Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 AADACL3 ENSG00000188984 "Arylacetamide deacetylase like 3" Q5VUY0 1 12716110-12728760 "Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "placenta: 1.6;skin 1: 1.2" "Cell type enhanced" "Detected in single" "Extravillous trophoblasts: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Skin - Cornification" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (3.01e-1)" "unprognostic (2.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AAGAB "FLJ11506, p34" ENSG00000103591 "Alpha and gamma adaptin binding protein" Q6PD74 15 67200667-67255195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039371, HPA040174" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Cytosol" "HPA039371: AB_10805476, HPA040174: AB_10805605" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (8.25e-2)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.84e-2)" "unprognostic (4.52e-2)" "unprognostic (9.10e-2)" "unprognostic (5.28e-2)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.88e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (1.53e-1)" 15.1 19.1 10.5 19.2 13.3 19.8 22.5 7.2 14.5 17.9 12.7 27.8 15.8 14.8 25.9 20.5 16.5 18.5 15.8 12.9 15.7 27.4 18.1 15.6 19.9 9.8 11.5 8.0 17.0 35.2 19.0 15.8 11.5 18.8 33.8 22.1 15.4 20.5 32.8 12.9 19.5 21.2 9.5 15.4 23.9 21.9 15.7 29.9 33.0 23.0 25.9 27.5 13.2 12.2 49.7 89.9 63.2 64.8 60.0 49.3 31.1 51.4 74.7 60.6 68.7 66.8 52.9 48.1 51.1 52.9 74.4 98.2 129.9 59.4 62.9 65.0 62.0 46.2 63.2 26.8 66.0 78.8 51.2 48.6 80.6 45.8 94.3 41.0 47.8 59.7 96.5 63.7 60.2 61.3 47.6 32.7 53.1 61.7 31.5 53.1 81.1 57.7 55.9 116.1 89.7 57.3 60.7 44.0 75.7 54.7 71.5 59.2 51.7 54.2 64.5 50.0 73.0 33.7 119.3 69.2 52.7 71.8 55.4 56.4 27.0 28.2 31.3 35.4 36.2 22.0 28.2 29.7 33.2 17.3 23.7 25.0 14.6 42.7 38.1 25.4 37.3 30.2 10.5 13.3 7.2 14.5 12.9 15.7 9.8 11.5 11.5 9.5 15.7 12.2 10.8 3.2 7.7 26.1 19.0 12.0 18.8 19.4 15.9 13.4 17.8 10.3 12.9 4.3 19.0 27.6 27.1 16.3 8.8 33.4 17.6 28.6 14.6 14.5 11.6 12.0 15.7 10.9 45.4 31.2 14.8 14.1 22.4 18.0 10.8 8.2 8.2 12.7 17.0 18.5 33.1 17.3 14.2 15.5 8.4 8.6 7.8 11.6 7.2 30.0 21.3 14.4 16.5 26.2 31.9 25.3 20.9 11.3 15.5 22.9 15.3 19.1 20.5 19.4 13.1 10.5 10.2 43.0 33.8 17.6 13.8 16.6 17.8 25.3 15.7 24.5 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCD3 "PMP70, PXMP1, ZWS2" ENSG00000117528 "ATP binding cassette subfamily D member 3" P28288 1 94418389-94518666 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032026, HPA032027, CAB032516, CAB075749" Enhanced Enhanced Peroxisomes NA NA 12000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Peroxisomes "CAB032516: AB_2257637, CAB075749: AB_2665755, HPA032026: AB_2674117, HPA032027: AB_10602103" "unprognostic (1.41e-2)" "unprognostic (3.21e-1)" "prognostic favorable (1.16e-5)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (1.56e-1)" "unprognostic (1.94e-2)" "unprognostic (2.54e-2)" "unprognostic (5.10e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-1)" "unprognostic (9.12e-2)" "prognostic favorable (4.84e-5)" "unprognostic (5.45e-2)" "unprognostic (6.20e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" 16.8 18.7 19.8 16.2 23.2 25.1 32.8 22.7 24.3 22.4 22.6 44.6 44.5 14.7 21.2 26.7 16.7 26.8 26.0 18.7 21.8 59.4 126.6 23.3 13.3 22.1 21.2 10.1 28.6 29.6 13.3 14.4 22.7 21.5 40.2 26.3 17.5 27.0 23.5 35.5 46.1 17.7 23.7 11.0 43.5 16.3 21.4 47.5 27.5 29.8 21.2 22.9 16.2 27.3 81.5 37.6 37.8 36.1 28.3 31.0 55.8 41.4 32.0 46.8 51.5 117.5 25.0 49.8 52.1 52.8 50.0 58.2 43.7 53.7 64.9 40.1 36.9 56.7 52.3 102.5 27.5 51.2 17.0 26.2 29.6 54.2 20.8 30.2 29.0 47.0 25.8 29.2 48.6 11.4 86.4 26.8 43.7 61.7 50.7 48.0 78.4 19.4 45.6 122.2 28.5 46.7 71.5 75.2 55.7 28.4 27.7 41.8 28.9 34.5 49.5 61.3 55.9 16.5 16.5 48.4 27.1 25.6 16.4 0.4 3.8 2.9 4.2 4.3 4.0 1.8 3.8 4.9 5.9 1.8 4.5 4.4 0.9 5.9 3.8 1.5 4.6 3.3 19.8 23.2 22.7 24.3 18.7 21.8 22.1 21.2 22.7 23.7 21.4 27.3 16.9 35.3 48.8 64.3 10.2 23.3 16.2 32.8 14.8 27.5 43.7 21.1 39.1 58.6 43.2 42.3 22.9 25.0 12.3 72.1 23.5 22.8 9.0 37.5 16.8 16.4 39.7 8.4 32.7 44.5 12.0 18.3 37.8 30.6 27.9 19.1 18.2 108.9 11.0 33.7 47.5 37.5 26.4 21.9 7.4 8.2 13.7 15.0 16.0 40.3 15.1 78.4 11.3 67.3 96.5 37.5 33.0 24.5 15.4 20.4 75.7 72.3 49.8 26.3 19.7 19.0 17.7 14.5 23.2 21.0 34.0 15.3 15.4 16.7 39.5 32.5 ABLIM2 KIAA1808 ENSG00000163995 "Actin binding LIM protein family member 2" Q6H8Q1 4 7965310-8158832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 204.8;tongue: 73.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 93.2;Inhibitory neurons: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 13.8;SiHa: 5.9;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035808 Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Nucleoplasm "HPA035808: AB_10601962" "unprognostic (7.57e-2)" "unprognostic (3.24e-3)" "unprognostic (7.78e-2)" "unprognostic (3.33e-1)" "unprognostic (2.86e-2)" "unprognostic (6.09e-2)" "unprognostic (1.49e-2)" "unprognostic (5.54e-2)" "unprognostic (1.46e-1)" "unprognostic (5.01e-3)" "unprognostic (2.04e-2)" "unprognostic (3.61e-1)" "unprognostic (1.48e-1)" "unprognostic (4.32e-2)" "unprognostic (5.15e-2)" "unprognostic (1.45e-1)" "unprognostic (2.45e-2)" 7.3 4.0 2.7 1.6 11.0 0.1 5.1 0.0 9.9 2.5 0.0 2.3 0.5 1.2 0.7 13.1 1.8 1.3 7.1 2.7 10.4 7.0 0.9 3.3 1.0 1.4 0.0 0.6 3.4 1.3 6.8 0.6 1.1 1.5 1.7 5.0 5.4 0.5 204.8 6.9 1.6 1.9 0.0 20.5 1.4 1.0 1.4 1.7 3.0 73.5 2.2 1.9 4.1 0.0 1.1 0.0 0.2 1.6 0.4 0.1 0.4 0.0 0.0 0.1 0.0 0.0 1.5 3.1 0.3 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.4 0.0 1.3 0.0 0.7 0.0 0.0 0.1 1.1 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.7 2.1 0.1 0.0 1.2 2.9 0.9 0.2 1.0 0.7 0.2 0.0 13.8 1.0 5.9 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.4 20.7 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.6 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 2.7 11.0 0.0 9.9 2.7 10.4 1.4 0.0 1.1 0.0 1.4 0.0 4.4 0.0 1.1 9.4 0.5 2.5 0.1 0.1 0.6 6.4 0.4 0.3 4.7 1.5 0.3 3.7 0.0 0.0 0.6 7.9 0.0 3.5 2.2 5.2 0.7 3.5 10.7 0.0 93.2 4.3 0.6 0.9 2.6 0.2 2.5 0.5 0.7 0.4 0.1 11.8 67.6 3.8 0.0 0.6 0.7 5.1 0.0 0.3 0.0 2.8 0.0 3.1 0.0 16.1 17.6 3.5 5.1 3.8 0.1 0.3 14.3 0.6 1.7 3.2 6.6 7.0 3.5 0.2 2.0 2.0 6.3 0.0 0.7 4.0 5.8 0.3 ACAD8 ENSG00000151498 "Acyl-CoA dehydrogenase family member 8" Q9UKU7 11 134253548-134265855 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism, Transcription, Transcription regulation" "Activator, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 59.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040689, HPA043903" Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA040689: AB_2677080, HPA043903: AB_2678724" "unprognostic (5.00e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.62e-4)" "unprognostic (7.57e-3)" "unprognostic (9.83e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.53e-1)" "prognostic favorable (2.38e-4)" "unprognostic (4.10e-2)" "unprognostic (2.84e-1)" "unprognostic (7.81e-3)" "unprognostic (2.16e-1)" "prognostic favorable (6.42e-10)" "unprognostic (1.08e-1)" "unprognostic (1.17e-2)" "unprognostic (4.02e-2)" "unprognostic (1.03e-2)" 11.0 18.1 13.9 3.5 14.2 6.8 11.3 14.3 15.4 7.5 18.7 11.6 11.3 6.3 12.6 9.6 9.4 5.2 27.2 14.7 14.3 31.6 24.8 7.8 5.0 14.3 14.1 6.9 16.7 12.4 6.5 4.8 13.8 20.5 10.9 5.0 12.6 7.5 32.5 14.3 8.4 8.3 14.5 8.6 12.6 6.3 14.8 8.5 27.7 39.2 8.9 8.4 6.9 14.8 5.9 5.9 11.8 17.6 20.2 11.5 13.5 11.3 14.0 14.7 10.3 16.2 10.8 14.2 21.1 11.7 15.5 6.0 14.6 14.3 10.2 13.0 4.7 29.4 5.8 11.3 17.0 16.5 18.3 13.8 4.4 14.8 4.5 13.3 16.3 20.8 13.8 7.0 12.4 7.5 12.2 18.1 17.0 49.8 9.7 9.8 11.9 8.5 20.1 17.5 3.7 11.7 19.5 14.8 7.3 11.9 31.0 15.0 11.3 7.1 7.5 6.2 11.2 7.8 3.8 12.7 7.2 15.4 11.2 36.2 13.4 23.1 11.8 13.5 11.5 11.6 11.1 11.7 12.7 9.2 13.0 11.7 12.1 31.5 12.9 10.8 15.1 12.3 13.9 14.2 14.3 15.4 14.7 14.3 14.3 14.1 13.8 14.5 14.8 14.8 11.7 3.2 12.2 15.3 8.8 6.0 4.7 23.5 7.4 11.2 17.5 11.9 24.6 4.3 19.7 18.4 14.6 19.7 14.0 20.0 52.8 12.1 5.3 8.2 11.8 9.7 3.6 12.0 21.5 11.9 10.6 9.8 10.2 8.5 3.8 15.7 10.8 36.7 12.9 15.2 16.0 14.3 48.8 14.2 6.9 6.1 11.5 10.0 28.4 13.1 12.7 11.8 9.2 12.1 15.8 12.6 15.8 10.1 14.6 5.9 17.4 59.8 20.1 17.1 6.6 8.7 9.6 22.4 17.3 10.9 7.7 8.3 10.5 36.0 14.9 5.3 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACER2 "ALKCDase2, ASAH3L, FLJ41587" ENSG00000177076 "Alkaline ceramidase 2" Q5QJU3 9 19409009-19452505 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "stomach 1: 61.8;urinary bladder: 39.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.7;Gastric mucus-secreting cells: 21.9;Inhibitory neurons: 10.3;Microglial cells: 26.2;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 29.7;RT4: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.94e-1)" "unprognostic (2.29e-1)" "unprognostic (2.06e-1)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (2.03e-1)" "unprognostic (3.90e-1)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (2.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (8.46e-3)" 6.9 1.4 4.5 1.1 3.4 0.6 5.0 2.7 5.0 1.7 2.0 3.3 4.5 1.4 4.2 2.2 3.7 1.7 2.9 4.4 3.1 1.9 2.4 2.2 1.0 3.2 3.1 1.0 6.8 2.5 1.1 9.7 4.3 3.7 4.3 3.8 1.9 4.5 1.2 5.9 2.7 1.3 2.8 1.4 61.8 1.9 5.9 2.4 2.5 1.0 1.3 39.2 1.7 3.7 1.2 2.0 3.9 2.0 6.2 0.5 29.7 2.1 1.4 0.7 1.0 0.6 1.9 1.3 0.7 0.3 0.4 4.5 0.8 5.8 1.5 2.4 1.1 2.1 1.6 3.0 1.3 0.5 2.0 1.8 5.6 2.2 2.4 0.6 6.2 2.1 3.1 3.8 2.0 1.7 3.6 1.8 3.1 11.1 0.9 3.2 1.0 0.7 0.6 73.6 6.9 1.8 0.4 2.2 0.5 9.3 2.7 2.5 3.1 0.5 1.5 0.6 0.9 1.4 1.7 1.4 0.6 1.5 1.3 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.5 3.4 2.7 5.0 4.4 3.1 3.2 3.1 4.3 2.8 5.9 3.7 3.2 0.0 0.0 1.0 0.7 0.3 0.4 0.1 0.6 1.0 0.3 0.4 0.1 0.0 0.1 0.0 2.1 0.5 0.4 0.0 0.0 0.1 2.6 0.3 0.2 0.8 0.0 0.8 19.7 0.0 0.6 0.3 21.9 0.4 0.0 0.0 1.4 0.0 0.1 0.0 10.3 0.0 0.0 0.0 0.0 4.0 0.3 0.2 0.0 26.2 0.0 0.6 0.0 5.5 7.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.1 0.6 0.0 0.6 0.4 0.4 0.4 0.8 0.0 4.0 0.3 0.0 0.0 1.1 ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 335.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" 10.9 3.0 6.2 4.8 8.5 3.0 5.4 8.5 9.3 5.2 4.0 6.4 6.2 4.2 3.1 6.9 4.1 3.2 3.4 6.3 8.5 4.7 2.5 8.0 4.2 8.6 7.1 2.3 2.9 3.5 2.1 6.2 9.5 4.1 5.5 2.3 4.2 2.3 1.6 2.9 4.6 3.9 8.4 5.6 3.4 6.0 7.3 2.2 3.3 1.2 3.8 4.5 4.4 12.0 7.3 7.7 6.4 7.6 29.2 14.0 5.7 11.2 10.7 8.2 9.2 6.0 7.3 6.4 8.4 8.0 10.3 12.9 10.9 10.6 10.0 8.6 4.3 9.0 4.8 3.6 8.1 9.3 15.0 6.3 5.0 11.8 10.9 4.8 16.8 5.8 6.1 4.2 9.9 5.9 0.7 6.2 3.6 19.3 8.8 4.3 22.8 5.0 6.8 7.2 2.2 5.5 13.9 12.6 3.5 4.9 10.7 5.1 22.2 8.2 6.4 23.3 8.3 3.1 7.1 8.6 5.1 4.7 8.9 0.1 4.3 2.5 0.7 3.1 0.8 1.2 0.5 0.9 4.6 0.4 0.3 0.4 0.9 0.2 2.4 1.5 1.2 1.6 6.2 8.5 8.5 9.3 6.3 8.5 8.6 7.1 9.5 8.4 7.3 12.0 32.4 41.7 35.0 52.9 11.5 31.9 21.4 17.0 33.0 18.8 11.3 11.0 7.5 11.5 27.6 9.2 10.4 13.6 11.3 54.6 7.9 15.5 66.8 6.3 29.0 29.4 2.4 13.5 65.0 17.6 7.5 17.0 26.0 11.5 83.5 30.9 27.8 10.0 44.4 43.7 71.9 30.5 18.3 64.1 67.1 31.7 20.2 64.0 17.8 61.8 40.0 11.3 12.3 159.3 335.1 18.6 37.9 25.9 8.6 15.6 20.0 15.3 12.3 10.0 6.6 17.0 21.0 69.8 25.9 26.3 16.8 26.8 15.2 7.2 20.1 24.1 ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 320.5;breast: 278.2" "Group enriched" "Detected in many" 5 "Adipocytes: 383.6;Endothelial cells: 523.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 44.4;HSkMC: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" 320.5 13.4 17.7 42.0 21.8 14.5 278.2 34.6 25.5 141.7 21.6 67.0 15.3 125.0 21.5 63.6 121.2 59.2 42.2 18.4 18.6 34.5 1.8 146.8 49.3 21.4 17.7 21.4 15.8 9.7 11.6 10.4 23.2 72.9 19.4 23.7 61.3 24.5 51.7 85.3 60.9 107.7 24.9 82.1 57.0 8.6 17.0 33.2 47.7 30.2 40.8 112.4 113.1 22.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 44.4 0.0 0.0 5.5 0.0 0.0 30.7 0.0 0.0 3.9 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 21.8 34.6 25.5 18.4 18.6 21.4 17.7 23.2 24.9 17.0 22.0 383.6 6.4 10.8 1.6 1.0 0.0 1.7 0.0 2.8 78.4 3.6 3.7 15.1 0.0 1.8 0.0 2.1 0.4 0.8 0.0 0.0 0.0 2.2 0.4 1.0 523.8 0.0 81.3 3.6 9.8 0.2 18.9 0.0 0.4 5.1 0.0 7.5 0.0 1.1 6.7 3.2 0.0 0.0 0.8 0.0 3.7 1.2 2.2 0.0 1.0 0.0 5.9 0.0 0.5 0.3 0.0 0.0 0.4 0.1 2.2 0.0 0.1 0.7 3.7 0.0 3.9 4.5 0.2 0.5 4.0 0.0 0.1 1.1 0.1 0.0 2.3 ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368298 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3643.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Hofbauer cells: 4.7;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 139.7" "Lineage enhanced" "Detected in many" "granulocytes: 139.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 17.7;OE19: 22.3;RPMI-8226: 58.0;U-698: 17.2;U-87 MG: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" NA NA 460000 480000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" 3.1 5.4 0.9 7.3 1.3 17.5 3.4 0.9 0.9 6.3 1.2 3.6 3.1 1.4 17.2 47.7 2.2 1.5 0.6 1.2 1.5 28.9 1.4 4.5 1.9 1.5 1.3 1.1 2.7 3.9 0.5 10.8 1.5 3643.7 6.5 0.4 10.6 0.8 0.2 27.0 3.4 1.8 1.0 1.8 3.2 2.4 1.0 1.0 2.4 0.2 6.5 1.8 12.1 1.7 0.5 0.1 0.0 0.0 0.2 0.9 11.7 0.3 17.7 0.1 0.0 0.4 0.4 10.6 0.8 0.0 0.1 4.8 0.0 0.1 0.0 0.1 0.5 2.0 0.4 0.2 0.2 7.3 0.1 1.1 1.6 0.1 0.0 0.2 0.0 0.0 0.1 2.7 0.2 0.1 0.0 13.5 0.7 22.3 2.1 0.1 0.0 58.0 5.0 6.5 0.0 4.1 0.1 2.0 0.6 1.7 0.3 6.5 0.0 0.1 0.1 2.5 0.1 0.8 0.4 17.2 14.9 12.7 0.2 0.1 30.2 139.7 0.2 26.9 0.2 0.7 0.0 0.0 35.3 0.0 0.0 0.0 26.4 2.6 25.8 2.4 0.0 10.1 0.9 1.3 0.9 0.9 1.2 1.5 1.5 1.3 1.5 1.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374018-112428380 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 217.8;intestine: 418.0;liver: 165.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.9;Endometrial ciliated cells: 159.9;Glandular and luminal cells: 292.3;Proximal enterocytes: 462.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 138.8;RT4: 143.3;U-937: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" 23.8 4.2 13.1 29.0 12.6 16.2 21.3 13.0 15.5 51.4 10.4 111.7 358.9 30.3 217.8 7.9 45.0 21.5 9.4 12.1 13.4 9.0 165.5 35.6 28.0 14.4 13.1 17.0 5.5 2.2 2.6 8.6 14.9 12.3 116.6 1.5 5.5 20.3 3.9 3.4 418.0 15.5 14.0 25.7 44.2 9.6 15.3 16.4 7.2 8.8 28.0 76.3 7.6 13.2 38.6 0.9 0.7 0.1 2.5 0.4 3.3 1.1 7.3 0.3 0.6 34.8 138.8 46.7 8.4 1.9 6.8 0.3 0.0 0.2 0.8 39.4 0.0 36.5 1.3 60.9 8.8 57.3 59.2 5.9 0.0 0.8 0.0 2.7 2.8 0.0 0.1 20.6 0.1 0.0 0.1 26.3 0.1 32.2 1.3 12.9 0.2 28.6 3.8 143.3 0.1 0.9 55.8 21.0 0.1 0.1 0.1 31.7 40.5 0.5 0.4 2.2 2.5 14.8 0.1 22.6 1.2 70.5 0.1 27.4 15.1 27.5 25.2 27.9 24.9 16.3 20.4 27.8 31.1 13.1 13.8 21.4 3.9 26.1 27.7 9.8 41.5 21.1 13.1 12.6 13.0 15.5 12.1 13.4 14.4 13.1 14.9 14.0 15.3 13.2 23.4 12.8 51.3 0.0 20.1 3.8 10.3 10.7 8.6 0.1 7.0 4.6 1.7 12.8 23.6 0.0 4.2 1.8 10.5 164.9 0.0 13.3 92.6 159.9 37.6 24.7 40.8 10.7 1.3 6.4 2.6 5.7 41.8 292.3 17.2 0.5 16.1 88.6 18.9 0.0 1.1 79.0 0.0 22.4 57.8 42.6 15.8 24.9 3.6 17.8 11.5 0.1 16.5 1.0 1.0 48.0 122.4 12.0 20.3 7.1 462.5 0.2 8.2 1.2 0.0 0.8 3.3 4.0 1.9 3.3 1.7 0.7 24.0 6.4 103.3 50.0 ACSL6 "ACS2, FACL6, KIAA0837, LACS2, LACS5" ENSG00000164398 "Acyl-CoA synthetase long chain family member 6" Q9UKU0 5 131949973-132012243 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.6;brain: 32.0;retina: 45.8;testis: 20.7" "Cell type enhanced" "Detected in many" "Astrocytes: 229.2;Cone photoreceptor cells: 229.4;Erythroid cells: 110.5;Inhibitory neurons: 110.6;Rod photoreceptor cells: 130.0" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.8;glioma: 1.9;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 5 "T-cells: 1.6" "Group enriched" "Detected in some" 5 "SCLC-21H: 7.6;U-937: 6.2" HPA040470 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA040470: AB_10794033" "unprognostic (1.99e-2)" "unprognostic (1.94e-1)" "unprognostic (3.55e-3)" "unprognostic (5.89e-2)" "unprognostic (6.97e-2)" "unprognostic (1.92e-2)" "unprognostic (8.38e-3)" "unprognostic (5.84e-2)" "unprognostic (8.69e-2)" "unprognostic (7.57e-2)" "unprognostic (9.28e-4)" "unprognostic (8.69e-2)" "unprognostic (3.22e-2)" "unprognostic (6.24e-3)" "unprognostic (1.79e-1)" "unprognostic (6.44e-3)" "unprognostic (1.70e-1)" 0.2 4.2 14.8 1.4 18.3 22.6 0.2 26.3 32.0 0.1 1.2 0.5 4.7 0.1 0.5 0.3 0.2 0.3 1.4 18.6 12.8 1.9 2.0 0.3 2.4 22.2 18.2 0.0 1.1 11.3 4.2 0.6 18.9 0.3 0.3 45.8 0.3 18.0 2.3 0.1 2.4 0.1 13.8 1.1 0.6 20.7 25.0 0.6 0.4 1.4 1.0 0.2 0.1 14.3 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.1 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.2 6.2 0.3 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.7 1.6 0.0 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 0.3 14.8 18.3 26.3 32.0 18.6 12.8 22.2 18.2 18.9 13.8 25.0 14.3 0.6 25.6 29.2 229.2 1.4 1.9 1.5 0.0 2.2 65.2 2.1 0.4 0.0 1.5 16.1 1.8 229.4 0.3 3.3 0.6 7.9 0.6 43.7 0.3 0.1 3.9 2.4 110.5 70.6 0.2 0.1 4.2 0.0 0.2 10.1 0.2 1.8 8.4 0.1 21.9 110.6 1.8 0.0 1.0 15.9 7.9 0.3 6.4 0.0 15.9 0.9 24.5 0.0 41.7 9.8 0.3 1.6 1.9 0.8 1.1 1.8 0.4 8.1 130.0 0.0 2.3 1.1 45.3 1.7 0.1 1.3 0.3 15.3 0.1 0.4 1.3 ACTB ENSG00000075624 "Actin beta" P60709 7 5526409-5563902 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 22882.9;Pancreatic endocrine cells: 14370.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002621, HPA041264, HPA041271" Supported NA NA 5800000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "CAB002621: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (1.66e-1)" "unprognostic (1.15e-1)" "unprognostic (4.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (9.80e-3)" "unprognostic (1.57e-3)" "unprognostic (1.73e-1)" "unprognostic (5.99e-2)" "unprognostic (3.33e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (3.78e-5)" "unprognostic (2.68e-2)" "unprognostic (3.20e-1)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" 2558.1 1235.8 2143.2 4250.8 2321.0 3598.4 2009.8 2400.1 2776.1 2274.6 2183.3 6581.2 1659.0 5033.9 1630.3 2928.9 2943.6 1772.1 817.6 2355.6 2315.8 1313.6 1759.9 2876.0 4394.2 2654.8 2338.9 1711.5 761.9 838.5 731.4 1817.2 2569.2 2027.1 2338.4 488.2 1470.2 2943.2 465.1 1541.7 2825.9 5736.8 2457.9 3009.5 2869.7 558.3 2483.4 3278.4 1317.9 524.0 4602.3 3720.8 2223.5 3045.4 7791.1 5198.8 5604.1 4658.2 2321.1 3120.3 6654.3 6049.6 4853.2 6209.7 4619.4 8249.5 4361.9 4522.7 4557.0 9445.4 4904.8 4820.3 3279.5 9453.9 4507.4 5324.6 1668.7 3974.3 4579.6 4520.6 3538.8 4733.2 9853.8 4098.5 2786.7 6863.0 1738.0 4128.6 5073.2 3561.3 2189.7 3513.0 6603.4 7531.9 4055.1 13162.1 6813.7 2468.5 3490.8 5658.6 3351.4 3419.7 5904.6 3175.8 1633.1 2746.9 5754.7 5822.1 2400.3 5088.3 5859.7 5314.8 7975.3 10437.4 7019.9 7000.1 8802.8 1902.3 2442.5 5082.1 5772.0 6622.6 12412.7 14674.1 18104.2 29636.6 10647.1 19648.6 8327.7 5139.6 7639.4 9512.9 19292.5 4844.1 5592.0 7894.3 18040.6 6233.1 22870.8 7122.2 11463.2 37406.8 2143.2 2321.0 2400.1 2776.1 2355.6 2315.8 2654.8 2338.9 2569.2 2457.9 2483.4 3045.4 2775.4 1150.6 680.4 142.4 4118.9 5737.0 9776.6 5792.0 3110.2 146.7 1564.0 2047.2 145.3 1080.9 2763.3 2144.5 85.5 3647.7 3989.3 3419.3 2277.4 6508.8 101.3 1422.1 2344.0 2768.4 1451.5 3170.9 129.3 6365.4 12480.2 2958.5 3136.1 2041.6 1539.9 2372.0 2163.5 2590.6 13977.7 269.2 101.3 2006.7 3694.5 7392.0 11420.0 199.7 1766.7 8486.4 2995.4 259.5 22882.9 1654.4 5237.9 116.1 302.2 14370.0 2899.8 2680.3 3040.4 4764.9 4968.2 2149.2 1453.8 146.7 3287.0 1398.2 5423.9 133.8 381.9 4376.1 4722.2 3257.7 5961.7 1688.9 1966.6 6941.4 ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 47.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 1021.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.1;HSkMC: 11.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA035817, HPA035818" Approved Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA035817: AB_10671938, HPA035818: AB_2674801" "unprognostic (2.35e-1)" "unprognostic (9.39e-2)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "unprognostic (3.29e-1)" "unprognostic (1.24e-1)" "unprognostic (7.31e-4)" "unprognostic (2.64e-1)" "unprognostic (9.16e-2)" "unprognostic (4.41e-2)" "unprognostic (8.03e-2)" "unprognostic (8.49e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-3)" "unprognostic (2.22e-1)" 1.6 0.9 1.7 0.7 2.1 0.4 1.1 2.6 4.5 1.4 2.0 0.9 1.1 1.1 0.8 1.0 2.0 0.9 1.2 2.2 2.0 2.4 2.7 1.1 0.8 2.1 3.5 1.6 0.6 1.2 1.3 1.0 2.2 1.2 0.8 0.8 0.6 1.9 0.7 0.4 0.8 1.6 1.8 0.4 1.2 47.5 2.5 0.8 1.5 0.7 0.9 1.7 0.7 2.6 4.0 2.5 0.2 1.1 18.1 5.5 0.0 4.7 3.0 3.1 2.6 0.0 5.2 0.0 6.5 5.9 2.0 2.5 1.5 2.5 3.3 2.9 1.7 9.3 1.9 0.5 3.0 1.1 0.9 11.8 0.6 3.8 0.7 2.0 5.8 0.9 0.0 0.0 5.7 2.0 0.2 0.1 4.5 3.5 5.3 0.6 0.0 0.1 3.3 1.0 3.1 2.1 5.9 1.4 0.1 0.6 2.5 4.1 2.4 0.0 0.0 2.5 0.0 0.4 0.2 0.2 1.1 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.7 2.1 2.6 4.5 2.2 2.0 2.1 3.5 2.2 1.8 2.5 2.6 0.9 0.0 1.5 0.3 0.1 0.4 1.3 1.6 1.2 1.6 0.4 0.4 0.7 0.0 2.0 0.0 2.1 1.7 0.1 0.2 1.9 2.3 1021.8 1.1 0.6 1.8 0.0 0.4 0.2 2.1 1.3 1.7 0.5 0.9 1.3 1.3 2.2 2.1 1.5 3.3 0.2 1.3 0.0 0.8 0.7 161.0 9.6 2.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 2.1 0.1 5.7 0.2 0.7 0.5 2.8 2.1 1.3 13.1 1.1 1.4 24.6 4.6 1.2 0.0 0.8 1.3 3.8 1.2 0.4 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.6;lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "dendritic cells: 54.7;Extravillous trophoblasts: 96.4;Langerhans cells: 124.9;monocytes: 81.3;NK-cells: 82.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 21.2" "Group enriched" "Detected in many" 5 "basophil: 107.4;eosinophil: 259.0;neutrophil: 139.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.0" "Cell line enhanced" "Detected in many" "A-431: 60.0;BEWO: 81.8;CAPAN-2: 70.4;HaCaT: 69.8;HDLM-2: 45.9;U-87 MG: 34.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA064637: AB_2685306" "unprognostic (8.24e-2)" "unprognostic (6.07e-3)" "unprognostic (1.27e-3)" "unprognostic (5.18e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-3)" "unprognostic (3.37e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (3.99e-10)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.32e-2)" 5.6 2.4 2.1 22.1 2.3 68.6 2.7 1.4 21.2 4.2 1.7 3.6 5.8 2.2 2.1 3.5 6.0 5.1 2.5 1.8 1.8 4.7 8.4 21.5 11.6 3.2 1.9 3.0 4.3 0.3 3.6 3.1 4.4 4.5 1.6 1.5 4.2 1.1 1.2 3.2 11.3 2.1 1.6 48.5 11.5 2.6 5.9 4.0 3.8 1.7 8.2 11.9 3.2 3.4 60.0 1.7 0.5 0.9 0.4 0.1 81.8 0.7 1.4 0.3 0.4 4.6 70.4 1.0 1.7 0.1 0.5 69.8 0.2 11.9 0.1 45.9 1.0 0.8 0.5 0.0 0.7 3.6 15.9 0.2 1.1 0.6 1.0 3.7 0.1 0.5 3.2 2.4 0.0 4.8 0.2 20.2 0.3 7.1 1.7 0.4 0.7 6.6 0.8 1.4 0.1 0.8 0.4 0.2 1.0 1.1 1.0 2.0 1.7 0.0 1.5 0.6 1.0 3.4 2.2 0.6 34.5 2.0 0.2 107.4 24.8 259.0 22.2 9.2 15.9 10.2 14.8 21.4 37.2 5.6 5.6 8.2 139.4 24.7 9.4 0.7 16.9 25.2 2.1 2.3 1.4 21.2 1.8 1.8 3.2 1.9 4.4 1.6 5.9 3.4 1.3 3.2 10.5 3.3 23.2 7.8 6.6 14.3 0.0 4.3 2.2 1.8 2.4 2.8 9.5 0.0 8.4 7.7 54.7 0.3 1.9 3.1 1.0 1.5 0.9 1.7 0.0 5.7 3.5 2.7 96.4 2.4 6.1 2.1 12.6 1.1 2.5 2.4 23.3 0.0 3.0 0.6 2.0 8.8 124.9 0.4 0.9 33.9 7.2 0.0 81.3 0.2 82.4 2.0 2.9 39.1 0.1 0.0 20.7 11.0 0.3 0.5 10.0 5.1 0.0 0.8 1.0 1.5 0.8 0.6 6.5 20.0 39.4 0.2 0.5 42.5 ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 25.2;Fibroblasts: 22.9;Leydig cells: 22.1;Microglial cells: 73.1;Sertoli cells: 52.6;Theca cells: 55.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 47.4;hTERT-RPE1: 88.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" 9.0 5.2 0.9 1.6 0.7 0.0 7.8 0.5 0.4 2.7 1.7 2.5 0.5 3.8 0.5 0.9 3.2 4.0 1.6 0.2 0.4 1.3 1.4 5.6 0.9 1.2 0.9 2.7 0.6 0.5 0.6 3.9 1.0 1.3 1.0 0.7 0.9 1.4 0.8 1.5 1.1 6.5 1.5 0.5 1.2 2.0 1.3 0.3 1.9 0.7 0.6 2.2 2.0 3.3 28.7 0.9 25.5 0.0 35.9 17.2 0.0 13.3 33.1 16.8 19.5 0.0 0.0 0.0 0.0 9.0 29.1 0.8 0.7 16.7 24.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 13.8 0.0 47.4 12.2 88.0 0.0 0.0 0.0 0.1 26.6 0.0 0.0 0.0 5.0 0.0 0.0 0.0 29.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.0 0.0 28.0 36.2 0.3 7.9 4.4 3.5 0.0 23.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 0.4 0.2 0.4 1.2 0.9 1.0 1.5 1.3 3.3 6.4 0.0 0.0 1.3 0.5 0.8 0.0 0.0 0.0 0.1 1.5 2.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.9 1.2 25.2 2.1 0.0 0.0 3.0 0.2 0.4 22.9 0.0 0.6 0.0 3.3 11.4 0.2 0.6 0.0 6.2 0.0 0.0 0.3 2.1 3.0 22.1 0.2 7.2 73.1 0.0 5.3 0.0 0.5 7.8 0.1 0.0 17.7 0.0 0.1 0.0 2.4 0.7 0.2 52.6 1.7 19.1 0.4 4.7 0.1 0.9 0.8 0.3 55.4 0.0 0.1 ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.6;Excitatory neurons: 50.2;Leydig cells: 19.9;Rod photoreceptor cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;AN3-CA: 7.8;HEL: 14.1;K-562: 12.3;SH-SY5Y: 7.0;U-2 OS: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" 2.3 0.8 0.5 1.0 2.5 0.8 3.2 0.0 1.5 0.4 0.1 0.3 0.1 1.9 1.7 0.2 2.9 0.6 0.9 1.5 0.6 0.9 0.2 1.1 0.8 0.0 0.2 2.0 0.3 2.7 0.2 0.7 0.1 0.7 0.3 8.4 0.4 1.1 0.2 0.4 0.2 1.7 0.0 0.7 0.5 1.9 0.1 0.6 1.2 0.3 0.3 1.3 0.4 0.4 0.0 0.0 13.2 7.8 0.1 0.3 0.1 0.7 2.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.8 0.0 1.8 0.0 1.8 14.1 0.9 0.0 0.2 0.0 0.0 1.7 0.1 0.6 0.1 3.3 0.0 0.0 12.3 0.0 0.0 0.0 1.3 0.0 2.2 0.0 4.0 0.0 2.6 0.0 4.6 0.0 0.5 7.0 0.0 0.6 0.2 1.4 0.1 0.2 0.1 5.6 8.5 0.0 0.7 0.0 0.0 0.0 1.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.5 0.0 1.5 1.5 0.6 0.0 0.2 0.1 0.0 0.1 0.4 1.8 0.0 3.4 7.5 0.0 0.5 0.9 0.0 0.0 0.9 0.8 3.2 1.2 1.5 1.3 1.8 14.6 0.0 0.0 0.0 0.0 0.0 4.1 2.2 5.1 3.7 0.0 2.5 50.2 0.0 0.3 3.3 0.0 0.7 1.3 1.9 3.9 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.7 1.9 19.9 0.3 0.0 1.0 0.0 1.8 0.0 7.1 1.3 0.0 0.0 4.5 0.0 1.1 0.0 0.3 0.5 12.9 0.0 0.3 1.2 1.2 0.8 0.3 0.0 0.0 0.0 2.8 0.0 0.1 ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 9.8;Cardiomyocytes: 9.6;Leydig cells: 19.3;Peritubular cells: 18.0;Proximal enterocytes: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" 1.8 1.5 1.7 0.7 2.2 0.3 2.2 2.3 2.0 33.0 8.3 3.2 9.8 19.8 5.0 15.1 9.5 0.5 20.7 1.8 0.4 1.5 4.2 1.4 0.6 0.8 1.0 1.3 1.0 1.4 2.6 4.2 0.6 4.5 1.1 0.9 3.9 3.3 15.1 2.1 8.4 12.5 0.2 0.8 1.4 3.6 1.6 0.2 1.5 5.9 1.5 3.8 22.5 1.4 8.1 3.5 0.1 0.1 4.1 3.0 3.8 14.7 9.8 5.6 8.1 20.7 4.0 0.0 3.6 12.3 1.6 6.7 3.5 4.2 4.2 7.9 0.4 1.7 11.0 3.8 4.6 0.2 10.2 1.8 4.6 1.3 3.5 7.4 0.0 2.5 5.0 9.8 0.6 7.5 0.4 0.4 0.1 2.3 1.8 0.2 0.8 2.1 4.5 0.0 0.1 0.3 3.5 0.4 4.4 1.9 9.2 3.0 0.9 0.0 5.4 10.9 0.6 6.2 4.2 1.0 0.1 0.8 2.4 0.2 0.0 0.4 1.4 0.5 0.9 0.0 1.6 1.1 0.0 0.0 2.0 1.3 0.1 0.0 0.9 0.0 0.5 0.5 1.7 2.2 2.3 2.0 1.8 0.4 0.8 1.0 0.6 0.2 1.6 1.4 0.2 0.0 1.1 3.6 0.3 0.4 2.4 9.8 6.2 0.3 1.9 0.8 9.6 0.0 3.4 0.0 0.0 0.8 0.7 0.6 0.0 0.6 0.6 0.3 4.5 0.4 0.0 0.0 0.1 1.7 2.1 5.8 1.1 0.4 0.0 0.5 0.0 1.8 0.3 0.0 0.1 1.8 4.1 0.0 0.4 2.6 19.3 0.4 1.8 1.0 0.0 3.7 0.0 0.0 0.1 7.0 1.5 18.0 1.8 2.7 12.5 0.5 1.3 2.1 0.0 0.9 3.3 0.6 1.9 8.4 0.4 0.7 1.2 0.3 1.6 3.5 ADCY2 "AC2, HBAC2, KIAA1060" ENSG00000078295 "Adenylate cyclase 2" Q08462 5 7396138-7830081 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 50.8;skeletal muscle: 68.3;tongue: 30.8" "Group enriched" "Detected in many" 5 "Astrocytes: 647.1;Excitatory neurons: 406.6;Horizontal cells: 201.9;Inhibitory neurons: 423.9;Oligodendrocyte precursor cells: 181.5" "Cancer enhanced" "Detected in some" "glioma: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 5.6;NTERA-2: 4.3;SK-MEL-30: 4.6;SuSa: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031482, HPA038015, HPA038483" Approved NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB031482: AB_630838, HPA038015: AB_10673653, HPA038483: AB_10675799" "unprognostic (6.48e-2)" "unprognostic (2.60e-2)" "unprognostic (1.49e-1)" "unprognostic (5.65e-2)" "unprognostic (3.77e-1)" "unprognostic (4.03e-4)" "unprognostic (1.94e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (7.68e-2)" "unprognostic (1.09e-5)" "unprognostic (1.05e-1)" "unprognostic (7.33e-3)" "unprognostic (4.90e-2)" "unprognostic (3.92e-3)" 1.4 2.2 32.3 0.3 39.1 0.1 1.8 25.9 39.9 4.5 8.0 3.2 0.9 3.2 0.6 3.0 3.0 1.1 0.4 38.2 37.6 0.2 0.0 0.3 0.0 43.4 44.1 3.9 0.8 0.4 6.3 0.8 34.1 5.2 0.5 7.0 1.8 3.9 68.3 5.4 1.1 3.3 50.8 0.2 1.6 2.7 33.8 0.2 0.4 30.8 0.1 1.9 3.1 37.8 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 3.8 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 32.3 39.1 25.9 39.9 38.2 37.6 43.4 44.1 34.1 50.8 33.8 37.8 0.3 3.2 2.7 647.1 0.1 5.9 0.7 0.1 0.0 26.8 1.5 1.5 2.2 1.5 2.6 0.0 68.8 0.6 0.2 0.2 0.0 0.6 3.2 0.2 1.6 1.3 12.6 0.0 406.6 0.5 0.3 3.5 0.0 0.2 1.3 3.2 0.4 0.2 0.2 201.9 423.9 1.2 0.0 0.0 5.0 4.9 4.4 0.9 40.9 20.6 0.0 2.0 0.0 181.5 10.6 3.6 7.6 1.9 0.0 8.0 0.2 0.2 5.3 4.9 0.0 11.9 0.9 1.2 1.7 0.0 4.7 0.8 0.7 0.3 0.4 1.4 ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;Rod photoreceptor cells: 624.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" 104.4 70.0 96.4 60.7 119.7 65.9 89.1 86.7 117.7 96.5 46.4 127.9 65.5 121.4 57.9 71.9 96.3 69.0 111.2 99.2 90.9 74.1 53.7 93.5 65.3 91.5 100.4 129.5 56.4 67.5 70.1 66.0 92.3 86.1 62.7 269.1 61.9 107.3 166.3 69.4 92.3 110.2 76.0 88.9 84.3 53.2 113.2 76.0 71.7 115.0 62.1 115.3 82.9 116.2 74.7 61.2 142.0 73.8 205.8 152.6 53.2 123.2 146.9 125.6 105.3 90.5 91.8 38.7 63.0 212.3 146.6 46.6 107.5 103.4 104.3 49.9 49.4 109.5 50.4 87.9 100.4 65.8 74.7 151.6 95.2 110.4 44.0 130.1 158.5 71.9 116.0 90.8 145.1 43.7 203.7 91.6 80.0 67.9 85.7 89.1 78.6 45.7 91.2 162.2 84.8 110.0 88.9 35.8 76.9 107.0 84.2 61.7 193.4 102.1 52.4 84.7 103.0 72.5 63.3 48.9 98.2 80.4 100.9 20.1 7.6 35.5 19.1 7.3 17.6 23.8 10.6 16.3 12.0 31.2 9.8 11.8 10.5 27.2 11.4 25.4 14.8 16.0 96.4 119.7 86.7 117.7 99.2 90.9 91.5 100.4 92.3 76.0 113.2 116.2 89.3 70.5 45.4 141.3 66.5 26.9 29.8 33.0 27.9 99.5 41.2 41.5 78.0 40.0 46.3 60.7 402.4 35.5 84.0 51.3 15.6 37.3 48.5 43.9 61.2 89.4 57.7 57.9 85.7 45.8 32.5 72.9 39.8 58.1 37.3 53.0 84.3 41.8 41.8 111.0 83.2 39.3 28.5 51.6 42.2 35.9 77.6 47.4 35.6 72.1 58.3 233.8 120.5 68.9 178.6 53.2 39.4 121.9 49.7 35.8 48.6 44.6 40.4 624.3 98.6 58.4 73.1 45.3 33.2 30.5 36.7 36.5 55.6 80.7 45.1 33.0 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61201258-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3" "Group enriched" "Detected in many" 11 "Astrocytes: 584.1;Excitatory neurons: 696.1;Inhibitory neurons: 737.4;Oligodendrocyte precursor cells: 1300.8;Oligodendrocytes: 592.1" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 41.8;EFO-21: 10.8;HEK 293: 6.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" 7.1 6.2 25.1 1.1 25.7 0.0 2.5 14.0 30.7 5.5 0.0 4.0 2.5 3.9 1.8 1.0 2.4 1.6 2.6 30.4 25.0 1.6 0.4 2.6 0.4 15.3 24.6 1.1 0.3 6.7 0.9 1.2 15.9 1.3 3.9 10.0 0.6 4.2 0.7 3.0 3.6 3.0 12.5 0.3 3.2 4.1 32.3 0.4 0.7 0.3 0.1 1.6 3.4 15.7 0.0 0.1 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 3.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 1.0 0.0 4.0 0.5 0.1 0.1 0.0 4.8 0.2 0.0 6.3 0.3 0.0 0.0 0.0 7.6 0.1 3.2 0.0 0.2 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 25.7 14.0 30.7 30.4 25.0 15.3 24.6 15.9 12.5 32.3 15.7 0.4 0.0 0.0 584.1 0.0 0.0 0.0 0.0 0.6 12.4 4.9 1.8 3.3 0.0 0.0 0.0 4.2 1.0 0.0 0.0 9.8 0.0 46.4 1.3 17.7 1.9 0.0 0.0 696.1 0.0 1.3 3.3 0.0 0.4 0.0 0.4 2.5 0.2 0.1 1.7 737.4 0.0 0.0 0.0 0.0 33.2 0.0 0.5 0.0 70.3 0.0 31.3 0.0 1300.8 592.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 2.4 6.6 0.3 18.5 0.9 3.5 1.2 0.0 2.2 0.2 0.1 0.0 0.1 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 638.7;intestine: 1224.0;stomach 1: 1402.3" "Cell type enhanced" "Detected in many" "Club cells: 1515.8;Distal enterocytes: 1026.4;Gastric mucus-secreting cells: 2605.5;Intestinal goblet cells: 3710.4;Paneth cells: 1101.6;Undifferentiated cells: 1543.1;Urothelial cells: 1017.8" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 15 "OE19: 20084.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 38000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" 2.1 0.7 0.0 66.6 0.0 0.0 72.3 0.2 0.5 638.7 0.0 768.1 486.0 14.1 389.1 16.2 306.4 275.8 0.2 0.1 0.0 11.2 0.9 50.7 0.6 0.0 0.1 0.3 22.1 0.1 31.4 1.6 0.0 227.3 1224.0 0.0 475.3 181.0 0.2 2.5 379.2 45.2 0.0 0.9 1402.3 0.9 0.0 1.7 7.4 0.1 7.2 160.8 4.0 0.1 0.3 265.5 0.0 0.3 0.0 0.1 2.6 0.0 0.0 0.0 0.0 43.5 39.7 0.0 0.2 0.0 6.6 25.2 0.0 34.5 0.2 0.0 0.0 0.0 0.9 3.8 0.0 0.0 1.0 0.0 88.5 0.0 11.4 0.4 0.4 0.3 0.0 0.0 0.2 44.7 1.3 1.8 0.8 20084.0 154.2 1.0 0.0 5.2 631.3 371.6 1.7 2.1 0.0 98.8 0.0 1.0 1319.9 0.0 0.0 0.7 1.2 0.9 0.2 1.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 51.3 293.1 0.0 19.0 2.8 127.1 539.8 0.6 0.0 169.3 137.4 0.2 268.8 1515.8 80.9 0.0 6.0 0.4 1026.4 0.0 74.1 4.6 301.9 33.9 4.8 522.1 0.0 0.1 835.1 4.5 6.0 2605.5 365.3 43.9 0.0 0.0 1.7 240.8 0.0 0.1 3710.4 386.6 0.8 0.3 0.4 0.3 6.5 3.6 0.0 1.0 0.0 0.0 0.0 0.0 303.1 1101.6 0.0 2.6 426.9 517.9 0.2 781.0 0.0 0.0 0.0 76.9 0.4 0.2 5.3 2.8 3.3 13.1 0.0 1543.1 1017.8 AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 225.2;intestine: 237.6;lung: 152.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 861.1;Intestinal goblet cells: 701.9;Paneth cells: 744.5;Proximal enterocytes: 1051.2;Respiratory ciliated cells: 1771.2;Undifferentiated cells: 495.4" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "OE19: 109.8;T-47d: 339.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 67000 "Cluster 9: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" 0.6 0.1 0.0 11.0 0.0 0.0 69.6 0.0 0.2 25.0 0.1 219.9 167.2 8.7 0.0 1.5 225.2 48.3 0.1 0.1 0.4 2.5 0.3 152.7 0.2 2.0 3.4 0.3 10.7 0.0 21.2 0.8 1.0 4.8 214.9 0.0 30.9 0.8 0.0 1.5 237.6 8.7 0.7 0.3 99.9 0.2 0.2 0.0 7.3 0.0 0.8 27.6 0.2 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 109.8 0.0 0.0 0.0 2.3 8.1 0.0 1.3 0.4 0.0 0.6 0.0 0.0 339.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 2.0 3.4 1.0 0.7 0.2 0.5 0.7 333.3 408.1 0.3 1.4 2.7 12.5 108.5 0.0 0.0 105.1 51.9 0.1 31.5 319.9 29.5 0.0 3.4 0.7 380.0 1.9 30.4 0.0 861.1 7.4 1.9 112.7 0.0 0.2 71.4 3.3 5.3 71.4 39.2 20.8 0.0 0.0 0.0 0.5 0.0 0.2 701.9 134.3 0.0 0.3 0.0 0.3 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 16.6 744.5 0.0 0.4 7.1 1051.2 0.0 1771.2 0.0 0.0 0.0 27.9 0.0 0.1 0.0 9.8 2.2 4.1 0.0 495.4 117.9 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AIFM1 "AIF, AUNX1, CMTX4, DFNX5, NAMSD, PDCD8" ENSG00000156709 "Apoptosis inducing factor mitochondria associated 1" O95831 X 130124666-130165879 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "DNA-binding, Oxidoreductase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Dwarfism, Mental retardation, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.4;Proximal tubular cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003764, HPA030611" Enhanced Supported Mitochondria NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003764: AB_289587, HPA030611: AB_2673549" "unprognostic (3.00e-3)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-2)" "unprognostic (3.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (3.11e-2)" "unprognostic (2.54e-3)" "unprognostic (2.81e-3)" "prognostic favorable (4.42e-10)" "unprognostic (1.76e-2)" "unprognostic (1.14e-1)" "unprognostic (5.04e-2)" "unprognostic (2.11e-2)" 21.0 65.2 10.5 17.6 11.2 11.8 17.8 11.9 12.8 15.7 24.7 34.3 52.9 15.3 8.9 20.8 22.1 10.1 107.7 10.9 11.6 97.3 110.6 13.9 16.2 11.3 11.0 11.9 27.8 29.7 16.2 10.3 11.4 14.8 15.9 8.5 18.6 7.6 68.9 15.2 29.9 10.1 11.2 20.3 41.2 30.3 12.1 18.5 14.7 25.2 11.0 18.4 13.4 11.6 52.8 95.4 22.6 85.2 24.1 14.6 50.0 28.6 19.0 33.5 25.2 55.8 36.4 105.0 113.3 17.5 39.3 47.2 61.3 33.3 12.7 48.2 73.4 61.6 59.1 68.9 34.0 51.5 63.5 26.1 21.7 34.5 22.0 12.1 27.2 83.4 62.6 50.7 13.1 96.7 57.6 74.5 24.4 53.6 65.1 55.6 31.7 132.7 60.8 36.6 46.0 28.2 35.5 68.0 67.5 13.2 46.0 40.8 31.7 20.5 20.4 63.9 58.7 24.2 45.0 47.5 25.3 86.4 33.4 4.1 21.0 14.1 11.8 26.6 13.1 14.6 12.8 14.6 31.7 10.3 12.7 12.6 2.4 20.7 24.8 14.7 17.9 12.4 10.5 11.2 11.9 12.8 10.9 11.6 11.3 11.0 11.4 11.2 12.1 11.6 12.6 16.0 20.1 17.0 17.1 8.7 8.2 25.0 9.1 19.3 13.0 8.3 165.4 22.8 21.2 40.5 22.9 58.0 14.2 31.6 92.0 24.9 1.8 36.7 17.3 11.5 9.6 26.3 10.8 20.5 29.0 16.4 27.0 50.4 10.8 33.1 14.3 92.3 38.0 15.2 12.1 24.0 34.6 14.4 7.4 4.9 17.4 16.8 10.6 8.4 16.6 17.2 20.6 8.0 19.6 18.0 18.9 17.3 19.2 7.9 45.6 326.1 21.3 48.1 6.6 11.3 39.3 10.2 32.0 17.1 6.8 39.7 15.8 45.9 37.2 9.8 AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 441.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 393.1;Exocrine glandular cells: 722.5;Proximal enterocytes: 576.9;Proximal tubular cells: 601.8" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.0;gdT-cell: 102.6" "Group enriched" "Detected in many" 4 "granulocytes: 244.0;T-cells: 102.6" "Cell line enhanced" "Detected in many" "A549: 1615.1;ASC diff: 811.9;Hep G2: 699.6;OE19: 3025.3;RT4: 639.2" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" 164.4 50.2 31.1 25.4 34.6 42.3 115.2 32.1 42.4 21.9 30.2 185.9 441.3 25.9 4.4 53.2 42.1 261.1 42.9 31.5 35.6 177.7 268.0 48.3 7.6 30.3 33.9 17.8 36.4 22.5 10.4 4.7 32.3 10.3 98.0 19.1 40.5 19.4 116.9 27.0 270.9 39.2 30.3 3.8 237.4 10.0 31.5 37.4 26.4 34.8 6.6 84.7 22.2 31.1 0.1 1615.1 1.1 413.0 811.9 292.2 1.0 0.0 21.4 0.4 1.4 47.6 24.5 0.2 78.7 19.4 45.0 11.5 1.5 28.8 1.1 3.0 0.5 3.2 438.4 699.6 4.3 0.7 0.2 160.9 57.1 20.0 0.7 25.8 28.1 3.4 10.8 0.0 42.6 3.8 9.8 2.6 0.7 3025.3 4.3 3.3 9.6 43.7 149.0 639.2 1.0 2.9 232.2 0.0 0.3 0.9 0.5 0.2 221.7 5.2 4.7 87.8 3.1 0.7 0.7 0.3 45.8 62.8 4.4 244.0 2.9 4.8 102.6 0.9 6.9 0.0 19.0 18.7 2.1 0.5 11.6 8.9 7.3 21.1 1.4 39.6 21.4 42.4 31.1 34.6 32.1 42.4 31.5 35.6 30.3 33.9 32.3 30.3 31.5 31.1 144.2 44.8 5.3 4.9 4.3 12.0 3.7 393.1 2.8 2.0 15.8 5.5 3.9 0.0 172.9 36.8 0.0 0.4 64.4 133.8 43.0 114.6 3.3 67.5 4.5 67.5 19.2 34.9 2.5 722.5 0.0 44.3 158.0 66.4 5.7 0.1 0.0 0.0 1.6 1.7 3.2 65.9 61.1 0.0 14.0 4.9 78.3 14.8 21.4 7.5 4.1 132.7 202.9 14.6 0.0 266.1 219.6 106.8 3.1 1.3 576.9 601.8 112.8 5.3 26.3 15.5 20.3 0.5 4.3 20.2 10.7 0.0 14.4 7.8 196.9 46.4 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1500.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 389.4;Hepatocytes: 624.4;Leydig cells: 406.4;Proximal tubular cells: 375.4;Respiratory ciliated cells: 583.7" "Cancer enhanced" "Detected in all" "liver cancer: 399.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.3" "Lineage enriched" "Detected in many" 33 "monocytes: 87.3" "Cell line enhanced" "Detected in many" "A549: 4019.8;Hep G2: 1269.3;RPTEC TERT1: 710.6" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 378.3" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Cytosol "CAB020690: , HPA002123: AB_1844722" "unprognostic (8.46e-3)" "prognostic favorable (7.77e-5)" "unprognostic (5.59e-2)" "unprognostic (1.69e-1)" "unprognostic (1.49e-2)" "unprognostic (8.71e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (4.53e-2)" "unprognostic (6.83e-2)" "unprognostic (4.45e-2)" "unprognostic (3.73e-1)" "unprognostic (3.24e-3)" "unprognostic (2.20e-1)" "unprognostic (2.36e-1)" "unprognostic (2.96e-2)" "unprognostic (1.90e-3)" 109.4 182.4 51.3 28.4 71.9 31.8 64.3 125.1 72.4 121.8 35.7 218.2 549.7 139.3 583.4 41.3 184.3 175.4 53.7 64.6 62.1 335.4 1500.8 142.6 31.2 93.4 370.7 222.7 498.1 24.3 164.4 32.0 84.7 57.2 88.8 0.4 104.5 245.4 66.7 17.2 304.3 117.0 104.2 77.5 568.5 149.5 74.5 19.8 211.7 83.0 21.6 31.6 90.7 106.1 0.0 4019.8 0.4 0.0 22.4 0.2 1.4 139.6 0.0 0.1 0.1 136.2 0.0 0.1 50.5 0.0 0.3 2.6 0.0 0.2 0.1 0.4 0.1 232.1 0.6 1269.3 13.7 0.6 0.3 6.7 0.1 0.0 0.0 0.3 143.0 0.0 16.9 0.0 153.3 7.2 0.2 1.8 0.7 7.2 0.4 0.5 44.0 1.8 710.6 1.1 0.3 1.4 0.3 0.4 2.9 0.2 0.0 0.5 0.7 0.0 3.5 0.5 0.3 0.4 0.2 1.0 0.0 1.7 0.4 0.0 87.3 1.4 0.0 14.9 0.0 0.0 0.2 0.1 1.4 0.7 0.0 0.0 2.6 0.0 1.1 1.0 0.0 30.3 51.3 71.9 125.1 72.4 64.6 62.1 93.4 370.7 84.7 104.2 74.5 106.1 4.9 96.1 107.6 31.3 6.9 2.7 18.3 168.3 1.2 0.4 12.6 1.7 4.3 187.3 361.1 115.8 0.0 1.7 0.1 20.2 389.4 71.6 12.6 6.3 125.2 26.4 54.9 96.1 3.5 349.7 1.0 102.7 258.4 8.1 158.9 0.2 133.5 624.4 134.4 0.0 0.5 168.9 138.4 109.6 5.1 37.8 406.4 61.7 7.2 17.8 46.0 0.0 2.1 0.0 0.7 128.4 77.4 207.3 1.3 2.0 267.4 375.4 583.7 0.3 26.3 334.2 28.6 8.6 4.6 21.5 3.1 2.5 8.8 129.6 131.7 26.5 ALDH3B2 ALDH8 ENSG00000132746 "Aldehyde dehydrogenase 3 family member B2" P48448 11 67662160-67681224 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 73.0;esophagus: 152.2;skin 1: 123.0;vagina: 41.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 26.2;Endometrial ciliated cells: 12.6;Glandular and luminal cells: 28.1;Squamous epithelial cells: 53.3;Suprabasal keratinocytes: 14.8;Syncytiotrophoblasts: 14.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 71.9;SK-BR-3: 70.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045132 Approved NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA045132: AB_10795993" "unprognostic (2.25e-1)" "unprognostic (2.41e-1)" "unprognostic (1.65e-1)" "unprognostic (8.65e-2)" "unprognostic (2.13e-1)" "unprognostic (6.09e-2)" "unprognostic (3.12e-2)" "unprognostic (6.32e-2)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.61e-1)" "unprognostic (1.15e-2)" "unprognostic (5.92e-2)" 0.3 0.0 0.1 0.1 0.0 0.2 73.0 0.0 0.0 14.4 0.0 0.1 0.1 0.8 6.8 152.2 4.6 0.3 0.1 0.0 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.3 5.2 0.1 3.2 0.0 3.3 0.1 0.5 17.3 4.8 0.3 123.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 2.4 0.0 0.0 21.1 8.3 41.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 7.9 0.0 0.0 0.1 0.0 1.3 3.5 3.3 0.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.3 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.9 6.8 0.0 0.1 9.0 0.0 0.0 0.0 1.9 0.0 13.0 0.0 0.1 0.0 70.7 0.1 0.4 15.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 1.7 1.2 4.9 1.2 0.0 26.2 7.2 0.4 0.0 7.3 5.5 0.0 10.6 0.2 0.0 1.9 1.1 0.0 12.6 2.6 0.2 0.0 0.0 0.1 0.2 10.6 0.2 0.0 28.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.0 0.0 0.8 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 53.3 14.8 14.6 0.2 0.0 0.0 7.6 ALOX5 5-LOX ENSG00000012779 "Arachidonate 5-lipoxygenase" P09917 10 45374176-45446119 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Leukotriene biosynthesis" "Dioxygenase, Hydrolase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 72.8;lymphoid tissue: 93.9" "Cell type enhanced" "Detected in many" "B-cells: 63.7;granulocytes: 201.3;Hofbauer cells: 85.0;Kupffer cells: 78.5;Macrophages: 86.5;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 13.9;Daudi: 40.9;HMC-1: 24.0;U-266/70: 30.8;U-698: 11.0" "Region enriched" "Detected in single" 4 "white matter: 2.9" "Low region specificity" "Detected in all" HPA071285 Enhanced Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA071285: AB_2686379" "unprognostic (2.57e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.75e-2)" "unprognostic (7.98e-3)" "unprognostic (1.26e-1)" "unprognostic (5.32e-2)" "unprognostic (8.69e-2)" "unprognostic (1.86e-2)" "unprognostic (6.91e-2)" "unprognostic (5.04e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.59e-3)" "unprognostic (4.22e-2)" "unprognostic (1.53e-1)" "prognostic favorable (7.18e-4)" 16.8 8.4 1.4 8.4 1.1 31.1 12.7 2.8 2.9 6.1 1.0 11.0 3.0 6.9 0.3 10.7 11.1 3.4 6.7 1.2 1.8 8.3 5.5 72.8 6.7 4.1 2.5 2.6 23.2 0.9 3.2 3.6 2.7 11.8 2.3 0.1 14.1 1.5 2.1 5.6 35.8 4.9 2.5 93.9 9.3 2.1 2.2 2.6 4.7 3.7 8.9 40.0 7.9 4.2 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 7.4 40.9 0.7 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 8.6 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.1 0.0 2.7 0.0 5.2 0.7 0.0 0.0 0.2 0.0 0.1 0.1 0.6 0.0 0.0 2.2 0.0 0.0 30.8 2.8 11.0 0.0 0.1 0.0 462.5 225.6 317.6 0.3 198.4 0.6 133.9 5.3 1.7 119.7 98.5 0.7 0.5 457.8 0.2 210.5 2.4 1.2 136.1 1.4 1.1 2.8 2.9 1.2 1.8 4.1 2.5 2.7 2.5 2.2 4.2 0.7 16.0 38.4 1.3 63.7 1.1 7.3 0.2 1.2 1.3 7.3 4.3 2.2 12.8 9.5 9.2 2.1 0.7 1.7 1.7 0.0 20.9 0.5 0.7 0.5 3.0 7.1 1.7 2.8 21.6 2.0 1.7 13.7 4.4 201.3 2.2 3.6 1.1 85.0 0.0 1.1 2.0 14.2 78.5 17.8 1.1 0.3 86.5 0.0 47.8 59.5 0.7 4.1 4.0 1.4 18.4 0.6 0.0 13.8 4.0 9.4 0.2 2.6 0.3 13.1 0.3 1.1 0.3 1.1 9.2 1.4 4.1 5.9 0.7 3.2 45.3 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 AMPD1 "MAD, MADA" ENSG00000116748 "Adenosine monophosphate deaminase 1" P23109 1 114673090-114695618 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 559.2;tongue: 211.4" "Group enriched" "Detected in some" 6 "Plasma cells: 43.8;Skeletal myocytes: 13.