.0 1.8 6.4 3.8 2.2 7.7 18.5 2.0 12.1 20.1 5.0 1.5 0.0 0.0 2.3 9.0 7.3 15.7 4.4 0.0 7.5 8.4 20.1 6.2 7.7 23.6 6.8 3.9 7.0 0.0 5.7 8.3 0.7 1.4 3.6 4.4 27.0 1.4 8.9 4.2 6.7 10.3 3.1 0.6 0.1 17.4 8.8 6.7 0.5 2.1 1.5 3.2 6.7 9.7 0.1 2.5 6.8 1.1 15.4 10.8 3.9 1.0 0.0 6.4 0.0 2.5 8.9 0.5 0.0 0.0 16.0 7.3 0.2 1.2 3.5 0.0 0.0 45.6 0.0 1.5 0.6 0.0 0.0 6.5 0.6 3.4 0.0 0.0 0.0 10.0 32.7 1.7 0.6 16.5 8.9 0.2 4.6 9.7 0.0 0.9 3.9 3.0 0.0 1.9 0.1 0.5 0.0 2.7 0.1 0.3 7.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.2 7.7 15.1 0.0 17.6 18.5 2.0 0.0 0.0 0.0 0.0 1.4 6.7 3.0 3.2 11.4 199.2 3.3 9.9 29.5 13.2 1.8 17.9 24.5 18.7 11.6 8.6 14.1 23.9 164.7 12.4 0.0 39.9 1.9 2.4 2.3 3.4 0.5 6.0 25.2 3.8 688.0 12.5 23.2 13.7 16.3 5.7 0.0 0.3 7.5 37.7 1.7 0.0 631.3 8.1 10.2 11.3 11.7 2.4 0.6 4.6 1.8 97.4 0.2 11.7 0.0 329.2 32.4 10.3 17.5 2.2 0.1 40.1 4.8 8.1 10.3 21.8 6.6 12.0 7.5 0.3 0.7 5.1 23.9 5.5 1.0 0.4 9.8 81.3 THSD7B KIAA1679 ENSG00000144229 "Thrombospondin type 1 domain containing 7B" Q9C0I4 2 136765545-137677718 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;retina: 19.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 25.0;Horizontal cells: 90.9;Inhibitory neurons: 153.4;Rod photoreceptor cells: 32.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Daudi: 11.0;SCLC-21H: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051416, HPA056745" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA051416: AB_2681477, HPA056745: AB_2683224" "unprognostic (4.65e-3)" "unprognostic (2.25e-1)" "unprognostic (8.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.80e-3)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.20e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-6)" "unprognostic (2.42e-3)" "unprognostic (1.89e-1)" "unprognostic (4.31e-2)" "unprognostic (4.30e-2)" 1.9 0.0 0.8 0.0 1.2 0.0 0.7 0.6 1.2 0.2 0.1 0.1 0.0 0.2 4.1 0.3 0.9 0.2 0.5 1.2 2.3 0.9 0.1 0.1 0.0 8.2 3.3 0.0 0.0 0.3 0.6 0.2 8.9 0.7 0.0 19.7 0.4 0.2 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 1.6 0.8 0.7 0.1 0.0 0.2 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.4 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.6 1.2 1.2 2.3 8.2 3.3 8.9 0.6 1.6 1.6 1.1 0.0 0.0 2.6 0.0 0.1 0.7 0.0 13.6 1.6 0.1 0.9 0.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 1.9 0.0 3.7 0.5 0.2 0.8 0.0 0.0 9.5 0.0 0.0 0.2 0.0 1.4 0.0 1.7 1.8 0.0 0.0 90.9 153.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 8.4 0.0 1.8 0.0 1.5 7.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 32.2 6.6 0.3 3.3 0.5 0.5 1.4 0.0 0.0 0.0 0.4 0.0 0.1 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 941.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 475.9;Late spermatids: 491.0;Leydig cells: 353.6;Peritubular cells: 770.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Group enriched" "Detected in many" 4 "granulocytes: 13.6;monocytes: 5.0" "Cell line enhanced" "Detected in many" "ASC diff: 1327.4;ASC TERT1: 1618.4;BJ hTERT+: 960.2;fHDF/TERT166: 1070.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" NA NA 110000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" 461.0 185.1 171.5 92.3 140.8 20.1 290.6 110.6 122.1 576.3 117.9 280.5 71.0 525.4 116.8 176.0 272.7 397.9 244.8 128.6 157.0 120.7 62.8 231.7 77.7 157.4 161.5 941.0 79.1 64.0 103.6 218.1 156.2 196.2 107.6 43.5 107.2 267.5 56.6 245.2 149.5 381.6 141.5 172.0 140.9 150.4 178.0 80.0 155.6 119.8 38.7 261.2 331.0 168.1 170.0 84.0 93.0 178.8 1327.4 1618.4 50.2 585.0 960.2 280.1 221.1 30.8 288.6 0.2 200.8 1070.2 307.4 32.9 29.1 25.2 291.4 3.4 16.6 0.1 156.0 48.1 392.7 2.6 1.2 641.1 12.0 276.8 44.3 722.5 375.9 54.4 0.2 0.5 292.5 19.5 176.8 29.7 16.6 34.2 122.8 118.0 213.2 73.4 178.7 2.3 47.6 290.3 366.6 170.8 776.3 111.6 86.8 42.2 450.3 744.2 140.5 438.0 102.8 84.1 74.9 1.5 171.0 32.0 367.6 0.0 5.0 7.4 0.0 3.4 0.0 0.1 0.1 0.0 2.2 0.2 0.2 0.3 13.6 0.2 4.3 1.4 0.1 0.9 171.5 140.8 110.6 122.1 128.6 157.0 157.4 161.5 156.2 141.5 178.0 168.1 147.9 112.2 34.3 24.2 18.7 98.9 9.0 5.7 9.1 37.5 9.7 37.6 41.9 52.9 20.8 25.8 8.4 4.3 6.1 46.0 0.0 78.0 143.7 17.0 190.3 115.0 7.8 12.4 9.8 22.0 87.7 475.9 17.9 24.4 7.0 97.5 259.5 7.9 208.8 3.3 107.7 14.3 12.2 177.4 171.4 491.0 353.6 184.8 275.7 96.5 87.3 39.9 5.2 60.8 143.5 83.3 6.0 770.7 33.1 10.1 12.8 0.8 5.4 12.7 92.1 111.8 171.9 8.5 7.7 5.6 75.9 14.8 17.5 96.0 2.3 6.9 TMEM119 OBIF ENSG00000183160 "Transmembrane protein 119" Q4V9L6 12 108589851-108598320 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biomineralization, Differentiation, Osteogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 8.3;Fibroblasts: 30.5;Late spermatids: 9.3;Melanocytes: 8.8;Microglial cells: 15.0;Peritubular cells: 24.0;Smooth muscle cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC diff: 559.2;ASC TERT1: 152.6;BJ hTERT+: 168.0;fHDF/TERT166: 81.9;HSkMC: 238.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051870, HPA052650" Enhanced NA NA "Cluster 6: Non-specific - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA051870: AB_2681645, HPA052650: AB_2681901" "unprognostic (4.90e-2)" "unprognostic (2.66e-1)" "unprognostic (6.84e-2)" "unprognostic (5.97e-2)" "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (6.67e-2)" "unprognostic (8.40e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.61e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.06e-6)" "unprognostic (1.29e-2)" "unprognostic (8.76e-3)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" 29.6 8.0 7.6 16.2 8.9 3.0 27.1 8.5 9.2 61.0 5.3 12.6 15.1 18.9 14.1 6.9 11.9 35.8 9.4 7.7 9.3 6.0 0.9 37.6 47.8 17.2 12.1 1.4 7.5 5.6 6.1 6.6 14.9 12.7 15.1 0.9 6.8 26.0 1.6 13.9 23.1 11.2 13.4 11.4 10.5 5.9 16.4 5.1 21.7 1.7 27.2 32.2 18.4 21.9 0.1 0.3 1.3 0.7 559.2 152.6 0.8 11.8 168.0 0.4 3.0 0.2 0.6 0.3 0.4 81.9 0.3 0.2 0.1 0.2 0.1 0.5 0.0 0.3 0.6 1.0 7.2 0.3 1.2 238.4 0.3 7.0 0.1 0.7 0.1 0.2 0.5 0.5 0.5 0.7 0.3 1.6 0.1 0.0 0.9 0.6 0.9 0.8 0.1 0.7 0.2 39.5 0.0 0.3 0.3 4.5 0.2 1.8 1.2 13.1 0.4 11.2 0.5 2.6 3.1 0.6 6.8 0.5 0.1 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.4 0.2 0.1 0.4 0.3 0.3 1.4 0.2 0.4 0.2 0.1 0.1 7.6 8.9 8.5 9.2 7.7 9.3 17.2 12.1 14.9 13.4 16.4 21.9 1.3 0.0 0.0 0.0 0.2 3.8 0.1 0.0 0.6 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 8.3 0.2 5.8 1.3 0.0 0.0 0.0 0.0 0.2 30.5 0.0 0.2 0.0 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 1.9 4.4 9.3 4.1 1.1 8.8 15.0 1.6 0.0 0.0 0.0 0.0 0.1 1.1 24.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 9.7 0.1 0.1 0.0 3.7 0.3 0.7 0.5 0.0 0.1 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" 15.0 13.8 5.7 8.0 6.6 6.8 13.1 6.8 9.0 14.6 19.7 12.9 7.1 15.0 17.3 15.5 14.4 11.3 30.1 6.7 6.4 10.6 8.9 9.9 10.7 6.0 6.1 30.9 9.5 16.4 8.1 26.8 6.1 13.9 9.4 10.6 12.9 16.8 13.6 20.0 9.1 16.6 6.4 16.8 9.7 17.0 6.9 10.7 9.9 15.9 11.0 12.8 15.1 6.1 18.0 17.7 20.0 12.4 27.0 17.8 8.2 16.9 20.8 16.6 24.2 10.9 29.9 21.4 37.7 19.0 22.8 22.1 23.1 16.4 17.0 14.3 17.3 12.1 19.6 11.8 19.9 18.5 12.8 17.4 27.6 16.9 10.8 19.8 14.6 16.6 5.1 13.1 12.4 29.5 13.1 13.6 14.9 9.5 19.8 12.1 29.8 12.3 20.1 22.8 6.9 9.9 12.5 21.2 23.1 17.9 11.7 10.4 17.6 13.5 11.8 24.7 21.9 12.7 12.0 30.8 22.6 21.9 18.6 2.2 5.1 12.9 9.9 3.1 8.4 5.2 6.9 10.0 7.5 5.0 9.5 8.9 7.1 14.9 2.7 5.6 9.6 6.4 5.7 6.6 6.8 9.0 6.7 6.4 6.0 6.1 6.1 6.4 6.9 6.1 13.5 6.4 2.6 5.9 7.6 11.1 12.1 19.8 6.2 17.4 13.5 12.1 12.3 2.8 9.8 14.7 6.2 29.1 13.1 9.6 3.9 4.4 0.6 22.6 10.5 12.1 13.1 6.5 12.1 9.3 10.7 15.4 2.0 11.2 5.7 22.7 23.9 7.2 11.2 18.5 12.3 5.9 18.3 11.7 12.0 3.2 22.7 11.4 14.2 6.5 16.1 12.2 17.5 10.6 8.2 12.7 9.3 23.7 4.1 8.6 8.3 6.8 17.5 9.2 46.0 9.4 14.1 11.7 16.8 11.0 20.0 17.2 9.8 24.3 5.1 17.7 TMEM200B TTMB ENSG00000253304 "Transmembrane protein 200B" Q69YZ2 1 29119429-29123903 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 60.