Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" 10.9 3.0 6.2 4.8 8.5 3.0 5.4 8.5 9.3 5.2 4.0 6.4 6.2 4.2 3.1 6.9 4.1 3.2 3.4 6.3 8.5 4.7 2.5 8.0 4.2 8.6 7.1 2.3 2.9 3.5 2.1 6.2 9.5 4.1 5.5 2.3 4.2 2.3 1.6 2.9 4.6 3.9 8.4 5.6 3.4 6.0 7.3 2.2 3.3 1.2 3.8 4.5 4.4 12.0 7.3 7.7 6.4 7.6 29.2 14.0 5.7 11.2 10.7 8.2 9.2 6.0 7.3 6.4 8.4 8.0 10.3 12.9 10.9 10.6 10.0 8.6 4.3 9.0 4.8 3.6 8.1 9.3 15.0 6.3 5.0 11.8 10.9 4.8 16.8 5.8 6.1 4.2 9.9 5.9 0.7 6.2 3.6 19.3 8.8 4.3 22.8 5.0 6.8 7.2 2.2 5.5 13.9 12.6 3.5 4.9 10.7 5.1 22.2 8.2 6.4 23.3 8.3 3.1 7.1 8.6 5.1 4.7 8.9 0.1 4.3 2.5 0.7 3.1 0.8 1.2 0.5 0.9 4.6 0.4 0.3 0.4 0.9 0.2 2.4 1.5 1.2 1.6 6.2 8.5 8.5 9.3 6.3 8.5 8.6 7.1 9.5 8.4 7.3 12.0 32.4 41.7 35.0 52.9 11.5 31.9 21.4 17.0 33.0 18.8 11.3 11.0 7.5 11.5 27.6 9.2 10.4 13.6 11.3 54.6 7.9 15.5 66.8 6.3 29.0 29.4 2.4 13.5 65.0 17.6 7.5 17.0 26.0 11.5 83.5 30.9 27.8 10.0 44.4 43.7 71.9 30.5 18.3 64.1 67.1 31.7 20.2 64.0 17.8 61.8 40.0 11.3 12.3 159.3 335.1 18.6 37.9 25.9 8.6 15.6 20.0 15.3 12.3 10.0 6.6 17.0 21.0 69.8 25.9 26.3 16.8 26.8 15.2 7.2 20.1 24.1 ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 47.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 1021.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.1;HSkMC: 11.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA035817, HPA035818" Approved Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA035817: AB_10671938, HPA035818: AB_2674801" "unprognostic (2.35e-1)" "unprognostic (9.39e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "unprognostic (3.29e-1)" "unprognostic (1.24e-1)" "unprognostic (7.31e-4)" "unprognostic (2.64e-1)" "unprognostic (9.16e-2)" "unprognostic (4.41e-2)" "unprognostic (8.03e-2)" "unprognostic (8.49e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-3)" "unprognostic (2.22e-1)" 1.6 0.9 1.7 0.7 2.1 0.4 1.1 2.6 4.5 1.4 2.0 0.9 1.1 1.1 0.8 1.0 2.0 0.9 1.2 2.2 2.0 2.4 2.7 1.1 0.8 2.1 3.5 1.6 0.6 1.2 1.3 1.0 2.2 1.2 0.8 0.8 0.6 1.9 0.7 0.4 0.8 1.6 1.8 0.4 1.2 47.5 2.5 0.8 1.5 0.7 0.9 1.7 0.7 2.6 4.0 2.5 0.2 1.1 18.1 5.5 0.0 4.7 3.0 3.1 2.6 0.0 5.2 0.0 6.5 5.9 2.0 2.5 1.5 2.5 3.3 2.9 1.7 9.3 1.9 0.5 3.0 1.1 0.9 11.8 0.6 3.8 0.7 2.0 5.8 0.9 0.0 0.0 5.7 2.0 0.2 0.1 4.5 3.5 5.3 0.6 0.0 0.1 3.3 1.0 3.1 2.1 5.9 1.4 0.1 0.6 2.5 4.1 2.4 0.0 0.0 2.5 0.0 0.4 0.2 0.2 1.1 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.7 2.1 2.6 4.5 2.2 2.0 2.1 3.5 2.2 1.8 2.5 2.6 0.9 0.0 1.5 0.3 0.1 0.4 1.3 1.6 1.2 1.6 0.4 0.4 0.7 0.0 2.0 0.0 2.1 1.7 0.1 0.2 1.9 2.3 1021.8 1.1 0.6 1.8 0.0 0.4 0.2 2.1 1.3 1.7 0.5 0.9 1.3 1.3 2.2 2.1 1.5 3.3 0.2 1.3 0.0 0.8 0.7 161.0 9.6 2.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.1 5.7 0.2 0.7 0.5 2.8 2.1 1.3 13.1 1.1 1.4 24.6 4.6 1.2 0.0 0.8 1.3 3.8 1.2 0.4 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 ANXA5 "ANX5, ENX2" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1156.8;Extravillous trophoblasts: 1125.1;Syncytiotrophoblasts: 1140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear membrane" "CAB003677: AB_425305, HPA035330: AB_2674574" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (9.70e-2)" "prognostic favorable (3.64e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.01e-5)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.33e-3)" "unprognostic (3.09e-1)" "unprognostic (6.04e-2)" "unprognostic (6.49e-3)" "unprognostic (4.54e-1)" "prognostic unfavorable (9.29e-7)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.26e-4)" 490.6 286.5 111.7 241.7 126.3 96.2 314.0 136.9 144.7 429.1 137.7 181.9 96.5 288.7 162.6 135.1 225.0 273.1 213.9 106.4 134.7 216.2 149.5 299.0 136.2 151.2 129.6 224.7 162.9 133.7 176.7 466.0 150.4 211.7 155.5 78.1 273.8 250.5 85.2 132.5 130.9 370.3 134.3 175.7 186.0 110.4 154.3 63.3 182.9 114.8 135.2 298.1 178.6 157.3 463.5 339.6 438.0 256.1 2094.3 1645.5 503.4 1582.7 1464.9 841.3 744.8 246.2 200.6 35.7 282.9 2224.8 581.7 165.4 287.3 727.6 762.2 335.1 171.2 105.0 281.6 647.4 1213.9 221.1 178.3 945.5 344.7 705.1 665.9 927.4 1120.9 25.2 106.0 271.8 2133.5 306.7 225.5 75.1 231.9 417.7 718.5 8.2 1014.5 72.6 1368.9 66.3 117.1 141.4 579.7 227.6 1515.2 872.3 201.5 261.2 830.6 1322.1 632.1 955.2 478.0 240.8 308.6 76.0 847.8 123.5 1586.2 122.2 725.8 359.9 104.8 830.5 136.0 127.3 158.8 131.9 745.6 89.5 51.3 74.6 157.9 48.4 798.0 91.2 289.9 773.3 111.7 126.3 136.9 144.7 106.4 134.7 151.2 129.6 150.4 134.3 154.3 157.3 286.5 243.6 233.9 13.7 85.0 199.3 266.4 395.9 76.2 6.8 101.6 107.4 88.3 265.9 257.2 132.4 25.0 1156.8 53.2 15.6 297.4 703.5 16.2 239.7 318.1 287.7 48.6 29.0 15.4 338.2 1125.1 564.7 91.3 312.6 148.7 177.5 186.4 54.8 753.2 13.5 7.1 110.9 187.2 446.5 705.1 41.4 379.9 544.0 352.2 45.0 412.5 161.4 13.4 23.1 26.8 501.1 31.2 366.3 203.1 473.8 15.3 194.3 268.9 30.0 295.9 443.1 377.2 15.9 28.6 101.1 140.8 1140.8 122.0 185.7 43.2 188.2 AP1M1 "AP47, CLAPM2" ENSG00000072958 "Adaptor related protein complex 1 subunit mu 1" Q9BXS5 19 16197854-16245906 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045256 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA045256: AB_10960697" "unprognostic (5.10e-2)" "unprognostic (3.71e-2)" "unprognostic (4.70e-3)" "unprognostic (2.85e-1)" "unprognostic (5.19e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.37e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (1.56e-1)" 49.5 47.2 30.1 30.7 31.0 58.5 37.9 22.3 36.3 32.2 22.0 37.7 32.1 38.8 9.2 29.6 29.8 21.4 39.9 33.0 31.0 39.6 81.0 31.9 36.9 26.6 30.0 31.7 18.8 20.1 24.0 27.5 33.5 25.3 12.6 17.3 21.6 24.8 44.4 30.8 31.0 35.4 23.1 37.6 27.3 60.8 25.0 37.8 23.7 29.0 28.2 38.3 29.1 25.9 63.3 70.2 69.3 65.3 82.7 80.9 39.1 69.6 74.1 99.5 103.3 83.9 48.6 49.8 78.7 76.6 64.4 35.1 54.2 56.9 111.3 85.5 122.3 80.9 63.4 114.6 67.1 91.5 96.9 83.5 42.2 89.2 59.8 65.4 95.6 69.8 40.3 98.0 109.5 75.8 131.2 55.4 56.9 22.3 162.7 87.9 56.7 67.3 54.9 45.2 44.4 99.4 56.8 34.4 64.0 36.9 41.0 73.1 83.1 111.8 45.6 151.7 134.3 104.6 141.6 54.9 125.5 112.8 88.7 89.4 142.3 243.9 104.8 180.7 105.6 99.8 103.4 111.2 121.6 92.3 115.1 147.0 101.8 133.1 235.7 131.2 161.8 174.3 30.1 31.0 22.3 36.3 33.0 31.0 26.6 30.0 33.5 23.1 25.0 25.9 17.4 41.7 31.2 12.7 30.6 4.6 7.4 13.2 11.4 35.4 11.3 10.9 17.9 14.3 15.2 12.9 20.9 32.1 30.5 8.3 15.6 21.1 32.5 10.6 27.2 22.7 19.8 21.7 11.8 18.2 40.4 28.1 8.6 14.8 27.1 19.0 21.8 41.9 42.6 42.1 11.7 7.3 6.1 36.0 13.3 92.1 23.0 30.2 10.6 5.6 34.9 18.3 38.1 4.5 12.8 31.2 5.9 19.9 24.5 6.2 25.1 23.6 13.9 40.2 0.0 26.1 22.8 61.9 23.3 12.6 7.1 17.5 32.9 17.7 9.0 4.6 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 BLOC1S1 "BLOS1, BORCS1, GCN5L1" ENSG00000135441 "Biogenesis of lysosomal organelles complex 1 subunit 1" P78537 12 55716037-55720087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 1180.5;Proximal tubular cells: 719.