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 29 "U-266/70: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA026478, HPA028080" Enhanced "Intracellular and membrane" NA NA 38000 "Cluster 37: B-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 37: Myocytes - Muscle contraction" "HPA026478: AB_10599969, HPA028080: AB_10600776" "unprognostic (1.98e-3)" "unprognostic (1.43e-3)" "unprognostic (8.75e-3)" "unprognostic (8.03e-2)" "unprognostic (1.95e-2)" "unprognostic (5.61e-3)" "unprognostic (8.21e-2)" "unprognostic (4.29e-3)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.36e-5)" "unprognostic (1.68e-1)" "unprognostic (3.70e-1)" "unprognostic (3.36e-1)" "unprognostic (4.02e-1)" 0.1 0.1 0.0 0.5 0.0 0.3 3.0 0.0 0.0 0.2 0.0 5.6 16.4 0.2 0.0 5.8 0.4 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.5 0.0 0.0 1.0 0.1 0.3 0.0 0.0 0.0 3.5 5.5 0.0 4.4 0.9 559.2 0.0 7.5 0.1 0.0 1.6 3.7 0.1 0.0 0.4 0.1 211.4 2.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.8 1.9 0.0 0.0 0.0 3.0 4.2 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 ANKRD30A NY-BR-1 ENSG00000148513 "Ankyrin repeat domain 30A" Q9BXX3 10 37125725-37384111 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "breast: 38.1" "Group enriched" "Detected in some" 4 "Breast glandular cells: 295.9;Breast myoepithelial cells: 84.8" "Cancer enriched" "Detected in single" 37 "breast cancer: 11.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 32 "A549: 2.7;U-266/70: 10.4" HPA071849 Uncertain Nucleoli NA NA "Cluster 5: Breast - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoli "HPA071849: " "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (1.01e-7)" "unprognostic (1.41e-1)" "unprognostic (5.93e-1)" 1.0 0.0 0.0 0.0 0.0 0.0 38.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 295.9 84.8 0.3 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 16.3 0.0 0.4 1.0 0.0 0.0 1.5 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 8.5 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 45.8 1.7 0.0 0.0 0.3 0.3 0.1 0.0 0.0 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 215.4;HHSteC: 197.9;LHCN-M2: 221.0;U-2197: 176.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 13000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" 60.9 30.0 4.1 35.4 4.1 18.7 18.7 3.6 6.4 52.2 5.0 39.9 23.0 95.4 21.9 24.5 31.2 54.9 31.8 3.6 5.0 17.1 34.4 24.7 16.2 4.7 5.0 75.0 4.6 27.8 1.6 90.0 4.2 110.2 42.7 1.6 10.1 90.3 6.1 6.1 29.6 108.3 5.5 18.3 23.2 8.4 4.0 10.7 4.9 21.7 16.1 53.1 12.0 4.4 15.5 1.9 34.6 6.6 215.4 118.0 3.1 48.3 124.6 17.5 19.9 0.6 11.8 0.0 0.8 76.8 11.4 4.5 4.4 49.7 66.9 2.2 4.2 12.2 1.3 4.8 197.9 51.6 29.5 145.3 15.2 132.7 68.3 150.2 52.6 1.6 27.1 35.8 221.0 0.0 1.1 57.1 5.7 21.7 70.3 2.4 19.8 9.0 12.0 14.4 30.6 41.2 4.9 0.6 8.2 16.3 0.7 11.0 69.8 155.7 9.7 176.7 103.4 3.1 0.0 0.1 78.6 39.4 49.0 72.7 17.5 61.6 12.8 9.5 13.8 23.5 21.4 13.1 32.2 9.4 11.3 5.9 54.4 4.3 18.0 32.2 40.4 14.0 4.1 4.1 3.6 6.4 3.6 5.0 4.7 5.0 4.2 5.5 4.0 4.4 6.4 12.8 10.0 23.5 25.7 7.0 15.5 6.5 4.0 6.9 4.0 2.2 24.9 4.3 10.2 0.0 29.2 18.3 24.9 42.4 3.9 4.2 2.3 7.7 69.3 15.5 18.6 6.3 25.4 6.7 29.0 58.7 4.1 6.1 60.1 8.9 15.0 24.9 17.7 0.0 2.1 15.1 4.1 13.4 28.9 5.3 39.1 28.3 1.8 45.9 53.7 6.9 4.1 19.1 0.8 45.5 28.9 63.9 14.1 13.9 16.9 2.5 4.9 21.4 39.5 32.5 28.5 0.6 2.1 0.9 4.3 6.6 24.4 18.3 13.3 1.6 ANXA5 "ANX5, ENX2" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1156.8;Extravillous trophoblasts: 1125.1;Syncytiotrophoblasts: 1140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear membrane" "CAB003677: AB_425305, HPA035330: AB_2674574" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (9.70e-2)" "prognostic favorable (3.64e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (3.01e-5)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.33e-3)" "unprognostic (3.09e-1)" "unprognostic (6.04e-2)" "unprognostic (6.49e-3)" "unprognostic (4.54e-1)" "prognostic unfavorable (9.29e-7)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.02e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.26e-4)" 490.6 286.5 111.7 241.7 126.3 96.2 314.0 136.9 144.7 429.1 137.7 181.9 96.5 288.7 162.6 135.1 225.0 273.1 213.9 106.4 134.7 216.2 149.5 299.0 136.2 151.2 129.6 224.7 162.9 133.7 176.7 466.0 150.4 211.7 155.5 78.1 273.8 250.5 85.2 132.5 130.9 370.3 134.3 175.7 186.0 110.4 154.3 63.3 182.9 114.8 135.2 298.1 178.6 157.3 463.5 339.6 438.0 256.1 2094.3 1645.5 503.4 1582.7 1464.9 841.3 744.8 246.2 200.6 35.7 282.9 2224.8 581.7 165.4 287.3 727.6 762.2 335.1 171.2 105.0 281.6 647.4 1213.9 221.1 178.3 945.5 344.7 705.1 665.9 927.4 1120.9 25.2 106.0 271.8 2133.5 306.7 225.5 75.1 231.9 417.7 718.5 8.2 1014.5 72.6 1368.9 66.3 117.1 141.4 579.7 227.6 1515.2 872.3 201.5 261.2 830.6 1322.1 632.1 955.2 478.0 240.8 308.6 76.0 847.8 123.5 1586.2 122.2 725.8 359.9 104.8 830.5 136.0 127.3 158.8 131.9 745.6 89.5 51.3 74.6 157.9 48.4 798.0 91.2 289.9 773.3 111.7 126.3 136.9 144.7 106.4 134.7 151.2 129.6 150.4 134.3 154.3 157.3 286.5 243.6 233.9 13.7 85.0 199.3 266.4 395.9 76.2 6.8 101.6 107.4 88.3 265.9 257.2 132.4 25.0 1156.8 53.2 15.6 297.4 703.5 16.2 239.7 318.1 287.7 48.6 29.0 15.4 338.2 1125.1 564.7 91.3 312.6 148.7 177.5 186.4 54.8 753.2 13.5 7.1 110.9 187.2 446.5 705.1 41.4 379.9 544.0 352.2 45.0 412.5 161.4 13.4 23.1 26.8 501.1 31.2 366.3 203.1 473.8 15.3 194.3 268.9 30.0 295.9 443.1 377.2 15.9 28.6 101.1 140.8 1140.8 122.0 185.7 43.2 188.2 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AP1M1 "AP47, CLAPM2" ENSG00000072958 "Adaptor related protein complex 1 subunit mu 1" Q9BXS5 19 16197854-16245906 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045256 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA045256: AB_10960697" "unprognostic (5.10e-2)" "unprognostic (3.71e-2)" "unprognostic (4.70e-3)" "unprognostic (2.85e-1)" "unprognostic (5.19e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-2)" "unprognostic (3.52e-2)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.37e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (1.02e-2)" "unprognostic (3.02e-1)" "unprognostic (2.96e-2)" "unprognostic (1.56e-1)" 49.5 47.2 30.1 30.7 31.0 58.5 37.9 22.3 36.3 32.2 22.0 37.7 32.1 38.8 9.2 29.6 29.8 21.4 39.9 33.0 31.0 39.6 81.0 31.9 36.9 26.6 30.0 31.7 18.8 20.1 24.0 27.5 33.5 25.3 12.6 17.3 21.6 24.8 44.4 30.8 31.0 35.4 23.1 37.6 27.3 60.8 25.0 37.8 23.7 29.0 28.2 38.3 29.1 25.9 63.3 70.2 69.3 65.3 82.7 80.9 39.1 69.6 74.1 99.5 103.3 83.9 48.6 49.8 78.7 76.6 64.4 35.1 54.2 56.9 111.3 85.5 122.3 80.9 63.4 114.6 67.1 91.5 96.9 83.5 42.2 89.2 59.8 65.4 95.6 69.8 40.3 98.0 109.5 75.8 131.2 55.4 56.9 22.3 162.7 87.9 56.7 67.3 54.9 45.2 44.4 99.4 56.8 34.4 64.0 36.9 41.0 73.1 83.1 111.8 45.6 151.7 134.3 104.6 141.6 54.9 125.5 112.8 88.7 89.4 142.3 243.9 104.8 180.7 105.6 99.8 103.4 111.2 121.6 92.3 115.1 147.0 101.8 133.1 235.7 131.2 161.8 174.3 30.1 31.0 22.3 36.3 33.0 31.0 26.6 30.0 33.5 23.1 25.0 25.9 17.4 41.7 31.2 12.7 30.6 4.6 7.4 13.2 11.4 35.4 11.3 10.9 17.9 14.3 15.2 12.9 20.9 32.1 30.5 8.3 15.6 21.1 32.5 10.6 27.2 22.7 19.8 21.7 11.8 18.2 40.4 28.1 8.6 14.8 27.1 19.0 21.8 41.9 42.6 42.1 11.7 7.3 6.1 36.0 13.3 92.1 23.0 30.2 10.6 5.6 34.9 18.3 38.1 4.5 12.8 31.2 5.9 19.9 24.5 6.2 25.1 23.6 13.9 40.2 0.0 26.1 22.8 61.9 23.3 12.6 7.1 17.5 32.9 17.7 9.0 4.6 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" 20.1 18.0 3.5 1.3 5.1 4.5 16.6 10.8 9.9 20.3 1.4 23.0 5.4 17.9 1.5 12.7 18.1 2.0 19.1 5.5 3.5 34.4 29.9 18.9 3.2 0.9 2.1 17.5 25.3 3.7 25.6 5.2 3.0 20.3 4.9 5.8 14.6 4.0 14.1 14.5 19.6 5.6 0.0 57.6 20.6 15.5 3.3 3.8 13.9 1.6 2.5 19.0 15.7 1.4 7.5 2.9 3.7 10.7 13.8 14.2 9.1 10.2 3.3 6.0 4.9 1.3 7.3 7.4 8.7 12.3 5.7 8.9 8.9 5.6 3.9 5.5 23.2 2.1 10.4 3.9 5.3 2.8 4.9 16.8 6.1 3.1 6.1 14.8 8.5 5.0 5.9 4.7 6.3 0.4 2.6 3.2 2.0 9.1 17.9 4.2 2.6 8.1 9.2 6.2 12.3 10.0 11.4 9.2 1.7 6.3 5.4 0.8 13.3 1.9 2.3 2.8 5.2 4.3 3.9 5.3 4.0 3.7 3.1 1.5 1.7 1.5 1.1 1.7 0.5 0.5 1.1 0.6 1.4 1.0 1.1 1.2 2.1 1.1 1.4 1.3 2.1 0.6 3.5 5.1 10.8 9.9 5.5 3.5 0.9 2.1 3.0 0.0 3.3 1.4 38.1 38.5 21.8 29.4 14.3 14.3 12.4 13.3 7.4 50.9 27.2 23.0 12.9 21.5 15.9 62.5 60.5 42.1 17.3 45.3 39.2 37.5 46.7 64.0 44.6 36.6 35.2 27.1 37.2 18.0 45.2 28.7 16.3 86.7 27.3 31.0 80.3 59.8 82.8 101.0 36.4 32.3 18.3 104.7 26.9 28.3 34.5 51.8 8.8 41.2 31.2 30.4 39.1 23.1 21.9 25.8 24.2 27.8 13.6 16.9 43.5 70.4 23.5 69.2 26.3 20.7 22.6 72.7 28.0 11.2 11.4 28.5 19.7 30.5 37.0 11.5 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.3" "Cell type enhanced" "Detected in many" "B-cells: 6.7;NK-cells: 9.2;Plasma cells: 6.4;T-cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 11.8;Karpas-707: 46.7" HPA055116 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA055116: AB_2682701" "prognostic favorable (2.51e-5)" "prognostic favorable (1.31e-4)" "unprognostic (2.69e-2)" "prognostic favorable (4.47e-4)" "unprognostic (2.62e-2)" "unprognostic (3.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (2.45e-2)" "unprognostic (4.50e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.76e-7)" "unprognostic (4.76e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "prognostic favorable (3.01e-4)" 1.7 2.2 1.2 8.6 1.2 2.5 1.8 1.5 1.2 3.5 1.1 3.5 3.8 3.3 3.0 1.7 5.2 4.1 1.2 1.0 0.9 1.6 1.2 3.3 15.3 1.6 1.2 4.1 0.5 1.1 0.9 2.2 1.3 2.6 4.3 0.3 2.8 2.3 0.9 1.4 5.3 2.4 1.3 12.0 5.3 2.4 1.1 7.7 1.9 1.2 13.8 4.6 2.7 1.4 0.5 0.0 0.3 2.1 3.1 5.5 1.9 0.3 3.3 3.9 4.4 0.9 5.3 6.1 0.9 4.4 2.5 0.6 0.3 0.0 1.4 11.1 1.2 10.7 0.1 0.0 8.3 1.5 11.8 3.6 0.5 6.3 0.0 0.0 2.9 9.0 2.7 46.7 0.2 0.0 5.2 3.4 0.8 0.0 0.5 4.3 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.1 1.7 1.4 0.1 0.5 1.1 0.1 1.2 0.6 0.0 3.2 3.9 0.8 1.6 3.3 1.5 4.8 1.3 3.5 8.0 3.5 5.2 6.7 5.8 7.3 0.8 6.8 2.7 3.6 1.7 4.9 6.5 5.4 5.8 3.4 1.2 1.2 1.5 1.2 1.0 0.9 1.6 1.2 1.3 1.3 1.1 1.4 0.9 3.2 0.5 0.0 6.7 1.0 1.5 0.9 0.0 0.2 0.3 0.6 0.4 5.7 1.1 1.8 0.0 1.3 3.8 3.0 0.0 0.2 0.5 1.0 0.8 1.9 1.8 1.7 0.0 0.2 0.7 1.8 2.6 0.6 0.0 1.1 2.5 0.2 2.5 0.0 0.0 3.6 0.0 3.4 1.0 0.0 3.1 1.1 3.6 2.8 1.2 0.3 9.2 0.5 0.0 0.2 0.1 1.9 6.4 1.4 1.3 0.3 2.7 0.5 0.0 0.9 1.4 0.2 0.4 0.2 0.9 0.5 8.7 0.8 2.1 2.6 APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;dendritic cells: 9.6;Hofbauer cells: 4.9;monocytes: 10.5;NK-cells: 6.2;T-cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HDLM-2: 2.7;Karpas-707: 6.9;U-266/70: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" 0.7 0.8 0.3 2.3 0.5 3.6 0.6 1.0 0.7 0.7 0.0 1.8 0.5 0.8 3.6 1.1 1.3 1.6 0.5 0.3 0.3 0.8 0.6 2.4 3.8 0.7 0.4 0.5 0.3 0.6 0.7 1.0 0.6 0.7 3.3 0.6 0.9 1.5 0.6 0.5 1.2 1.2 0.2 3.1 0.9 1.6 0.5 2.9 0.7 0.0 2.1 1.4 0.6 0.5 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.2 0.0 0.0 0.2 2.8 1.0 0.3 0.0 0.1 0.0 0.6 0.0 2.7 0.3 0.7 0.1 0.0 0.2 0.0 2.0 1.8 1.6 0.2 0.2 0.2 0.0 0.1 0.0 6.9 0.9 0.9 1.4 0.2 0.0 0.0 0.0 1.6 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 4.8 0.7 0.2 0.2 1.2 0.1 0.1 0.3 0.0 23.2 0.5 9.4 1.4 12.1 19.4 0.2 0.4 0.6 8.9 0.0 19.7 1.6 0.0 11.9 4.7 0.3 0.5 1.0 0.7 0.3 0.3 0.7 0.4 0.6 0.2 0.5 0.5 0.4 0.0 4.2 0.0 1.6 0.1 0.6 0.9 1.2 0.0 0.2 0.3 0.1 0.0 2.4 0.0 0.0 6.6 9.6 0.1 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.1 3.8 0.1 0.4 0.2 4.9 0.0 0.2 0.0 2.0 1.0 0.6 0.5 0.0 1.0 0.0 0.0 10.5 0.0 6.2 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.9 0.1 0.2 0.2 0.0 1.5 20.8 0.0 0.0 0.5 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 ARFGEF3 "BIG3, C6orf92, dJ171N11.1, KIAA1244, PPP1R33" ENSG00000112379 "ARFGEF family member 3" Q5TH69 6 138161939-138344663 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.4;salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 114.6;Excitatory neurons: 200.9;Inhibitory neurons: 207.8;Oligodendrocyte precursor cells: 173.9;Oligodendrocytes: 378.1" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 14.8;RH-30: 13.4;RT4: 19.4;SK-BR-3: 22.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036350 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA036350: AB_10672084" "prognostic unfavorable (8.20e-4)" "unprognostic (4.31e-2)" "unprognostic (9.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.20e-2)" "unprognostic (4.53e-2)" "unprognostic (4.30e-3)" "unprognostic (1.21e-2)" "unprognostic (7.41e-2)" "unprognostic (7.82e-2)" "unprognostic (3.46e-2)" "unprognostic (4.93e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (2.38e-1)" "unprognostic (8.87e-2)" "unprognostic (1.69e-2)" 1.2 3.8 13.4 0.7 16.4 0.4 7.9 20.1 17.7 5.0 0.0 4.2 2.2 0.7 0.9 0.4 2.2 1.7 1.0 16.7 13.0 2.1 0.1 6.4 0.2 11.1 17.7 0.1 8.7 15.8 7.0 1.4 14.4 12.0 4.8 2.8 18.0 1.0 0.2 1.2 1.9 0.7 7.5 0.4 10.0 0.6 15.2 0.1 1.9 0.7 0.2 3.4 0.4 28.4 8.0 3.1 0.0 0.6 0.0 0.0 4.7 0.3 0.2 0.2 0.0 0.1 0.4 0.0 3.1 0.3 2.7 2.6 3.8 2.0 0.0 0.0 4.9 0.0 1.5 0.9 0.0 3.0 0.0 0.0 0.9 0.0 0.9 3.5 4.1 2.7 0.0 4.9 0.0 14.8 0.0 0.0 2.7 8.5 3.4 0.6 13.4 2.6 2.6 19.4 6.9 0.0 7.8 22.2 0.9 0.3 4.4 0.0 0.4 0.2 2.2 0.0 7.9 1.7 6.7 0.0 3.2 1.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 16.4 20.1 17.7 16.7 13.0 11.1 17.7 14.4 7.5 15.2 28.4 9.4 16.0 114.6 34.3 0.5 0.0 18.8 0.0 6.2 19.0 39.9 12.6 6.4 14.3 44.6 3.7 0.0 16.5 0.8 2.5 3.9 11.4 83.0 8.6 1.4 11.9 66.7 2.7 200.9 24.7 2.4 4.1 41.3 17.7 2.5 0.1 8.2 0.3 1.4 11.8 207.8 44.2 0.0 0.0 0.0 22.0 0.0 0.5 0.0 36.5 2.0 0.9 0.0 173.9 378.1 14.2 8.4 0.0 0.9 67.6 2.5 0.3 37.2 3.3 0.0 3.5 0.9 4.1 1.1 3.0 0.0 6.2 0.8 0.1 13.2 42.7 ARFIP2 POR1 ENSG00000132254 "ADP ribosylation factor interacting protein 2" P53365 11 6474683-6481479 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032985, HPA038156" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli fibrillar center, Golgi apparatus" "CAB032985: AB_2058811, HPA038156: AB_10697243" "unprognostic (2.32e-1)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "prognostic favorable (2.00e-5)" "unprognostic (8.44e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-3)" "unprognostic (2.50e-1)" "unprognostic (2.96e-1)" "unprognostic (1.76e-1)" "unprognostic (5.70e-3)" "unprognostic (3.11e-1)" "prognostic favorable (9.53e-4)" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.32e-2)" "unprognostic (9.48e-3)" 19.8 29.3 31.7 18.6 32.3 22.8 50.7 32.5 35.2 36.3 36.2 36.8 32.9 27.2 34.0 31.4 39.3 23.9 17.9 32.1 31.4 27.0 34.6 24.4 22.4 31.2 31.4 29.4 49.4 46.4 40.7 29.7 31.9 46.6 48.1 28.3 57.7 28.2 15.2 32.8 30.7 27.4 30.9 20.7 50.4 18.3 31.8 25.7 36.9 16.1 32.0 29.2 24.4 33.1 50.4 64.8 38.9 38.5 59.1 53.9 56.1 40.3 107.0 86.2 101.8 62.1 80.3 39.9 16.5 79.3 49.8 68.0 49.4 84.1 70.0 30.9 86.5 22.3 87.7 60.4 71.3 36.2 42.8 60.0 65.7 43.0 98.3 64.2 55.9 38.3 35.3 45.0 55.8 98.9 41.9 41.6 67.2 119.0 71.9 31.7 22.6 37.1 61.9 50.4 50.8 63.2 48.7 204.9 25.9 36.3 86.9 33.0 36.8 35.4 35.7 39.1 30.3 67.3 32.5 24.3 65.4 22.0 43.9 13.0 15.6 9.9 17.9 10.9 17.8 12.1 16.7 14.5 21.3 13.8 16.7 17.1 6.1 21.1 6.7 16.6 18.9 13.9 31.7 32.3 32.5 35.2 32.1 31.4 31.2 31.4 31.9 30.9 31.8 33.1 14.8 6.4 6.4 4.6 20.7 28.0 49.3 48.9 16.5 32.6 59.8 45.1 4.3 40.0 30.5 12.9 29.2 80.1 24.3 56.0 58.7 62.7 31.7 28.1 20.1 19.6 63.0 21.8 8.4 85.4 65.8 23.1 62.2 37.2 31.8 30.3 20.3 21.1 28.1 21.9 7.8 126.6 32.6 10.1 16.4 43.3 20.5 14.4 24.9 5.6 25.2 35.4 18.6 6.6 7.6 59.9 63.4 24.5 28.0 73.3 65.2 34.4 34.7 32.3 26.3 21.6 23.3 41.0 26.2 26.2 32.1 112.5 16.9 40.9 52.6 64.7 ARHGAP31 CDGAP ENSG00000031081 "Rho GTPase activating protein 31" Q2M1Z3 3 119294383-119420714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.8;Astrocytes: 123.1;Endothelial cells: 46.9;Langerhans cells: 54.1;Microglial cells: 125.5;Oligodendrocyte precursor cells: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 6.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 35.0;TIME: 38.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036380 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA036380: AB_10673129" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (9.90e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-2)" "unprognostic (1.11e-1)" "unprognostic (8.75e-3)" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (7.18e-3)" "unprognostic (5.86e-2)" "unprognostic (1.30e-1)" "prognostic favorable (8.45e-4)" "unprognostic (3.57e-2)" "unprognostic (6.32e-2)" "unprognostic (1.38e-1)" "unprognostic (7.79e-3)" 17.0 2.1 8.3 7.6 9.3 0.8 9.0 10.1 8.3 6.0 1.1 5.4 3.0 6.2 3.1 5.9 5.1 8.6 13.0 8.3 8.9 4.9 3.6 19.5 5.6 11.6 10.4 6.1 2.9 4.0 2.1 11.2 9.4 3.0 5.4 1.5 2.8 3.4 4.2 6.4 4.7 11.8 9.0 7.1 3.2 1.3 10.8 6.9 12.7 9.2 6.8 8.1 3.8 9.9 0.4 2.5 6.2 12.2 3.5 2.9 1.9 7.5 8.6 5.8 4.2 0.1 0.5 0.1 8.7 19.5 10.0 0.2 5.9 1.9 6.7 11.0 0.8 1.7 0.8 0.0 5.8 0.4 7.0 7.8 0.2 15.1 1.7 4.5 35.0 1.2 0.0 3.0 13.1 0.2 0.1 0.3 2.1 0.0 7.6 0.0 2.9 0.0 1.7 0.0 0.0 22.7 3.8 0.0 15.6 3.3 0.7 0.6 38.5 16.0 6.4 2.0 5.9 5.1 5.6 6.2 10.9 5.6 16.4 0.0 2.6 0.0 0.4 2.8 0.8 1.6 0.3 0.5 6.0 0.6 0.3 0.2 0.0 1.1 1.1 5.2 0.8 1.2 8.3 9.3 10.1 8.3 8.3 8.9 11.6 10.4 9.4 9.0 10.8 9.9 47.8 19.2 24.6 123.1 7.3 5.2 0.7 3.1 1.8 0.6 0.5 1.7 16.0 1.5 3.1 0.0 0.0 1.2 9.8 0.2 0.0 2.1 0.4 0.4 2.1 46.9 0.0 7.4 3.4 2.0 10.3 7.3 0.0 0.4 9.5 8.4 30.7 0.6 10.1 0.0 18.4 3.9 0.0 14.5 54.1 0.7 2.8 16.7 10.6 125.5 13.8 3.9 4.1 159.8 0.9 1.9 0.3 2.6 4.9 1.1 0.0 2.1 1.4 0.4 0.0 2.5 11.3 0.3 0.7 1.3 5.1 1.0 3.7 3.3 0.4 0.7 ARHGAP5 "GFI2, p190-B, p190BRhoGAP, RhoGAP5" ENSG00000100852 "Rho GTPase activating protein 5" Q13017 14 32076114-32159728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 381.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046993, HPA056507" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Cytosol" "HPA046993: AB_2679895, HPA056507: AB_2683158" "unprognostic (1.79e-1)" "unprognostic (2.03e-1)" "unprognostic (2.66e-3)" "unprognostic (6.77e-2)" "unprognostic (1.69e-1)" "unprognostic (3.75e-2)" "unprognostic (1.55e-2)" "unprognostic (6.23e-2)" "unprognostic (2.88e-1)" "unprognostic (2.18e-1)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "prognostic favorable (3.97e-8)" "unprognostic (9.79e-2)" "unprognostic (2.21e-1)" "unprognostic (2.13e-1)" "unprognostic (1.00e-2)" 23.7 27.3 54.3 19.8 55.5 10.9 27.3 66.4 53.6 26.2 12.1 29.5 35.3 28.0 24.7 66.5 23.2 32.7 62.8 47.5 52.7 43.0 31.8 28.0 14.6 42.9 52.0 47.3 29.7 48.1 10.0 37.1 43.2 30.5 26.3 57.8 59.8 29.3 14.0 30.8 38.9 23.4 45.6 42.9 29.4 46.5 50.6 18.3 68.5 24.7 18.5 32.8 15.7 80.4 61.0 48.5 47.3 69.8 60.7 42.4 27.3 37.1 45.6 22.1 32.9 62.2 58.0 17.9 32.1 47.0 37.2 63.3 46.0 39.9 42.7 18.0 26.6 26.9 30.1 91.2 41.5 16.5 15.5 47.5 78.8 20.7 77.1 54.3 27.4 33.3 24.3 51.8 36.3 31.9 36.4 0.8 23.7 67.1 57.7 38.9 58.2 3.5 48.4 159.5 73.2 28.6 99.6 52.7 74.6 52.5 54.8 1.1 44.6 40.8 60.6 33.9 27.6 19.7 41.5 2.8 20.5 17.5 113.1 2.2 1.4 0.0 3.1 0.7 3.8 6.1 5.5 3.0 5.3 5.3 5.7 3.5 0.5 5.9 1.2 7.6 5.0 2.0 54.3 55.5 66.4 53.6 47.5 52.7 42.9 52.0 43.2 45.6 50.6 80.4 50.9 192.3 71.9 381.9 40.7 94.2 144.2 52.1 130.9 97.2 52.8 53.3 301.2 58.6 70.2 58.8 114.7 27.5 27.0 85.0 54.8 50.2 42.0 92.1 77.9 42.9 61.8 28.6 81.7 46.1 14.5 65.1 59.7 136.3 5.1 30.0 37.5 51.1 19.0 65.6 140.7 56.8 46.8 19.0 45.4 66.8 104.4 44.2 67.6 65.6 18.6 103.3 14.4 139.7 205.6 75.0 93.5 100.4 35.7 104.2 89.6 60.1 78.4 92.7 59.2 103.1 65.9 128.5 75.6 94.0 70.3 13.4 29.2 77.3 51.1 180.9 ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.5;Cytotrophoblasts: 26.9;Ductal cells: 25.6;Pancreatic endocrine cells: 30.5;Urothelial cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.9;BEWO: 47.5;CACO-2: 30.9;HEK 293: 43.6;MCF7: 44.9;SK-BR-3: 40.1" "Not detected" "Not detected" HPA069694 Approved NA No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA069694: AB_2686173" "unprognostic (4.14e-1)" "unprognostic (1.21e-2)" "unprognostic (6.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-2)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (8.78e-3)" "unprognostic (9.58e-2)" "unprognostic (7.65e-6)" "unprognostic (8.59e-2)" "unprognostic (3.29e-1)" "unprognostic (2.32e-2)" "unprognostic (2.22e-2)" 1.0 0.4 0.4 1.2 0.2 0.6 9.5 1.1 1.0 3.0 4.2 10.0 1.7 1.6 11.4 7.5 6.8 4.3 0.1 0.4 0.1 28.1 1.1 4.4 0.7 0.2 0.1 0.3 10.3 5.6 6.4 7.4 0.4 13.5 7.1 0.3 23.2 8.3 0.1 2.0 3.6 0.3 0.1 9.0 6.5 3.3 0.4 0.5 17.5 0.0 1.1 2.0 2.9 0.2 26.9 0.4 0.4 0.2 0.0 0.4 47.5 0.2 3.1 0.0 0.2 30.9 13.5 0.2 1.6 0.0 0.4 19.1 8.5 21.9 0.2 0.1 43.6 0.0 0.9 0.4 0.1 0.1 0.4 0.2 9.3 0.2 0.4 0.6 0.1 0.5 0.9 0.7 0.1 44.9 0.1 0.2 6.7 19.3 0.0 0.0 0.1 0.4 11.6 17.9 2.7 0.1 0.0 40.1 0.9 9.9 17.5 0.3 0.4 0.0 1.5 0.1 0.2 3.9 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.2 1.1 1.0 0.4 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.1 3.2 12.5 0.0 0.5 0.6 20.5 5.9 3.4 0.4 8.9 2.4 0.8 4.3 9.1 18.4 4.2 26.9 0.7 8.6 0.0 25.6 2.3 4.1 1.0 1.1 7.2 0.0 0.0 10.8 2.1 1.3 7.1 12.3 0.0 0.5 0.4 0.0 3.3 0.0 0.0 11.7 12.2 1.0 0.4 3.2 0.3 0.6 0.0 0.0 0.1 0.7 5.2 0.0 0.0 30.5 12.1 0.4 0.6 20.0 1.2 2.0 4.1 0.7 0.0 1.7 0.7 0.1 3.9 6.0 0.3 7.0 1.0 6.9 17.0 20.8 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.1;Extravillous trophoblasts: 55.6;Gastric mucus-secreting cells: 67.2;Intestinal goblet cells: 49.6;Paneth cells: 68.2;Proximal enterocytes: 72.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.4;MCF7: 32.4;OE19: 38.2;SK-BR-3: 34.9" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" 3.8 0.5 1.4 2.7 2.0 0.0 4.8 3.0 2.0 3.5 5.2 19.7 44.0 1.1 2.7 17.9 2.5 11.1 1.0 1.1 4.0 17.7 6.5 3.3 0.2 5.3 2.6 1.3 11.1 8.0 11.4 5.0 5.1 9.4 11.9 2.7 17.0 5.7 1.4 5.9 34.2 0.5 2.6 0.8 28.1 3.2 3.3 0.4 10.0 1.5 2.0 5.0 9.0 3.3 18.3 6.8 1.8 0.2 0.0 0.0 12.6 0.3 0.4 0.5 1.4 20.7 56.4 0.0 13.5 0.1 3.4 18.8 3.0 12.1 0.1 0.0 6.3 0.0 8.8 16.2 0.6 0.0 0.1 0.3 11.4 1.2 0.6 1.2 0.1 0.3 2.3 0.0 0.1 32.4 0.0 0.4 13.8 38.2 0.4 0.0 0.0 2.7 14.2 9.1 9.8 1.8 3.6 34.9 0.8 7.1 15.7 0.6 0.0 0.2 4.0 0.3 0.4 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.0 3.0 2.0 1.1 4.0 5.3 2.6 5.1 2.6 3.3 3.3 0.6 9.6 5.4 2.0 0.5 3.2 15.0 9.1 14.2 1.1 8.1 4.6 1.6 12.8 11.7 16.5 6.2 3.2 0.1 101.1 15.6 16.5 0.1 4.3 0.8 0.8 10.2 0.0 0.4 12.7 55.6 0.8 67.2 9.9 0.0 17.3 0.4 4.3 1.2 3.3 0.5 49.6 20.3 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.6 36.7 0.0 0.5 5.2 28.6 68.2 0.0 2.8 3.6 72.1 11.5 6.5 8.8 0.0 0.0 3.0 0.3 3.9 12.2 1.0 6.7 0.5 2.0 40.0 13.3 ARHGEF37 FLJ41603 ENSG00000183111 "Rho guanine nucleotide exchange factor 37" A1IGU5 5 149551947-149634968 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 36.8;Oligodendrocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 9.3;neutrophil: 3.0" "Lineage enriched" "Detected in single" 12 "granulocytes: 9.3" "Cell line enhanced" "Detected in many" "EFO-21: 13.9;HaCaT: 26.1;hTCEpi: 33.8" "Region enhanced" "Detected in many" "cerebellum: 10.4" "Low region specificity" "Detected in all" "HPA043885, HPA053487" Uncertain Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA043885: AB_2678715, HPA053487: AB_2682167" "unprognostic (3.51e-2)" "unprognostic (1.58e-1)" "unprognostic (2.24e-1)" "unprognostic (3.92e-1)" "unprognostic (1.17e-1)" "unprognostic (6.87e-2)" "unprognostic (1.54e-3)" "unprognostic (1.54e-1)" "unprognostic (2.64e-1)" "unprognostic (6.93e-2)" "unprognostic (2.13e-3)" "unprognostic (1.16e-2)" "prognostic favorable (6.85e-4)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.50e-2)" "unprognostic (2.10e-1)" 4.2 3.8 26.9 2.2 38.9 5.2 24.5 33.3 33.8 5.5 34.0 20.8 6.8 7.4 13.6 14.0 10.6 6.3 12.1 23.4 28.6 9.1 2.5 6.4 1.5 41.1 35.9 3.8 10.7 28.1 6.7 3.2 39.5 23.3 7.5 14.4 39.9 35.4 20.4 45.1 7.4 10.2 32.5 1.4 23.3 5.5 35.3 1.6 2.9 10.5 4.8 10.6 8.9 51.3 4.4 1.7 1.2 5.1 0.3 0.6 3.0 0.5 0.9 0.8 0.8 0.0 5.6 0.6 13.9 0.6 1.5 26.1 0.4 2.6 1.6 1.1 1.3 0.4 2.9 0.3 1.0 0.0 0.8 0.7 33.8 2.6 3.3 2.7 4.2 1.8 0.6 1.1 0.0 0.6 0.8 0.8 0.3 10.7 3.1 0.5 0.6 0.0 5.7 2.1 2.1 5.0 3.2 0.3 0.5 0.6 7.7 0.1 3.4 0.3 0.9 0.1 0.7 0.7 1.6 0.5 1.0 0.1 3.6 9.3 0.5 0.3 0.2 0.8 0.3 0.1 0.1 0.2 0.2 0.4 0.5 0.4 3.0 0.2 0.3 0.7 0.1 0.0 26.9 38.9 33.3 33.8 23.4 28.6 41.1 35.9 39.5 32.5 35.3 51.3 9.2 0.0 4.5 5.9 2.8 6.8 9.6 10.4 0.6 4.6 32.7 24.4 15.8 17.2 16.5 9.2 4.2 6.2 4.6 18.2 0.0 3.7 5.3 9.4 2.0 7.4 11.4 14.3 5.1 4.9 1.4 2.7 9.7 9.9 7.0 1.7 6.8 3.2 3.1 5.0 7.5 9.6 8.2 2.5 3.3 1.5 1.8 2.9 3.6 12.2 3.9 36.8 7.2 2.0 62.3 5.1 10.1 10.5 2.0 10.5 15.9 1.4 17.8 7.6 6.6 5.7 4.5 16.0 5.7 4.8 9.7 4.5 3.3 1.5 10.5 5.7 ARNT "bHLHe2, HIF-1beta" ENSG00000143437 "Aryl hydrocarbon receptor nuclear translocator" P27540 1 150809713-150876708 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 7 "U-698: 397.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001759, CAB004318" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Nuclear bodies" "CAB004318: AB_626698, HPA001759: AB_1078213" "unprognostic (1.81e-1)" "unprognostic (8.14e-2)" "unprognostic (6.87e-2)" "unprognostic (5.76e-2)" "unprognostic (1.86e-1)" "unprognostic (4.10e-2)" "unprognostic (9.43e-2)" "unprognostic (5.27e-3)" "unprognostic (5.05e-1)" "unprognostic (3.42e-2)" "unprognostic (1.22e-1)" "unprognostic (9.52e-2)" "unprognostic (1.85e-3)" "unprognostic (2.68e-1)" "unprognostic (4.67e-1)" "unprognostic (6.45e-2)" "unprognostic (6.92e-2)" 25.8 20.4 9.6 18.1 9.6 17.1 22.7 16.2 12.2 31.8 16.5 19.5 15.0 27.4 14.8 19.2 25.0 20.5 20.7 8.9 10.7 17.8 42.9 24.7 17.5 10.4 9.5 37.7 28.6 19.6 12.5 31.2 10.2 16.3 21.2 39.1 15.5 17.6 32.3 23.9 17.0 29.0 8.0 19.5 19.0 17.3 10.9 20.4 19.6 28.1 22.4 21.3 24.0 11.2 17.1 17.2 25.6 19.5 53.4 50.9 34.2 19.0 36.9 25.2 22.7 15.1 17.0 18.3 16.5 34.0 12.4 19.1 24.2 21.3 21.9 29.3 13.8 21.4 28.7 17.6 31.0 26.4 24.7 39.9 20.0 30.7 26.9 30.6 31.3 24.4 27.9 34.9 26.3 33.8 21.1 15.0 21.2 30.9 13.0 26.1 30.8 25.5 20.6 17.4 17.6 25.1 36.6 25.3 15.2 34.4 32.6 59.4 22.6 20.9 18.8 16.8 16.8 39.8 30.8 397.5 25.5 0.9 14.4 46.6 23.6 21.2 12.1 21.6 11.1 8.7 10.0 11.7 18.7 8.7 9.5 9.8 11.9 12.0 23.4 7.8 11.1 16.2 9.6 9.6 16.2 12.2 8.9 10.7 10.4 9.5 10.2 8.0 10.9 11.2 14.8 12.8 10.3 28.1 14.9 14.1 9.9 11.0 8.0 23.6 10.2 6.9 12.8 24.3 11.6 11.0 54.2 24.5 12.6 13.3 3.9 11.2 5.0 10.3 23.3 14.8 20.4 16.6 41.6 9.7 37.1 25.4 8.6 20.6 3.8 17.1 30.0 47.7 20.3 6.7 47.5 16.5 8.2 39.1 20.1 4.3 32.3 20.0 10.6 39.4 27.9 7.9 13.4 41.7 50.9 9.6 8.1 32.7 13.0 8.8 10.1 13.1 9.7 38.3 13.1 17.0 19.4 18.4 16.7 11.0 15.3 29.6 12.7 20.7 9.0 10.0 ARPIN "C15orf38, MGC61550" ENSG00000242498 "Actin related protein 2/3 complex inhibitor" Q7Z6K5 15 89895006-89912952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 5.3;intermediate monocyte: 2.9;myeloid DC: 4.5" "Group enriched" "Detected in many" 6 "dendritic cells: 4.5;monocytes: 5.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040513, HPA047173, HPA052278" Uncertain NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA052278: AB_2681783" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.01e-2)" "unprognostic (2.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (2.67e-3)" "unprognostic (1.75e-2)" "unprognostic (1.57e-1)" "prognostic favorable (4.19e-4)" "unprognostic (8.47e-2)" "unprognostic (1.36e-1)" "unprognostic (2.23e-1)" "unprognostic (6.62e-3)" 10.6 4.7 9.3 7.0 10.1 0.9 8.4 11.2 8.5 11.4 5.4 15.0 14.5 11.9 13.9 10.3 11.5 8.1 8.1 8.1 9.7 7.5 5.2 11.9 4.6 10.8 9.3 14.7 40.0 12.9 5.0 8.6 9.7 12.6 16.7 9.5 9.0 11.3 9.5 12.2 16.9 11.5 9.3 7.7 8.0 6.0 10.5 3.3 8.7 8.1 5.4 9.5 10.7 10.4 13.9 18.5 18.6 12.3 10.9 14.9 3.5 12.8 9.5 8.5 9.6 2.6 18.8 0.1 6.3 11.6 3.4 6.4 0.1 12.6 7.6 0.1 4.6 0.1 22.1 3.5 7.2 0.1 1.2 9.7 12.2 10.2 2.1 6.5 14.9 0.1 0.1 0.6 11.1 2.8 0.0 0.3 7.5 11.6 2.1 0.0 0.5 0.1 4.5 13.2 0.6 6.1 28.1 11.4 14.5 9.9 22.4 3.8 10.3 15.8 17.6 20.3 6.4 0.3 0.1 0.2 13.1 0.1 5.9 0.5 5.3 0.1 0.1 2.9 0.3 0.1 0.1 0.0 4.5 0.2 0.1 0.1 0.7 0.2 0.4 0.3 0.0 1.3 9.3 10.1 11.2 8.5 8.1 9.7 10.8 9.3 9.7 9.3 10.5 10.4 14.8 25.6 21.0 0.0 1.0 0.0 16.2 0.0 11.4 9.5 11.1 10.3 10.2 22.8 8.1 16.5 12.5 16.1 0.3 19.0 3.9 10.0 33.3 13.0 11.8 13.2 12.2 1.7 0.0 15.8 17.5 13.6 9.2 10.9 6.3 15.7 13.2 13.4 24.4 5.0 0.0 18.3 0.0 26.6 0.0 109.0 15.2 18.5 0.0 0.0 23.0 14.0 0.0 0.0 0.0 12.8 23.8 17.0 0.2 12.5 50.6 19.2 5.1 15.4 13.1 18.3 11.9 20.2 5.7 18.2 0.0 6.7 0.8 6.4 20.6 12.1 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ARRDC1 MGC40555 ENSG00000197070 "Arrestin domain containing 1" Q8N5I2 9 137605685-137615360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 204.5;T-47d: 89.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044345 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA044345: AB_10965181" "unprognostic (3.25e-2)" "unprognostic (1.41e-2)" "unprognostic (6.03e-3)" "unprognostic (4.32e-3)" "unprognostic (8.21e-2)" "unprognostic (8.01e-2)" "unprognostic (7.95e-2)" "unprognostic (2.65e-2)" "unprognostic (2.37e-1)" "unprognostic (1.26e-1)" "unprognostic (3.55e-1)" "unprognostic (5.52e-2)" "prognostic favorable (3.59e-4)" "unprognostic (5.01e-3)" "unprognostic (1.51e-1)" "unprognostic (8.70e-2)" "unprognostic (1.11e-3)" 19.8 25.2 8.7 9.1 8.8 23.3 28.3 7.4 15.1 23.7 11.4 39.0 22.7 13.1 3.2 60.4 21.5 4.6 23.9 9.4 8.0 35.7 42.9 35.2 11.0 9.3 8.3 10.3 42.9 9.5 30.8 7.8 9.2 43.4 5.3 3.1 51.9 11.2 13.6 37.2 43.8 2.5 8.2 54.6 53.7 21.0 8.5 8.3 31.7 4.0 4.9 23.6 35.9 8.4 39.4 25.4 2.4 8.3 3.9 4.2 38.7 10.2 8.8 5.5 4.2 21.4 53.1 9.5 25.7 7.2 10.5 79.5 2.8 32.9 0.9 8.9 15.6 6.4 23.1 19.4 9.3 11.2 15.4 1.7 49.2 4.9 20.4 7.4 7.9 14.7 13.8 5.6 2.4 204.5 13.6 72.0 5.1 43.9 31.6 16.3 4.2 43.1 20.4 29.2 10.3 7.8 7.1 83.0 11.4 2.5 89.9 26.5 18.8 3.2 4.7 21.8 8.8 11.1 9.0 8.3 8.5 24.9 3.7 108.7 99.2 214.7 35.7 132.5 26.4 23.3 32.7 32.8 121.8 39.9 28.9 28.4 92.9 28.3 122.3 46.1 49.7 56.1 8.7 8.8 7.4 15.1 9.4 8.0 9.3 8.3 9.2 8.2 8.5 8.4 39.4 19.2 22.3 11.1 29.2 17.0 58.5 78.0 29.0 7.2 52.5 35.3 5.4 45.8 67.1 58.8 62.6 85.4 43.1 71.7 37.2 50.2 12.1 30.9 8.2 22.5 17.4 11.1 10.6 46.0 41.8 10.1 85.6 32.9 18.4 22.1 23.2 23.7 48.1 3.3 6.1 56.1 57.0 54.0 29.8 14.8 10.8 41.3 7.2 16.9 57.0 10.7 46.4 2.5 3.5 69.1 72.8 10.5 20.6 58.6 81.6 27.4 53.9 46.0 0.0 4.1 13.7 21.3 13.7 33.7 21.3 73.3 38.8 6.7 47.1 69.0 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 30.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;NK-cells: 42.2;Rod photoreceptor cells: 59.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" NA NA 4400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA023245: AB_1845056, HPA023285: AB_1845057" "unprognostic (3.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-1)" "unprognostic (9.02e-2)" "unprognostic (3.67e-3)" "unprognostic (4.11e-1)" "unprognostic (1.14e-3)" "unprognostic (5.18e-2)" "unprognostic (5.47e-2)" "unprognostic (6.11e-7)" "unprognostic (4.24e-3)" "prognostic favorable (7.04e-4)" "unprognostic (1.87e-2)" "unprognostic (3.68e-2)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" 2.6 4.6 1.5 2.9 2.0 3.4 5.5 6.6 2.0 3.5 8.6 2.2 1.1 3.8 30.2 4.4 6.6 2.1 4.9 1.1 2.9 3.0 2.5 2.4 3.9 2.5 3.6 6.2 2.3 1.2 5.3 2.6 3.6 2.0 1.1 7.8 3.3 5.5 3.7 4.5 1.9 2.1 0.7 4.9 2.6 2.1 2.1 2.5 7.5 3.0 3.6 2.0 2.0 1.4 1.4 1.7 1.3 2.1 7.0 4.3 5.7 1.9 5.7 2.7 1.3 0.7 3.2 3.3 4.8 2.5 1.1 0.2 2.2 0.7 1.0 4.8 2.0 1.8 1.8 5.4 5.7 5.1 3.6 1.6 1.3 0.7 2.8 7.2 3.1 5.0 1.0 9.5 1.2 6.2 5.9 4.1 2.0 0.6 1.6 0.2 1.0 8.8 4.1 0.9 7.0 0.6 2.3 5.5 12.1 2.7 13.5 6.1 3.3 4.2 0.4 1.6 0.7 10.5 5.8 5.0 3.3 6.4 1.6 7.1 8.5 6.5 6.3 6.1 4.4 4.0 4.2 6.0 7.7 2.2 4.2 6.0 12.8 4.3 5.2 1.2 4.7 5.4 1.5 2.0 6.6 2.0 1.1 2.9 2.5 3.6 3.6 0.7 2.1 1.4 4.9 3.2 2.7 11.8 7.7 4.0 5.0 4.7 0.0 23.8 9.2 3.8 2.7 8.6 4.8 12.9 54.2 8.1 11.2 3.6 9.8 3.2 0.4 8.7 9.2 8.6 1.8 5.3 18.8 4.7 23.8 24.3 2.6 11.7 3.8 6.4 17.5 3.0 9.2 26.9 26.0 5.2 0.0 6.9 10.7 1.3 13.4 8.4 23.2 12.2 16.0 9.4 42.2 7.1 2.7 2.3 10.9 23.0 11.1 10.0 2.4 12.8 4.3 59.6 6.6 8.7 5.5 1.4 3.6 6.0 3.8 16.8 13.6 9.3 2.3 8.8 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASB2 ASB-2 ENSG00000100628 "Ankyrin repeat and SOCS box containing 2" Q96Q27 14 93934166-93976739 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 522.2;tongue: 157.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.1;Early spermatids: 26.4;Late spermatids: 29.9;Skeletal myocytes: 27.6;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 7 "eosinophil: 50.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 50.8" "Cell line enhanced" "Detected in some" "Karpas-707: 12.8;RPMI-8226: 12.4;SK-MEL-30: 5.9;U-266/70: 42.1;U-266/84: 8.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001546 Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA001546: AB_1078224" "unprognostic (5.65e-4)" "unprognostic (8.19e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.62e-6)" "unprognostic (4.11e-2)" "unprognostic (1.61e-1)" "unprognostic (5.29e-2)" "unprognostic (1.05e-3)" "unprognostic (4.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (2.49e-7)" "unprognostic (2.51e-3)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.27e-1)" 2.9 0.8 0.8 5.6 2.1 0.5 1.5 0.0 1.9 12.0 0.0 66.5 4.0 31.6 0.3 4.0 26.6 0.5 78.5 0.6 0.0 0.5 0.5 3.0 7.4 0.1 0.0 2.9 0.3 0.2 0.2 0.2 0.3 14.4 0.4 0.0 6.6 0.9 522.2 2.3 18.3 1.6 0.0 4.2 17.2 0.4 0.3 0.4 1.2 157.6 3.2 30.4 8.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.4 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.1 0.0 12.4 0.0 0.2 0.1 0.0 0.0 0.0 5.9 0.0 0.0 2.9 0.0 0.0 0.0 0.2 0.0 42.1 8.6 1.7 0.5 2.6 0.5 0.0 0.2 50.8 1.9 2.7 0.3 1.9 1.7 3.8 4.2 0.4 0.2 0.5 0.1 0.0 7.8 0.4 2.3 1.3 0.8 2.1 0.0 1.9 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.0 0.3 3.3 0.4 0.1 8.4 0.0 0.2 0.2 0.9 51.1 0.0 2.9 0.0 0.0 0.1 3.0 0.0 0.0 1.4 26.4 1.7 0.3 0.5 0.0 2.7 4.7 0.0 0.5 1.9 1.1 2.5 0.0 0.0 0.0 0.0 0.6 0.0 1.9 0.0 0.0 0.0 0.3 29.9 0.3 5.3 1.8 1.9 5.8 0.8 2.1 0.0 0.7 0.2 0.0 0.4 10.7 0.1 0.0 0.0 0.4 1.1 0.0 27.6 5.0 0.8 8.4 0.1 0.1 2.9 14.5 0.1 0.1 0.3 ATAD1 "FLJ14600, Msp1" ENSG00000138138 "ATPase family AAA domain containing 1" Q8NBU5 10 87751512-87841361 "Disease related genes, Human disease related genes, Predicted membrane proteins" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 16 "Early spermatids: 987.5;Late spermatids: 1846.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037569 Uncertain Approved "Nucleoli rim,Mitochondria" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoli rim" Mitochondria "HPA037569: AB_10672496" "unprognostic (9.92e-2)" "unprognostic (2.90e-1)" "unprognostic (4.05e-2)" "unprognostic (2.68e-1)" "unprognostic (3.24e-2)" "unprognostic (6.60e-3)" "unprognostic (3.38e-1)" "unprognostic (1.40e-1)" "unprognostic (2.35e-1)" "unprognostic (8.45e-2)" "unprognostic (1.35e-3)" "unprognostic (1.67e-2)" "prognostic favorable (3.98e-6)" "unprognostic (2.35e-1)" "unprognostic (3.29e-1)" "unprognostic (3.45e-2)" "unprognostic (4.22e-2)" 15.7 17.4 9.9 9.0 10.3 4.9 16.3 11.3 12.6 16.0 10.7 18.2 10.9 16.8 13.7 16.2 13.8 10.5 36.1 10.4 11.5 16.7 18.0 14.5 11.8 10.7 11.5 15.9 12.7 28.5 13.4 15.2 11.1 18.7 14.5 28.0 14.9 16.1 37.2 15.1 12.5 13.6 10.0 10.0 13.6 26.4 11.0 13.8 17.4 31.8 12.1 15.5 16.0 10.2 18.8 18.2 20.8 18.2 27.4 29.5 14.4 19.7 33.4 19.6 20.6 14.6 53.8 17.6 15.4 17.3 9.8 31.3 18.9 14.4 21.2 18.6 26.4 15.3 24.0 18.8 30.5 41.7 8.0 23.0 45.4 20.7 42.1 37.2 12.7 14.1 15.9 20.7 22.7 11.2 23.1 22.9 16.4 13.9 10.0 15.8 13.2 19.2 28.9 13.4 14.2 31.5 20.3 12.3 32.0 21.0 29.1 18.0 19.3 16.2 13.9 11.2 24.5 25.4 39.4 22.5 20.8 23.7 11.5 8.4 2.8 4.9 6.3 4.9 10.3 7.2 7.3 8.3 5.4 5.7 9.1 8.6 1.7 8.6 6.9 4.6 7.6 5.7 9.9 10.3 11.3 12.6 10.4 11.5 10.7 11.5 11.1 10.0 11.0 10.2 31.0 54.5 28.0 46.4 41.4 26.8 42.9 46.2 44.3 50.4 29.8 20.8 81.3 27.1 44.9 22.0 35.5 37.7 35.2 33.8 23.5 37.0 987.5 22.3 38.3 21.7 22.8 24.6 69.0 28.0 33.2 35.6 32.6 28.7 29.2 23.1 20.0 28.9 27.3 70.7 73.1 22.9 50.8 18.0 20.1 1846.8 35.8 25.1 32.0 37.5 16.1 59.6 23.7 58.8 52.7 39.0 25.2 47.0 32.3 42.3 20.5 29.5 44.8 54.8 59.2 29.5 43.8 77.2 29.8 34.6 30.1 88.4 40.0 34.8 23.7 54.6 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ATP10B "ATPVB, FLJ21477, KIAA0715" ENSG00000118322 "ATPase phospholipid transporting 10B (putative)" O94823 5 160563120-160852214 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.1;gallbladder: 16.6;intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 136.4;Oligodendrocyte precursor cells: 293.0;Oligodendrocytes: 419.4;Undifferentiated cells: 90.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034574 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA034574: AB_10669992" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (4.47e-4)" "unprognostic (3.99e-2)" "unprognostic (6.10e-3)" "unprognostic (4.69e-2)" "unprognostic (4.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.20e-2)" "unprognostic (3.42e-2)" "unprognostic (5.12e-2)" "unprognostic (2.38e-3)" "unprognostic (5.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.38e-1)" "unprognostic (2.14e-1)" 0.1 0.0 4.1 5.0 9.0 0.0 0.4 8.8 6.4 1.0 0.1 44.5 24.7 0.0 12.3 6.2 0.4 16.6 0.0 4.3 5.0 0.1 0.0 0.0 0.0 10.6 7.8 0.0 2.9 0.0 0.0 0.0 9.9 0.0 45.7 0.0 1.8 0.7 0.0 7.1 21.0 1.5 5.8 0.0 4.8 0.3 8.0 5.0 0.0 0.0 2.9 1.5 2.5 17.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 9.0 8.8 6.4 4.3 5.0 10.6 7.8 9.9 5.8 8.0 17.1 0.1 0.0 0.0 42.7 0.6 0.4 0.1 12.9 0.0 0.0 0.1 0.0 1.2 21.5 15.1 1.8 0.0 0.0 0.0 136.4 0.0 23.6 0.2 0.2 0.0 0.3 13.2 0.0 4.0 20.3 0.1 0.0 10.7 0.3 0.0 0.0 0.0 0.3 0.1 0.0 3.9 55.4 4.1 0.0 1.2 0.6 0.0 0.1 1.8 1.9 1.6 0.0 0.0 293.0 419.4 16.4 64.7 0.0 0.4 0.1 24.1 0.0 16.0 0.0 0.0 0.0 0.6 0.0 0.1 2.9 0.9 0.5 0.3 0.0 90.7 6.5 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2590.4;tongue: 3205.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 821.1;Distal tubular cells: 1238.5;Extravillous trophoblasts: 592.7;Hofbauer cells: 608.9;Proximal tubular cells: 951.7;Syncytiotrophoblasts: 1138.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 19000000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB017527: AB_1121153, HPA001520: AB_1078243, HPA001528: AB_1078242" "prognostic unfavorable (7.17e-6)" "unprognostic (5.69e-2)" "unprognostic (1.08e-2)" "unprognostic (7.24e-2)" "unprognostic (8.39e-2)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.92e-2)" "unprognostic (8.19e-3)" "unprognostic (2.38e-2)" "unprognostic (1.44e-2)" "unprognostic (2.11e-2)" "prognostic favorable (1.43e-9)" "unprognostic (2.79e-1)" "unprognostic (3.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.30e-2)" 432.7 555.5 217.6 300.5 231.4 465.8 301.5 281.6 303.8 241.8 443.3 741.6 689.5 235.4 223.4 527.6 277.9 225.7 2011.6 233.0 307.1 945.9 609.3 253.4 294.6 264.2 242.9 200.2 301.7 1311.6 252.6 301.4 280.4 280.9 767.6 484.2 407.7 356.4 2590.4 398.6 575.5 332.5 230.9 272.5 494.9 236.0 277.5 390.9 342.8 3205.3 458.3 404.1 311.2 244.7 693.6 834.9 632.3 1003.6 578.3 596.7 1159.8 683.2 645.6 1179.1 663.9 1375.7 755.6 1236.3 723.0 863.5 482.9 906.1 1378.1 851.5 1039.4 579.9 987.5 1333.1 726.4 872.5 716.6 1509.7 912.9 755.1 843.3 918.0 1171.2 870.2 985.8 901.7 1246.3 1363.1 992.2 671.5 1134.4 941.3 1085.9 905.6 1637.6 1079.3 711.0 1603.5 1315.6 1196.7 737.5 658.2 1042.3 1481.3 1214.0 663.4 1404.1 1151.8 657.6 454.8 507.9 671.9 751.0 659.5 865.7 1254.8 684.7 1007.8 718.4 403.5 549.4 281.8 293.5 643.6 326.3 303.2 275.4 313.6 713.4 248.4 221.0 266.8 137.1 296.9 750.6 360.9 372.9 1077.1 217.6 231.4 281.6 303.8 233.0 307.1 264.2 242.9 280.4 230.9 277.5 244.7 172.3 134.6 173.2 0.0 48.6 0.0 0.0 0.0 0.0 0.0 176.8 149.1 0.0 0.0 81.1 277.7 0.0 821.1 141.5 0.0 1238.5 517.7 0.0 194.1 169.2 115.7 0.0 0.0 0.0 367.9 592.7 115.0 0.0 163.3 145.1 267.6 0.0 0.0 608.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 281.2 0.0 0.0 0.0 0.0 333.3 0.0 0.0 26.8 0.0 0.0 951.7 102.7 0.0 0.0 0.0 151.1 0.0 0.0 0.0 0.0 1138.6 77.4 518.4 0.0 0.0 ATP5F1E ATP5E ENSG00000124172 "ATP synthase F1 subunit epsilon" P56381 20 59025475-59032345 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 3414.2;Hofbauer cells: 2765.4;Proximal tubular cells: 4125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.73e-1)" "unprognostic (6.30e-2)" "unprognostic (8.16e-2)" "unprognostic (9.04e-2)" "unprognostic (2.16e-1)" "unprognostic (1.92e-3)" "unprognostic (7.88e-3)" "unprognostic (2.51e-1)" "unprognostic (5.01e-2)" "unprognostic (6.41e-2)" "unprognostic (4.35e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.82e-4)" "unprognostic (3.98e-1)" "unprognostic (3.21e-1)" "unprognostic (1.67e-1)" "unprognostic (2.44e-2)" 81.4 88.3 92.2 98.5 94.5 125.6 62.3 95.3 135.8 49.3 95.7 77.2 80.1 51.2 25.3 77.0 45.2 13.9 162.8 92.7 95.7 128.5 80.2 69.3 69.8 94.2 94.0 42.1 44.9 52.9 104.8 34.0 94.4 50.6 33.1 42.8 62.7 23.7 240.1 42.8 78.9 25.6 95.4 93.5 69.5 47.7 93.7 64.7 64.1 107.0 40.0 63.4 55.5 97.1 150.0 49.6 98.1 90.0 94.0 87.2 65.2 155.9 60.6 102.2 66.0 156.3 143.5 81.1 184.7 82.7 159.6 141.5 70.3 123.7 67.0 66.7 76.4 271.4 107.2 136.5 86.4 193.2 234.6 95.0 105.3 62.5 77.8 99.8 76.9 107.6 103.6 113.8 59.4 144.4 247.8 299.1 32.9 220.4 203.4 120.2 138.3 156.8 107.5 83.0 98.0 146.6 261.6 273.9 328.4 83.5 182.5 312.8 264.3 208.3 222.0 138.9 213.7 180.2 245.9 238.1 201.5 117.9 117.1 613.1 420.6 757.3 237.5 463.8 224.9 351.4 285.8 268.7 356.0 291.7 227.8 259.4 713.9 243.1 470.7 601.7 393.3 781.7 92.2 94.5 95.3 135.8 92.7 95.7 94.2 94.0 94.4 95.4 93.7 97.1 1036.3 516.0 530.8 0.0 331.5 0.0 0.0 0.0 0.0 0.0 1042.4 1138.3 0.0 0.0 289.7 1121.9 0.0 705.8 812.6 0.0 3414.2 998.0 0.0 1145.2 1007.1 436.6 0.0 0.0 0.0 1202.6 956.9 341.7 0.0 1410.3 352.0 594.0 0.0 0.0 2765.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 998.4 0.0 0.0 1473.1 0.0 0.0 0.0 0.0 1427.7 0.0 0.0 132.5 0.0 0.0 4125.3 392.8 0.0 0.0 0.0 334.0 0.0 0.0 0.0 0.0 590.5 431.2 731.9 0.0 0.0 ATP5PD "ATP5H, ATP5JD, ATPQ" ENSG00000167863 "ATP synthase peripheral stalk subunit d" O75947 17 75038863-75046985 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1142.6;Hofbauer cells: 465.0;Proximal tubular cells: 1059.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042777, HPA048459" Enhanced Supported Mitochondria NA NA 60000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042777: AB_2678160, HPA048459: AB_2680402" "unprognostic (1.37e-1)" "unprognostic (4.41e-2)" "unprognostic (1.70e-3)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "unprognostic (4.81e-2)" "unprognostic (7.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (2.72e-1)" "unprognostic (8.72e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.73e-1)" "unprognostic (4.29e-2)" 253.8 271.0 253.5 156.0 260.5 187.2 228.8 270.5 385.7 190.7 282.9 337.1 295.1 170.7 279.9 355.9 173.5 140.1 985.5 261.9 271.1 465.2 454.2 174.0 166.0 264.8 256.9 147.5 222.2 427.1 203.9 174.1 260.8 177.9 323.6 256.0 240.8 200.5 1102.8 264.7 257.4 211.3 260.2 155.0 307.4 93.8 262.3 175.2 263.7 1025.5 221.2 230.3 221.5 261.7 522.8 445.4 335.6 439.8 532.6 647.4 449.1 437.2 571.3 478.5 452.2 351.8 397.1 349.8 282.5 550.2 450.2 462.2 409.0 571.6 637.5 171.6 346.0 359.1 340.2 703.1 524.2 463.5 225.8 555.3 444.8 390.7 552.7 380.9 646.8 268.5 380.1 462.6 595.1 503.3 461.8 515.6 257.1 1185.3 626.9 322.3 970.4 652.3 1007.3 499.7 335.8 368.5 515.5 811.0 730.7 496.9 805.1 463.2 337.4 591.1 413.2 520.0 520.4 369.0 315.5 360.8 530.2 455.4 390.3 410.8 440.7 481.0 274.8 540.9 320.8 364.5 467.5 341.7 509.7 292.8 416.1 388.9 253.0 301.6 458.0 453.6 492.8 495.9 253.5 260.5 270.5 385.7 261.9 271.1 264.8 256.9 260.8 260.2 262.3 261.7 173.8 173.1 156.4 0.0 35.0 0.0 0.0 0.0 0.0 0.0 159.6 234.2 0.0 0.0 102.8 259.3 0.0 384.3 74.0 0.0 1142.6 313.6 0.0 188.2 153.6 70.4 0.0 0.0 0.0 379.5 328.4 82.7 0.0 207.6 88.3 84.6 0.0 0.0 465.