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 8.8;Fibroblasts: 6.1;Leydig cells: 12.8;Melanocytes: 8.8;Peritubular cells: 15.1;Sertoli cells: 6.6;Smooth muscle cells: 9.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.2;BJ hTERT+ SV40 Large T+: 26.7;BJ hTERT+ SV40 Large T+ RasG12V: 29.5;fHDF/TERT166: 29.0;HBF TERT88: 25.3" "Low region specificity" "Detected in all" HPA055254 Uncertain NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA055254: AB_2682760" "unprognostic (2.55e-1)" "unprognostic (2.12e-2)" "unprognostic (8.25e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-3)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (1.52e-2)" "unprognostic (6.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.24e-2)" "unprognostic (1.81e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-3)" 16.8 4.4 2.0 4.0 6.3 0.0 11.8 6.9 3.3 47.2 6.6 29.5 2.3 60.6 7.8 5.6 21.5 7.3 7.0 1.9 2.4 9.4 8.4 10.5 1.2 2.2 2.1 33.3 2.5 26.1 3.6 6.5 2.2 24.6 4.1 0.3 4.1 39.7 2.2 5.8 9.2 35.1 2.0 6.4 6.4 13.3 2.6 1.0 5.0 2.6 1.3 20.9 24.3 2.1 21.0 0.0 3.4 0.0 28.2 23.4 1.1 14.4 22.6 26.7 29.5 1.1 2.3 0.0 3.5 29.0 9.8 0.4 2.3 0.0 25.3 0.1 0.9 0.1 5.7 1.8 19.6 0.0 0.1 12.5 2.7 20.1 3.9 1.1 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.3 1.9 0.0 5.8 0.0 0.0 0.0 0.3 0.1 0.0 1.7 20.7 0.0 0.1 9.5 0.0 0.0 0.0 9.4 0.4 19.9 0.4 0.0 0.0 0.0 11.6 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.3 6.9 3.3 1.9 2.4 2.2 2.1 2.2 2.0 2.6 2.1 2.0 3.2 0.6 0.7 0.2 1.9 0.4 0.2 2.8 0.8 0.6 1.8 1.0 1.5 0.7 0.0 2.1 0.1 0.2 0.1 0.0 0.0 0.1 1.0 8.8 1.3 0.0 0.0 0.3 0.0 0.5 6.1 0.0 0.6 0.0 0.0 1.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 1.2 2.4 12.8 0.1 8.8 1.9 0.1 0.1 0.0 0.0 0.1 0.0 0.1 15.1 0.0 0.3 0.0 5.9 0.4 1.9 6.6 1.1 9.5 0.3 0.6 0.2 0.6 0.5 0.4 0.0 0.0 0.3 TMEM221 ENSG00000188051 "Transmembrane protein 221" A6NGB7 19 17435509-17448668 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 7.9;retina: 9.4" "Group enriched" "Detected in some" 7 "Cone photoreceptor cells: 14.6;Muller glia cells: 49.2;Rod photoreceptor cells: 24.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 4.6;PC-3: 6.8;REH: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041580, HPA062945" Supported Approved "Nuclear membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane" "HPA041580: AB_10795700, HPA062945: " "unprognostic (3.60e-2)" "unprognostic (7.86e-2)" "unprognostic (4.51e-4)" "unprognostic (2.09e-2)" "unprognostic (2.61e-2)" "unprognostic (9.14e-3)" "unprognostic (3.19e-1)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.20e-2)" "unprognostic (1.98e-1)" "unprognostic (9.47e-4)" "unprognostic (2.37e-2)" "unprognostic (6.67e-2)" "unprognostic (2.76e-1)" "unprognostic (2.42e-2)" "unprognostic (1.23e-1)" 0.6 4.2 3.6 0.2 3.6 0.1 1.2 3.2 4.4 0.8 2.7 0.7 0.1 0.6 0.7 0.5 2.7 0.2 0.6 3.7 3.2 0.6 0.4 0.3 0.2 3.6 3.1 7.9 2.2 5.4 1.7 0.1 3.1 1.3 0.0 9.4 0.8 1.0 0.2 0.4 0.4 0.1 3.4 0.4 0.4 0.5 3.8 0.5 0.7 0.1 0.1 0.4 1.0 3.4 0.5 1.5 0.6 4.6 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.9 0.0 0.4 0.2 1.3 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.2 1.0 0.3 6.8 3.9 0.1 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.2 4.4 3.7 3.2 3.6 3.1 3.1 3.4 3.8 3.4 0.5 0.0 0.5 1.0 0.1 0.0 0.1 0.0 0.0 1.3 0.3 0.3 0.3 1.5 0.0 0.0 14.6 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.2 0.2 0.0 0.0 2.0 0.0 0.0 2.2 0.0 0.2 0.0 0.2 3.3 0.0 3.7 1.7 3.9 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.1 49.2 0.0 0.0 0.2 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.5 0.4 0.2 0.5 0.0 0.1 0.0 0.0 0.2 0.1 0.1 TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.7;ovary: 19.6" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 32.6;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 10 "glioma: 21.3;melanoma: 8.0;renal cancer: 7.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cell line enhanced" "Detected in some" "Karpas-707: 25.3;NTERA-2: 9.5;RPMI-8226: 17.1;SK-MEL-30: 27.7;U-2 OS: 11.8;U-87 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "HPA048470: AB_2680406" "unprognostic (3.41e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" "unprognostic (8.55e-4)" "unprognostic (7.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.36e-1)" "unprognostic (1.49e-3)" "unprognostic (2.02e-1)" "unprognostic (1.32e-2)" "unprognostic (3.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.17e-2)" "unprognostic (2.55e-4)" 4.7 3.3 7.4 1.8 5.8 0.7 3.2 4.8 9.2 11.9 1.7 2.6 0.7 1.9 1.6 2.8 3.8 1.1 1.3 3.8 27.4 1.4 0.6 3.0 3.6 22.7 48.7 19.6 0.4 1.4 3.8 0.2 33.0 1.4 2.3 1.5 1.2 1.8 1.4 2.6 2.3 0.9 19.9 1.7 1.8 0.2 36.8 8.1 0.4 2.7 3.8 1.9 8.5 11.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.5 0.2 0.0 0.1 0.3 0.0 2.9 0.0 1.9 0.7 0.7 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 25.3 0.4 0.0 0.0 0.1 9.5 0.0 0.0 0.1 0.0 17.1 0.0 0.0 5.1 0.1 0.5 0.0 27.7 0.3 0.0 0.3 0.0 0.0 11.8 0.0 5.1 0.0 5.2 3.7 29.7 0.0 0.0 0.0 0.3 0.0 2.8 0.1 1.4 0.2 0.2 1.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 7.4 5.8 4.8 9.2 3.8 27.4 22.7 48.7 33.0 19.9 36.8 11.5 0.1 3.2 0.0 1.6 0.0 0.4 0.1 0.1 0.6 1.9 0.2 1.3 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.2 0.0 0.0 4.4 0.0 0.4 0.0 0.3 0.4 0.0 1.3 0.0 4.3 0.0 0.0 1.0 0.7 1.6 0.6 1.6 5.4 1.9 3.7 0.3 0.0 32.6 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.5 0.0 14.6 0.6 0.1 0.1 0.0 1.3 0.1 0.4 0.0 0.0 0.0 TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 110.7;Astrocytes: 85.5;Leydig cells: 74.3;Muller glia cells: 148.0;Peritubular cells: 92.9;Sertoli cells: 92.1;Skeletal myocytes: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 112.6;fHDF/TERT166: 348.1;RPTEC TERT1: 83.6;U-2197: 74.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane" "HPA046658: AB_2679742" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (5.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.67e-2)" "unprognostic (4.23e-2)" "unprognostic (1.36e-1)" "prognostic favorable (4.05e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-2)" "unprognostic (2.76e-1)" "unprognostic (9.94e-2)" 40.0 20.8 34.8 8.5 38.3 0.0 18.8 27.1 39.5 46.7 41.6 25.9 8.6 45.7 33.4 34.6 35.1 28.6 36.1 30.8 35.8 27.7 24.8 21.9 6.2 36.5 38.7 21.7 11.3 5.6 6.6 1.2 33.7 32.9 14.9 17.8 29.6 45.6 23.8 6.3 11.5 51.0 37.8 7.5 13.8 4.9 39.5 3.1 20.2 31.1 4.2 36.2 20.1 33.4 0.0 1.7 50.7 21.4 43.8 33.1 0.0 112.6 0.3 21.8 18.7 0.1 0.0 0.0 9.2 348.1 0.0 0.1 14.5 4.0 32.0 0.0 9.9 0.0 13.2 0.0 25.3 0.0 0.0 30.0 0.1 8.9 9.7 38.9 24.8 0.0 0.0 0.0 41.6 0.9 0.0 0.0 6.0 0.6 0.3 0.0 25.3 0.0 83.6 33.0 0.5 0.0 0.1 1.3 0.0 5.4 0.2 0.0 0.9 44.0 4.4 74.4 4.8 0.0 0.0 0.0 18.