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA021381 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021381: AB_2228026" "unprognostic (1.27e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (1.59e-1)" "unprognostic (6.77e-2)" "unprognostic (2.22e-1)" "prognostic favorable (2.19e-4)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (1.83e-2)" 125.6 168.5 248.4 81.5 256.8 223.7 112.5 261.4 294.0 94.0 248.6 184.6 145.3 118.9 151.1 177.1 133.4 77.0 169.7 249.4 260.6 196.1 219.3 113.0 107.5 259.1 254.9 93.6 110.1 175.6 109.6 71.6 258.7 113.1 167.5 81.7 107.3 77.1 309.8 114.8 155.4 99.7 258.9 174.9 164.8 55.0 250.9 146.8 118.8 201.1 111.7 125.2 106.2 271.6 134.9 258.3 133.7 113.3 170.6 217.1 75.7 93.7 154.4 112.9 111.8 148.5 267.3 148.6 166.5 194.6 95.2 91.7 70.8 132.4 110.9 142.5 160.5 84.6 220.5 224.9 163.6 104.5 177.7 139.8 137.3 108.2 83.1 145.8 152.4 172.0 77.5 221.0 183.3 294.0 164.3 123.8 84.6 219.1 134.2 110.9 129.9 163.3 182.9 164.2 85.1 141.6 85.1 86.0 150.5 93.2 177.5 169.2 114.2 87.2 142.7 96.5 74.0 99.4 126.2 134.6 158.8 97.2 121.8 612.0 471.8 746.5 238.6 543.1 162.2 345.1 224.4 239.8 486.6 326.5 160.9 201.1 631.4 221.7 586.1 409.0 318.2 637.9 248.4 256.8 261.4 294.0 249.4 260.6 259.1 254.9 258.7 258.9 250.9 271.6 155.2 16.0 20.7 0.0 110.4 83.1 120.0 143.2 61.5 51.6 123.8 158.5 37.6 160.2 92.0 160.0 25.0 98.1 159.5 439.5 369.8 207.3 53.7 123.9 60.6 92.1 99.5 191.3 0.0 320.7 182.3 105.1 103.0 88.6 20.2 77.9 122.4 378.7 430.7 30.3 0.0 266.8 179.0 403.1 213.2 213.9 134.2 238.6 176.1 0.0 347.9 192.0 230.7 0.0 0.0 291.0 409.3 98.9 66.9 122.6 1180.5 719.6 114.2 92.9 78.9 133.9 208.5 46.9 55.0 86.6 88.9 73.2 111.5 77.4 256.7 180.7 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CDC42EP2 "BORG1, CEP2" ENSG00000149798 "CDC42 effector protein 2" O14613 11 65314866-65322417 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 50.5;Langerhans cells: 77.7;Pancreatic endocrine cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 50.4;intermediate monocyte: 118.8;neutrophil: 171.5;non-classical monocyte: 88.5" "Group enriched" "Detected in many" 15 "granulocytes: 171.5;monocytes: 118.8" "Cell line enhanced" "Detected in many" "HHSteC: 51.5;PC-3: 61.0;U-2197: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038562 Approved Supported Microtubules,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Microtubules, Cytosol" "HPA038562: AB_10671745" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (4.73e-3)" "prognostic unfavorable (2.89e-5)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.01e-1)" "unprognostic (5.36e-2)" "unprognostic (8.57e-3)" "unprognostic (3.81e-1)" "unprognostic (1.68e-1)" "unprognostic (2.66e-2)" "unprognostic (3.67e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-2)" 42.1 5.7 15.4 7.7 25.1 0.4 23.1 20.7 20.0 13.9 5.8 15.4 9.1 16.6 1.7 7.7 15.3 15.2 22.4 15.7 17.0 15.3 4.1 19.1 1.8 24.9 23.6 10.8 5.8 0.6 5.0 11.6 22.3 10.2 1.6 1.9 4.9 4.5 6.6 5.6 13.0 6.8 17.5 18.4 14.5 2.1 21.4 0.4 16.8 5.6 1.2 18.6 9.4 44.3 7.1 6.6 0.9 4.3 14.6 26.4 1.3 7.4 28.8 5.5 6.2 19.8 16.7 0.5 20.9 19.9 2.0 8.9 2.5 26.0 1.2 1.0 3.8 1.3 12.8 14.8 51.5 0.4 0.5 11.5 2.7 20.3 28.8 4.5 22.4 1.0 2.6 4.3 7.1 10.7 0.8 1.6 3.7 18.5 61.0 0.8 0.7 0.5 19.5 4.9 0.5 1.7 18.0 14.7 1.1 0.7 2.5 0.4 30.6 6.7 5.6 55.9 3.1 0.1 1.7 0.6 11.2 0.3 2.7 0.0 50.4 2.1 0.1 118.8 0.1 1.2 0.0 0.1 9.9 0.0 0.1 0.0 171.5 0.0 88.5 0.4 0.0 17.8 15.4 25.1 20.7 20.0 15.7 17.0 24.9 23.6 22.3 17.5 21.4 44.3 25.8 0.0 0.0 0.0 1.5 12.7 11.0 25.8 6.8 15.3 12.1 6.3 6.3 2.8 17.0 12.9 0.0 0.5 1.6 10.0 3.9 50.5 0.5 6.0 11.6 36.4 1.8 2.7 0.6 40.3 3.5 32.3 9.7 11.1 5.7 1.5 26.7 0.9 1.3 3.3 0.4 8.0 8.2 18.7 77.7 1.9 18.6 33.3 12.4 1.0 18.3 1.0 0.0 0.0 10.6 65.1 15.6 13.5 1.8 7.4 21.2 3.7 6.3 5.3 39.5 16.6 16.2 1.7 3.4 4.8 10.1 1.6 1.4 1.8 8.4 36.4 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F8A1 "DXS522E, F8A" ENSG00000277203 "Coagulation factor VIII associated 1" P23610 X 154886349-154888061 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.72e-2)" "prognostic favorable (1.67e-6)" "unprognostic (2.92e-2)" "unprognostic (2.57e-1)" "unprognostic (6.88e-2)" "unprognostic (6.61e-2)" "unprognostic (4.18e-3)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (9.23e-3)" "unprognostic (1.20e-1)" "unprognostic (1.80e-1)" "unprognostic (3.68e-2)" "unprognostic (6.28e-2)" "unprognostic (6.16e-2)" "unprognostic (5.61e-2)" "unprognostic (2.69e-1)" 23.1 23.7 30.6 12.9 30.1 33.1 21.0 25.4 39.5 13.8 22.4 19.6 15.2 18.8 22.7 17.6 13.3 7.4 25.5 31.7 29.8 22.8 44.6 17.1 19.3 30.8 28.2 8.8 22.2 14.0 13.7 13.0 31.9 16.3 14.9 14.8 21.8 18.1 27.6 16.5 20.1 14.8 26.2 23.1 15.6 5.8 31.3 20.6 19.6 18.1 20.0 19.4 13.3 32.2 106.4 47.2 9.1 14.7 31.3 14.8 0.2 27.5 22.9 27.8 36.0 18.6 40.2 11.4 87.9 16.7 36.3 11.0 13.3 12.7 22.8 63.3 6.3 11.6 13.3 18.8 9.5 21.1 5.6 28.6 11.6 9.2 5.2 20.6 6.0 29.1 1.2 41.8 16.2 53.8 34.0 94.9 16.3 0.0 54.7 64.1 9.0 10.0 31.8 35.9 45.7 19.0 16.7 20.1 36.4 0.0 23.7 41.6 17.1 15.7 36.0 11.6 22.1 41.6 43.9 101.4 8.3 76.7 36.0 0.0 3.0 6.8 2.9 3.1 1.6 1.5 3.2 3.5 3.5 2.5 3.6 4.0 6.0 0.8 1.2 4.2 1.6 1.7 30.6 30.1 25.4 39.5 31.7 29.8 30.8 28.2 31.9 26.2 31.3 32.2 5.5 12.8 2.6 5.5 14.4 6.6 5.2 1.8 2.2 12.1 14.4 12.4 13.6 27.1 1.5 40.5 6.2 4.0 19.5 11.9 49.0 2.7 0.3 9.2 11.9 7.1 6.7 9.5 7.2 2.0 6.2 7.4 6.6 9.7 5.7 7.6 7.5 24.6 11.2 3.3 6.1 10.2 4.1 27.3 16.8 1.5 10.8 16.9 10.6 7.5 16.7 7.3 30.9 6.6 9.6 2.5 5.7 12.4 4.7 3.1 10.4 57.9 2.7 7.0 6.6 4.6 6.1 0.4 1.5 7.6 6.5 1.6 19.0 8.9 9.8 2.8 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.6;Extravillous trophoblasts: 138.4;Rod photoreceptor cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.7" "Group enriched" "Detected in many" 4 "B-cells: 8.7;granulocytes: 5.7;T-cells: 2.1" "Cell line enhanced" "Detected in all" "ASC diff: 283.2;HHSteC: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" 105.0 72.3 37.1 23.4 37.3 5.1 72.5 29.6 50.7 31.2 55.3 27.5 4.8 27.9 31.7 9.5 26.7 12.1 88.9 36.9 35.2 29.4 23.7 45.4 21.6 34.8 33.7 35.7 25.4 11.4 14.1 64.0 38.9 21.3 4.6 15.0 14.3 13.1 45.2 13.4 28.1 19.4 29.8 22.3 22.7 13.4 37.3 4.3 18.1 14.8 20.9 36.7 21.4 35.3 37.3 11.4 3.6 22.5 283.2 57.0 71.5 73.1 177.9 77.0 73.7 16.2 13.3 27.5 46.5 147.1 60.0 20.1 13.7 199.4 40.8 7.9 7.6 22.7 48.9 32.8 243.6 2.1 4.5 62.5 85.2 92.4 175.4 46.8 90.1 14.3 22.2 50.8 132.6 42.7 8.3 11.3 10.7 4.1 29.4 46.4 142.8 76.8 86.0 13.0 5.7 7.2 83.4 11.2 77.9 29.9 16.4 5.0 61.2 74.5 51.1 22.0 32.6 15.5 8.0 35.0 62.4 11.2 55.2 0.0 0.7 5.7 1.6 1.2 1.4 7.7 1.4 2.1 0.6 8.7 0.1 0.5 0.3 0.6 0.8 0.0 0.4 0.6 37.1 37.3 29.6 50.7 36.9 35.2 34.8 33.7 38.9 29.8 37.3 35.3 164.6 32.1 5.2 54.5 39.0 6.8 8.2 15.6 2.8 11.2 23.3 26.2 19.5 18.6 2.0 5.5 8.4 38.9 15.2 35.7 1.9 46.4 17.4 8.2 31.2 57.7 6.7 13.0 31.6 20.6 138.4 31.3 16.8 13.1 7.0 12.4 20.3 9.8 19.7 1.7 10.0 21.0 0.0 3.9 43.0 14.0 28.6 16.5 35.6 8.4 8.0 48.5 5.2 17.1 17.6 16.4 6.7 17.7 13.1 10.7 6.3 13.9 2.9 120.3 19.7 97.3 90.2 2.0 5.5 3.5 5.5 68.0 17.6 16.1 15.8 4.3 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 305.6;salivary gland: 220.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 117.5;Hepatocytes: 131.8;Pancreatic endocrine cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 130000 "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 54.5 24.4 12.8 36.4 10.5 73.8 42.4 10.6 14.5 26.4 11.7 32.8 27.6 32.3 9.8 33.7 30.4 19.4 58.5 14.9 9.0 56.8 305.6 63.2 13.0 12.5 10.8 22.4 108.6 27.3 45.9 40.6 11.3 60.1 12.1 12.9 220.5 17.7 61.3 62.7 35.5 14.3 10.4 51.4 34.0 8.6 15.6 11.8 56.1 25.3 11.2 30.2 33.3 9.3 50.8 31.2 6.8 29.8 49.4 32.1 77.5 64.4 48.1 26.3 18.1 45.4 54.3 1.9 148.8 47.5 46.1 91.5 14.0 32.5 5.4 148.0 35.2 90.9 52.8 57.7 26.2 13.0 141.2 35.6 35.3 29.5 13.2 62.4 84.7 14.6 70.5 8.5 17.8 32.3 5.0 29.2 21.5 44.2 9.3 7.9 26.6 10.9 35.2 39.1 13.1 9.2 54.5 28.5 42.5 31.9 10.7 31.4 125.9 29.4 60.1 43.7 95.5 15.2 93.4 3.4 55.8 40.1 60.7 2.0 0.9 1.5 0.7 0.1 0.2 0.4 0.2 0.3 0.6 0.1 0.0 0.1 0.7 0.4 0.0 0.3 0.0 1.1 12.8 10.5 10.6 14.5 14.9 9.0 12.5 10.8 11.3 10.4 15.6 9.3 44.1 3.2 27.4 4.2 7.3 19.4 10.0 10.4 2.8 12.8 12.0 9.0 16.3 21.5 8.5 22.0 25.0 20.9 26.9 49.5 0.0 47.1 0.5 15.2 9.7 29.4 37.8 26.5 7.9 117.5 16.5 11.4 21.9 32.3 15.8 7.0 23.9 131.8 24.8 8.4 7.5 31.7 10.2 35.3 42.1 1.4 11.1 33.6 16.0 5.6 14.0 13.6 24.7 2.0 4.4 108.3 26.4 10.9 7.2 24.3 28.7 7.8 2.0 28.0 26.3 10.5 18.6 2.8 3.6 8.5 23.0 84.3 19.6 4.7 17.9 16.4 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 429.