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 125.1 0.0 0.0 208.8 0.0 0.0 0.0 0.0 284.3 0.0 0.0 13.8 0.0 0.0 1059.2 101.3 0.0 0.0 0.0 88.3 0.0 0.0 0.0 0.0 336.3 54.4 155.9 0.0 0.0 AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 24.1;Hepatocytes: 62.7;Sertoli cells: 78.9;Smooth muscle cells: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ASC diff: 5.6;Karpas-707: 13.1;U-266/84: 9.8" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" 17.2 56.6 0.4 1.4 0.2 0.0 9.0 0.0 0.3 9.1 1.4 1.7 0.7 10.9 1.1 3.0 4.8 6.1 2.0 0.3 0.5 4.6 20.9 0.5 1.2 0.5 0.2 1.3 2.3 2.2 0.5 0.3 0.2 2.3 1.2 1.4 1.1 4.2 2.0 1.8 0.9 12.2 0.1 0.8 1.7 0.6 0.8 1.4 10.4 3.5 0.6 2.5 2.6 0.2 0.1 0.2 0.6 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.3 0.3 0.5 0.5 0.2 0.2 0.1 0.8 0.2 14.1 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.6 0.3 0.2 0.3 3.4 1.5 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.4 3.1 24.1 4.5 0.0 2.7 0.1 0.0 0.5 2.7 0.5 1.6 0.0 0.2 0.7 62.7 0.2 0.0 1.0 0.0 0.0 1.3 0.3 0.0 2.8 1.4 0.0 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 78.9 2.9 100.9 0.2 0.2 0.0 0.3 0.1 0.6 2.1 0.0 0.3 AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1" "Group enriched" "Detected in some" 4 "Adipocytes: 48.0;Collecting duct cells: 49.7;Endothelial cells: 17.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 7 "cerebellum: 3.9" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.6;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 29 "monocytes: 3.6" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;SCLC-21H: 3.7;U-266/84: 3.7;U-698: 3.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "cerebellum: 6.8" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 16: U-266 - Nucleosome" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" 5.2 0.2 0.1 0.2 0.0 0.8 3.1 3.9 0.1 1.0 0.5 0.8 0.6 0.9 0.1 0.6 1.6 1.0 5.1 0.1 0.0 8.1 0.0 1.3 1.0 0.3 0.5 0.2 0.6 0.7 0.1 0.2 0.4 0.7 0.2 0.0 0.7 0.6 3.1 1.5 0.8 0.8 0.1 0.3 0.7 0.2 0.1 0.4 0.9 4.0 0.3 0.8 1.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.6 3.2 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.1 1.2 0.6 0.0 0.0 1.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.8 1.0 0.1 0.0 0.0 1.4 0.6 1.4 0.0 0.0 3.7 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.6 3.7 3.6 0.0 0.9 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.1 0.0 3.9 0.1 0.1 0.0 0.3 0.5 0.4 0.1 0.1 0.2 48.0 3.2 1.3 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.5 0.4 1.5 0.0 0.0 49.7 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 8.6 0.8 0.0 0.0 0.1 1.3 0.0 0.1 0.5 0.0 0.1 B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 196.4;Intestinal goblet cells: 47.4;Paneth cells: 72.5;Proximal enterocytes: 94.1;Undifferentiated cells: 57.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 23.5;RPTEC TERT1: 27.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.6" "HPA054092, HPA054684" Approved "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" 0.0 0.3 2.5 0.9 8.6 0.0 2.6 0.7 3.7 2.2 1.9 22.4 27.3 0.7 1.3 1.6 1.3 5.5 0.0 2.4 4.6 0.2 0.1 0.1 0.0 2.0 2.1 0.3 3.3 0.0 1.8 0.0 1.3 0.4 37.4 0.8 4.5 0.1 0.0 0.8 33.7 0.8 1.3 0.0 5.0 0.4 6.9 1.0 1.2 0.3 2.0 1.3 2.3 0.7 0.0 0.9 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 23.5 0.0 0.2 0.2 2.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 6.3 0.2 0.6 0.0 2.7 0.1 27.1 1.7 4.6 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.7 0.2 1.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 8.6 0.7 3.7 2.4 4.6 2.0 2.1 1.3 1.3 6.9 0.7 0.1 0.0 0.0 6.5 0.3 0.0 0.5 0.1 0.0 7.4 8.0 8.1 2.2 10.0 5.3 5.5 0.0 0.0 0.2 196.4 0.0 7.5 0.4 0.2 5.9 0.4 28.9 0.0 3.6 4.7 0.0 0.2 13.3 0.2 4.5 0.8 0.0 0.0 0.0 0.0 4.8 47.4 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 1.4 0.0 11.1 1.0 9.2 72.5 0.0 0.0 0.6 94.1 0.1 1.5 0.2 0.0 0.1 0.4 0.1 1.7 0.5 0.0 0.0 0.5 0.0 57.7 9.7 B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623409-57633239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 61.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.0;Excitatory neurons: 22.0;Horizontal cells: 21.9;Inhibitory neurons: 13.4;Smooth muscle cells: 7.5" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" NA NA 35000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" 1.9 1.1 26.9 1.9 29.7 0.0 0.7 29.3 61.1 1.3 0.6 2.7 0.5 2.1 2.7 0.7 0.7 1.1 3.3 34.9 21.9 0.8 0.4 0.6 0.6 16.7 11.8 0.3 0.3 0.3 1.7 0.4 20.5 2.6 1.2 4.2 1.8 5.0 9.5 0.6 1.2 2.5 8.1 0.6 0.9 0.7 19.1 0.3 1.2 7.2 1.0 1.2 1.6 29.9 7.5 38.2 18.2 38.7 0.3 0.1 0.4 3.0 11.3 19.0 17.5 2.8 21.9 3.0 47.9 13.2 35.9 3.3 15.3 2.1 5.2 67.4 2.6 1.8 10.1 9.9 0.4 3.1 4.1 0.1 0.9 11.0 0.5 6.7 0.2 11.4 8.7 34.8 2.4 13.5 2.5 0.1 13.0 0.9 7.7 0.1 27.1 8.0 0.1 0.1 34.9 12.3 3.1 1.1 0.4 0.9 7.0 3.3 0.0 22.8 28.1 24.0 26.1 37.0 34.0 2.6 28.9 2.3 45.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 26.9 29.7 29.3 61.1 34.9 21.9 16.7 11.8 20.5 8.1 19.1 29.9 0.8 0.0 0.0 2.6 0.0 0.4 0.0 0.0 0.0 10.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.8 0.0 0.0 22.0 0.2 0.2 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 21.9 13.4 0.0 0.0 0.0 0.3 0.7 2.8 0.1 3.6 2.8 2.6 0.7 0.0 4.5 2.7 0.5 0.0 3.0 0.0 0.1 0.0 0.2 0.0 2.6 6.6 0.6 7.5 1.6 4.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Distal enterocytes: 3.9;Glandular and luminal cells: 5.2;Intestinal goblet cells: 11.5;Ionocytes: 4.1;Proximal enterocytes: 14.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 9: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" 1.2 1.3 1.4 7.8 1.0 4.7 0.7 6.6 2.1 0.2 2.3 33.5 2.1 1.1 0.6 0.7 0.4 2.2 1.0 1.7 0.8 9.1 0.9 1.4 2.2 0.7 0.4 1.0 1.7 0.1 0.0 0.7 0.5 0.7 14.2 7.5 2.0 0.3 0.8 2.8 8.4 2.7 0.0 2.2 5.9 1.5 1.1 0.2 5.9 0.1 0.8 0.6 0.0 1.5 0.9 1.7 1.7 3.0 0.1 0.0 0.9 1.3 1.0 0.0 0.1 4.0 1.4 2.1 2.1 0.0 0.6 0.9 0.7 0.1 0.2 1.8 1.8 2.2 5.1 2.1 0.0 1.1 3.5 0.2 1.4 0.3 0.2 0.7 0.0 1.6 1.3 3.3 0.0 1.1 1.4 1.5 2.1 0.3 0.8 2.5 0.7 0.6 5.4 1.4 1.4 1.5 0.6 0.7 0.6 1.7 1.8 1.4 0.6 2.2 1.3 1.3 0.7 2.6 0.9 2.3 0.7 1.4 0.9 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 1.4 1.0 6.6 2.1 1.7 0.8 0.7 0.4 0.5 0.0 1.1 1.5 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.3 0.5 0.0 0.9 5.5 0.0 0.0 0.0 3.9 1.9 0.6 0.7 0.6 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.5 4.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 14.8 0.1 0.8 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.0 0.1 0.0 2.1 0.1 B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, iGNT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 220.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.3;Horizontal cells: 158.2;Muller glia cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" NA NA 57000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" 16.6 41.4 120.6 6.1 124.9 1.3 16.0 71.0 125.2 23.1 68.7 30.1 16.2 28.5 15.2 8.3 23.4 9.9 44.6 115.3 220.2 25.3 18.8 17.3 6.7 85.9 97.3 34.3 25.5 22.6 62.3 22.5 101.0 17.3 7.7 46.0 15.8 22.4 27.7 12.1 14.6 14.0 91.9 10.2 25.8 8.2 150.4 6.5 21.0 19.2 4.3 20.2 16.3 83.9 10.8 26.7 29.7 36.5 32.6 29.3 39.4 18.4 42.5 28.1 22.9 20.1 14.9 8.9 76.1 16.9 24.1 16.8 32.0 20.6 13.5 17.6 58.2 1.3 20.4 77.6 19.3 7.0 2.7 28.6 15.6 17.5 7.4 92.8 33.5 14.8 8.6 13.7 13.6 18.1 16.7 19.1 20.2 10.6 28.0 24.0 23.2 15.9 29.6 2.7 17.8 33.7 15.8 10.4 74.8 18.4 42.6 6.8 19.7 21.8 15.9 28.0 9.6 26.1 19.2 5.3 36.8 5.8 26.0 0.0 1.2 0.0 7.1 0.4 9.9 5.7 7.8 7.6 3.0 3.2 9.0 8.3 0.4 4.6 0.3 7.4 5.7 4.4 120.6 124.9 71.0 125.2 115.3 220.2 85.9 97.3 101.0 91.9 150.4 83.9 13.5 22.4 10.8 25.8 2.9 0.0 1.6 0.0 14.2 72.3 6.2 12.7 45.9 25.8 1.8 20.2 58.4 57.8 8.6 8.0 5.9 7.4 0.5 3.9 9.7 17.1 4.9 0.8 22.1 6.0 22.6 23.4 6.6 2.6 1.3 22.5 30.4 24.4 12.7 158.2 35.0 8.0 0.0 2.4 0.0 2.4 32.6 2.6 0.0 10.3 1.3 70.1 2.1 22.6 14.2 4.3 4.9 40.6 6.1 2.0 13.3 17.5 2.9 47.4 26.3 21.2 11.8 1.4 2.8 5.8 0.0 18.1 2.6 28.0 7.2 0.3 BATF "B-ATF, BATF1, SFA-2" ENSG00000156127 "Basic leucine zipper ATF-like transcription factor" Q16520 14 75522455-75546993 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.7;lymphoid tissue: 30.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 105.4;Breast myoepithelial cells: 73.9;granulocytes: 243.7;NK-cells: 103.0;T-cells: 116.5;Urothelial cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 5 "T-cells: 130.3" "Cell line enhanced" "Detected in many" "HDLM-2: 368.9;MCF7: 134.7;RT4: 83.3;SK-BR-3: 64.8;U-937: 101.6" "Not detected" "Not detected" "HPA059588, HPA064962" Approved Enhanced Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA059588: AB_2684074, HPA064962: AB_2685392" "unprognostic (3.33e-3)" "unprognostic (4.87e-3)" "prognostic unfavorable (8.30e-4)" "prognostic favorable (5.35e-6)" "unprognostic (3.02e-2)" "prognostic favorable (7.91e-5)" "unprognostic (1.14e-2)" "unprognostic (1.39e-1)" "unprognostic (2.94e-1)" "unprognostic (6.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (3.74e-9)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "prognostic favorable (4.30e-4)" 5.5 1.3 1.0 20.5 1.8 21.7 7.8 1.0 1.4 2.2 1.1 3.0 2.6 1.3 1.1 2.9 1.9 5.8 2.4 1.0 1.2 1.4 2.9 8.0 30.6 1.5 1.4 0.5 0.9 8.0 0.5 4.1 1.7 5.5 1.4 0.0 6.5 1.8 0.4 2.9 9.7 2.3 1.2 26.9 7.8 0.6 2.2 7.2 1.9 1.0 20.4 18.2 2.9 1.5 4.7 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 368.9 0.0 7.5 0.0 1.6 11.5 10.0 36.3 0.1 0.0 0.0 0.0 0.0 0.0 8.1 2.0 10.3 0.0 134.7 4.7 30.8 0.2 54.9 0.0 1.1 0.0 6.3 0.0 83.3 0.1 0.0 0.0 64.8 2.7 0.0 6.1 18.7 0.0 0.0 0.0 4.4 0.3 32.8 36.9 0.3 0.0 101.6 0.1 3.6 25.5 8.2 55.0 13.7 43.4 21.3 59.7 74.2 25.2 17.5 23.1 50.4 14.4 21.3 13.2 2.9 130.3 27.8 1.0 1.8 1.0 1.4 1.0 1.2 1.5 1.4 1.7 1.2 2.2 1.5 2.9 9.6 29.3 0.0 17.1 5.4 50.8 5.7 0.6 0.0 105.4 73.9 0.3 1.5 13.5 3.7 0.0 0.4 36.9 0.0 0.0 0.8 0.5 0.9 0.6 5.0 0.0 7.2 0.2 2.5 0.4 4.4 10.2 1.9 243.7 0.0 2.5 0.7 61.3 0.0 0.1 0.0 34.6 15.4 10.7 0.6 0.0 21.7 5.4 1.0 16.7 0.0 103.0 0.0 0.1 11.0 0.1 0.0 29.9 22.1 0.0 0.2 12.8 0.0 0.0 1.0 2.0 0.0 0.1 0.4 3.4 1.1 116.5 0.2 0.5 74.3 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.6" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 158.7;Collecting duct cells: 86.5;Ductal cells: 98.5;Fibroblasts: 79.6;Microglial cells: 165.8;Proximal tubular cells: 148.2" "Group enriched" "Detected in all" 4 "pancreatic cancer: 9.2;renal cancer: 25.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 59.1;BJ hTERT+: 61.4;CACO-2: 93.1;RPTEC TERT1: 140.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" Cytosol Centrosome "HPA070797: " "unprognostic (1.27e-1)" "unprognostic (1.57e-3)" "unprognostic (3.61e-1)" "unprognostic (1.96e-1)" "unprognostic (6.09e-3)" "unprognostic (1.72e-1)" "unprognostic (9.98e-3)" "unprognostic (1.79e-2)" "unprognostic (6.69e-2)" "unprognostic (4.56e-2)" "unprognostic (4.40e-3)" "unprognostic (7.16e-2)" "unprognostic (6.44e-2)" "unprognostic (1.37e-3)" "unprognostic (4.19e-2)" "unprognostic (6.23e-2)" "unprognostic (2.94e-2)" 10.6 6.1 0.3 4.0 0.5 0.3 8.7 0.0 1.6 5.8 1.9 4.5 1.2 4.9 4.0 3.5 7.5 11.6 10.5 0.6 1.0 28.6 2.4 5.8 2.4 1.2 0.6 13.9 16.9 0.8 3.6 3.6 0.2 3.8 4.1 1.4 4.3 4.2 7.6 6.1 2.7 4.7 1.2 2.9 2.7 3.1 0.7 1.4 4.6 6.2 2.7 5.5 5.6 0.7 0.0 59.1 0.8 0.0 17.9 23.0 0.0 38.5 61.4 34.4 40.4 93.1 12.3 0.0 39.8 39.3 8.8 0.8 6.1 7.0 47.4 0.1 5.9 0.0 7.4 0.1 11.5 0.0 0.0 36.0 2.2 26.9 28.6 42.3 0.1 0.0 0.0 0.2 13.4 0.1 0.0 0.0 0.5 0.0 3.8 0.0 14.3 0.0 140.8 7.1 0.2 7.3 0.1 0.4 3.4 2.4 0.0 0.6 0.0 8.2 7.7 1.4 5.0 0.0 0.0 0.1 23.8 0.0 7.8 6.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.5 0.1 0.0 0.3 0.5 0.0 1.6 0.6 1.0 1.2 0.6 0.2 1.2 0.7 0.7 4.1 0.0 0.5 120.5 1.5 7.1 1.3 1.3 0.6 0.6 1.1 4.3 3.3 158.7 1.7 86.5 0.0 0.4 0.1 0.3 78.2 98.5 5.2 43.8 14.4 1.4 3.6 0.0 70.4 3.5 0.2 79.6 0.5 7.2 0.0 4.2 3.3 1.4 3.5 0.0 37.2 1.2 0.0 0.6 18.5 3.2 71.1 1.7 21.4 165.8 1.1 10.1 0.0 25.6 2.7 35.3 1.2 50.0 0.3 2.4 0.0 148.2 14.1 0.2 6.6 40.0 9.8 0.1 3.9 0.3 4.7 4.1 1.5 8.7 1.6 0.1 BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 329.3;Club cells: 215.6;Ionocytes: 443.5;Paneth cells: 140.5;Respiratory ciliated cells: 204.1;Urothelial cells: 175.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 72.9;plasmacytoid DC: 58.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 89.9;CAPAN-2: 44.3;Daudi: 44.2;U-698: 172.1" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051360: AB_2681453" "unprognostic (1.18e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.86e-3)" "unprognostic (3.27e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.45e-5)" "unprognostic (1.38e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (3.04e-1)" 0.2 2.3 0.2 4.1 0.4 4.1 4.9 0.7 0.3 2.8 0.0 8.5 3.6 0.2 1.2 11.3 3.0 3.1 0.3 0.5 0.0 3.8 0.5 1.4 11.6 0.0 0.0 0.3 2.5 1.6 1.0 0.1 0.1 11.4 5.2 0.2 17.5 0.5 0.0 3.5 5.3 0.2 0.0 2.9 13.4 2.0 0.1 1.4 1.8 0.1 11.2 2.6 6.5 0.0 89.9 0.7 0.2 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 28.8 44.3 44.2 4.2 0.0 0.9 19.5 4.8 1.9 0.0 0.7 6.7 0.1 0.6 4.9 0.7 21.2 4.1 0.0 8.8 0.0 0.0 0.3 0.2 9.5 0.3 2.0 0.0 22.9 16.9 28.9 6.7 24.2 7.3 0.2 0.1 20.6 0.9 2.6 1.7 0.0 3.1 8.2 6.5 3.1 1.6 28.9 0.8 0.1 2.4 0.2 1.0 10.4 17.1 172.1 0.0 2.2 0.2 1.8 2.9 72.9 2.7 0.7 4.3 17.1 9.5 4.2 10.4 11.7 6.4 3.5 11.3 0.9 0.8 58.6 7.1 6.3 0.2 0.4 0.7 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 4.2 0.0 9.3 12.6 32.7 329.3 3.4 0.0 39.7 24.1 0.7 17.2 215.6 7.3 0.0 1.4 7.9 43.0 7.9 62.2 0.3 17.7 0.8 2.3 50.6 5.7 0.3 16.2 1.2 0.9 90.7 9.1 0.0 0.1 5.3 0.7 0.9 0.0 0.2 52.9 443.5 1.4 4.8 0.4 0.0 4.0 35.6 0.0 6.4 0.0 1.0 0.0 0.1 105.2 140.5 0.7 79.7 53.1 10.2 15.7 204.1 0.0 0.0 0.0 14.9 0.2 11.0 16.1 11.8 1.0 12.9 0.3 53.9 175.3 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 39.1;lymphoid tissue: 46.7" "Cell type enriched" "Detected in some" 11 "B-cells: 116.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 183.4;naive B-cell: 131.5" "Lineage enriched" "Detected in many" 5 "B-cells: 183.4" "Cell line enhanced" "Detected in some" "Daudi: 106.6;REH: 29.9;RPMI-8226: 38.5;U-698: 48.6;U-87 MG: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.1 0.0 9.1 0.0 2.6 0.2 0.0 0.0 0.0 0.0 2.6 0.5 0.1 0.0 1.2 0.2 0.5 0.1 0.0 0.0 1.2 0.7 0.8 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.0 0.7 0.0 0.3 0.0 39.1 0.1 0.0 46.7 2.1 0.1 0.0 2.5 1.2 0.0 27.9 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 29.9 0.0 38.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 5.4 10.2 48.6 22.7 0.0 0.0 0.2 0.1 0.2 2.0 0.0 37.9 183.4 1.4 4.6 0.1 131.5 0.9 0.4 0.7 0.1 0.1 17.5 1.8 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 116.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.1 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.0 BLOC1S1 "BLOS1, BORCS1, GCN5L1" ENSG00000135441 "Biogenesis of lysosomal organelles complex 1 subunit 1" P78537 12 55716037-55720087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 1180.5;Proximal tubular cells: 719.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA021381 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA021381: AB_2228026" "unprognostic (1.27e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (1.59e-1)" "unprognostic (6.77e-2)" "unprognostic (2.22e-1)" "prognostic favorable (2.19e-4)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (1.83e-2)" 125.6 168.5 248.4 81.5 256.8 223.7 112.5 261.4 294.0 94.0 248.6 184.6 145.3 118.9 151.1 177.1 133.4 77.0 169.7 249.4 260.6 196.1 219.3 113.0 107.5 259.1 254.9 93.6 110.1 175.6 109.6 71.6 258.7 113.1 167.5 81.7 107.3 77.1 309.8 114.8 155.4 99.7 258.9 174.9 164.8 55.0 250.9 146.8 118.8 201.1 111.7 125.2 106.2 271.6 134.9 258.3 133.7 113.3 170.6 217.1 75.7 93.7 154.4 112.9 111.8 148.5 267.3 148.6 166.5 194.6 95.2 91.7 70.8 132.4 110.9 142.5 160.5 84.6 220.5 224.9 163.6 104.5 177.7 139.8 137.3 108.2 83.1 145.8 152.4 172.0 77.5 221.0 183.3 294.0 164.3 123.8 84.6 219.1 134.2 110.9 129.9 163.3 182.9 164.2 85.1 141.6 85.1 86.0 150.5 93.2 177.5 169.2 114.2 87.2 142.7 96.5 74.0 99.4 126.2 134.6 158.8 97.2 121.8 612.0 471.8 746.5 238.6 543.1 162.2 345.1 224.4 239.8 486.6 326.5 160.9 201.1 631.4 221.7 586.1 409.0 318.2 637.9 248.4 256.8 261.4 294.0 249.4 260.6 259.1 254.9 258.7 258.9 250.9 271.6 155.2 16.0 20.7 0.0 110.4 83.1 120.0 143.2 61.5 51.6 123.8 158.5 37.6 160.2 92.0 160.0 25.0 98.1 159.5 439.5 369.8 207.3 53.7 123.9 60.6 92.1 99.5 191.3 0.0 320.7 182.3 105.1 103.0 88.6 20.2 77.9 122.4 378.7 430.7 30.3 0.0 266.8 179.0 403.1 213.2 213.9 134.2 238.6 176.1 0.0 347.9 192.0 230.7 0.0 0.0 291.0 409.3 98.9 66.9 122.6 1180.5 719.6 114.2 92.9 78.9 133.9 208.5 46.9 55.0 86.6 88.9 73.2 111.5 77.4 256.7 180.7 BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 47.3;Fibroblasts: 65.2;Hepatic stellate cells: 52.8;Pancreatic endocrine cells: 40.1;Skeletal myocytes: 51.0;Syncytiotrophoblasts: 34.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cell line enhanced" "Detected in many" "CACO-2: 120.1;CAPAN-2: 298.6;Hep G2: 326.0;OE19: 219.1;SuSa: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" NA NA 162000000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" 14.0 13.4 3.0 6.1 3.2 0.1 13.4 7.0 4.5 21.0 32.4 25.6 17.0 8.9 2.5 12.9 9.7 14.4 16.3 3.1 2.8 9.0 4.2 13.4 9.6 3.6 3.3 23.8 3.4 2.7 4.7 44.4 3.9 21.9 28.9 2.7 10.5 18.7 11.5 15.3 19.2 9.0 3.2 6.5 23.8 2.0 3.9 3.4 8.5 17.7 4.2 27.4 23.5 4.7 15.6 40.0 2.1 1.8 0.5 0.4 0.6 7.9 34.0 20.1 15.5 120.1 298.6 0.0 97.2 0.1 2.2 73.2 8.6 1.0 10.7 4.1 5.9 0.2 8.3 326.0 19.4 0.0 1.0 0.0 2.8 9.5 0.5 61.1 59.3 6.8 0.0 0.3 9.7 6.9 5.3 0.3 13.9 219.1 3.4 0.2 10.5 0.3 28.5 1.3 0.1 0.3 0.0 1.1 0.9 168.2 38.8 1.5 2.9 0.6 87.1 0.3 1.4 0.2 0.1 1.0 0.1 0.1 4.3 0.0 0.6 0.0 0.1 1.1 0.0 0.0 0.9 0.2 0.1 0.0 1.3 0.4 0.0 0.0 1.9 0.0 0.0 0.3 3.0 3.2 7.0 4.5 3.1 2.8 3.6 3.3 3.9 3.2 3.9 4.7 7.6 9.6 7.3 1.0 0.6 27.5 4.0 16.1 47.3 0.3 8.0 10.4 5.7 14.3 6.0 5.5 0.0 29.3 0.1 1.0 3.9 5.5 2.5 0.7 18.9 18.2 0.0 2.7 1.3 0.2 18.9 65.2 0.5 0.7 1.3 0.9 52.8 2.0 3.7 0.0 0.4 5.3 2.0 0.6 5.9 1.0 10.5 0.4 3.6 1.9 0.0 0.5 0.0 1.0 0.3 40.1 4.0 1.5 0.1 2.3 0.6 2.4 5.8 1.5 0.0 51.0 10.5 1.4 2.2 7.5 17.5 34.8 1.0 1.4 4.0 1.4 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 BRAT1 "BAAT1, C7orf27, MGC22916" ENSG00000106009 "BRCA1 associated ATM activator 1" Q6PJG6 7 2537810-2555694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029455, HPA076508" Approved Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA029455: AB_10600761, HPA076508: AB_2686803" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.04e-3)" "unprognostic (6.07e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (8.02e-4)" "unprognostic (2.03e-1)" "unprognostic (1.76e-1)" "unprognostic (2.46e-1)" "unprognostic (1.10e-3)" "unprognostic (4.69e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (5.37e-2)" "unprognostic (3.12e-2)" "unprognostic (8.88e-2)" "unprognostic (3.71e-2)" 17.4 31.0 10.7 6.8 10.9 7.9 17.8 10.4 14.3 22.5 9.6 16.2 8.8 19.4 2.2 15.1 19.2 3.7 14.5 10.4 11.2 15.2 20.7 12.2 7.2 13.5 11.4 21.6 20.2 5.2 19.8 4.5 10.1 24.5 1.3 0.9 17.4 6.6 14.8 21.6 16.6 2.5 10.6 21.1 19.6 31.5 11.2 5.0 18.7 3.7 2.1 17.6 18.8 10.5 35.1 31.1 7.5 27.2 6.8 6.3 24.5 11.7 6.5 10.1 8.5 22.5 21.5 26.3 18.1 7.8 19.4 35.1 8.8 13.7 1.6 10.4 44.4 12.2 23.5 14.3 8.7 16.5 18.2 10.6 9.5 10.2 3.0 5.8 11.4 20.2 39.1 9.6 7.1 50.0 11.8 77.9 35.3 8.8 47.0 28.6 21.9 25.5 6.5 11.3 19.5 30.2 17.1 29.8 12.9 3.5 26.5 33.4 11.8 13.8 43.3 28.5 23.2 20.7 17.3 19.0 15.2 32.8 33.2 5.1 30.8 17.5 21.9 28.2 19.3 18.6 19.8 22.6 32.4 15.2 16.3 17.9 25.4 15.9 27.1 22.7 18.4 22.8 10.7 10.9 10.4 14.3 10.4 11.2 13.5 11.4 10.1 10.6 11.2 10.5 10.1 12.8 6.4 19.9 11.1 7.8 17.5 22.6 16.5 12.8 11.3 8.9 6.8 15.7 14.8 9.2 12.5 21.1 15.0 14.8 15.6 10.6 20.8 7.1 12.3 13.0 11.4 10.3 14.2 13.8 12.9 12.8 26.0 7.5 14.0 34.9 15.4 15.3 34.2 3.3 16.2 14.8 8.2 13.1 6.7 9.4 22.7 13.3 7.2 12.2 17.6 14.4 9.2 13.6 11.3 12.0 12.1 22.2 14.4 9.1 15.0 16.6 8.1 11.9 6.6 9.4 10.7 28.8 39.5 8.0 6.8 14.6 11.9 31.7 17.9 7.6 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BTLA "BTLA1, CD272" ENSG00000186265 "B and T lymphocyte associated" Q7Z6A9 3 112463966-112499472 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 28.6" "Cell type enriched" "Detected in some" 4 "B-cells: 66.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 65.0;naive B-cell: 96.5;plasmacytoid DC: 24.9" "Group enriched" "Detected in many" 4 "B-cells: 96.5;dendritic cells: 24.9" "Cell line enhanced" "Detected in single" "U-698: 2.0" "Not detected" "Not detected" "HPA047211, HPA062029" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA047211: AB_2679983, HPA062029: AB_2684665" "unprognostic (1.13e-3)" "unprognostic (2.13e-3)" "unprognostic (5.79e-4)" "unprognostic (1.01e-4)" "unprognostic (7.08e-2)" "unprognostic (7.74e-6)" "unprognostic (6.20e-3)" "unprognostic (7.59e-3)" "unprognostic (5.98e-2)" "unprognostic (1.53e-5)" "unprognostic (2.33e-2)" "unprognostic (1.23e-1)" "unprognostic (1.57e-5)" "unprognostic (2.57e-1)" "unprognostic (2.46e-2)" "unprognostic (1.65e-1)" "unprognostic (1.42e-2)" 0.4 0.3 0.0 11.2 0.0 2.1 1.9 0.1 0.4 0.5 0.0 1.7 1.6 0.3 0.1 0.6 0.3 1.1 0.2 0.0 0.0 0.3 0.6 0.9 26.4 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.1 0.4 1.6 0.2 1.3 0.1 0.1 0.1 3.1 0.4 0.0 10.8 3.0 0.1 0.0 7.7 0.3 0.1 28.6 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.1 0.0 11.2 0.0 8.3 65.0 13.6 6.5 4.6 96.5 12.7 12.6 0.5 0.3 0.1 24.9 3.4 6.5 0.0 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.5 0.0 66.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.3 0.8 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.5 1.3 0.0 0.4 0.2 0.1 0.0 0.4 0.0 0.0 1.3 4.7 3.6 0.0 1.6 7.2 0.0 1.9 0.0 0.0 1.0 0.3 0.0 0.0 0.0 15.9 0.0 0.0 0.2 0.7 0.0 0.0 0.3 0.1 0.2 0.3 0.0 0.3 0.1 8.6 0.0 0.0 0.1 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BTN3A2 BTN3.2 ENSG00000186470 "Butyrophilin subfamily 3 member A2" P78410 6 26365159-26378320 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 88.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.2;NK-cells: 239.9;T-cells: 108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 87.5" CAB019392 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB019392: " "unprognostic (3.77e-2)" "unprognostic (1.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.86e-2)" "unprognostic (3.66e-2)" "unprognostic (1.60e-1)" "unprognostic (1.40e-1)" "unprognostic (3.89e-1)" "unprognostic (4.04e-2)" "unprognostic (1.30e-3)" "unprognostic (1.12e-1)" "unprognostic (8.45e-2)" "prognostic unfavorable (4.24e-4)" "unprognostic (5.13e-2)" "unprognostic (4.45e-2)" "unprognostic (4.42e-2)" "unprognostic (1.48e-3)" 19.4 27.3 8.6 41.9 8.5 9.5 18.4 7.6 8.7 18.1 7.9 29.0 29.3 21.7 21.0 13.5 22.0 25.0 13.8 7.3 9.3 15.8 23.6 41.0 45.5 13.1 8.9 29.6 10.4 10.4 12.7 18.4 9.9 14.9 31.7 2.4 19.4 14.9 8.4 21.7 32.9 20.8 10.5 88.3 32.6 7.1 8.7 38.3 14.4 10.7 44.6 22.9 17.0 10.9 10.6 4.8 6.4 6.7 37.4 42.9 2.2 10.2 48.2 18.8 52.6 2.7 34.4 30.6 35.5 16.2 27.5 9.2 9.4 18.6 17.1 18.5 13.2 33.1 19.1 20.1 20.7 18.9 26.5 27.0 7.5 17.9 8.5 43.9 36.0 54.0 8.5 41.1 13.1 1.4 16.2 30.4 0.4 8.6 3.6 24.3 11.5 87.5 17.1 6.5 4.2 12.8 8.2 7.5 25.7 1.9 7.5 14.0 22.4 17.7 4.0 7.6 11.3 86.1 79.7 17.7 32.2 33.2 17.5 67.7 26.7 57.6 128.3 35.9 96.1 64.5 81.3 113.8 19.2 53.4 81.8 100.1 40.0 98.8 47.5 13.5 111.2 71.3 8.6 8.5 7.6 8.7 7.3 9.3 13.1 8.9 9.9 10.5 8.7 10.9 62.5 32.1 22.2 2.3 61.3 10.3 12.2 8.6 13.1 0.7 16.0 9.9 7.5 17.2 7.4 12.9 0.0 14.3 117.2 21.8 1.9 25.6 0.2 23.6 21.3 46.0 10.1 25.2 1.0 13.7 17.3 20.2 15.8 14.7 47.4 23.4 40.0 9.8 17.8 0.0 2.5 37.9 10.2 54.0 10.0 1.9 11.1 37.1 3.6 20.6 52.7 7.0 239.9 7.1 1.7 10.6 16.9 10.5 76.6 13.2 50.5 3.8 11.8 1.4 13.1 15.7 10.2 1.5 0.2 8.3 13.4 3.3 108.0 51.0 25.5 16.8 BTN3A3 "BTF3, BTN3.3" ENSG00000111801 "Butyrophilin subfamily 3 member A3" O00478 6 26440472-26453415 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 26.9;NK-cells: 33.0;Plasma cells: 30.5;T-cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;BJ hTERT+ SV40 Large T+ RasG12V: 43.8" "HPA007904, HPA011871" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "HPA007904: AB_1078307, HPA011871: AB_1845496" "unprognostic (1.18e-2)" "unprognostic (6.54e-3)" "unprognostic (1.54e-1)" "unprognostic (1.19e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (5.13e-3)" "unprognostic (8.08e-2)" "unprognostic (7.88e-2)" "prognostic favorable (1.80e-4)" "unprognostic (4.45e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (3.49e-2)" "unprognostic (2.14e-2)" "unprognostic (5.26e-2)" "unprognostic (4.54e-3)" 14.9 19.6 7.4 20.0 7.0 5.5 12.0 6.5 7.9 16.6 8.0 15.0 17.5 16.7 18.7 8.3 20.3 20.3 9.0 7.2 9.0 8.9 20.6 33.7 29.2 10.0 7.2 19.5 4.8 5.0 12.2 10.2 7.6 9.4 14.6 1.8 12.3 11.2 5.8 11.6 16.7 17.1 9.0 47.2 16.3 3.3 7.5 21.5 9.2 14.4 22.8 16.7 9.5 8.2 4.1 1.8 1.8 1.6 33.2 62.8 0.5 5.4 29.7 12.0 43.8 0.0 12.3 25.0 24.5 9.0 11.1 2.9 2.6 9.7 5.8 21.4 4.2 11.5 11.8 1.3 24.2 6.4 2.1 33.4 3.8 10.5 3.9 19.3 24.1 9.4 0.5 3.7 6.7 0.0 16.7 5.3 0.1 0.0 2.9 16.7 3.3 24.9 9.4 3.3 2.2 3.9 3.3 3.1 6.2 0.4 0.8 3.5 15.0 5.8 1.3 6.5 3.8 4.1 1.0 2.5 15.4 12.0 6.2 49.0 15.7 13.4 54.7 23.2 43.7 19.3 37.6 55.5 12.4 14.0 36.3 49.0 11.6 45.9 24.6 6.4 46.2 33.3 7.4 7.0 6.5 7.9 7.2 9.0 10.0 7.2 7.6 9.0 7.5 8.2 20.3 9.6 7.7 0.3 15.9 1.8 1.9 2.8 8.0 0.2 3.6 2.8 4.9 0.0 5.2 0.0 0.0 2.5 26.9 6.4 1.9 5.3 4.6 4.2 9.4 22.1 1.2 9.9 1.4 2.3 1.6 11.1 7.1 4.3 3.8 8.7 15.7 4.0 4.3 0.0 2.1 8.9 0.0 20.8 4.0 18.0 4.1 12.4 3.6 2.8 12.6 2.3 33.0 1.5 0.4 2.4 3.9 2.2 30.5 2.0 12.8 1.1 3.3 0.0 6.6 4.9 4.0 0.4 0.3 3.1 2.0 0.5 27.1 12.3 6.2 1.9 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C12orf43 "Custos, FLJ12448" ENSG00000157895 "Chromosome 12 open reading frame 43" Q96C57 12 121000486-121016502 "Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046148, HPA061739" Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 30: Non-specific - Translation" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Golgi apparatus" "HPA046148: AB_10965169, HPA061739: AB_2684597" "unprognostic (1.51e-1)" "unprognostic (5.75e-2)" "unprognostic (3.44e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (6.44e-4)" "unprognostic (3.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.95e-1)" "unprognostic (2.45e-3)" "unprognostic (9.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" 9.8 8.1 11.7 6.9 11.9 7.4 9.3 8.8 13.6 7.8 7.2 11.2 5.0 9.5 4.4 7.2 9.0 5.1 7.4 12.3 9.5 8.2 10.5 6.7 8.7 10.9 9.6 11.2 7.5 9.0 7.4 7.2 10.8 7.7 5.3 6.0 8.7 6.2 7.2 6.7 6.7 8.4 8.6 7.8 8.2 6.1 9.4 7.2 6.4 5.9 7.4 9.6 7.0 10.4 14.2 31.4 16.2 12.8 14.0 11.0 17.8 17.2 17.5 28.3 17.9 22.8 13.0 26.2 17.2 16.8 15.0 15.7 19.2 26.3 16.8 31.6 21.4 21.1 12.4 17.1 16.7 28.1 16.2 12.9 13.6 26.0 16.4 17.9 16.4 27.0 25.5 6.7 15.1 23.3 30.9 22.0 28.8 11.1 23.2 27.4 19.0 19.8 17.5 20.8 22.0 14.0 23.0 9.9 18.6 13.4 27.0 13.1 15.9 15.6 18.7 12.8 18.4 12.3 19.1 20.5 20.5 16.5 23.6 5.7 15.6 9.0 23.8 21.3 21.8 23.8 23.5 23.2 16.1 19.0 27.5 23.6 2.2 18.4 18.5 13.3 23.8 20.6 11.7 11.9 8.8 13.6 12.3 9.5 10.9 9.6 10.8 8.6 9.4 10.4 16.1 25.6 18.1 3.3 17.3 8.8 16.4 12.2 6.8 19.6 12.4 12.4 7.0 11.5 9.6 18.4 20.9 24.3 13.9 8.6 23.5 16.5 5.9 9.8 17.1 16.0 2.4 10.7 6.8 18.5 22.3 16.3 8.2 10.1 14.5 22.3 12.5 11.7 16.7 16.8 6.4 9.5 10.2 10.4 7.3 13.8 13.7 13.2 14.2 3.7 21.7 18.8 24.7 4.0 4.8 15.6 12.3 12.8 11.3 13.8 5.3 16.7 16.3 15.7 19.7 19.6 16.9 16.3 16.4 12.7 7.7 13.7 17.6 16.0 10.9 14.0 C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 39 "testis: 40.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2541.6" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HBEC3-KT: 2.7" "Not detected" "Not detected" HPA073090 Approved "Intermediate filaments" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments" "HPA073090: " "unprognostic (2.59e-3)" "unprognostic (5.49e-2)" "unprognostic (7.94e-3)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (8.99e-2)" "unprognostic (5.96e-2)" "unprognostic (1.62e-1)" "unprognostic (8.01e-2)" "unprognostic (1.36e-4)" "unprognostic (2.37e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" 0.0 0.4 0.3 0.0 0.4 0.0 0.2 0.2 1.0 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.3 0.3 0.1 0.0 40.4 0.3 0.0 0.0 0.2 0.6 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.0 0.3 0.2 0.5 0.4 0.5 0.3 0.3 0.5 0.0 0.0 2.6 8.1 0.0 5.1 38.6 19.5 1.2 0.2 0.2 0.1 0.7 0.0 4.5 0.0 0.0 0.1 0.0 0.0 1.9 0.1 543.1 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.2 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 9.1 0.0 2.0 0.0 1.8 2541.6 10.8 1.4 0.0 2.8 0.0 0.3 0.0 4.5 2.5 0.0 0.0 13.2 0.0 6.4 0.0 1.9 1.9 0.2 6.6 4.3 1.0 11.5 6.5 5.9 2.3 0.0 0.5 0.4 0.0 10.8 C14orf132 C14orf88 ENSG00000227051 "Chromosome 14 open reading frame 132" Q9NPU4 14 96039362-96093971 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 74.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Bipolar cells: 57.8;Endometrial ciliated cells: 55.2;Horizontal cells: 63.9;Skeletal myocytes: 44.9" "Cancer enhanced" "Detected in many" "glioma: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 49.9;SCLC-21H: 52.5;SH-SY5Y: 52.0;U-87 MG: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.47e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-1)" "unprognostic (1.82e-1)" "unprognostic (4.42e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.51e-2)" "unprognostic (5.55e-3)" "unprognostic (1.47e-2)" "unprognostic (3.09e-2)" "unprognostic (1.33e-5)" "prognostic unfavorable (4.95e-4)" 5.9 14.0 57.3 3.2 58.1 0.1 6.9 62.8 69.1 23.3 20.5 23.8 2.1 26.2 14.2 7.1 22.5 5.0 4.1 74.7 52.5 9.9 4.1 18.4 0.8 53.6 49.8 5.2 3.2 0.1 38.8 0.8 50.9 9.5 4.4 12.8 3.0 19.8 3.0 13.8 14.2 22.3 51.2 6.2 15.7 1.3 55.8 3.1 2.4 6.6 1.2 8.5 11.9 56.1 0.0 6.4 30.8 9.7 22.0 22.0 0.1 10.6 23.8 13.6 8.3 0.1 0.1 0.0 2.4 23.8 9.0 0.7 3.7 0.8 11.7 0.0 1.4 0.1 1.2 0.1 2.7 0.0 0.2 12.0 1.2 12.7 1.0 0.0 0.2 3.0 0.0 0.1 6.3 49.9 0.8 0.1 15.0 0.0 0.0 28.5 5.0 0.1 11.0 22.4 52.5 52.0 8.3 1.0 1.5 8.3 28.9 1.4 0.0 10.8 6.5 18.0 0.0 0.0 0.0 0.1 46.1 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.2 57.3 58.1 62.8 69.1 74.7 52.5 53.6 49.8 50.9 51.2 55.8 56.1 4.8 38.5 10.6 14.7 0.4 2.7 3.7 5.9 5.2 57.8 0.7 7.1 1.9 1.5 3.9 7.3 20.9 0.3 0.2 0.0 5.9 5.8 3.0 55.2 23.8 8.6 9.0 0.0 20.3 0.2 1.0 16.6 2.0 6.8 1.3 5.4 19.2 4.0 0.3 63.9 11.2 0.1 4.1 0.6 7.1 3.0 15.8 0.5 8.8 7.5 0.1 4.0 0.0 11.1 24.7 1.2 0.1 13.5 0.1 2.1 0.0 0.0 13.6 6.1 0.0 44.9 4.4 0.3 0.6 6.8 7.7 0.3 1.0 0.6 0.1 2.3 C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.9;Paneth cells: 100.8;Proximal enterocytes: 128.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "A-431: 12.1;BEWO: 13.0;CACO-2: 12.6;CAPAN-2: 39.8;OE19: 33.1;SK-BR-3: 13.8;T-47d: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" 0.2 0.1 0.3 2.9 0.3 0.2 14.5 0.7 0.5 8.2 0.3 32.4 43.9 1.3 13.0 17.0 6.1 9.9 0.1 0.3 0.2 21.8 6.2 9.0 0.1 0.3 0.4 0.1 22.8 10.3 8.4 1.6 0.4 8.1 30.2 0.5 19.5 3.8 0.0 16.2 38.7 1.2 0.2 0.1 29.1 0.3 0.3 1.0 16.9 0.0 2.3 3.2 8.1 0.8 12.1 0.0 0.0 0.1 0.0 0.0 13.0 0.0 0.0 0.0 0.0 12.6 39.8 0.0 0.3 0.0 0.0 9.0 0.0 5.6 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.0 0.0 0.2 0.1 33.1 0.0 0.1 0.1 0.4 1.0 7.8 4.6 0.3 0.1 13.8 0.0 2.1 15.2 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.7 0.5 0.3 0.2 0.3 0.4 0.4 0.2 0.3 0.8 0.1 22.4 16.1 0.3 0.6 1.1 6.2 11.5 2.8 0.0 22.4 12.8 0.0 28.6 13.8 22.0 0.0 12.9 0.0 125.9 29.4 21.3 0.1 8.5 1.4 0.2 33.6 0.0 0.0 33.7 3.9 0.2 25.5 14.2 0.0 0.0 0.0 1.2 0.7 0.0 0.0 42.4 8.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.3 100.8 0.0 0.0 6.6 128.1 39.6 7.3 0.0 0.0 0.0 0.7 0.3 0.0 8.9 2.6 4.7 0.3 0.0 37.0 8.8 C1R ENSG00000159403 "Complement C1r" 12 7080214-7092540 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "liver: 1425.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 442.3;Fibroblasts: 684.4;Hepatocytes: 1444.2;Leydig cells: 1142.6;Peritubular cells: 388.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1089.8;ASC TERT1: 546.0;BJ hTERT+: 461.9;BJ hTERT+ SV40 Large T+ RasG12V: 303.4;HSkMC: 672.1" "Low region specificity" "Detected in many" "HPA001251, HPA001551" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001251: AB_2666252, HPA001551: AB_10754818" "unprognostic (1.55e-2)" "unprognostic (8.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.92e-1)" "unprognostic (1.47e-2)" "unprognostic (2.66e-2)" "unprognostic (1.94e-2)" "unprognostic (2.05e-1)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (1.21e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (1.94e-14)" "unprognostic (3.54e-2)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" 540.6 203.6 15.8 122.4 15.9 1.1 400.6 15.9 23.3 470.5 21.7 277.3 38.3 353.8 80.8 119.0 526.3 279.1 458.7 15.4 19.6 148.9 1425.6 340.3 72.4 23.4 19.9 644.3 88.0 11.0 63.9 52.4 18.4 205.2 100.9 5.8 158.3 87.0 69.4 177.7 228.1 157.7 18.1 192.1 242.7 46.7 18.1 34.7 223.4 74.2 75.3 468.4 394.3 18.0 1.2 8.9 0.9 9.1 1089.8 546.0 0.4 108.9 461.9 143.0 303.4 1.4 2.4 0.5 4.5 108.8 11.8 2.3 11.8 5.5 18.3 18.3 1.1 0.5 4.1 3.6 226.5 0.8 2.3 672.1 3.2 74.7 4.7 121.0 2.9 0.5 0.3 20.5 21.2 0.1 8.0 0.8 3.1 0.1 0.9 8.6 3.8 0.8 0.9 5.5 0.4 2.3 95.1 3.7 2.8 1.3 0.2 0.2 0.4 38.3 6.3 152.1 0.8 1.1 3.0 0.2 53.1 1.0 5.4 0.0 0.0 0.6 0.3 0.0 0.5 0.0 0.2 0.7 0.0 0.0 0.6 0.6 0.5 0.8 0.0 0.0 0.3 0.1 15.8 15.9 15.9 23.3 15.4 19.6 23.4 19.9 18.4 18.1 18.1 18.0 45.4 22.4 90.5 3.6 7.1 54.7 58.8 76.6 33.6 0.3 5.9 30.9 20.8 183.0 22.9 18.4 2.1 4.1 1.8 0.7 3.9 280.8 4.6 13.3 442.3 45.4 0.0 40.6 0.9 44.5 3.7 684.4 16.3 11.6 10.1 24.9 114.9 1444.2 11.2 0.0 0.3 0.7 0.0 40.9 66.9 29.2 1142.6 7.0 53.4 13.1 1.6 16.0 0.0 2.5 0.1 51.1 1.3 388.1 6.2 17.7 0.3 6.1 5.3 1.4 170.9 87.5 140.4 6.8 6.7 5.6 40.1 5.2 11.5 15.2 0.7 11.2 C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 115.8;liver: 336.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 46.4;Cardiomyocytes: 8.3;Club cells: 13.6;Fibroblasts: 19.1" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 58.5;HSkMC: 72.8;U-266/70: 17.1;U-266/84: 33.9" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" NA NA 342000000 120000000000 "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" 27.9 115.8 0.2 10.6 1.6 0.4 15.7 0.3 2.2 12.6 0.2 31.3 7.5 16.9 11.8 2.6 29.9 2.3 21.8 0.5 1.2 43.1 336.8 14.9 4.5 5.8 1.9 57.5 23.0 0.6 20.6 0.5 2.3 11.1 3.7 5.5 14.2 0.0 1.7 1.7 17.0 0.0 0.5 15.3 11.7 4.1 1.7 4.2 44.5 0.0 2.9 23.1 4.1 1.4 0.0 0.3 0.0 0.0 1.0 5.2 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.7 0.2 0.1 0.1 0.4 0.0 58.5 0.5 0.0 0.3 1.0 0.0 0.0 0.0 72.8 0.0 0.0 0.0 0.5 0.0 0.6 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.2 17.1 33.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.3 2.2 0.5 1.2 5.8 1.9 2.3 0.5 1.7 1.4 0.0 9.6 46.4 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 8.3 2.8 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.4 6.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.5 4.4 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 C5orf49 LOC134121 ENSG00000215217 "Chromosome 5 open reading frame 49" A4QMS7 5 7830378-7851151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 29.1;choroid plexus: 27.4;fallopian tube: 75.7;testis: 37.1" "Group enriched" "Detected in many" 11 "Early spermatids: 821.2;Endometrial ciliated cells: 353.9;Late spermatids: 410.2;Respiratory ciliated cells: 502.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043759 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA043759: AB_2678655" "unprognostic (1.55e-1)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (2.13e-3)" "unprognostic (4.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (7.93e-2)" "unprognostic (7.54e-3)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-2)" "unprognostic (2.20e-2)" 0.2 0.5 15.2 0.1 17.0 0.0 0.8 12.3 16.5 4.2 27.4 0.1 0.1 1.4 1.7 0.0 75.7 0.5 0.2 15.9 18.1 3.9 3.3 6.0 0.0 21.9 29.1 1.0 2.7 6.2 10.4 0.1 22.0 3.5 0.0 1.4 0.3 1.3 0.0 0.6 0.1 0.3 19.1 0.1 0.6 37.1 19.7 0.7 0.8 0.0 0.0 0.2 0.8 18.1 0.0 0.2 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.2 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 17.0 12.3 16.5 15.9 18.1 21.9 29.1 22.0 19.1 19.7 18.1 0.1 0.0 5.4 2.3 1.0 0.0 2.6 32.0 0.0 0.4 4.7 3.0 0.4 1.5 41.4 9.2 0.0 0.2 0.0 0.0 3.9 5.6 821.2 353.9 4.3 1.2 5.4 0.0 2.8 0.9 2.9 1.7 0.0 5.8 1.3 0.2 0.4 0.8 0.1 1.7 3.5 0.2 46.8 0.0 0.4 410.2 8.7 0.8 3.6 1.0 0.0 2.3 0.0 1.5 0.2 1.6 0.0 3.8 0.0 4.1 0.0 39.9 502.4 3.6 6.6 0.8 13.4 41.1 8.4 0.0 0.6 0.3 0.9 0.1 0.0 1.5 C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 340.1;Late spermatids: 699.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 351.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "HPA012548: AB_1845748" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.77e-5)" "unprognostic (3.75e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-3)" "unprognostic (8.42e-3)" 37.4 37.5 24.6 27.3 28.8 37.6 32.0 26.1 24.6 45.8 22.7 33.8 28.1 36.8 50.0 35.4 38.5 33.1 49.7 26.7 31.2 32.9 34.1 32.8 24.7 29.0 29.4 44.9 46.2 54.3 28.2 33.3 29.1 37.0 37.1 13.4 42.3 47.6 36.6 24.2 27.5 45.0 29.9 24.9 33.4 47.5 30.2 30.2 58.2 44.3 31.4 31.7 26.5 35.3 37.9 22.9 31.1 44.8 111.0 76.2 18.3 73.1 91.6 50.5 55.2 23.7 39.2 33.6 55.5 150.6 54.1 40.3 38.3 46.0 72.9 60.4 33.2 48.8 23.3 26.8 55.5 39.6 48.3 66.0 56.2 62.0 58.9 60.4 44.5 60.1 93.8 90.1 79.0 37.7 43.5 15.0 11.6 43.1 25.7 21.1 30.9 61.1 33.7 33.2 54.9 39.5 48.8 23.5 50.8 25.8 56.0 53.3 52.7 72.3 41.2 57.6 57.4 48.4 63.8 351.0 32.6 55.8 77.3 28.1 16.7 20.9 18.1 16.4 17.9 9.8 14.8 16.8 14.7 9.1 10.2 11.2 27.2 11.2 22.5 9.2 16.4 14.4 24.6 28.8 26.1 24.6 26.7 31.2 29.0 29.4 29.1 29.9 30.2 35.3 31.2 38.5 56.8 22.9 24.6 6.8 23.9 28.8 19.4 15.5 24.6 19.0 67.1 41.5 31.6 38.6 10.4 34.0 26.6 39.2 19.6 41.2 340.1 24.9 36.1 36.1 17.4 56.0 38.4 58.1 41.6 37.7 27.5 33.7 30.4 52.6 25.0 45.5 40.0 23.5 35.3 27.9 32.6 29.8 12.5 699.2 45.1 27.2 10.6 29.0 24.9 53.9 28.8 31.7 54.5 56.3 27.9 50.8 44.1 26.6 30.5 20.1 28.3 12.8 19.7 35.8 36.9 33.7 38.5 23.5 8.9 46.0 28.5 50.8 25.9 26.1 C9orf116 "MGC29761, PIERCE1, RbEST47" ENSG00000160345 "Chromosome 9 open reading frame 116" Q5BN46 9 135495181-135501734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 97.2;testis: 62.5" "Group enriched" "Detected in many" 4 "Early spermatids: 520.9;Endometrial ciliated cells: 442.5;Late spermatids: 579.4;Respiratory ciliated cells: 610.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 41.3;T-47d: 41.9;U-2197: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021439, HPA065287" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA021439: AB_1845799, HPA065287: AB_2732732" "unprognostic (9.02e-2)" "unprognostic (1.36e-2)" "unprognostic (1.93e-1)" "prognostic favorable (3.53e-5)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (4.23e-1)" "unprognostic (2.58e-1)" "unprognostic (5.30e-2)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (4.23e-3)" "unprognostic (3.86e-2)" "unprognostic (8.75e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" 2.6 16.3 11.9 0.8 12.8 0.9 3.1 10.7 13.0 5.5 24.5 2.1 1.0 4.2 25.7 1.9 97.2 2.8 2.0 14.0 13.6 9.5 3.5 9.2 0.7 15.8 19.7 2.8 6.5 6.8 16.9 1.5 15.9 4.2 1.2 10.1 3.4 6.3 1.5 1.8 1.4 1.2 15.4 1.9 3.1 62.5 14.5 0.6 8.1 0.9 1.2 2.7 1.5 13.0 11.0 18.7 8.1 12.7 3.5 7.4 1.6 7.3 5.1 8.7 5.9 7.1 10.9 1.9 9.5 4.9 4.7 7.4 9.1 4.1 7.4 0.5 8.0 0.0 21.0 22.1 9.7 1.5 5.0 5.2 3.2 4.4 1.4 7.1 4.2 8.6 10.3 1.4 4.2 41.3 5.7 1.9 17.1 17.2 21.5 8.7 3.9 6.9 21.0 7.7 7.9 8.3 10.3 4.4 1.2 3.7 41.9 1.8 2.1 5.0 6.5 42.9 2.9 4.7 12.6 1.8 14.7 0.7 1.5 0.0 0.8 0.0 0.5 0.5 1.2 0.2 0.4 0.4 0.3 0.4 0.7 0.5 0.0 0.6 0.1 0.1 0.5 0.3 11.9 12.8 10.7 13.0 14.0 13.6 15.8 19.7 15.9 15.4 14.5 13.0 1.2 9.6 7.8 2.3 1.9 0.9 1.8 39.7 2.2 5.0 11.7 9.8 1.7 15.7 46.3 14.7 14.6 11.5 0.7 0.5 11.7 26.0 520.9 442.5 6.6 2.1 1.2 1.3 2.1 7.8 3.4 5.2 4.6 23.9 1.3 12.0 0.7 1.6 3.6 3.3 2.2 1.0 38.7 1.2 1.4 579.4 8.1 1.3 0.0 0.0 2.0 13.2 0.0 1.0 0.2 6.9 1.7 7.5 3.6 2.4 1.3 58.8 610.3 19.9 0.0 1.4 15.0 133.8 20.0 1.3 0.3 4.5 1.6 41.4 1.7 3.1 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 295 "salivary gland: 9393.1" "Group enriched" "Detected in some" 44 "Breast glandular cells: 77.9;Ionocytes: 99.7;Melanocytes: 179.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.6;naive CD8 T-cell: 16.4" "Lineage enriched" "Detected in many" 11 "T-cells: 16.4" "Cell line enhanced" "Detected in some" "Daudi: 1.7;U-2197: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" NA NA 24000000 "Cluster 32: T-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" 0.4 0.4 0.3 0.7 0.6 2.0 20.8 0.9 0.7 0.0 0.5 0.1 0.3 0.2 2.3 0.2 0.1 0.2 1.5 0.4 0.3 0.1 0.1 0.3 1.3 0.9 0.4 1.9 6.3 0.0 0.1 0.9 0.7 0.2 0.2 0.7 9393.1 0.0 0.4 31.8 0.5 0.0 0.1 1.2 0.4 0.3 0.7 1.2 0.3 0.0 1.0 0.1 0.0 1.8 0.2 0.0 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.3 0.4 1.7 0.1 0.1 0.4 0.3 0.1 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.0 0.5 0.5 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.4 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.3 0.2 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.6 0.3 1.3 0.2 0.4 0.1 0.4 0.1 0.4 0.4 1.4 0.3 0.2 0.3 0.2 0.3 0.3 0.7 2.7 0.0 0.5 5.6 16.4 1.3 0.4 0.2 0.3 0.3 1.6 0.3 0.6 0.9 0.7 0.4 0.3 0.9 0.4 0.7 0.1 0.7 1.8 0.2 0.0 0.0 0.0 0.1 0.1 0.1 1.4 0.0 0.0 77.9 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 99.7 0.0 1.3 0.2 0.0 0.2 179.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.6 0.5 0.0 0.0 CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.2;Inhibitory neurons: 354.1;Microglial cells: 126.5;Oligodendrocyte precursor cells: 197.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "basophil: 3.7" "Lineage enriched" "Detected in single" 21 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "HMC-1: 22.7;RPMI-8226: 55.5;SK-BR-3: 10.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" "HPA020215: AB_1845860" "unprognostic (5.85e-2)" "unprognostic (4.90e-3)" "unprognostic (5.09e-2)" "unprognostic (2.24e-2)" "unprognostic (7.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (2.32e-2)" "unprognostic (2.95e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-3)" "unprognostic (1.53e-1)" "prognostic favorable (8.34e-8)" "unprognostic (1.14e-1)" "unprognostic (3.05e-2)" "unprognostic (8.09e-3)" "unprognostic (6.70e-3)" 0.1 6.6 7.0 0.2 4.3 0.7 1.8 2.3 10.4 6.0 0.0 1.5 1.7 3.7 7.3 0.5 7.7 2.0 0.6 3.6 0.8 2.2 1.0 3.7 0.1 0.0 1.2 0.5 2.8 1.2 3.5 0.6 0.4 3.0 1.5 4.3 0.5 1.8 0.2 0.7 2.4 0.7 3.5 1.8 0.8 1.6 6.1 0.2 2.9 0.2 0.1 0.6 0.1 6.0 0.0 0.5 0.1 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 2.7 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.1 0.1 0.0 0.4 0.9 0.0 0.0 0.2 55.5 0.5 3.6 4.7 2.1 0.3 10.1 1.1 0.0 2.