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 38.3 27.1 39.5 30.8 35.8 36.5 38.7 33.7 37.8 39.5 33.4 110.7 19.2 0.6 85.5 0.1 8.2 15.9 0.9 1.8 8.3 10.8 12.7 27.7 10.0 1.5 16.5 6.2 0.0 0.6 0.0 7.9 0.8 0.4 7.6 4.6 29.8 0.0 0.0 4.3 5.3 0.2 48.3 1.1 6.2 2.5 0.7 46.4 17.5 0.1 30.3 25.6 0.0 0.0 0.8 11.7 3.8 74.3 1.2 65.8 13.1 0.0 148.0 0.0 5.0 2.2 3.0 0.0 92.9 0.1 14.3 0.0 13.4 2.0 7.3 92.1 84.7 67.1 0.3 2.1 1.9 5.3 0.1 0.7 0.8 0.0 12.1 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.7;BJ hTERT+: 18.4;HDLM-2: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" 41.6 28.5 57.4 9.8 55.3 3.1 36.6 49.4 66.5 37.6 48.9 68.2 9.7 38.2 7.0 13.9 37.7 15.6 39.6 54.8 50.4 32.9 16.5 37.7 15.8 55.7 54.2 42.7 23.2 11.1 18.0 11.2 53.2 39.4 5.7 2.9 26.1 27.2 16.9 15.8 26.7 13.3 52.8 38.4 38.8 5.6 57.0 4.8 22.9 9.3 5.5 47.1 30.1 52.1 0.0 0.5 0.7 0.0 14.9 17.7 4.0 6.9 18.4 7.7 5.7 0.1 2.5 0.0 5.8 16.3 0.8 1.4 1.4 0.6 1.6 20.3 2.0 0.9 0.4 2.3 12.8 0.0 0.0 15.0 2.6 2.8 0.3 3.0 12.1 0.0 0.0 0.0 7.0 0.0 0.0 0.5 0.6 0.1 7.5 0.1 0.0 0.1 11.6 0.0 0.0 7.9 2.5 0.0 12.6 0.1 1.4 0.6 16.1 15.1 1.1 0.1 8.8 0.0 0.0 0.0 2.4 0.0 10.5 2.6 3.5 11.6 5.1 5.9 6.0 2.9 4.3 3.1 2.2 1.8 4.1 4.2 2.0 2.8 1.5 2.5 4.0 1.1 57.4 55.3 49.4 66.5 54.8 50.4 55.7 54.2 53.2 52.8 57.0 52.1 115.9 9.6 12.2 0.0 20.4 6.1 11.1 1.5 6.8 6.7 21.7 41.7 4.3 17.2 3.4 16.5 0.0 1.6 38.3 2.5 7.9 15.2 0.4 4.1 15.2 33.9 1.2 3.2 0.0 12.1 0.8 42.7 4.6 8.5 34.3 6.8 48.5 3.4 44.3 20.2 0.0 3.4 0.0 59.7 26.8 1.2 50.7 62.1 19.6 0.0 28.6 46.6 40.2 0.0 0.0 8.1 1.7 50.4 3.6 6.7 0.4 39.6 0.6 2.6 59.2 34.4 56.7 0.2 1.1 2.1 7.5 0.8 38.7 9.4 4.1 6.0 TNNT3 "AMCD2B, DA2B, DKFZp779M2348, FSSV" ENSG00000130595 "Troponin T3, fast skeletal type" P45378 11 1919703-1938706 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 43 "skeletal muscle: 13906.8;tongue: 4507.7" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 542.6" "Group enriched" "Detected in many" 9 "head and neck cancer: 28.8;urothelial cancer: 19.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "basophil: 5.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.3" "Cell line enriched" "Detected in some" 21 "HSkMC: 24.0" "Region enhanced" "Detected in some" "olfactory bulb: 5.1" "Low region specificity" "Detected in single" "CAB002451, HPA037810, HPA056909" Enhanced NA NA 470000 "Cluster 34: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "CAB002451: AB_564151, HPA037810: AB_10966217, HPA056909: AB_2683273" "unprognostic (1.01e-2)" "prognostic favorable (7.37e-4)" "unprognostic (2.17e-2)" "unprognostic (2.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.29e-2)" "unprognostic (4.53e-3)" "unprognostic (1.20e-1)" "unprognostic (5.88e-2)" "unprognostic (4.29e-3)" "unprognostic (3.53e-2)" "unprognostic (4.34e-1)" "unprognostic (1.42e-5)" "unprognostic (2.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-2)" "unprognostic (2.90e-2)" 31.2 2.4 0.2 1.4 0.4 1.5 20.0 0.1 0.4 16.3 0.1 5.8 0.2 6.6 2.8 62.5 14.4 1.9 185.3 0.2 0.1 0.8 1.4 3.7 1.4 0.1 0.1 1.7 2.2 0.3 2.5 41.3 0.1 20.7 0.5 0.0 216.0 3.1 13906.8 8.8 3.0 1.3 0.1 2.8 3.3 5.2 0.1 5.4 7.6 4507.7 2.0 20.3 12.0 0.2 0.0 0.0 0.0 0.0 0.5 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 33.1 0.0 1.9 0.0 0.8 2.9 3.9 5.9 2.2 0.0 0.4 0.3 17.8 0.0 10.1 0.0 0.0 24.5 1.5 0.0 0.0 0.1 0.3 2.4 0.3 33.9 0.0 0.0 0.1 0.0 6.7 42.0 0.0 0.1 0.0 3.0 0.0 0.0 2.7 0.0 0.0 0.0 6.1 0.0 2.3 2.5 110.9 2.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 94.8 0.3 0.2 0.0 0.0 42.5 0.0 0.0 542.6 11.2 0.1 0.6 2.9 3.4 18.3 2.0 0.7 0.0 17.1 TNXB "TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 274.8" "Cell type enhanced" "Detected in many" "Adipocytes: 54.7;Fibroblasts: 318.4;Granulosa cells: 94.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 12.4;ASC TERT1: 20.1;U-2197: 15.8;U-87 MG: 8.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 1500000000 "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" 68.0 274.8 2.0 0.9 3.1 3.4 40.0 4.4 1.8 45.1 3.5 35.9 3.0 66.7 3.2 18.1 37.4 4.7 73.8 0.7 0.8 13.0 17.6 51.1 0.8 1.5 1.1 67.0 3.7 0.4 6.8 3.8 1.5 15.6 1.7 0.3 19.5 1.0 14.2 27.4 29.0 3.1 2.2 30.7 18.8 11.4 3.0 0.7 27.7 7.2 0.4 34.5 35.2 0.4 0.1 0.3 0.3 0.2 12.4 20.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.4 1.2 0.0 0.1 0.0 0.0 0.1 1.3 1.1 0.2 0.6 0.0 2.8 0.0 0.3 0.2 0.2 0.5 0.0 0.5 0.0 0.5 0.7 0.4 0.0 0.2 0.0 0.1 0.3 0.0 3.5 0.3 0.1 0.2 0.0 0.1 0.1 0.2 1.3 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.4 15.8 0.0 0.4 0.4 0.2 8.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.1 4.4 1.8 0.7 0.8 1.5 1.1 1.5 2.2 3.0 0.4 54.7 3.2 2.4 2.6 0.5 32.9 0.2 0.3 0.6 1.3 1.3 1.8 2.5 4.3 0.2 0.0 0.0 0.5 1.0 0.0 0.0 0.2 3.0 1.3 39.7 38.8 0.0 25.0 7.1 0.0 2.6 318.4 6.1 1.1 0.0 94.8 12.8 0.9 0.7 0.0 4.2 0.1 0.0 0.6 39.1 2.8 27.1 4.7 32.0 17.8 0.0 1.2 0.0 1.0 1.2 0.0 0.1 4.5 2.5 0.5 0.0 0.3 0.9 0.6 0.0 21.7 20.8 4.1 2.1 1.6 26.6 1.0 4.8 5.6 0.2 0.4 TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Excitatory neurons: 45.2;Horizontal cells: 42.1;Inhibitory neurons: 32.6;Oligodendrocytes: 104.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.4;AN3-CA: 5.4;SCLC-21H: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Mitochondria, Cytosol" "HPA036575: AB_10673501, HPA036576: AB_2675200" "unprognostic (3.66e-2)" "unprognostic (3.70e-3)" "unprognostic (9.98e-3)" "unprognostic (7.82e-2)" "unprognostic (2.05e-2)" "unprognostic (3.20e-2)" "unprognostic (2.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.85e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-3)" "unprognostic (5.48e-2)" "prognostic favorable (5.40e-6)" "unprognostic (4.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.03e-2)" "unprognostic (3.31e-2)" 3.8 6.6 100.8 0.7 136.7 0.2 2.5 55.3 120.4 1.8 0.0 12.8 5.2 3.3 0.5 11.0 10.4 1.7 9.8 112.3 69.9 4.4 2.7 10.2 0.3 110.3 102.3 1.8 6.0 2.1 19.5 2.2 107.7 2.3 1.8 6.3 5.7 3.6 10.5 8.2 9.5 3.6 47.5 2.6 4.9 2.2 124.6 0.4 6.9 5.3 1.4 6.8 2.7 185.2 0.2 7.4 0.3 5.4 0.8 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.5 0.0 1.9 2.9 2.9 0.0 0.0 1.5 2.5 0.2 3.6 0.2 0.8 0.2 0.3 0.0 0.7 0.0 0.1 0.2 0.0 0.1 0.1 2.7 0.0 0.2 0.2 0.5 0.2 0.8 0.7 0.3 0.1 1.0 0.2 1.0 13.2 1.6 0.8 0.3 3.6 0.3 0.7 0.2 0.1 0.2 2.7 0.0 0.2 1.0 0.2 0.0 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 100.8 136.7 55.3 120.4 112.3 69.9 110.3 102.3 107.7 47.5 124.6 185.2 1.6 38.5 10.0 6.8 0.7 4.1 1.4 0.6 9.6 21.3 3.1 2.4 18.4 2.8 5.3 1.8 0.0 0.0 1.1 5.7 1.9 2.4 9.1 26.6 0.9 2.0 10.2 0.0 45.2 0.7 0.3 3.3 3.1 5.8 4.5 0.1 2.2 4.3 3.3 42.1 32.6 6.5 0.0 0.0 2.2 7.2 0.3 1.2 1.8 4.7 0.1 0.9 0.0 6.6 104.7 0.7 5.2 0.4 3.3 0.8 10.3 1.1 13.5 2.4 0.0 1.5 4.2 2.2 0.8 6.7 3.1 0.0 4.8 0.1 4.8 4.1 TPPP3 "CGI-38, p20, p25gamma" ENSG00000159713 "Tubulin polymerization promoting protein family member 3" Q9BW30 16 67389809-67393518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 858.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 962.0;Melanocytes: 501.6;Respiratory ciliated cells: 1825.2;Suprabasal keratinocytes: 495.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 61.