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 13000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavorable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 32.9 49.6 17.0 34.8 19.9 13.9 21.9 15.2 16.7 24.7 22.0 28.9 19.5 27.1 6.9 21.0 22.4 21.2 27.4 15.8 18.6 18.5 100.1 27.1 14.0 23.0 19.5 39.2 68.1 9.9 13.6 27.6 18.3 21.4 12.4 19.8 22.1 14.3 67.4 14.7 23.6 25.0 15.3 17.4 33.1 19.7 25.1 42.8 19.0 27.4 11.2 33.4 19.5 15.5 79.5 103.7 59.9 71.4 112.4 95.3 122.8 146.3 90.0 58.4 55.6 45.2 146.5 20.0 106.2 77.7 135.9 150.7 39.9 123.0 48.6 200.1 52.0 60.7 217.2 50.9 60.9 23.4 114.8 136.9 59.8 78.0 30.9 127.3 69.2 110.1 77.0 29.6 65.6 21.8 122.3 23.9 82.1 52.8 97.7 134.3 85.5 61.7 57.4 92.9 18.9 70.1 148.4 7.9 91.0 31.7 46.5 43.5 165.3 56.7 107.9 129.5 118.0 97.9 60.3 44.4 146.1 46.3 429.7 1.5 10.7 3.6 4.4 9.3 3.2 3.4 2.6 4.5 7.8 5.8 2.5 5.0 3.2 2.8 10.2 13.2 3.3 7.7 17.0 19.9 15.2 16.7 15.8 18.6 23.0 19.5 18.3 15.3 25.1 15.5 18.6 16.0 21.3 71.5 32.1 15.3 20.0 52.8 20.5 30.8 13.8 10.7 13.6 18.6 30.1 23.9 33.3 7.3 21.7 24.1 5.9 49.7 47.2 18.7 15.4 17.9 16.8 27.6 67.3 133.0 123.4 36.1 21.4 24.5 13.3 20.5 19.6 98.8 24.9 28.6 82.0 18.9 4.1 42.4 9.7 24.6 35.8 28.9 24.9 106.8 44.0 10.9 18.6 72.9 44.6 88.5 21.6 29.3 109.0 23.5 17.9 19.2 23.5 73.5 13.1 33.1 25.4 3.4 14.0 16.6 8.0 16.6 21.2 32.8 17.6 29.9 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 GTF3A "AP2, TFIIIA" ENSG00000122034 "General transcription factor IIIA" Q92664 13 27424619-27435823 "Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007990 Supported Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 52: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA007990: AB_1857960" "unprognostic (9.88e-3)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (8.64e-2)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (1.98e-1)" "unprognostic (1.33e-1)" "unprognostic (3.26e-1)" "unprognostic (1.41e-1)" 63.5 40.3 51.0 50.3 53.0 85.3 59.3 53.1 63.0 31.9 50.4 41.8 30.3 26.6 57.4 38.3 32.8 33.4 126.7 52.8 51.9 52.5 129.8 33.2 81.2 53.2 53.3 16.0 116.4 34.5 26.9 28.4 52.7 30.7 40.4 10.4 70.4 34.8 89.3 25.0 32.3 38.0 53.0 54.6 46.9 17.4 52.9 111.6 31.2 132.6 89.8 46.0 23.7 56.2 91.2 78.8 65.4 136.8 90.4 98.8 93.3 95.1 86.0 118.3 75.4 118.5 139.4 275.3 65.9 112.6 73.9 64.9 136.6 131.0 165.8 289.2 93.1 229.9 71.6 135.4 102.5 432.3 150.9 81.5 137.9 109.2 142.4 81.8 107.2 246.9 184.2 88.6 140.5 178.3 311.3 467.9 115.8 299.6 210.7 154.8 169.3 254.0 142.5 39.2 158.9 81.5 67.6 101.6 141.7 83.7 73.7 223.6 66.0 62.5 67.1 49.3 99.1 57.0 104.9 275.1 67.1 264.9 117.4 116.8 173.8 162.5 250.2 180.1 335.2 290.5 251.6 271.7 218.4 250.3 192.5 219.6 38.3 243.7 169.5 298.3 345.1 484.4 51.0 53.0 53.1 63.0 52.8 51.9 53.2 53.3 52.7 53.0 52.9 56.2 96.9 44.8 33.0 15.0 183.3 63.2 62.4 109.1 56.3 41.7 107.2 117.6 207.8 91.5 58.3 27.6 29.2 76.3 207.1 20.0 150.6 195.7 33.9 60.1 68.1 76.3 34.8 126.4 28.7 190.6 187.4 75.0 63.2 49.1 75.5 93.0 40.0 146.7 215.5 35.3 25.8 60.6 77.3 156.1 119.3 85.6 63.6 133.9 97.8 15.9 185.3 73.1 236.9 7.1 24.3 153.3 28.9 58.3 248.4 122.7 35.6 207.7 37.9 35.7 85.5 58.3 76.1 34.8 145.1 83.4 64.4 42.1 187.1 89.0 69.8 70.3 H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774383-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 565.0" "Cell type enhanced" "Detected in some" "Adipocytes: 58.1;Cytotrophoblasts: 130.2;dendritic cells: 56.4;Extravillous trophoblasts: 124.3;Fibroblasts: 59.5;Hofbauer cells: 241.2;Syncytiotrophoblasts: 160.3" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 256.2;MCF7: 338.4;RT4: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" 236.7 186.0 29.1 33.8 34.1 60.4 223.6 33.7 40.9 123.7 37.9 126.6 55.4 105.6 20.9 155.7 106.6 36.0 125.5 27.7 31.3 115.7 82.7 129.6 29.6 37.1 32.5 63.6 182.3 21.1 34.2 57.7 35.7 275.8 29.3 5.3 166.8 35.0 91.4 198.4 85.2 25.1 33.4 94.8 111.1 565.0 33.1 34.2 85.0 24.8 18.2 122.8 124.9 38.7 107.9 256.2 10.0 0.0 112.2 73.8 163.2 78.9 43.4 31.3 30.4 50.9 172.4 0.1 48.7 38.6 0.2 100.7 6.2 60.1 8.5 5.7 4.6 4.3 92.6 43.8 160.5 0.1 39.0 97.0 64.5 43.3 40.0 12.7 63.0 0.0 0.1 0.1 15.9 338.4 0.7 28.7 16.0 77.8 58.0 42.4 0.0 21.0 51.0 239.0 3.0 1.0 99.8 122.3 0.4 34.6 187.0 32.6 63.1 0.3 29.6 46.2 15.6 25.0 39.4 0.4 8.6 0.3 25.4 84.0 127.6 29.3 51.3 76.4 46.3 16.8 49.6 38.0 117.2 21.7 34.9 38.2 46.6 61.2 69.4 58.2 78.1 72.1 29.1 34.1 33.7 40.9 27.7 31.3 37.1 32.5 35.7 33.4 33.1 38.7 58.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 130.2 56.4 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 124.3 59.5 0.0 0.0 0.0 0.0 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 160.3 6.5 0.0 0.0 0.0 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 433.4;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040523: AB_2677021, HPA076040: " "unprognostic (1.51e-2)" "unprognostic (1.19e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (9.35e-2)" "unprognostic (2.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.28e-2)" "unprognostic (2.98e-2)" "unprognostic (5.40e-2)" "unprognostic (7.39e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (3.91e-2)" 40.7 47.5 27.5 16.9 28.2 27.3 34.1 32.6 37.3 33.3 32.6 41.2 20.0 30.4 31.4 26.6 28.2 23.0 56.9 27.4 29.6 39.4 46.0 31.3 27.0 27.6 27.8 35.6 23.3 45.6 31.1 24.2 28.6 26.6 29.1 22.3 22.4 29.3 43.0 22.6 26.2 27.4 27.5 25.9 29.9 65.8 29.0 28.5 28.8 72.6 31.0 30.6 29.9 31.8 41.0 40.8 4.7 0.5 73.4 140.7 0.9 33.4 76.8 48.7 46.4 0.5 44.2 21.1 17.6 106.7 35.2 27.8 15.4 32.2 48.5 81.2 26.8 26.7 16.1 27.5 139.6 0.1 21.2 85.1 92.9 36.6 42.6 93.6 49.2 37.8 0.4 13.3 100.1 39.4 106.6 4.2 6.4 53.6 20.6 26.0 0.1 6.1 79.4 21.1 29.0 56.2 26.0 37.2 52.6 2.4 37.9 46.4 38.6 38.7 17.0 17.5 52.6 10.6 0.7 8.2 53.4 16.6 44.3 33.3 38.0 31.9 30.2 35.3 33.8 38.5 35.2 34.6 49.6 32.7 27.2 30.9 23.0 37.6 42.8 52.4 46.0 25.6 27.5 28.2 32.6 37.3 27.4 29.6 27.6 27.8 28.6 27.5 29.0 31.8 44.4 32.1 26.2 25.1 53.7 89.9 100.5 92.4 21.6 33.6 41.3 51.2 45.4 52.9 40.1 49.7 12.5 74.2 65.0 36.2 92.0 68.9 433.4 49.9 56.9 30.1 25.7 41.4 43.2 76.9 109.8 73.5 16.8 50.1 36.8 74.0 36.4 53.1 87.4 42.1 35.1 28.6 42.7 78.2 95.2 503.0 93.8 66.3 92.5 19.7 116.8 44.0 80.3 23.1 44.4 90.5 37.3 73.0 38.5 75.6 68.0 138.8 42.7 57.4 98.6 82.8 75.2 243.2 48.8 41.4 95.8 44.5 64.9 87.0 47.5 89.5 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899162-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.5;lymphoid tissue: 244.1" "Cell type enhanced" "Detected in many" "B-cells: 225.8;dendritic cells: 492.3;Kupffer cells: 105.1;Langerhans cells: 366.0;Macrophages: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2477.4" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2477.4" "Group enriched" "Detected in some" 4 "Daudi: 240.7;THP-1: 382.3;U-698: 928.