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 4.3 2.3 10.4 3.6 0.8 0.0 1.2 0.4 3.5 6.1 6.0 0.6 3.2 36.2 7.8 0.6 0.9 0.8 4.6 2.2 33.3 7.2 1.8 2.3 10.0 9.1 1.8 35.5 0.9 0.5 3.0 0.0 7.2 4.9 4.3 40.1 2.4 59.4 2.7 251.2 2.3 0.2 3.4 5.1 3.3 12.6 1.7 0.0 3.4 0.2 8.4 354.1 3.8 2.0 0.8 4.0 8.3 4.4 2.1 5.4 126.5 0.5 4.0 0.0 197.5 29.9 3.8 5.6 27.1 0.1 1.7 9.5 2.7 9.5 12.9 0.0 0.2 8.6 1.0 3.7 0.5 1.0 0.3 1.7 9.6 7.6 0.9 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNG1 CACNLG ENSG00000108878 "Calcium voltage-gated channel auxiliary subunit gamma 1" Q06432 17 67044554-67056797 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 55 "skeletal muscle: 327.7;tongue: 121.8" "Cell type enriched" "Detected in single" 27 "Skeletal myocytes: 8.1" "Cancer enhanced" "Detected in some" "breast cancer: 1.6;head and neck cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 2.9" "Region enriched" "Detected in single" 6 "basal ganglia: 3.4" "Not detected" "Not detected" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (1.76e-1)" "unprognostic (9.83e-3)" "unprognostic (1.75e-5)" "unprognostic (2.60e-1)" "unprognostic (6.72e-3)" "unprognostic (2.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.84e-3)" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.03e-1)" "unprognostic (1.94e-1)" 0.0 1.6 0.6 0.0 0.7 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 3.3 0.0 327.7 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.6 0.0 121.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.6 0.3 0.2 0.2 0.2 0.2 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.6;placenta: 80.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 146.4;Excitatory neurons: 35.5;Fibroblasts: 39.5;Horizontal cells: 35.3;Inhibitory neurons: 40.5;Muller glia cells: 39.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 65.0;HSkMC: 218.8;hTERT-HME1: 118.5;WM-115: 60.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" NA NA 800000 "Cluster 6: Brain - Smell perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" 17.3 7.9 102.0 15.1 139.6 0.1 9.2 151.6 145.4 27.6 1.2 28.2 4.4 3.9 1.3 11.5 9.2 6.2 18.1 143.1 96.2 2.2 0.6 5.0 14.3 87.4 84.1 1.5 2.2 0.2 31.0 80.6 120.7 5.1 14.4 66.8 5.9 4.7 2.3 13.0 15.8 6.1 66.3 13.3 11.1 3.0 99.4 1.2 7.3 6.5 9.8 16.2 31.0 60.8 0.0 0.0 0.6 0.0 4.2 1.2 0.0 0.0 0.0 9.4 1.8 0.0 0.0 0.1 0.5 0.0 0.1 0.1 0.0 0.0 3.8 0.0 0.0 3.7 0.0 0.0 65.0 0.0 0.2 218.8 0.0 0.1 118.5 0.0 5.3 0.0 0.0 0.2 2.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 4.1 0.0 0.0 5.0 0.0 0.1 9.1 0.0 32.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 60.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.0 139.6 151.6 145.4 143.1 96.2 87.4 84.1 120.7 66.3 99.4 60.8 4.2 0.0 0.5 11.4 0.0 6.6 0.1 0.0 0.6 146.4 0.1 0.8 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.0 0.0 0.2 8.0 0.0 0.0 35.5 0.0 0.8 39.5 0.5 0.0 0.0 0.0 3.6 0.0 1.2 35.3 40.5 0.0 0.0 0.0 10.7 8.3 0.6 0.3 24.9 1.9 0.0 39.4 0.0 18.6 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 9.6 0.0 16.3 3.6 3.1 2.6 0.3 4.3 0.7 0.6 0.0 0.0 0.1 CALHM2 FAM26B ENSG00000138172 "Calcium homeostasis modulator family member 2" Q9HA72 10 103446786-103452402 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 75.1;Fibroblasts: 38.2;Hepatic stellate cells: 48.2;Hofbauer cells: 53.7;Leydig cells: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 45.1;BJ: 37.7;BJ hTERT+: 37.5;fHDF/TERT166: 43.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014706 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" Cytosol "HPA014706: AB_2243916" "unprognostic (2.45e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-1)" "unprognostic (2.48e-1)" "unprognostic (3.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (8.85e-2)" "unprognostic (5.78e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (8.59e-2)" "unprognostic (2.47e-1)" "unprognostic (3.56e-1)" "unprognostic (4.74e-1)" 49.7 18.5 7.2 12.5 6.5 2.1 38.9 6.3 9.0 54.4 7.0 18.4 6.5 58.1 5.5 12.2 43.3 21.6 34.2 7.0 7.3 10.7 4.5 23.2 13.7 8.0 6.4 48.1 7.1 3.1 7.3 10.0 7.8 21.1 4.3 0.4 14.9 10.6 9.7 17.9 19.6 15.9 7.7 35.3 13.8 11.5 8.0 5.6 21.6 11.1 6.1 33.9 39.3 7.9 11.0 7.5 1.8 2.4 27.3 45.1 9.1 37.7 37.5 11.2 15.7 3.3 5.3 3.3 4.2 43.2 0.7 5.0 3.8 0.0 2.1 0.4 21.5 7.8 2.5 0.6 12.4 1.3 0.7 15.6 0.0 3.3 0.1 20.8 13.5 8.3 1.8 19.8 7.5 25.0 3.0 3.7 4.8 2.3 6.7 9.2 3.0 7.5 1.0 0.9 5.3 2.3 1.5 6.2 2.1 0.8 1.2 2.5 24.5 3.6 4.4 12.6 2.7 3.0 7.6 3.8 31.0 24.0 0.8 70.0 91.9 1.8 83.7 178.4 69.6 27.7 56.5 69.7 152.1 7.3 10.8 42.3 3.6 62.9 214.6 17.8 82.7 85.6 7.2 6.5 6.3 9.0 7.0 7.3 8.0 6.4 7.8 7.7 8.0 7.9 18.2 3.2 0.6 1.0 4.9 5.4 2.9 0.6 4.0 0.1 3.4 4.4 3.3 1.5 0.0 3.7 0.0 3.1 11.3 0.1 0.0 4.2 1.0 1.4 19.8 25.5 1.2 5.7 2.3 0.2 75.1 38.2 1.5 2.1 8.8 11.4 48.2 0.6 53.7 0.0 0.5 0.1 2.0 28.8 18.8 2.5 45.7 21.5 8.8 2.8 17.3 0.2 33.0 1.0 0.2 0.1 0.1 16.1 3.1 0.8 0.0 0.3 0.0 0.1 19.7 16.8 27.9 0.8 0.9 0.8 3.8 19.2 19.4 6.0 0.0 1.0 CAMSAP3 "KIAA1543, Nezha, PPP1R80" ENSG00000076826 "Calmodulin regulated spectrin associated protein family member 3" Q9P1Y5 19 7595863-7618304 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 62.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 40.0;Gastric mucus-secreting cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 26.7;Hep G2: 15.6;MCF7: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043830, HPA062149" Enhanced Approved Nucleoplasm,Centrosome NA NA "Cluster 31: Skin - Epidermis development" "Cluster 39: CACO-2 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Centrosome" "HPA043830: AB_10795879, HPA062149: AB_2684698" "unprognostic (3.83e-2)" "unprognostic (1.18e-1)" "unprognostic (8.67e-2)" "unprognostic (7.90e-3)" "unprognostic (3.66e-1)" "unprognostic (3.87e-3)" "unprognostic (7.00e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (1.41e-1)" "prognostic favorable (7.55e-7)" "unprognostic (2.16e-2)" "unprognostic (3.88e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-3)" 0.4 3.3 3.2 0.8 4.4 0.0 5.3 2.5 9.0 7.7 0.1 10.3 14.9 0.5 2.3 24.8 3.1 1.6 0.4 4.2 0.7 12.0 24.3 4.6 0.2 2.5 0.0 0.5 20.6 2.7 8.2 0.4 0.4 10.2 2.4 3.2 18.1 4.5 0.2 62.7 11.5 0.1 0.0 0.6 15.5 13.0 0.2 0.5 11.1 0.0 1.1 3.6 13.4 2.4 11.2 1.8 0.3 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 26.7 5.8 3.1 4.5 0.0 1.2 9.7 4.3 2.8 0.0 2.0 10.1 0.0 0.5 15.6 0.0 0.0 4.4 0.0 5.5 0.0 0.4 0.4 0.0 4.5 0.9 0.0 0.0 13.0 0.2 0.2 6.6 8.4 4.7 0.7 0.0 3.7 1.9 6.0 8.2 8.7 1.3 12.5 0.0 1.6 10.4 1.7 0.0 0.0 2.0 0.0 0.4 5.0 1.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 4.4 2.5 9.0 4.2 0.7 2.5 0.0 0.4 0.0 0.2 2.4 0.2 9.6 19.2 3.3 1.1 9.8 2.7 2.4 3.4 22.7 19.3 12.1 1.5 20.0 5.3 9.2 0.0 0.5 0.2 40.0 3.9 5.7 4.4 9.6 1.4 1.5 13.1 0.0 9.1 11.8 0.7 0.2 38.7 13.5 5.7 8.6 0.4 24.8 0.2 10.1 10.1 22.4 0.0 1.9 1.2 2.9 1.5 1.0 0.0 1.9 0.0 1.5 0.0 4.5 0.6 13.1 28.4 0.0 0.6 6.2 29.2 15.6 2.9 13.4 0.0 0.0 1.1 0.4 2.8 9.8 18.9 0.5 0.9 1.5 18.4 8.0 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.2;stomach 1: 28.5" "Cell type enhanced" "Detected in many" "Club cells: 76.6;Gastric mucus-secreting cells: 50.0;Proximal enterocytes: 35.2;Undifferentiated cells: 18.1;Urothelial cells: 19.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 9.3;SK-BR-3: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.0 0.0 0.8 0.0 1.4 0.0 7.2 0.9 1.3 9.7 1.0 11.4 20.8 0.2 0.3 0.9 1.1 2.8 0.0 0.7 0.8 2.5 0.2 7.2 0.0 1.1 1.3 0.0 3.6 0.4 0.2 0.0 1.0 3.8 24.6 0.0 1.2 0.1 0.0 0.2 29.2 0.2 1.0 0.1 28.5 0.1 1.1 0.0 0.0 0.0 0.6 4.1 0.5 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 9.3 0.1 0.4 0.0 21.9 0.0 0.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.9 1.3 0.7 0.8 1.1 1.3 1.0 1.0 1.1 2.3 0.0 6.4 3.1 0.3 0.0 0.0 10.2 3.5 4.0 0.0 4.2 1.8 1.3 0.0 76.6 1.8 0.0 0.0 0.0 16.9 0.0 1.3 0.8 2.0 0.0 0.1 15.0 0.0 0.3 5.3 0.0 0.6 50.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 1.5 12.0 6.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.4 1.9 6.2 0.0 0.0 2.7 35.2 0.2 12.4 0.0 0.0 0.0 6.1 0.0 0.1 1.4 0.0 0.0 0.1 0.0 18.1 19.4 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1056.7" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 777.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "HSkMC: 13.6" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in all" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" 31.9 3.0 3.5 6.4 2.3 0.0 8.9 2.8 4.0 8.0 2.0 59.8 3.3 17.2 6.5 38.5 14.7 6.6 1056.7 1.8 3.6 3.5 0.6 5.3 0.8 1.9 4.8 5.3 1.2 1.6 0.9 1.6 2.1 13.8 17.0 0.3 7.6 20.2 182.1 4.9 9.1 39.1 1.9 0.8 14.2 1.5 6.4 1.6 4.1 165.0 1.3 43.9 6.9 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 2.3 2.8 4.0 1.8 3.6 1.9 4.8 2.1 1.9 6.4 1.9 2.7 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.6 0.2 0.1 0.4 777.8 0.0 0.0 1.8 0.0 0.4 0.1 0.0 0.0 0.0 15.5 0.3 0.0 4.8 0.0 0.0 0.7 0.0 0.3 17.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 20.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 1.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 92.1 11.0 73.4 0.1 0.4 0.2 0.3 0.0 0.1 0.0 0.0 0.0 CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.3;intestine: 50.9;skin 1: 42.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.6;Pancreatic endocrine cells: 95.0;Paneth cells: 108.1;Proximal enterocytes: 154.6;Undifferentiated cells: 67.1;Urothelial cells: 76.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 43.6;BEWO: 28.9;CACO-2: 28.3;CAPAN-2: 56.9;HaCaT: 41.0;HBEC3-KT: 34.8;hTCEpi: 26.0;OE19: 37.3;RT4: 34.7;SK-BR-3: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" 0.1 0.1 0.0 3.1 0.0 0.0 5.1 0.0 0.1 8.0 0.0 25.0 50.9 0.9 0.1 39.3 2.5 4.4 0.0 0.0 0.0 7.4 21.1 1.3 0.0 0.0 0.0 0.1 20.6 1.6 0.5 0.4 0.0 11.8 11.7 0.1 13.3 2.4 0.1 42.4 38.6 0.6 0.0 0.0 17.7 0.7 0.0 0.3 1.7 0.0 4.0 8.3 18.4 0.0 43.6 0.0 0.0 0.1 0.0 0.0 28.9 0.0 0.0 0.0 0.0 28.3 56.9 0.0 0.0 0.0 0.0 41.0 0.0 34.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 26.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 37.3 0.0 0.0 0.0 0.0 0.0 34.7 0.4 0.1 0.0 31.1 0.0 0.2 22.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 15.0 44.0 30.8 16.5 0.0 9.3 7.4 0.2 4.3 27.7 7.3 0.0 5.8 0.2 108.6 1.9 53.8 0.1 7.0 1.3 0.9 17.4 0.0 0.4 48.9 2.3 0.5 59.7 15.5 0.0 0.0 0.0 11.1 0.3 0.0 0.9 40.0 18.3 0.0 1.4 0.3 0.0 0.4 0.0 0.0 0.6 0.0 0.0 1.0 0.3 95.0 108.1 0.0 0.1 34.4 154.6 17.2 9.8 0.0 0.0 0.0 1.3 0.0 2.6 29.9 25.7 2.5 0.7 0.0 67.1 76.9 CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 114.2;testis: 31.9" "Cell type enhanced" "Detected in some" "Early spermatids: 100.9;Late spermatids: 291.0;Spermatocytes: 61.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "NTERA-2: 40.0;SCLC-21H: 126.0" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in many" 13 "cerebellum: 369.4" "Secreted in brain" NA NA 6000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" 11.8 1.0 4.6 0.2 3.2 0.0 3.8 114.2 7.1 2.1 0.9 0.7 1.0 5.8 0.4 1.0 1.3 7.5 4.6 2.4 23.4 0.2 1.0 0.1 0.8 10.7 18.4 1.3 2.8 0.2 4.2 0.0 12.7 0.5 0.7 3.5 0.6 0.6 0.9 0.8 1.3 1.7 4.8 0.1 0.7 31.9 27.0 0.2 2.3 1.7 2.8 1.4 0.5 5.4 0.0 0.0 0.6 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 2.7 2.6 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 126.0 3.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 3.2 114.2 7.1 2.4 23.4 10.7 18.4 12.7 4.8 27.0 5.4 4.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.3 2.2 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 100.9 0.1 2.4 6.7 13.2 0.0 0.6 0.4 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 4.7 0.5 0.0 0.0 0.0 291.0 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.5 0.4 0.2 0.0 0.4 0.0 0.1 0.3 0.0 0.0 1.8 26.3 0.1 19.2 61.7 5.8 0.0 0.1 0.0 0.0 8.8 0.2 0.0 CCDC201 ENSG00000283247 "Coiled-coil domain containing 201" A0A1B0GTI1 7 45859994-45873082 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 632.7" "Cell type enriched" "Detected in many" 5 "Hepatic stellate cells: 1156.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 41 "HUVEC TERT2: 92.1" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" NA NA 5200000 37000000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" 411.9 102.7 0.4 6.4 0.3 3.3 400.7 0.2 1.7 192.0 2.8 66.6 2.9 198.0 59.3 62.0 233.5 69.3 98.6 0.3 0.3 69.2 82.6 66.4 49.0 0.5 0.3 44.1 22.6 12.4 39.5 0.9 0.7 97.4 9.8 0.0 61.9 49.5 55.9 93.3 50.5 94.3 0.4 632.7 67.5 16.0 0.4 34.4 123.9 24.5 28.2 116.8 177.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 92.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.7 0.3 0.3 0.5 0.3 0.7 0.4 0.4 0.3 136.5 0.0 8.2 0.0 2.2 1.9 0.1 0.0 3.4 0.0 0.6 1.1 0.2 18.6 0.6 0.0 0.0 0.0 0.1 2.0 0.0 0.0 24.2 0.4 0.3 203.8 0.0 26.7 0.0 0.0 0.0 9.4 0.0 0.2 1.3 0.0 1156.5 11.0 0.3 0.0 0.0 1.0 0.0 58.8 3.1 63.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.2 2.3 1.1 2.6 0.0 0.0 0.3 2.3 0.0 0.0 2.0 1.4 0.0 1.8 0.1 0.6 0.2 CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 48.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 189.1;Langerhans cells: 104.3;Macrophages: 153.1" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 55500000 6400000 "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" 9.7 0.3 0.0 2.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 2.0 3.9 0.1 0.0 0.9 0.4 0.0 1.6 0.0 0.0 0.2 0.3 48.7 7.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.7 0.0 2.5 0.0 0.0 0.9 9.2 1.5 0.0 4.0 0.2 0.5 0.1 6.1 1.1 0.0 5.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 25.4 0.0 1.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 13.6 0.0 0.0 0.5 4.2 0.0 0.0 0.0 24.5 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.0 5.1 0.0 0.4 0.7 189.1 0.0 0.0 0.0 0.0 4.2 104.3 5.3 0.0 153.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.4 0.9 0.0 0.1 0.1 3.4 1.6 2.9 0.0 0.0 0.0 CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.7;lung: 35.8;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in many" "dendritic cells: 441.4;Hofbauer cells: 2084.4;Kupffer cells: 723.2;Langerhans cells: 710.0;Macrophages: 1534.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.6" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.6" "Cell line enhanced" "Detected in some" "Karpas-707: 443.8;U-266/70: 602.5;U-266/84: 2043.3" "Secreted to blood" NA NA 138000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" 17.6 16.0 0.0 8.1 0.7 76.7 5.6 0.0 1.4 1.5 0.0 2.5 0.0 1.1 0.0 0.5 2.9 10.3 3.7 0.0 0.0 4.6 12.9 35.8 1.8 0.7 0.0 1.2 1.3 0.0 1.7 2.4 0.0 2.2 0.0 0.0 5.6 0.0 0.8 0.8 3.1 0.0 0.0 49.4 3.0 0.7 0.5 0.0 2.0 0.0 0.0 3.0 1.4 1.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.8 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 55.6 0.0 0.0 1.3 602.5 2043.3 0.0 0.0 0.0 0.0 0.0 2.1 10.8 23.6 1.3 0.0 5.1 0.0 6.1 0.4 10.4 0.1 6.8 10.5 3.5 1.3 0.0 0.0 11.6 0.0 0.7 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.5 1.4 33.0 0.0 28.6 0.0 45.3 27.9 2.0 0.2 1.2 1.8 23.1 50.0 2.2 4.3 4.4 0.0 0.0 19.0 441.4 0.7 0.0 0.6 1.5 1.6 2.5 115.9 0.0 61.9 0.0 0.2 22.6 14.5 2.0 2.8 23.5 0.1 27.1 9.1 2084.4 0.0 0.0 0.5 0.0 723.2 710.0 1.9 1.8 1534.2 94.3 2.8 23.5 2.1 106.1 0.0 0.0 0.4 0.0 0.0 344.8 1.2 0.0 0.9 2.2 3.7 6.6 2.3 9.2 0.5 0.6 0.6 28.8 54.3 248.0 0.1 0.2 1.3 CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9" "Cell type enhanced" "Detected in many" "dendritic cells: 3753.7;Hofbauer cells: 849.7;Macrophages: 1168.2;NK-cells: 1232.8;Plasma cells: 974.5;T-cells: 1948.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 414.7" "Group enriched" "Detected in all" 6 "granulocytes: 135.0;T-cells: 414.7" "Group enriched" "Detected in some" 6 "U-266/70: 51.6;U-266/84: 13.3" CAB007805 Approved "Secreted to blood" NA NA 144000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" 38.9 28.0 2.0 32.0 2.0 192.9 10.5 3.4 5.5 16.0 4.1 9.9 7.6 10.3 6.4 15.0 8.2 45.1 4.4 2.0 1.9 6.8 84.2 33.9 34.3 3.2 2.9 5.0 15.6 12.0 2.5 17.8 2.8 7.6 11.1 0.1 5.1 3.4 1.0 0.9 11.4 18.0 2.5 65.3 10.3 2.7 2.1 24.1 5.9 4.5 15.4 56.4 4.4 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 51.6 13.3 0.2 0.2 0.1 0.0 14.4 3.4 135.0 414.7 4.8 101.6 8.4 46.0 240.6 2.3 17.7 13.8 181.7 55.8 42.8 11.1 2.6 0.5 138.9 2.0 2.0 3.4 5.5 2.0 1.9 3.2 2.9 2.8 2.5 2.1 3.3 52.3 0.0 54.5 0.0 135.9 15.6 1.9 0.3 24.5 1.5 26.3 49.3 11.2 14.3 7.2 0.0 0.0 9.7 3753.7 1.2 0.0 0.4 20.8 3.7 4.7 77.6 1.2 60.9 0.0 0.4 11.3 18.9 118.3 5.5 60.8 0.2 21.4 10.5 849.7 1.7 0.0 1.5 0.0 429.4 428.0 32.6 0.9 1168.2 51.6 3.7 10.5 1.1 1232.8 0.0 0.0 0.2 0.1 0.4 974.5 0.8 0.4 2.8 5.8 5.2 0.0 3.9 20.9 0.4 0.4 11.0 14.5 25.9 1948.3 0.0 0.9 1.6 CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.2;lymphoid tissue: 20.5" "Group enriched" "Detected in many" 6 "dendritic cells: 488.0;Hofbauer cells: 358.5;Kupffer cells: 163.4;Macrophages: 585.2;NK-cells: 249.3;T-cells: 303.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.0" "Group enriched" "Detected in some" 4 "Daudi: 4.1;HMC-1: 5.6;U-266/70: 8.8" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (3.82e-1)" "unprognostic (3.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (1.99e-3)" 5.5 3.8 0.3 4.4 0.3 32.2 1.5 0.5 1.1 0.9 0.4 1.7 1.5 1.1 0.5 0.7 2.6 6.8 1.3 0.4 0.3 3.1 7.6 12.6 3.2 0.3 0.3 1.9 0.9 2.0 1.1 2.2 0.3 1.9 1.8 0.0 2.0 0.7 0.2 0.4 3.8 1.5 0.3 20.5 1.8 0.2 0.3 1.6 1.4 1.7 0.8 4.8 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.8 1.5 0.7 0.0 0.0 0.0 0.6 0.3 122.0 15.2 0.3 3.6 0.0 0.6 8.9 0.1 0.1 0.1 8.4 18.2 1.2 0.2 0.0 0.0 5.5 0.3 0.3 0.5 1.1 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.4 18.1 0.0 7.7 0.7 13.9 0.4 0.4 0.0 5.7 0.4 13.8 22.9 8.6 4.3 0.0 0.0 0.0 4.2 488.0 0.2 0.0 0.1 0.2 0.4 1.0 38.1 0.0 14.3 1.1 0.0 6.1 3.9 3.1 0.8 5.1 8.2 7.1 1.3 358.5 1.7 0.4 0.1 0.0 163.4 59.1 1.2 0.0 585.2 1.8 6.5 3.3 1.3 249.3 0.0 0.1 0.1 0.1 0.0 50.6 0.4 0.0 0.2 0.0 2.3 13.1 1.1 6.6 0.1 0.1 1.4 0.4 9.6 303.6 0.1 0.0 1.8 CCM2 "C7orf22, MGC4607, OSM" ENSG00000136280 "CCM2 scaffold protein" Q9BSQ5 7 44999475-45076469 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 140.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020273, HPA021669, HPA065815" Supported Enhanced Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA020273: AB_1846185, HPA021669: AB_1846186, HPA065815: AB_2685562" "unprognostic (4.30e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (4.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.37e-3)" "unprognostic (3.92e-1)" "unprognostic (2.65e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.03e-1)" "prognostic unfavorable (5.06e-7)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (2.81e-2)" "unprognostic (2.48e-1)" 32.7 40.7 62.5 25.1 74.5 15.5 26.6 58.7 89.1 19.1 48.4 30.2 13.2 20.3 6.4 22.4 18.9 11.5 37.1 63.0 62.4 24.2 86.0 29.2 43.6 67.6 62.8 16.1 26.6 21.4 30.4 14.5 69.2 23.8 10.8 9.4 18.8 14.5 48.2 21.1 27.6 16.9 60.0 54.6 24.0 30.3 71.5 45.4 18.7 36.9 29.6 27.2 20.0 68.6 38.7 41.8 24.4 49.2 45.5 39.8 17.7 45.9 37.3 32.0 43.3 30.6 39.3 53.7 34.5 58.5 101.8 49.5 15.3 58.9 21.4 61.0 29.7 23.3 34.0 22.1 39.9 9.9 61.5 44.7 38.0 56.3 24.0 30.0 59.2 76.8 27.5 42.1 64.7 58.2 47.9 131.6 28.4 32.3 46.1 25.7 14.2 43.9 33.1 36.8 46.9 36.8 37.5 29.2 20.9 31.7 33.3 45.7 45.1 43.4 36.4 44.2 44.8 75.9 64.0 109.2 42.3 35.7 53.4 108.1 33.5 105.8 52.2 40.2 35.2 42.0 62.3 57.4 23.6 43.6 58.9 44.1 103.9 60.9 47.7 23.8 167.1 40.2 62.5 74.5 58.7 89.1 63.0 62.4 67.6 62.8 69.2 60.0 71.5 68.6 28.7 19.2 19.4 26.1 57.5 46.8 22.6 27.6 54.7 19.0 13.5 24.6 13.0 20.0 18.8 14.7 4.2 28.3 53.7 30.5 25.4 30.2 6.9 6.0 14.3 26.7 15.6 13.7 33.3 38.5 35.8 25.0 11.2 7.4 36.1 23.8 30.4 56.5 49.3 82.4 24.9 15.2 12.2 47.9 51.1 12.8 21.1 47.7 33.8 56.2 140.0 34.1 122.6 20.1 51.7 45.3 11.4 20.3 69.1 40.4 13.6 22.9 8.0 14.4 19.7 16.2 29.6 15.3 37.8 16.8 23.0 10.4 55.7 36.9 15.2 19.7 CCND3 ENSG00000112576 "Cyclin D3" P30281 6 41934934-42050357 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 256.6" "Cell type enhanced" "Detected in all" "NK-cells: 555.1;Syncytiotrophoblasts: 236.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 696.3;REH: 651.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000116, HPA042871" Approved Supported Nucleoplasm NA Yes "Cluster 10: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "CAB000116: , HPA042871: " "unprognostic (4.53e-2)" "unprognostic (4.45e-2)" "unprognostic (2.45e-1)" "unprognostic (4.40e-3)" "unprognostic (1.01e-1)" "unprognostic (9.80e-2)" "unprognostic (3.40e-2)" "unprognostic (5.25e-2)" "unprognostic (7.76e-2)" "unprognostic (3.45e-1)" "unprognostic (9.17e-2)" "unprognostic (6.39e-2)" "unprognostic (2.45e-3)" "unprognostic (9.12e-2)" "unprognostic (1.71e-1)" "prognostic favorable (8.08e-6)" "unprognostic (2.11e-1)" 74.3 137.6 84.8 63.1 84.6 220.2 64.8 80.0 94.5 36.9 78.4 45.6 40.6 35.4 15.3 39.6 43.2 34.4 68.1 86.2 88.6 42.4 22.1 102.5 143.3 87.4 82.5 36.0 31.6 23.7 33.3 55.4 84.0 50.4 27.0 10.3 50.4 25.6 18.2 52.3 78.5 28.6 79.7 170.4 66.1 11.1 86.4 256.6 58.7 32.5 83.6 45.4 44.3 80.8 67.7 242.2 24.6 54.8 43.7 88.6 286.1 77.1 43.7 77.7 57.1 45.9 29.7 288.9 127.8 51.9 68.9 40.5 65.8 93.4 39.2 49.2 43.4 458.8 106.6 37.3 94.9 75.9 385.2 84.7 59.8 76.0 27.9 23.5 96.6 188.3 236.7 27.2 111.6 92.0 696.3 354.6 10.9 202.8 51.5 651.8 96.3 32.2 179.1 44.9 83.8 21.8 65.8 83.3 38.6 30.6 51.5 288.4 162.9 86.2 47.9 74.7 88.1 17.9 15.2 458.5 50.4 157.6 53.3 1281.3 246.3 725.1 390.4 294.4 276.5 127.1 266.4 318.1 343.3 180.8 306.4 328.3 339.3 333.2 405.6 221.4 193.0 635.4 84.8 84.6 80.0 94.5 86.2 88.6 87.4 82.5 84.0 79.7 86.4 80.8 102.2 60.9 67.9 31.0 102.9 27.0 95.8 52.3 48.9 19.6 49.9 45.1 26.2 64.3 27.8 20.2 6.2 201.0 227.3 66.4 29.4 20.3 12.8 12.1 10.8 68.3 9.6 133.6 37.1 24.3 82.4 32.3 19.9 11.2 26.6 7.7 70.6 7.2 45.3 11.8 23.7 19.5 50.8 115.7 51.7 9.4 41.3 152.2 37.4 47.8 79.0 40.8 555.1 18.1 9.3 29.9 30.5 51.9 48.7 40.3 18.6 19.8 22.5 16.2 46.0 19.2 31.9 4.3 6.3 21.7 22.6 236.6 195.0 141.6 32.7 52.8 CCNO "CCNU, FLJ22422, UDG2, UNG2" ENSG00000152669 "Cyclin O" P22674 5 55231152-55233608 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" Cyclin "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.3;pancreas: 10.1;testis: 13.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.3;Club cells: 51.4;Collecting duct cells: 33.1;Endometrial ciliated cells: 38.1;Ionocytes: 61.1;Respiratory ciliated cells: 97.2;Spermatocytes: 53.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 5.2;T-47d: 7.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA050090 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA050090: AB_2681011" "unprognostic (3.44e-2)" "unprognostic (5.20e-2)" "unprognostic (5.28e-2)" "prognostic favorable (6.78e-4)" "unprognostic (3.96e-2)" "unprognostic (2.60e-1)" "unprognostic (3.18e-3)" "prognostic favorable (7.60e-4)" "unprognostic (3.54e-2)" "unprognostic (2.10e-1)" "unprognostic (1.92e-1)" "unprognostic (3.09e-1)" "unprognostic (3.03e-2)" "prognostic favorable (5.10e-4)" "unprognostic (1.81e-1)" "unprognostic (9.49e-2)" "unprognostic (8.88e-3)" 0.1 0.4 1.3 0.0 2.8 0.0 0.5 1.1 2.3 1.0 12.3 0.3 0.3 0.2 0.3 1.0 2.1 0.1 0.1 2.2 1.8 1.9 0.2 1.3 0.0 1.7 1.9 0.8 10.1 1.1 5.3 0.1 1.1 2.0 0.0 0.1 1.8 1.2 0.0 1.8 0.5 0.0 1.2 0.0 5.6 13.2 2.0 0.0 5.5 0.0 0.0 1.8 0.4 1.3 2.8 3.2 0.0 1.6 0.2 0.0 5.2 0.0 0.0 0.4 0.5 0.0 3.1 0.0 2.0 0.0 1.0 2.6 0.1 0.0 0.0 0.0 4.1 0.1 3.5 0.3 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.4 0.0 1.3 0.1 0.0 0.0 2.7 0.0 0.1 0.2 0.4 4.4 1.5 0.3 0.0 1.2 1.0 1.9 0.0 3.5 0.8 1.1 0.0 7.5 0.5 0.2 0.0 2.2 2.8 1.2 2.6 1.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.8 1.1 2.3 2.2 1.8 1.7 1.9 1.1 1.2 2.0 1.3 0.2 0.0 1.5 0.7 0.0 1.0 3.7 39.3 5.7 11.9 9.2 5.0 0.5 2.8 51.4 33.1 6.2 0.7 0.3 2.7 0.0 4.2 12.5 38.1 0.5 0.3 0.0 0.0 2.8 28.5 1.9 0.6 13.3 5.4 0.0 0.1 0.0 0.0 0.1 1.7 0.3 3.4 61.1 0.0 0.7 4.4 1.2 0.2 1.8 0.0 0.0 0.1 0.0 0.5 0.1 11.1 2.7 0.4 0.0 7.9 5.7 1.0 97.2 0.5 0.0 0.3 5.1 53.9 21.5 3.3 2.4 0.3 0.2 0.0 4.2 5.9 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD200 "MOX1, MOX2, MRC, OX-2" ENSG00000091972 "CD200 molecule" P41217 3 112332347-112362812 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 97.4;Excitatory neurons: 54.5;Inhibitory neurons: 55.7;Syncytiotrophoblasts: 75.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "memory B-cell: 30.7;naive B-cell: 83.6" "Lineage enriched" "Detected in many" 23 "B-cells: 83.6" "Cell line enhanced" "Detected in some" "AF22: 75.9;HHSteC: 27.2;NTERA-2: 47.7;REH: 42.4;SK-MEL-30: 29.8;WM-115: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031149 Approved NA NA 26000 "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA031149: AB_10600694" "unprognostic (1.84e-1)" "unprognostic (5.08e-2)" "unprognostic (1.79e-1)" "unprognostic (2.03e-3)" "unprognostic (4.97e-1)" "unprognostic (1.21e-2)" "unprognostic (9.29e-2)" "unprognostic (2.25e-2)" "unprognostic (3.06e-1)" "unprognostic (3.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.06e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (1.22e-2)" 25.3 12.1 27.7 15.6 27.3 2.4 11.6 13.2 34.0 20.1 2.9 6.7 3.3 28.4 7.1 8.9 26.7 13.1 9.3 27.9 41.3 8.5 1.0 9.6 26.1 11.9 16.3 11.6 4.9 10.5 26.8 28.2 18.8 12.1 8.2 15.1 9.0 16.5 1.8 4.4 6.9 18.3 15.1 6.2 5.2 2.9 30.4 23.6 18.9 3.6 24.9 27.5 5.9 18.3 0.0 0.0 75.9 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 0.2 4.1 0.0 0.9 0.1 8.2 0.4 0.2 0.2 0.5 0.0 0.3 0.4 27.2 0.0 0.1 0.5 0.2 1.6 0.2 0.2 10.8 0.0 0.1 0.7 0.2 0.0 1.2 0.0 47.7 0.0 0.0 42.4 0.1 0.5 0.6 0.1 19.9 23.0 0.0 0.4 29.8 14.0 0.0 0.3 0.1 0.3 2.6 0.0 0.2 0.1 0.1 0.0 0.6 0.2 83.7 3.6 0.4 0.3 0.3 0.1 3.5 30.7 2.0 0.6 1.3 83.6 2.1 1.3 1.7 1.6 0.3 2.8 1.0 3.4 27.7 27.3 13.2 34.0 27.9 41.3 11.9 16.3 18.8 15.1 30.4 18.3 15.2 3.2 9.1 10.7 27.8 4.2 12.6 0.3 0.0 26.8 0.7 13.0 0.8 1.5 1.3 1.8 0.0 3.0 1.6 0.8 0.0 0.3 25.1 20.6 4.2 97.4 38.4 0.8 54.5 0.0 12.1 13.0 3.1 41.0 2.5 0.7 1.4 0.0 1.0 3.3 55.7 8.1 0.0 0.3 6.1 30.3 0.3 1.1 8.8 6.5 14.0 7.1 0.0 29.7 38.5 0.2 10.7 0.0 1.9 15.4 0.9 0.3 2.7 2.5 0.0 13.1 2.6 0.6 0.4 0.7 3.3 75.9 2.9 9.3 7.1 21.6 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CDC42EP2 "BORG1, CEP2" ENSG00000149798 "CDC42 effector protein 2" O14613 11 65314866-65322417 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 50.5;Langerhans cells: 77.7;Pancreatic endocrine cells: 65.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 50.4;intermediate monocyte: 118.8;neutrophil: 171.5;non-classical monocyte: 88.5" "Group enriched" "Detected in many" 15 "granulocytes: 171.5;monocytes: 118.8" "Cell line enhanced" "Detected in many" "HHSteC: 51.5;PC-3: 61.0;U-2197: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038562 Approved Supported Microtubules,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Microtubules, Cytosol" "HPA038562: AB_10671745" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (4.73e-3)" "prognostic unfavorable (2.89e-5)" "prognostic unfavorable (6.66e-4)" "unprognostic (1.01e-1)" "unprognostic (5.36e-2)" "unprognostic (8.57e-3)" "unprognostic (3.81e-1)" "unprognostic (1.68e-1)" "unprognostic (2.66e-2)" "unprognostic (3.67e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-2)" 42.1 5.7 15.4 7.7 25.1 0.4 23.1 20.7 20.0 13.9 5.8 15.4 9.1 16.6 1.7 7.7 15.3 15.2 22.4 15.7 17.0 15.3 4.1 19.1 1.8 24.9 23.6 10.8 5.8 0.6 5.0 11.6 22.3 10.2 1.6 1.9 4.9 4.5 6.6 5.6 13.0 6.8 17.5 18.4 14.5 2.1 21.4 0.4 16.8 5.6 1.2 18.6 9.4 44.3 7.1 6.6 0.9 4.3 14.6 26.4 1.3 7.4 28.8 5.5 6.2 19.8 16.7 0.5 20.9 19.9 2.0 8.9 2.5 26.0 1.2 1.0 3.8 1.3 12.8 14.8 51.5 0.4 0.5 11.5 2.7 20.3 28.8 4.5 22.4 1.0 2.6 4.3 7.1 10.7 0.8 1.6 3.7 18.5 61.0 0.8 0.7 0.5 19.5 4.9 0.5 1.7 18.0 14.7 1.1 0.7 2.5 0.4 30.6 6.7 5.6 55.9 3.1 0.1 1.7 0.6 11.2 0.3 2.7 0.0 50.4 2.1 0.1 118.8 0.1 1.2 0.0 0.1 9.9 0.0 0.1 0.0 171.5 0.0 88.5 0.4 0.0 17.8 15.4 25.1 20.7 20.0 15.7 17.0 24.9 23.6 22.3 17.5 21.4 44.3 25.8 0.0 0.0 0.0 1.5 12.7 11.0 25.8 6.8 15.3 12.1 6.3 6.3 2.8 17.0 12.9 0.0 0.5 1.6 10.0 3.9 50.5 0.5 6.0 11.6 36.4 1.8 2.7 0.6 40.3 3.5 32.3 9.7 11.1 5.7 1.5 26.7 0.9 1.3 3.3 0.4 8.0 8.2 18.7 77.7 1.9 18.6 33.3 12.4 1.0 18.3 1.0 0.0 0.0 10.6 65.1 15.6 13.5 1.8 7.4 21.2 3.7 6.3 5.3 39.5 16.6 16.2 1.7 3.4 4.8 10.1 1.6 1.4 1.8 8.4 36.4 CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687337 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 74.5" "Group enriched" "Detected in many" 9 "B-cells: 20.7;dendritic cells: 21.5;monocytes: 74.5" "Cell line enhanced" "Detected in many" "HHSteC: 798.5;HSkMC: 586.5;hTCEpi: 775.8;LHCN-M2: 604.2" "Region enhanced" "Detected in all" "olfactory bulb: 76.0" "Low region specificity" "Detected in all" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: AB_1620493, HPA005946: AB_2667477" "unprognostic (7.99e-3)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "prognostic favorable (3.14e-5)" "unprognostic (1.57e-2)" "unprognostic (2.19e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.30e-1)" "unprognostic (7.27e-2)" "unprognostic (2.79e-2)" "unprognostic (7.55e-3)" "prognostic favorable (4.95e-5)" "unprognostic (8.32e-2)" "unprognostic (6.52e-2)" "unprognostic (1.12e-1)" "unprognostic (3.21e-2)" 322.1 98.1 47.0 62.1 48.1 72.7 144.2 47.3 60.9 123.3 85.9 119.0 115.2 74.4 41.0 203.2 213.9 132.6 170.6 47.2 49.5 149.9 173.4 182.2 17.3 63.7 54.6 184.9 130.5 70.1 104.4 44.7 53.4 91.4 108.2 29.2 79.1 29.4 241.6 224.4 130.0 114.3 55.0 34.4 121.3 47.0 50.3 59.7 77.5 26.9 21.8 212.7 142.3 53.6 27.0 108.1 80.1 2.0 273.3 490.3 149.5 435.6 344.8 52.3 203.7 9.6 25.3 18.3 15.5 267.9 48.0 60.2 3.7 477.7 82.4 36.2 22.0 3.0 85.8 137.0 798.5 0.5 127.7 586.5 775.8 476.2 147.1 309.3 275.3 1.4 5.1 120.8 604.2 57.4 3.9 11.3 10.2 112.8 15.5 54.4 67.1 31.9 91.2 201.5 36.7 35.6 101.3 8.4 21.3 185.2 32.7 111.2 155.8 91.5 86.9 6.2 36.4 202.0 42.9 54.5 118.7 9.9 261.0 0.0 22.8 0.5 0.5 52.2 0.8 20.7 1.1 0.6 20.0 16.2 0.3 0.4 4.2 0.7 74.5 21.5 2.9 34.2 47.0 48.1 47.3 60.9 47.2 49.5 63.7 54.6 53.4 55.0 50.3 53.6 571.2 83.3 45.1 1.0 126.9 440.5 340.1 293.1 512.8 0.8 203.9 187.6 151.6 41.5 214.4 68.0 0.0 42.1 56.4 505.3 46.9 217.6 0.9 227.9 57.3 327.1 175.5 5.7 0.5 264.7 52.8 302.4 150.9 199.2 104.4 20.4 71.7 68.9 72.9 0.0 0.4 197.1 156.6 62.0 556.0 3.9 34.5 277.6 218.7 5.6 280.6 58.4 2.1 0.0 0.5 429.9 466.1 16.6 376.4 201.7 383.2 17.2 215.1 3.1 26.3 303.6 471.6 1.2 1.7 620.9 672.0 155.3 106.0 10.7 75.8 478.0 CDON "CDO, CDON1, ORCAM" ENSG00000064309 "Cell adhesion associated, oncogene regulated" Q4KMG0 11 125955796-126063335 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 58.3;Fibroblasts: 23.5;Inhibitory neurons: 49.5;Muller glia cells: 39.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "cerebellum: 23.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 28.4;ASC diff: 32.7;RH-30: 48.9;SuSa: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB012422, HPA017377" Uncertain NA NA 15000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB012422: AB_2260246, HPA017377: AB_1846453" "prognostic favorable (1.35e-4)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.25e-4)" "unprognostic (1.10e-1)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (5.77e-3)" "unprognostic (2.78e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (5.39e-2)" "unprognostic (1.51e-1)" "unprognostic (5.83e-3)" "unprognostic (1.86e-4)" 12.6 0.7 1.9 1.6 2.0 0.0 5.1 23.0 4.0 7.9 1.2 12.4 1.0 14.0 2.1 1.7 14.2 4.8 4.0 1.6 1.8 0.8 1.2 2.7 1.1 2.2 1.9 20.6 1.2 2.5 3.0 2.7 2.7 1.3 1.6 10.1 1.7 2.8 1.2 9.9 2.9 17.0 0.5 0.7 4.6 3.6 2.3 2.8 18.5 1.6 1.5 2.5 3.0 2.1 1.6 3.2 28.4 2.8 32.7 14.5 0.4 0.5 2.9 0.9 0.3 1.1 9.4 1.4 6.8 0.6 3.3 0.4 7.1 1.0 0.8 5.5 6.3 0.5 6.5 2.9 6.4 0.4 1.8 4.5 1.2 0.6 0.0 12.2 0.3 4.8 0.1 1.9 2.7 0.4 3.6 1.0 2.6 0.8 3.7 1.1 48.9 0.9 1.7 0.5 2.4 9.6 3.7 0.3 4.7 23.8 2.4 1.0 0.5 3.2 2.2 6.3 3.3 2.5 5.5 0.2 2.0 1.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.0 23.0 4.0 1.6 1.8 2.2 1.9 2.7 0.5 2.3 2.1 3.0 6.4 9.9 11.1 0.1 15.2 1.4 0.8 2.2 5.1 5.4 1.9 5.2 2.8 5.6 0.0 16.7 0.6 0.1 0.2 0.0 1.3 3.1 1.7 0.5 3.0 7.7 0.4 58.3 0.6 0.4 23.5 1.5 1.1 0.0 1.8 1.1 2.1 0.3 0.0 49.5 0.3 0.0 0.0 7.6 2.7 14.9 0.2 3.6 2.8 0.1 39.3 0.0 14.1 5.8 2.4 0.4 11.3 0.8 1.1 0.6 0.5 4.2 4.6 0.0 2.9 2.7 1.8 3.8 0.5 10.7 0.7 0.6 13.2 0.4 1.6 CDR2 "CDR62, Yo" ENSG00000140743 "Cerebellar degeneration related protein 2" Q01850 16 22345936-22437165 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 70.2;Spermatocytes: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 8.4;NK-cells: 2.5;T-cells: 6.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018151, HPA023870" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA018151: AB_1846457, HPA023870: AB_1846459" "unprognostic (7.89e-2)" "unprognostic (1.55e-1)" "unprognostic (5.23e-2)" "unprognostic (3.09e-1)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (2.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.06e-1)" "unprognostic (9.86e-2)" "unprognostic (3.04e-1)" "unprognostic (2.04e-2)" "unprognostic (3.34e-3)" "unprognostic (1.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.67e-3)" 19.1 12.0 9.5 19.0 17.7 23.9 14.6 13.6 10.9 18.8 32.0 22.5 28.6 17.8 10.3 12.1 15.9 22.2 14.3 9.8 9.5 25.0 22.9 21.6 25.4 8.6 7.6 14.9 13.9 13.2 21.8 15.0 8.5 20.7 19.3 74.0 15.7 23.1 5.9 10.6 22.1 27.2 5.0 18.7 17.5 62.0 10.5 28.2 49.0 5.6 19.3 29.2 14.0 8.3 38.9 26.8 22.8 24.2 55.2 47.4 23.9 36.4 57.0 36.7 48.4 35.3 25.9 33.3 19.3 62.4 22.2 36.5 49.2 20.8 43.0 26.2 25.1 25.3 29.4 111.0 63.4 27.6 49.6 35.6 18.8 36.2 40.3 46.3 46.2 42.6 25.1 53.3 35.4 28.0 27.8 20.0 32.4 32.3 22.0 40.1 29.4 49.5 45.7 24.8 17.5 12.5 24.8 51.9 36.4 25.7 15.4 13.7 31.9 36.2 22.9 34.5 32.9 27.6 49.7 46.9 23.8 27.1 31.7 8.4 0.8 1.2 1.6 0.7 3.6 0.9 5.3 3.4 0.9 0.6 4.1 3.5 0.7 2.5 0.9 1.1 6.5 1.7 9.5 17.7 13.6 10.9 9.8 9.5 8.6 7.6 8.5 5.0 10.5 8.3 18.2 3.2 5.1 3.6 8.7 34.0 17.3 4.3 15.4 8.9 27.4 9.1 3.5 10.0 7.0 9.2 14.6 1.7 12.7 22.0 1.9 8.7 36.7 6.9 10.0 13.9 6.6 17.2 8.0 7.1 10.8 19.6 19.4 12.0 0.0 9.6 10.0 9.5 9.4 8.4 10.5 16.1 6.1 5.0 11.5 8.8 6.8 7.4 10.6 2.8 4.0 10.1 4.1 3.5 2.2 13.8 12.2 10.9 24.9 19.4 22.4 12.4 4.9 70.2 6.6 9.7 15.8 50.9 16.1 8.7 24.3 1.4 25.8 2.7 7.8 14.8 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.2;liver: 52.5;skeletal muscle: 24.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 120.1;Granulosa cells: 58.5;Hepatocytes: 53.4;Intestinal goblet cells: 32.0;Paneth cells: 67.0;Proximal enterocytes: 66.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 7.4;Daudi: 8.5;JURKAT: 13.5;U-937: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" NA NA 1200000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" 0.8 0.5 3.1 3.2 2.7 0.9 2.3 2.5 2.9 1.3 1.3 38.2 30.0 0.7 0.2 4.2 2.9 0.9 0.7 3.8 2.0 12.2 52.5 0.7 0.3 3.3 2.7 0.6 4.1 1.0 1.9 0.6 3.5 0.5 31.3 0.6 12.0 0.3 24.7 1.2 23.7 1.2 1.4 0.4 7.7 1.1 2.2 0.2 0.4 1.5 0.2 0.1 0.8 2.2 0.4 3.1 0.3 7.4 0.2 0.2 1.2 0.2 0.2 0.3 0.5 0.5 3.8 8.5 2.4 0.0 0.2 0.6 1.1 0.5 0.1 1.5 5.5 4.3 1.3 2.6 0.0 0.9 0.7 0.3 0.9 0.8 0.1 0.2 0.0 13.5 2.8 1.7 0.3 1.1 1.4 1.4 1.5 2.6 0.4 1.3 0.7 1.3 0.1 0.4 0.4 0.8 0.2 5.8 0.2 0.6 5.0 6.5 0.3 0.4 2.4 0.7 0.2 0.9 3.6 1.3 0.3 7.2 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 3.1 2.7 2.5 2.9 3.8 2.0 3.3 2.7 3.5 1.4 2.2 2.2 0.1 3.2 6.7 0.7 0.4 0.5 0.0 1.3 1.2 0.2 9.1 5.7 1.4 2.8 0.9 0.0 0.0 0.0 0.0 120.1 0.0 0.2 0.5 3.2 0.3 0.2 19.7 0.0 1.8 0.9 0.0 0.2 11.7 4.4 1.3 58.5 0.4 53.4 0.3 0.0 2.9 32.0 0.0 3.2 0.9 5.4 0.0 0.9 0.0 0.0 0.0 0.4 0.0 1.5 0.1 1.0 67.0 1.2 0.1 0.1 66.0 9.9 4.8 0.2 0.0 0.6 0.2 2.3 2.9 1.1 0.3 0.0 0.4 0.1 44.3 0.2 CFAP46 "bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40" ENSG00000171811 "Cilia and flagella associated protein 46" Q8IYW2 10 132808392-132942823 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 22.5;skeletal muscle: 33.4;testis: 41.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.9;Endometrial ciliated cells: 70.8;Excitatory neurons: 42.8;Respiratory ciliated cells: 59.0;Rod photoreceptor cells: 74.4;Spermatocytes: 53.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037786, HPA038034, HPA038867, HPA038868" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA037786: AB_10672392, HPA038034: AB_2675796, HPA038867: AB_2676246, HPA038868: AB_2676247" "unprognostic (2.83e-2)" "unprognostic (4.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.19e-2)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-1)" "unprognostic (4.11e-1)" "unprognostic (5.40e-2)" "unprognostic (6.41e-3)" "unprognostic (1.39e-1)" "unprognostic (1.64e-4)" "unprognostic (1.21e-2)" "unprognostic (8.08e-2)" "unprognostic (4.56e-3)" "unprognostic (2.08e-2)" 0.0 0.2 5.9 0.0 7.0 0.0 0.1 4.2 10.0 1.5 22.5 0.0 0.1 0.1 1.3 0.2 16.1 0.1 0.7 6.5 6.1 1.0 0.2 3.4 0.0 13.5 17.3 0.2 0.4 1.1 2.2 0.0 8.5 0.2 0.0 3.9 0.4 0.4 33.4 0.1 0.1 0.0 9.4 0.1 2.4 41.8 6.6 0.0 4.2 10.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 5.9 7.0 4.2 10.0 6.5 6.1 13.5 17.3 8.5 9.4 6.6 4.6 0.2 0.0 4.8 9.8 0.3 0.0 0.5 0.0 0.6 6.3 1.3 1.1 3.7 0.0 9.3 7.3 95.9 0.0 0.0 0.0 5.9 4.8 18.0 70.8 0.9 0.9 0.0 0.0 42.8 0.2 0.0 1.5 5.1 1.5 3.8 4.3 5.0 0.2 0.6 1.7 22.0 0.0 0.0 0.6 0.0 11.3 1.2 0.3 0.0 1.0 0.0 4.7 0.0 2.0 0.9 1.6 0.0 2.2 0.2 0.7 0.0 5.6 59.0 74.4 0.0 0.4 0.4 53.7 7.2 0.7 0.0 0.0 0.3 7.3 0.0 0.6 CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149858-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.6;choroid plexus: 28.1;fallopian tube: 42.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 110.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.3;REH: 2.2;T-47d: 2.5;U-698: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" 0.2 0.4 3.2 0.4 2.8 2.1 0.3 1.1 1.0 3.8 28.1 0.3 0.3 0.5 0.3 0.5 42.2 0.2 0.2 5.5 5.8 1.7 0.5 7.1 0.7 17.9 21.6 0.4 0.4 0.1 1.2 0.0 11.3 0.6 0.0 0.2 2.3 0.7 0.3 4.7 0.5 0.0 15.0 0.6 4.0 0.5 4.6 0.0 0.8 0.0 1.2 0.2 0.2 3.4 0.2 0.0 0.2 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 2.0 4.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.2 1.7 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.7 0.2 0.7 0.3 0.8 0.1 2.2 0.0 0.3 0.5 0.5 0.4 0.1 0.0 0.6 0.0 0.2 2.5 0.0 0.1 0.1 0.7 0.2 0.1 0.4 0.1 9.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 1.1 1.0 5.5 5.8 17.9 21.6 11.3 15.0 4.6 3.4 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 6.2 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.4 110.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.6 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 23.3 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.2 CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;choroid plexus: 5.8;fallopian tube: 3.9;retina: 1.5;testis: 5.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Early spermatids: 11.6;Endometrial ciliated cells: 13.6;Late spermatids: 11.2;Rod photoreceptor cells: 5.5;Spermatocytes: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (7.54e-3)" "unprognostic (6.46e-3)" "unprognostic (1.12e-1)" "unprognostic (2.31e-3)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.89e-1)" "unprognostic (8.14e-2)" "unprognostic (7.93e-5)" "unprognostic (1.15e-1)" "unprognostic (5.97e-3)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (6.94e-2)" "unprognostic (3.49e-1)" 0.0 0.8 0.5 0.0 0.5 0.0 0.0 0.8 0.3 0.2 5.8 0.0 0.0 0.2 0.1 0.0 3.9 0.0 0.0 0.9 0.8 0.2 0.1 0.6 0.0 3.2 4.8 0.0 0.3 0.0 0.8 0.0 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 5.3 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 0.3 0.9 0.8 3.2 4.8 1.8 2.0 1.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.2 0.0 1.8 3.7 4.2 0.0 0.0 0.0 0.0 0.2 11.6 13.6 0.2 0.1 0.0 0.0 1.2 0.6 0.1 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 11.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 1.5 2.9 5.5 0.0 0.0 0.0 14.0 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.6;intestine: 42.7;pancreas: 210.7" "Group enriched" "Detected in many" 4 "Ductal cells: 485.4;Ionocytes: 252.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "CACO-2: 29.5;MOLT-4: 98.9;U-266/70: 49.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" 0.4 0.0 0.5 4.7 2.0 0.0 0.4 0.7 1.3 8.5 0.0 42.7 36.2 1.1 1.1 0.8 2.2 54.6 0.1 0.3 0.7 2.1 1.6 8.2 0.0 1.1 0.7 0.0 210.7 0.2 0.1 0.6 0.7 2.2 40.7 0.0 21.5 0.5 0.0 1.9 19.9 2.0 1.7 0.0 3.1 1.7 1.0 0.1 0.1 0.0 0.3 0.7 0.0 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 98.9 0.1 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 49.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.7 1.3 0.3 0.7 1.1 0.7 0.7 1.7 1.0 2.9 0.0 6.4 65.6 0.0 0.5 0.0 2.0 2.6 0.0 0.5 0.5 0.0 2.4 55.8 17.8 0.0 0.0 0.0 0.0 45.8 0.0 485.4 3.2 9.6 1.2 0.4 7.2 0.0 2.2 4.5 0.0 0.3 4.1 19.8 1.3 0.1 0.0 0.4 0.0 0.0 1.1 13.9 252.3 0.0 0.0 2.6 0.3 0.1 0.0 1.0 6.7 0.5 0.0 0.5 23.8 14.8 86.4 0.0 0.0 4.0 8.6 0.0 5.6 0.0 0.0 0.0 1.6 2.2 0.5 0.0 0.0 0.0 0.3 0.1 87.3 5.8 CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" 105.8 112.3 93.3 75.8 95.3 213.7 102.2 93.9 112.3 112.9 82.5 155.1 103.0 107.8 58.6 159.0 84.4 80.6 147.1 98.4 98.9 122.9 67.7 101.5 70.7 97.7 94.5 94.9 82.1 74.8 74.6 74.7 95.6 90.4 98.7 53.3 118.1 82.4 231.3 120.9 119.9 76.3 93.7 83.0 117.3 60.2 97.5 82.8 88.4 132.6 71.2 132.0 106.9 99.4 206.4 131.3 72.3 69.3 118.8 95.2 114.5 120.4 159.1 126.1 117.5 279.1 171.2 98.1 183.3 122.3 192.0 160.8 83.2 182.3 99.2 51.0 89.3 174.1 90.4 189.3 137.5 86.1 88.1 137.2 99.4 116.3 106.6 125.2 141.9 113.1 84.2 139.0 97.8 130.2 189.8 246.5 63.4 226.3 179.8 97.7 147.2 120.7 142.7 234.0 56.4 68.6 225.0 192.2 165.8 85.1 149.0 123.9 129.9 216.8 85.0 108.7 117.9 132.4 101.3 117.0 176.5 91.6 65.8 0.0 1.8 0.8 0.7 1.7 0.9 1.6 1.1 0.8 1.0 1.1 0.8 0.7 2.3 0.5 1.4 4.0 1.4 0.5 93.3 95.3 93.9 112.3 98.4 98.9 97.7 94.5 95.6 93.7 97.5 99.4 66.0 60.9 54.6 17.9 71.5 298.0 224.4 133.8 113.3 22.5 149.1 64.3 95.9 112.9 148.1 110.3 18.8 197.7 77.9 565.8 144.8 360.9 17.8 81.8 76.1 126.0 127.4 81.6 18.7 497.0 151.2 130.1 112.7 130.6 28.5 22.3 71.7 69.8 215.3 18.5 13.8 212.7 154.6 119.3 383.6 18.8 93.8 140.2 220.5 15.0 289.8 73.6 46.4 10.6 17.4 540.2 536.6 120.7 139.0 426.2 482.1 180.0 101.6 20.9 92.1 79.7 120.5 24.5 29.2 291.0 341.3 440.3 62.9 35.7 227.4 413.2 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CHRD ENSG00000090539 Chordin Q9H2X0 3 184380073-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 130.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 31.2;Excitatory neurons: 28.2;Fibroblasts: 16.4;Hepatocytes: 36.4;Inhibitory neurons: 37.5;Skeletal myocytes: 19.1;Smooth muscle cells: 16.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.8;Hep G2: 11.8;MCF7: 2.5;SuSa: 4.0;U-2 OS: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035827 Approved "Secreted in other tissues" NA NA 350000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 36: Stromal cells - Cell proliferation" "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" 11.1 12.2 13.9 2.1 13.9 0.0 9.9 19.0 21.2 40.0 9.1 7.6 1.6 32.9 3.2 3.3 15.0 2.5 11.2 15.1 9.4 18.8 130.0 7.2 1.5 10.1 9.9 16.3 17.1 1.1 6.0 2.4 10.2 9.7 0.8 0.0 3.8 5.2 4.4 5.4 6.0 4.6 10.3 9.7 7.8 1.1 9.7 0.2 7.7 2.7 0.3 7.2 15.4 13.6 0.0 0.0 0.3 1.1 0.1 0.1 1.4 0.3 0.0 0.2 0.1 2.8 0.0 0.0 1.1 0.3 1.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 11.8 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 4.0 1.4 0.0 0.0 0.0 3.8 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 13.9 19.0 21.2 15.1 9.4 10.1 9.9 10.2 10.3 9.7 13.6 2.6 0.0 0.0 11.8 0.4 2.7 0.0 0.0 0.6 2.9 2.1 1.8 3.