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 65.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 59.9;OE19: 40.8;RH-30: 31.1;SCLC-21H: 47.8;SH-SY5Y: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047629, HPA061691" Enhanced Approved "Nucleoli fibrillar center" NA NA 43000 "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "HPA047629: AB_2680108, HPA061691: " "unprognostic (1.63e-1)" "unprognostic (6.62e-3)" "unprognostic (1.35e-1)" "unprognostic (7.28e-3)" "unprognostic (4.48e-3)" "unprognostic (1.59e-3)" "unprognostic (9.22e-2)" "unprognostic (3.23e-1)" "unprognostic (1.46e-2)" "unprognostic (2.93e-2)" "unprognostic (1.02e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.84e-4)" "unprognostic (3.51e-2)" "unprognostic (9.44e-2)" "unprognostic (9.46e-2)" "unprognostic (1.86e-3)" 44.3 27.1 199.2 8.0 200.1 1.0 81.0 186.0 225.7 50.3 168.7 96.4 23.7 29.3 9.7 99.3 858.4 21.9 81.4 188.1 222.0 60.7 4.4 148.0 4.4 258.7 291.6 8.6 23.9 13.6 40.7 78.5 231.2 18.9 14.1 9.6 39.5 13.3 72.2 170.5 38.0 21.4 223.6 17.7 43.6 15.4 228.3 4.7 18.4 55.8 9.1 32.8 36.4 296.2 0.4 59.9 0.6 0.4 0.4 9.4 0.2 1.7 0.4 0.4 0.9 3.9 12.0 0.0 0.9 0.8 0.2 11.3 9.2 0.0 0.1 0.0 3.5 0.0 1.5 1.7 0.1 0.0 0.0 2.4 0.3 3.6 0.0 1.8 0.6 0.0 0.1 0.0 5.4 0.3 0.0 0.2 1.9 40.8 0.0 0.0 31.1 0.2 0.0 0.0 47.8 20.7 0.0 0.1 2.4 1.5 0.0 0.0 0.0 0.0 0.6 0.7 0.0 0.1 0.0 0.0 2.9 0.0 0.9 0.0 25.4 12.4 0.0 37.6 0.2 0.0 0.0 0.0 33.1 0.1 0.0 0.0 5.8 0.0 65.8 0.3 0.0 9.4 199.2 200.1 186.0 225.7 188.1 222.0 258.7 291.6 231.2 223.6 228.3 296.2 14.7 16.0 129.8 17.0 0.2 303.9 8.8 92.5 5.7 3.8 5.9 5.0 4.1 30.0 160.4 18.4 4.2 8.3 0.2 28.4 5.9 166.8 60.1 962.0 30.9 31.6 177.9 0.0 0.5 1.8 4.3 141.9 7.1 14.7 25.4 1.0 5.0 0.1 2.9 0.0 0.7 65.1 132.2 3.8 82.5 23.7 29.2 13.7 501.6 1.0 10.7 68.7 1.0 1.0 30.0 8.4 39.7 3.4 0.0 5.6 29.8 0.9 1825.2 8.9 236.7 259.3 163.7 8.1 5.8 1.6 495.3 80.0 5.5 0.8 27.3 10.1 TRIL KIAA0644 ENSG00000255690 "TLR4 interactor with leucine rich repeats" Q7L0X0 7 28953358-28958330 "Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 68.0" "Cell type enriched" "Detected in many" 4 "Astrocytes: 72.1" "Cancer enhanced" "Detected in many" "glioma: 20.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 22.2;SH-SY5Y: 40.0;SK-BR-3: 35.7;T-47d: 15.8" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (1.26e-3)" "unprognostic (3.29e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (2.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (4.27e-3)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (2.07e-2)" 4.7 2.3 40.8 0.6 61.3 0.0 4.1 57.4 35.0 2.9 7.3 2.0 2.0 3.6 1.7 2.4 2.3 1.0 4.3 32.5 40.8 5.9 0.6 2.6 0.4 58.2 65.2 1.6 0.5 0.8 1.6 1.1 46.1 1.9 1.8 1.0 8.2 1.4 3.1 1.9 2.4 3.4 49.7 2.6 2.3 0.5 68.0 0.4 2.9 0.7 0.3 2.3 3.5 35.9 0.0 0.0 22.2 0.0 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 6.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.8 40.0 0.1 35.7 0.0 3.2 15.8 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.8 61.3 57.4 35.0 32.5 40.8 58.2 65.2 46.1 49.7 68.0 35.9 7.0 12.8 5.3 72.1 0.0 0.0 0.2 0.0 4.0 0.4 7.4 11.0 2.7 0.0 0.6 1.8 0.0 0.2 0.0 0.1 3.9 0.1 0.0 0.4 0.2 4.3 0.0 0.0 0.7 0.0 1.9 15.9 0.0 1.1 0.0 0.2 2.5 0.4 0.1 6.7 0.6 0.4 0.0 0.0 0.0 0.2 1.2 0.5 0.0 5.6 0.0 17.1 0.0 13.0 0.4 0.0 0.2 0.0 0.0 0.0 0.1 1.8 0.0 0.8 13.1 15.2 4.9 0.5 0.7 2.2 0.0 0.1 0.1 2.0 0.8 0.1 TSHZ2 "C20orf17, OVC10-2, TSH2, ZABC2, ZNF218" ENSG00000182463 "Teashirt zinc finger homeobox 2" Q9NRE2 20 52972358-53495330 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 395.6;Leydig cells: 468.2;Peritubular cells: 803.8;Theca cells: 396.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0;T-reg: 2.4" "Lineage enriched" "Detected in single" 4 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "AN3-CA: 26.7;ASC diff: 11.3;HeLa: 23.6;SiHa: 15.3;U-2197: 13.7" "Low region specificity" "Detected in all" HPA038123 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA038123: AB_10670657" "unprognostic (9.24e-3)" "unprognostic (1.58e-1)" "unprognostic (9.35e-2)" "unprognostic (1.13e-1)" "unprognostic (1.21e-4)" "unprognostic (3.30e-1)" "unprognostic (4.30e-1)" "unprognostic (1.28e-1)" "unprognostic (2.16e-1)" "unprognostic (3.23e-2)" "unprognostic (3.33e-1)" "unprognostic (3.14e-2)" "unprognostic (9.88e-8)" "unprognostic (6.26e-2)" "unprognostic (3.81e-2)" "unprognostic (3.37e-7)" "unprognostic (2.97e-3)" 21.5 14.8 3.4 4.5 4.7 0.2 10.6 2.9 4.3 9.0 0.0 7.3 2.3 6.8 16.5 8.2 8.7 12.4 3.7 5.7 8.9 3.3 12.6 2.9 3.9 5.9 8.2 18.4 3.5 5.4 2.7 1.3 5.5 5.4 2.0 1.7 12.9 13.6 1.6 5.9 2.8 8.8 10.3 5.1 6.1 4.8 8.1 2.0 5.3 2.6 3.4 7.6 5.7 7.5 0.0 0.0 1.8 26.7 11.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 6.8 0.0 0.1 0.0 0.1 0.0 5.2 1.4 0.0 23.6 0.0 0.3 0.0 0.6 4.1 3.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.7 4.4 15.3 0.1 0.0 0.7 0.0 0.0 0.0 0.1 2.6 13.7 0.0 0.1 0.3 0.0 2.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.1 0.0 0.4 3.0 0.2 0.6 0.1 0.0 0.1 2.4 0.5 3.4 4.7 2.9 4.3 5.7 8.9 5.9 8.2 5.5 10.3 8.1 7.5 171.4 0.0 0.6 32.7 7.0 45.4 19.9 43.8 37.0 6.7 24.4 161.5 2.8 54.3 41.6 36.8 2.1 1.3 1.3 0.1 0.0 52.2 11.1 32.7 144.4 125.7 6.6 0.0 188.2 9.8 0.5 93.3 3.1 68.9 1.3 395.6 11.7 92.1 1.2 0.0 58.1 1.9 18.3 1.3 16.6 20.3 468.2 2.8 12.4 104.9 1.9 39.0 1.0 23.6 4.9 6.8 2.7 803.8 16.0 27.5 0.8 0.4 19.9 1.9 39.5 10.9 48.2 2.6 1.8 43.9 40.5 0.8 24.2 396.9 2.6 8.2 TSKS "PPP1R161, TSSKS" ENSG00000126467 "Testis specific serine kinase substrate" Q9UJT2 19 49739753-49763306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "testis: 120.0" "Group enriched" "Detected in some" 46 "Early spermatids: 887.3;Late spermatids: 1022.9" "Group enriched" "Detected in some" 5 "head and neck cancer: 1.1;testis cancer: 2.2" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "NB-4: 11.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA045729 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA045729: AB_10963430" "unprognostic (3.56e-1)" "unprognostic (3.75e-3)" "unprognostic (8.33e-2)" "unprognostic (1.67e-1)" "unprognostic (1.92e-2)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-1)" "unprognostic (3.55e-1)" "unprognostic (1.54e-1)" "unprognostic (3.04e-2)" "unprognostic (2.44e-1)" "unprognostic (1.51e-8)" "unprognostic (7.89e-3)" "unprognostic (1.37e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-2)" 1.1 0.1 0.2 0.1 0.2 0.5 0.9 0.8 0.3 0.8 0.1 0.2 0.0 0.9 0.0 0.3 1.0 0.3 1.5 0.2 0.2 0.1 0.2 0.4 0.4 0.1 0.2 0.3 0.2 0.0 0.0 0.9 0.2 0.4 0.0 0.1 0.3 0.1 0.3 1.8 0.2 0.1 0.1 0.5 0.2 120.0 0.2 0.3 0.7 0.0 0.1 0.9 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 11.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.8 0.0 0.4 0.0 0.0 0.0 1.0 0.7 0.7 0.2 0.2 0.2 0.8 0.3 0.2 0.2 0.1 0.2 0.2 0.1 0.2 0.3 0.3 0.0 0.0 0.0 0.1 2.0 0.0 0.0 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 887.3 1.0 0.5 0.7 0.0 0.8 0.4 0.0 8.6 1.9 0.0 0.1 0.0 0.2 0.4 0.0 2.5 0.0 0.3 0.0 0.0 1.3 0.4 1022.9 9.6 1.5 0.0 1.0 0.2 1.2 1.0 0.5 0.5 0.0 0.0 7.5 0.1 0.0 0.0 0.0 0.0 0.0 13.1 0.1 0.3 20.5 8.4 0.7 1.4 6.7 0.5 0.2 0.0 0.1 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 69.8;Glandular and luminal cells: 124.9;Inhibitory neurons: 88.