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013480: AB_2533439, HPA002267: AB_1079143, HPA002531: AB_1851904" "unprognostic (2.09e-3)" "unprognostic (7.51e-2)" "unprognostic (5.16e-2)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (3.46e-3)" "unprognostic (3.19e-2)" "unprognostic (5.31e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (5.31e-2)" "unprognostic (3.14e-3)" "unprognostic (3.97e-2)" "unprognostic (9.66e-3)" "unprognostic (4.04e-1)" "unprognostic (1.10e-2)" 25.9 7.6 4.7 81.4 5.6 85.5 9.3 7.0 6.2 5.6 5.4 27.1 47.1 8.0 3.1 6.7 6.5 19.7 3.8 6.3 5.4 6.1 36.9 27.4 244.1 9.5 8.5 2.5 3.4 1.7 1.7 10.1 10.0 7.7 33.5 0.8 7.1 8.9 2.0 5.0 56.2 13.5 11.3 137.3 22.9 4.8 12.6 61.5 4.1 1.7 224.9 21.8 1.6 14.0 0.9 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 26.0 0.0 240.7 1.5 0.0 0.0 0.1 1.4 0.0 0.2 0.2 2.7 0.1 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.5 0.0 0.0 0.6 21.3 0.2 20.6 0.0 7.5 1.1 27.2 0.0 0.0 0.1 0.1 1.0 0.0 0.2 1.4 0.0 382.3 0.6 0.0 10.9 0.2 0.9 0.3 0.3 928.2 0.0 128.4 0.0 9.1 137.1 3.4 3.3 134.3 4.5 347.0 1.8 2.1 291.2 361.3 3.5 2.8 8.4 111.5 97.3 2477.4 0.7 150.1 4.7 5.6 7.0 6.2 6.3 5.4 9.5 8.5 10.0 11.3 12.6 14.0 3.7 0.0 4.2 0.0 225.8 10.5 0.8 0.0 0.6 0.0 2.4 3.4 1.5 2.8 1.3 0.0 0.0 0.8 492.3 13.0 1.9 0.5 1.5 7.3 7.6 7.6 28.7 7.4 0.6 1.4 5.7 10.8 15.3 12.5 2.5 0.4 1.8 6.5 64.1 0.0 0.2 11.8 0.0 105.1 366.0 4.6 0.3 122.2 44.4 33.7 35.3 0.4 23.7 1.0 0.4 0.1 10.7 0.0 14.1 2.3 34.2 3.5 0.0 0.2 6.6 0.7 6.7 0.7 6.7 0.4 9.2 1.1 23.1 48.8 25.6 2.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 284.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.2;Proximal tubular cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 270.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "HPA043142: AB_10794653" "unprognostic (2.74e-1)" "unprognostic (8.38e-3)" "unprognostic (7.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-1)" "unprognostic (3.09e-1)" "unprognostic (5.82e-2)" "unprognostic (8.59e-2)" "unprognostic (9.90e-3)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.20e-2)" "unprognostic (2.09e-2)" 50.4 55.6 39.7 20.0 41.2 21.4 38.3 42.7 52.4 25.4 48.1 62.1 36.2 28.4 8.1 52.2 25.8 17.2 69.5 39.5 43.9 101.4 284.3 26.4 19.2 46.6 44.4 23.3 44.4 39.9 46.3 9.3 43.7 40.9 16.3 3.3 41.8 28.7 95.7 37.6 37.2 16.8 42.6 50.8 41.4 65.6 42.1 9.9 39.1 49.0 14.0 41.6 30.3 44.4 52.8 78.1 20.1 55.6 13.6 28.4 67.7 37.9 36.7 45.7 46.4 40.0 88.2 98.6 66.2 42.2 44.0 51.1 39.7 46.6 14.6 38.9 270.2 57.6 17.8 128.0 55.6 63.2 163.5 42.5 44.2 29.4 22.0 20.4 42.4 39.3 93.6 61.1 28.9 101.9 0.3 73.6 32.4 113.2 217.9 72.1 44.4 126.0 75.0 47.7 24.7 70.5 35.5 75.3 41.4 11.9 63.8 109.4 32.4 34.0 48.5 38.8 44.7 78.7 73.0 78.7 52.2 79.4 58.3 0.7 16.0 0.9 12.7 33.8 12.6 18.7 11.6 16.2 29.5 12.6 11.5 11.8 0.7 24.3 27.8 24.1 15.2 15.0 39.7 41.2 42.7 52.4 39.5 43.9 46.6 44.4 43.7 42.6 42.1 44.4 25.4 6.4 6.3 5.5 38.0 59.5 65.3 148.8 32.5 12.5 51.7 56.5 20.8 48.6 50.3 62.5 2.1 32.5 19.1 200.1 162.4 65.1 44.5 37.8 39.0 36.9 71.3 46.9 3.5 68.1 105.5 44.2 63.7 25.1 45.2 43.2 28.5 272.2 96.0 13.5 5.4 225.4 87.5 44.5 50.6 43.6 38.8 39.0 62.2 2.8 28.0 53.1 21.6 6.6 12.8 56.4 125.8 30.9 80.5 128.7 253.7 479.9 26.1 10.0 26.3 32.0 39.0 183.8 16.4 69.6 68.6 21.6 19.4 123.4 190.7 74.8 KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041964: AB_10795647" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (3.74e-3)" "unprognostic (6.40e-3)" "unprognostic (8.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (8.85e-2)" "unprognostic (1.37e-3)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "unprognostic (4.70e-1)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" 7.3 13.4 14.4 6.2 13.6 3.5 4.4 13.1 14.3 5.8 8.7 6.5 5.0 5.0 9.2 9.6 6.2 7.9 6.3 13.7 14.3 5.5 15.9 6.7 5.4 14.7 16.3 13.7 3.5 5.7 5.9 7.7 15.0 4.2 4.8 4.3 5.8 5.2 8.5 4.9 4.5 7.1 12.4 4.6 4.5 4.0 14.6 5.9 11.2 7.0 6.2 7.1 5.9 14.7 5.2 11.8 6.7 5.0 23.8 16.9 4.1 10.1 9.6 7.1 7.1 11.1 7.8 5.0 9.9 11.4 9.5 10.1 6.5 8.4 7.3 6.9 3.9 3.8 15.4 9.8 13.2 2.4 4.7 16.4 15.4 15.5 8.8 14.8 11.0 6.1 8.1 4.5 9.7 7.3 3.8 7.3 3.0 19.0 8.9 5.0 5.1 3.1 8.3 9.3 4.6 7.1 6.4 4.6 4.9 12.1 10.6 2.6 12.9 11.3 11.0 30.0 3.9 8.6 9.2 4.8 5.9 3.9 6.4 2.0 5.4 7.5 0.9 6.0 1.4 0.6 1.4 1.7 3.7 1.4 1.3 1.0 8.3 1.4 5.1 0.8 1.1 2.2 14.4 13.6 13.1 14.3 13.7 14.3 14.7 16.3 15.0 12.4 14.6 14.7 1.9 0.0 2.7 4.6 0.7 1.8 1.2 1.5 0.6 1.7 2.4 2.2 3.5 5.7 2.0 0.0 0.0 1.2 0.6 2.8 1.9 1.5 0.3 1.4 2.5 2.3 0.0 0.0 4.1 2.2 1.1 2.8 1.1 1.9 5.7 7.0 3.6 7.4 2.3 6.7 3.4 1.3 0.0 3.1 1.1 0.5 4.4 1.3 1.8 4.7 2.8 1.0 0.0 4.0 4.2 2.5 1.7 9.1 1.0 1.9 2.3 2.7 1.1 0.9 0.0 1.2 2.9 1.5 2.7 3.6 1.4 1.9 1.8 3.8 1.7 2.1 LBHD2 ENSG00000283071 "LBH domain containing 2" A0A0U1RRK4 14 103084210-103090027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.9;testis: 3.0" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.3;Proximal tubular cells: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: Fibroblasts - ECM organization" 1.7 0.0 1.9 0.2 3.6 0.0 0.5 0.8 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 4.4 0.3 0.0 0.0 0.1 3.6 1.6 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.1 3.0 11.9 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.6 0.8 2.1 3.1 4.4 3.6 1.6 3.9 0.9 11.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;ovary: 2.1;testis: 2.2" "Cell type enriched" "Detected in some" 22 "Theca cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009814 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 52: Non-specific - Transcription" "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 1.3 0.8 0.3 0.0 0.4 0.0 0.7 0.9 0.5 0.0 0.7 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.1 0.0 3.2 0.7 2.1 0.0 0.0 0.5 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 2.2 0.8 0.2 0.6 0.1 0.0 0.3 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.9 0.5 0.2 0.6 3.2 0.7 2.0 1.6 0.8 1.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.3 1.0 1.2 0.1 0.0 6.5 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 143.2 0.0 0.0 LMO3 "DAT1, RBTNL2, Rhom-3" ENSG00000048540 "LIM domain only 3" Q8TAP4 12 16548372-16610594 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.7;intestine: 85.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Alveolar cells type 2: 210.2;Astrocytes: 293.8;Excitatory neurons: 226.2;Oligodendrocyte precursor cells: 112.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 32.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "ASC diff: 189.3;LHCN-M2: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.67e-2)" "unprognostic (2.84e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.10e-7)" "unprognostic (3.62e-2)" "unprognostic (5.44e-2)" "unprognostic (6.56e-3)" "unprognostic (4.91e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-5)" "unprognostic (4.41e-2)" "unprognostic (1.61e-1)" "unprognostic (2.13e-3)" "unprognostic (4.83e-2)" 27.1 8.0 72.8 2.3 89.5 0.0 13.4 35.0 93.7 38.2 25.9 85.6 1.0 18.4 2.7 2.6 7.3 5.2 6.5 85.4 43.5 3.0 0.4 33.8 0.2 42.4 61.9 8.6 39.3 0.7 20.3 1.1 48.2 13.1 9.7 2.7 3.2 28.6 1.6 1.9 14.0 11.3 40.8 0.5 7.1 0.9 67.1 15.3 50.6 1.7 0.0 54.9 18.5 59.2 0.0 0.0 0.2 0.1 189.3 7.4 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.2 0.0 0.0 0.8 0.6 2.5 0.0 0.0 4.