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.1 3.6 31.2 2.6 0.0 0.0 28.2 3.1 0.0 16.4 1.1 4.5 0.0 0.9 3.3 36.4 0.7 0.0 37.5 0.2 0.0 3.2 3.1 0.0 3.7 0.4 1.8 4.7 0.0 0.0 0.0 7.1 2.5 1.1 0.0 2.2 0.0 0.1 0.0 4.0 0.0 0.5 6.6 19.1 16.4 0.3 0.3 0.3 1.1 0.1 0.7 0.1 0.0 0.3 CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 27.0;prostate: 29.6;salivary gland: 28.8" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Breast myoepithelial cells: 3.6;Excitatory neurons: 8.7;Inhibitory neurons: 7.8;Intestinal goblet cells: 3.2;Melanocytes: 3.6;Oligodendrocyte precursor cells: 3.0;Prostatic glandular cells: 4.4" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 178 "amygdala: 12.4;basal ganglia: 18.7;cerebral cortex: 27.0;hippocampal formation: 22.6;white matter: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "MCF7: 3.7;OE19: 12.3" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" 0.0 3.3 12.4 0.3 18.7 0.0 2.7 0.0 27.0 0.0 0.0 0.8 0.4 0.1 0.0 0.3 0.2 0.1 0.1 22.6 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.6 0.3 0.2 0.2 0.0 29.6 0.7 0.1 28.8 0.0 0.0 2.8 0.7 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 12.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.4 0.1 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 18.7 0.0 27.0 22.6 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 2.9 0.0 0.1 0.2 0.0 0.0 0.0 1.8 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.8 3.2 0.0 0.0 0.3 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 3.0 1.0 0.0 0.1 0.0 0.0 4.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.1 CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.9;Fibroblasts: 138.1;Leydig cells: 231.5;Peritubular cells: 57.6;Theca cells: 83.5" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.2;ASC TERT1: 2.5;EFO-21: 1.1;HSkMC: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" NA NA 13000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" 49.8 0.8 0.2 9.5 0.2 0.1 21.9 0.3 0.3 44.9 0.1 20.3 2.3 13.8 3.6 11.0 15.8 36.8 27.4 0.2 0.2 1.0 1.6 2.9 1.6 0.2 0.2 7.5 3.0 0.3 0.7 2.5 0.2 3.1 6.9 0.5 9.4 4.8 15.5 14.0 22.6 51.0 0.2 0.6 8.3 12.1 0.2 1.8 2.4 32.9 0.8 26.9 28.1 0.2 0.0 0.0 0.0 0.0 4.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 8.1 0.0 0.0 0.0 0.0 5.2 0.1 0.2 0.0 0.9 0.4 0.5 2.1 0.0 0.4 1.8 0.0 0.0 0.2 0.1 0.0 0.1 1.7 1.2 42.9 1.5 0.0 0.0 0.3 0.0 0.0 138.1 4.1 1.7 0.0 0.1 2.2 0.1 0.1 0.0 0.6 0.1 2.0 0.0 11.9 7.1 231.5 1.7 1.8 1.9 0.0 0.2 0.0 1.0 0.3 0.0 0.0 57.6 0.3 0.1 0.0 0.0 0.0 0.1 0.0 14.7 6.6 0.6 0.3 0.1 6.1 0.0 1.6 83.5 0.2 0.0 CITED1 MSG1 ENSG00000125931 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1" Q99966 X 72301638-72307187 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "epididymis: 1473.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 87.4;Breast myoepithelial cells: 47.6;Granulosa cells: 31.0;Late spermatids: 58.4;Paneth cells: 33.8" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 134.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 244.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049051 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA049051: AB_2680612" "unprognostic (7.04e-2)" "unprognostic (3.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-3)" "unprognostic (8.81e-2)" "unprognostic (5.67e-4)" "unprognostic (3.40e-1)" "unprognostic (9.55e-2)" "unprognostic (4.60e-3)" "unprognostic (4.38e-2)" "unprognostic (6.33e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "prognostic favorable (6.10e-4)" "prognostic favorable (3.95e-4)" "unprognostic (2.99e-2)" 2.3 5.1 13.0 0.3 6.9 0.2 23.1 5.1 12.2 5.9 3.4 1.0 0.7 3.6 1473.6 0.3 1.5 0.0 0.7 6.7 56.2 5.1 0.4 0.6 0.3 8.5 8.8 1.5 1.5 0.0 209.9 0.0 24.5 11.2 0.2 4.5 0.8 3.0 0.4 0.6 1.0 8.1 4.3 0.4 1.0 199.9 30.6 0.2 8.0 0.4 0.1 0.5 1.0 6.2 0.4 0.3 2.2 57.1 2.5 0.0 2.1 0.0 0.5 0.4 0.3 0.1 0.6 0.0 0.2 0.0 0.6 0.0 20.5 1.4 0.1 6.1 8.0 0.9 0.4 0.0 0.0 0.2 10.4 1.1 0.8 0.5 1.0 0.2 0.2 0.2 2.5 0.0 0.4 0.8 0.2 4.4 3.3 0.0 3.6 0.1 3.6 3.2 0.1 0.4 25.8 12.5 0.4 5.1 244.4 0.2 1.4 1.0 0.0 0.2 1.9 0.4 0.8 0.2 0.5 0.2 0.5 0.4 5.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 6.9 5.1 12.2 6.7 56.2 8.5 8.8 24.5 4.3 30.6 6.2 2.2 0.0 0.0 0.0 0.0 0.1 1.0 0.4 0.0 5.6 87.4 47.6 0.4 1.5 0.1 3.7 6.2 0.1 0.3 0.3 0.0 0.1 20.4 0.5 0.8 1.0 1.2 0.0 0.7 0.8 0.1 0.7 0.0 0.3 0.0 31.0 0.4 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.7 58.4 7.5 0.8 3.6 1.9 0.1 1.7 0.0 0.0 0.1 0.4 33.8 3.0 0.0 19.3 0.7 0.3 0.0 3.8 13.1 1.2 3.2 12.6 6.8 0.0 0.0 0.0 0.1 0.5 0.5 1.0 CLEC1A "CLEC1, MGC34328" ENSG00000150048 "C-type lectin domain family 1 member A" Q8NC01 12 10069554-10111627 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 50.2;placenta: 49.0" "Cell type enhanced" "Detected in some" "Adipocytes: 51.4;Cytotrophoblasts: 51.5;Endothelial cells: 38.1;Extravillous trophoblasts: 61.7;Syncytiotrophoblasts: 52.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 21.3;HUVEC TERT2: 18.3;SuSa: 5.6;U-266/70: 4.9;U-266/84: 11.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (7.63e-2)" "unprognostic (2.51e-2)" "unprognostic (5.96e-2)" "unprognostic (2.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-2)" "unprognostic (1.37e-1)" "unprognostic (1.03e-1)" "unprognostic (7.15e-2)" "unprognostic (2.73e-2)" "unprognostic (3.26e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.94e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" 16.2 3.2 4.4 4.1 4.2 0.4 14.8 6.6 5.6 11.4 4.1 4.3 1.5 6.8 2.7 3.8 9.2 5.7 9.0 3.9 3.8 5.8 2.9 29.8 5.9 4.8 4.5 5.4 2.3 1.6 3.7 49.0 4.7 6.3 2.0 0.6 2.9 2.4 3.9 4.1 4.4 8.7 4.3 8.0 3.7 2.1 5.1 50.2 7.6 4.4 3.5 6.1 8.6 4.1 0.0 0.0 0.3 0.3 0.2 0.2 21.3 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 1.2 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.9 0.0 0.0 0.0 0.4 3.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.4 0.0 0.3 0.3 0.0 5.6 0.0 0.0 1.4 0.0 0.2 0.2 0.0 4.9 11.5 0.0 0.2 0.1 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 4.4 4.2 6.6 5.6 3.9 3.8 4.8 4.5 4.7 4.3 5.1 4.1 51.4 0.0 0.5 0.0 0.5 2.2 0.1 0.0 1.2 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 51.5 0.2 0.0 0.0 0.0 0.4 0.0 0.1 38.1 0.0 0.0 0.0 0.0 61.7 1.2 0.0 0.0 0.0 0.0 16.8 0.2 5.0 0.0 0.0 0.0 0.0 4.7 14.1 0.6 7.5 4.0 3.6 11.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.9 4.0 2.9 0.3 1.6 52.1 0.6 0.3 0.0 0.5 CLEC4G "LSECtin, UNQ431" ENSG00000182566 "C-type lectin domain family 4 member G" Q6UXB4 19 7728958-7733906 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 14.9;liver: 53.3;lymphoid tissue: 15.1" "Cell type enriched" "Detected in some" 15 "Hepatic stellate cells: 730.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 18.8;myeloid DC: 15.1" "Group enriched" "Detected in many" 4 "dendritic cells: 15.1;monocytes: 18.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003789, HPA014044" Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB003789: , HPA014044: AB_1846916" "unprognostic (7.20e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.64e-1)" "unprognostic (4.47e-2)" "unprognostic (1.35e-1)" "unprognostic (7.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (3.29e-2)" "unprognostic (7.45e-2)" "unprognostic (3.04e-1)" "unprognostic (2.13e-8)" "unprognostic (5.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (6.65e-2)" 14.9 0.5 1.9 2.4 1.9 1.2 2.6 4.0 2.9 0.1 2.0 1.4 0.4 0.1 0.3 0.4 4.8 1.6 1.2 2.5 1.9 0.5 53.3 1.0 15.1 2.3 2.1 0.5 0.3 0.0 0.1 1.0 2.1 0.3 0.9 0.0 1.1 0.3 0.4 1.1 2.0 1.0 2.1 3.4 0.9 0.4 4.3 0.2 0.5 0.0 0.3 7.7 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.8 0.0 0.0 4.2 0.0 0.3 0.0 0.0 15.1 4.2 0.1 0.0 0.4 0.5 0.5 0.7 0.0 4.5 1.9 1.9 4.0 2.9 2.5 1.9 2.3 2.1 2.1 2.1 4.3 2.1 0.1 0.0 0.0 0.3 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 18.7 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 730.3 7.1 0.8 0.0 1.1 0.0 0.0 46.7 2.9 0.0 0.3 2.6 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.7 0.0 0.3 0.3 1.1 0.8 0.0 0.1 CLGN ENSG00000153132 Calmegin O14967 4 140388453-140427661 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 59.5;testis: 113.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313.3;Early spermatids: 162.4;Endometrial ciliated cells: 93.4;Muller glia cells: 176.4;Spermatocytes: 465.5" "Cancer enhanced" "Detected in many" "prostate cancer: 19.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 53.0;MOLT-4: 47.8;U-251 MG: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020709, HPA048761, HPA058627" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum" "CAB020709: , HPA048761: AB_2680514, HPA058627: AB_2683782" "unprognostic (6.74e-2)" "unprognostic (8.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" "unprognostic (3.73e-3)" "unprognostic (6.14e-2)" "unprognostic (4.80e-2)" "unprognostic (3.11e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.45e-3)" "unprognostic (3.00e-3)" "unprognostic (1.29e-1)" "unprognostic (2.59e-1)" "unprognostic (1.01e-1)" 0.4 6.6 0.9 1.0 0.7 2.4 2.7 3.8 1.6 0.9 2.0 2.6 0.5 1.6 0.6 1.2 13.7 0.4 59.5 0.9 2.6 0.4 3.2 0.5 0.7 2.7 1.9 0.3 2.2 0.6 11.2 0.2 2.6 22.5 1.3 17.2 1.0 0.7 0.4 0.2 1.3 1.5 1.2 0.2 2.0 113.6 2.3 2.4 2.7 1.6 1.2 0.6 0.1 0.9 0.2 10.2 10.3 6.9 4.0 21.1 2.4 0.1 9.4 10.0 18.6 0.3 0.9 0.0 27.8 0.9 8.4 0.2 7.5 0.1 16.2 0.4 9.0 3.0 9.8 7.4 41.4 38.9 0.6 2.2 39.2 1.0 0.9 53.0 0.2 9.6 2.0 0.0 0.0 0.5 47.8 0.5 12.0 0.2 28.1 31.5 0.0 0.4 0.0 0.3 16.8 29.8 6.5 4.1 1.8 3.8 1.9 5.6 0.0 27.4 4.7 9.7 73.6 14.4 31.7 19.9 43.4 1.6 2.9 0.9 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 3.8 1.6 0.9 2.6 2.7 1.9 2.6 1.2 2.3 0.9 0.8 0.0 2.2 0.3 0.1 0.0 0.9 8.5 1.2 9.2 3.3 1.8 313.3 0.0 6.4 0.0 4.2 0.5 0.0 0.5 0.0 1.2 162.4 93.4 1.3 11.9 5.3 8.6 7.2 4.2 0.1 10.2 0.0 11.3 0.0 10.1 0.7 3.7 0.1 25.2 6.7 0.4 30.5 0.0 0.0 60.2 5.0 0.7 1.8 0.0 0.1 176.4 0.0 6.6 0.6 0.9 3.9 4.5 0.1 33.8 0.2 0.1 24.6 16.3 0.0 0.6 2.0 465.5 23.9 2.8 0.1 0.3 0.7 0.2 0.8 1.3 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLN3 "BTN1, BTS, JNCL" ENSG00000188603 "CLN3 lysosomal/endosomal transmembrane protein, battenin" Q13286 16 28474111-28495575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.9;Extravillous trophoblasts: 106.9;Syncytiotrophoblasts: 451.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 178.0;SK-BR-3: 186.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063280 Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA063280: AB_2684975" "unprognostic (2.38e-3)" "unprognostic (2.41e-2)" "unprognostic (7.06e-2)" "unprognostic (8.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-2)" "unprognostic (6.38e-3)" "unprognostic (8.16e-2)" "unprognostic (6.27e-2)" "unprognostic (5.26e-1)" "unprognostic (9.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-2)" 18.1 30.5 13.1 19.6 14.2 13.4 21.4 14.2 16.0 16.9 16.5 38.3 21.9 15.9 9.9 22.2 16.0 15.2 11.7 13.2 13.6 21.2 31.9 23.6 13.8 14.6 13.6 16.8 27.7 30.0 8.2 36.9 15.1 17.3 29.2 3.1 34.5 21.0 14.5 24.1 25.7 13.3 13.5 20.4 26.1 7.9 15.6 14.0 24.7 13.8 12.1 19.3 15.6 17.1 23.1 39.2 15.4 38.4 41.1 19.9 178.0 14.8 40.7 28.3 34.9 19.7 52.9 16.0 45.8 24.8 52.0 23.5 25.8 24.7 12.9 38.0 38.5 15.6 24.1 60.6 60.5 23.3 64.7 28.0 66.8 21.9 14.7 26.3 32.9 24.9 30.9 55.0 28.8 61.9 20.7 45.1 21.8 35.3 26.0 37.2 13.4 54.5 30.2 53.0 20.8 19.6 5.7 186.5 18.3 14.0 62.2 32.4 20.2 19.2 10.1 24.9 22.5 58.3 64.2 15.9 28.4 47.3 11.9 63.4 59.8 98.4 57.6 47.6 42.7 24.3 43.6 53.6 63.8 29.3 38.3 40.6 23.8 41.2 38.7 68.1 53.5 46.6 13.1 14.2 14.2 16.0 13.2 13.6 14.6 13.6 15.1 13.5 15.6 17.1 1.2 22.4 15.9 11.1 10.8 0.1 17.2 0.0 23.9 10.9 1.7 0.6 0.0 38.6 6.2 1.8 12.5 315.9 25.8 46.4 0.0 2.2 1.1 1.8 1.3 11.2 17.0 17.5 7.5 0.5 106.9 9.3 20.9 2.6 2.5 7.6 21.0 39.0 70.1 13.5 8.1 39.3 0.0 36.7 0.4 2.5 19.0 17.7 0.0 2.8 17.5 25.0 40.2 7.1 11.4 1.5 43.7 12.4 13.1 10.6 53.1 0.8 1.5 12.1 13.1 9.9 3.5 3.2 8.4 17.1 0.1 451.4 15.9 3.6 50.2 13.3 CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enriched" "Detected in many" 5 "Ionocytes: 73.2" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HDLM-2: 4.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" 0.3 0.2 0.5 0.9 0.4 0.4 0.6 1.5 0.7 0.2 0.5 0.3 0.6 0.4 1.2 0.4 0.2 0.5 0.2 0.5 0.5 6.2 0.9 0.6 3.0 0.4 0.2 0.4 0.1 0.1 1.3 1.0 0.5 0.4 0.4 0.3 0.5 0.3 0.2 0.8 0.9 0.1 0.1 1.5 1.1 0.8 0.5 1.4 0.3 0.0 2.0 0.3 0.0 0.9 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.2 0.1 0.5 0.1 0.2 0.2 0.1 0.1 1.4 0.4 0.1 2.6 1.1 0.1 0.1 0.4 2.0 0.0 0.6 1.8 0.2 0.5 0.4 1.5 0.7 0.5 0.5 0.4 0.2 0.5 0.1 0.5 0.9 0.1 3.2 3.0 1.0 12.9 0.8 0.8 0.0 0.0 1.3 0.3 0.3 0.7 0.0 0.9 0.0 2.1 0.3 4.6 0.1 13.7 0.0 5.3 0.7 0.2 0.4 0.0 5.3 1.7 0.0 2.2 0.5 0.5 0.9 11.4 0.2 0.7 0.3 0.3 0.0 1.6 0.2 73.2 1.9 5.5 5.4 0.3 3.5 1.8 1.9 0.5 0.4 0.0 1.0 0.7 0.1 0.0 2.2 1.1 0.7 0.0 0.2 0.2 1.0 0.0 1.1 0.5 1.9 0.8 0.0 0.4 0.1 6.0 1.3 0.0 0.7 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.3" "Cell type enhanced" "Detected in some" "dendritic cells: 17.3;Hofbauer cells: 32.4;Kupffer cells: 69.6;Macrophages: 27.1;Microglial cells: 39.4;NK-cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.5;plasmacytoid DC: 18.1" "Group enriched" "Detected in many" 22 "dendritic cells: 18.1;monocytes: 14.5;T-cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 11.9;ASC TERT1: 45.3;BJ hTERT+: 34.9;hTERT-RPE1: 13.6;LHCN-M2: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" 10.4 5.9 3.3 11.7 3.0 0.9 4.9 2.5 3.2 4.7 4.2 7.5 4.5 8.3 1.6 3.1 4.4 5.5 6.4 2.6 4.9 3.3 6.9 12.8 17.6 5.9 4.7 1.9 3.2 1.7 3.4 22.2 5.3 3.8 8.9 0.3 4.7 4.5 2.4 4.2 5.1 14.7 4.0 34.3 2.8 2.6 5.9 4.2 8.7 5.1 8.1 8.1 2.5 7.5 0.0 0.0 0.1 0.0 11.9 45.3 0.2 0.0 34.9 0.1 0.0 0.0 0.0 0.2 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.2 13.6 0.7 0.0 0.0 0.0 10.6 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.9 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 4.1 0.0 7.0 14.5 0.0 0.0 1.1 5.1 1.1 0.0 0.4 3.5 0.3 0.6 2.8 18.1 0.3 5.1 3.3 3.0 2.5 3.2 2.6 4.9 5.9 4.7 5.3 4.0 5.9 7.5 1.9 0.0 0.0 0.0 0.9 0.9 0.0 0.0 0.0 0.0 0.1 0.3 2.2 1.5 0.6 0.0 0.0 0.4 17.3 0.0 0.0 0.0 0.1 0.0 0.7 5.8 0.0 2.7 0.5 0.0 0.5 7.8 0.0 0.0 0.0 0.0 11.4 0.6 32.4 0.0 0.4 0.0 0.0 69.6 2.5 0.3 0.3 27.1 3.6 39.4 7.6 0.0 30.9 1.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.7 0.1 6.6 4.1 5.1 0.0 0.0 0.1 0.6 0.5 2.2 0.5 0.0 0.0 CMTM3 "BNAS2, CKLFSF3, FLJ31762" ENSG00000140931 "CKLF like MARVEL transmembrane domain containing 3" Q96MX0 16 66603874-66613892 "Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 222.1;Granulosa cells: 140.8;Hofbauer cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013870, HPA072695" Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA013870: AB_1847003, HPA072695: AB_2732210" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (7.63e-2)" "unprognostic (1.49e-1)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (1.80e-3)" "unprognostic (6.65e-3)" "unprognostic (7.75e-2)" "unprognostic (1.60e-2)" "unprognostic (1.22e-2)" "unprognostic (7.38e-2)" "prognostic unfavorable (4.42e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (7.56e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" 49.3 16.6 15.5 25.0 14.3 20.0 32.8 15.6 28.1 40.2 9.5 16.8 7.1 30.4 16.6 10.4 25.5 32.7 26.2 15.6 18.0 19.7 10.7 35.4 32.3 24.9 15.8 38.9 7.9 29.4 10.1 44.4 19.3 23.4 12.1 3.0 17.4 16.7 6.4 22.2 18.8 27.7 17.0 36.1 11.9 59.7 19.1 35.5 16.1 13.0 20.9 34.3 26.7 20.4 6.7 33.8 93.4 66.2 68.4 42.6 59.2 17.5 78.6 34.4 34.0 18.6 21.0 0.2 47.7 49.0 59.7 7.8 63.7 57.4 27.3 34.6 23.2 21.5 4.4 53.5 92.2 65.8 77.4 85.5 4.5 36.6 7.7 141.3 78.9 59.5 34.6 0.7 42.8 7.8 53.1 108.9 45.0 0.5 31.8 164.7 65.6 3.3 16.4 0.8 9.9 33.9 8.5 0.3 58.5 59.9 0.7 59.3 54.0 48.7 58.8 12.0 21.1 4.4 0.7 21.8 30.5 50.0 53.7 7.9 14.2 9.9 9.2 13.9 12.9 2.6 10.3 10.5 12.3 0.9 8.0 9.8 8.0 8.6 8.9 24.9 15.7 5.8 15.5 14.3 15.6 28.1 15.6 18.0 24.9 15.8 19.3 17.0 19.1 20.4 38.0 0.0 7.1 0.3 12.9 14.7 33.5 10.0 6.8 0.5 12.3 25.7 2.0 4.3 6.4 5.5 0.0 10.7 101.2 0.4 0.0 28.1 2.8 4.9 56.0 50.4 12.5 12.8 0.6 6.4 222.1 62.6 2.6 6.2 91.3 140.8 44.3 1.3 119.8 0.0 0.3 0.7 8.2 74.7 77.9 9.4 39.4 78.0 28.4 10.3 61.5 10.0 82.4 8.0 0.2 41.0 0.1 24.5 5.7 40.8 0.1 4.4 3.1 0.8 6.6 26.3 36.1 4.9 8.1 1.1 8.7 9.4 68.9 10.5 0.2 21.6 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 334.7;Proximal enterocytes: 629.1;Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 458.7;RPMI-8226: 616.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 54.8 40.7 125.3 75.0 147.0 25.1 60.4 139.4 156.9 136.8 113.0 83.6 190.1 44.2 122.8 78.4 140.8 94.4 63.7 123.7 133.2 327.3 261.1 82.3 86.3 143.1 137.4 34.4 100.7 58.5 48.0 75.4 144.7 122.5 79.5 42.1 57.4 101.7 26.6 47.0 255.0 37.9 140.4 137.0 103.5 20.9 143.9 52.5 159.1 22.4 82.2 94.5 47.4 157.6 64.6 85.0 60.5 57.4 72.2 42.5 252.3 66.0 61.7 88.3 87.4 49.6 67.1 80.3 81.4 72.1 69.0 95.0 92.7 124.9 62.7 121.3 36.7 80.2 42.1 79.6 104.6 158.7 119.3 64.5 93.9 76.4 136.6 50.1 78.3 94.6 86.3 458.7 59.1 71.6 84.9 75.6 91.0 42.4 50.3 91.3 69.4 616.6 346.1 264.1 65.3 34.2 51.6 360.2 91.6 143.0 151.5 64.0 82.5 93.9 79.5 21.2 45.2 85.5 380.6 108.1 63.6 113.8 80.2 37.1 115.4 49.0 77.6 166.3 84.4 102.4 61.6 72.2 185.1 110.5 65.5 72.4 15.9 124.6 174.1 161.3 94.5 135.7 125.3 147.0 139.4 156.9 123.7 133.2 143.1 137.4 144.7 140.4 143.9 157.6 39.2 73.7 62.7 16.6 55.7 9.2 40.3 48.6 12.5 33.6 76.5 36.4 26.9 77.2 56.8 119.5 16.7 157.9 47.8 99.0 187.9 168.1 3.3 187.7 49.7 49.6 65.3 23.3 8.8 154.7 130.9 23.5 63.7 334.7 12.0 34.0 40.0 119.8 216.3 43.7 10.8 82.9 75.3 122.9 24.9 4.1 18.6 79.0 17.8 13.1 90.8 86.6 55.6 15.6 51.7 108.9 103.5 16.6 44.4 65.2 629.1 487.6 73.3 31.6 13.1 15.2 22.3 8.3 7.2 27.1 9.7 109.0 38.2 32.8 99.8 53.8 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 70.5;Late spermatids: 124.8;Respiratory ciliated cells: 47.0;Spermatocytes: 150.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.9;ASC diff: 1.6;SiHa: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" 0.3 0.2 0.9 0.0 0.9 0.1 1.8 1.2 1.9 0.1 0.1 0.8 0.1 0.1 1.4 0.0 0.7 0.0 0.1 0.9 1.0 1.5 0.0 0.5 0.0 1.0 0.9 0.4 1.0 0.3 0.0 0.1 0.9 1.3 1.9 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.1 3.3 42.4 0.8 0.0 0.3 0.6 0.0 0.2 0.0 1.9 2.9 0.3 0.2 0.5 1.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.3 0.0 0.8 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.2 1.9 0.9 1.0 1.0 0.9 0.9 0.8 0.8 1.9 1.2 3.2 4.6 2.3 1.0 0.4 0.5 0.4 0.0 1.7 5.5 2.2 1.1 1.5 2.1 0.0 0.0 0.3 1.2 1.4 5.9 0.2 70.5 5.4 1.7 0.8 0.0 2.7 1.9 0.4 0.4 1.9 4.1 1.6 6.3 0.2 0.4 1.1 0.3 6.7 1.6 5.3 4.1 1.0 0.7 124.8 2.5 1.1 0.0 0.0 0.2 1.0 0.0 2.0 1.1 0.4 0.4 1.2 0.7 5.6 0.9 0.5 47.0 0.7 6.6 1.0 1.7 150.2 17.1 0.0 0.6 0.3 0.9 0.5 2.7 2.3 COASY "DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" NA NA 20000 "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favorable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" 27.4 60.0 24.0 23.1 24.0 29.5 32.8 24.7 28.1 27.6 26.7 35.6 43.3 25.2 17.2 54.4 29.8 16.9 29.4 25.4 23.9 45.6 70.9 30.3 25.0 27.8 24.7 26.0 59.0 39.0 30.3 25.5 28.1 32.4 24.3 13.3 58.5 28.7 38.6 46.6 36.9 17.2 23.8 35.9 47.2 32.4 25.7 27.6 39.0 25.3 25.2 26.8 31.1 24.6 94.2 149.1 27.2 55.2 55.5 34.8 89.2 38.3 52.9 65.8 46.5 85.7 89.2 52.7 65.6 50.4 69.5 146.9 66.1 81.4 43.7 47.6 122.2 52.5 91.2 140.9 70.2 56.4 73.1 51.5 97.8 62.4 66.6 52.4 63.2 70.5 98.7 70.8 46.6 59.2 71.5 87.2 36.7 125.8 75.1 39.1 93.5 88.1 89.9 66.7 63.3 50.1 34.9 37.3 75.4 52.2 158.0 70.4 41.6 68.3 62.3 52.4 40.1 84.6 127.4 31.0 80.9 55.3 47.5 23.3 29.8 26.8 19.7 31.8 20.5 15.8 15.8 19.1 33.6 15.7 15.7 16.3 19.5 21.0 22.5 23.6 18.1 24.0 24.0 24.0 24.7 28.1 25.4 23.9 27.8 24.7 28.1 23.8 25.7 24.6 15.4 6.4 23.8 9.8 24.1 15.0 21.7 49.5 25.6 17.8 38.2 22.9 22.9 40.0 33.3 71.7 0.0 89.4 21.2 53.7 33.2 44.8 4.4 31.5 20.6 20.6 17.4 30.3 5.6 52.5 51.6 18.7 40.2 28.0 10.2 101.2 23.9 94.2 40.3 33.7 5.7 36.7 42.7 23.6 16.1 7.7 14.9 19.9 14.2 4.7 36.2 29.4 20.6 3.5 5.9 38.9 32.4 16.6 25.3 31.2 66.3 94.8 36.5 18.0 26.3 15.2 18.6 46.7 31.1 33.4 17.8 77.2 16.9 36.6 45.1 30.7 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 900.3" "Cell type enhanced" "Detected in many" "Adipocytes: 401.4;Endometrial stromal cells: 312.2;Endothelial cells: 385.9;Extravillous trophoblasts: 672.4;Sertoli cells: 506.2;Smooth muscle cells: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "ASC diff: 501.6;EFO-21: 915.3;TIME: 331.3" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" NA NA 75000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" 348.4 33.6 10.8 135.9 5.2 0.4 130.4 3.7 9.0 65.7 8.9 108.5 24.8 105.3 14.8 40.8 64.1 116.8 81.9 12.6 5.2 53.4 22.1 137.0 27.7 9.1 7.0 27.0 36.0 36.3 12.8 900.3 7.5 53.6 30.4 1.8 19.0 85.6 40.1 25.2 43.4 312.7 6.8 76.3 50.1 10.7 13.7 10.7 54.7 47.0 11.1 120.8 38.2 6.9 40.0 15.2 195.9 0.3 501.6 148.9 274.9 246.2 59.5 134.0 65.3 4.2 0.8 0.1 915.3 46.2 59.7 26.8 0.0 55.8 30.3 1.3 29.5 0.2 28.2 0.0 142.8 0.0 0.4 49.7 8.9 132.8 59.4 212.8 207.7 0.1 0.3 0.2 31.1 0.1 0.1 0.8 28.1 0.2 3.6 0.4 58.6 0.1 278.8 0.0 1.4 29.8 0.1 0.4 61.0 192.4 0.1 13.9 331.3 39.9 121.4 1.0 97.4 0.3 1.8 3.9 0.4 0.7 297.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 10.8 5.2 3.7 9.0 12.6 5.2 9.1 7.0 7.5 6.8 13.7 6.9 401.4 41.7 8.9 5.2 1.9 14.0 9.7 8.5 2.8 1.0 3.5 16.5 41.1 10.0 0.9 23.9 0.0 49.7 0.5 0.1 1.9 22.6 0.7 19.8 312.2 385.9 0.0 0.0 10.5 0.2 672.4 211.8 1.5 48.7 1.3 215.8 134.6 1.3 27.7 0.0 18.9 0.5 0.0 4.4 19.2 2.8 38.5 4.2 30.2 36.5 0.6 2.5 0.0 1.0 0.9 0.6 0.1 109.4 0.5 6.2 0.5 26.7 2.8 0.4 506.2 142.8 415.1 1.2 5.0 0.8 15.2 45.0 4.2 45.9 0.6 2.2 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981769-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 796.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 578.3;Fibroblasts: 816.1;Leydig cells: 353.0;Peritubular cells: 251.3;Smooth muscle cells: 324.4;Theca cells: 246.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1157.2;ASC TERT1: 2331.5;BJ: 927.1;HHSteC: 1025.3;HSkMC: 1711.4;U-138 MG: 1297.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 46.8" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" NA NA 250000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" 285.9 50.1 15.7 153.3 9.0 0.7 173.9 33.9 20.4 499.3 32.1 796.8 73.3 556.3 24.6 91.1 411.5 194.4 155.6 10.3 14.9 66.1 48.3 140.3 37.5 23.1 18.4 491.4 57.8 29.1 117.8 287.1 21.5 246.8 40.5 3.4 97.7 142.3 85.4 123.4 217.7 177.9 11.3 70.7 230.5 32.8 14.9 30.7 92.6 39.5 16.6 478.7 284.7 9.7 2.9 20.2 31.2 99.6 1157.2 2331.5 3.9 927.1 586.3 231.7 80.7 16.2 62.8 0.1 75.1 522.2 183.6 4.3 13.5 2.3 19.5 0.5 14.9 0.0 3.7 5.2 1025.3 0.3 2.2 1711.4 1.0 578.6 7.8 20.9 5.6 0.2 0.7 0.6 60.9 1.4 0.3 3.2 22.4 13.4 263.2 0.1 19.5 4.3 1.6 11.1 1.0 39.9 87.6 1.1 17.9 10.4 4.2 4.2 0.5 1297.6 86.7 362.7 358.1 0.6 0.4 0.4 464.1 6.9 116.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 9.0 33.9 20.4 10.3 14.9 23.1 18.4 21.5 11.3 14.9 9.7 74.6 0.0 5.8 26.1 2.5 122.2 11.0 1.5 18.2 18.9 9.2 35.9 42.7 5.7 4.4 9.2 0.0 11.6 2.3 0.6 3.9 23.2 4.6 20.9 578.3 50.6 1.8 0.0 27.1 3.3 18.6 816.1 6.1 16.1 1.3 48.7 101.0 13.4 22.4 15.2 8.2 0.3 0.0 3.3 134.7 18.6 353.0 7.8 147.7 40.3 2.0 18.7 0.0 30.7 2.4 6.1 2.6 251.3 3.5 6.3 2.1 10.3 1.0 4.3 184.1 152.3 324.4 2.6 6.2 5.5 89.9 20.8 13.7 246.5 1.4 3.8 COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 10.2;Cardiomyocytes: 13.5;Fibroblasts: 13.4;Macrophages: 6.8;Melanocytes: 7.2;Microglial cells: 8.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 5.8;fHDF/TERT166: 4.3;HHSteC: 14.1;hTERT-RPE1: 18.2;THP-1: 4.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.6" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" 5.2 1.2 2.5 4.4 2.2 0.5 5.6 6.1 2.4 9.0 18.3 5.9 1.4 5.7 1.6 5.8 4.2 4.8 5.4 2.3 2.9 1.1 0.6 4.6 3.1 9.0 4.2 3.3 0.8 0.7 4.0 12.8 7.1 6.1 2.0 0.4 7.4 11.4 0.6 5.5 2.4 3.7 6.1 8.5 9.1 0.9 4.2 4.9 7.5 2.1 3.5 13.3 5.9 5.7 0.0 0.0 0.0 0.0 0.5 1.0 0.1 5.8 1.7 1.6 0.9 0.2 0.1 0.0 0.8 4.3 0.0 0.3 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.1 14.1 0.0 0.0 1.7 0.1 0.7 0.0 18.2 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.4 0.1 0.1 0.0 0.5 0.5 0.5 0.0 0.2 0.4 0.0 4.7 0.1 2.3 0.3 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.5 2.2 6.1 2.4 2.3 2.9 9.0 4.2 7.1 6.1 4.2 5.7 0.6 0.0 1.8 0.3 0.0 2.2 2.2 1.8 0.0 0.1 1.3 10.2 13.5 0.0 0.7 0.0 0.0 0.4 1.4 0.0 0.0 0.4 0.1 0.2 0.2 0.7 0.0 0.0 0.2 0.2 0.3 13.4 0.5 0.3 2.5 0.5 1.1 0.0 6.2 0.0 0.4 0.0 0.0 2.0 2.7 0.2 3.1 6.8 7.2 8.4 1.2 0.3 0.0 0.5 0.1 0.6 0.0 6.0 0.1 5.3 0.0 0.0 0.2 0.2 6.6 0.7 1.4 0.0 0.3 0.1 1.3 0.8 1.2 0.3 0.0 0.4 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COPZ2 MGC23008 ENSG00000005243 "COPI coat complex subunit zeta 2" Q9P299 17 48026167-48038030 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 49.8;Endometrial stromal cells: 63.8;Fibroblasts: 77.7;Leydig cells: 50.4;Smooth muscle cells: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 167.4;ASC TERT1: 185.6;BJ: 127.1;BJ hTERT+: 133.1;fHDF/TERT166: 271.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055999 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA055999: AB_2683003" "unprognostic (2.66e-1)" "unprognostic (9.32e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (6.28e-2)" "unprognostic (1.12e-1)" "unprognostic (2.77e-2)" "unprognostic (1.59e-1)" "unprognostic (9.34e-2)" "unprognostic (2.49e-1)" "unprognostic (7.02e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (3.45e-9)" "unprognostic (7.42e-3)" "unprognostic (2.76e-2)" "prognostic unfavorable (2.89e-6)" "prognostic unfavorable (4.66e-4)" 71.7 28.6 11.8 11.7 12.6 1.0 46.4 13.0 19.1 41.8 22.8 57.0 6.2 38.3 21.4 15.9 32.6 22.9 57.1 12.4 16.4 19.2 33.2 22.1 5.8 15.3 12.5 13.6 19.7 24.3 14.8 22.5 15.1 34.2 14.7 5.1 23.4 36.8 90.8 35.3 18.2 45.6 14.0 11.7 27.1 11.6 13.1 4.9 32.1 48.6 6.9 37.3 33.1 15.7 38.7 7.5 4.1 0.0 167.4 185.6 0.0 127.1 133.1 35.0 38.6 0.0 4.4 0.0 28.3 271.6 0.0 39.5 0.0 0.5 34.9 1.7 0.1 13.6 21.3 0.1 68.4 0.0 0.8 111.7 16.0 26.2 3.5 41.1 5.3 0.3 0.1 0.8 86.9 18.1 0.4 0.0 0.2 2.6 2.5 0.0 0.0 6.1 2.4 0.0 0.2 5.7 24.6 0.0 28.3 1.0 6.0 4.2 34.4 91.5 14.5 72.9 0.5 91.6 11.1 1.3 99.3 0.0 13.1 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.1 11.8 12.6 13.0 19.1 12.4 16.4 15.3 12.5 15.1 14.0 13.1 15.7 31.6 9.6 2.2 8.1 2.6 49.8 16.7 9.4 9.1 1.2 7.3 30.1 37.1 0.0 1.4 7.3 0.0 1.0 7.5 0.4 11.7 1.0 7.0 2.1 63.8 15.6 0.0 0.0 1.4 5.1 1.2 77.7 0.0 1.5 1.3 2.7 16.4 39.0 6.9 0.0 1.7 2.3 2.0 4.4 28.4 21.1 50.4 3.4 28.4 7.5 0.8 34.8 4.1 2.5 7.6 2.5 0.0 41.8 3.5 6.0 0.1 19.1 0.6 1.3 6.6 21.6 49.2 14.1 3.7 3.1 26.0 2.3 3.7 8.5 0.4 11.7 COX7A1 "COX7A, COX7AH" ENSG00000161281 "Cytochrome c oxidase subunit 7A1" P24310 19 36150922-36152449 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 18 "heart muscle: 2260.5;skeletal muscle: 6947.0;tongue: 4960.0" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 21879.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 162.5;ASC TERT1: 122.3;BJ: 84.7;BJ hTERT+: 102.7;fHDF/TERT166: 178.6;HHSteC: 91.4;HSkMC: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (5.48e-2)" "unprognostic (1.19e-1)" "unprognostic (6.13e-3)" "unprognostic (6.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.41e-1)" "unprognostic (9.49e-2)" "unprognostic (1.46e-1)" "unprognostic (7.84e-3)" "unprognostic (7.27e-3)" "unprognostic (9.44e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-2)" 269.2 91.5 197.5 20.4 198.8 2.1 105.9 195.3 256.5 70.6 197.2 122.8 14.9 54.6 39.3 82.3 57.8 31.9 2260.5 210.0 214.7 86.9 11.9 63.3 12.0 197.7 188.7 46.0 40.6 147.8 105.6 27.4 199.5 86.6 23.7 49.7 88.0 119.1 6947.0 33.8 36.7 85.1 192.1 34.4 46.7 9.7 200.0 85.8 54.8 4960.0 7.3 88.5 50.1 217.9 0.5 5.9 0.6 0.1 162.5 122.3 0.0 84.7 102.7 3.4 0.0 0.0 1.8 1.4 13.0 178.6 0.0 0.7 0.0 0.0 0.8 0.2 1.8 0.4 2.1 0.3 91.4 0.0 0.8 109.0 0.0 0.0 0.0 0.0 11.3 0.0 0.6 0.7 0.0 0.8 0.0 0.7 1.0 0.6 1.2 0.2 0.0 0.4 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.2 0.6 0.1 20.7 0.0 1.3 0.5 0.4 0.8 1.9 0.7 0.2 0.8 1.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 197.5 198.8 195.3 256.5 210.0 214.7 197.7 188.7 199.5 192.1 200.0 217.9 309.7 0.0 5.1 2.3 2.2 26.4 1.0 28.2 2.8 80.6 25.0 89.4 21879.1 18.6 11.0 22.0 45.9 1.0 1.5 0.0 817.8 13.7 17.0 6.0 124.6 360.4 0.0 5.3 5.9 14.1 0.7 602.1 0.5 3.7 45.0 5.5 259.5 7.3 24.0 67.3 4.3 0.0 26.4 10.7 30.5 90.8 224.6 5.2 284.6 3.7 0.0 31.5 0.0 2.0 2.3 6.2 0.0 281.3 1.5 3.5 0.0 183.1 10.7 84.7 184.1 328.4 463.4 2.0 3.8 4.3 19.0 1.9 4.8 17.3 0.1 0.8 CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 112.0;lung: 86.3" "Cell type enriched" "Detected in some" 26 "granulocytes: 4422.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1534 "basophil: 1115.4" "Lineage enriched" "Detected in single" 5518 "granulocytes: 1115.4" "Cell line enriched" "Detected in some" 45 "HEL: 303.3" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" 18.2 2.6 0.0 19.9 0.4 25.7 20.9 0.0 0.0 59.4 0.3 39.2 27.3 26.1 19.3 41.1 6.6 112.0 6.2 0.0 0.0 3.3 2.7 86.3 11.2 0.0 0.0 0.9 21.0 2.8 0.9 1.7 0.0 18.5 56.6 0.0 12.1 15.1 1.6 17.7 45.9 25.7 0.0 1.1 45.3 3.8 0.0 14.9 0.9 10.2 15.1 54.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 303.3 0.0 0.0 0.2 0.2 6.7 0.2 0.0 0.1 0.3 0.5 3.8 0.0 0.1 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1115.4 0.0 0.7 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.1 163.9 0.0 0.5 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 16.0 0.0 1.6 0.0 3.5 0.5 0.0 4422.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 5.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 6.7 0.3 0.0 0.0 8.7 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.3 0.0 41.7 0.0 0.0 0.3 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;testis: 32.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.0;Inhibitory neurons: 44.3;Oligodendrocytes: 196.5;Spermatocytes: 34.1;Spermatogonia: 62.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-MEL-30: 37.9;U-2197: 106.0;U-87 MG: 39.1" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040396: AB_2676960" "unprognostic (3.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.44e-2)" "unprognostic (1.77e-3)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (3.90e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-2)" "unprognostic (7.51e-3)" "unprognostic (1.97e-3)" "unprognostic (9.50e-3)" "unprognostic (8.17e-2)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" 2.8 5.0 10.4 1.3 18.6 0.2 2.5 20.3 18.6 9.3 4.5 6.8 1.2 4.2 7.9 3.6 8.3 4.0 2.9 12.7 17.0 1.2 0.2 1.6 0.5 21.3 21.7 14.3 1.3 0.8 21.8 0.3 24.0 2.3 2.4 4.5 1.5 3.7 2.4 1.9 2.5 3.4 15.0 0.6 2.5 32.4 20.4 0.4 2.3 10.5 0.5 7.7 6.1 33.6 0.1 3.6 0.3 0.4 2.6 0.2 0.1 2.8 0.3 1.8 1.4 0.2 0.1 0.0 6.3 1.1 19.5 0.1 5.1 0.0 0.4 0.0 4.2 0.1 0.1 0.1 1.8 0.1 2.3 1.4 0.0 3.5 0.0 0.2 0.0 7.6 8.9 0.2 1.3 0.2 0.6 0.1 8.2 0.1 1.0 0.0 0.2 0.1 0.0 0.1 10.5 2.4 9.2 0.5 37.9 11.2 0.1 1.1 0.1 18.9 7.5 106.0 6.0 5.3 14.3 1.4 39.1 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.4 18.6 20.3 18.6 12.7 17.0 21.3 21.7 24.0 15.0 20.4 33.6 0.3 0.0 0.0 19.6 0.1 0.8 0.3 0.0 0.0 11.5 0.6 0.3 1.9 0.0 0.0 0.0 10.4 0.0 0.1 0.1 0.0 0.1 12.6 0.5 1.4 0.2 0.0 0.0 70.0 0.0 0.0 5.9 0.5 0.1 1.3 0.3 0.4 0.0 0.3 11.8 44.3 0.0 0.0 0.0 0.8 20.0 4.1 0.4 5.4 10.3 0.1 5.2 0.0 10.1 196.5 0.1 0.0 2.2 0.2 0.5 0.0 0.4 2.2 4.3 6.6 1.9 1.8 34.1 62.3 0.0 0.6 0.1 0.4 0.0 0.0 0.1 CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1189.7;vagina: 604.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 485.4;Breast glandular cells: 224.2;Club cells: 266.7;Squamous epithelial cells: 714.0;Urothelial cells: 506.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1592.5;MCF7: 625.9;T-47d: 1201.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 36.0" HPA004135 Supported Supported Nucleoplasm,Cytosol NA NA 76000 "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol Nucleoplasm "HPA004135: AB_1846516" "unprognostic (1.17e-2)" "unprognostic (9.30e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (1.75e-2)" "unprognostic (1.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" "unprognostic (6.45e-2)" "unprognostic (7.79e-2)" "unprognostic (7.23e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.19e-13)" "unprognostic (3.05e-3)" "unprognostic (1.34e-1)" "unprognostic (3.86e-2)" "unprognostic (2.25e-2)" 22.2 8.0 9.6 4.8 11.5 5.7 104.5 10.5 18.8 273.7 29.4 13.3 0.9 76.3 4.7 1189.7 83.1 18.2 5.5 10.7 12.8 12.0 2.3 6.4 3.9 8.0 8.2 6.2 3.4 55.1 43.5 40.5 7.8 34.8 4.8 4.5 93.5 57.1 5.0 179.0 3.9 57.0 7.4 7.9 5.6 5.3 12.0 15.5 14.5 1.8 76.2 81.2 604.9 10.1 103.4 5.4 115.3 1.6 147.1 218.0 0.4 215.4 1592.5 17.3 21.3 184.9 369.8 1.6 103.1 234.0 2.2 131.2 28.1 0.8 5.1 2.9 8.1 0.1 13.5 1.6 29.0 0.3 2.5 69.3 10.6 25.4 0.5 13.8 0.7 2.0 1.0 2.2 1.9 625.9 1.7 1.9 136.5 12.3 57.3 1.7 0.8 3.4 2.3 4.0 280.7 20.2 3.0 366.2 1.5 214.9 1201.3 0.7 0.2 4.2 63.1 35.5 13.4 9.8 23.8 1.3 28.6 1.6 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.6 11.5 10.5 18.8 10.7 12.8 8.0 8.2 7.8 7.4 12.0 10.1 7.0 0.0 2.6 1.3 1.8 65.0 131.2 485.4 104.2 1.8 224.2 96.8 0.7 1.5 266.7 16.5 2.1 53.9 4.9 0.9 0.0 12.6 2.2 18.0 51.9 10.3 0.0 0.0 3.1 5.2 6.2 168.4 1.1 29.3 0.0 0.5 6.4 0.2 10.0 0.0 1.8 0.9 40.7 0.0 55.4 1.0 19.9 3.9 62.2 0.0 0.0 1.0 0.0 1.5 0.3 18.1 0.2 37.6 0.2 194.9 0.1 0.3 28.2 0.6 0.0 4.3 40.0 2.0 6.1 714.0 190.7 18.1 7.6 4.8 1.7 506.4 CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.9;Pancreatic endocrine cells: 149.9;Paneth cells: 177.3;Suprabasal keratinocytes: 139.5;Urothelial cells: 243.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 20 "B-cells: 3.1;T-cells: 9.2" "Cell line enhanced" "Detected in some" "A-431: 57.9;BEWO: 35.1;CACO-2: 38.1;HaCaT: 36.9;hTCEpi: 27.8;OE19: 33.1;SK-BR-3: 29.5;T-47d: 25.8" "Low region specificity" "Detected in many" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" 0.8 0.4 0.3 4.0 0.7 0.3 5.1 1.2 0.5 9.3 6.1 26.9 36.9 2.2 4.6 54.5 8.2 8.2 0.3 0.3 0.2 34.1 32.5 19.0 0.9 0.4 0.2 0.4 44.0 20.7 15.9 3.5 0.5 9.1 10.5 0.4 24.8 8.9 0.1 41.9 30.6 0.5 0.1 0.8 31.1 0.4 0.2 0.8 16.2 0.0 5.4 6.4 17.6 0.5 57.9 7.0 0.0 0.2 0.0 0.1 35.1 0.0 0.0 0.0 0.0 38.1 23.8 0.3 22.1 0.0 0.3 36.9 0.4 12.5 0.0 0.0 0.4 0.1 0.2 21.5 0.0 0.1 0.1 0.0 27.8 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 15.1 0.2 0.4 1.3 33.1 0.0 0.0 0.0 0.7 16.5 24.0 0.0 0.1 0.2 29.5 0.1 1.7 25.8 0.2 0.0 0.1 0.4 0.2 0.1 0.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 1.3 3.1 4.6 2.2 0.0 1.0 9.2 3.6 0.3 0.0 0.0 0.0 3.4 1.9 0.3 0.7 1.2 0.5 0.3 0.2 0.4 0.2 0.5 0.1 0.2 0.5 0.2 35.3 38.0 0.0 2.2 72.1 64.6 81.3 21.1 0.0 43.6 19.9 0.3 71.4 64.0 31.3 0.0 28.1 0.9 160.9 46.9 113.0 0.0 43.8 4.0 1.8 16.8 3.2 0.1 101.5 9.8 2.0 34.7 58.3 1.3 0.1 0.4 31.8 2.5 0.0 0.0 60.2 63.1 1.0 6.2 0.0 0.0 1.3 7.2 0.0 2.7 0.9 0.0 0.0 0.1 149.9 177.3 0.0 3.1 94.4 86.8 44.5 36.3 0.5 0.0 0.0 4.2 1.1 0.4 45.0 139.5 56.2 3.2 0.2 52.0 243.6 CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 49.9;Breast myoepithelial cells: 40.1;Intestinal goblet cells: 56.9;Prostatic glandular cells: 49.3" "Group enriched" "Detected in all" 5 "breast cancer: 47.8;endometrial cancer: 28.7;prostate cancer: 109.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 81.8;OE19: 82.7;SK-BR-3: 174.6;T-47d: 139.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: AB_10669516" "unprognostic (1.35e-1)" "unprognostic (4.71e-2)" "unprognostic (8.13e-3)" "prognostic favorable (7.21e-4)" "unprognostic (2.04e-1)" "unprognostic (1.40e-2)" "unprognostic (5.51e-3)" "unprognostic (5.02e-2)" "unprognostic (1.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.62e-1)" "unprognostic (1.70e-1)" "unprognostic (7.12e-3)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (9.34e-3)" 6.3 8.5 3.5 4.5 3.8 7.6 48.2 4.6 4.7 30.5 4.4 11.5 11.4 12.9 13.0 8.2 19.2 6.7 5.0 3.3 3.5 10.5 14.0 5.8 5.9 3.9 4.1 17.4 13.2 6.7 6.1 6.3 3.7 106.2 15.2 4.9 43.9 7.6 5.6 10.2 9.0 5.7 3.9 7.5 29.3 5.3 3.6 12.0 11.3 5.3 7.4 6.8 6.9 4.7 7.5 10.6 9.8 10.9 6.9 10.0 24.7 6.2 7.2 8.3 7.3 5.1 31.0 13.9 31.7 2.6 6.1 12.0 14.5 9.7 4.5 11.4 5.9 10.3 11.7 8.9 5.6 4.9 8.5 10.9 9.2 7.9 17.9 7.5 7.4 16.5 8.1 16.9 3.8 81.8 9.3 3.8 6.7 82.7 12.7 20.9 10.3 26.1 9.0 5.3 18.5 20.1 6.6 174.6 16.8 12.8 139.9 14.9 4.5 2.5 7.3 5.2 4.9 31.4 17.3 10.6 5.3 8.5 8.2 1.5 2.9 2.2 3.4 1.2 4.5 4.5 1.9 2.4 5.0 4.8 1.8 3.5 0.1 9.4 1.7 5.7 1.8 2.5 3.5 3.8 4.6 4.7 3.3 3.5 3.9 4.1 3.7 3.9 3.6 4.7 7.2 6.4 13.1 3.6 6.2 2.9 13.1 10.1 6.8 5.3 49.9 40.1 2.0 7.2 20.3 1.8 2.1 12.9 5.6 3.6 9.8 14.0 0.4 10.6 5.2 6.9 9.0 8.6 0.4 13.3 17.0 4.8 10.7 13.5 5.7 8.7 4.2 14.2 5.4 0.0 0.4 56.9 6.1 7.5 2.0 0.6 7.2 5.1 5.4 0.0 2.8 6.6 8.2 1.5 2.2 7.9 4.3 2.2 5.3 49.3 4.0 4.1 16.6 8.8 19.7 3.1 5.0 7.4 10.6 6.3 3.0 4.2 4.5 7.6 10.9 7.0 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CRTAM CD355 ENSG00000109943 "Cytotoxic and regulatory T cell molecule" O95727 11 122838500-122872643 "CD markers, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.2" "Group enriched" "Detected in some" 4 "dendritic cells: 63.8;Plasma cells: 16.0;T-cells: 54.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 38.2" "Immune cell enhanced" "Detected in many" "NK-cell: 54.0" "Group enriched" "Detected in many" 4 "NK-cells: 54.0;T-cells: 33.3" "Cell line enriched" "Detected in single" 34 "SCLC-21H: 12.9" "Region enriched" "Detected in some" 44 "cerebellum: 102.6" "Region enriched" "Detected in all" 7 "cerebellum: 25.7" NA NA 6800000 "Cluster 48: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.51e-3)" "unprognostic (6.73e-4)" "unprognostic (1.33e-2)" "unprognostic (3.73e-3)" "unprognostic (2.40e-2)" "unprognostic (5.25e-4)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.32e-1)" "unprognostic (1.83e-4)" "unprognostic (6.01e-2)" "unprognostic (4.26e-2)" "unprognostic (3.87e-2)" "unprognostic (6.59e-2)" 0.3 0.3 0.3 2.3 0.5 1.8 0.5 38.2 1.4 0.3 0.3 0.5 0.6 0.8 0.5 0.3 0.3 1.5 0.2 0.2 0.4 0.1 1.0 1.8 8.8 1.1 1.4 0.3 0.1 0.1 0.1 0.2 4.2 0.3 0.6 0.0 0.7 0.2 0.1 0.3 1.2 0.2 0.5 3.6 0.8 0.2 0.7 4.9 0.2 0.0 3.5 0.8 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 4.6 0.6 13.0 5.6 12.9 0.1 1.5 27.0 3.6 0.2 4.3 33.3 1.2 54.0 10.5 0.2 0.1 6.0 0.3 0.5 38.2 1.4 0.2 0.4 1.1 1.4 4.2 0.5 0.7 1.6 1.1 0.0 1.1 0.3 0.8 1.5 0.4 0.1 0.0 0.0 0.4 0.9 0.3 0.0 0.0 0.0 0.0 0.1 63.8 0.1 0.0 0.0 1.2 0.4 0.4 0.3 0.0 0.4 0.5 0.0 0.2 1.6 2.0 0.6 1.3 0.0 0.4 0.2 5.9 0.0 0.7 0.0 0.0 8.8 8.1 1.2 0.0 10.3 3.6 0.0 9.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.3 0.5 0.0 0.9 0.1 54.1 0.0 0.0 0.5 CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.6" "Group enriched" "Detected in all" 5 "dendritic cells: 306.9;monocytes: 377.6" "Cell line enhanced" "Detected in all" "ASC diff: 795.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" 157.2 106.5 65.2 38.7 69.2 43.2 123.9 51.9 54.8 211.2 52.9 145.1 35.0 170.1 57.1 58.7 138.3 80.5 83.9 49.6 64.9 67.9 44.6 92.3 37.3 65.2 62.4 131.4 36.0 45.7 22.8 69.9 63.9 90.7 51.6 19.3 54.0 106.5 54.4 84.1 65.6 115.0 67.5 48.2 78.9 25.0 65.3 23.7 77.2 68.9 38.1 142.7 135.8 69.5 64.1 123.3 37.8 119.2 795.0 516.6 219.0 136.1 294.0 160.6 151.9 42.1 35.1 44.4 147.6 259.3 129.9 80.2 68.0 103.9 115.5 110.1 106.0 69.2 87.6 43.7 237.4 45.4 54.8 415.3 208.5 145.0 183.2 311.7 172.0 27.0 60.3 82.1 164.6 54.7 16.5 46.3 45.5 67.5 165.7 59.4 111.0 86.1 127.8 42.0 7.9 61.0 92.0 79.8 201.1 87.3 85.9 109.3 113.0 209.1 89.1 115.4 145.9 59.0 214.3 6.7 164.3 89.7 117.1 13.4 377.6 28.5 35.8 147.7 52.5 39.9 51.4 40.2 306.9 39.2 29.2 27.8 30.5 42.1 46.0 82.5 74.0 200.5 65.2 69.2 51.9 54.8 49.6 64.9 65.2 62.4 63.9 67.5 65.3 69.5 74.0 9.6 42.8 15.3 29.0 60.4 41.1 39.5 150.8 17.9 32.7 43.7 34.7 25.8 22.0 38.6 8.4 49.0 37.1 14.8 11.7 25.0 1.2 17.4 135.7 72.7 6.0 46.0 10.0 32.0 81.6 142.3 29.0 31.2 48.1 58.4 122.4 53.2 107.0 35.3 14.5 26.0 10.2 181.1 91.1 6.3 142.9 108.6 80.0 10.3 134.1 15.9 22.6 17.1 11.6 18.4 16.3 144.8 58.1 24.5 24.4 52.7 6.8 10.1 111.7 78.4 120.9 1.6 15.9 95.1 46.7 28.0 26.5 89.9 36.1 30.0 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CSRP1 "CSRP, CYRP, D1S181E" ENSG00000159176 "Cysteine and glycine rich protein 1" P21291 1 201483530-201509456 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 2743.3;seminal vesicle: 2571.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 341.2;Breast myoepithelial cells: 737.5;Extravillous trophoblasts: 388.5;Smooth muscle cells: 419.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045617 Uncertain NA NA 11000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA045617: AB_2679391" "unprognostic (7.08e-2)" "unprognostic (1.59e-2)" "unprognostic (4.86e-2)" "unprognostic (9.89e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.24e-2)" "unprognostic (2.58e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (2.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.96e-3)" 344.5 127.2 713.6 224.5 871.4 41.0 321.8 742.5 717.3 542.4 467.6 2743.3 180.6 1904.4 308.4 884.1 1025.6 152.7 194.2 647.3 735.1 192.5 114.7 386.0 64.9 840.1 837.4 319.0 114.6 188.0 117.0 118.3 719.0 947.2 432.0 24.2 250.1 2571.3 64.0 219.8 503.6 2009.6 713.5 165.6 748.3 44.2 848.5 48.0 186.4 53.8 65.7 1494.5 469.1 766.6 83.0 195.3 52.0 116.4 83.2 107.7 273.6 605.7 514.3 455.3 360.9 211.1 57.7 78.7 36.1 325.0 96.7 144.7 32.7 120.3 321.2 169.5 29.3 90.7 220.1 30.7 387.4 72.1 10.2 99.3 105.3 373.0 163.1 253.1 508.1 34.9 4.5 71.9 302.1 232.9 46.6 11.8 0.8 99.0 73.2 18.3 304.9 266.8 212.6 129.7 27.1 22.5 238.0 503.8 163.9 25.6 87.0 74.3 610.6 303.7 195.7 206.6 250.6 40.5 82.6 30.6 303.5 137.6 202.6 75.5 49.8 65.6 37.4 49.3 36.9 25.0 35.8 34.9 65.0 18.1 20.5 25.2 5.0 34.3 54.2 5.2 54.1 46.5 713.6 871.4 742.5 717.3 647.3 735.1 840.1 837.4 719.0 713.5 848.5 766.6 151.8 38.5 47.8 86.5 21.8 49.2 341.2 24.6 207.7 3.4 123.7 737.5 24.8 21.5 36.9 47.8 0.0 88.8 23.3 96.6 49.0 165.1 21.5 30.1 73.6 86.9 57.9 19.1 2.4 171.7 388.5 86.7 36.7 38.9 27.9 13.9 91.1 28.3 66.0 0.0 2.1 80.0 14.2 29.1 55.8 44.9 41.0 37.0 126.3 10.3 73.5 137.4 15.5 6.6 114.8 140.5 71.4 292.3 61.5 113.8 97.2 28.4 25.2 3.1 144.7 37.7 419.9 2.4 3.2 75.3 34.9 160.9 31.2 30.4 69.7 103.6 CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "breast: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 37 "breast cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029190 Uncertain "Secreted in female reproductive system" NA NA "Cluster 5: Breast - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA029190: AB_10602804" "unprognostic (2.06e-2)" "unprognostic (2.21e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 372.9;granulocytes: 263.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 308.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Enhanced Nucleoplasm,Centrosome,Cytosol No No "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Centrosome, Cytosol" "HPA004742: AB_1847323, HPA027906: , HPA027907: AB_10601362" "unprognostic (2.81e-1)" "unprognostic (3.42e-1)" "unprognostic (8.80e-2)" "unprognostic (1.88e-3)" "unprognostic (1.93e-1)" "unprognostic (2.55e-2)" "unprognostic (1.44e-1)" "unprognostic (5.11e-2)" "unprognostic (1.02e-1)" "unprognostic (3.79e-2)" "unprognostic (2.56e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-3)" "unprognostic (1.62e-1)" "unprognostic (1.67e-1)" "unprognostic (2.81e-1)" "unprognostic (5.31e-2)" 26.9 16.8 20.9 27.3 22.8 41.8 23.8 21.6 24.8 23.7 23.4 31.8 21.7 27.7 31.1 23.4 25.3 19.8 32.3 22.0 22.4 22.9 46.8 25.3 39.3 22.8 22.3 27.1 17.3 19.7 18.2 22.1 21.7 23.4 23.1 18.8 18.5 30.6 33.3 25.3 25.1 30.6 21.6 54.0 34.8 43.3 22.1 40.1 17.1 20.9 41.2 25.8 20.4 23.6 66.7 60.3 56.7 44.6 40.3 32.8 89.2 41.9 43.7 98.0 86.0 224.8 52.4 73.9 59.6 42.7 94.4 69.8 77.1 98.6 105.3 36.1 38.0 243.0 33.2 110.2 41.8 77.4 308.0 35.1 58.9 55.6 54.8 34.1 59.8 103.8 66.8 29.6 53.5 54.9 127.0 101.4 51.4 74.9 85.8 87.9 109.1 56.3 42.9 55.0 45.1 53.6 72.5 102.3 75.4 52.3 50.6 61.1 44.5 97.4 58.0 64.9 68.8 34.1 46.6 85.5 68.5 48.6 52.7 267.9 77.7 103.3 51.0 103.0 49.1 88.9 49.9 53.8 110.3 83.4 49.8 53.6 16.9 79.9 109.6 86.9 66.2 71.3 20.9 22.8 21.6 24.8 22.0 22.4 22.8 22.3 21.7 21.6 22.1 23.6 28.6 28.9 26.4 21.2 40.0 22.8 32.9 40.7 13.1 26.1 13.0 13.2 39.8 17.2 34.1 18.4 18.8 147.8 40.4 21.1 37.2 34.8 372.9 24.2 24.9 32.5 20.9 43.7 31.6 34.7 69.4 28.7 48.4 21.6 263.6 34.4 44.3 45.2 49.3 18.5 35.6 27.3 42.7 36.0 35.5 131.2 34.2 44.5 26.6 14.0 89.8 32.1 40.2 30.7 39.8 31.9 21.5 33.4 21.6 22.3 34.7 43.1 26.1 25.8 19.7 25.4 48.0 79.4 45.2 10.7 22.4 52.9 38.8 23.7 24.2 20.6 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.7;Glandular and luminal cells: 23.5;Kupffer cells: 41.1;Langerhans cells: 21.4;Macrophages: 45.7;Plasma cells: 22.