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" 6.2 4.0 4.6 3.5 4.6 5.1 6.9 10.1 6.0 9.3 0.6 5.8 4.1 6.9 14.6 3.7 4.1 5.2 3.7 4.9 4.3 5.0 7.4 4.4 4.5 3.9 4.0 10.3 6.4 7.0 3.8 5.8 4.3 26.7 5.9 9.1 4.0 13.0 2.0 4.6 4.8 4.3 4.0 10.2 6.3 7.1 4.1 5.9 4.0 4.0 3.9 3.4 3.8 6.7 8.3 0.8 8.9 5.0 6.5 4.7 7.0 2.7 3.6 4.5 8.7 3.0 6.6 13.5 8.9 2.2 2.8 7.7 10.3 3.7 6.9 5.7 13.5 6.2 6.2 2.8 4.7 7.4 2.9 8.8 3.4 5.8 4.2 4.0 5.1 5.8 8.0 20.4 3.9 4.0 9.3 5.1 9.9 5.5 4.9 18.4 16.9 12.4 5.7 8.4 29.0 10.0 13.2 13.5 3.9 7.5 8.6 5.4 2.7 6.0 3.0 6.9 4.6 5.6 8.0 13.5 1.7 7.7 3.5 1.3 3.0 1.2 1.3 2.4 1.3 0.5 1.3 0.9 2.6 0.3 0.6 0.6 1.7 0.6 2.9 1.0 2.4 1.0 4.6 4.6 10.1 6.0 4.9 4.3 3.9 4.0 4.3 4.0 4.1 6.7 9.1 9.6 6.4 23.2 6.1 6.6 6.0 2.5 9.6 42.3 26.6 19.0 10.1 8.6 5.0 7.3 8.4 2.3 15.1 8.8 1.9 5.2 4.0 69.8 9.6 7.4 18.5 21.8 61.0 3.9 1.6 7.2 13.3 124.9 2.5 13.9 15.4 14.1 3.3 10.1 88.8 17.9 0.0 18.8 8.6 4.2 27.7 13.0 1.8 24.4 5.9 7.3 7.2 45.8 51.5 1.3 8.5 52.3 11.3 19.0 5.9 2.8 4.4 44.8 0.0 11.1 11.2 12.0 9.5 8.1 8.4 1.1 7.7 5.7 10.9 4.5 UACA "FLJ10128, KIAA1561" ENSG00000137831 "Uveal autoantigen with coiled-coil domains and ankyrin repeats" Q9BZF9 15 70654554-70763558 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 142.0" "Cell type enhanced" "Detected in many" "Adipocytes: 293.0;Cardiomyocytes: 175.1;Endothelial cells: 177.4;Microglial cells: 184.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 244.5;BJ hTERT+: 148.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041412, HPA043503, HPA056006" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA041412: AB_10966708, HPA043503: AB_2678517, HPA056006: " "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (2.56e-2)" "unprognostic (1.54e-1)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (7.01e-5)" "unprognostic (4.95e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.14e-3)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (1.03e-4)" 37.7 17.9 10.5 7.8 13.1 1.0 33.0 11.0 12.9 25.1 24.2 14.6 22.2 22.1 21.5 28.9 21.6 32.2 28.0 9.4 11.8 30.8 17.3 30.7 8.0 13.3 12.8 31.2 12.7 12.5 11.5 28.6 13.0 21.6 15.4 11.9 25.3 18.4 142.0 19.4 22.3 16.0 12.1 30.0 15.9 16.1 14.2 4.6 35.6 106.0 6.7 13.2 25.4 14.7 42.7 34.8 15.2 20.2 29.9 127.9 0.1 244.5 148.4 62.7 53.8 58.5 61.5 29.2 65.6 61.4 18.4 48.1 34.4 19.4 78.3 0.1 15.3 16.4 27.9 12.3 38.8 0.4 6.0 60.8 10.7 37.1 28.1 103.3 67.7 6.9 4.1 0.1 78.7 14.0 0.1 2.6 12.7 19.3 18.0 0.0 109.6 0.2 30.3 14.4 4.0 7.6 46.5 7.1 48.9 30.3 13.4 4.9 130.5 3.6 24.8 20.6 39.1 2.3 8.8 0.2 31.4 4.4 27.4 0.1 0.9 0.0 0.0 1.7 0.0 0.5 0.0 0.0 0.8 1.2 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.3 10.5 13.1 11.0 12.9 9.4 11.8 13.3 12.8 13.0 12.1 14.2 14.7 293.0 6.4 6.4 31.6 5.4 11.3 14.6 13.7 10.2 6.3 22.2 33.3 175.1 18.6 19.2 49.7 4.2 1.0 2.1 66.5 3.9 49.0 21.0 75.3 46.3 177.4 9.1 3.0 0.9 48.7 1.9 81.6 33.6 53.0 15.2 34.9 47.5 18.8 9.6 25.2 0.7 33.1 6.1 24.3 8.6 15.2 125.2 15.8 30.2 184.6 9.5 49.4 2.1 6.0 62.0 78.8 35.7 141.1 0.8 21.8 45.3 5.0 61.9 4.2 52.6 53.5 96.2 46.4 35.2 16.4 13.1 1.0 2.9 62.7 24.2 10.9 UBTD2 "DC-UbP, MGC30022" ENSG00000168246 "Ubiquitin domain containing 2" Q8WUN7 5 172209646-172283764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 76.1;Late spermatids: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035891, HPA035892" Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA035891: AB_2674846, HPA035892: AB_10670670" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "prognostic favorable (5.92e-5)" "unprognostic (3.45e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "unprognostic (9.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (5.92e-2)" "unprognostic (5.12e-2)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-1)" 13.5 11.4 7.6 8.7 9.0 1.6 17.5 24.7 9.5 24.6 8.7 15.0 18.4 21.0 9.3 10.6 12.0 16.1 10.3 7.9 8.4 15.6 15.7 13.2 9.2 8.4 8.2 21.1 12.5 11.1 7.0 17.1 8.3 13.4 15.8 9.2 11.9 12.7 9.8 9.9 22.1 17.9 7.9 7.2 12.2 35.4 7.8 12.0 11.5 15.7 10.2 14.5 11.3 8.3 21.9 16.7 78.1 61.0 48.1 42.9 38.0 27.8 33.2 29.9 43.8 36.5 15.9 18.7 23.5 43.6 51.4 15.1 41.7 30.3 40.1 18.0 30.3 5.7 17.6 28.4 32.6 13.3 10.3 33.1 37.1 31.9 25.7 25.8 36.5 28.8 2.3 7.5 28.6 23.8 23.7 27.8 33.4 19.0 21.1 43.5 38.0 7.2 36.3 23.0 22.9 57.9 30.1 27.0 28.4 39.9 23.3 21.7 26.6 39.6 29.2 21.0 23.9 6.8 19.9 17.8 13.9 18.2 31.0 0.0 0.3 0.0 0.2 0.4 0.3 0.2 0.2 0.1 0.4 0.2 0.3 0.2 0.0 0.1 0.2 0.7 0.5 0.1 7.6 9.0 24.7 9.5 7.9 8.4 8.4 8.2 8.3 7.9 7.8 8.3 15.2 6.4 4.8 14.0 3.7 22.0 25.7 12.8 15.9 8.4 22.2 12.1 5.5 11.5 11.9 9.2 0.0 9.8 5.6 22.8 17.6 14.5 76.1 9.7 28.3 12.3 8.9 0.0 14.9 12.0 21.7 31.4 8.6 23.6 0.0 14.2 13.9 15.1 6.8 25.2 22.5 12.2 14.2 6.5 44.5 130.9 24.8 9.8 14.2 9.4 5.8 16.2 1.0 25.6 19.8 21.6 9.8 21.1 2.9 29.8 20.5 17.2 6.8 3.4 6.6 16.7 19.6 5.8 9.7 17.0 18.8 8.1 4.0 11.9 13.7 39.6 VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.9;Muller glia cells: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 186000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" 209.8 82.0 45.7 12.0 51.3 3.9 151.3 41.8 53.1 103.6 48.2 151.5 12.1 99.9 7.2 50.8 72.5 19.2 253.3 38.7 45.1 84.6 44.0 82.5 14.4 54.8 47.4 82.6 84.9 18.3 104.2 9.8 45.0 92.7 4.7 12.7 57.7 28.5 143.8 77.3 59.5 10.2 44.2 55.9 89.2 17.5 50.6 6.6 83.7 51.5 9.1 118.0 77.5 37.3 15.4 25.9 9.9 28.1 49.7 36.8 12.7 14.7 27.8 13.1 16.0 13.8 31.7 19.8 28.6 14.0 28.8 20.8 15.8 11.5 2.3 20.6 15.1 16.7 33.9 13.3 45.4 4.8 20.1 39.6 12.0 19.6 12.2 33.9 18.4 20.6 20.2 32.5 22.2 31.8 27.4 12.6 7.0 10.9 22.3 32.1 20.5 46.5 11.0 19.5 14.0 46.4 12.4 38.1 57.4 7.6 25.1 5.6 13.0 50.8 30.2 23.1 8.7 90.5 45.5 15.4 41.6 5.3 25.1 0.3 0.2 0.6 0.9 0.0 0.8 3.0 0.8 0.9 0.4 2.4 0.9 1.6 0.0 0.4 0.0 30.5 0.5 0.4 45.7 51.3 41.8 53.1 38.7 45.1 54.8 47.4 45.0 44.2 50.6 37.3 54.1 19.2 32.6 43.8 27.6 12.7 6.7 10.1 2.2 47.9 32.8 65.7 204.9 10.0 7.6 14.7 33.3 9.6 68.3 11.9 39.2 14.8 1.1 24.2 47.7 21.9 53.3 4.4 7.3 12.9 16.8 68.6 5.1 31.6 18.4 62.7 19.6 9.8 51.4 65.6 26.6 12.2 20.3 31.5 21.5 3.5 60.9 50.0 35.6 19.7 17.7 130.6 12.3 29.1 11.8 14.5 7.3 109.1 12.3 11.5 20.3 31.6 8.9 39.6 6.6 47.4 53.7 0.5 1.2 6.4 13.9 8.9 19.0 34.3 12.8 7.5 VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4879.0;Langerhans cells: 4893.1;Leydig cells: 5013.2;Muller glia cells: 8977.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 18287.8;fHDF/TERT166: 10084.