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 91.9 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.3 14.3 0.0 0.0 0.0 0.2 0.8 0.0 0.7 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 89.5 35.0 93.7 85.4 43.5 42.4 61.9 48.2 40.8 67.1 59.2 8.3 173.1 210.2 293.8 0.1 0.3 0.2 5.8 0.0 0.3 2.8 1.4 1.1 0.0 62.8 53.3 18.8 0.2 0.1 0.0 3.9 0.0 5.7 1.8 0.4 0.3 0.0 0.0 226.2 3.6 0.0 23.5 0.0 0.1 5.1 2.5 0.0 0.0 0.2 0.0 46.8 0.0 8.2 0.0 0.5 0.8 0.9 0.7 3.6 18.7 0.0 0.8 0.0 112.6 7.0 0.5 0.0 0.4 0.1 0.2 0.0 0.1 63.7 0.6 0.0 6.3 10.4 1.7 0.8 0.2 0.1 0.3 0.6 0.0 0.0 0.2 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528136-220664461 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 73.8;Excitatory neurons: 171.3;Inhibitory neurons: 170.1;Oligodendrocyte precursor cells: 167.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 11.3;RT4: 33.7;SuSa: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 6.3 1.8 6.9 1.4 7.1 0.0 4.9 6.4 10.0 4.6 8.4 5.4 0.4 4.2 9.7 4.8 3.3 1.7 8.0 7.4 6.7 2.3 0.3 3.1 0.5 6.4 6.8 1.7 0.9 2.4 6.9 1.1 7.4 3.0 1.2 9.3 3.7 4.0 2.2 2.5 2.5 3.9 5.7 1.3 2.8 6.9 6.5 1.4 4.3 3.5 1.9 5.3 5.1 6.4 0.4 0.0 5.4 1.1 0.0 0.0 1.8 1.6 2.2 1.8 2.5 0.0 0.0 0.0 0.0 0.0 2.5 2.5 11.3 6.0 1.0 0.0 8.4 0.0 2.3 0.0 0.0 0.7 0.8 0.9 4.7 0.0 3.0 0.8 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 8.1 5.5 1.8 0.0 7.4 0.0 0.0 33.7 6.4 6.2 0.3 0.3 0.5 12.2 0.5 0.0 0.0 0.0 2.4 4.0 7.1 0.0 0.0 0.0 1.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.1 6.4 10.0 7.4 6.7 6.4 6.8 7.4 5.7 6.5 6.4 3.2 0.0 0.5 73.8 0.5 3.4 2.6 10.0 13.1 28.6 1.6 3.8 21.9 0.0 4.7 3.7 31.3 2.1 0.0 0.7 0.0 1.6 7.3 19.3 6.4 3.4 9.0 0.0 171.3 0.0 2.3 6.3 2.6 35.5 0.0 13.6 3.3 0.0 0.3 10.1 170.1 0.4 4.1 0.3 1.5 3.6 2.1 0.2 0.0 15.0 0.0 12.3 0.0 167.9 45.9 0.1 0.0 6.4 0.6 4.8 1.5 0.2 4.1 11.9 0.0 6.9 17.5 17.4 5.1 13.1 3.3 1.0 0.4 1.1 0.9 4.8 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 709929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 73985.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" 27287.7 50118.4 114427.0 5960.9 114629.6 9211.1 23112.5 102567.5 164780.5 8637.9 123709.0 47542.8 18239.3 10045.0 10813.1 24529.5 11015.1 5914.4 210840.8 108795.0 110116.5 112074.1 105449.6 14032.6 6314.3 129884.9 115346.3 7950.6 24515.9 29782.0 16861.9 10397.8 125082.8 25688.4 24989.1 8983.3 21379.6 12907.0 93258.6 22997.0 36121.9 9693.6 102620.8 18194.3 45409.4 14516.5 123032.8 6034.4 16877.7 109930.2 7889.2 21068.8 13184.5 102646.5 6276.2 9796.4 12777.6 12396.3 25548.5 9745.3 9393.2 7927.6 6429.8 4420.4 6584.3 10616.0 13681.5 12924.1 6467.6 11751.8 4522.1 23074.6 1724.1 16319.1 5925.8 10089.3 8726.0 9297.7 73985.8 20756.8 5543.0 7919.2 9987.0 14433.8 23568.7 2276.3 8072.8 14337.8 4979.3 12668.7 8862.9 12216.0 12212.6 13490.3 5804.8 22519.7 3353.4 12256.7 6160.6 5998.2 3899.6 10866.7 17578.2 17096.2 4758.2 7830.6 6527.3 15842.4 11881.3 18742.2 11084.6 31596.4 12345.0 10576.0 9043.3 10116.0 5740.6 6151.2 6563.0 7590.8 5638.0 15586.1 7129.7 20953.0 13541.7 15753.7 5586.8 8887.6 6782.0 11844.8 6189.5 6338.9 6316.7 10947.0 6386.1 7947.1 5329.9 6846.5 10055.3 8426.1 5367.4 7670.7 114427.0 114629.6 102567.5 164780.5 108795.0 110116.5 129884.9 115346.3 125082.8 102620.8 123032.8 102646.5 4337.7 1445.5 1999.8 0.0 11825.3 6754.0 8961.4 22171.6 22140.9 0.0 11994.6 16742.4 709929.9 18464.2 10323.3 18597.6 0.0 0.0 7569.1 29582.2 3709.5 3684.4 1119.7 12108.5 6979.9 16215.0 6396.9 27238.9 0.0 4873.7 0.0 10942.5 19089.4 20683.3 2144.6 17185.5 15141.7 53416.5 0.0 0.0 0.0 17158.1 14290.0 26774.7 4814.0 5284.9 7663.3 9292.7 5140.4 0.0 7967.0 0.0 6828.1 0.0 0.0 4709.1 15133.6 5123.0 14109.6 5949.4 40280.5 22569.2 7617.1 0.0 7060.4 9361.8 14171.2 7120.5 8965.1 26952.2 6702.8 0.0 8863.0 13639.8 19371.4 14261.8 MT1A "MT1, MT1S" ENSG00000205362 "Metallothionein 1A" P04731 16 56638666-56640087 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 488.0;liver: 430.8" "Group enriched" "Detected in many" 6 "Adipocytes: 797.9;Fibroblasts: 244.1;Hepatocytes: 343.8;Skeletal myocytes: 561.9;Smooth muscle cells: 889.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.4;ASC TERT1: 27.9;HHSteC: 19.7;HMC-1: 29.5;hTEC/SVTERT24-B: 80.2;NTERA-2: 40.1" "Low region specificity" "Detected in single" "CAB002161, CAB013056" Approved NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "CAB002161: AB_563878, CAB013056: " "unprognostic (1.36e-1)" "unprognostic (4.91e-3)" "unprognostic (1.22e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (6.67e-3)" "unprognostic (3.10e-2)" "unprognostic (1.86e-1)" "unprognostic (9.43e-2)" "unprognostic (1.35e-2)" 488.0 64.3 9.8 10.8 12.3 0.0 208.1 9.8 14.1 62.0 8.2 28.9 7.7 13.6 1.3 33.4 68.7 30.2 63.3 9.3 10.7 136.8 430.8 115.2 0.6 10.6 10.8 19.8 90.3 2.1 25.9 0.7 11.7 33.1 13.1 4.4 18.9 2.9 100.0 26.1 23.4 16.9 11.5 3.4 42.9 8.4 10.8 6.1 67.7 6.1 0.7 34.0 22.6 9.7 0.0 6.2 0.0 0.1 18.4 27.9 0.4 1.9 7.9 1.2 1.5 2.3 4.8 0.0 2.4 1.1 0.0 0.5 0.0 0.4 2.9 0.0 0.0 0.0 2.5 9.9 19.7 0.2 29.5 8.2 0.0 80.2 0.0 0.0 7.7 0.0 0.7 0.0 5.5 0.0 0.0 0.1 40.1 0.0 0.0 0.0 0.0 3.6 0.5 0.0 0.3 0.1 0.0 0.3 0.0 0.9 0.0 0.3 6.3 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 9.8 12.3 9.8 14.1 9.3 10.7 10.6 10.8 11.7 11.5 10.8 9.7 797.9 9.6 1.7 0.7 1.8 27.4 11.3 1.9 5.7 0.0 11.7 15.4 5.4 8.6 5.1 0.0 0.0 1.1 1.0 11.1 13.7 2.7 0.1 11.9 6.9 63.2 3.6 29.5 0.0 1.8 12.8 244.1 5.1 23.8 3.8 0.3 15.7 343.8 0.3 0.0 0.0 32.3 0.0 10.4 39.6 0.7 55.0 12.4 33.8 0.0 0.0 0.0 0.0 0.0 0.0 3.0 18.6 12.8 1.2 27.9 86.5 16.1 3.0 0.0 26.3 561.9 889.5 0.0 0.3 2.1 19.5 0.5 6.6 0.4 34.7 13.7 MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 588.9" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 481.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 137.3;hTERT-HME1: 24.0;HUVEC TERT2: 28.3;OE19: 47.5;RT4: 25.1;TIME: 33.1" HPA039827 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" 65.3 54.7 2.0 2.6 2.4 4.0 22.3 6.3 1.8 17.3 1.3 18.1 16.8 29.4 1.8 41.4 4.7 4.8 588.9 1.8 2.5 5.7 2.4 31.8 6.0 6.7 2.8 5.1 35.1 0.6 1.7 56.6 7.7 19.8 11.8 1.3 18.3 38.2 11.6 9.6 15.4 17.2 1.6 12.4 23.4 2.5 3.5 1.4 3.7 15.5 8.6 84.1 26.9 1.7 6.0 1.7 0.0 10.5 2.3 0.1 3.2 0.9 8.6 1.4 1.7 7.3 4.1 0.1 0.7 0.0 8.9 2.6 0.0 4.4 1.7 0.0 0.2 137.3 1.7 0.1 0.4 0.0 0.1 0.0 3.1 0.3 24.0 0.1 28.3 0.2 1.9 0.0 0.7 2.3 0.0 0.1 0.1 47.5 2.4 0.0 11.4 0.3 0.0 25.1 0.0 4.1 0.6 5.9 0.0 1.2 7.9 0.1 33.1 0.1 2.6 0.4 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.0 3.4 2.0 0.0 0.5 0.0 0.8 0.0 0.2 2.4 2.0 2.4 6.3 1.8 1.8 2.5 6.7 2.8 7.7 1.6 3.5 1.7 22.9 9.6 0.6 0.0 0.3 0.0 10.2 0.0 0.0 0.3 3.0 1.0 481.4 5.7 0.6 25.8 0.0 4.4 0.0 26.9 7.9 32.5 0.1 1.1 3.0 15.1 1.8 1.3 0.0 18.9 2.4 9.8 7.1 3.5 0.0 65.1 4.6 0.2 1.4 0.0 0.0 7.9 0.0 7.9 0.0 0.7 4.7 8.7 0.0 0.0 3.4 0.6 0.0 0.0 0.0 21.5 24.9 17.0 0.0 11.0 18.1 0.3 0.7 0.2 0.0 0.2 8.1 0.0 1.6 0.0 0.0 1.2 0.2 13.2 6.6 22.4 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.6;Hofbauer cells: 54.4;Kupffer cells: 100.9;Proximal enterocytes: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 45.3;HSkMC: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" 60.7 19.9 11.3 19.4 11.8 3.3 51.1 11.2 14.3 25.3 10.2 24.6 48.4 13.6 17.6 7.6 20.3 19.6 18.5 10.3 11.1 23.4 83.8 24.1 46.7 11.0 12.1 15.2 16.7 6.8 7.2 25.4 11.7 