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "classical monocyte: 21.5;intermediate monocyte: 52.4;non-classical monocyte: 36.9" "Lineage enriched" "Detected in many" 15 "monocytes: 52.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.1;BJ hTERT+ SV40 Large T+: 2.2;BJ hTERT+ SV40 Large T+ RasG12V: 2.2;GAMG: 5.1;RPMI-8226: 4.3;RT4: 2.4;THP-1: 3.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 253000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" 4.0 5.9 1.4 95.5 1.5 1.2 20.7 0.9 2.6 13.2 1.2 10.7 11.2 7.1 0.7 8.0 4.1 10.6 4.4 1.2 1.0 7.8 29.0 35.1 68.0 7.4 1.2 3.0 0.9 17.1 2.1 10.3 10.8 43.9 15.9 0.4 20.1 1.8 1.2 2.0 11.2 15.8 3.4 20.3 19.2 3.0 2.6 35.2 3.7 1.1 17.3 45.1 3.7 1.5 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 6.1 2.2 2.2 0.2 0.1 2.0 0.2 0.0 5.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 4.3 0.1 2.4 0.0 0.0 0.0 0.4 1.3 0.0 0.1 3.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.0 0.0 21.5 0.0 0.0 52.4 0.0 1.4 0.3 0.0 3.5 0.1 0.0 0.0 1.1 0.0 36.9 0.0 0.0 7.6 1.4 1.5 0.9 2.6 1.2 1.0 7.4 1.2 10.8 3.4 2.6 1.5 3.8 0.0 2.2 0.0 2.2 0.9 9.4 52.7 0.6 0.0 2.6 7.0 0.3 1.5 2.8 0.0 0.0 0.1 0.0 2.7 0.0 5.9 2.6 12.5 10.9 8.0 0.0 0.0 0.0 0.0 0.0 6.9 3.1 23.5 1.3 0.0 0.0 0.1 17.3 0.0 0.0 1.0 10.2 41.1 21.4 4.0 0.3 45.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 11.4 6.4 2.6 1.3 0.0 0.0 1.3 12.4 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.9 1.4 CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 780.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3435.4;Basal squamous epithelial cells: 3284.9;Breast myoepithelial cells: 1544.3;Fibroblasts: 2220.8;Glandular and luminal cells: 1201.1;Proximal tubular cells: 3662.8;Suprabasal keratinocytes: 2115.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HAP1: 61.6;hTCEpi: 79.9;RPTEC TERT1: 222.2;SuSa: 115.2;U-2 OS: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" NA NA 800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 33: Fibroblasts - ECM organization" "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" 366.1 5.2 77.6 76.2 84.5 0.6 229.1 70.6 102.7 166.3 74.8 152.4 214.0 6.9 66.6 92.9 32.9 19.8 14.0 83.7 73.8 345.6 58.5 7.4 90.7 72.4 91.0 5.5 11.6 1.9 122.0 170.7 72.4 10.1 181.3 17.5 293.5 17.6 81.1 780.3 247.0 6.3 68.7 87.5 107.3 3.7 90.2 26.6 55.2 36.5 128.5 76.6 96.3 77.9 0.0 0.0 2.7 0.0 0.2 0.2 0.7 2.9 0.8 0.2 0.0 0.0 9.1 0.0 2.7 0.1 3.8 0.2 61.6 1.6 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 79.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 4.0 0.0 0.0 0.2 0.0 1.1 222.2 0.0 1.1 0.7 0.2 0.2 0.0 115.2 0.1 0.0 0.0 0.1 84.9 0.4 0.1 0.3 0.0 0.0 1.4 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 77.6 84.5 70.6 102.7 83.7 73.8 72.4 91.0 72.4 68.7 90.2 77.9 123.8 0.0 1.1 32.7 13.1 3435.4 14.4 276.9 3284.9 245.7 47.5 1544.3 4.1 0.0 5.1 283.3 0.0 35.9 6.1 0.0 563.4 0.0 0.8 45.0 140.8 45.9 0.0 0.0 1.0 0.0 25.4 2220.8 0.5 1201.1 0.0 0.0 43.5 0.2 63.6 6.7 150.8 0.0 240.1 0.9 887.9 1.3 20.8 35.3 439.4 8.4 0.0 6.7 0.0 4.5 4.2 0.1 0.0 0.4 13.3 10.6 0.0 3662.8 2.1 19.0 0.0 889.8 99.2 0.4 5.2 69.3 2115.0 77.2 43.4 0.3 0.1 9.3 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYGB "HGB, STAP" ENSG00000161544 Cytoglobin Q8WWM9 17 76527356-76551175 "Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 104.4" "Cell type enhanced" "Detected in many" "Adipocytes: 94.3;Fibroblasts: 87.6;Leydig cells: 95.7;Melanocytes: 78.2;Sertoli cells: 92.1;Smooth muscle cells: 95.6" "Cancer enhanced" "Detected in all" "melanoma: 34.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 79.6;Hep G2: 61.7;HHSteC: 120.7;HSkMC: 95.4;SH-SY5Y: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017757, HPA061642" Approved Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA017757: AB_1847410, HPA061642: AB_2684573" "unprognostic (6.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.97e-2)" "prognostic favorable (2.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-2)" "unprognostic (3.31e-3)" "unprognostic (2.01e-1)" "unprognostic (7.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.08e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (3.34e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.76e-2)" 79.6 20.8 10.1 12.0 10.7 1.7 55.1 20.6 13.6 27.7 14.1 27.1 21.1 19.6 4.6 12.8 20.4 13.2 104.4 9.5 15.8 12.4 19.0 27.8 7.2 17.5 26.0 13.8 12.8 11.7 10.9 8.9 26.8 29.9 9.3 77.6 14.2 11.0 19.3 19.5 26.6 5.9 10.1 12.2 22.9 5.3 14.3 5.3 50.1 9.6 2.6 50.7 25.6 9.8 0.2 1.1 1.8 0.4 79.6 23.1 26.1 0.7 2.0 0.3 0.9 0.0 0.3 0.2 24.1 2.4 0.3 0.7 0.1 33.7 0.1 0.1 0.2 0.4 0.4 61.7 120.7 0.0 0.0 95.4 7.2 2.5 2.5 0.4 0.3 0.8 0.3 0.1 1.2 0.8 0.2 0.4 0.3 0.0 1.4 0.5 0.3 0.2 0.4 0.1 0.6 129.8 0.1 0.0 2.7 5.9 0.2 0.6 0.2 3.1 1.6 0.3 0.0 1.2 0.3 0.3 0.2 0.3 9.9 0.0 0.1 0.1 0.2 0.1 0.1 1.6 0.1 0.0 0.1 2.2 0.2 0.5 0.9 1.0 0.0 0.0 0.2 0.2 10.1 10.7 20.6 13.6 9.5 15.8 17.5 26.0 26.8 10.1 14.3 9.8 94.3 3.2 2.0 2.0 3.5 10.8 1.3 17.3 3.4 38.5 1.4 5.7 6.1 0.0 6.7 0.0 0.0 1.4 1.9 0.1 0.0 0.8 0.7 2.9 4.2 23.1 0.0 0.0 2.4 0.2 0.6 87.6 1.5 0.7 0.0 0.2 2.2 1.2 0.4 8.4 12.3 0.0 0.0 0.0 13.3 2.5 95.7 2.6 78.2 3.7 0.0 22.1 0.0 1.0 1.0 0.1 0.0 23.3 0.6 0.8 0.0 0.2 21.1 12.9 92.1 21.8 95.6 1.6 1.4 0.7 6.7 2.9 2.6 9.2 0.0 1.0 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CYSTM1 "C5orf32, ORF1-FL49" ENSG00000120306 "Cysteine rich transmembrane module containing 1" Q9H1C7 5 140175156-140282052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 1317.5" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2568.9;Gastric mucus-secreting cells: 2148.3;Late spermatids: 1327.7;Pancreatic endocrine cells: 1331.5;Proximal tubular cells: 1301.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 425.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 425.2" "Cell line enhanced" "Detected in all" "OE19: 773.7;RPTEC TERT1: 364.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050930 Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA050930: AB_2681278" "unprognostic (7.39e-2)" "unprognostic (3.68e-2)" "unprognostic (4.46e-2)" "prognostic favorable (1.31e-4)" "unprognostic (5.38e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.69e-5)" "unprognostic (7.63e-2)" "unprognostic (2.23e-1)" "unprognostic (4.67e-2)" "unprognostic (1.14e-2)" 86.3 187.3 111.3 53.7 112.6 161.2 61.1 114.2 131.5 48.5 148.6 184.3 320.5 36.6 53.9 28.3 139.6 150.8 114.6 110.2 121.1 264.8 74.4 96.6 23.4 117.9 117.4 29.1 141.3 128.6 53.9 64.6 119.3 31.3 166.2 35.2 81.7 41.7 293.5 23.8 168.0 60.0 112.7 33.4 1317.5 35.7 116.4 31.7 87.2 360.0 20.9 158.1 21.9 112.5 68.5 118.8 10.1 65.8 152.5 118.2 51.0 26.7 77.1 34.5 67.8 142.0 115.1 28.4 92.2 44.8 180.1 42.8 55.7 70.8 27.5 54.3 74.6 2.7 50.4 92.3 119.1 9.1 63.5 31.4 92.2 42.2 77.0 62.7 67.5 91.1 48.7 68.4 8.2 66.2 31.4 16.6 16.4 773.7 44.5 7.0 12.4 51.4 364.9 284.0 25.4 16.6 45.8 28.8 280.6 33.3 96.9 27.0 16.0 17.0 17.1 12.8 31.8 62.5 48.6 26.4 87.9 8.9 32.8 15.6 32.4 22.4 4.3 37.3 8.1 18.2 11.5 7.2 41.3 14.4 3.1 4.8 425.2 4.5 39.1 64.0 17.2 16.4 111.3 112.6 114.2 131.5 110.2 121.1 117.9 117.4 119.3 112.7 116.4 112.5 259.9 317.3 115.2 34.6 52.8 169.5 525.6 252.8 51.2 5.6 85.5 77.8 107.2 424.7 186.1 573.8 2.1 422.8 42.8 1024.7 2568.9 674.9 444.3 469.0 60.8 147.8 435.8 47.4 10.6 846.6 53.6 174.0 2148.3 218.9 119.2 9.4 120.0 88.5 205.2 11.8 12.5 285.8 205.4 45.3 150.0 1327.7 101.5 77.1 394.8 13.1 105.5 153.3 3.1 4.5 11.1 1331.5 1148.5 116.6 37.4 365.1 727.1 1301.6 576.5 18.8 144.7 115.6 190.6 208.6 81.4 28.4 113.7 393.1 53.9 30.2 429.3 736.7 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 CYTIP "B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP" ENSG00000115165 "Cytohesin 1 interacting protein" O60759 2 157414619-157488961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 105.6;lymphoid tissue: 114.3" "Cell type enhanced" "Detected in many" "B-cells: 240.4;dendritic cells: 244.3;Langerhans cells: 552.9;Macrophages: 164.0;monocytes: 490.1;NK-cells: 181.3;Plasma cells: 392.5;T-cells: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 54.6;HDLM-2: 44.3;Karpas-707: 146.4;RPMI-8226: 46.9;U-266/70: 246.5;U-266/84: 99.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA007191 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA007191: AB_1855801" "unprognostic (3.61e-3)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (9.12e-4)" "unprognostic (5.71e-2)" "unprognostic (1.36e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (6.12e-2)" "unprognostic (7.41e-2)" "unprognostic (1.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (5.49e-2)" "unprognostic (5.43e-2)" "unprognostic (3.78e-2)" 9.2 2.7 1.4 70.0 1.7 105.6 7.7 1.5 3.7 5.7 4.0 12.8 27.3 3.2 2.1 6.9 3.4 11.8 4.1 1.4 1.9 5.2 12.3 26.1 91.5 3.1 1.8 1.5 3.4 0.9 1.4 4.4 2.6 3.3 14.6 0.5 14.3 3.9 1.1 2.8 23.1 7.0 2.5 42.2 41.6 2.5 2.3 53.6 4.0 2.2 114.3 20.8 3.7 3.2 0.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 54.6 0.1 0.6 0.0 0.1 0.0 0.0 0.1 44.3 0.0 0.3 0.0 0.0 0.0 7.8 6.4 0.0 0.0 0.2 0.0 4.0 0.0 0.2 0.0 146.4 0.7 0.0 0.0 6.3 0.3 0.8 0.1 0.0 0.1 46.9 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 2.0 0.2 246.5 99.8 24.1 2.4 6.8 0.0 248.9 37.6 109.9 121.8 122.5 122.5 91.5 127.9 115.7 56.1 91.6 205.5 161.0 203.6 90.2 247.9 28.1 136.5 154.8 1.4 1.7 1.5 3.7 1.4 1.9 3.1 1.8 2.6 2.5 2.3 3.2 3.2 3.2 12.2 0.0 240.4 20.9 1.0 0.0 0.6 0.0 24.4 2.5 2.1 5.7 1.3 1.8 0.0 0.7 244.3 0.6 15.6 0.3 1.4 0.3 0.4 4.5 1.8 14.9 0.1 1.9 13.6 6.4 29.0 0.8 7.0 0.0 6.8 1.7 25.2 0.0 0.1 3.7 0.0 86.1 552.9 2.0 0.0 164.0 83.6 12.2 490.1 0.0 181.3 0.0 0.0 0.3 0.3 0.0 392.5 0.7 0.4 1.1 0.0 0.1 0.0 1.5 4.5 0.0 0.6 1.2 17.8 3.0 366.6 0.0 3.8 0.5 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 92.0;skeletal muscle: 48.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 16.0;Exocrine glandular cells: 18.8;Horizontal cells: 30.3;Pancreatic endocrine cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Cell line enhanced" "Detected in many" "MCF7: 139.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nuclear speckles" Cytosol "HPA043018: AB_10794921" "unprognostic (1.07e-1)" "unprognostic (8.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-2)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (6.07e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "prognostic favorable (2.75e-7)" "unprognostic (1.03e-1)" "unprognostic (5.67e-1)" "unprognostic (2.44e-2)" "unprognostic (2.00e-2)" 1.8 7.4 47.1 2.5 35.3 0.3 4.4 27.5 60.6 4.1 11.6 2.9 1.6 0.9 10.0 28.2 3.6 3.8 4.6 35.2 40.7 13.3 6.5 3.5 4.7 50.6 55.3 3.1 19.5 9.6 7.7 0.1 50.8 3.8 1.4 7.4 15.5 3.1 48.0 6.0 1.7 1.3 30.3 1.2 7.7 1.0 92.0 1.4 5.2 4.8 5.1 1.7 7.3 38.6 22.8 34.7 3.5 44.7 0.9 0.4 24.7 4.9 6.6 10.5 5.3 32.1 19.7 0.0 2.7 1.1 10.2 24.0 41.3 1.2 10.7 0.1 65.4 0.0 4.4 58.6 1.5 0.3 4.7 1.0 3.3 18.8 0.1 25.2 47.3 0.8 6.7 0.4 4.1 139.7 0.1 33.5 59.5 18.6 13.9 14.5 32.3 0.6 64.2 4.5 51.2 53.0 5.6 5.3 44.8 10.2 34.6 4.8 36.2 7.4 15.1 0.4 24.1 0.3 0.3 0.4 3.5 3.9 20.1 0.0 0.0 0.7 0.0 0.0 0.0 1.2 0.6 0.5 0.0 12.9 2.9 0.5 0.0 0.0 0.0 0.1 0.0 1.0 47.1 35.3 27.5 60.6 35.2 40.7 50.6 55.3 50.8 30.3 92.0 38.6 0.3 3.2 2.0 2.9 6.0 0.4 0.6 0.6 0.0 1.8 13.5 7.5 2.5 22.8 2.0 9.2 0.0 0.2 0.1 1.4 9.8 16.0 0.0 5.7 0.7 1.1 6.0 0.0 6.1 18.8 0.3 0.2 2.6 7.8 0.0 3.4 1.4 2.5 0.3 30.3 3.6 1.5 2.0 0.0 0.7 0.0 1.2 0.1 3.6 2.8 0.2 10.4 0.0 1.5 0.7 15.0 2.9 0.4 0.5 4.3 0.2 10.8 2.7 1.8 0.0 1.4 1.2 0.1 2.0 8.1 1.0 0.0 1.4 0.3 0.8 1.3 DBNDD2 "C20orf35, HSMNP1" ENSG00000244274 "Dysbindin domain containing 2" Q9BQY9 20 45406057-45410610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1300.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 18.8;Gastric mucus-secreting cells: 20.4;Macrophages: 10.7;Smooth muscle cells: 23.6;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "dendritic cells: 18.7;monocytes: 12.5;T-cells: 9.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043991 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA043991: AB_10966212" "unprognostic (6.33e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.79e-3)" "unprognostic (2.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-3)" "unprognostic (8.24e-2)" "unprognostic (5.44e-2)" "unprognostic (3.06e-1)" "unprognostic (3.71e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-3)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.52e-2)" "unprognostic (3.48e-1)" 71.5 29.7 627.6 33.6 916.1 7.1 59.4 827.6 1054.5 73.6 462.6 160.9 54.5 106.6 41.7 58.7 102.7 33.1 470.5 645.7 709.8 56.3 10.4 63.1 21.3 871.6 808.2 39.1 39.9 65.3 41.3 42.9 853.0 70.2 91.1 34.9 47.7 89.4 316.2 68.6 78.4 100.9 739.9 30.3 82.2 14.4 822.1 23.2 37.2 248.2 27.3 118.7 69.7 1300.9 78.0 13.6 10.8 76.3 6.8 3.0 15.0 44.7 48.4 36.7 24.8 37.2 103.4 1.1 7.7 44.4 13.9 112.1 74.7 4.0 22.4 0.6 43.9 64.5 57.0 34.3 43.1 3.5 94.0 1.2 12.6 13.9 12.8 63.5 25.3 64.8 4.7 1.5 2.9 99.0 5.6 4.9 14.0 50.8 80.0 0.3 1.0 0.7 105.3 1.4 24.8 12.7 15.6 8.4 99.3 7.6 104.0 19.9 41.1 1.5 72.5 48.8 49.5 1.1 1.6 0.3 5.3 0.6 10.9 0.0 10.4 0.0 9.1 12.5 3.3 0.2 8.0 6.8 7.6 0.3 7.4 6.9 0.5 0.8 7.2 18.7 7.4 4.5 627.6 916.1 827.6 1054.5 645.7 709.8 871.6 808.2 853.0 739.9 822.1 1300.9 0.3 3.2 0.5 0.0 3.3 0.0 0.2 0.1 18.8 0.0 0.6 0.3 1.0 0.0 2.5 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.3 0.4 0.2 2.7 0.0 2.1 0.0 0.0 0.0 7.3 20.4 0.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 10.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.5 0.0 3.9 0.4 0.9 0.0 5.3 0.0 0.0 0.6 23.6 0.1 0.0 32.7 0.6 0.0 5.3 0.1 0.4 0.3 DDRGK1 "C20orf116, dJ1187M17.3, UFBP1" ENSG00000198171 "DDRGK domain containing 1" Q96HY6 20 3190350-3204685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013373, HPA013705" Approved Supported "Nucleoli,Endoplasmic reticulum" NA NA 24000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" Nucleoli "HPA013373: AB_2091955, HPA013705: AB_2668872" "unprognostic (2.99e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (6.54e-3)" "unprognostic (2.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.63e-1)" "unprognostic (4.10e-3)" "unprognostic (8.16e-2)" "unprognostic (5.44e-3)" "unprognostic (7.29e-2)" "prognostic favorable (2.01e-5)" "unprognostic (6.80e-3)" "unprognostic (1.43e-2)" "unprognostic (2.48e-2)" "unprognostic (6.90e-2)" 44.6 89.1 43.2 23.8 44.6 24.8 45.5 38.9 65.7 50.8 36.7 43.3 43.4 43.5 20.0 46.0 49.0 22.4 38.4 42.3 36.8 51.2 77.9 51.6 23.6 39.7 38.8 48.9 84.1 54.7 36.6 25.9 39.5 45.7 19.2 43.2 61.7 32.2 58.2 53.0 44.9 19.9 33.5 36.3 63.0 34.8 37.5 18.6 51.3 14.1 17.0 43.5 44.6 48.4 108.5 133.3 32.3 60.6 71.7 27.2 46.6 67.2 31.9 40.6 44.1 105.7 76.7 64.3 53.6 37.5 77.9 118.2 33.5 100.6 14.8 44.0 62.8 54.4 45.6 186.1 97.9 62.1 56.6 42.8 96.2 77.8 55.2 44.8 37.5 45.3 77.0 74.8 26.4 59.2 42.9 115.5 40.1 73.6 60.8 55.9 28.7 98.6 66.7 99.8 71.4 44.1 69.2 192.7 65.6 19.2 82.0 37.6 57.2 64.9 28.8 46.3 104.2 55.8 67.7 27.3 18.0 51.6 38.9 23.1 36.9 45.6 33.3 25.3 32.7 26.9 35.0 35.6 36.8 26.3 30.8 30.5 9.5 24.6 23.2 57.3 36.2 25.9 43.2 44.6 38.9 65.7 42.3 36.8 39.7 38.8 39.5 33.5 37.5 48.4 57.3 44.8 53.9 19.9 35.1 26.3 68.8 119.0 44.3 47.9 77.1 72.3 31.3 91.5 114.3 69.9 64.6 127.5 50.9 105.8 19.6 147.0 42.2 54.8 42.6 54.1 53.4 26.5 28.6 178.8 65.1 49.3 54.0 79.0 27.3 34.8 50.0 125.6 119.3 52.2 13.9 72.2 154.6 60.9 36.0 21.1 55.9 54.2 39.2 7.5 67.8 73.7 64.9 6.0 28.4 145.0 125.3 68.8 60.5 75.7 216.3 80.5 81.6 108.3 65.7 39.1 115.6 38.7 23.6 64.0 38.8 146.0 44.7 70.0 92.7 75.0 DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.0;intestine: 34.8;skin 1: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 82.8;Paneth cells: 77.0;Proximal enterocytes: 298.9;Respiratory ciliated cells: 144.8;Squamous epithelial cells: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.6;memory B-cell: 10.9;naive B-cell: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.6" "Group enriched" "Detected in some" 16 "OE19: 69.3;T-47d: 104.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" 0.4 0.1 6.4 1.0 7.2 0.2 6.1 18.3 7.1 4.8 3.6 8.9 24.7 3.3 0.5 37.0 2.0 6.5 0.2 5.1 4.5 10.8 0.9 1.6 0.6 5.9 5.3 1.0 6.9 0.4 3.3 0.4 6.0 2.3 4.5 0.2 8.6 2.1 0.3 54.2 34.8 0.5 4.8 0.8 20.1 1.1 5.3 0.1 2.4 0.0 1.8 6.5 10.1 4.9 0.0 0.3 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 2.4 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.5 0.8 0.1 0.3 0.0 0.0 0.0 0.0 1.1 1.6 0.0 0.0 4.2 0.4 0.3 0.1 69.3 0.0 0.4 0.0 3.6 0.0 1.6 5.2 0.1 0.0 3.1 0.0 0.1 104.4 1.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.5 0.4 6.6 1.6 0.0 0.0 10.9 0.1 0.7 0.7 6.8 0.0 1.0 0.2 0.2 0.0 0.1 0.0 0.7 6.4 7.2 18.3 7.1 5.1 4.5 5.9 5.3 6.0 4.8 5.3 4.9 0.7 3.2 5.0 5.2 3.7 1.8 3.3 22.9 1.2 4.6 24.2 15.2 0.6 37.1 34.8 82.8 0.0 7.7 3.3 24.2 1.9 19.0 1.2 15.3 4.3 3.8 55.3 1.3 0.5 1.5 4.9 1.3 54.6 28.9 9.5 0.9 0.4 0.3 1.6 0.0 0.4 53.5 34.6 0.9 0.6 1.6 0.3 1.5 0.0 3.7 0.5 1.2 12.3 0.0 1.5 2.4 77.0 0.0 3.7 1.7 298.9 0.4 144.8 22.0 0.0 1.1 3.1 3.2 4.0 86.9 15.3 37.4 2.5 0.2 69.6 21.0 DENND1C "FAM31C, FLJ22757" ENSG00000205744 "DENN domain containing 1C" Q8IV53 19 6467207-6482557 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.2;intestine: 14.4;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "B-cells: 27.5;dendritic cells: 30.1;granulocytes: 15.9;Hofbauer cells: 14.6;NK-cells: 35.0;T-cells: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 22.5;HEL: 15.1;HMC-1: 44.7;MOLT-4: 14.7;THP-1: 13.8;U-937: 31.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042758, HPA042839" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Centrosome" "HPA042758: AB_10962357, HPA042839: AB_10959898" "unprognostic (5.94e-2)" "unprognostic (1.41e-3)" "unprognostic (4.26e-2)" "unprognostic (1.93e-3)" "unprognostic (1.21e-1)" "unprognostic (1.72e-3)" "unprognostic (3.91e-2)" "prognostic favorable (1.23e-4)" "unprognostic (7.76e-3)" "unprognostic (4.45e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.95e-4)" "prognostic favorable (7.51e-14)" "unprognostic (1.37e-3)" "unprognostic (1.27e-1)" "unprognostic (4.53e-2)" "prognostic favorable (5.62e-4)" 2.2 1.0 1.4 21.4 1.3 21.2 1.0 1.5 1.7 0.9 1.5 3.0 4.9 0.9 0.0 1.9 1.3 2.8 1.1 1.4 1.5 1.6 2.1 5.8 32.1 2.4 1.8 0.3 1.3 0.1 0.8 1.8 2.2 1.6 1.2 0.0 3.0 0.5 0.8 1.4 14.4 1.2 1.8 35.1 5.2 0.4 2.8 20.5 1.7 0.3 14.9 3.0 1.3 2.6 0.2 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.5 0.0 22.5 0.1 0.0 0.1 0.2 0.1 0.3 0.0 0.0 0.0 15.1 0.0 1.6 0.0 7.5 44.7 0.0 0.0 0.1 0.0 0.0 0.0 7.4 0.3 9.4 0.1 0.0 14.7 11.5 0.0 0.5 0.0 1.7 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 13.8 0.1 0.0 0.0 0.0 0.0 0.4 2.0 10.6 0.1 31.3 0.0 18.3 19.9 32.8 40.1 32.4 35.0 23.8 28.6 35.0 19.5 18.7 35.7 32.1 27.8 23.8 35.0 11.2 35.6 37.1 1.4 1.3 1.5 1.7 1.4 1.5 2.4 1.8 2.2 1.8 2.8 2.6 0.3 3.2 3.0 0.0 27.5 0.4 0.1 0.0 1.2 0.0 0.6 0.6 1.3 2.8 0.0 1.8 0.0 0.2 30.1 0.5 1.9 0.4 0.7 1.5 0.2 0.4 0.0 5.7 0.4 0.0 0.2 0.7 1.5 0.3 15.9 0.5 1.1 0.7 14.6 0.0 0.5 0.9 0.0 11.6 9.2 0.6 0.0 13.8 3.6 2.8 10.9 0.0 35.0 0.0 0.5 0.3 0.4 0.0 13.5 0.2 2.9 6.2 1.6 0.0 0.0 0.0 0.3 0.3 1.2 1.6 0.1 0.3 34.5 0.7 1.0 0.1 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 143.2;Inhibitory neurons: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 17.3;HeLa: 21.8;U-698: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027530: AB_2672320, HPA049101: AB_2680630" "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.2 3.4 4.3 1.9 5.5 12.0 5.9 20.5 6.2 4.5 3.2 9.0 1.6 5.9 1.6 2.2 5.7 1.0 7.6 5.8 4.0 2.5 3.6 10.6 4.3 6.5 3.9 8.9 2.7 0.4 3.7 2.9 7.4 5.7 2.3 5.4 5.9 0.5 30.4 3.0 12.9 0.7 4.1 11.4 25.2 9.6 4.4 1.0 8.3 0.9 4.5 5.3 2.6 8.8 1.7 8.5 2.1 1.5 1.5 1.4 3.0 2.4 1.0 0.6 0.5 9.7 1.9 10.3 1.1 2.4 4.5 2.0 2.4 1.0 3.2 17.3 11.3 4.7 21.8 5.8 0.9 11.7 7.2 2.3 2.2 1.1 2.1 1.8 0.8 2.1 7.8 1.8 1.6 3.1 9.2 3.3 1.6 2.8 6.9 14.5 5.7 1.6 0.9 3.3 2.1 2.2 1.4 2.3 1.0 1.8 0.6 5.2 1.0 1.2 3.0 1.2 1.7 7.1 6.2 22.7 0.8 5.6 0.6 1.7 1.6 5.6 2.1 0.6 1.1 4.8 0.5 1.5 0.4 5.0 1.7 2.4 1.2 0.6 1.0 0.4 0.2 1.7 4.3 5.5 20.5 6.2 5.8 4.0 6.5 3.9 7.4 4.1 4.4 8.8 18.9 32.1 46.2 27.1 61.1 8.9 6.4 5.6 4.6 33.8 19.6 11.6 21.0 0.0 13.8 0.0 62.6 14.6 62.0 40.6 0.0 3.6 14.9 23.4 12.5 19.1 2.4 5.0 11.1 4.4 1.2 9.7 143.2 38.1 5.7 13.1 4.6 7.0 6.8 8.4 137.9 32.8 8.2 10.4 13.8 38.7 6.5 28.7 8.8 11.2 17.5 13.9 49.4 43.2 81.5 26.0 13.5 4.5 34.7 17.6 29.6 2.6 4.8 44.3 19.7 49.4 21.2 14.4 29.3 4.5 3.7 2.5 32.5 7.6 20.1 9.9 DISP1 "DISPA, DKFZP434I0428, MGC13130, MGC16796" ENSG00000154309 "Dispatched RND transporter family member 1" Q96F81 1 222815022-223005995 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.7;Gastric mucus-secreting cells: 48.4;Inhibitory neurons: 54.4;Microglial cells: 204.2;Oligodendrocyte precursor cells: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 15.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051411 Uncertain Approved "Nuclear bodies" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear bodies" "HPA051411: AB_2681475" "unprognostic (2.10e-2)" "unprognostic (3.31e-1)" "unprognostic (7.00e-2)" "unprognostic (7.81e-2)" "unprognostic (7.82e-2)" "unprognostic (2.88e-1)" "unprognostic (2.71e-1)" "unprognostic (1.27e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-1)" "prognostic favorable (5.00e-4)" "unprognostic (4.13e-1)" "prognostic favorable (3.86e-5)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "prognostic favorable (4.16e-4)" "unprognostic (9.69e-3)" 6.8 5.7 1.7 1.5 2.0 0.2 3.0 4.0 2.5 3.2 3.7 9.0 2.6 4.3 2.0 1.9 2.4 4.6 3.9 1.6 1.9 5.2 2.7 9.2 1.1 1.2 0.9 4.5 2.4 5.1 2.5 4.6 1.1 2.4 2.1 1.3 1.9 2.0 4.1 3.3 3.7 4.2 0.7 2.5 5.3 6.5 1.5 1.4 5.2 3.1 1.4 5.4 2.5 2.6 0.9 2.2 5.6 3.8 10.1 6.1 2.4 3.2 2.7 1.1 1.1 2.6 1.6 0.1 4.2 1.5 2.2 0.6 1.6 1.3 1.6 8.1 2.4 1.1 6.3 1.2 4.4 0.2 1.1 4.8 1.9 2.3 0.9 5.8 2.3 1.2 0.0 0.1 3.9 1.5 1.4 0.3 4.0 6.1 1.3 1.7 15.1 0.2 6.8 0.8 1.6 2.5 1.8 0.7 2.3 2.7 2.7 1.4 4.2 2.3 1.5 3.9 3.6 1.2 0.5 0.3 3.2 0.8 5.1 0.3 0.2 0.0 0.7 0.4 1.6 0.5 0.6 0.7 0.6 0.9 0.6 0.5 0.1 1.0 0.2 0.3 0.5 0.4 1.7 2.0 4.0 2.5 1.6 1.9 1.2 0.9 1.1 0.7 1.5 2.6 4.6 6.4 1.7 42.7 3.6 0.5 0.6 1.2 5.7 2.7 3.4 1.5 7.8 7.2 3.3 11.0 0.0 1.4 2.1 1.0 0.0 1.9 2.1 1.9 3.4 4.9 0.0 0.0 47.7 2.8 1.8 5.6 48.4 4.1 0.0 15.8 6.8 3.3 5.9 0.0 54.4 2.6 4.1 1.6 0.9 3.7 1.5 4.1 0.0 204.2 1.4 0.9 5.2 199.6 15.4 1.3 3.1 3.4 0.7 0.7 6.4 5.8 2.7 2.3 0.0 4.0 3.7 2.1 2.3 5.4 1.1 0.8 1.7 2.8 1.6 0.3 DLG5 "KIAA0583, P-dlg" ENSG00000151208 "Discs large MAGUK scaffold protein 5" Q8TDM6 10 77790791-77926755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 112.5;Glandular and luminal cells: 139.6;Horizontal cells: 186.7;Syncytiotrophoblasts: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "PC-3: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001746 Supported "Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA001746: AB_2666418" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (6.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (5.38e-4)" "unprognostic (8.48e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.60e-1)" "unprognostic (8.00e-2)" "unprognostic (3.06e-1)" "unprognostic (5.13e-1)" "unprognostic (6.00e-2)" "unprognostic (2.74e-2)" 11.9 51.8 8.3 0.5 8.1 0.2 19.4 7.7 8.5 24.4 9.4 28.6 0.3 25.1 16.3 19.7 17.7 1.1 7.4 8.1 8.6 8.8 4.6 8.6 0.4 17.2 9.6 19.5 11.1 6.1 33.9 2.4 10.2 31.2 1.7 4.2 16.8 2.9 26.3 36.3 12.5 2.2 10.1 4.1 16.4 6.2 8.6 1.2 22.3 0.9 1.4 20.3 22.2 10.3 5.7 0.1 4.5 4.9 6.8 2.9 2.9 6.3 3.7 1.1 1.1 0.0 3.8 0.0 6.0 3.2 1.9 6.0 2.3 3.4 4.2 2.0 7.5 1.1 0.0 7.0 6.5 0.4 1.5 3.3 8.1 0.2 9.8 8.2 0.4 0.1 3.0 0.0 3.4 2.0 0.6 1.8 4.3 7.0 20.0 4.1 1.4 0.3 4.8 0.0 1.5 4.2 2.7 5.7 2.2 6.1 2.3 1.1 1.9 1.2 9.2 1.2 5.7 0.0 0.7 0.5 1.2 1.2 0.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 8.1 7.7 8.5 8.1 8.6 17.2 9.6 10.2 10.1 8.6 10.3 5.2 6.4 5.4 21.2 0.5 29.6 24.2 20.2 12.0 18.3 41.9 28.3 2.8 12.8 13.6 20.2 16.7 112.5 12.1 12.2 0.0 6.7 16.4 55.6 41.7 4.9 2.4 0.0 24.0 5.9 23.6 12.5 8.2 139.6 1.3 49.4 3.3 3.3 13.1 186.7 28.3 10.4 8.2 0.0 3.9 10.2 18.6 1.8 8.8 10.3 0.8 46.4 9.2 19.1 13.6 12.4 7.6 18.4 6.8 25.4 15.2 2.1 34.6 15.3 26.3 24.2 15.1 1.6 7.6 10.8 24.2 171.6 5.5 10.4 10.1 23.5 DLGAP4 "DAP4, KIAA0964, SAPAP4" ENSG00000080845 "DLG associated protein 4" Q9Y2H0 20 36306336-36528637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 213.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054105, HPA056378" Approved Approved "Nucleoplasm,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA054105: AB_2682381, HPA056378: " "unprognostic (1.11e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-2)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (3.73e-6)" "unprognostic (1.23e-1)" "prognostic favorable (9.88e-5)" "unprognostic (1.28e-1)" "unprognostic (2.18e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" 55.4 47.5 39.0 23.5 31.4 7.5 40.3 2.8 45.9 51.7 2.6 71.4 21.2 64.5 12.5 31.7 45.2 26.4 58.4 39.3 12.3 34.3 37.3 60.5 16.6 5.4 18.1 48.4 47.8 13.8 36.4 26.5 10.5 44.7 15.0 25.4 37.8 30.6 130.8 86.8 37.1 42.5 2.8 32.9 36.5 29.3 29.1 14.7 43.3 45.9 14.8 56.2 46.6 20.6 49.9 44.2 53.0 44.1 49.0 79.9 53.2 73.2 66.5 70.0 48.2 67.4 30.9 14.0 38.5 103.3 61.9 46.7 14.3 75.1 51.8 22.5 5.2 31.8 22.7 46.2 70.9 12.9 26.5 52.9 57.0 83.1 57.6 54.2 69.7 19.5 22.5 37.2 53.6 37.0 26.3 49.0 23.2 36.2 93.4 26.1 14.0 19.4 33.0 24.3 34.8 47.9 48.0 96.0 60.0 53.7 55.3 22.3 71.2 212.1 64.6 92.6 40.9 12.7 9.8 15.1 84.9 16.2 85.4 2.7 16.5 26.9 15.0 17.3 11.9 19.5 13.5 10.7 14.5 20.8 10.1 8.1 23.6 9.6 17.9 17.4 11.9 12.6 39.0 31.4 2.8 45.9 39.3 12.3 5.4 18.1 10.5 2.8 29.1 20.6 30.4 16.0 20.5 34.0 25.2 66.4 53.8 30.6 9.1 34.9 30.2 21.0 27.9 22.8 22.9 12.9 8.4 23.1 23.7 27.2 7.9 53.0 69.9 25.9 47.7 36.6 63.3 4.4 77.9 55.7 52.3 40.1 23.4 29.4 12.6 35.7 27.8 17.5 27.2 74.0 93.4 35.0 20.3 22.4 54.4 213.4 29.8 23.9 10.6 37.5 47.5 38.7 21.6 81.4 13.2 84.4 25.0 26.4 8.9 72.9 25.8 20.4 28.3 29.5 72.3 28.8 51.0 13.7 30.3 13.2 71.7 55.1 20.7 29.8 20.6 52.3 DMD "BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85" ENSG00000198947 Dystrophin P11532 X 31097677-33339609 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" Actin-binding "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 452.8;Excitatory neurons: 1275.8;Inhibitory neurons: 719.8;Oligodendrocyte precursor cells: 1161.6;Oligodendrocytes: 610.2;Rod photoreceptor cells: 375.9" "Cancer enhanced" "Detected in many" "testis cancer: 8.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 7 "B-cells: 1.1;granulocytes: 4.3" "Cell line enhanced" "Detected in many" "AF22: 27.9;Hep G2: 30.3;RH-30: 25.0;SuSa: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000119, HPA002725, HPA023885" Enhanced NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB000119: , HPA002725: AB_1078714, HPA023885: AB_1847931" "unprognostic (3.91e-3)" "unprognostic (2.29e-1)" "unprognostic (1.83e-2)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (7.58e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-4)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (5.84e-3)" "unprognostic (2.38e-1)" "unprognostic (1.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.82e-1)" "unprognostic (9.83e-2)" "unprognostic (1.51e-2)" 16.3 14.7 11.8 5.3 12.5 0.6 16.8 0.2 14.2 7.1 7.1 38.0 5.4 18.1 11.2 9.1 16.8 21.5 37.8 15.5 0.5 5.4 50.0 7.2 4.7 1.1 0.6 13.9 52.9 4.3 4.4 15.1 0.4 13.4 8.4 80.0 30.2 30.7 73.4 11.5 9.4 22.0 0.0 2.3 15.5 8.3 4.8 3.3 7.3 67.4 6.4 21.1 7.2 9.9 0.3 0.2 27.9 0.3 0.3 0.3 7.6 6.1 0.6 2.8 3.1 13.3 0.6 0.4 0.2 12.5 2.3 8.5 10.5 15.0 4.2 7.4 8.6 3.3 10.5 30.3 14.7 1.2 3.7 3.3 9.5 4.6 17.1 15.3 6.1 2.0 2.9 0.4 8.3 0.5 4.4 0.6 13.3 0.1 9.8 0.3 25.0 0.1 0.3 3.3 0.5 8.5 0.1 2.3 2.8 27.7 2.2 0.1 1.6 0.3 0.5 1.1 4.6 0.4 23.8 0.6 1.0 2.3 14.4 0.8 0.1 2.0 0.1 0.1 0.1 1.1 0.1 0.1 0.3 0.9 0.1 0.1 4.3 0.1 0.1 0.4 0.2 0.1 11.8 12.5 0.2 14.2 15.5 0.5 1.1 0.6 0.4 0.0 4.8 9.9 8.5 28.9 25.3 164.9 6.7 20.1 7.0 6.3 3.4 78.0 26.5 50.0 452.8 7.2 15.0 3.7 308.6 33.7 0.7 0.8 3.9 3.8 22.4 22.5 1.4 9.9 8.4 0.0 1275.8 12.3 9.5 26.1 3.6 5.6 1.3 37.9 6.1 49.8 4.2 11.8 719.8 1.3 6.1 4.8 5.4 20.5 89.2 3.5 19.6 94.6 6.7 54.9 0.0 1161.6 610.2 6.0 0.1 118.8 0.2 3.6 3.6 2.1 60.4 375.9 118.3 95.2 50.3 4.0 8.8 1.8 11.5 5.1 1.0 33.1 4.2 4.8 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNAAF3 "C19orf51, CILD2, FLJ36139, FLJ40069, PCD, PF22" ENSG00000167646 "Dynein axonemal assembly factor 3" Q8N9W5 19 55158661-55166722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 40.8;testis: 65.4" "Group enriched" "Detected in many" 5 "Early spermatids: 395.2;Late spermatids: 722.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 26.2;HEL: 31.6;K-562: 25.3;U-937: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056220 Approved "Nuclear bodies,Mitochondria" No No "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Nuclear bodies" "HPA056220: AB_2683071" "unprognostic (1.71e-2)" "unprognostic (2.67e-2)" "unprognostic (6.10e-2)" "unprognostic (9.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (1.82e-1)" "unprognostic (5.36e-2)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (8.03e-2)" 0.4 1.8 1.5 0.0 1.2 0.0 0.6 0.9 0.7 2.5 6.1 0.3 0.1 0.9 3.4 0.6 40.8 0.6 5.0 1.5 2.3 2.7 0.6 4.3 0.1 4.0 8.2 0.2 1.6 3.5 0.7 0.1 4.7 0.3 0.1 0.4 0.4 0.9 0.1 0.9 0.3 0.2 3.1 0.3 0.3 65.4 1.5 0.5 2.3 0.0 0.1 0.1 0.4 2.1 8.8 6.6 0.6 6.7 0.1 0.0 0.6 0.1 0.2 1.0 0.7 0.3 4.0 10.5 2.5 0.3 1.9 10.1 1.5 3.0 0.4 0.0 26.2 31.6 0.5 0.5 0.2 13.6 3.1 0.2 4.0 1.7 2.2 0.9 0.5 4.7 25.3 13.9 0.4 5.9 0.4 0.3 0.5 9.5 15.0 16.5 1.0 3.2 5.4 0.2 0.8 2.6 1.1 1.1 1.6 0.2 8.3 0.4 1.0 0.8 3.9 4.0 0.2 0.4 2.5 0.6 4.9 18.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.2 0.9 0.7 1.5 2.3 4.0 8.2 4.7 3.1 1.5 2.1 0.2 0.0 0.5 0.0 0.0 3.2 0.0 4.7 4.6 0.0 1.1 0.6 3.0 1.5 7.5 7.3 0.0 0.0 0.0 0.3 7.9 2.7 395.2 55.8 0.5 0.6 0.0 0.0 0.5 1.0 0.1 1.2 0.0 1.3 0.0 1.9 0.7 0.4 0.2 0.0 0.5 0.5 12.2 0.0 0.4 722.0 4.4 4.2 0.0 0.0 0.0 2.1 0.0 0.5 0.1 0.2 0.1 3.0 0.0 0.1 0.0 5.1 75.2 0.0 0.0 0.0 2.3 104.8 18.6 0.3 1.3 0.0 0.1 1.1 0.4 0.2 DNAH5 "CILD3, Dnahc5, HL1, KTGNR, PCD" ENSG00000039139 "Dynein axonemal heavy chain 5" Q8TE73 5 13690328-14011818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 14.0" "Cell type enhanced" "Detected in many" "Club cells: 61.7;Endometrial ciliated cells: 190.3;Respiratory ciliated cells: 258.7" "Cancer enhanced" "Detected in many" "prostate cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;LHCN-M2: 1.1;PC-3: 2.7;RPTEC TERT1: 1.3;TIME: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA037469, HPA037470" Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA037469: AB_10672791, HPA037470: AB_10672348" "unprognostic (3.85e-1)" "unprognostic (8.17e-2)" "unprognostic (5.94e-2)" "unprognostic (1.12e-1)" "unprognostic (4.58e-3)" "unprognostic (6.23e-2)" "unprognostic (3.33e-3)" "unprognostic (2.86e-2)" "unprognostic (9.94e-2)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (9.99e-2)" "unprognostic (9.97e-3)" "unprognostic (8.87e-2)" "unprognostic (8.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.65e-1)" 0.0 0.1 0.9 0.0 1.1 0.0 1.5 0.5 0.3 0.3 14.0 0.1 0.0 0.1 0.1 0.0 3.8 0.1 0.0 1.0 1.7 0.8 1.0 1.7 0.0 4.2 6.7 0.0 0.9 0.0 2.0 0.0 4.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.4 0.3 1.8 0.0 1.1 0.0 0.0 0.8 0.0 1.4 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.0 0.5 0.0 0.5 0.2 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.3 0.4 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.5 0.3 1.0 1.7 4.2 6.7 4.0 2.1 1.8 1.4 0.3 3.2 24.4 7.2 0.2 0.0 1.7 5.6 0.0 0.0 11.7 7.0 1.5 14.3 61.7 5.5 0.0 0.0 0.1 0.0 0.0 6.7 7.3 190.3 1.9 1.2 1.8 0.0 12.9 3.6 0.2 1.8 0.0 12.4 2.5 0.0 0.0 10.9 0.0 0.0 7.8 0.0 6.1 0.0 0.0 5.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 4.0 0.4 2.6 0.0 0.0 0.1 14.8 0.0 4.3 258.7 0.0 0.0 1.6 2.6 2.6 3.6 0.0 0.0 0.0 0.4 0.1 0.0 3.8 DNAI1 "CILD1, DIC1, PCD" ENSG00000122735 "Dynein axonemal intermediate chain 1" Q9UI46 9 34457414-34520988 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.9;choroid plexus: 28.3;fallopian tube: 33.9;pituitary gland: 9.5;testis: 33.5" "Cell type enhanced" "Detected in some" "Early spermatids: 29.6;Endometrial ciliated cells: 48.8;Late spermatids: 35.0;Respiratory ciliated cells: 132.2;Spermatocytes: 56.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;HDLM-2: 1.4;SK-BR-3: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021649, HPA021843" Enhanced NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA021649: AB_1847913, HPA021843: AB_1847914" "unprognostic (9.61e-2)" "unprognostic (5.16e-2)" "unprognostic (4.59e-2)" "unprognostic (1.44e-3)" "unprognostic (3.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (6.39e-2)" "unprognostic (4.38e-1)" "unprognostic (1.51e-1)" "unprognostic (8.16e-3)" "unprognostic (8.14e-2)" "unprognostic (2.74e-2)" "unprognostic (3.77e-2)" "unprognostic (2.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" 0.0 0.0 2.7 0.0 3.2 0.0 0.5 2.3 2.5 2.2 28.3 0.0 0.0 0.9 0.2 0.0 33.9 0.1 0.1 2.8 3.1 1.3 0.1 4.5 0.0 7.3 9.9 0.1 0.9 1.2 9.5 0.0 4.8 0.2 0.0 2.7 0.0 0.1 0.1 0.0 0.0 0.0 5.5 0.0 0.2 33.5 3.2 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.6 0.2 0.0 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.0 0.2 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.2 2.3 2.5 2.8 3.1 7.3 9.9 4.8 5.5 3.2 2.4 0.0 0.0 0.5 3.9 0.1 0.0 0.0 5.0 0.0 0.0 0.5 0.3 0.4 0.0 11.0 0.0 4.2 0.2 0.0 0.0 1.9 0.0 29.6 48.8 0.5 0.2 0.0 0.0 9.4 0.0 0.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 2.0 0.0 0.0 35.0 0.3 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.1 0.0 0.4 132.2 1.3 0.0 0.0 1.4 56.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DNAJB12 "DJ10, FLJ20027" ENSG00000148719 "DnaJ heat shock protein family (Hsp40) member B12" Q9NXW2 10 72332830-72355149 "Predicted membrane proteins, Transporters" "Host-virus interaction" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 235.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010642, HPA072702" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "Nuclear membrane" "HPA010642: AB_1078692, HPA072702: " "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (6.01e-3)" "unprognostic (2.68e-1)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.73e-2)" "unprognostic (5.60e-2)" "unprognostic (8.85e-3)" "unprognostic (1.95e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (4.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.87e-1)" 24.1 29.8 18.3 18.1 19.5 27.6 24.5 20.0 20.4 21.6 19.5 23.3 21.4 24.0 23.4 23.2 20.8 17.5 26.8 19.0 18.1 23.9 28.0 21.1 16.4 20.0 18.8 22.6 26.9 32.9 23.7 20.3 19.1 23.4 14.7 16.6 28.4 17.7 37.5 28.5 20.7 19.0 18.4 24.8 23.9 21.4 18.9 17.3 23.5 23.5 16.0 21.6 20.6 20.0 37.4 38.3 23.4 39.3 30.5 31.1 29.6 36.6 63.8 49.5 45.9 44.7 64.3 27.2 28.8 45.1 31.3 61.4 22.2 33.0 26.9 29.9 29.4 14.7 23.0 29.6 68.5 30.1 54.2 39.6 67.6 44.1 55.8 45.0 35.1 25.6 23.2 40.2 43.3 36.7 26.0 26.3 10.8 29.1 11.1 23.4 17.8 18.9 37.7 21.7 16.1 23.0 20.0 74.0 36.8 12.9 28.2 34.2 39.1 24.6 33.4 28.0 46.7 33.8 27.3 16.0 40.6 32.6 17.1 18.7 29.2 18.7 12.8 31.5 11.4 11.5 12.5 9.6 24.6 11.1 10.3 10.2 36.6 13.9 28.9 16.4 13.8 17.5 18.3 19.5 20.0 20.4 19.0 18.1 20.0 18.8 19.1 18.4 18.9 20.0 30.3 28.9 29.3 10.1 30.1 13.4 30.6 38.6 25.6 33.3 36.1 29.6 23.3 50.1 44.3 23.9 22.9 41.1 37.7 38.1 11.7 34.2 122.2 25.1 26.1 25.3 29.4 31.2 12.7 64.3 41.1 28.6 23.4 29.3 40.0 26.4 21.0 29.6 38.1 30.3 13.0 28.8 12.2 36.0 16.0 235.7 36.4 37.6 10.6 7.5 39.6 33.6 35.0 12.1 15.2 34.9 38.1 35.0 34.2 27.4 62.2 34.4 26.8 35.6 52.6 27.4 34.4 32.4 10.9 28.1 15.5 68.0 22.8 37.0 25.9 35.2 DOCK9 "KIAA1058, ZIZ1" ENSG00000088387 "Dedicator of cytokinesis 9" Q9BZ29 13 98793429-99086625 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 216.7" "Cell type enhanced" "Detected in many" "Adipocytes: 158.7;Excitatory neurons: 150.6;Inhibitory neurons: 202.2;Microglial cells: 148.0;Oligodendrocyte precursor cells: 238.8;Oligodendrocytes: 402.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 2.0;MAIT T-cell: 4.8;memory CD4 T-cell: 5.2;memory CD8 T-cell: 2.1;naive CD4 T-cell: 6.0;naive CD8 T-cell: 4.0;NK-cell: 7.3;T-reg: 2.4" "Group enriched" "Detected in many" 11 "NK-cells: 7.3;T-cells: 6.0" "Cell line enhanced" "Detected in many" "BEWO: 200.8;hTERT-HME1: 435.4;HUVEC TERT2: 180.9;TIME: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034061, CAB034065, HPA043940" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB034061: AB_2277513, CAB034065: AB_2094798, HPA043940: AB_2678741" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (8.76e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (1.48e-1)" "unprognostic (3.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.47e-1)" "unprognostic (1.16e-1)" "unprognostic (6.38e-3)" "unprognostic (2.79e-1)" "unprognostic (7.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.36e-2)" "unprognostic (3.31e-2)" 83.2 22.4 82.6 21.4 137.2 6.0 71.1 96.6 91.0 42.9 30.8 44.4 15.7 31.3 35.5 93.1 30.3 36.6 58.9 72.8 93.8 21.9 15.8 93.0 33.8 116.6 112.1 27.4 19.9 41.8 21.1 98.2 123.4 23.0 20.8 39.5 51.2 21.7 25.9 76.9 35.2 36.9 86.6 16.8 24.7 16.2 110.4 47.8 62.6 64.3 40.4 29.0 49.6 216.7 61.6 19.4 10.6 14.2 10.6 8.3 200.8 17.2 14.2 12.1 10.7 127.4 47.7 51.3 39.8 16.6 21.8 59.5 27.4 54.3 21.8 52.2 15.2 0.0 37.6 2.1 14.0 0.1 2.9 9.0 37.2 12.4 435.4 27.9 180.9 33.0 10.6 11.6 52.1 20.2 35.5 0.3 4.9 84.6 14.2 2.1 39.3 2.7 38.3 50.8 22.4 24.3 26.4 63.4 15.7 85.9 16.9 0.4 179.7 9.7 11.4 6.5 28.5 17.6 14.8 8.6 15.6 0.0 16.0 0.0 0.0 0.0 2.0 0.0 4.8 0.6 5.2 2.1 0.0 0.2 6.0 4.0 0.1 7.3 0.0 0.0 2.4 1.5 82.6 137.2 96.6 91.0 72.8 93.8 116.6 112.1 123.4 86.6 110.4 216.7 158.7 16.0 39.5 37.5 3.4 15.3 7.1 14.7 10.2 37.9 15.4 6.5 9.4 11.5 12.5 9.2 50.1 35.6 7.0 11.9 1.9 5.4 1.7 10.5 5.3 90.2 6.7 3.6 150.6 6.6 8.3 17.2 2.6 21.4 2.5 18.0 47.8 8.4 5.0 25.2 202.2 6.0 10.2 1.9 7.4 3.3 7.8 1.7 1.8 148.0 0.4 12.9 4.1 238.8 402.2 14.7 5.6 14.7 2.8 10.1 10.6 3.8 7.1 23.9 0.0 122.6 12.4 7.2 5.4 25.6 32.0 17.2 11.0 2.4 5.9 10.5 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 DPH6 "ATPBD4, MGC14798" ENSG00000134146 "Diphthamine biosynthesis 6" Q7L8W6 15 35217345-35546193 "Enzymes, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 91.7;Oligodendrocytes: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042976, HPA055496" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042976: AB_10964890, HPA055496: AB_2682835" "unprognostic (9.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-1)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.45e-2)" "unprognostic (1.60e-1)" "unprognostic (9.94e-2)" "unprognostic (1.76e-1)" "unprognostic (1.49e-3)" "unprognostic (7.92e-3)" "unprognostic (1.13e-1)" "unprognostic (4.65e-6)" "unprognostic (9.70e-2)" "unprognostic (5.61e-2)" "unprognostic (2.18e-2)" "unprognostic (7.44e-2)" 8.6 7.5 3.7 4.9 4.7 5.4 10.8 4.6 5.0 6.8 3.6 6.7 6.1 7.9 10.7 9.6 8.1 6.0 10.2 3.6 4.7 10.4 8.1 5.3 5.3 4.6 4.4 9.7 14.3 8.7 5.9 8.1 4.8 5.8 7.0 8.9 6.7 6.1 10.8 9.7 6.6 6.4 4.3 6.3 6.8 5.9 3.9 7.0 10.8 6.9 7.4 8.0 7.1 5.7 16.9 8.9 14.7 12.5 2.6 11.7 14.3 6.2 10.8 14.7 7.6 11.9 15.5 5.2 14.8 5.7 17.9 19.0 17.2 17.9 17.5 4.1 10.7 19.6 9.9 18.9 15.3 10.6 12.1 9.9 22.2 5.9 28.5 9.0 14.4 11.0 21.8 20.6 13.6 6.6 13.0 9.8 13.0 25.4 8.1 16.0 13.7 7.2 12.9 21.0 10.7 10.4 11.6 12.8 10.7 8.5 44.6 14.4 4.4 14.2 13.8 14.4 10.0 18.2 31.3 13.4 12.3 17.7 13.9 0.0 6.7 0.3 6.0 6.7 7.7 8.9 8.1 8.4 6.7 6.3 10.3 9.3 0.3 14.7 6.2 5.8 5.8 4.5 3.7 4.7 4.6 5.0 3.6 4.7 4.6 4.4 4.8 4.3 3.9 5.7 15.9 16.0 7.5 91.7 18.7 31.0 20.0 19.8 24.5 29.2 12.0 16.6 15.8 18.6 17.2 9.2 39.6 26.7 9.3 7.5 13.7 16.3 2.2 10.7 13.7 10.0 5.4 16.8 28.0 24.1 23.5 12.0 21.4 13.3 3.8 21.1 5.7 7.4 17.5 18.5 47.0 7.4 14.2 10.3 12.9 3.3 14.0 9.8 16.0 44.0 14.3 15.0 11.3 71.9 101.5 18.7 7.1 6.8 6.9 8.9 13.4 19.9 7.6 24.2 0.0 18.9 14.0 9.8 14.0 21.2 23.2 22.6 9.9 21.9 10.5 13.4 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DST "BP240, BPA, BPAG1, CATX-15, FLJ13425, FLJ21489, FLJ30627, FLJ32235, KIAA0728, MACF2" ENSG00000151914 Dystonin Q03001 6 56457987-56954830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Cancer-related genes, Epidermolysis bullosa, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2368.6;Basal prostatic cells: 1651.4;Basal squamous epithelial cells: 3008.4;Cone photoreceptor cells: 1401.1;Oligodendrocytes: 1410.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 488.1;hTERT-HME1: 371.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030200 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA 16000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Microtubules" Cytosol "HPA030200: AB_10601901" "unprognostic (4.87e-3)" "unprognostic (1.29e-1)" "unprognostic (3.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.25e-2)" "unprognostic (3.60e-2)" "unprognostic (5.78e-2)" "unprognostic (2.35e-2)" "unprognostic (1.09e-1)" "unprognostic (2.75e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (4.39e-2)" "unprognostic (5.13e-3)" "unprognostic (1.46e-1)" "unprognostic (2.66e-1)" "unprognostic (7.62e-2)" 60.9 86.2 206.5 16.2 275.8 3.3 117.3 240.6 221.9 158.8 143.3 173.2 25.4 167.1 38.2 66.1 103.9 32.6 166.0 194.6 230.7 52.2 80.8 108.0 11.3 258.1 250.4 78.2 39.8 36.7 78.8 28.7 263.4 84.5 32.4 87.4 100.3 48.7 143.1 166.2 64.2 106.0 209.1 36.7 68.9 28.4 243.3 31.4 29.8 104.1 15.2 90.4 113.2 325.4 62.4 26.6 41.2 20.8 79.5 103.5 24.6 82.2 89.7 37.8 42.1 17.1 15.5 10.4 32.2 220.7 35.6 46.7 34.4 161.2 73.0 52.3 45.2 17.8 49.5 31.4 65.9 15.0 0.4 58.3 488.1 92.5 371.6 69.1 73.3 9.5 12.6 38.2 113.9 20.2 5.1 6.8 27.7 35.6 21.9 0.1 28.8 16.5 118.8 83.0 47.2 37.8 32.7 11.7 64.1 67.7 18.6 27.2 176.5 77.3 55.9 37.0 68.9 39.6 28.6 5.0 55.8 8.8 40.3 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 0.3 1.3 0.0 0.1 206.5 275.8 240.6 221.9 194.6 230.7 258.1 250.4 263.4 209.1 243.3 325.4 193.2 336.5 11.8 1048.7 5.6 2368.6 1651.4 250.1 3008.4 673.1 81.0 301.5 862.8 77.2 161.7 55.2 1401.1 61.5 7.8 357.8 7.9 204.3 53.6 133.8 218.4 122.7 44.9 12.4 550.4 66.3 11.6 212.5 71.9 166.8 17.1 478.7 60.7 80.3 21.8 307.9 591.7 100.3 118.0 74.2 124.6 15.5 133.3 56.6 215.3 215.5 46.6 200.8 2.1 630.3 1410.3 194.1 283.0 152.4 27.2 229.8 124.2 10.3 52.0 122.6 65.7 381.8 196.6 20.0 13.7 298.2 857.2 26.5 19.7 30.5 48.1 142.8 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143169-96145440 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.5" "Cell type enhanced" "Detected in many" "dendritic cells: 919.7;Glandular and luminal cells: 321.1;Langerhans cells: 924.0;Macrophages: 353.9;T-cells: 764.