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" 3467.6 423.1 349.3 610.6 369.5 1455.5 2362.8 289.1 527.4 1816.3 568.1 923.2 218.4 1226.5 400.0 451.5 1458.7 960.2 1364.3 337.5 404.6 473.6 192.8 1133.2 806.2 667.4 328.2 3690.8 370.0 224.8 574.5 1030.0 443.7 570.0 400.8 731.0 628.5 551.8 363.7 1126.8 674.7 1109.3 414.6 819.9 522.8 251.7 472.7 412.2 1391.1 555.8 744.7 983.5 1366.6 425.5 21.2 1119.0 1981.0 3180.7 6407.4 18287.8 3.0 5238.5 3458.9 3859.2 3421.5 8.5 70.4 2.9 273.2 10084.4 1804.7 8.4 283.8 147.0 3734.1 3567.5 387.2 563.2 523.5 0.3 1967.3 301.1 222.8 6746.8 6.5 5712.0 3213.4 9020.8 6366.3 372.4 889.3 1575.4 6939.5 4.5 736.6 911.2 632.4 1.4 1394.0 564.8 2745.9 95.7 3925.3 0.8 8.1 946.6 1.4 6.9 5447.5 1133.1 8.6 341.8 5459.0 3819.8 1644.5 3244.7 6311.5 1754.4 953.7 130.4 5775.4 28.9 3726.3 667.8 751.8 215.2 219.5 469.3 278.7 176.3 357.0 285.0 866.0 117.5 217.1 217.2 409.3 99.2 471.2 342.3 481.5 615.4 349.3 369.5 289.1 527.4 337.5 404.6 667.4 328.2 443.7 414.6 472.7 425.5 3211.7 157.0 349.4 53.5 605.8 725.8 21.6 361.2 58.1 74.2 108.8 539.1 109.5 94.4 157.3 108.5 50.1 22.1 1110.1 9.1 5.9 198.8 58.1 922.9 2314.1 2923.2 309.1 236.5 0.4 569.0 45.8 3443.0 101.4 693.7 2776.4 4879.0 2195.6 19.2 3541.4 33.7 0.3 1.8 16.2 2841.2 4893.1 131.6 5013.2 3177.8 3082.5 85.3 3893.1 8977.0 259.5 1.0 0.4 525.9 1.5 2336.6 2097.2 79.5 3.1 181.6 90.7 284.1 1420.0 3171.9 3714.2 55.1 27.5 39.4 473.0 52.7 1566.3 1791.1 6.2 28.9 VSTM5 "C11orf90, LOC387804" ENSG00000214376 "V-set and transmembrane domain containing 5" A8MXK1 11 93818232-93850618 "Predicted membrane proteins" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.7;placenta: 4.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 22.3;Excitatory neurons: 5.2;Inhibitory neurons: 9.2;Syncytiotrophoblasts: 5.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.2;OE19: 3.7;PC-3: 5.4;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029525, HPA063591" Uncertain Uncertain "Endoplasmic reticulum" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA029525: AB_10600789, HPA063591: AB_2732704" "unprognostic (1.26e-1)" "unprognostic (4.48e-3)" "unprognostic (2.78e-1)" "unprognostic (1.54e-4)" "unprognostic (2.45e-2)" "unprognostic (9.91e-2)" "unprognostic (8.56e-2)" "unprognostic (1.37e-2)" "unprognostic (1.68e-2)" "unprognostic (1.04e-1)" "unprognostic (2.52e-2)" "unprognostic (2.13e-1)" "unprognostic (1.31e-1)" "unprognostic (3.53e-2)" "unprognostic (2.37e-1)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" 0.2 0.2 2.2 0.1 1.9 0.0 0.4 1.0 3.4 1.1 0.1 1.1 0.1 0.4 1.2 0.1 0.2 0.4 0.1 1.8 3.7 0.8 0.0 0.1 0.0 3.1 2.0 0.1 0.5 0.1 0.6 4.4 3.3 0.5 1.7 0.5 0.4 0.4 0.0 0.1 0.7 0.7 1.4 0.0 1.9 0.2 3.3 0.0 0.1 0.0 0.1 0.2 0.1 2.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.5 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.0 0.0 0.1 0.0 0.1 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 1.0 3.4 1.8 3.7 3.1 2.0 3.3 1.4 3.3 2.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.9 0.5 0.5 0.3 0.0 0.1 0.0 0.0 22.3 0.1 1.1 0.0 0.4 0.0 0.3 0.2 0.1 0.0 0.0 5.2 3.0 0.7 0.3 1.5 0.7 0.0 0.1 0.0 0.0 1.5 0.0 9.2 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 1.1 2.1 0.4 0.0 0.1 0.5 1.5 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 5.9 0.0 0.0 1.6 0.1 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Alveolar cells type 2: 128.0;Astrocytes: 124.7;Excitatory neurons: 261.4;Inhibitory neurons: 240.9;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 296.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Cell Junctions" Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 6: Brain - Smell perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA044144: AB_10969458" "unprognostic (3.36e-1)" "unprognostic (3.22e-2)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-3)" "unprognostic (7.22e-2)" "unprognostic (6.48e-2)" "unprognostic (1.93e-1)" "unprognostic (4.87e-2)" "unprognostic (2.34e-3)" "unprognostic (6.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.25e-3)" "unprognostic (2.00e-1)" 4.7 3.5 11.3 2.5 11.7 8.2 3.2 17.7 15.7 2.5 6.5 1.6 1.8 3.9 4.0 2.0 4.2 2.8 4.9 10.4 6.9 3.6 2.4 2.5 3.3 6.4 5.4 4.6 1.5 2.9 1.9 2.6 8.4 2.6 1.8 12.2 2.2 2.1 5.3 3.4 1.7 3.0 3.2 3.3 3.3 5.1 6.3 3.6 3.5 2.9 2.7 1.8 1.1 18.6 5.2 4.6 3.3 4.0 3.7 4.6 3.0 4.3 2.2 2.8 2.3 3.3 2.6 5.8 3.5 2.9 3.3 3.4 2.3 2.8 3.3 5.7 3.8 6.1 3.5 2.8 2.5 5.0 4.1 2.3 1.9 2.9 1.9 3.7 2.9 6.7 2.3 5.7 2.9 5.3 5.8 5.1 3.9 2.7 1.7 6.2 4.3 5.0 1.9 2.5 5.2 5.2 3.7 4.4 5.3 4.7 3.8 3.9 4.7 4.6 7.2 4.0 3.6 5.3 3.6 10.3 5.2 5.3 5.3 6.6 2.8 1.5 1.9 1.5 3.7 1.8 1.7 2.6 2.3 3.1 2.3 3.6 1.9 3.8 1.3 2.7 1.5 1.1 11.3 11.7 17.7 15.7 10.4 6.9 6.4 5.4 8.4 3.2 6.3 18.6 6.0 169.9 128.0 124.7 8.0 4.1 3.2 4.3 2.8 16.1 4.4 3.2 10.1 7.2 59.6 1.8 22.9 2.5 5.5 0.8 1.9 2.6 46.7 17.9 6.2 14.4 0.0 7.8 261.4 2.2 2.6 13.5 6.6 3.7 65.0 7.4 5.0 1.8 4.0 11.8 240.9 1.3 4.1 3.0 4.4 17.5 4.4 8.4 5.4 103.0 3.8 7.5 6.2 136.2 296.3 1.8 1.6 3.8 5.1 1.5 0.5 4.5 98.8 27.4 0.0 8.6 5.7 16.1 9.5 2.3 3.4 1.9 9.4 4.0 1.1 1.7 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WLS "C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP" ENSG00000116729 "Wnt ligand secretion mediator" Q5T9L3 1 68098473-68233120 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 235.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 22.1;neutrophil: 61.7" "Group enriched" "Detected in many" 46 "granulocytes: 61.7;monocytes: 22.1" "Cell line enhanced" "Detected in many" "AF22: 392.1;ASC TERT1: 294.1;SuSa: 357.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069520 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Cytosol" "HPA069520: AB_2686144" "prognostic favorable (4.03e-4)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (8.13e-3)" "unprognostic (5.93e-2)" "unprognostic (4.51e-3)" "unprognostic (5.41e-3)" "unprognostic (7.46e-3)" "unprognostic (7.70e-2)" "prognostic favorable (9.43e-4)" "unprognostic (1.34e-1)" "unprognostic (4.82e-2)" "prognostic favorable (3.67e-7)" "unprognostic (4.48e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-2)" "prognostic unfavorable (3.51e-4)" 36.8 42.9 77.4 21.5 70.8 4.6 36.4 63.6 73.5 46.9 124.7 73.9 23.8 49.1 135.8 62.3 48.7 68.2 63.7 62.0 89.1 92.6 23.4 53.0 13.0 109.4 127.8 76.7 83.6 38.5 16.9 77.3 91.6 71.7 57.4 137.2 32.6 102.0 14.2 45.9 34.0 61.9 101.6 29.7 56.6 23.9 132.2 13.5 22.6 25.2 19.2 64.4 37.8 98.8 11.5 17.3 392.1 0.3 214.0 294.1 228.4 55.6 135.1 75.7 104.0 24.3 26.2 0.2 54.9 16.0 70.7 116.0 89.3 91.7 63.6 0.6 67.8 0.4 45.4 0.2 187.2 0.1 0.9 214.0 60.3 185.3 60.6 77.2 181.0 21.4 0.0 1.0 113.0 1.7 0.3 1.3 17.7 24.7 27.3 0.1 82.2 0.5 13.5 60.3 21.8 46.0 51.0 2.3 67.3 357.0 10.6 1.6 209.7 71.7 56.9 116.9 76.1 26.6 0.8 0.2 165.0 1.8 134.1 0.0 22.1 0.0 0.0 5.4 0.1 0.1 0.0 0.0 0.9 0.1 0.0 0.0 61.7 0.0 0.7 0.3 0.0 4.8 77.4 70.8 63.6 73.5 62.0 89.1 109.4 127.8 91.6 101.6 132.2 98.8 20.9 48.1 34.6 145.3 1.2 42.4 60.1 28.5 95.0 8.9 25.4 61.2 32.6 42.9 41.3 27.6 139.7 134.7 0.9 65.7 9.8 74.3 15.3 110.8 60.1 31.5 9.6 0.0 27.0 60.3 6.7 44.9 28.5 235.3 5.7 4.6 43.5 10.9 24.9 13.5 132.3 24.5 61.1 10.6 11.2 9.4 32.6 14.7 19.6 61.8 18.0 11.8 0.0 59.3 3.7 69.1 27.2 55.3 0.2 31.3 8.9 36.2 81.1 166.4 39.5 15.7 46.4 0.8 1.0 39.7 30.0 55.1 3.2 39.2 38.4 46.8 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 306.3;Inhibitory neurons: 1019.5;Oligodendrocyte precursor cells: 721.