19.4 12.0 2.2 14.8 11.5 9.1 11.7 41.0 7.9 10.5 53.2 16.3 21.8 13.8 11.0 20.3 6.3 13.6 22.4 17.5 11.5 3.5 13.8 6.4 6.1 41.0 45.3 31.1 3.5 17.9 5.7 8.8 17.0 43.2 6.1 6.5 2.8 2.1 9.2 7.6 6.1 3.8 5.8 6.1 8.3 18.7 26.1 17.5 2.9 1.0 61.2 3.7 8.7 5.5 9.7 5.0 9.4 10.2 2.5 4.5 14.8 5.8 17.0 7.1 18.7 4.5 8.4 8.3 4.1 5.0 31.9 6.1 2.3 12.2 7.9 10.4 6.1 19.5 8.8 1.3 4.5 6.1 9.1 2.0 11.9 18.3 7.6 8.2 3.9 2.2 7.8 2.7 2.5 1.4 13.3 1.9 1.0 1.5 1.3 4.3 0.7 1.7 1.4 1.6 5.8 4.2 0.7 3.8 1.9 11.3 11.8 11.2 14.3 10.3 11.1 11.0 12.1 11.7 10.5 13.8 11.5 27.2 0.0 11.3 8.1 3.0 3.3 8.6 4.6 2.2 2.4 12.7 12.1 6.6 15.7 4.9 5.5 2.1 11.0 1.5 24.4 11.7 5.8 31.0 2.4 15.3 12.5 1.8 7.0 9.2 8.7 13.3 14.1 17.9 2.8 13.3 7.1 24.7 66.6 54.4 1.7 10.9 14.6 2.0 100.9 3.3 49.0 9.0 24.7 3.6 1.0 5.4 4.4 2.1 3.0 5.6 4.2 10.7 6.0 2.4 4.1 69.5 26.1 2.5 0.8 19.7 7.4 16.3 32.4 16.8 3.0 2.4 6.6 2.1 5.4 19.0 6.3 OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 214.3;Oligodendrocytes: 433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.4" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040959: AB_10964295, HPA043401: AB_10960208" "unprognostic (1.75e-2)" "unprognostic (3.35e-2)" "unprognostic (9.84e-3)" "unprognostic (4.92e-3)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (5.88e-2)" "unprognostic (2.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "prognostic favorable (4.98e-13)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.18e-2)" "unprognostic (5.42e-3)" "unprognostic (1.56e-1)" 72.0 27.8 77.1 9.4 105.6 15.4 47.9 99.6 136.0 52.4 114.0 34.9 20.7 48.0 17.2 30.8 29.6 21.1 52.0 77.3 90.6 43.5 13.3 24.2 10.4 89.7 95.0 27.3 16.5 62.8 18.7 8.3 94.5 23.0 22.7 82.2 51.5 26.2 170.9 17.5 20.2 41.1 79.2 9.9 21.3 14.3 91.3 9.6 29.0 123.1 7.9 25.4 20.0 136.8 38.2 11.4 26.3 49.1 60.0 48.7 24.5 14.0 40.4 12.4 10.2 7.1 38.9 0.1 16.0 25.1 19.7 37.9 10.4 24.4 11.4 0.2 19.6 12.1 7.8 0.2 29.9 30.4 6.0 63.4 34.4 9.5 38.4 54.0 15.9 10.4 0.0 0.3 15.5 16.1 7.0 9.1 21.7 19.5 36.8 0.0 21.0 3.2 3.3 27.7 16.9 16.6 32.6 37.5 46.1 24.5 13.7 21.7 3.4 45.9 9.4 14.9 13.6 0.4 5.3 1.0 22.3 8.7 26.8 93.4 4.2 1.1 0.2 2.2 0.1 0.0 0.8 0.6 4.1 0.4 0.6 0.5 1.6 0.2 0.7 4.1 0.8 1.5 77.1 105.6 99.6 136.0 77.3 90.6 89.7 95.0 94.5 79.2 91.3 136.8 214.3 16.0 21.6 142.0 5.4 20.1 43.4 16.6 29.6 66.6 73.6 64.3 78.0 41.5 20.0 20.2 22.9 12.1 11.1 23.6 64.6 13.3 67.7 27.6 55.3 89.9 4.8 18.7 180.3 7.4 8.1 59.9 16.3 17.0 17.2 137.9 37.5 12.4 26.6 25.2 166.4 40.0 40.7 27.4 17.9 76.4 42.9 34.3 58.7 67.5 11.0 124.8 0.0 75.9 433.0 10.7 19.1 54.9 2.5 27.1 29.8 71.7 21.7 112.3 32.9 44.7 65.8 6.7 9.9 27.2 10.2 6.4 3.8 103.7 16.2 26.4 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 159.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4339.5;Excitatory neurons: 5259.8;Inhibitory neurons: 2489.4;Oligodendrocyte precursor cells: 6313.8;Oligodendrocytes: 14117.8" "Cancer enriched" "Detected in single" 8 "glioma: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cell line enhanced" "Detected in many" "AF22: 25.1;LHCN-M2: 41.6;TIME: 48.9;U-698: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Centrosome" "HPA015581: AB_1855048" "unprognostic (1.77e-1)" "unprognostic (8.36e-2)" "unprognostic (9.12e-3)" "unprognostic (4.42e-5)" "unprognostic (7.54e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (8.47e-4)" "unprognostic (6.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.35e-4)" 3.8 2.2 37.1 0.4 84.0 3.3 1.0 41.5 53.2 0.9 0.0 1.2 0.2 0.2 1.2 0.3 0.4 1.5 4.9 37.8 51.3 2.5 1.5 1.5 0.7 49.9 52.1 0.6 1.3 0.0 2.0 0.0 56.8 1.6 0.5 9.4 0.3 4.2 1.3 0.2 0.5 0.5 27.1 0.9 1.9 0.9 76.1 2.2 1.0 1.1 0.6 0.7 1.0 159.3 0.0 19.3 25.1 0.0 6.6 5.1 0.0 3.8 0.2 2.7 1.0 0.1 0.1 5.7 0.1 2.9 0.9 0.0 2.1 0.6 1.2 0.0 10.1 0.3 0.2 0.0 6.3 0.7 0.3 12.1 0.7 3.1 5.0 0.6 2.1 2.2 0.6 0.3 41.6 1.6 12.2 0.0 0.2 0.5 2.5 18.2 0.8 0.0 0.5 0.0 3.2 1.3 0.0 0.1 0.3 0.6 0.0 0.1 48.9 1.4 1.2 5.9 2.0 7.3 0.0 64.2 10.6 0.0 5.0 4.5 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 17.3 0.1 0.1 0.1 0.9 0.0 1.2 0.0 0.2 37.1 84.0 41.5 53.2 37.8 51.3 49.9 52.1 56.8 27.1 76.1 159.3 5.6 19.2 68.0 4339.5 29.1 1.9 2.5 0.0 1.8 318.8 9.2 14.7 152.5 0.0 4.4 5.5 20.9 0.2 4.3 0.9 9.8 1.9 3.6 0.3 6.4 4.7 62.4 2.5 5259.8 0.0 0.2 76.3 11.7 0.3 1.3 1.0 19.2 8.6 0.3 198.5 2489.4 1.4 0.0 1.9 1.4 3.0 29.5 3.7 10.6 237.0 0.3 87.8 2.1 6313.8 14117.8 0.3 1.2 14.7 1.4 2.0 0.0 0.8 0.0 27.1 6.6 27.9 25.4 6.8 5.4 1.2 0.3 0.0 2.7 3.7 0.8 0.8 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549601-54579239 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 76.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.6;Inhibitory neurons: 10.2;Kupffer cells: 13.0;Macrophages: 9.4;Sertoli cells: 13.1;Smooth muscle cells: 13.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 76.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 12.7;HMC-1: 14.9;NB-4: 10.7;THP-1: 9.0;U-937: 7.2" "Region enriched" "Detected in all" 6 "basal ganglia: 999.4" "Region enriched" "Detected in all" 7 "basal ganglia: 228.7" HPA018492 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 9.1 1.1 8.4 4.0 76.9 4.8 4.6 0.0 13.7 2.0 0.0 7.4 1.0 2.7 1.8 1.7 2.0 2.2 1.4 6.3 0.1 0.8 1.0 2.3 1.3 0.0 0.0 8.6 0.4 6.1 0.3 0.2 0.0 1.3 1.0 0.4 1.0 1.4 0.6 1.4 3.4 4.0 0.0 4.0 3.3 0.7 2.4 0.9 2.0 1.0 0.8 8.7 1.5 4.9 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 2.1 0.0 0.0 12.7 0.6 4.3 0.0 0.0 0.0 5.5 14.9 0.7 0.0 0.0 0.0 0.0 0.0 5.5 0.0 2.3 0.0 0.0 0.5 10.7 3.5 0.0 0.0 2.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 2.5 0.0 7.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 76.9 0.0 13.7 6.3 0.1 0.0 0.0 0.0 0.0 2.4 4.9 2.3 0.0 1.1 1.6 1.8 1.0 0.2 0.0 0.6 2.7 0.2 0.6 3.6 0.0 0.6 3.7 0.0 0.1 1.4 0.0 0.0 0.0 6.3 0.1 0.0 0.8 1.8 3.6 18.6 0.0 0.0 1.5 0.0 0.0 0.0 4.4 0.0 0.3 8.5 5.0 10.2 0.0 0.0 13.0 2.5 4.9 2.1 9.4 0.0 2.8 6.7 0.1 4.1 1.0 0.9 0.0 0.0 3.0 2.6 0.4 0.0 0.0 0.0 0.2 13.1 0.6 13.7 0.8 0.6 0.2 0.4 0.3 2.8 0.4 0.1 0.1 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 299.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria No No 61000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favorable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 59.9 76.5 48.7 42.2 50.2 25.7 42.9 53.9 62.7 43.3 63.6 56.8 42.5 38.5 44.6 57.4 37.7 35.9 175.0 49.7 52.3 100.8 110.7 36.4 53.1 51.7 49.4 26.5 36.4 88.8 44.1 57.0 51.5 48.5 60.4 30.7 45.9 52.1 272.6 36.8 37.6 63.8 51.6 42.8 53.9 42.3 53.1 53.1 40.8 299.4 56.0 49.7 35.9 54.3 66.5 90.9 92.3 69.8 91.7 111.1 110.4 81.6 101.3 117.9 120.6 165.1 62.6 140.3 44.9 103.8 109.0 37.6 113.2 74.9 90.0 81.7 83.0 125.4 163.7 126.0 92.5 103.0 67.9 97.9 67.7 95.5 55.8 137.5 103.1 114.2 65.9 61.5 129.5 63.1 98.2 107.8 127.2 69.2 101.3 46.3 71.8 136.1 188.1 89.1 63.7 70.2 75.6 107.2 85.4 131.3 159.0 108.7 76.3 62.9 83.7 66.8 94.2 85.2 129.9 99.2 96.2 120.8 60.7 57.8 98.9 98.7 83.2 115.1 87.9 102.2 81.7 80.5 141.1 103.4 90.9 82.4 19.6 129.4 109.7 94.7 113.2 124.1 48.7 50.2 53.9 62.7 49.7 52.3 51.7 49.4 51.5 51.6 53.1 54.3 57.8 60.9 34.5 5.9 45.3 27.9 40.7 142.0 26.7 31.8 29.4 31.6 300.6 48.6 96.0 35.0 25.0 174.1 35.3 41.0 230.9 95.9 76.3 37.0 37.3 58.0 58.0 22.5 10.9 72.2 101.6 54.1 29.6 34.2 39.3 48.5 46.1 76.1 84.6 57.2 13.3 50.4 162.8 37.9 26.6 16.9 60.3 37.2 56.9 9.4 76.5 61.7 70.0 9.0 13.6 55.9 43.0 51.1 38.8 19.1 45.8 146.8 70.7 45.9 65.7 30.8 72.3 98.2 88.3 42.8 29.8 157.2 44.7 224.4 53.0 37.7 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 753.