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 55.0" "Immune cell enhanced" "Detected in all" "gdT-cell: 199.3" "Group enriched" "Detected in all" 10 "NK-cells: 148.1;T-cells: 199.3" "Cell line enhanced" "Detected in many" "Daudi: 30.4;HeLa: 29.7;JURKAT: 27.6;Karpas-707: 33.8;NB-4: 29.1;RT4: 34.2;SCLC-21H: 29.6;U-698: 43.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 17.0 6.0 7.6 18.6 11.6 129.5 5.5 7.5 55.0 8.1 9.2 4.5 1.6 7.0 7.7 6.8 7.6 12.5 19.5 13.4 6.2 12.7 7.5 18.2 47.1 8.0 6.3 7.8 2.3 1.7 35.1 1.3 6.7 17.6 2.0 0.4 3.9 61.5 2.8 26.0 11.8 3.4 6.7 42.0 7.4 3.6 6.9 47.3 6.7 3.7 24.6 39.5 9.0 9.3 3.2 0.0 0.2 0.2 0.4 0.5 4.4 3.7 0.0 5.3 5.1 8.9 0.6 30.4 10.6 4.1 0.0 2.2 7.5 0.0 1.0 0.5 0.0 0.7 29.7 0.0 1.9 12.8 2.6 0.9 2.0 0.9 0.0 0.1 0.0 27.6 0.0 33.8 0.2 5.2 25.5 29.1 6.5 0.8 10.6 0.0 0.4 24.3 0.2 34.2 29.6 1.5 1.4 0.3 5.6 0.0 2.0 14.4 0.1 0.0 7.9 0.0 1.7 2.3 3.9 43.2 0.0 13.9 0.3 2.3 4.3 1.0 199.3 10.5 95.4 17.5 46.7 176.2 10.7 13.9 32.0 99.3 6.1 148.1 9.1 3.0 16.1 40.5 7.6 11.6 7.5 55.0 13.4 6.2 8.0 6.3 6.7 6.7 6.9 9.3 50.8 0.0 7.7 0.7 303.7 96.7 155.0 31.3 70.6 27.8 65.8 72.0 37.8 2.8 12.0 9.2 22.9 0.9 919.7 20.4 1.9 0.9 0.9 115.6 62.7 28.7 87.8 50.5 5.2 1.4 1.7 22.8 86.6 321.1 104.3 7.4 12.8 3.9 80.2 0.0 1.4 37.5 8.2 40.4 924.0 1.4 1.8 353.9 144.1 1.9 3.4 1.5 90.6 1.0 0.5 1.0 2.5 1.9 268.5 70.4 1.6 1.4 2.7 3.6 0.0 14.7 26.6 0.6 4.8 50.4 109.7 1.6 764.7 3.0 51.6 41.1 DZIP1 "DZIP, KIAA0996" ENSG00000134874 "DAZ interacting zinc finger protein 1" Q86YF9 13 95578202-95644706 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 384.1;Late spermatids: 774.5;Spermatocytes: 222.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054891, HPA057272" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA054891: AB_2682631, HPA057272: AB_2683390" "unprognostic (6.74e-3)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (4.64e-3)" "unprognostic (4.82e-2)" "unprognostic (5.52e-3)" "unprognostic (6.34e-2)" "unprognostic (2.49e-1)" "unprognostic (3.34e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-3)" "unprognostic (1.48e-1)" "unprognostic (3.64e-2)" "unprognostic (3.89e-3)" 5.0 3.4 8.6 2.5 8.5 0.1 4.4 6.9 9.4 12.4 5.7 10.7 1.0 12.6 7.2 3.2 12.4 5.1 4.3 7.7 8.7 11.4 1.1 4.6 2.2 7.0 8.1 16.3 9.9 0.4 10.3 2.5 6.1 6.4 1.8 4.0 2.3 6.2 1.3 1.6 4.0 6.1 5.6 1.5 4.7 14.8 11.5 0.8 2.4 2.1 1.7 7.9 7.1 7.1 1.1 4.2 17.5 15.5 14.5 16.2 3.6 11.0 13.2 12.7 15.2 0.2 0.0 0.0 2.5 9.4 5.5 0.0 11.7 3.8 14.8 1.1 9.6 15.6 4.4 11.0 9.2 0.1 0.0 11.7 0.4 4.2 5.8 23.1 9.1 1.1 0.0 0.1 11.4 0.0 0.0 0.0 8.6 0.0 0.4 0.0 10.1 0.0 15.4 1.8 4.2 9.9 8.3 0.0 0.6 22.4 0.0 7.3 1.3 12.3 5.3 1.8 8.8 0.0 0.0 0.0 3.5 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 6.9 9.4 7.7 8.7 7.0 8.1 6.1 5.6 11.5 7.1 2.4 0.0 0.0 63.6 0.0 0.6 1.1 3.1 4.6 18.7 0.6 3.4 3.5 2.8 3.9 1.8 4.2 4.5 0.0 0.0 7.9 20.8 384.1 37.2 34.1 2.5 0.0 0.0 86.8 0.2 2.6 19.0 0.5 2.7 0.0 3.1 2.9 0.4 0.7 6.7 95.7 0.0 4.1 0.3 1.5 774.5 38.8 1.2 3.6 19.7 2.0 8.3 0.0 106.6 5.1 0.6 0.0 43.6 0.0 0.8 0.0 24.4 19.4 1.5 19.7 18.2 15.8 222.8 12.6 1.2 1.0 1.8 0.5 20.8 0.0 0.3 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 EBF4 "COE4, KIAA1442, O/E-4, RP5-860F19.3" ENSG00000088881 "EBF family member 4" Q9BQW3 20 2692874-2760108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 18.9;Cholangiocytes: 21.5;Endometrial stromal cells: 18.6;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 7.9;HEK 293: 8.4;SH-SY5Y: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (9.57e-2)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (7.79e-3)" "unprognostic (3.82e-1)" "prognostic favorable (2.47e-5)" "unprognostic (2.68e-2)" "unprognostic (5.58e-3)" "unprognostic (1.87e-3)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.87e-3)" 2.6 3.5 12.1 2.7 13.5 0.3 2.7 9.1 15.0 5.0 3.0 3.2 2.8 19.0 2.2 4.1 6.7 5.7 2.9 12.9 11.1 2.6 1.1 3.6 2.3 13.4 11.4 13.7 3.8 14.4 2.9 5.7 9.9 12.4 1.9 3.3 5.6 11.1 1.1 2.8 3.8 12.1 10.6 2.2 3.9 1.2 13.1 0.6 18.0 1.5 1.8 3.0 2.0 17.4 0.0 0.7 4.4 4.4 0.1 1.1 0.9 1.2 3.2 2.2 1.1 0.6 0.4 0.0 2.5 0.5 7.9 0.2 1.5 0.2 1.3 6.2 8.4 0.0 0.0 0.2 2.8 0.0 0.0 0.1 1.0 1.0 0.0 0.8 0.3 1.9 0.0 0.0 0.0 0.4 0.1 6.9 0.6 0.0 0.2 6.4 1.2 0.5 0.0 2.7 3.3 21.2 1.2 0.1 1.9 4.2 2.4 0.3 1.7 0.3 1.0 0.2 3.8 1.4 0.2 1.5 0.0 0.9 3.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.1 13.5 9.1 15.0 12.9 11.1 13.4 11.4 9.9 10.6 13.1 17.4 4.1 0.0 1.1 18.9 0.3 3.4 15.6 3.0 6.8 7.7 18.1 11.0 2.2 21.5 5.5 1.8 0.0 0.2 5.1 0.2 0.0 2.0 0.4 1.2 18.6 3.2 0.0 0.0 3.1 0.4 0.1 5.1 1.1 1.1 0.0 1.9 6.4 5.7 0.3 5.0 12.2 0.2 4.1 0.8 1.4 0.8 3.4 0.3 1.8 10.3 0.0 5.5 2.1 52.3 17.9 0.3 1.7 7.2 0.4 11.3 0.0 0.2 4.9 2.3 6.6 3.3 5.1 0.6 1.4 0.6 1.0 0.3 0.7 0.1 0.4 9.3 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Autism spectrum disorder, Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1638.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 130.8;Cardiomyocytes: 125.5;Horizontal cells: 269.2;Rod photoreceptor cells: 50.9;Skeletal myocytes: 49.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 347.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 240.0;MCF7: 405.9;SCLC-21H: 187.0;T-47d: 157.2;U-2 OS: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Nucleoli,Cytosol NA NA 55000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 37: Myocytes - Muscle contraction" Cytosol Nucleoli "CAB034019: AB_1562672, HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (1.40e-2)" "unprognostic (6.82e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (5.17e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.85e-1)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (8.29e-3)" "unprognostic (1.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" 0.9 32.7 59.3 1.4 81.3 0.0 1.7 17.1 347.2 2.8 0.0 5.1 0.7 0.3 1.1 9.7 0.4 2.4 358.0 73.4 97.3 1.3 3.0 0.8 0.6 95.0 2.9 0.5 6.5 16.2 111.5 0.0 76.3 9.6 0.4 37.2 19.5 0.8 1638.0 6.8 1.9 0.8 0.0 0.3 8.5 1.2 30.7 0.2 0.7 320.7 0.1 2.2 1.8 125.0 0.5 71.0 0.8 16.8 0.0 0.6 7.9 10.0 1.3 51.6 16.3 9.8 41.5 0.0 110.4 0.5 13.4 38.8 240.0 0.7 115.9 0.5 13.1 0.0 24.1 4.1 2.9 0.0 13.4 1.4 2.2 0.1 1.0 0.2 0.0 0.0 3.4 0.2 0.5 405.9 1.4 0.5 11.4 95.6 96.5 8.0 0.2 10.2 2.4 3.9 187.0 89.9 90.0 12.6 1.6 2.2 157.2 3.8 0.0 0.3 202.9 0.7 1.8 0.3 0.9 1.4 0.9 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 59.3 81.3 17.1 347.2 73.4 97.3 95.0 2.9 76.3 0.0 30.7 125.0 0.1 0.0 0.0 9.4 0.7 0.4 0.9 0.0 0.0 130.8 11.8 4.6 125.5 1.5 0.6 0.0 12.5 0.0 1.1 0.4 0.0 1.3 0.2 0.5 0.3 2.2 0.0 0.0 35.5 0.2 0.2 3.6 4.6 1.4 5.7 1.0 1.1 0.1 0.0 269.2 37.2 0.0 0.0 0.3 0.7 0.5 0.0 0.6 0.0 15.0 0.0 11.7 0.0 14.6 12.7 0.3 0.0 0.0 0.3 2.6 0.0 0.5 0.0 50.9 0.0 49.9 3.4 0.0 0.3 0.0 1.8 0.0 1.5 0.0 0.5 1.1 EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 122.8;Leydig cells: 93.5;Muller glia cells: 84.8;Peritubular cells: 107.2;Smooth muscle cells: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 159.7;fHDF/TERT166: 232.6;HSkMC: 155.3;hTERT-RPE1: 159.1;LHCN-M2: 134.5;U-138 MG: 114.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" 38.4 18.0 19.8 13.8 21.1 2.8 29.5 18.8 26.7 46.6 22.1 39.6 9.3 55.2 8.3 12.8 35.8 33.5 61.6 19.1 20.4 26.8 7.0 32.1 9.1 24.9 20.0 47.0 19.9 26.8 15.2 22.4 21.4 31.1 6.5 5.9 17.4 35.2 21.2 14.9 16.2 32.3 20.3 16.1 20.6 8.2 21.4 5.6 39.1 22.0 5.0 33.1 30.7 19.1 0.5 0.2 2.1 47.3 54.3 108.0 0.8 125.8 159.7 48.1 44.8 0.0 4.3 0.7 9.3 232.6 0.7 0.9 0.0 1.3 12.1 5.4 0.1 1.1 3.2 8.0 89.1 0.0 0.4 155.3 0.4 18.9 1.0 159.1 28.5 1.0 0.3 8.0 134.5 0.4 0.2 20.7 1.6 0.2 0.6 0.4 0.3 3.2 1.6 0.6 0.7 14.1 0.2 1.3 1.5 6.6 1.5 10.0 64.6 114.2 24.7 52.6 0.6 10.9 0.7 0.3 42.6 0.8 19.7 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.2 19.8 21.1 18.8 26.7 19.1 20.4 24.9 20.0 21.4 20.3 21.4 19.1 30.8 35.3 7.4 29.0 1.5 13.5 38.9 33.9 8.6 7.7 10.2 27.6 46.0 15.7 11.4 18.4 0.0 2.4 2.3 0.3 7.9 28.7 15.6 3.4 57.1 27.9 0.0 0.4 1.1 0.2 3.9 122.8 2.6 4.1 0.0 74.3 42.8 1.8 9.8 6.7 2.9 0.3 4.1 3.5 19.1 33.3 93.5 3.0 24.9 9.4 0.7 84.8 2.1 9.5 1.6 2.6 0.1 107.2 1.4 30.1 0.2 21.2 9.0 4.8 39.5 41.1 113.2 35.9 3.3 1.1 10.1 5.9 2.4 78.5 0.3 14.2 EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 414.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 241.8;Breast myoepithelial cells: 129.0;Distal tubular cells: 393.2;Oligodendrocytes: 173.4;Sertoli cells: 197.2;Smooth muscle cells: 130.9;Syncytiotrophoblasts: 263.9" "Cancer enriched" "Detected in all" 5 "breast cancer: 100.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 125.8;RPTEC TERT1: 68.6;SK-BR-3: 301.8;T-47d: 236.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA 14000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: AB_2680716, HPA056959: AB_2683288" "unprognostic (9.51e-3)" "unprognostic (2.21e-2)" "unprognostic (4.78e-3)" "unprognostic (3.25e-1)" "unprognostic (3.40e-1)" "unprognostic (9.70e-2)" "unprognostic (9.02e-2)" "unprognostic (1.13e-1)" "unprognostic (3.29e-3)" "unprognostic (1.21e-1)" "unprognostic (5.57e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.93e-7)" "unprognostic (2.00e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (2.29e-3)" 86.3 7.0 199.7 3.7 303.2 0.8 180.7 244.9 261.3 86.9 129.9 16.9 4.4 72.4 33.7 9.6 73.7 12.0 46.0 196.6 217.4 186.2 54.6 15.3 3.9 253.6 258.7 76.5 86.5 10.5 16.5 77.9 261.8 25.6 5.7 9.5 22.2 27.7 35.5 30.9 16.2 20.6 201.4 52.5 17.6 20.1 237.8 3.0 32.7 42.7 2.4 22.0 44.5 414.6 0.0 3.4 5.7 1.4 2.2 0.1 125.8 26.8 2.1 2.3 1.9 0.9 0.6 0.1 2.0 11.6 2.9 0.2 19.0 0.0 0.3 0.5 9.2 0.0 2.4 1.9 0.0 0.1 0.3 1.0 0.4 0.2 0.0 0.4 0.0 5.5 3.9 0.5 0.5 2.3 0.6 0.2 8.4 0.0 0.2 0.6 7.2 0.4 68.6 0.7 0.3 3.2 9.1 301.8 18.3 42.3 236.9 2.6 0.0 0.0 1.8 0.4 0.8 0.2 0.1 0.1 0.3 0.1 13.4 1.0 0.2 0.1 0.2 0.1 0.4 0.3 0.3 0.4 0.1 0.1 0.6 0.6 2.2 0.1 0.1 0.2 0.1 0.1 199.7 303.2 244.9 261.3 196.6 217.4 253.6 258.7 261.8 201.4 237.8 414.6 15.6 0.0 0.0 37.5 1.5 3.6 2.8 1.3 1.2 0.5 241.8 129.0 7.4 1.5 4.6 35.0 0.0 112.0 3.0 0.3 393.2 0.0 9.0 1.1 37.8 16.8 0.0 2.7 2.6 0.0 19.7 41.1 0.0 1.7 0.0 3.2 6.4 89.4 8.7 0.0 5.3 0.1 59.0 1.3 3.0 7.0 44.4 2.1 8.8 18.7 0.0 48.0 0.0 1.5 173.4 0.0 0.0 57.2 0.1 4.6 0.0 116.5 1.9 1.4 197.2 8.7 130.9 17.3 13.6 0.4 3.1 263.9 2.5 1.5 0.3 2.0 EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 372.4;NK-cells: 416.1;Pancreatic endocrine cells: 481.2;Urothelial cells: 431.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 370.3" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 1: Neutrophils - Mixed function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" 37.7 78.9 52.5 77.7 56.8 174.3 27.5 31.6 76.9 32.8 20.4 74.3 83.3 33.7 5.9 58.7 29.3 32.9 28.5 75.4 34.9 23.0 33.3 60.0 46.3 100.2 31.4 26.9 75.7 10.7 28.6 21.4 101.7 44.6 29.6 2.7 27.3 19.0 6.4 35.9 96.4 17.3 29.6 140.0 92.0 95.2 36.1 25.2 41.6 4.9 29.5 62.6 40.5 62.9 370.3 91.8 8.8 23.8 14.1 30.0 46.8 46.0 43.4 42.7 40.5 35.5 98.8 79.6 141.6 32.1 54.8 88.1 24.5 80.9 27.0 99.8 47.8 19.1 21.6 57.4 22.5 98.1 160.1 23.9 27.2 87.0 21.9 19.9 55.5 35.5 46.4 37.6 26.6 36.8 50.8 188.6 11.6 50.1 112.9 67.2 82.1 63.4 25.3 76.2 20.1 15.6 40.5 34.3 76.8 6.9 15.1 104.8 105.4 62.5 66.9 196.7 74.8 25.4 63.8 34.9 87.4 193.2 86.8 16.3 33.8 52.5 44.0 34.4 12.7 3.9 9.8 20.9 29.5 4.2 4.6 18.0 133.2 28.5 30.0 10.3 7.6 17.0 52.5 56.8 31.6 76.9 75.4 34.9 100.2 31.4 101.7 29.6 36.1 62.9 54.2 3.2 12.2 5.9 44.1 66.2 123.7 25.2 26.7 1.8 21.3 23.0 7.2 32.9 24.4 22.0 10.4 23.7 372.4 280.0 19.6 69.6 93.6 55.4 28.8 52.6 61.7 28.0 33.9 259.4 222.8 31.1 157.0 69.4 44.5 49.4 23.6 20.9 219.3 0.0 21.9 160.8 24.4 217.1 188.2 221.2 9.9 246.9 23.2 13.1 171.3 4.9 416.1 0.5 3.7 481.2 190.5 6.8 62.9 112.2 305.8 28.1 25.7 5.0 46.0 26.7 28.5 5.4 5.7 48.9 68.5 53.4 120.1 178.3 117.8 431.4 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EID2B "EID-3, FLJ38944" ENSG00000176401 "EP300 interacting inhibitor of differentiation 2B" Q96D98 19 39530987-39532852 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.1;Horizontal cells: 32.0;NK-cells: 27.8;Rod photoreceptor cells: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064185 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" "HPA064185: AB_2685207" "unprognostic (1.15e-1)" "unprognostic (8.53e-3)" "unprognostic (6.41e-3)" "unprognostic (1.08e-3)" "unprognostic (4.00e-1)" "unprognostic (7.08e-2)" "unprognostic (9.92e-4)" "unprognostic (2.45e-2)" "unprognostic (2.07e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.57e-4)" "unprognostic (6.80e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-2)" "unprognostic (1.78e-1)" "unprognostic (2.77e-1)" "unprognostic (4.20e-2)" 2.4 3.6 7.2 2.0 6.9 1.2 2.0 7.8 7.1 3.9 4.5 3.7 1.3 4.1 2.6 1.1 4.1 1.2 3.0 6.4 9.4 2.6 1.0 2.2 3.1 5.1 5.7 5.1 1.4 1.8 10.3 1.1 5.8 2.9 0.9 9.4 1.3 2.0 2.1 1.0 2.5 1.5 4.7 3.3 1.9 5.2 8.1 2.5 3.6 1.2 1.5 3.0 2.3 5.5 2.0 4.1 4.6 5.1 2.9 2.7 1.0 3.1 2.4 5.0 4.5 0.6 1.3 4.0 1.7 1.9 2.5 0.6 2.3 2.1 3.7 6.3 6.3 1.8 5.3 2.5 2.5 1.8 3.1 2.7 1.5 2.8 1.4 1.9 2.2 8.9 2.0 5.6 2.5 1.8 3.6 3.1 1.2 0.7 2.2 4.6 4.2 2.0 2.5 0.6 6.3 3.9 6.1 0.2 2.5 1.8 0.5 1.0 1.5 3.7 6.6 3.6 4.1 4.0 6.1 3.0 2.0 4.3 2.0 0.4 1.9 3.9 2.8 2.1 2.7 3.6 3.5 4.1 2.4 3.1 6.5 4.3 0.6 4.6 2.2 2.4 2.4 2.1 7.2 6.9 7.8 7.1 6.4 9.4 5.1 5.7 5.8 4.7 8.1 5.5 3.9 6.4 1.1 3.9 8.5 1.5 1.3 3.5 1.8 30.1 1.6 2.7 5.5 7.2 6.3 9.2 25.0 3.0 6.4 0.2 11.7 4.0 1.8 5.3 6.0 4.3 6.1 4.6 9.0 3.0 1.2 6.3 2.0 0.7 4.5 9.1 3.3 1.8 3.7 32.0 9.2 0.5 4.1 4.1 5.3 1.2 15.2 4.6 8.8 4.7 5.5 23.2 27.8 3.0 5.5 1.8 1.3 11.3 5.6 0.6 0.2 4.9 10.8 30.2 13.1 3.5 5.3 22.1 8.8 0.5 0.6 0.8 7.8 8.0 0.1 0.4 EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.4;Late spermatids: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA039993, HPA068855" Approved Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "Actin filaments" "CAB032234: AB_668909, HPA039993: AB_2676790, HPA068855: " "unprognostic (2.26e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.64e-2)" "unprognostic (2.18e-1)" "unprognostic (3.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.46e-8)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.67e-2)" 21.4 24.8 23.3 15.2 24.3 10.7 20.7 24.0 23.8 21.3 22.5 31.7 14.6 21.0 16.9 27.8 20.3 13.4 28.0 23.2 23.7 18.2 21.5 18.1 17.2 24.4 24.3 19.8 31.4 20.4 20.3 18.8 24.0 25.4 18.4 19.3 24.6 20.8 51.8 29.3 18.4 22.8 23.2 18.6 24.7 38.1 24.4 18.9 18.1 35.2 22.9 24.1 21.4 24.1 38.7 59.8 44.3 34.6 58.4 42.7 48.4 41.0 43.7 55.7 37.3 89.2 16.9 49.7 38.7 48.7 46.6 27.6 62.5 50.8 36.2 37.4 40.7 61.7 39.3 104.5 51.1 58.2 23.0 41.3 51.1 69.2 51.6 40.4 53.3 37.2 59.5 24.9 53.0 35.2 28.8 61.7 49.1 59.8 38.9 52.9 69.9 43.2 50.0 32.7 34.3 37.4 34.1 53.8 42.6 39.6 31.3 23.4 52.8 40.1 47.0 35.4 49.7 50.9 65.7 74.7 33.9 47.9 38.6 56.6 53.9 38.8 32.1 48.1 44.6 31.1 31.6 32.6 52.5 25.3 30.2 32.9 7.7 30.8 52.2 38.6 43.8 43.2 23.3 24.3 24.0 23.8 23.2 23.7 24.4 24.3 24.0 23.2 24.4 24.1 19.9 12.8 14.8 9.8 17.5 35.9 18.9 32.0 15.4 22.6 28.0 18.7 33.0 14.3 27.0 22.0 66.7 40.9 27.8 23.4 19.6 29.0 196.4 22.3 23.9 19.9 24.0 8.2 6.6 33.4 25.0 24.6 14.8 17.6 31.6 16.9 25.7 34.4 24.3 10.1 6.5 24.8 28.5 20.7 28.0 299.6 23.3 16.5 23.2 2.8 29.5 23.2 16.5 6.0 8.8 26.7 27.1 24.8 28.4 21.2 23.0 27.6 24.9 58.9 19.7 17.0 34.9 71.5 38.9 14.5 34.8 46.1 24.3 23.8 20.5 14.4 EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Group enriched" "Detected in many" 12 "Early spermatids: 353.0;Late spermatids: 977.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA029090: AB_10671359" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (4.05e-1)" "unprognostic (5.75e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (2.66e-2)" "unprognostic (3.45e-2)" "unprognostic (5.92e-2)" "unprognostic (1.64e-2)" "unprognostic (4.29e-3)" 4.1 2.7 1.9 3.1 2.8 4.2 2.9 5.8 6.1 3.1 1.9 3.4 1.7 4.5 1.3 2.9 2.4 3.5 4.0 1.9 5.4 5.0 1.6 2.2 2.8 7.2 4.6 4.4 3.3 3.7 1.8 1.8 8.2 2.6 2.6 2.8 1.9 3.0 1.3 1.9 1.6 7.2 4.1 2.3 9.1 28.3 5.5 4.3 2.2 3.1 3.1 3.5 2.0 7.2 22.7 11.6 4.2 5.9 21.7 14.2 10.0 17.1 22.3 17.4 25.1 23.6 14.4 14.2 30.9 23.4 38.9 7.4 13.4 6.0 21.9 15.8 5.8 6.9 4.6 7.5 14.6 18.2 19.9 16.6 8.7 26.3 21.4 24.2 9.1 3.7 5.8 0.1 28.7 7.6 8.1 7.9 8.1 17.5 7.8 0.0 12.0 0.0 7.3 4.0 3.4 6.4 17.7 4.6 14.4 6.5 10.0 11.9 12.0 21.2 15.0 44.8 38.9 21.6 0.3 33.3 7.2 6.2 15.4 14.9 1.4 1.5 12.4 1.5 8.7 2.2 8.4 11.9 1.0 3.5 5.0 8.3 0.7 8.8 1.4 1.0 11.3 5.0 1.9 2.8 5.8 6.1 1.9 5.4 7.2 4.6 8.2 4.1 5.5 7.2 16.6 0.0 0.5 4.9 4.4 17.1 8.5 7.8 10.8 2.5 2.1 2.7 9.5 0.0 1.8 1.8 0.0 1.2 18.1 1.6 1.9 6.4 353.0 0.9 7.7 12.8 4.9 2.1 7.1 7.5 1.9 11.7 8.6 0.6 2.5 2.6 3.3 2.5 8.9 0.0 8.8 0.8 2.0 3.8 7.2 977.9 12.8 4.5 10.6 3.7 7.9 8.0 28.8 4.0 10.1 19.6 6.1 11.3 3.7 8.2 1.7 21.1 3.4 2.7 46.0 9.6 11.6 54.3 10.0 2.3 21.6 0.7 15.7 2.2 1.8 5.7 ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 53.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 34.3;Granulosa cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" 12.2 3.7 1.8 14.6 1.6 53.1 9.6 2.8 2.0 9.4 2.6 18.1 14.2 10.6 2.0 11.7 12.1 9.3 5.6 1.8 2.4 6.0 2.8 15.9 18.3 2.8 2.4 17.5 2.6 4.8 4.2 23.7 2.4 6.1 17.7 0.6 5.5 4.1 2.0 10.9 17.0 10.6 1.5 18.1 20.3 2.6 2.9 19.6 3.9 3.6 18.0 18.8 9.1 3.1 56.0 20.7 3.7 0.4 9.1 19.3 52.6 25.3 32.1 30.4 33.4 28.7 38.9 28.6 49.5 34.8 42.3 35.2 20.5 30.0 29.9 31.0 16.8 56.7 27.3 13.6 20.2 49.7 69.3 20.4 32.6 49.1 48.0 19.0 30.0 6.5 22.0 7.7 16.5 32.8 8.2 28.2 2.4 28.4 19.4 17.6 6.5 12.2 18.3 63.9 13.6 6.0 22.8 21.9 6.9 19.1 11.0 46.9 27.6 21.2 16.6 39.5 47.7 4.2 1.8 22.6 24.6 44.8 5.0 1.6 4.0 5.8 7.1 7.6 5.6 2.6 4.2 6.1 4.5 2.7 4.2 4.8 6.9 6.5 5.5 2.7 4.8 4.2 1.8 1.6 2.8 2.0 1.8 2.4 2.8 2.4 2.4 1.5 2.9 3.1 10.7 9.6 4.4 0.0 8.0 13.6 8.2 2.9 9.1 0.0 2.1 1.5 0.8 0.0 4.4 0.0 0.0 10.6 12.2 24.1 0.0 2.3 0.1 8.9 3.8 8.4 9.0 7.4 0.2 4.0 34.3 6.4 17.9 17.1 1.3 27.5 6.4 1.0 9.7 0.0 0.3 8.3 2.0 12.2 9.2 0.6 1.8 14.8 3.6 5.6 13.1 0.0 16.5 0.0 1.2 9.1 17.4 1.2 2.0 7.5 11.6 0.3 5.4 0.0 6.6 2.6 2.5 0.0 4.0 6.5 10.4 11.2 9.5 5.2 7.1 18.9 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" 78.5 54.7 77.2 39.8 115.6 52.9 66.6 121.1 116.9 57.1 61.4 63.9 51.6 46.5 30.6 176.6 38.9 42.4 47.2 76.8 93.2 59.7 45.8 59.6 40.1 152.0 110.1 28.9 55.4 46.2 27.2 51.0 140.7 58.7 48.6 8.4 72.7 48.8 24.1 201.9 55.4 50.8 114.8 57.1 70.6 18.6 107.7 22.2 66.8 28.0 55.7 68.5 86.8 165.7 108.0 119.5 22.6 44.8 148.4 138.2 70.2 125.2 154.5 153.5 122.4 105.9 182.5 73.9 94.3 193.6 130.3 119.4 79.7 152.2 93.2 94.6 53.9 96.6 77.3 77.1 128.2 84.2 98.0 106.2 168.2 180.9 198.4 114.8 155.0 27.7 68.1 54.8 178.5 79.5 19.9 69.5 33.5 136.9 120.2 43.6 59.9 89.7 195.5 128.7 27.4 28.8 73.7 258.4 105.8 66.8 121.2 82.4 132.2 129.7 82.5 161.2 161.3 26.6 31.2 35.4 127.8 85.2 120.1 134.9 189.6 172.7 105.1 180.0 93.4 109.0 98.4 103.2 212.8 94.2 63.5 88.0 133.0 114.7 179.6 148.8 113.8 203.1 77.2 115.6 121.1 116.9 76.8 93.2 152.0 110.1 140.7 114.8 107.7 165.7 44.0 19.2 12.5 7.5 28.1 15.6 25.9 61.1 29.6 5.7 60.3 37.5 4.7 34.3 40.2 40.5 10.4 93.4 36.0 114.0 7.9 91.5 3.4 22.9 26.3 43.6 19.2 67.8 3.8 100.1 127.4 26.1 48.4 45.2 21.0 52.6 24.7 16.7 74.9 3.3 3.4 33.8 46.8 46.3 37.5 4.6 20.2 41.5 12.4 7.5 92.5 13.7 32.0 3.0 66.1 133.3 63.9 25.6 19.0 44.7 66.0 23.3 14.5 9.5 19.7 10.0 39.7 8.4 11.2 70.1 31.0 95.9 31.5 50.8 47.2 49.2 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 107.2;kidney: 95.2;liver: 263.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 209.3;Hepatocytes: 134.8;Intestinal goblet cells: 77.1;Proximal enterocytes: 87.0" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.3;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.3" "Cell line enhanced" "Detected in all" "RT4: 57.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" NA NA 5900000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" 8.2 7.7 5.0 11.4 7.3 8.0 12.4 7.1 6.7 7.3 7.1 94.6 72.1 6.3 7.7 11.3 5.7 12.1 7.7 5.1 6.3 95.2 263.7 6.5 5.5 7.6 7.3 6.7 4.9 7.7 5.0 5.6 7.8 37.7 107.2 9.4 10.7 4.4 15.0 8.1 68.4 9.7 6.5 6.0 42.3 8.6 7.3 4.6 6.1 9.1 5.6 16.9 7.2 9.0 9.5 7.8 8.2 15.1 16.5 15.5 9.4 9.6 7.9 6.4 7.1 5.6 10.9 10.6 4.7 12.8 6.0 10.8 8.5 14.1 7.2 8.8 4.0 7.9 5.7 30.9 15.5 4.7 8.8 12.9 14.0 8.7 18.2 8.8 13.1 17.1 8.8 15.4 9.7 13.6 5.4 5.6 2.5 8.5 15.7 6.0 8.0 5.2 11.4 57.1 5.8 6.0 16.6 12.9 9.2 6.4 18.7 4.1 10.8 12.6 12.7 7.5 7.2 10.1 16.9 8.3 8.0 8.8 11.5 18.3 1.2 9.4 2.5 2.3 1.3 1.4 1.3 1.8 1.7 1.5 2.1 2.1 0.1 0.5 1.4 0.9 1.6 1.3 5.0 7.3 7.1 6.7 5.1 6.3 7.6 7.3 7.8 6.5 7.3 9.0 8.0 16.0 6.7 8.1 4.9 3.7 6.2 8.9 5.2 6.6 15.0 7.9 5.2 10.0 11.3 7.3 4.2 8.2 4.3 209.3 25.4 6.9 19.5 10.0 13.6 7.0 16.2 36.6 5.9 12.9 6.7 7.9 23.0 25.8 1.3 9.6 9.7 134.8 6.2 10.1 8.2 77.1 14.2 9.7 1.9 12.7 2.8 5.2 5.4 11.2 5.4 4.9 8.2 2.0 11.3 9.1 58.4 5.7 3.6 28.5 87.0 63.1 6.4 12.2 13.1 6.0 5.9 27.2 19.1 8.5 3.4 3.3 4.9 10.3 60.9 39.0 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37683843-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.5;Peritubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-937: 122.2;WM-115: 114.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" 23.1 40.3 46.3 4.2 41.4 4.5 11.3 38.4 82.3 38.5 27.3 10.5 13.4 41.7 13.6 8.4 28.1 10.1 27.4 45.4 67.5 16.4 10.9 27.1 4.9 81.9 50.4 34.0 9.4 8.0 9.4 4.9 83.2 34.5 8.4 14.3 13.8 41.0 122.9 3.2 13.2 29.9 50.9 17.2 5.7 13.0 58.5 11.4 31.0 72.1 3.0 8.8 17.0 38.9 0.2 77.9 6.4 0.1 57.9 20.8 0.1 5.9 0.0 3.0 9.1 7.7 5.1 0.0 84.2 86.0 88.7 0.2 1.8 0.7 0.0 0.1 9.8 34.9 10.2 49.5 0.5 29.1 0.2 35.1 0.0 21.1 0.4 20.0 0.0 34.3 0.0 25.2 51.6 5.1 11.3 25.1 24.0 0.0 11.6 35.2 22.3 30.6 47.3 19.3 8.4 29.3 0.0 3.8 28.2 15.3 0.1 20.4 0.0 16.6 27.8 46.6 36.7 33.8 15.4 0.5 75.5 122.2 114.7 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.4 0.0 0.8 0.0 2.2 0.0 0.1 46.3 41.4 38.4 82.3 45.4 67.5 81.9 50.4 83.2 50.9 58.5 38.9 6.4 32.1 46.2 12.7 1.4 1.3 7.8 3.5 1.2 5.7 1.1 10.5 20.7 7.2 12.7 1.8 0.0 0.5 6.8 5.1 17.6 10.0 0.3 5.5 31.8 2.4 3.6 25.6 36.9 8.0 0.2 15.0 1.5 5.9 2.5 95.5 7.5 10.7 3.1 11.8 39.3 5.1 0.0 1.6 2.0 2.1 28.3 3.1 28.4 14.0 14.2 13.3 2.1 24.6 13.0 19.7 6.9 98.9 0.2 14.6 19.3 14.8 5.7 7.2 6.6 46.4 23.9 0.3 1.8 0.5 0.3 0.1 1.2 28.7 6.4 2.6 EPHX1 EPHX ENSG00000143819 "Epoxide hydrolase 1" P07099 1 225810124-225845563 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 1178.6;liver: 1705.1" "Cell type enhanced" "Detected in many" "Granulosa cells: 349.9;Hepatocytes: 757.6;Theca cells: 1042.6" "Cancer enriched" "Detected in all" 6 "liver cancer: 1047.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 1161.8;SiHa: 413.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020593, HPA048847" Enhanced NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA020593: AB_10601373, HPA048847: AB_2680538" "unprognostic (2.85e-2)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.53e-3)" "unprognostic (2.50e-1)" "unprognostic (6.60e-2)" "unprognostic (3.92e-2)" "prognostic favorable (7.02e-5)" "unprognostic (1.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.32e-4)" "unprognostic (8.10e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "unprognostic (1.88e-2)" 245.8 1178.6 233.5 23.6 252.5 22.7 163.7 239.0 249.3 188.3 345.8 82.0 102.2 108.1 97.6 159.6 153.8 96.5 94.0 221.3 233.7 110.7 1705.1 146.8 39.1 225.3 234.9 329.1 536.1 147.7 105.8 32.9 223.6 113.2 52.5 30.7 143.6 128.1 142.5 71.5 52.8 109.6 210.1 55.7 99.9 74.3 258.4 25.9 171.1 95.6 33.4 135.4 140.4 227.2 32.1 202.3 12.3 108.5 1161.8 120.2 24.3 29.7 49.2 28.1 35.1 38.8 293.6 1.3 128.7 147.3 30.6 38.1 32.7 16.8 12.1 7.8 46.5 21.8 83.5 282.7 129.8 12.9 15.1 109.2 40.0 74.6 6.3 116.5 22.1 13.4 14.5 27.3 50.4 30.3 13.5 31.0 61.6 178.1 79.4 27.8 15.2 92.9 91.1 132.5 98.3 13.0 413.0 192.1 51.3 32.1 131.7 43.5 46.8 41.9 35.4 54.5 59.0 9.1 38.9 4.1 63.5 14.2 59.5 0.0 2.6 0.1 0.2 0.7 0.4 0.1 0.3 0.2 0.6 0.2 0.5 0.3 0.2 0.7 0.3 0.9 0.3 0.8 233.5 252.5 239.0 249.3 221.3 233.7 225.3 234.9 223.6 210.1 258.4 227.2 196.9 0.0 14.0 41.1 5.7 19.6 121.8 244.2 74.0 8.8 29.7 27.4 1.2 102.9 255.5 51.5 29.2 46.6 3.4 34.5 17.6 95.3 10.2 142.9 32.2 82.7 10.8 7.0 3.1 73.0 7.6 175.6 30.5 93.4 5.7 349.9 88.2 757.6 149.1 1.7 5.0 17.5 103.7 30.9 28.7 28.4 311.3 25.8 42.7 23.4 9.6 99.2 0.0 7.1 19.4 45.5 27.2 159.1 9.5 40.4 63.4 128.9 174.3 10.1 223.5 29.3 146.9 4.4 5.1 129.0 17.6 22.8 4.7 1042.6 31.5 108.5 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 ESRP2 "FLJ21918, RBM35B" ENSG00000103067 "Epithelial splicing regulatory protein 2" Q9H6T0 16 68229033-68238102 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 55.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 36.3;Gastric mucus-secreting cells: 44.9;Late spermatids: 82.4;Syncytiotrophoblasts: 58.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 55.5;MCF7: 113.2;RT4: 60.4;SK-BR-3: 59.8;T-47d: 90.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040751, HPA048597, HPA048618" Uncertain Enhanced Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA040751: AB_2677115, HPA048597: AB_2680458, HPA048618: AB_2680463" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-2)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (8.80e-2)" "prognostic favorable (1.30e-6)" "unprognostic (1.24e-1)" "unprognostic (3.16e-1)" "unprognostic (9.04e-3)" "unprognostic (8.75e-3)" 0.6 0.1 0.2 2.2 0.1 0.0 9.6 0.5 0.3 7.6 0.7 18.1 9.9 1.1 7.4 55.2 4.9 4.1 0.1 0.2 0.0 9.9 38.8 13.3 0.0 0.1 0.1 0.2 28.9 13.4 3.3 8.0 0.1 11.6 14.7 0.0 17.8 2.6 0.2 36.5 8.2 0.5 0.0 0.0 27.0 10.8 0.3 3.4 16.7 0.0 7.1 13.0 19.2 0.2 38.6 0.2 0.1 0.0 0.0 0.0 55.5 0.2 0.0 0.1 0.2 36.7 19.1 0.0 1.7 0.0 0.0 40.4 0.1 30.1 0.0 0.1 24.1 0.1 12.5 30.9 0.6 0.0 0.2 0.0 43.4 0.0 16.4 0.1 0.0 0.1 0.1 0.0 0.0 113.2 0.0 0.3 4.1 31.4 12.0 0.1 0.0 0.2 14.5 60.4 4.2 0.0 19.6 59.8 0.1 5.4 90.1 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.6 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.2 0.2 19.2 17.2 0.0 0.3 6.4 5.3 6.8 5.7 0.8 10.7 6.9 1.0 20.0 11.1 23.9 0.0 36.3 0.3 18.8 0.0 11.0 29.1 7.3 1.4 0.4 8.4 0.0 0.0 14.0 5.5 0.5 44.9 13.8 0.0 0.6 0.4 31.1 2.7 0.0 0.0 25.3 8.2 0.8 0.8 82.4 0.9 0.2 1.8 0.0 0.6 0.3 1.0 0.0 0.0 13.7 8.5 0.0 0.3 7.9 5.1 5.6 4.2 0.2 0.0 0.2 0.7 10.4 1.2 27.2 8.5 58.4 0.5 0.0 18.3 8.9 ETV7 "TEL-2, TEL2" ENSG00000010030 "ETS variant transcription factor 7" Q9Y603 6 36354091-36387800 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.0;skin 1: 15.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Cytotrophoblasts: 28.8;Exocrine glandular cells: 23.8;Proximal enterocytes: 21.5;Spermatogonia: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9;T-reg: 16.3" "Group enriched" "Detected in many" 4 "granulocytes: 18.9;monocytes: 5.7;T-cells: 16.3" "Cell line enhanced" "Detected in some" "BEWO: 27.1;BJ hTERT+ SV40 Large T+: 14.7;BJ hTERT+ SV40 Large T+ RasG12V: 27.8;HDLM-2: 59.7" "Low region specificity" "Detected in all" HPA029033 Uncertain Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA029033: AB_10601375" "unprognostic (1.67e-2)" "prognostic favorable (5.16e-4)" "unprognostic (9.48e-2)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-3)" "unprognostic (9.08e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "prognostic favorable (5.32e-4)" "unprognostic (6.81e-3)" "unprognostic (1.11e-1)" "unprognostic (1.69e-3)" "unprognostic (5.54e-2)" "unprognostic (4.93e-1)" "unprognostic (1.27e-2)" "prognostic favorable (2.95e-6)" 1.9 2.1 1.5 6.9 1.5 0.9 2.1 1.0 1.7 2.1 1.4 3.3 16.0 1.0 1.3 3.6 2.2 3.4 0.4 1.5 1.4 2.3 2.9 4.9 5.3 2.2 1.2 1.5 1.6 2.2 3.8 3.6 2.1 2.9 2.6 0.4 8.6 1.5 0.2 15.4 12.7 1.0 2.1 3.1 6.2 1.1 1.4 4.0 1.2 0.3 3.9 5.5 2.5 1.4 3.2 0.0 0.2 0.1 0.0 0.2 27.1 0.0 9.2 14.7 27.8 0.5 6.2 0.1 0.7 0.2 2.3 3.3 0.4 1.7 0.7 59.7 0.5 0.5 0.0 0.0 1.8 0.0 0.3 1.2 2.4 0.7 0.2 0.0 0.4 0.0 0.1 0.2 0.3 0.1 0.2 0.3 0.2 0.3 0.1 6.1 0.1 0.2 0.2 1.1 0.8 0.0 0.6 2.1 0.5 0.0 3.1 0.6 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 2.7 0.4 0.0 3.7 0.3 1.6 5.7 3.9 3.3 5.4 2.2 0.9 2.4 1.0 1.4 18.9 0.6 1.9 0.0 16.3 2.5 1.5 1.5 1.0 1.7 1.5 1.4 2.2 1.2 2.1 2.1 1.4 1.4 1.4 19.2 14.8 0.3 1.2 2.0 2.2 8.0 6.2 0.2 2.5 2.7 0.5 7.2 7.1 0.0 0.0 28.8 0.7 6.6 0.0 12.4 0.4 0.4 1.4 1.1 3.6 0.0 0.5 23.8 6.6 2.7 8.2 0.7 2.5 1.7 0.0 0.4 2.9 0.0 0.3 6.5 6.1 1.3 1.6 0.5 1.5 1.0 3.6 0.0 6.5 3.1 1.0 0.0 0.3 13.4 7.8 1.2 5.6 4.8 21.5 1.3 3.0 0.6 0.0 1.0 5.5 0.9 26.8 6.4 3.7 8.5 3.6 0.7 7.6 4.8 EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 233.2;Kupffer cells: 522.3;Langerhans cells: 169.8;Macrophages: 271.9;monocytes: 426.4;T-cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Cell line enhanced" "Detected in many" "Daudi: 87.9;HL-60: 99.9;HMC-1: 133.3;Karpas-707: 96.4;NB-4: 79.4;RPMI-8226: 147.7;THP-1: 124.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" 24.6 11.0 6.4 100.9 7.3 189.0 13.8 7.3 11.6 13.1 8.7 27.9 23.7 7.4 4.3 11.8 7.8 30.5 6.7 6.3 8.4 5.1 24.9 61.1 159.5 13.3 10.3 5.5 3.0 3.8 1.8 15.4 10.8 7.4 30.5 1.2 11.8 6.1 2.0 5.1 39.2 17.0 7.7 158.8 33.7 3.7 8.5 76.4 5.3 12.2 169.8 38.5 4.1 11.1 0.6 0.7 0.0 0.0 6.5 8.3 0.1 0.8 5.8 6.7 12.4 0.0 3.4 87.9 0.1 5.5 26.4 0.6 0.0 1.2 7.5 0.1 0.0 2.1 0.0 0.0 66.0 99.9 133.3 15.3 0.0 3.9 5.3 2.2 6.9 7.3 1.4 96.4 19.8 0.0 29.4 79.4 0.1 0.0 0.0 51.0 0.4 147.7 0.3 0.2 0.0 0.1 0.4 0.2 0.5 0.0 0.0 124.8 7.2 1.9 0.2 0.7 7.0 18.4 0.9 18.9 8.6 34.0 2.2 1005.3 328.9 798.7 79.2 240.1 76.8 183.6 120.8 102.8 149.9 146.2 91.9 87.5 1366.0 44.2 381.9 86.3 173.6 251.4 6.4 7.3 7.3 11.6 6.3 8.4 13.3 10.3 10.8 7.7 8.5 11.1 2.1 0.0 14.8 0.7 233.2 5.4 0.7 0.7 1.8 0.2 1.5 1.7 1.0 2.8 6.7 1.8 0.0 0.6 129.0 1.3 0.0 0.3 8.3 0.1 0.3 5.6 0.0 6.5 2.7 0.0 0.8 4.0 1.5 0.4 82.2 0.0 7.5 2.3 89.1 0.0 3.1 0.1 2.0 522.3 169.8 9.0 0.0 271.9 37.4 11.2 426.4 0.0 117.4 4.0 31.7 1.0 0.0 0.4 110.4 0.4 0.1 1.1 2.4 0.8 19.7 1.2 1.9 0.4 0.4 0.4 3.7 0.3 170.9 0.0 1.3 1.1 F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 142.8;liver: 176.2;placenta: 46.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Cytotrophoblasts: 82.7;Hepatocytes: 253.4;Syncytiotrophoblasts: 59.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Group enriched" "Detected in some" 23 "Hep G2: 32.8;OE19: 125.5" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.4" "Group enriched" "Detected in all" 7 "amygdala: 39.9;basal ganglia: 35.0;cerebral cortex: 67.9;hippocampal formation: 61.4;olfactory bulb: 27.6" HPA002036 Approved "Golgi apparatus" "Secreted to blood" NA NA 7670000000 13000000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" 1.1 0.0 0.3 3.2 1.4 3.7 0.6 4.4 1.3 0.1 142.8 0.3 0.9 0.1 0.2 0.2 3.5 17.6 2.7 4.4 1.6 1.5 176.2 0.9 2.2 1.9 2.2 0.0 0.8 0.0 1.6 46.9 2.4 1.3 0.6 1.0 6.2 0.0 0.2 1.3 0.3 1.1 0.8 1.8 4.9 0.5 2.2 0.5 0.4 0.2 2.3 3.8 0.1 4.2 0.0 0.6 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 32.8 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 125.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 4.1 8.1 0.0 0.2 0.0 0.0 1.4 0.2 0.4 0.0 0.3 0.0 7.0 0.0 0.0 0.0 6.2 1.1 0.3 1.4 4.4 1.3 4.4 1.6 1.9 2.2 2.4 0.8 2.2 4.2 0.0 3.2 0.6 1.6 0.7 0.1 6.1 0.0 0.0 0.3 0.7 0.3 9.4 74.4 1.9 0.0 2.1 82.7 0.1 0.3 0.0 2.4 2.4 0.9 0.0 2.4 25.2 0.0 5.4 0.2 2.3 5.3 4.1 0.2 0.0 2.8 3.6 253.4 5.3 0.0 2.6 0.1 0.0 12.3 0.4 0.3 0.0 7.1 3.6 0.0 18.2 1.0 2.1 0.5 1.0 1.9 0.0 0.0 0.1 1.8 0.0 0.2 3.1 0.1 0.0 2.4 0.2 0.5 0.5 0.0 0.0 59.5 2.5 0.0 0.0 11.8 F8A1 "DXS522E, F8A" ENSG00000277203 "Coagulation factor VIII associated 1" P23610 X 154886349-154888061 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (6.72e-2)" "prognostic favorable (1.67e-6)" "unprognostic (2.92e-2)" "unprognostic (2.57e-1)" "unprognostic (6.88e-2)" "unprognostic (6.61e-2)" "unprognostic (4.18e-3)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (9.23e-3)" "unprognostic (1.20e-1)" "unprognostic (1.80e-1)" "unprognostic (3.68e-2)" "unprognostic (6.28e-2)" "unprognostic (6.16e-2)" "unprognostic (5.61e-2)" "unprognostic (2.69e-1)" 23.1 23.7 30.6 12.9 30.1 33.1 21.0 25.4 39.5 13.8 22.4 19.6 15.2 18.8 22.7 17.6 13.3 7.4 25.5 31.7 29.8 22.8 44.6 17.1 19.3 30.8 28.2 8.8 22.2 14.0 13.7 13.0 31.9 16.3 14.9 14.8 21.8 18.1 27.6 16.5 20.1 14.8 26.2 23.1 15.6 5.8 31.3 20.6 19.6 18.1 20.0 19.4 13.3 32.2 106.4 47.2 9.1 14.7 31.3 14.8 0.2 27.5 22.9 27.8 36.0 18.6 40.2 11.4 87.9 16.7 36.3 11.0 13.3 12.7 22.8 63.3 6.3 11.6 13.3 18.8 9.5 21.1 5.6 28.6 11.6 9.2 5.2 20.6 6.0 29.1 1.2 41.8 16.2 53.8 34.0 94.9 16.3 0.0 54.7 64.1 9.0 10.0 31.8 35.9 45.7 19.0 16.7 20.1 36.4 0.0 23.7 41.6 17.1 15.7 36.0 11.6 22.1 41.6 43.9 101.4 8.3 76.7 36.0 0.0 3.0 6.8 2.9 3.1 1.6 1.5 3.2 3.5 3.5 2.5 3.6 4.0 6.0 0.8 1.2 4.2 1.6 1.7 30.6 30.1 25.4 39.5 31.7 29.8 30.8 28.2 31.9 26.2 31.3 32.2 5.5 12.8 2.6 5.5 14.4 6.6 5.2 1.8 2.2 12.1 14.4 12.4 13.6 27.1 1.5 40.5 6.2 4.0 19.5 11.9 49.0 2.7 0.3 9.2 11.9 7.1 6.7 9.5 7.2 2.0 6.2 7.4 6.6 9.7 5.7 7.6 7.5 24.6 11.2 3.3 6.1 10.2 4.1 27.3 16.8 1.5 10.8 16.9 10.6 7.5 16.7 7.3 30.9 6.6 9.6 2.5 5.7 12.4 4.7 3.1 10.4 57.9 2.7 7.0 6.6 4.6 6.1 0.4 1.5 7.6 6.5 1.6 19.0 8.9 9.8 2.8 FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 128.5;Proximal enterocytes: 87.4;Spermatocytes: 89.0" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 37.5;OE19: 18.8;RT4: 42.4;SK-BR-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" 7.5 14.2 23.5 2.9 28.4 10.4 9.5 25.6 29.6 7.5 29.3 18.9 22.0 3.9 9.1 8.7 12.0 5.2 5.0 24.6 23.3 20.0 32.8 7.8 2.5 32.1 25.4 3.9 22.4 24.6 19.0 3.4 28.7 44.1 15.2 5.5 17.4 7.1 9.5 12.1 22.0 2.3 27.9 3.3 17.1 46.8 26.4 7.1 38.6 5.6 2.7 6.9 8.2 45.8 5.0 1.2 0.8 1.0 1.2 0.8 37.5 1.0 0.5 0.5 0.8 7.3 11.4 0.3 3.9 0.7 0.4 16.2 0.7 2.3 0.2 2.2 5.4 0.1 0.2 3.5 0.8 1.4 2.8 0.6 10.7 0.4 1.3 0.4 0.0 0.9 0.1 0.8 0.0 10.7 0.8 2.2 3.2 18.8 0.4 0.9 0.4 0.2 9.0 42.4 4.8 3.6 5.6 21.2 0.2 0.9 14.6 14.5 0.0 0.1 0.6 1.1 0.7 2.1 1.0 0.6 0.1 13.4 0.4 0.0 6.9 29.1 0.4 1.9 0.2 0.1 0.4 0.2 8.2 0.1 0.6 0.6 0.4 0.5 1.0 8.8 0.2 1.4 23.5 28.4 25.6 29.6 24.6 23.3 32.1 25.4 28.7 27.9 26.4 45.8 1.2 22.4 13.2 6.5 2.4 5.2 29.0 6.8 10.2 15.5 15.4 9.0 2.9 27.1 11.0 22.0 43.8 16.3 7.3 51.6 0.0 12.4 50.7 9.5 1.9 1.8 15.5 6.6 15.7 6.4 8.7 3.7 37.8 6.0 0.0 6.3 0.4 37.1 2.8 1.7 11.4 38.2 10.2 2.5 4.2 128.5 7.5 3.3 5.4 1.9 2.5 7.3 0.0 7.5 45.1 4.2 41.3 4.5 0.7 20.1 87.4 22.6 5.2 14.5 0.0 2.9 3.2 89.0 23.0 6.4 6.0 12.4 1.2 1.3 55.2 18.9 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.6;Extravillous trophoblasts: 138.4;Rod photoreceptor cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.7" "Group enriched" "Detected in many" 4 "B-cells: 8.7;granulocytes: 5.7;T-cells: 2.1" "Cell line enhanced" "Detected in all" "ASC diff: 283.2;HHSteC: 243.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" 105.0 72.3 37.1 23.4 37.3 5.1 72.5 29.6 50.7 31.2 55.3 27.5 4.8 27.9 31.7 9.5 26.7 12.1 88.9 36.9 35.2 29.4 23.7 45.4 21.6 34.8 33.7 35.7 25.4 11.4 14.1 64.0 38.9 21.3 4.6 15.0 14.3 13.1 45.2 13.4 28.1 19.4 29.8 22.3 22.7 13.4 37.3 4.3 18.1 14.8 20.9 36.7 21.4 35.3 37.3 11.4 3.6 22.5 283.2 57.0 71.5 73.1 177.9 77.0 73.7 16.2 13.3 27.5 46.5 147.1 60.0 20.1 13.7 199.4 40.8 7.9 7.6 22.7 48.9 32.8 243.6 2.1 4.5 62.5 85.2 92.4 175.4 46.8 90.1 14.3 22.2 50.8 132.6 42.7 8.3 11.3 10.7 4.1 29.4 46.4 142.8 76.8 86.0 13.0 5.7 7.2 83.4 11.2 77.9 29.9 16.4 5.0 61.2 74.5 51.1 22.0 32.6 15.5 8.0 35.0 62.4 11.2 55.2 0.0 0.7 5.7 1.6 1.2 1.4 7.7 1.4 2.1 0.6 8.7 0.1 0.5 0.3 0.6 0.8 0.0 0.4 0.6 37.1 37.3 29.6 50.7 36.9 35.2 34.8 33.7 38.9 29.8 37.3 35.3 164.6 32.1 5.2 54.5 39.0 6.8 8.2 15.6 2.8 11.2 23.3 26.2 19.5 18.6 2.0 5.5 8.4 38.9 15.2 35.7 1.9 46.4 17.4 8.2 31.2 57.7 6.7 13.0 31.6 20.6 138.4 31.3 16.8 13.1 7.0 12.4 20.3 9.8 19.7 1.7 10.0 21.0 0.0 3.9 43.0 14.0 28.6 16.5 35.6 8.4 8.0 48.5 5.2 17.1 17.6 16.4 6.7 17.7 13.1 10.7 6.3 13.9 2.9 120.3 19.7 97.3 90.2 2.0 5.5 3.5 5.5 68.0 17.6 16.1 15.8 4.3 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM124A FLJ30707 ENSG00000150510 "Family with sequence similarity 124 member A" Q86V42 13 51222334-51284239 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 59.1;choroid plexus: 26.7;retina: 25.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 232.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HAP1: 18.0;HUVEC TERT2: 10.6;NTERA-2: 35.1;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048182 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA048182: AB_2680301" "unprognostic (3.94e-3)" "unprognostic (8.76e-2)" "unprognostic (8.05e-2)" "unprognostic (1.05e-2)" "unprognostic (3.34e-1)" "unprognostic (8.37e-2)" "unprognostic (2.59e-2)" "unprognostic (2.08e-3)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (2.43e-2)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (7.38e-3)" "unprognostic (4.51e-2)" "unprognostic (4.54e-3)" "unprognostic (1.05e-2)" 4.6 1.8 13.2 2.7 32.1 0.2 2.9 24.0 22.0 2.2 26.7 8.1 0.6 3.1 4.6 1.2 3.1 2.4 4.9 14.8 20.8 3.7 0.7 1.9 0.8 33.8 27.4 0.8 1.4 0.6 1.3 3.6 31.3 4.6 1.3 25.7 7.3 4.4 1.0 1.0 2.0 5.2 18.4 8.3 3.3 1.2 25.9 3.1 2.4 1.3 0.5 4.5 1.6 59.1 0.0 1.7 1.2 1.1 0.3 0.1 0.1 0.2 0.6 0.2 0.2 0.1 0.6 0.6 0.0 0.0 2.2 0.1 18.0 0.2 0.1 0.1 2.7 0.1 0.5 0.0 1.4 0.9 1.1 0.4 0.2 0.5 0.0 0.0 10.6 4.8 0.1 0.1 0.0 0.3 4.6 0.3 35.1 0.3 2.8 1.0 0.1 2.6 0.0 0.1 2.5 13.3 0.6 2.2 2.0 2.6 0.3 1.1 0.2 0.1 1.2 0.9 1.3 0.3 0.0 0.0 1.6 3.2 1.5 0.7 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 13.2 32.1 24.0 22.0 14.8 20.8 33.8 27.4 31.3 18.4 25.9 59.1 8.5 0.0 0.0 17.6 0.4 0.8 2.1 0.0 0.6 10.2 1.1 1.8 10.8 0.0 0.0 1.8 50.1 0.0 0.8 0.2 3.9 2.6 4.7 0.8 3.5 9.3 0.0 0.0 12.0 0.8 0.0 2.2 0.0 1.6 1.3 0.6 8.6 0.1 0.2 6.7 4.8 0.0 0.0 0.6 0.3 5.8 0.6 1.4 3.6 9.4 0.0 3.6 0.0 10.6 232.9 0.7 0.0 0.4 0.0 2.3 0.0 11.7 1.5 43.6 0.0 1.8 2.0 1.7 1.6 0.1 0.1 0.0 0.6 0.7 0.1 0.5 FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 272.0;Alveolar cells type 1: 60.9;Alveolar cells type 2: 69.9;Breast glandular cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 41.3;HUVEC TERT2: 28.0" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" 16.7 4.1 7.7 5.3 8.6 7.2 11.2 16.6 15.5 2.8 0.5 2.8 2.9 3.8 3.8 4.3 2.3 5.1 7.2 6.7 1.7 4.5 4.6 5.1 5.2 1.6 2.3 2.8 2.2 3.9 1.5 10.8 2.9 3.8 2.8 10.5 8.8 2.9 6.0 6.3 3.4 5.1 0.4 5.0 7.3 6.0 3.9 3.2 4.2 5.0 4.1 5.1 2.5 13.7 6.3 2.4 2.5 2.1 12.5 7.1 3.7 5.3 1.2 1.0 1.6 1.9 7.9 41.3 4.9 2.9 3.5 3.1 3.9 5.5 1.8 19.7 6.6 4.4 6.4 3.4 7.4 10.3 2.7 7.8 8.7 1.5 9.1 2.0 28.0 5.8 8.4 19.6 3.1 6.5 3.8 7.4 3.2 10.3 5.9 8.6 4.2 8.5 4.2 6.1 4.6 3.8 5.0 9.0 2.7 3.6 6.5 4.4 17.9 3.2 9.7 2.1 1.9 8.2 11.3 19.1 7.3 5.1 4.1 2.8 0.6 0.6 0.5 0.5 0.4 0.6 0.5 0.4 0.3 0.9 0.5 0.6 1.5 0.6 0.6 1.0 0.6 0.3 7.7 8.6 16.6 15.5 6.7 1.7 1.6 2.3 2.9 0.4 3.9 13.7 272.0 60.9 69.9 0.0 4.9 0.0 0.0 0.0 0.0 0.0 87.0 42.2 0.0 0.0 36.5 33.1 0.0 1.6 9.2 0.0 7.9 12.0 0.0 4.6 3.9 44.0 0.0 0.0 0.0 17.3 2.8 13.8 0.0 12.0 32.8 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 28.2 0.0 0.0 4.0 0.0 0.0 3.5 42.3 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 2.5 9.8 1.3 0.0 0.0 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 119.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 285.7;LHCN-M2: 206.7" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" NA NA 4600000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" 20.1 1.3 14.5 7.2 20.2 0.8 21.9 31.1 12.4 20.0 119.2 35.0 25.9 23.4 16.0 13.3 9.8 23.5 24.8 14.3 27.0 22.1 10.0 12.9 2.4 40.1 42.3 10.4 12.6 11.4 9.7 17.0 24.4 21.4 31.4 3.4 18.7 24.2 3.5 17.5 24.2 25.7 22.1 2.2 16.8 9.7 22.2 6.0 14.6 3.9 4.4 32.0 11.0 22.0 22.2 83.5 80.9 0.3 79.1 94.5 19.9 110.9 181.9 52.8 33.5 50.0 49.0 0.0 26.0 285.7 34.1 40.4 32.0 136.7 71.6 0.2 13.2 0.0 30.5 50.8 39.4 37.3 29.2 34.5 48.4 98.7 63.5 72.4 1.1 44.8 0.6 0.0 206.7 27.1 66.2 0.1 18.1 42.2 13.9 0.3 22.3 1.8 79.2 79.0 8.6 32.3 19.2 32.2 12.7 54.9 0.3 13.3 23.8 149.8 57.9 2.0 69.8 0.4 0.2 0.5 34.1 0.1 52.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 20.2 31.1 12.4 14.3 27.0 40.1 42.3 24.4 22.1 22.2 22.0 6.1 16.0 6.7 55.2 0.3 85.0 27.2 115.4 27.3 5.2 26.5 27.6 27.6 38.6 40.7 53.3 0.0 1.6 0.2 71.2 5.9 25.2 0.7 25.7 17.2 5.0 14.5 0.0 5.8 26.5 3.6 28.8 54.0 29.6 16.5 75.0 1.1 26.1 0.4 0.0 30.3 56.4 18.3 0.8 7.3 0.9 14.6 1.7 12.4 5.6 0.0 4.5 0.0 14.1 12.4 30.3 30.0 37.2 0.2 55.8 78.2 26.7 37.0 0.4 39.5 23.1 65.1 1.5 10.4 10.2 46.9 1.6 1.9 11.7 45.1 38.9 FAT4 "CDHF14, CDHR11, FAT-J" ENSG00000196159 "FAT atypical cadherin 4" Q6V0I7 4 125314918-125492932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 19.3;Endothelial cells: 18.0;Fibroblasts: 17.9;Hepatic stellate cells: 33.2;Inhibitory neurons: 35.0;Microglial cells: 23.4;Oligodendrocytes: 54.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;ASC TERT1: 11.2;fHDF/TERT166: 11.4;HSkMC: 13.6;HUVEC TERT2: 14.3;TIME: 21.9" "Low region specificity" "Detected in many" HPA052819 Approved Approved Cytosol NA NA 2300000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA052819: AB_2681963" "unprognostic (1.18e-1)" "unprognostic (1.77e-1)" "unprognostic (7.99e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (2.81e-4)" "unprognostic (6.17e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.89e-4)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-3)" 3.3 1.0 3.2 1.4 4.1 0.0 2.7 1.2 2.7 4.0 0.7 6.4 0.9 3.0 1.3 2.3 1.9 4.3 4.0 3.8 2.0 2.8 2.5 4.5 0.8 3.1 2.8 4.9 0.9 3.0 0.6 2.9 2.8 3.7 2.3 0.5 1.0 2.6 1.6 1.4 2.2 3.5 3.5 2.7 2.0 0.7 3.3 1.1 4.0 4.8 0.8 2.5 1.8 4.8 0.0 0.9 7.4 0.8 15.5 11.2 0.0 2.6 3.0 1.2 1.2 0.0 0.4 0.0 3.1 11.4 1.5 0.0 2.8 3.2 0.7 0.0 1.3 1.7 3.3 0.1 5.4 1.1 0.0 13.6 1.9 0.7 7.0 9.1 14.3 0.0 0.0 1.9 6.7 0.1 0.5 0.0 0.5 0.0 0.3 0.9 1.5 0.0 0.1 0.0 0.2 1.5 0.4 0.0 0.0 0.4 0.0 0.0 21.9 7.8 2.2 2.7 1.1 0.3 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 4.1 1.2 2.7 3.8 2.0 3.1 2.8 2.8 3.5 3.3 4.8 19.3 6.4 0.0 8.8 0.0 1.7 0.2 1.5 0.0 3.7 0.3 1.3 6.9 0.0 0.3 5.5 0.0 0.1 0.9 0.0 0.0 0.7 0.9 0.6 8.8 18.0 0.0 0.0 9.4 0.2 0.0 17.9 1.1 1.0 0.0 1.2 33.2 7.4 0.2 0.0 35.0 0.0 0.0 2.2 2.2 0.2 5.9 0.3 3.6 23.4 0.0 1.1 1.0 6.0 54.4 0.3 0.0 4.9 1.4 0.4 0.0 0.7 0.1 0.2 0.0 5.3 4.1 0.1 0.6 0.5 0.6 0.0 0.3 5.7 0.0 0.1 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.4;kidney: 297.8;liver: 893.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 500.4;Macrophages: 238.6;Proximal enterocytes: 1095.0;Proximal tubular cells: 864.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 404.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HaCaT: 75.2;MCF7: 243.4;OE19: 54.5;RT4: 157.0;U-698: 170.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" 13.7 27.4 1.6 12.7 1.8 15.0 41.4 1.8 5.7 19.9 2.6 29.8 324.4 3.6 15.8 2.7 7.1 34.4 2.9 1.5 2.2 297.8 893.2 165.9 6.8 3.6 2.6 1.1 41.4 107.9 8.6 3.0 2.9 25.8 30.5 0.7 53.2 28.9 1.3 8.1 258.1 8.8 2.6 12.2 85.6 2.5 3.2 2.2 16.8 0.9 7.8 70.8 6.7 3.8 0.5 0.1 0.3 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.6 3.8 0.0 0.3 0.8 0.1 75.2 0.1 0.0 0.1 0.0 0.3 0.6 2.9 1.3 0.0 1.5 18.8 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.2 0.3 0.2 243.4 0.1 4.4 1.1 54.5 9.5 0.0 0.9 1.9 0.0 157.0 0.7 5.6 0.6 44.5 0.0 0.9 26.7 7.7 0.2 0.1 1.0 0.8 0.0 0.3 1.1 170.4 0.0 1.4 0.1 63.3 68.4 404.3 7.9 162.3 11.7 3.0 4.6 4.6 90.1 3.2 16.2 8.3 12.1 15.4 90.7 32.1 2.3 33.1 1.6 1.8 1.8 5.7 1.5 2.2 3.6 2.6 2.9 2.6 3.2 3.8 2.8 76.9 182.8 0.0 10.3 0.8 8.9 0.7 0.0 0.1 62.4 24.3 0.7 102.9 41.0 62.5 0.0 11.1 14.8 26.1 111.6 21.5 0.1 4.0 0.4 4.8 31.9 24.4 0.9 62.7 1.7 5.4 102.4 5.2 47.4 16.0 12.1 500.4 177.6 0.0 0.8 61.4 0.0 79.9 32.1 1.5 1.5 238.6 12.4 1.9 20.1 2.6 8.2 0.5 0.3 24.0 77.6 4.1 18.3 11.9 1095.0 864.1 9.1 0.2 6.6 0.6 2.0 0.6 1.3 0.8 1.0 10.1 12.1 0.5 90.4 68.1 FBXL7 "FBL6, FBL7, KIAA0840" ENSG00000183580 "F-box and leucine rich repeat protein 7" Q9UJT9 5 15500180-15939795 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 976.2;Inhibitory neurons: 295.1;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 766.