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "REH: 2.6;RPTEC TERT1: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (7.15e-4)" "unprognostic (1.28e-3)" "unprognostic (6.98e-2)" "unprognostic (5.63e-3)" "unprognostic (7.39e-2)" "unprognostic (5.68e-3)" "unprognostic (6.33e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-3)" "unprognostic (6.63e-2)" "unprognostic (3.46e-4)" "unprognostic (2.08e-2)" "unprognostic (2.39e-2)" "unprognostic (7.36e-2)" "unprognostic (4.96e-2)" 0.1 0.2 7.6 0.5 7.1 0.0 0.0 0.9 8.1 0.3 0.0 1.7 0.2 0.1 0.2 0.5 0.1 0.2 0.7 7.0 2.2 0.1 0.0 0.0 0.4 0.1 2.2 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.4 0.6 0.3 0.5 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.1 5.8 0.5 0.0 0.0 0.4 0.3 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.6 7.1 0.9 8.1 7.0 2.2 0.1 2.2 0.0 0.0 5.8 1.1 0.5 9.6 18.7 7.8 0.1 0.4 0.6 0.0 0.6 12.5 0.1 0.3 2.1 0.0 9.3 3.7 35.5 0.1 0.4 0.1 0.0 0.1 0.9 0.6 0.2 2.4 0.0 0.0 306.3 0.9 0.1 2.3 0.0 1.1 0.0 0.2 1.1 0.4 0.1 0.0 1019.5 0.0 0.0 0.0 1.0 0.0 0.0 1.4 8.8 30.0 1.8 0.6 0.0 721.3 9.4 0.4 0.0 0.0 0.4 0.6 0.0 0.1 5.2 1.6 0.0 2.6 0.4 1.1 0.1 0.2 0.9 0.1 0.5 0.1 0.0 0.7 XYLB "FLJ10343, FLJ12539" ENSG00000093217 Xylulokinase O75191 3 38346760-38421348 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Xylose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.3;Hepatocytes: 49.3;Inhibitory neurons: 35.9;Proximal tubular cells: 31.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037863, HPA038415" Uncertain Approved "Nuclear speckles" NA NA 12000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA037863: AB_10672729, HPA038415: AB_10672592" "unprognostic (2.48e-1)" "unprognostic (9.72e-2)" "unprognostic (3.42e-2)" "unprognostic (6.25e-2)" "unprognostic (7.52e-2)" "unprognostic (5.19e-2)" "unprognostic (5.82e-2)" "unprognostic (1.26e-3)" "unprognostic (6.55e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-3)" "unprognostic (4.63e-2)" "prognostic favorable (8.57e-4)" "unprognostic (3.26e-1)" "unprognostic (2.06e-1)" "unprognostic (5.78e-2)" "unprognostic (3.37e-2)" 1.4 2.3 1.3 1.5 1.0 2.2 3.0 5.4 2.0 1.6 0.0 4.1 5.8 1.9 0.8 1.9 1.1 1.6 0.5 0.9 0.7 11.4 33.4 0.7 1.0 0.9 0.2 2.2 2.5 1.1 0.8 0.9 1.1 1.6 4.6 2.1 5.3 0.9 0.6 1.5 6.4 1.4 0.0 1.0 3.5 1.0 0.9 1.6 0.7 0.5 0.8 1.2 1.3 0.6 3.5 6.4 2.8 6.7 4.2 4.3 6.3 5.9 2.0 4.5 4.4 8.2 3.6 3.7 1.4 7.6 5.4 2.5 8.1 2.5 5.6 5.0 6.2 7.5 5.0 24.1 2.2 10.1 7.7 3.0 5.2 5.8 2.7 1.9 4.7 8.5 18.0 6.2 5.0 2.4 8.3 1.4 3.8 8.9 7.9 4.2 5.5 5.0 0.6 6.3 3.6 3.2 3.7 16.0 12.7 2.4 7.2 6.1 2.6 9.0 7.3 15.6 2.5 3.5 6.6 8.5 5.4 9.1 7.2 1.4 0.9 2.0 0.6 1.6 0.5 0.2 0.5 0.3 1.7 0.3 0.6 0.6 1.9 0.5 1.4 0.6 1.5 0.4 1.3 1.0 5.4 2.0 0.9 0.7 0.9 0.2 1.1 0.0 0.9 0.6 1.0 0.0 1.3 14.0 0.9 0.9 2.1 1.8 6.8 3.2 3.0 3.4 1.1 2.8 1.5 0.0 0.0 4.3 1.7 3.8 1.9 1.0 0.5 0.4 3.5 1.8 0.0 3.4 39.3 3.0 3.8 2.3 8.6 1.0 0.0 1.3 1.1 49.3 4.0 0.0 35.9 5.7 2.0 1.0 3.7 1.0 1.5 2.0 0.0 17.8 1.0 0.4 0.0 17.1 17.7 1.3 5.8 1.9 1.6 1.7 13.0 31.7 1.3 5.1 0.0 2.4 1.4 0.5 2.7 4.1 0.9 1.4 0.8 1.8 5.1 2.1 ZDHHC11B ENSG00000206077 "Zinc finger DHHC-type containing 11B" P0C7U3 5 710355-784729 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 6 "brain: 29.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 23.0;Excitatory neurons: 47.2;Inhibitory neurons: 38.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 70.1;Respiratory ciliated cells: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.1;SCLC-21H: 2.4;THP-1: 3.4" "HPA057886, HPA069008" Uncertain Approved Mitochondria NA NA "Cluster 65: Brain - Ion transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA057886: AB_2683548, HPA069008: AB_2686068" "unprognostic (2.81e-1)" "unprognostic (8.38e-3)" "unprognostic (3.79e-2)" "unprognostic (5.11e-3)" "unprognostic (7.18e-2)" "unprognostic (4.02e-3)" "unprognostic (1.19e-1)" "prognostic favorable (3.98e-4)" "unprognostic (4.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.45e-4)" "unprognostic (6.94e-2)" "unprognostic (1.43e-2)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (2.31e-1)" 0.7 1.2 15.1 0.2 19.6 0.0 0.8 5.9 19.9 0.5 0.0 2.0 2.7 0.4 0.1 1.5 2.0 0.3 4.5 14.6 9.0 0.7 1.2 2.4 0.0 14.2 8.6 0.6 1.8 0.4 4.5 0.2 14.9 0.5 2.3 4.3 1.7 0.5 3.6 2.2 2.4 0.4 3.3 1.2 2.3 0.7 15.5 0.0 1.1 1.6 0.3 1.0 0.6 29.5 0.0 0.8 0.0 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 2.1 0.1 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.4 0.4 0.0 0.0 0.7 0.3 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 19.6 5.9 19.9 14.6 9.0 14.2 8.6 14.9 3.3 15.5 29.5 0.2 19.2 23.0 17.0 0.0 2.7 1.0 0.1 2.2 7.0 1.1 0.9 8.9 1.5 5.7 3.7 0.0 0.0 0.4 2.0 0.0 0.8 2.5 11.9 0.7 2.8 3.0 0.0 47.2 0.8 0.1 4.7 4.1 3.6 1.3 0.0 0.7 2.3 1.7 10.1 38.3 6.7 0.0 0.6 1.1 0.4 0.9 0.8 0.0 1.9 0.0 0.6 0.0 26.7 70.1 0.1 1.4 0.0 1.7 0.3 7.7 0.5 21.8 0.3 6.6 1.4 2.4 5.0 2.5 2.3 3.1 0.0 1.5 0.5 2.4 2.6 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.7;Horizontal cells: 122.8;Inhibitory neurons: 108.1;Oligodendrocyte precursor cells: 315.2;Oligodendrocytes: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 4 "HDLM-2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 2.9 1.6 7.3 1.8 7.6 2.5 1.6 9.7 6.8 5.3 1.1 2.4 2.8 12.4 0.4 1.7 2.0 2.3 5.2 7.5 5.1 4.6 4.4 3.0 2.4 12.5 9.1 1.4 2.5 5.6 1.6 2.2 10.9 3.5 1.7 1.3 2.1 1.4 2.3 1.4 4.1 6.1 13.5 3.1 3.8 3.3 10.8 0.9 1.7 3.9 2.4 2.4 1.9 22.7 2.6 2.7 0.8 3.8 2.0 1.5 8.7 4.1 3.7 2.8 2.5 3.3 1.9 6.4 1.4 3.3 5.4 1.3 2.2 2.2 2.5 50.9 3.2 12.7 1.0 1.5 2.7 1.7 2.8 1.1 2.3 2.9 1.2 2.4 4.3 2.8 10.4 4.7 1.6 1.7 1.1 4.2 1.6 5.1 3.2 0.2 0.4 3.9 5.8 1.1 6.3 1.9 4.8 3.1 3.5 1.6 0.4 2.0 6.0 4.2 3.1 8.3 5.2 1.1 1.3 0.9 1.5 4.5 4.7 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 7.3 7.6 9.7 6.8 7.5 5.1 12.5 9.1 10.9 13.5 10.8 22.7 23.4 3.2 0.0 45.4 9.8 12.9 2.1 3.0 4.0 25.3 5.8 8.0 18.3 12.8 1.4 7.3 6.2 12.5 11.2 7.4 11.7 7.5 10.7 5.0 16.6 15.1 2.4 4.2 161.7 3.1 2.2 11.4 6.1 9.4 0.0 7.7 22.5 23.1 11.4 122.8 108.1 9.8 6.1 15.5 6.7 5.9 8.1 8.8 10.6 65.6 3.8 5.4 7.2 315.2 221.0 2.7 8.5 10.1 4.5 14.2 6.0 3.8 0.4 6.0 0.0 6.2 8.4 7.2 10.0 1.5 8.4 21.1 6.6 4.6 11.5 2.7 ZNF25 "FLJ31890, KOX19, Zfp9" ENSG00000175395 "Zinc finger protein 25" P17030 10 37949573-37976647 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.7;Inhibitory neurons: 44.6;Late spermatids: 41.9;Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030190 Uncertain Approved "Nucleoplasm,Golgi apparatus" No No "Cluster 14: Monocytes - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA030190: AB_10602687" "unprognostic (9.42e-2)" "unprognostic (6.18e-2)" "unprognostic (5.64e-2)" "unprognostic (2.93e-1)" "unprognostic (4.67e-2)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (3.85e-3)" "unprognostic (1.15e-1)" "unprognostic (5.32e-2)" "unprognostic (1.40e-3)" "unprognostic (1.45e-1)" "unprognostic (2.01e-3)" "unprognostic (1.21e-2)" "unprognostic (1.29e-1)" "unprognostic (9.30e-3)" "unprognostic (2.61e-1)" 10.2 10.1 12.3 3.5 12.5 2.6 8.2 12.5 19.1 9.7 4.1 12.3 2.2 9.9 6.1 5.4 9.2 6.1 10.0 12.5 15.9 5.7 3.0 6.4 4.8 11.9 10.9 11.1 5.4 7.6 14.3 4.7 12.4 7.3 4.4 10.6 4.6 8.9 22.3 4.8 5.3 8.9 9.8 6.5 5.8 4.7 14.6 4.6 6.0 21.5 4.3 8.8 7.1 12.6 1.6 3.0 3.3 6.7 12.1 9.2 0.6 3.6 4.9 2.8 4.2 0.5 2.3 3.1 1.0 6.4 1.0 0.4 0.9 1.5 4.5 7.3 1.6 5.0 0.0 1.0 7.7 3.3 3.1 6.5 6.6 3.1 3.6 11.1 4.9 4.0 0.4 2.3 6.9 1.0 1.1 2.6 0.6 0.6 2.2 1.2 3.7 0.6 3.3 0.6 1.2 7.6 1.2 0.2 4.7 1.2 2.9 5.3 7.1 4.3 0.8 7.1 2.2 2.8 1.4 1.3 8.2 6.3 2.9 1.3 1.5 3.4 1.6 2.5 1.7 1.0 1.4 1.3 1.9 1.3 1.8 1.5 0.2 1.0 5.2 0.3 1.2 1.2 12.3 12.5 12.5 19.1 12.5 15.9 11.9 10.9 12.4 9.8 14.6 12.6 10.0 3.2 3.2 17.9 4.8 3.4 2.5 2.5 3.4 17.3 3.8 3.6 23.6 4.3 2.9 7.3 6.2 1.2 3.5 1.0 1.9 2.0 27.9 2.4 7.0 7.6 0.0 2.1 46.7 2.5 0.5 10.6 4.1 2.7 8.2 8.2 10.4 2.9 5.7 16.8 44.6 1.2 4.1 13.2 6.8 41.9 12.2 9.5 3.6 14.0 8.1 13.7 5.2 38.2 36.7 1.8 0.3 16.1 1.5 2.6 1.3 3.1 8.1 7.1 0.0 11.4 10.4 4.4 6.4 2.4 4.0 0.3 5.2 4.8 0.8 1.3 ZNF280D "FLJ20086, SUHW4, ZNF634" ENSG00000137871 "Zinc finger protein 280D" Q6N043 15 56630176-56734086 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 176.6;Oligodendrocyte precursor cells: 200.1;Oligodendrocytes: 293.