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 22000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 223.2 200.1 127.6 148.5 132.0 260.4 198.0 136.9 146.2 134.6 127.1 180.3 132.2 163.4 102.9 191.0 140.5 91.3 266.2 131.9 137.0 168.9 214.0 170.3 164.9 134.0 131.7 134.4 140.2 114.1 104.1 115.0 136.7 117.8 108.0 54.5 129.2 104.2 753.9 136.6 151.3 117.1 134.7 163.3 152.9 61.3 136.4 188.0 121.9 375.3 155.4 168.2 141.3 143.7 532.8 674.6 390.9 419.4 357.2 277.8 345.0 398.3 343.6 1024.7 428.8 1785.8 504.0 438.2 926.2 421.0 644.1 627.2 371.9 752.5 497.0 261.0 261.1 1009.7 641.9 913.2 454.0 434.3 570.4 297.9 602.0 525.1 454.5 248.8 509.2 436.1 439.2 419.2 441.8 568.6 696.1 673.6 332.5 595.0 859.8 476.9 753.5 482.6 385.3 515.4 526.2 321.6 625.9 777.1 701.9 252.7 468.3 643.3 416.1 898.9 725.4 473.3 631.1 286.9 483.9 531.2 626.7 327.7 536.1 754.4 682.6 801.5 536.5 692.6 458.2 579.3 533.3 531.4 632.2 522.7 415.1 427.3 582.2 421.7 720.3 676.3 723.4 1131.2 127.6 132.0 136.9 146.2 131.9 137.0 134.0 131.7 136.7 134.7 136.4 143.7 402.9 211.5 180.8 20.9 252.3 374.5 350.6 616.4 167.4 127.5 223.0 296.4 304.9 327.5 369.2 257.5 73.0 666.2 309.5 375.2 498.9 581.9 355.5 290.2 345.4 397.3 232.0 439.4 19.2 727.7 775.7 321.9 132.0 276.5 251.4 304.7 335.5 787.5 807.0 82.4 18.4 325.6 453.7 435.7 453.1 211.0 334.6 414.8 368.2 18.7 598.4 219.3 377.9 15.1 28.9 663.3 386.4 293.8 234.5 639.7 455.1 759.6 288.8 122.5 230.1 237.0 659.7 81.4 126.3 291.9 309.3 852.6 310.4 410.0 386.9 438.7 RASA3 "GAP1IP4BP, GAPIII" ENSG00000185989 "RAS p21 protein activator 3" Q14644 13 113977783-114132623 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 55.0;Horizontal cells: 60.6;NK-cells: 48.4;Plasma cells: 40.0;T-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046759 Uncertain NA NA 1400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA046759: AB_10959887" "unprognostic (3.41e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.75e-1)" "unprognostic (6.15e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-3)" "unprognostic (4.01e-2)" "unprognostic (3.92e-1)" "unprognostic (2.02e-1)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.99e-6)" "unprognostic (8.98e-2)" "unprognostic (8.16e-3)" "unprognostic (5.08e-2)" "unprognostic (4.11e-2)" 32.2 3.5 7.6 10.9 8.7 12.7 23.2 6.5 9.8 24.4 3.8 17.0 2.9 13.7 1.1 4.9 19.2 4.6 12.9 8.5 8.3 11.2 5.0 19.3 15.6 9.6 8.9 7.6 10.8 0.7 15.2 5.3 9.3 11.3 2.7 2.6 6.8 3.6 14.2 13.0 15.8 4.7 8.0 22.6 9.4 5.9 10.0 9.0 14.4 4.2 7.7 18.5 15.0 14.6 3.8 4.6 20.2 5.8 19.2 21.3 0.0 14.8 22.1 13.1 10.9 0.4 11.6 0.4 8.2 24.1 10.9 0.0 3.0 7.0 10.1 0.9 1.3 29.4 14.1 0.1 9.7 12.3 2.5 19.2 1.4 12.7 9.1 16.2 22.3 0.6 2.2 3.3 19.9 5.1 27.1 20.5 4.3 3.2 6.8 13.6 7.4 60.6 11.9 0.1 2.9 2.1 3.5 15.2 7.5 8.3 3.8 44.7 30.5 19.7 5.4 7.2 16.2 0.1 0.0 0.8 25.7 11.9 32.1 16.7 4.5 6.4 16.9 7.6 12.8 5.2 15.6 17.0 3.0 3.9 16.3 16.4 2.5 12.7 15.3 1.0 19.2 16.9 7.6 8.7 6.5 9.8 8.5 8.3 9.6 8.9 9.3 8.0 10.0 14.6 5.3 0.0 4.2 27.1 20.6 3.7 1.2 0.7 2.2 7.9 2.0 4.6 7.5 1.5 3.5 1.8 0.0 0.1 55.0 0.3 0.0 1.1 1.5 7.8 13.3 9.3 3.0 5.5 25.6 2.0 0.2 15.2 3.6 5.1 26.0 1.8 3.9 2.4 9.3 60.6 12.2 2.6 2.0 15.1 12.1 0.7 8.7 19.6 10.6 36.5 11.4 1.3 48.4 17.6 27.5 12.5 0.2 3.8 40.0 1.6 0.1 0.4 13.2 3.5 0.0 18.9 11.5 8.6 5.4 0.4 4.8 0.5 45.2 2.5 0.7 1.6 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Vesicles" "HPA018247: AB_1856475, HPA055489: AB_2682832" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (2.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.40e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (9.97e-9)" "unprognostic (2.14e-1)" "unprognostic (3.61e-2)" "unprognostic (4.98e-2)" "unprognostic (2.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.13e-2)" "unprognostic (6.38e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (3.82e-2)" 37.0 16.9 18.0 16.6 19.2 30.2 25.2 20.0 19.4 17.1 16.4 21.5 18.7 16.1 14.0 24.9 13.9 17.7 21.6 17.6 20.4 24.5 18.5 19.3 20.5 20.4 21.3 21.6 14.2 24.0 10.0 28.5 21.3 14.9 17.0 16.1 14.2 16.9 17.4 29.8 16.2 21.9 19.5 17.3 15.1 17.5 19.8 18.8 16.7 18.9 21.8 19.0 18.1 21.3 37.0 16.6 21.3 23.3 110.7 74.6 33.0 33.7 68.6 44.8 47.2 12.7 23.9 23.0 18.9 52.6 71.8 21.7 40.1 22.2 36.8 37.6 28.3 22.1 19.2 14.7 135.6 26.0 23.9 66.7 55.2 48.0 61.9 35.4 47.5 24.5 22.9 44.9 65.7 10.2 19.0 14.7 27.2 15.9 28.0 18.1 37.6 15.6 31.6 42.5 11.1 16.5 27.0 20.0 73.2 47.5 18.3 19.5 42.5 54.3 22.4 60.0 29.2 35.0 60.5 26.8 50.5 29.1 28.8 0.5 2.4 5.5 1.7 2.3 2.9 3.3 2.6 2.2 2.3 3.6 2.2 2.1 5.9 1.7 1.8 8.4 2.5 1.6 18.0 19.2 20.0 19.4 17.6 20.4 20.4 21.3 21.3 19.5 19.8 21.3 31.2 32.1 28.0 6.5 42.1 111.9 47.1 19.2 40.9 20.0 31.0 25.0 22.2 24.3 16.1 12.9 12.5 84.9 38.4 30.3 11.7 55.7 56.3 32.0 26.6 34.3 14.4 24.0 7.4 48.1 57.7 39.4 12.2 42.9 16.5 16.9 35.7 14.2 72.1 38.7 8.3 10.3 20.3 34.4 65.0 49.8 30.7 49.2 53.4 9.4 63.3 43.4 10.3 7.5 15.8 47.0 14.0 37.2 20.1 47.3 21.5 30.4 15.0 22.8 19.7 28.1 37.5 24.7 28.5 46.1 140.5 224.1 23.3 18.6 12.2 51.1 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "kidney: 109.4" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 173.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 109.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 819.1;Cholangiocytes: 133.0;Distal enterocytes: 282.9;Ductal cells: 129.2;Proximal tubular cells: 211.0" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 6.1;HBF TERT88: 5.7;hTERT-RPE1: 6.0;RPTEC TERT1: 15.4;U-138 MG: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" 5.1 0.7 30.0 2.2 43.6 0.5 1.0 47.0 32.5 11.5 0.0 41.1 54.3 0.4 0.3 1.2 0.9 29.4 6.2 21.5 37.9 119.5 21.7 6.9 0.2 38.6 28.0 0.8 260.3 17.2 5.8 2.7 24.8 34.7 41.2 5.1 2.5 1.1 2.2 0.1 14.6 1.7 38.2 0.8 18.6 0.5 38.5 3.5 22.0 3.5 0.0 4.5 0.4 33.2 0.0 3.5 1.0 0.0 0.0 0.0 0.1 13.0 1.9 2.2 1.6 0.0 0.1 0.0 0.1 6.1 0.5 0.0 0.2 0.0 5.7 0.0 1.7 0.9 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.7 0.0 0.5 1.2 0.0 4.8 0.2 0.1 0.2 0.0 0.0 0.0 0.9 15.4 4.1 0.9 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.0 7.7 0.7 5.5 0.6 0.0 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 30.0 43.6 47.0 32.5 21.5 37.9 38.6 28.0 24.8 38.2 38.5 33.2 1.5 3.2 37.1 819.1 2.2 0.0 4.3 3.2 0.6 3.2 0.9 0.3 24.0 133.0 31.1 25.8 0.0 0.3 7.2 282.9 15.6 129.2 11.5 2.8 0.5 1.3 8.5 4.0 51.4 24.2 0.1 4.9 33.1 5.8 1.3 0.6 3.9 35.8 0.2 0.0 93.4 65.6 2.0 0.6 0.2 1.5 0.0 2.3 1.8 34.7 1.0 3.9 1.0 29.1 3.7 16.2 60.8 0.0 1.7 40.8 31.8 211.0 10.4 1.5 6.6 1.0 6.2 0.1 1.0 5.5 0.0 0.3 6.8 2.4 68.1 12.3 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SSB "La, La/SSB, LARP3" ENSG00000138385 "Small RNA binding exonuclease protection factor La" P05455 2 169791933-169812064 "Predicted intracellular proteins" RNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004643, HPA017287" Supported Approved Nucleoplasm NA NA 93000 "Cluster 42: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "CAB004643: AB_425691, HPA017287: AB_1852672" "unprognostic (5.58e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (9.05e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.99e-4)" "prognostic unfavorable (8.30e-8)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (9.81e-3)" "unprognostic (3.24e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (6.17e-6)" "unprognostic (9.92e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-3)" "unprognostic (2.38e-2)" 114.1 75.6 53.7 75.8 54.9 105.3 76.0 55.5 72.8 59.3 63.3 61.7 49.2 68.6 82.0 51.6 61.0 58.1 69.0 53.8 58.0 74.5 68.5 55.9 93.3 55.5 58.3 68.9 40.2 80.0 64.6 73.6 55.6 78.2 57.1 55.2 49.9 58.8 62.3 46.6 49.3 61.5 55.3 62.7 49.8 41.1 55.2 70.2 81.7 52.9 81.2 88.4 51.2 55.2 189.0 109.3 231.2 173.5 244.9 226.0 287.8 226.8 150.8 208.2 192.7 332.9 201.7 419.8 251.7 149.8 188.9 197.9 315.3 198.6 283.9 231.2 258.4 505.9 138.0 323.4 218.6 410.8 181.5 175.1 187.1 265.0 156.8 170.6 235.4 156.1 599.0 95.5 442.4 149.5 273.6 428.2 373.3 180.7 110.5 267.9 245.7 304.6 266.3 205.6 219.8 168.0 179.9 132.4 262.9 223.4 152.5 292.0 213.9 151.1 180.1 153.8 221.9 110.3 227.3 355.9 149.2 381.4 168.2 83.4 47.3 59.9 71.9 81.6 104.2 89.8 100.9 92.1 56.8 75.8 90.5 97.0 7.9 93.8 104.5 60.6 100.9 67.2 53.7 54.9 55.5 72.8 53.8 58.0 55.5 58.3 55.6 55.3 55.2 55.2 143.0 86.6 79.9 21.9 107.9 91.6 229.2 308.7 83.6 114.7 78.1 126.7 91.9 77.2 168.9 112.2 27.1 212.4 111.6 33.6 187.9 206.6 20.3 235.3 188.4 131.5 73.0 154.2 25.4 146.7 212.4 133.5 46.9 101.2 205.0 111.4 92.8 77.0 185.7 136.3 26.8 82.7 240.1 86.8 91.4 49.7 184.2 111.7 80.0 15.0 113.4 152.7 84.5 20.1 21.5 113.2 47.8 186.9 78.7 199.2 40.2 194.9 371.1 91.4 216.9 183.7 194.8 154.4 156.7 68.5 88.4 165.4 128.4 183.3 100.0 155.9 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 96.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 338.3;Inhibitory neurons: 543.3;Oligodendrocyte precursor cells: 128.2" "Cancer enhanced" "Detected in many" "glioma: 4.5" "Group enriched" "Detected in many" 5 "amygdala: 67.0;basal ganglia: 77.7;cerebral cortex: 96.8;hippocampal formation: 92.9;white matter: 44.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HMC-1: 4.5;NTERA-2: 3.3;SCLC-21H: 2.7;SH-SY5Y: 11.1;SuSa: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB079005: , HPA037012: AB_2675431" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (7.54e-2)" "unprognostic (9.87e-3)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (6.32e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (9.77e-2)" "unprognostic (4.89e-4)" "unprognostic (9.94e-2)" "unprognostic (7.35e-2)" "unprognostic (1.78e-2)" 7.0 3.1 67.0 0.4 77.7 0.1 7.1 3.8 96.8 1.4 0.0 2.3 0.4 2.0 1.0 0.3 1.2 0.4 1.0 92.9 2.9 1.5 0.0 1.1 0.0 13.4 0.0 1.5 0.5 4.1 3.4 2.8 10.8 0.5 0.5 7.8 2.4 0.2 0.9 2.5 1.6 1.8 0.0 0.6 1.8 3.6 15.3 0.1 0.2 0.4 0.0 0.3 1.3 44.9 0.0 0.2 0.0 0.0 1.8 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.2 1.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.2 0.0 0.0 0.0 0.0 0.2 2.7 11.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.0 77.7 3.8 96.8 92.9 2.9 13.4 0.0 10.8 0.0 15.3 44.9 43.4 0.0 0.0 7.8 0.0 0.0 0.4 0.0 0.6 13.9 0.4 2.4 1.4 0.0 0.0 0.0 6.2 1.7 0.1 0.0 0.0 0.0 0.6 0.2 0.1 4.5 0.0 0.0 338.3 0.0 0.4 0.9 0.0 0.3 0.0 0.2 0.7 0.0 0.6 13.5 543.3 0.0 0.0 1.8 0.0 1.8 0.0 0.3 0.0 4.7 0.1 2.5 0.0 128.2 8.3 0.3 0.0 0.0 0.0 0.3 0.0 2.7 0.0 3.7 0.0 0.7 0.7 4.9 6.9 0.0 0.0 0.8 0.1 0.1 0.0 0.2 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 999.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" 12.8 12.0 5.7 4.4 9.2 6.7 12.1 6.8 8.3 6.8 6.3 14.2 16.4 8.9 6.8 6.0 7.0 6.2 13.9 5.7 7.2 18.3 59.5 10.5 4.0 8.5 8.5 10.6 8.3 6.3 10.1 3.9 8.5 7.2 6.9 7.1 7.2 3.3 7.6 6.6 14.6 4.2 5.8 6.3 10.1 34.9 8.8 3.3 7.9 3.7 2.1 7.5 6.1 15.4 12.9 14.7 13.0 9.6 16.6 12.5 15.6 3.8 11.1 7.2 10.5 4.7 39.9 4.1 11.8 3.6 27.4 11.5 3.6 7.8 3.8 6.5 9.2 4.7 6.0 22.7 16.5 3.7 16.6 14.8 11.9 14.4 3.1 7.9 4.0 9.1 2.0 5.1 4.3 7.7 4.5 11.2 7.6 9.9 8.5 6.8 1.8 40.0 21.6 13.4 9.0 8.7 4.1 15.7 21.3 9.3 4.8 9.9 1.7 5.3 8.8 7.5 4.7 3.7 4.7 2.3 13.6 9.6 6.3 14.1 12.9 6.3 7.3 23.1 6.3 13.9 7.4 6.3 6.6 14.8 3.5 4.5 1.4 7.8 16.2 99.4 8.1 7.6 5.7 9.2 6.8 8.3 5.7 7.2 8.5 8.5 8.5 5.8 8.8 15.4 10.9 6.4 12.0 8.1 3.5 1.7 9.5 24.2 1.8 6.9 9.0 7.6 35.5 10.0 20.4 20.2 4.2 14.5 9.5 53.1 45.0 18.6 188.3 14.0 4.6 8.5 14.4 10.1 2.9 25.7 15.5 6.9 8.2 5.7 6.3 8.6 10.0 93.0 34.3 18.5 3.6 22.6 44.7 12.6 0.7 999.9 9.0 14.0 8.8 1.9 3.8 17.1 5.2 3.0 4.8 17.5 51.3 12.4 2.6 8.9 74.3 45.9 32.8 13.8 26.3 3.7 10.6 15.6 13.2 3.9 2.3 9.3 3.7 8.3 18.0 12.7 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 UFSP1 UFSP ENSG00000176125 "UFM1 specific peptidase 1 (inactive)" Q6NVU6 7 100888721-100889715 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 7.9;Proximal tubular cells: 7.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027099 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027099: AB_2214069" "unprognostic (8.56e-2)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (3.55e-3)" "unprognostic (5.71e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" 2.0 2.7 1.2 0.9 1.3 0.6 1.6 1.9 1.7 1.5 0.2 1.8 1.0 2.4 1.3 1.9 1.8 0.1 1.6 0.9 1.2 2.1 3.1 1.0 0.6 1.4 1.5 0.9 3.1 1.0 2.3 0.4 1.4 1.8 0.5 0.3 1.7 1.0 3.7 1.1 1.5 0.8 1.2 1.6 1.9 0.7 1.1 0.8 1.4 1.2 0.4 2.1 1.1 1.5 2.9 3.7 0.8 3.8 3.6 2.1 2.3 2.2 0.7 0.9 0.6 1.5 2.0 0.7 1.7 1.8 1.4 5.6 1.1 1.3 0.5 2.6 8.2 2.4 3.2 1.8 3.6 1.0 1.1 2.4 1.6 1.2 4.6 1.0 0.3 1.4 3.7 1.7 1.4 7.3 2.4 6.0 2.8 3.0 5.1 1.2 1.1 5.8 1.6 1.3 2.6 4.3 4.4 5.6 2.7 1.1 1.4 0.9 0.9 2.4 2.5 2.6 1.7 1.7 2.2 0.2 0.8 2.0 2.8 0.0 2.4 1.5 3.1 2.1 3.5 1.0 2.6 1.7 2.9 3.9 2.9 3.6 0.4 3.0 2.2 4.4 1.2 1.7 1.2 1.3 1.9 1.7 0.9 1.2 1.4 1.5 1.4 1.2 1.1 1.5 0.7 0.0 0.0 0.0 0.8 0.6 2.3 1.3 1.8 0.4 1.4 1.3 0.8 1.5 0.7 1.8 0.0 2.4 0.8 2.5 7.9 2.2 0.3 2.2 3.6 0.8 3.0 0.8 0.3 2.1 1.2 1.2 1.1 1.2 0.0 0.6 1.8 4.7 1.9 0.0 0.3 2.2 0.0 0.8 0.7 0.4 1.8 0.6 0.0 1.0 0.5 2.5 0.0 1.0 0.2 1.8 5.0 1.9 1.3 3.2 1.6 7.4 0.7 1.0 6.6 1.5 1.5 0.2 0.3 2.4 1.0 1.6 0.8 4.4 2.5 2.2 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 297.7;skeletal muscle: 311.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1792.1;Hepatocytes: 2200.3;Proximal enterocytes: 2007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" 71.0 80.2 74.9 20.6 79.6 39.7 60.5 79.4 103.7 46.8 78.6 91.7 59.7 46.4 18.4 71.6 43.6 25.0 297.7 76.4 76.7 103.4 136.4 48.7 27.4 76.5 77.7 35.5 49.5 46.8 62.7 24.1 76.6 62.0 22.8 13.8 53.9 30.9 311.8 50.4 62.6 22.6 75.6 60.9 77.2 24.7 78.3 24.1 52.6 109.7 19.3 60.9 51.4 79.0 68.9 75.7 34.7 74.5 60.8 40.7 79.9 54.3 45.4 55.5 48.8 121.5 47.3 47.4 51.8 41.8 12.3 46.8 55.5 61.0 26.5 65.0 163.1 40.6 87.3 114.0 60.6 66.1 57.9 62.8 62.6 35.2 41.6 28.6 50.8 66.9 94.8 73.1 36.2 111.5 67.7 72.4 94.8 59.2 176.0 40.4 36.2 148.9 74.6 158.4 69.6 65.9 39.3 86.4 99.7 27.9 59.3 65.1 66.7 44.3 30.0 129.9 57.7 110.4 101.2 54.4 82.6 69.9 64.8 619.6 421.3 521.9 282.7 367.9 287.1 390.0 341.7 316.6 360.5 333.8 324.3 314.1 496.7 273.7 354.9 448.4 407.7 872.4 74.9 79.6 79.4 103.7 76.4 76.7 76.5 77.7 76.6 75.6 78.3 79.0 300.4 269.2 379.1 20.5 287.6 0.0 189.6 0.0 206.6 135.2 715.6 798.8 1731.6 529.0 159.7 634.5 39.6 481.8 380.1 834.6 1792.1 665.4 178.2 290.5 220.2 282.4 452.6 451.6 17.8 811.6 632.1 262.0 342.0 243.5 199.3 152.6 463.3 2200.3 962.9 89.2 17.6 681.7 0.0 783.5 0.0 474.8 252.8 472.2 0.0 10.3 866.6 418.8 568.5 9.5 25.1 855.3 727.0 259.5 384.1 365.5 2007.4 1742.3 267.5 164.4 223.5 192.6 291.3 159.2 145.3 520.3 0.0 512.8 304.3 188.0 717.0 290.3 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4