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA030233 Approved Approved "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Golgi apparatus, Centrosome" "HPA030233: AB_10602590" "unprognostic (1.57e-1)" "unprognostic (2.17e-1)" "unprognostic (3.55e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.70e-2)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.15e-2)" "unprognostic (3.63e-1)" "unprognostic (7.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-2)" "unprognostic (1.98e-1)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "unprognostic (7.72e-2)" 11.3 11.4 3.4 8.7 3.9 23.1 15.4 9.0 4.6 18.0 4.8 10.2 7.5 20.1 8.1 8.4 12.4 9.6 9.2 3.6 3.8 10.3 13.2 10.1 10.0 3.1 3.0 23.7 13.7 11.1 4.5 11.5 3.6 10.6 11.5 12.4 10.5 9.9 12.6 6.6 9.5 15.1 4.0 10.3 10.3 7.8 3.5 35.9 11.5 11.6 9.9 10.9 8.5 9.8 13.4 7.4 13.6 20.9 13.3 18.7 9.9 20.2 14.3 8.2 9.3 5.4 13.6 22.7 8.4 14.5 7.9 10.0 6.7 5.3 9.9 11.6 4.1 2.4 12.5 8.2 13.3 20.4 6.6 12.8 7.6 5.6 8.0 20.6 18.3 23.0 11.9 25.7 13.0 9.6 14.4 2.3 0.0 15.6 5.8 4.3 22.2 16.1 10.1 15.4 11.2 20.0 16.9 10.5 6.7 0.7 11.4 19.9 16.2 12.1 18.2 11.3 16.1 13.2 21.6 0.0 13.7 31.0 13.2 7.8 2.6 3.5 2.1 2.2 2.0 3.4 1.9 1.7 3.6 3.2 2.0 2.4 0.4 1.8 2.0 3.6 1.9 1.0 3.4 3.9 9.0 4.6 3.6 3.8 3.1 3.0 3.6 4.0 3.5 9.8 32.4 9.6 18.9 176.6 31.1 11.1 18.3 12.9 42.7 79.8 20.5 20.7 37.9 22.8 14.6 3.7 83.4 23.0 25.5 12.2 7.9 12.0 18.3 14.3 33.0 36.5 32.3 27.5 107.2 14.0 21.5 37.5 26.0 14.2 17.7 37.8 34.2 31.1 36.6 69.0 151.3 25.7 16.2 35.6 18.1 49.5 33.2 22.9 16.0 91.8 27.0 24.9 28.8 200.1 293.3 10.5 10.4 21.1 41.4 21.1 26.8 14.2 12.8 84.5 6.6 47.4 30.8 49.4 33.8 26.8 13.9 13.3 21.4 27.7 22.2 16.3 ZNF423 "Ebfaz, hOAZ, JBTS19, KIAA0760, NPHP14, OAZ, Zfp104" ENSG00000102935 "Zinc finger protein 423" Q2M1K9 16 49487524-49857919 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;skeletal muscle: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 75.4;Late spermatids: 115.7;Microglial cells: 53.4;Oligodendrocyte precursor cells: 38.7;Peritubular cells: 54.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 62.6;NTERA-2: 33.2;REH: 27.5;SCLC-21H: 35.1;SH-SY5Y: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015258, HPA065820" Enhanced Nucleoplasm NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA015258: , HPA065820: AB_2685563" "unprognostic (2.81e-1)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (2.68e-1)" "unprognostic (2.86e-1)" "unprognostic (8.65e-3)" "unprognostic (3.37e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.77e-1)" "unprognostic (9.13e-2)" "unprognostic (8.97e-2)" "unprognostic (1.22e-1)" "unprognostic (6.64e-3)" "unprognostic (8.25e-2)" "unprognostic (2.92e-2)" "unprognostic (5.84e-2)" 9.1 2.9 13.5 2.3 9.6 0.3 6.7 14.0 10.2 6.3 1.0 4.3 1.3 5.4 3.4 4.7 9.3 5.8 7.8 9.7 11.0 2.0 0.7 2.9 1.9 14.9 30.4 7.6 3.4 3.0 4.0 4.2 11.8 6.0 2.7 3.6 2.8 9.5 27.5 2.0 2.6 6.5 8.6 1.4 2.0 4.5 26.3 1.8 4.3 14.7 1.2 3.9 5.4 7.8 0.0 0.0 62.6 3.3 5.1 0.6 7.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 1.4 0.0 0.0 1.9 0.5 0.0 3.6 0.1 0.2 0.0 0.0 4.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 8.8 0.4 33.2 0.0 0.0 27.5 0.1 0.0 0.0 1.7 35.1 87.7 0.0 0.1 0.0 17.6 0.0 0.0 0.0 0.0 1.0 16.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.5 9.6 14.0 10.2 9.7 11.0 14.9 30.4 11.8 8.6 26.3 7.8 12.7 0.0 0.0 75.4 0.0 2.7 0.3 0.1 1.2 9.8 0.6 0.6 2.6 0.0 0.0 0.0 0.0 0.5 0.1 2.3 1.9 0.2 23.5 2.7 7.6 11.4 0.0 0.0 10.9 0.2 0.7 15.8 0.0 0.6 0.0 1.6 15.4 0.9 0.7 0.0 7.4 1.0 0.0 0.3 5.1 115.7 27.7 0.4 1.8 53.4 0.0 11.7 0.0 38.7 5.1 0.2 0.4 54.5 0.2 0.1 0.2 0.6 0.0 1.1 0.0 4.5 6.4 0.8 1.9 0.1 1.7 0.3 0.3 5.5 0.7 0.1 ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 5.5;SCLC-21H: 6.6" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 72: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA028982: AB_10610705" "unprognostic (1.85e-2)" "unprognostic (4.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.90e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-5)" "unprognostic (1.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-4)" 0.9 0.5 0.3 0.3 0.3 0.3 0.9 1.3 1.0 2.4 0.0 2.4 0.1 1.9 0.3 1.7 1.5 0.4 0.8 0.3 0.2 0.3 0.4 0.5 0.6 0.2 0.2 2.0 0.6 0.2 0.8 0.2 0.3 1.2 0.5 0.4 0.8 0.4 0.4 0.9 1.0 0.7 0.2 0.9 0.7 0.8 0.2 0.6 0.9 0.3 0.4 1.6 1.7 0.4 0.6 0.0 2.3 2.2 0.0 0.5 0.9 0.4 0.3 1.7 1.6 0.7 0.6 1.2 0.8 0.2 0.5 0.6 2.3 0.3 2.5 1.0 1.4 2.7 1.3 0.4 0.0 5.5 0.8 0.1 0.6 1.2 0.3 0.3 0.2 1.9 0.9 1.8 0.7 0.3 3.7 0.8 0.9 1.2 0.7 3.3 2.9 1.6 0.3 0.4 6.6 1.2 1.2 0.1 0.8 1.8 0.4 0.8 0.2 2.7 2.5 1.1 0.9 0.3 0.6 1.3 0.7 1.8 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 1.3 1.0 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.4 4.6 6.4 9.5 17.6 7.6 2.0 2.4 2.5 11.4 15.0 2.8 3.8 4.9 1.5 1.3 0.0 2.1 3.2 3.3 0.6 1.9 2.5 1.1 0.6 11.2 3.2 1.2 8.0 83.3 2.0 4.2 7.6 3.1 1.1 3.8 18.2 2.9 0.7 1.7 3.3 64.3 1.9 4.1 3.1 1.9 1.8 6.5 2.3 1.8 23.4 1.6 5.9 6.2 30.2 15.9 1.0 0.4 9.1 6.0 1.2 0.3 0.7 2.0 7.4 0.0 8.4 4.2 10.7 12.2 18.3 1.3 0.8 6.4 3.6 2.4 1.4 ZNF704 "FLJ16218, Gig1" ENSG00000164684 "Zinc finger protein 704" Q6ZNC4 8 80628451-80874781 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 170.8;Oligodendrocyte precursor cells: 299.6;Oligodendrocytes: 342.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 72.8;RH-30: 46.0;SH-SY5Y: 58.4;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024285, HPA024302" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA024285: AB_2219847, HPA024302: AB_1859427" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.27e-1)" "unprognostic (3.39e-3)" "unprognostic (6.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (1.26e-1)" "prognostic favorable (4.02e-4)" "unprognostic (1.68e-2)" "unprognostic (1.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.90e-2)" 9.9 5.3 14.6 1.8 18.3 0.7 8.5 27.5 12.0 18.7 0.0 7.3 2.8 16.9 7.2 3.0 13.3 6.3 12.2 12.0 9.7 9.2 3.7 7.5 1.4 14.4 14.4 19.8 20.0 13.8 2.2 5.1 12.8 10.2 6.1 2.5 14.9 8.3 6.5 5.0 4.7 7.2 10.7 3.2 5.2 4.4 14.3 6.9 6.0 7.9 1.1 6.4 7.6 29.9 0.0 2.6 11.5 0.1 0.0 0.0 15.7 0.1 0.0 0.1 0.0 1.3 1.9 0.1 4.5 0.0 0.9 72.8 1.1 2.0 0.0 0.0 12.1 4.3 5.7 9.8 0.0 0.8 0.3 0.4 0.1 0.0 0.3 0.1 4.7 0.6 0.0 0.4 0.1 7.6 11.2 0.2 1.0 6.3 1.1 7.7 46.0 0.2 0.0 25.4 14.5 58.4 2.3 72.2 21.3 3.8 11.6 1.6 0.2 0.0 11.8 0.2 2.5 0.1 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.6 18.3 27.5 12.0 12.0 9.7 14.4 14.4 12.8 10.7 14.3 29.9 31.6 51.3 25.9 63.0 0.4 18.5 25.5 4.8 16.5 21.3 28.6 23.4 35.0 21.5 16.5 25.8 0.0 8.8 1.1 20.7 5.9 21.6 20.0 25.5 52.6 21.9 13.8 3.8 112.8 24.5 6.5 40.1 10.7 35.9 27.8 28.7 30.0 10.6 3.2 20.2 170.8 24.7 8.2 5.7 15.7 46.8 32.9 3.6 32.0 56.2 0.0 17.0 0.0 299.6 342.4 9.4 26.5 25.6 0.2 34.7 17.9 18.1 12.8 3.1 13.1 45.1 29.5 1.8 4.2 5.4 5.1 2.9 3.4 60.3 26.2 36.2