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA055464 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055464: AB_2682822" "unprognostic (3.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" "unprognostic (3.34e-1)" "unprognostic (1.50e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.41e-2)" "unprognostic (4.29e-3)" "unprognostic (3.42e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.69e-4)" "unprognostic (1.94e-3)" 17.5 22.7 16.9 3.7 19.5 0.0 13.9 16.0 15.9 19.1 15.9 17.2 2.0 26.4 10.3 9.7 15.8 8.4 17.0 15.5 14.2 4.7 2.1 9.6 2.6 19.7 16.5 26.8 1.9 1.0 4.7 6.6 16.1 13.3 5.2 4.3 5.6 19.5 4.0 5.0 6.8 24.6 15.1 5.0 10.2 4.4 18.4 2.4 8.2 5.7 2.1 16.6 13.1 22.3 0.1 1.4 16.1 23.5 13.1 10.0 0.0 14.1 17.0 9.9 10.3 0.0 0.0 0.0 0.0 21.7 10.2 0.0 8.1 5.2 9.8 0.0 1.1 0.0 0.0 0.0 5.1 0.0 0.0 11.8 0.0 8.0 0.7 12.1 23.2 0.0 0.0 6.1 7.5 0.0 0.0 0.0 5.4 0.0 2.6 0.0 11.4 0.1 0.0 0.0 4.7 15.9 0.0 4.9 15.3 14.5 0.0 0.0 22.9 20.6 4.1 11.7 6.3 0.0 0.0 0.0 11.4 0.0 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 19.5 16.0 15.9 15.5 14.2 19.7 16.5 16.1 15.1 18.4 22.3 21.4 3.2 1.9 976.2 0.3 2.4 2.7 2.4 2.2 3.2 0.9 1.1 11.8 0.0 1.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.4 2.0 11.8 16.7 0.0 0.0 3.7 0.0 0.1 15.9 0.0 2.0 1.3 13.1 15.4 0.2 0.8 30.3 295.1 0.0 0.0 0.6 2.7 0.7 30.1 0.5 5.4 146.1 0.0 2.4 0.0 335.8 766.0 0.0 0.0 41.3 1.2 3.1 0.0 1.2 3.8 2.5 6.6 16.1 8.1 1.4 2.1 1.5 1.7 0.0 0.3 20.7 0.0 2.4 FBXW4 "dactylin, Fbw4, SHFM3" ENSG00000107829 "F-box and WD repeat domain containing 4" P57775 10 101610664-101695295 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043496 Approved Approved "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA043496: AB_2678514" "unprognostic (4.31e-2)" "unprognostic (5.43e-3)" "unprognostic (8.40e-3)" "prognostic favorable (4.91e-4)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (9.96e-3)" "unprognostic (1.87e-1)" "unprognostic (3.96e-1)" "prognostic favorable (4.67e-4)" "unprognostic (1.13e-2)" "prognostic favorable (3.41e-5)" "unprognostic (2.94e-3)" "unprognostic (1.81e-1)" "unprognostic (4.99e-2)" "unprognostic (1.85e-2)" 38.4 30.4 89.9 10.4 96.6 16.0 34.8 83.5 96.3 33.2 71.3 59.9 16.5 26.7 29.6 38.7 28.9 12.9 62.4 80.9 81.1 36.4 34.9 35.8 18.0 92.3 92.1 30.2 44.2 47.0 46.7 16.4 87.8 49.1 16.5 14.2 41.4 26.8 80.0 49.7 31.5 14.7 94.8 30.1 40.8 22.8 94.2 18.1 40.2 44.4 17.9 49.0 32.9 98.0 22.1 25.7 4.0 28.9 20.1 16.5 18.9 11.3 31.1 12.8 10.0 12.0 22.9 25.1 17.5 23.4 13.1 13.4 11.0 16.7 4.3 26.8 15.2 6.0 9.1 26.1 35.7 10.0 7.6 15.2 52.0 6.9 42.8 29.8 11.0 17.6 6.2 15.3 14.2 45.9 11.4 14.2 11.3 11.4 12.3 9.4 29.6 10.7 25.1 14.7 12.3 21.6 21.8 8.1 20.7 6.0 33.6 17.8 11.8 13.8 1.8 5.8 11.5 31.9 15.4 11.1 11.3 12.7 8.1 1.3 1.4 2.2 4.3 0.8 2.6 3.8 4.3 4.2 1.1 4.8 4.5 3.7 0.2 4.2 1.4 4.1 1.4 1.2 89.9 96.6 83.5 96.3 80.9 81.1 92.3 92.1 87.8 94.8 94.2 98.0 13.6 3.2 36.9 45.4 14.0 11.2 16.4 11.9 6.8 28.5 25.7 21.8 35.8 12.8 11.1 11.0 18.8 17.0 24.4 29.1 3.9 15.2 50.2 15.3 16.3 10.0 20.4 7.0 57.5 26.1 9.2 11.3 17.3 27.2 5.1 32.3 8.9 24.7 8.8 37.0 55.7 27.8 14.2 8.6 7.4 28.9 14.3 8.7 14.2 55.3 10.7 29.9 15.5 54.8 70.3 19.4 24.4 17.0 14.1 22.2 21.1 13.3 7.5 22.7 13.1 15.4 14.7 4.9 6.0 11.3 12.5 15.6 16.9 10.9 21.7 18.7 FCGR2B "CD32, CD32B, FCG2, FCGR2" ENSG00000072694 "Fc fragment of IgG receptor IIb" P31994 1 161663147-161678654 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "IgG-binding protein, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "placenta: 398.2" "Cell type enhanced" "Detected in many" "B-cells: 75.0;Hepatic stellate cells: 333.8;Langerhans cells: 244.0;Macrophages: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 327.2;memory B-cell: 202.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 24.9;HMC-1: 31.2;NB-4: 7.3;RPMI-8226: 11.7" "CAB007796, HPA014730" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB007796: AB_562288, HPA014730: AB_2669074" "unprognostic (1.58e-1)" "unprognostic (5.14e-2)" "unprognostic (3.32e-3)" "unprognostic (3.12e-2)" "unprognostic (6.79e-3)" "unprognostic (4.05e-3)" "unprognostic (1.27e-1)" "unprognostic (4.65e-3)" "unprognostic (1.91e-1)" "unprognostic (4.72e-2)" "unprognostic (2.89e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.51e-2)" "unprognostic (6.36e-2)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" 30.4 7.5 0.9 12.2 1.3 1.7 15.4 1.3 3.3 9.7 4.2 10.3 3.0 2.6 2.8 11.4 4.4 13.0 7.9 0.7 1.1 4.2 42.4 21.7 15.8 4.5 1.1 4.8 4.7 2.8 1.4 398.2 2.2 1.8 11.0 1.1 7.0 2.8 2.2 4.8 16.0 16.6 2.2 25.5 4.9 2.5 1.4 7.4 4.2 13.7 29.6 18.7 3.1 5.8 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 7.3 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.8 0.0 327.2 8.5 26.4 1.4 9.7 0.6 202.8 0.7 1.1 72.4 160.4 0.1 1.4 53.6 0.7 9.5 0.1 0.1 13.0 0.9 1.3 1.3 3.3 0.7 1.1 4.5 1.1 2.2 2.2 1.4 5.8 2.2 0.0 3.9 0.0 75.0 5.4 0.1 0.0 0.0 0.0 0.3 0.9 2.1 2.8 1.3 0.0 0.0 0.2 5.6 0.0 0.0 0.0 4.8 0.0 0.0 49.8 0.0 3.2 0.0 0.0 0.2 1.7 1.1 0.0 2.5 0.2 333.8 8.2 7.6 0.0 0.0 0.0 0.0 47.4 244.0 4.2 0.6 145.5 23.2 0.0 9.5 0.0 5.2 0.0 0.1 0.0 0.0 0.0 45.4 0.0 0.0 0.3 0.0 0.0 0.0 1.7 2.5 0.3 0.2 0.7 3.1 0.4 5.8 0.1 0.1 0.0 FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 278.3;lung: 724.6" "Cell type enriched" "Detected in some" 16 "Hepatic stellate cells: 2828.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025945 Approved "Secreted to blood" NA NA 22800000000 14000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" 62.6 35.9 1.1 5.7 1.0 0.0 40.8 1.1 1.6 2.7 10.0 4.1 0.8 3.9 0.1 2.8 3.0 1.6 62.1 1.4 1.1 55.2 278.3 724.6 4.3 1.2 1.2 2.4 12.5 2.7 6.6 22.6 1.2 5.3 0.5 0.0 2.5 0.5 9.0 1.9 6.7 1.8 1.2 11.3 8.4 2.4 1.2 0.4 20.4 7.5 0.3 3.0 1.9 1.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.0 1.1 1.6 1.4 1.1 1.2 1.2 1.2 1.2 1.2 1.0 94.1 0.0 9.3 0.0 16.6 0.8 0.6 0.5 0.6 0.0 0.8 2.8 2.4 52.9 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.5 0.4 0.2 155.1 0.0 136.4 0.1 0.0 0.0 3.8 0.5 0.2 3.8 0.0 2828.6 31.8 0.3 0.0 0.1 0.0 2.0 168.6 0.3 2.7 3.4 2.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.1 5.1 0.0 0.0 1.0 2.7 0.5 0.5 1.0 1.1 0.0 4.9 0.5 0.0 0.3 FEZF2 "FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312" ENSG00000153266 "FEZ family zinc finger 2" Q8TBJ5 3 62369681-62374324 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "brain: 179.0" "Cell type enriched" "Detected in some" 4 "Bipolar cells: 51.5" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in all" 6 "cerebral cortex: 179.0;hippocampal formation: 60.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AF22: 1.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 12.2;cerebral cortex: 12.1;hippocampal formation: 21.3" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (1.70e-1)" 0.1 0.0 13.7 0.0 15.6 0.0 0.0 3.8 179.0 0.0 4.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.1 4.6 0.1 0.0 0.0 0.0 18.9 4.1 0.0 0.0 0.0 0.7 0.0 13.4 0.0 0.0 5.7 0.0 0.0 0.1 0.0 0.0 0.0 5.8 0.1 0.2 0.0 4.8 2.8 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 15.6 3.8 179.0 60.1 4.6 18.9 4.1 13.4 5.8 4.8 21.1 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 51.5 0.9 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.8 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 4.1;lymphoid tissue: 2.5" "Group enriched" "Detected in some" 4 "Gastric mucus-secreting cells: 16.8;Macrophages: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044681: AB_2679043" "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" 4.1 0.1 0.3 2.5 0.5 0.8 2.3 0.3 0.6 0.0 0.5 1.3 0.3 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.4 0.2 0.2 0.4 0.2 1.2 0.5 0.2 0.4 0.1 0.4 0.4 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.4 1.2 0.5 0.1 0.4 0.2 0.6 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.1 0.3 0.5 0.3 0.6 0.5 0.4 1.2 0.5 0.5 0.4 0.4 1.1 1.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 16.8 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 2.6 1.8 0.3 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 FHL5 "ACT, dJ393D12.2, FLJ33049" ENSG00000112214 "Four and a half LIM domains 5" Q5TD97 6 96562548-96616636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 65.5" "Group enriched" "Detected in some" 20 "Early spermatids: 1160.3;Late spermatids: 1540.1" "Cancer enhanced" "Detected in many" "renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "ASC diff: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "prognostic favorable (4.81e-4)" "unprognostic (4.93e-2)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.84e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-3)" "unprognostic (1.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.22e-1)" "unprognostic (3.48e-3)" 35.7 10.3 5.4 4.4 8.5 0.0 16.0 5.8 7.5 27.8 6.2 5.8 2.5 15.0 17.6 9.6 21.5 12.9 5.6 4.9 5.3 6.4 0.4 14.0 1.8 6.3 5.8 11.4 4.6 3.3 1.2 0.6 7.1 4.9 5.0 0.4 2.1 11.1 8.9 5.5 5.1 9.6 5.4 3.5 4.0 65.5 7.2 1.2 8.9 14.6 0.8 6.8 10.3 5.5 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 8.5 5.8 7.5 4.9 5.3 6.3 5.8 7.1 5.4 7.2 5.5 5.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1160.3 0.0 0.1 3.8 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1540.1 52.5 1.1 5.4 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.2 0.0 0.0 0.0 0.0 52.6 1.9 67.4 13.2 4.4 0.0 0.3 0.0 0.6 0.1 0.0 0.2 FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 79.1;Fibroblasts: 100.0;Sertoli cells: 59.2;Smooth muscle cells: 65.3;Theca cells: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051171, HPA057021" Enhanced Approved Mitochondria "Intracellular and membrane" NA NA 110000 "Cluster 22: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" 39.4 39.5 20.9 27.1 22.2 0.5 33.5 21.7 26.1 64.0 22.0 29.1 7.6 61.5 16.9 13.9 50.9 46.0 45.6 20.3 22.1 17.7 7.8 37.8 10.9 24.6 21.6 58.4 15.1 48.5 56.7 60.7 22.2 32.6 10.8 6.0 14.7 30.8 7.6 20.4 19.1 55.6 21.9 14.3 18.5 9.0 24.2 4.9 34.9 9.3 4.4 42.2 39.1 21.6 0.7 119.6 110.7 363.3 379.3 441.7 92.0 490.4 497.4 185.6 159.0 62.1 4.8 0.3 6.6 551.9 45.9 0.8 66.7 133.4 77.9 33.0 99.9 48.6 132.1 181.0 411.4 0.0 0.6 476.1 0.5 150.3 115.5 352.6 158.8 0.0 1.9 16.7 157.0 163.2 0.3 0.1 85.4 258.0 38.3 9.9 125.2 15.7 31.7 0.1 26.7 92.1 0.7 349.3 166.0 137.4 54.1 3.1 181.0 219.0 111.5 145.8 76.0 0.8 0.2 0.3 299.7 0.0 213.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.9 22.2 21.7 26.1 20.3 22.1 24.6 21.6 22.2 21.9 24.2 21.6 14.9 0.0 4.8 38.2 0.2 8.5 11.5 2.7 1.2 0.6 10.8 13.2 2.3 1.5 1.4 0.0 0.0 6.1 0.2 0.1 0.0 8.7 0.7 3.0 79.1 34.9 0.0 0.0 0.3 4.7 30.8 100.0 1.5 4.6 0.0 32.9 30.4 0.0 4.7 15.2 0.3 1.3 0.0 0.0 9.7 2.9 46.9 1.5 16.0 15.0 0.0 32.0 0.0 17.1 0.1 2.2 0.1 44.8 0.5 8.2 0.0 0.0 0.1 1.1 59.2 35.2 65.3 0.9 7.6 0.5 5.1 11.9 2.1 54.0 0.6 1.6 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 683.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 64.2;Cholangiocytes: 133.0;Hepatocytes: 265.4;Proximal enterocytes: 108.8;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "Hep G2: 41.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" 3.1 5.7 2.0 5.1 2.9 2.0 46.1 3.9 2.8 7.8 0.5 41.3 71.3 2.8 6.9 1.2 3.6 15.8 3.1 2.1 2.4 51.5 683.3 27.1 4.0 4.2 2.9 4.1 48.1 68.3 6.7 2.4 4.8 9.7 46.6 0.9 32.7 4.0 0.8 11.6 73.9 3.5 3.2 4.0 120.1 5.2 3.1 1.1 2.0 1.4 2.5 3.9 1.5 5.6 0.1 1.1 0.6 0.1 2.8 0.8 0.9 0.7 0.5 0.3 0.8 0.7 2.4 0.4 0.8 0.8 0.2 0.4 0.0 0.0 0.0 1.4 0.2 1.6 0.1 41.7 0.9 1.4 9.0 1.3 0.2 0.4 0.0 0.4 0.6 0.2 0.1 0.1 1.5 1.4 0.2 0.7 2.8 5.3 0.8 0.4 0.5 0.4 3.4 0.6 0.5 0.3 0.9 2.8 1.3 1.3 2.1 10.4 1.1 0.0 0.3 0.9 0.0 0.3 0.0 0.3 1.1 0.5 0.3 7.0 12.9 4.1 2.0 5.9 0.3 4.7 0.5 0.6 5.4 8.5 0.3 1.3 1.3 1.2 1.8 2.5 1.6 3.9 2.0 2.9 3.9 2.8 2.1 2.4 4.2 2.9 4.8 3.2 3.1 5.6 2.8 9.6 64.2 11.1 6.4 1.7 3.9 0.9 1.8 2.0 17.5 6.7 1.9 133.0 10.4 14.7 0.0 1.5 1.7 60.8 7.9 7.5 7.7 2.5 1.8 2.7 6.7 4.8 8.2 5.9 1.1 2.9 24.5 6.1 5.7 9.8 5.0 265.4 4.0 3.3 6.4 34.4 4.1 10.0 2.3 4.5 2.8 4.6 28.4 10.3 5.3 0.2 4.1 10.1 17.5 7.0 29.0 1.5 0.4 5.6 108.8 69.2 18.1 1.3 0.0 2.2 1.0 5.9 0.9 1.3 1.6 1.4 2.6 6.6 20.7 6.4 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 FRMPD2 "MGC35285, PDZD5C, PDZK5C" ENSG00000170324 "FERM and PDZ domain containing 2" Q68DX3 10 48153088-48274696 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;choroid plexus: 5.2;retina: 24.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 50.0;Cone photoreceptor cells: 287.7;Early spermatids: 97.7;Endometrial ciliated cells: 70.6;Late spermatids: 118.5;Respiratory ciliated cells: 62.9;Rod photoreceptor cells: 90.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;HBEC3-KT: 1.0;SCLC-21H: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "unprognostic (1.53e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-4)" "unprognostic (7.59e-2)" "unprognostic (2.37e-1)" "unprognostic (2.06e-1)" "unprognostic (6.54e-3)" "unprognostic (1.85e-1)" "unprognostic (6.60e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-12)" "unprognostic (3.48e-2)" "unprognostic (5.43e-2)" "unprognostic (1.54e-1)" "unprognostic (7.43e-5)" 0.0 0.0 2.4 0.0 2.0 0.0 0.4 2.7 1.3 0.2 5.2 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.9 2.1 2.7 0.1 0.0 0.2 0.0 4.7 6.7 0.0 0.0 0.0 0.1 0.0 4.1 0.3 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.3 3.5 0.0 0.5 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.3 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.0 2.7 1.3 2.1 2.7 4.7 6.7 4.1 4.0 3.5 3.4 0.0 0.0 0.5 36.6 0.0 0.1 0.4 1.6 0.0 50.0 1.1 0.4 5.0 0.0 4.6 3.7 287.7 0.2 0.0 0.1 0.0 0.1 97.7 70.6 0.5 0.3 3.0 0.0 2.0 0.0 0.3 0.8 0.0 1.6 0.0 0.0 0.0 0.2 0.1 3.3 0.9 0.6 6.1 0.0 0.0 118.5 0.3 0.2 0.0 0.0 0.0 5.2 0.0 0.5 0.3 0.2 0.1 0.4 0.0 0.4 4.2 0.5 62.9 90.8 0.0 0.2 0.6 2.1 1.0 0.0 0.3 0.0 0.1 0.1 0.7 0.4 FSIP1 FLJ35989 ENSG00000150667 "Fibrous sheath interacting protein 1" Q8NA03 15 39588357-39782841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 10.9;testis: 7.2" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Excitatory neurons: 28.2;Inhibitory neurons: 21.5;Late spermatids: 48.3;Spermatocytes: 35.3" "Cancer enriched" "Detected in some" 8 "breast cancer: 6.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 4.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA041002 Uncertain Uncertain Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA041002: AB_10796565" "unprognostic (1.55e-2)" "unprognostic (1.49e-1)" "unprognostic (9.12e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.43e-3)" "unprognostic (5.17e-3)" "unprognostic (5.37e-2)" "unprognostic (9.22e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (1.14e-1)" "unprognostic (3.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.81e-1)" 0.2 0.2 1.6 0.2 1.8 0.6 0.9 0.0 1.6 0.2 1.7 7.3 0.1 0.3 0.3 0.1 1.2 0.2 0.2 1.2 1.8 0.8 0.1 0.2 0.1 1.1 1.3 0.1 0.1 0.8 1.4 0.3 0.9 0.2 10.9 0.9 0.1 0.2 0.2 0.9 0.1 0.3 0.3 0.2 0.5 7.2 2.0 1.4 0.4 0.1 0.1 0.3 0.1 0.4 0.4 1.3 3.4 0.5 0.6 1.1 0.0 4.1 0.8 0.6 1.2 1.0 0.3 0.2 0.3 1.2 1.7 0.8 0.5 0.7 1.0 1.4 0.3 2.5 0.9 0.0 0.3 0.5 2.7 0.7 2.8 1.5 0.6 0.8 0.7 1.4 0.1 0.3 1.0 0.1 0.3 0.2 0.4 0.2 0.6 0.3 0.7 0.1 1.3 1.5 0.8 2.5 0.8 0.1 0.1 0.3 1.1 0.3 0.6 1.6 0.9 0.9 0.4 0.7 1.6 0.2 3.3 0.9 0.8 0.4 0.3 0.4 0.7 0.2 0.5 0.1 0.3 0.4 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 1.6 1.8 0.0 1.6 1.2 1.8 1.1 1.3 0.9 0.3 2.0 0.4 0.7 0.0 0.5 8.1 1.1 0.6 0.6 3.4 0.0 1.1 14.5 7.9 0.8 2.8 2.9 1.8 12.5 0.9 1.4 17.5 1.9 1.0 67.1 10.0 2.1 1.0 0.0 0.0 28.2 0.4 0.1 1.5 0.5 0.6 15.8 0.4 0.4 0.0 0.1 0.0 21.5 3.5 0.0 0.0 0.3 48.3 1.2 0.6 0.0 7.5 0.1 1.0 3.1 3.0 3.2 0.1 6.6 0.7 0.4 0.7 0.0 3.2 12.6 6.1 0.0 1.2 1.5 35.3 8.3 0.2 0.0 5.6 3.3 0.7 2.9 0.3 FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 305.6;salivary gland: 220.5" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 117.5;Hepatocytes: 131.8;Pancreatic endocrine cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" NA NA 130000 "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" 54.5 24.4 12.8 36.4 10.5 73.8 42.4 10.6 14.5 26.4 11.7 32.8 27.6 32.3 9.8 33.7 30.4 19.4 58.5 14.9 9.0 56.8 305.6 63.2 13.0 12.5 10.8 22.4 108.6 27.3 45.9 40.6 11.3 60.1 12.1 12.9 220.5 17.7 61.3 62.7 35.5 14.3 10.4 51.4 34.0 8.6 15.6 11.8 56.1 25.3 11.2 30.2 33.3 9.3 50.8 31.2 6.8 29.8 49.4 32.1 77.5 64.4 48.1 26.3 18.1 45.4 54.3 1.9 148.8 47.5 46.1 91.5 14.0 32.5 5.4 148.0 35.2 90.9 52.8 57.7 26.2 13.0 141.2 35.6 35.3 29.5 13.2 62.4 84.7 14.6 70.5 8.5 17.8 32.3 5.0 29.2 21.5 44.2 9.3 7.9 26.6 10.9 35.2 39.1 13.1 9.2 54.5 28.5 42.5 31.9 10.7 31.4 125.9 29.4 60.1 43.7 95.5 15.2 93.4 3.4 55.8 40.1 60.7 2.0 0.9 1.5 0.7 0.1 0.2 0.4 0.2 0.3 0.6 0.1 0.0 0.1 0.7 0.4 0.0 0.3 0.0 1.1 12.8 10.5 10.6 14.5 14.9 9.0 12.5 10.8 11.3 10.4 15.6 9.3 44.1 3.2 27.4 4.2 7.3 19.4 10.0 10.4 2.8 12.8 12.0 9.0 16.3 21.5 8.5 22.0 25.0 20.9 26.9 49.5 0.0 47.1 0.5 15.2 9.7 29.4 37.8 26.5 7.9 117.5 16.5 11.4 21.9 32.3 15.8 7.0 23.9 131.8 24.8 8.4 7.5 31.7 10.2 35.3 42.1 1.4 11.1 33.6 16.0 5.6 14.0 13.6 24.7 2.0 4.4 108.3 26.4 10.9 7.2 24.3 28.7 7.8 2.0 28.0 26.3 10.5 18.6 2.8 3.6 8.5 23.0 84.3 19.6 4.7 17.9 16.4 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 382.6;dendritic cells: 291.6;NK-cells: 228.6;Oligodendrocyte precursor cells: 342.8;Proximal tubular cells: 212.2;T-cells: 275.8" "Cancer enhanced" "Detected in all" "glioma: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 16 "NK-cells: 69.0;T-cells: 174.8" "Cell line enhanced" "Detected in many" "U-2197: 538.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" NA NA 820000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: AB_2685119" "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favorable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 76.6 10.8 117.1 52.4 106.4 32.3 46.8 83.8 104.3 45.5 33.3 32.9 16.4 45.6 33.8 16.0 51.4 32.1 40.5 102.1 121.5 23.9 20.4 63.5 108.9 136.3 104.9 28.8 8.5 18.7 22.9 29.7 107.0 17.6 15.6 26.9 12.9 12.5 12.3 41.5 47.1 38.0 109.9 71.9 29.3 16.5 105.7 86.1 45.7 18.3 67.6 48.4 33.4 109.8 10.4 1.5 178.6 30.2 133.4 81.4 3.2 29.1 90.8 24.2 42.9 1.3 1.6 21.0 18.3 56.1 21.0 1.3 25.8 39.9 46.8 0.7 66.5 57.0 13.6 2.7 78.7 19.5 19.0 78.8 59.1 90.5 76.8 62.9 99.5 99.6 4.9 140.3 86.8 1.5 92.7 17.9 26.0 3.3 18.0 29.1 24.0 1.4 0.0 9.1 124.6 50.7 5.7 2.4 124.7 39.6 1.3 57.0 63.9 72.3 13.5 538.7 18.5 20.0 19.7 32.5 136.0 44.3 128.9 1.1 6.4 0.2 137.0 5.6 174.8 4.8 83.9 152.7 7.4 6.4 27.9 72.3 3.0 69.0 4.2 4.3 79.2 51.5 117.1 106.4 83.8 104.3 102.1 121.5 136.3 104.9 107.0 109.9 105.7 109.8 87.8 0.0 8.3 382.6 26.0 17.1 2.5 0.6 1.8 57.2 2.9 6.9 11.3 14.3 2.1 7.3 0.0 2.7 291.6 1.2 17.6 9.3 3.7 5.6 51.7 70.3 13.2 20.9 118.7 1.0 2.4 61.9 17.9 4.9 52.0 20.9 76.4 60.3 3.0 47.1 127.6 3.8 2.0 35.8 96.1 3.2 26.4 42.7 37.4 88.1 64.5 89.1 228.6 342.8 162.3 9.7 0.1 7.2 96.2 3.9 17.7 212.2 4.4 8.3 13.1 48.8 32.9 3.9 8.6 0.7 13.4 52.0 275.8 71.1 2.9 1.1 GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 68.4;Kupffer cells: 72.1;Late spermatids: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 84.3;HMC-1: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" NA NA 53000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" 15.0 17.2 20.0 14.9 23.3 23.2 13.3 22.1 26.1 12.0 20.8 15.1 33.3 11.1 12.2 6.6 20.7 18.4 13.5 18.5 21.6 21.3 12.1 23.9 11.7 23.0 22.6 15.8 10.8 9.4 9.8 16.8 23.9 14.3 17.3 18.4 8.1 9.3 8.0 9.1 34.4 9.6 22.3 15.4 16.4 24.0 20.8 9.7 24.5 12.9 7.9 13.6 7.5 30.6 0.0 19.5 7.2 0.0 23.8 21.3 0.0 9.1 17.9 8.3 9.9 10.8 84.3 5.3 26.4 8.7 0.0 1.3 0.0 1.0 10.2 2.7 0.6 29.8 0.7 0.0 19.5 0.1 78.4 20.7 6.6 5.6 0.0 3.4 22.6 0.0 10.0 3.9 14.4 1.9 0.0 4.5 6.5 35.4 2.2 0.0 0.5 0.3 13.4 7.8 6.7 15.6 24.6 4.0 0.2 17.2 20.4 20.5 19.7 0.0 12.9 5.6 0.2 4.2 8.0 0.0 2.3 6.8 19.2 25.3 15.2 34.2 11.1 16.6 24.0 2.5 8.3 10.8 8.9 1.2 6.0 7.0 11.9 16.3 13.4 1.6 5.3 11.7 20.0 23.3 22.1 26.1 18.5 21.6 23.0 22.6 23.9 22.3 20.8 30.6 11.3 25.6 19.0 26.8 8.0 8.4 5.6 9.4 3.4 10.1 9.1 5.2 9.2 10.0 8.9 14.7 12.5 6.2 27.6 15.3 3.9 9.8 51.6 17.3 10.9 11.4 6.1 13.7 17.8 11.4 12.7 15.2 7.7 5.8 68.4 15.9 18.2 6.1 26.6 3.3 21.2 10.2 4.1 72.1 11.8 77.9 16.1 25.0 10.6 8.4 26.7 7.3 40.2 33.2 42.6 14.1 20.0 10.1 9.3 6.1 15.9 6.7 22.1 10.4 0.0 9.8 10.6 14.9 10.0 3.5 11.5 6.6 21.2 12.9 16.7 7.9 GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 429.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 13000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavorable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" 32.9 49.6 17.0 34.8 19.9 13.9 21.9 15.2 16.7 24.7 22.0 28.9 19.5 27.1 6.9 21.0 22.4 21.2 27.4 15.8 18.6 18.5 100.1 27.1 14.0 23.0 19.5 39.2 68.1 9.9 13.6 27.6 18.3 21.4 12.4 19.8 22.1 14.3 67.4 14.7 23.6 25.0 15.3 17.4 33.1 19.7 25.1 42.8 19.0 27.4 11.2 33.4 19.5 15.5 79.5 103.7 59.9 71.4 112.4 95.3 122.8 146.3 90.0 58.4 55.6 45.2 146.5 20.0 106.2 77.7 135.9 150.7 39.9 123.0 48.6 200.1 52.0 60.7 217.2 50.9 60.9 23.4 114.8 136.9 59.8 78.0 30.9 127.3 69.2 110.1 77.0 29.6 65.6 21.8 122.3 23.9 82.1 52.8 97.7 134.3 85.5 61.7 57.4 92.9 18.9 70.1 148.4 7.9 91.0 31.7 46.5 43.5 165.3 56.7 107.9 129.5 118.0 97.9 60.3 44.4 146.1 46.3 429.7 1.5 10.7 3.6 4.4 9.3 3.2 3.4 2.6 4.5 7.8 5.8 2.5 5.0 3.2 2.8 10.2 13.2 3.3 7.7 17.0 19.9 15.2 16.7 15.8 18.6 23.0 19.5 18.3 15.3 25.1 15.5 18.6 16.0 21.3 71.5 32.1 15.3 20.0 52.8 20.5 30.8 13.8 10.7 13.6 18.6 30.1 23.9 33.3 7.3 21.7 24.1 5.9 49.7 47.2 18.7 15.4 17.9 16.8 27.6 67.3 133.0 123.4 36.1 21.4 24.5 13.3 20.5 19.6 98.8 24.9 28.6 82.0 18.9 4.1 42.4 9.7 24.6 35.8 28.9 24.9 106.8 44.0 10.9 18.6 72.9 44.6 88.5 21.6 29.3 109.0 23.5 17.9 19.2 23.5 73.5 13.1 33.1 25.4 3.4 14.0 16.6 8.0 16.6 21.2 32.8 17.6 29.9 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 348.3;Sertoli cells: 322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.7" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.7" "Cell line enhanced" "Detected in many" "BJ: 347.0;BJ hTERT+: 494.0;HSkMC: 281.3;RPMI-8226: 493.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" NA NA 8900000 3600000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" 124.2 32.5 26.7 18.8 28.7 3.6 77.4 33.9 32.0 244.4 59.3 67.8 48.7 171.7 13.8 63.2 161.3 58.9 169.1 24.1 34.6 72.7 37.1 97.3 22.5 37.4 36.1 118.0 49.9 58.5 58.4 51.6 38.5 100.9 25.2 6.3 84.4 63.8 99.2 101.4 47.8 57.9 30.8 29.4 70.0 60.1 34.1 39.6 101.2 67.5 10.6 127.0 172.0 25.2 151.3 6.6 4.4 3.8 169.5 94.0 18.4 347.0 494.0 141.3 168.4 9.6 71.0 1.4 11.4 157.2 24.9 139.1 2.4 77.7 35.6 0.2 20.1 1.1 11.1 1.0 120.8 1.0 2.1 281.3 44.9 39.1 39.0 243.2 5.3 2.3 2.6 79.9 231.9 7.4 0.8 1.5 9.5 24.0 9.9 4.5 0.1 493.5 51.9 1.9 23.5 21.3 38.3 1.3 0.4 23.8 45.9 119.4 81.7 36.9 45.0 4.4 100.5 0.1 8.0 1.5 41.9 3.6 5.8 0.0 1.4 0.0 0.0 1.1 0.0 0.1 0.2 0.0 11.3 0.1 0.0 0.0 0.0 0.1 0.3 70.7 0.0 1.4 26.7 28.7 33.9 32.0 24.1 34.6 37.4 36.1 38.5 30.8 34.1 25.2 133.2 198.7 25.9 23.2 20.8 84.4 94.7 18.5 70.0 38.0 17.9 114.3 86.8 50.1 23.4 31.3 0.0 1.8 59.1 92.4 27.4 45.7 5.1 35.2 33.1 71.9 10.3 5.3 26.2 6.7 1.9 152.7 19.9 32.3 8.2 154.7 159.9 21.6 101.6 348.3 31.9 69.5 8.2 22.3 100.4 8.9 92.2 48.6 122.7 41.2 9.8 32.7 0.0 3.0 7.5 24.1 58.6 59.5 147.4 30.5 84.1 0.6 15.5 12.5 322.1 22.9 121.1 5.3 17.6 27.6 71.9 2.9 4.7 214.8 151.4 31.1 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 447.4" "Cancer enhanced" "Detected in all" "urothelial cancer: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.4" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 32.1;MCF7: 50.6;OE19: 53.3;SK-BR-3: 165.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: AB_10794545, HPA041470: AB_10795121" "unprognostic (4.12e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (9.99e-2)" "unprognostic (2.53e-1)" "unprognostic (4.57e-3)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (4.53e-1)" "unprognostic (8.86e-3)" "unprognostic (6.59e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.89e-9)" "unprognostic (3.11e-1)" "unprognostic (3.13e-1)" "unprognostic (1.12e-1)" "unprognostic (8.79e-3)" 7.1 2.4 6.1 6.0 6.1 1.8 5.4 6.8 11.4 18.7 5.9 25.9 8.4 5.3 9.3 45.6 5.7 2.5 5.2 6.0 6.1 17.9 2.1 6.4 4.2 7.5 6.1 6.8 2.2 0.4 4.8 11.4 8.0 5.7 17.2 6.5 9.0 2.2 2.1 11.0 10.2 5.2 6.3 9.0 18.8 1.8 6.1 4.1 4.7 0.9 20.9 5.4 19.1 6.8 21.8 0.3 5.2 1.5 1.6 5.5 5.5 0.6 1.3 1.8 1.7 1.0 15.2 0.6 2.9 1.5 0.6 1.8 1.6 0.5 1.8 2.5 4.0 0.2 1.0 32.1 1.0 0.7 1.3 0.2 1.6 4.5 0.3 4.1 5.1 4.2 1.0 2.3 2.2 50.6 1.5 2.0 2.6 53.3 0.6 6.3 1.4 7.1 2.6 7.4 1.1 2.2 0.2 165.0 0.5 1.6 3.0 2.7 2.7 0.9 1.1 1.9 1.8 2.7 0.9 1.5 4.2 2.7 0.7 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 0.0 6.1 6.1 6.8 11.4 6.0 6.1 7.5 6.1 8.0 6.3 6.1 6.8 5.9 6.4 1.1 1.6 1.0 1.3 0.9 4.4 1.2 1.6 4.1 3.0 1.5 0.0 22.2 5.5 0.0 24.2 1.2 98.2 5.9 0.9 67.8 2.6 3.8 4.3 3.5 0.0 0.6 1.3 71.9 2.1 30.1 4.1 0.0 2.0 3.9 0.3 3.1 1.7 0.8 34.2 6.1 1.9 1.0 447.4 3.4 1.4 1.8 1.9 1.2 0.6 0.0 1.5 1.2 19.2 36.7 3.0 0.1 1.1 46.0 100.6 9.0 1.7 6.6 0.6 2.7 1.4 1.3 5.1 2.0 9.3 1.9 1.3 13.9 4.8 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIMAP8 "DKFZp667I133, hIAN6, IAN9" ENSG00000171115 "GTPase, IMAP family member 8" Q8ND71 7 150450630-150479393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.6" "Cell type enhanced" "Detected in many" "Adipocytes: 67.4;Endothelial cells: 66.0;Hepatic stellate cells: 86.0;Kupffer cells: 75.1;Microglial cells: 32.8;monocytes: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "HUVEC TERT2: 59.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014474, HPA017765" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA014474: AB_1849685, HPA017765: AB_1849683" "unprognostic (7.86e-2)" "unprognostic (7.87e-3)" "unprognostic (1.04e-1)" "unprognostic (4.42e-3)" "unprognostic (2.11e-1)" "unprognostic (8.09e-3)" "unprognostic (1.07e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (8.07e-2)" "unprognostic (6.26e-3)" "unprognostic (2.15e-1)" "unprognostic (1.04e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" 20.3 5.7 4.4 21.3 5.0 0.7 16.0 4.7 5.5 9.8 5.5 6.7 6.8 10.4 3.1 4.3 9.0 7.5 17.4 4.1 4.5 8.3 9.4 27.0 23.2 5.4 4.9 3.5 2.8 4.6 2.6 15.4 5.4 4.9 7.2 0.3 4.3 5.3 9.8 4.7 10.5 12.7 5.4 40.6 5.0 2.0 5.1 7.3 11.9 15.1 13.5 8.4 5.6 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.0 59.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.7 0.0 9.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.5 45.2 0.0 15.3 59.0 17.4 0.5 14.8 13.9 13.0 0.0 16.7 13.6 4.8 15.5 57.4 0.7 7.7 26.8 4.4 5.0 4.7 5.5 4.1 4.5 5.4 4.9 5.4 5.4 5.1 5.8 67.4 3.2 5.3 0.3 0.8 3.1 0.5 0.0 1.8 0.0 0.4 0.8 5.5 5.7 0.0 1.8 0.0 0.0 5.3 0.0 0.0 0.0 0.3 0.2 0.1 66.0 0.0 1.3 0.1 0.0 0.0 2.3 0.5 0.2 3.8 0.0 86.0 1.6 6.8 0.0 0.1 0.0 0.0 75.1 2.8 0.9 0.3 21.9 0.0 32.8 44.2 0.0 19.6 0.0 0.1 0.0 0.0 0.0 2.2 0.9 0.0 0.2 1.5 0.0 0.0 1.5 1.2 0.2 0.4 0.5 1.7 0.1 11.1 0.2 0.0 0.4 GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.0;kidney: 41.4;lymphoid tissue: 27.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 122.1;Proximal tubular cells: 267.7;Undifferentiated cells: 63.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.1;HaCaT: 6.0;Hep G2: 23.0;HUVEC TERT2: 23.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" 3.9 23.8 0.5 1.7 0.4 0.3 3.0 0.4 0.5 1.8 0.5 15.6 38.0 2.1 0.9 2.1 3.1 5.5 1.5 0.5 0.4 41.4 18.4 2.7 0.8 0.4 0.4 2.4 18.1 2.3 0.9 3.5 0.4 1.7 14.9 0.1 4.2 0.9 1.1 4.7 38.0 2.8 0.4 27.9 6.0 1.0 0.5 0.4 1.0 1.6 0.8 2.0 1.9 0.4 0.0 0.0 0.0 0.1 2.4 6.1 0.0 1.0 0.0 0.5 1.1 5.1 3.3 1.5 0.1 0.5 0.0 6.0 0.0 0.0 3.2 0.2 0.0 0.8 0.0 23.0 1.2 0.0 0.0 1.0 0.1 3.5 0.1 0.0 23.5 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.5 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.4 33.6 0.0 1.3 2.0 2.0 12.9 2.4 0.9 4.0 0.4 5.2 1.5 3.2 27.1 2.5 9.2 2.1 6.7 0.0 43.7 33.2 11.8 2.5 13.3 0.9 21.6 3.0 0.4 14.7 33.0 3.1 2.9 8.6 7.2 0.0 5.9 22.9 43.3 13.2 0.0 15.2 34.4 0.0 0.8 1.9 1.2 1.2 2.1 0.0 14.0 1.0 0.0 0.0 4.5 8.9 16.5 39.3 0.0 0.0 0.8 122.1 267.7 11.7 0.5 0.0 1.3 1.3 0.6 2.5 7.9 21.7 1.6 1.3 32.4 63.8 6.0 GJC3 "CX30.2, GJE1" ENSG00000176402 "Gap junction protein gamma 3" Q8NFK1 7 99923266-99929620 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 8.7;pancreas: 11.1;salivary gland: 11.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.3;Breast myoepithelial cells: 26.9;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 12.8;Prostatic glandular cells: 13.0" "Group enriched" "Detected in many" 5 "breast cancer: 3.8;melanoma: 3.0;prostate cancer: 3.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 1.3;SK-MEL-30: 2.3;U-2197: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015024 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" "HPA015024: AB_1847132" "unprognostic (9.31e-2)" "unprognostic (6.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-2)" "unprognostic (2.54e-1)" "unprognostic (2.88e-2)" "unprognostic (7.68e-2)" "unprognostic (9.14e-2)" "unprognostic (6.71e-2)" "unprognostic (4.78e-2)" "unprognostic (1.20e-1)" "unprognostic (3.88e-3)" "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (3.49e-1)" "unprognostic (5.81e-3)" 1.6 0.5 0.8 0.1 0.9 0.1 8.7 0.1 1.2 0.3 0.0 0.5 0.4 0.2 0.0 0.2 0.3 0.3 0.4 0.9 0.3 1.0 2.7 0.2 0.2 0.2 0.4 0.4 11.1 0.0 0.4 1.0 0.2 4.6 0.0 1.0 11.7 0.1 0.2 2.6 0.3 0.2 0.0 0.3 1.4 1.7 0.6 0.1 0.3 0.2 0.0 0.3 0.3 0.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.5 0.6 0.1 0.5 0.2 0.4 1.1 1.3 0.0 0.0 0.4 0.3 0.0 0.4 0.1 0.2 0.1 0.3 2.3 0.5 0.7 0.0 0.3 0.1 0.4 1.8 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.9 0.1 1.2 0.9 0.3 0.2 0.4 0.2 0.0 0.6 0.5 1.1 3.2 3.7 0.0 0.4 0.3 4.9 1.4 0.0 0.0 36.3 26.9 0.0 4.3 2.1 1.8 0.0 0.0 0.6 0.0 1.9 0.4 0.4 0.0 0.0 1.5 1.2 0.0 0.7 24.0 0.0 0.2 0.0 0.0 4.5 0.2 1.1 5.0 0.1 0.0 0.4 0.1 8.2 0.0 0.3 1.1 0.3 0.1 0.0 0.0 0.6 4.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 13.0 0.0 9.7 0.3 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 9.4 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLDC "GCSP, NKH" ENSG00000178445 "Glycine decarboxylase" P23378 9 6532467-6645729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 173.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.3;Cytotrophoblasts: 79.0;Extravillous trophoblasts: 41.6;Hepatocytes: 120.5;Oligodendrocyte precursor cells: 52.3;Proximal tubular cells: 31.6;Syncytiotrophoblasts: 46.0" "Cancer enhanced" "Detected in many" "testis cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 235.7;CACO-2: 58.2;HMC-1: 45.6;RPTEC TERT1: 95.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002318, HPA052887" Enhanced Supported Nucleoplasm,Mitochondria NA NA 740000 "Cluster 37: B-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Nucleoplasm "HPA002318: AB_1849700, HPA052887: AB_2681980" "unprognostic (6.73e-2)" "unprognostic (1.19e-1)" "unprognostic (6.50e-2)" "prognostic unfavorable (5.24e-5)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (1.81e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.74e-1)" "unprognostic (2.47e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.65e-2)" "unprognostic (1.27e-1)" "unprognostic (5.62e-3)" "unprognostic (1.17e-2)" 0.3 0.3 15.3 1.4 15.5 0.5 0.8 14.7 23.7 0.4 12.9 1.0 0.8 0.4 5.2 3.2 0.7 0.8 0.1 14.8 14.4 38.2 173.5 1.0 1.6 14.0 13.6 0.3 0.1 0.0 4.9 15.2 13.4 0.5 0.4 1.6 1.1 1.0 1.3 4.5 0.8 0.0 13.1 1.2 1.0 3.5 15.8 0.0 5.1 0.1 1.2 1.1 0.1 15.3 0.6 4.9 2.1 25.6 0.2 0.4 235.7 0.1 0.0 0.0 0.1 58.2 0.5 0.3 5.6 0.1 0.7 0.4 0.0 0.7 0.2 1.2 13.4 0.2 0.3 38.3 0.0 0.1 45.6 0.0 0.1 1.8 0.3 1.0 9.0 4.3 0.0 0.5 1.2 1.5 0.9 0.2 27.5 4.6 3.8 1.3 0.0 0.5 95.4 1.0 22.6 11.7 0.0 21.4 0.3 13.9 5.3 0.1 3.0 0.6 0.6 2.6 1.3 1.1 34.4 0.1 0.8 2.4 5.1 0.4 0.1 0.1 0.1 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.0 0.3 15.3 15.5 14.7 23.7 14.8 14.4 14.0 13.6 13.4 13.1 15.8 15.3 0.2 0.0 0.0 17.6 1.9 0.0 0.0 0.2 1.2 0.4 1.5 0.6 0.7 11.5 0.1 31.3 0.0 79.0 0.2 0.0 5.9 0.0 12.6 5.4 0.5 0.6 0.0 0.0 21.6 0.2 41.6 0.3 0.0 10.7 0.0 1.1 2.2 120.5 7.0 0.0 15.9 0.0 0.0 2.8 0.3 10.8 0.3 0.4 0.0 1.9 0.0 9.6 0.0 52.3 1.8 0.1 0.0 0.0 15.1 0.0 0.0 31.6 0.0 0.4 0.0 1.7 0.8 4.5 5.1 0.4 0.0 46.0 0.8 0.0 0.0 0.1 GLG1 "CFR-1, ESL-1, MG-160" ENSG00000090863 "Golgi glycoprotein 1" Q92896 16 74447427-74607144 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010815 Supported Supported "Golgi apparatus" NA NA 2100000 "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "HPA010815: AB_2232486" "unprognostic (3.70e-2)" "prognostic unfavorable (1.99e-4)" "unprognostic (7.42e-2)" "unprognostic (3.30e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-3)" "unprognostic (5.13e-3)" "unprognostic (9.45e-3)" "unprognostic (8.46e-2)" "unprognostic (1.61e-1)" "unprognostic (1.29e-1)" "unprognostic (8.85e-2)" "prognostic favorable (1.56e-7)" "unprognostic (3.54e-2)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-4)" 42.7 36.8 25.0 17.4 26.3 9.0 40.3 24.0 25.7 53.3 17.3 44.5 17.3 57.8 22.4 30.9 46.7 20.4 50.5 24.7 27.5 42.6 25.6 38.2 16.3 27.0 29.0 69.0 58.1 34.3 38.9 24.9 25.2 37.5 18.7 20.3 36.1 24.9 53.8 35.2 36.4 29.9 25.0 35.1 36.3 40.6 29.5 20.0 43.1 16.4 18.9 42.3 40.8 30.0 38.4 52.2 44.7 43.3 113.7 113.2 42.8 45.0 64.2 48.6 68.3 34.4 116.0 22.8 59.8 102.9 35.8 71.1 30.1 62.1 80.1 10.3 26.1 17.9 37.8 54.3 70.5 29.3 12.6 68.0 32.8 63.6 66.3 91.3 100.8 54.8 19.0 24.9 44.2 70.0 14.1 26.0 34.7 81.2 20.6 33.9 32.6 59.5 31.6 17.1 15.8 23.3 87.3 24.9 25.0 47.7 28.2 36.5 79.1 46.1 40.9 48.2 30.3 47.4 51.2 41.1 86.3 22.5 46.6 3.2 16.7 13.3 19.1 15.7 19.2 11.6 23.8 20.9 18.5 10.1 28.2 22.6 7.3 15.4 19.9 18.4 21.0 19.0 25.0 26.3 24.0 25.7 24.7 27.5 27.0 29.0 25.2 25.0 29.5 30.0 52.8 64.1 50.7 114.3 46.4 27.1 27.2 33.0 55.8 68.5 35.6 35.6 79.5 77.2 39.7 51.5 146.0 78.0 75.6 33.5 7.9 39.9 39.7 49.2 79.3 62.0 38.6 25.0 133.4 42.5 43.6 101.4 38.7 58.0 3.8 91.0 75.3 40.7 50.1 70.7 155.3 31.9 24.4 68.8 42.1 28.1 96.9 44.4 42.7 62.8 64.8 59.6 111.2 97.5 137.3 40.8 28.8 114.3 100.2 33.6 47.8 44.2 44.3 57.9 92.1 84.6 59.9 89.2 87.9 30.5 21.6 75.2 72.4 72.4 32.9 26.4 GLMP "C1orf85, MGC31963, NCU-G1" ENSG00000198715 "Glycosylated lysosomal membrane protein" Q8WWB7 1 156290089-156295689 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029121 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA029121: AB_10600794" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (5.68e-2)" "unprognostic (4.22e-3)" "unprognostic (3.71e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.35e-5)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (9.21e-3)" "unprognostic (1.33e-1)" "unprognostic (7.66e-3)" "unprognostic (7.68e-3)" "unprognostic (3.90e-2)" "unprognostic (1.96e-1)" "unprognostic (1.13e-1)" "unprognostic (4.20e-3)" 33.9 68.3 11.8 17.1 12.8 19.4 25.6 12.9 15.4 38.1 21.1 24.6 30.3 24.4 23.2 29.8 21.1 44.7 18.1 11.7 13.9 52.2 59.8 28.9 22.6 13.6 13.6 22.0 27.0 29.4 19.7 48.0 15.0 57.3 21.1 2.7 35.2 20.4 7.4 29.2 26.9 24.5 12.4 32.3 28.8 6.4 16.0 12.2 23.6 9.6 15.4 36.0 26.8 14.4 22.7 40.8 3.9 27.0 224.8 121.7 27.5 40.8 172.0 58.1 79.0 50.9 68.7 0.0 83.2 59.0 1.9 14.6 0.6 30.0 18.4 4.6 41.8 7.0 22.9 60.6 101.4 19.7 58.1 119.9 36.0 55.9 17.9 85.1 89.0 17.6 32.8 3.1 34.6 28.5 10.1 0.1 46.5 56.9 20.9 17.4 0.0 74.3 53.7 24.5 12.9 42.2 27.1 76.4 120.6 45.6 38.3 54.2 45.7 25.7 5.0 46.2 26.9 24.9 45.9 11.3 44.0 15.7 36.3 35.0 71.3 12.2 23.4 74.5 21.7 13.1 23.0 20.5 31.8 7.7 22.7 21.7 19.4 18.0 55.6 21.3 43.4 36.9 11.8 12.8 12.9 15.4 11.7 13.9 13.6 13.6 15.0 12.4 16.0 14.4 11.7 3.2 19.1 3.3 7.3 0.0 16.4 0.0 10.8 2.0 12.3 11.6 5.8 31.5 5.0 31.3 0.0 70.3 7.6 13.8 27.4 51.3 0.6 8.5 19.1 17.5 10.9 18.5 1.6 38.3 68.5 33.4 18.8 14.2 8.8 14.9 42.8 69.8 197.7 1.7 1.9 19.4 0.0 66.8 0.0 1.4 16.4 41.1 0.0 1.0 29.8 21.0 13.4 2.0 3.9 29.8 22.2 13.9 23.0 28.9 44.9 67.3 5.8 1.5 13.1 11.9 17.1 0.9 1.9 17.8 0.0 69.6 9.3 17.6 11.8 18.7 GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 10.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 25.3;Early spermatids: 24.7;Excitatory neurons: 52.4;Inhibitory neurons: 11.2;Late spermatids: 22.8" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.75e-3)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (9.02e-2)" "unprognostic (3.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.64e-5)" "unprognostic (4.61e-4)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" 0.0 0.8 4.2 0.0 3.4 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 4.5 0.0 0.0 0.0 0.2 0.8 3.6 0.0 0.4 0.0 0.6 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.5 10.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.2 3.4 0.0 3.0 2.6 4.5 0.8 3.6 0.6 0.9 10.5 0.0 0.0 0.0 0.6 1.3 1.6 0.0 1.3 0.0 0.0 5.0 25.3 0.3 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 0.1 0.4 0.0 0.0 52.4 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.0 2.8 0.0 0.2 0.0 1.0 1.0 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.6 0.0 1.0 0.3 0.7 1.6 0.1 0.1 0.0 0.3 0.0 0.0 0.4 GLUD1 "GDH, GLUD" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 816.4" "Cell type enhanced" "Detected in all" "Astrocytes: 294.1;Hepatocytes: 402.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 555.0" "Low region specificity" "Detected in all" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" NA NA 23000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" 70.1 93.0 217.2 44.8 219.0 29.2 96.4 180.4 216.8 50.2 135.8 63.4 80.9 48.1 30.0 77.0 47.4 53.3 75.6 193.3 223.2 249.2 816.4 57.7 42.9 220.9 222.9 71.6 66.2 39.0 37.1 58.8 202.3 110.5 61.5 90.2 55.6 53.2 51.1 84.2 88.6 53.3 223.2 46.4 57.0 22.3 254.6 44.8 68.1 64.4 59.2 68.1 55.6 202.3 127.1 100.3 77.1 131.5 143.0 174.5 84.0 97.7 167.8 92.4 100.5 233.0 120.6 141.5 77.8 143.4 53.0 194.7 101.4 98.5 98.0 102.7 79.8 69.0 55.9 555.0 318.1 163.2 95.5 121.3 181.5 103.2 304.9 140.3 112.0 109.3 70.7 124.0 101.0 92.1 148.1 145.7 88.2 136.9 79.8 110.4 98.3 93.1 267.4 101.8 39.7 73.9 87.8 68.8 126.1 73.9 94.3 112.8 112.4 47.8 42.5 98.2 101.0 73.6 81.4 167.5 115.3 182.8 29.3 9.1 14.2 9.7 8.3 11.1 10.3 9.8 11.2 10.1 15.9 11.3 9.9 8.0 1.2 13.6 16.0 5.9 12.6 6.5 217.2 219.0 180.4 216.8 193.3 223.2 220.9 222.9 202.3 223.2 254.6 202.3 49.3 22.4 23.9 294.1 56.6 106.0 57.5 32.2 105.3 22.5 83.3 38.2 60.2 57.2 47.3 60.7 37.5 95.7 45.6 56.1 156.5 32.5 14.2 37.3 44.0 54.1 39.4 52.6 35.8 33.8 63.8 89.0 86.2 59.7 43.2 33.6 50.7 402.3 69.1 15.2 38.0 49.5 36.7 74.1 184.5 26.0 88.0 81.4 104.9 42.2 50.6 140.0 39.1 48.7 42.9 50.2 38.3 90.7 75.7 103.4 124.2 175.5 21.6 68.9 65.7 41.3 55.9 11.4 8.6 189.5 122.3 47.6 84.6 70.9 49.6 107.3 GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.9;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Cytotrophoblasts: 4.6;Early spermatids: 2.6;Hepatocytes: 4.6;Proximal tubular cells: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 3.7;K-562: 4.3;OE19: 2.1;SK-MEL-30: 5.5;THP-1: 2.7;WM-115: 6.0" "HPA042492, HPA044839, HPA061369" Uncertain Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.44e-1)" "unprognostic (5.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (2.42e-1)" "unprognostic (2.61e-1)" "unprognostic (2.35e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.04e-2)" "unprognostic (1.49e-2)" "unprognostic (4.77e-3)" "unprognostic (5.96e-2)" 1.7 1.7 0.0 0.1 0.3 0.0 1.2 0.0 0.8 0.4 0.5 0.5 0.0 0.4 1.7 0.5 0.4 0.4 0.9 0.4 0.0 1.6 3.9 0.5 0.1 0.0 0.0 0.4 1.0 0.5 0.4 0.8 0.0 0.4 0.0 0.1 0.6 0.2 0.5 0.6 0.4 0.1 0.0 0.1 0.6 15.4 0.1 0.0 0.4 0.1 0.1 0.4 0.4 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.8 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.1 1.2 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.8 0.0 0.0 2.3 0.1 0.0 0.5 0.0 0.6 0.0 0.4 0.1 2.6 0.0 0.0 0.0 2.1 4.6 0.1 0.1 1.9 0.2 2.6 0.6 0.8 0.9 0.0 0.0 1.2 0.4 0.5 0.8 0.0 0.5 0.0 0.1 0.0 4.6 0.5 0.0 0.4 0.1 0.0 1.2 0.3 2.2 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.2 3.3 0.0 0.1 0.0 0.9 0.4 1.2 1.0 0.1 0.1 2.5 0.3 0.7 0.2 0.3 GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 231.4" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 184.8;Paneth cells: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 25: Pancreas - Digestion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "CAB011458: AB_2110946, CAB047327: , CAB047328: , HPA049977: AB_2680978, HPA054597: AB_2682538" "unprognostic (1.37e-1)" "unprognostic (3.43e-3)" "unprognostic (3.91e-3)" "unprognostic (1.52e-2)" "unprognostic (1.28e-1)" "unprognostic (4.37e-2)" "unprognostic (2.90e-3)" "unprognostic (8.29e-2)" "unprognostic (1.23e-3)" "prognostic favorable (4.13e-4)" "prognostic unfavorable (9.77e-4)" "unprognostic (1.33e-2)" "prognostic unfavorable (7.82e-5)" "unprognostic (2.25e-1)" "unprognostic (7.92e-2)" "unprognostic (3.63e-2)" "unprognostic (5.90e-3)" 10.1 7.7 16.9 17.2 18.2 68.9 24.2 19.5 23.7 11.1 13.5 41.6 17.8 10.6 5.8 16.6 16.5 7.9 8.0 14.7 20.2 24.6 18.2 8.9 30.4 17.0 20.2 14.6 231.4 8.4 11.1 16.5 17.8 41.5 44.4 16.3 8.7 24.9 7.4 40.3 16.1 12.5 16.4 19.1 22.6 37.4 19.8 37.4 10.8 14.3 23.7 28.4 13.9 15.5 110.9 64.2 159.2 66.2 22.2 23.5 106.0 106.0 55.9 124.4 135.5 125.1 38.8 110.1 131.3 34.4 91.3 63.3 139.4 78.1 133.0 41.2 145.4 151.5 109.3 207.4 20.7 119.1 53.1 19.1 25.1 75.9 29.5 25.8 62.2 84.6 193.9 56.9 88.9 86.3 224.9 128.2 87.3 89.6 50.2 128.9 124.4 141.2 53.5 94.6 127.3 78.3 47.5 77.4 95.2 89.1 81.3 72.0 30.9 75.7 76.8 88.3 182.6 62.8 207.6 210.3 23.1 220.9 111.2 5.5 5.2 17.1 4.4 6.9 5.6 9.2 8.5 6.9 7.6 4.6 6.1 6.9 3.0 5.9 5.0 9.4 15.9 5.6 16.9 18.2 19.5 23.7 14.7 20.2 17.0 20.2 17.8 16.4 19.8 15.5 24.0 6.4 15.6 8.8 17.0 33.0 28.4 57.4 18.8 9.5 51.0 52.5 12.1 18.6 68.1 44.1 2.1 83.2 19.9 72.6 9.8 113.6 94.8 84.8 30.6 18.4 25.9 66.2 3.5 112.3 136.3 17.7 12.2 184.8 13.3 36.4 13.9 17.4 54.0 11.8 5.3 66.3 10.2 10.7 13.2 28.0 9.6 15.2 23.2 5.6 12.6 30.9 6.2 5.5 3.2 31.8 300.5 10.9 41.6 25.6 20.8 20.6 25.2 13.7 19.7 8.0 21.9 158.8 58.8 26.8 63.5 48.7 19.1 30.4 156.5 30.1 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1364113 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 135.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 560000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" 34.8 94.0 33.5 19.3 41.3 25.0 34.5 37.8 43.3 31.4 43.2 27.9 17.7 29.7 28.9 23.6 28.5 23.7 28.7 32.6 34.8 37.1 40.9 28.4 27.9 38.8 35.5 35.7 39.6 40.2 32.9 20.9 39.3 29.9 16.2 15.6 42.9 20.7 34.6 37.2 30.9 14.9 35.1 38.3 34.8 21.4 35.7 13.3 33.9 16.9 14.4 28.8 26.5 44.5 13.3 21.2 15.3 26.9 135.2 50.3 20.1 38.3 49.6 14.9 28.4 19.1 37.0 8.4 43.0 51.8 22.5 24.0 9.2 22.4 7.6 27.0 20.2 11.3 73.9 33.0 57.6 18.2 43.2 67.3 38.4 14.2 20.3 41.6 27.5 15.2 13.7 48.4 24.6 30.7 8.7 18.7 14.4 33.9 11.8 30.5 12.9 38.6 37.3 17.1 12.0 15.5 38.5 39.2 28.7 8.5 36.9 27.3 27.0 29.8 25.5 24.6 19.1 50.6 40.4 17.7 24.4 15.6 20.3 70.5 77.0 49.5 43.3 74.4 39.6 32.1 36.7 40.8 61.5 31.1 33.4 30.8 32.0 32.6 73.9 52.2 46.9 49.7 33.5 41.3 37.8 43.3 32.6 34.8 38.8 35.5 39.3 35.1 35.7 44.5 39.7 41.7 41.7 17.3 31.9 20.9 26.5 25.4 46.7 15.1 34.0 42.9 9.4 37.1 43.2 20.2 25.0 25.0 34.9 25.8 9.8 27.4 2.6 17.7 29.8 25.6 9.1 9.9 22.7 14.5 20.3 49.7 47.4 23.7 24.6 21.1 30.7 35.2 50.2 8.4 20.5 18.0 14.2 43.4 41.7 4.6 30.1 47.8 33.8 9.4 25.7 31.0 30.9 15.1 32.4 14.8 32.9 17.7 76.1 22.1 32.1 41.7 28.5 24.5 19.7 24.4 22.9 25.4 24.2 48.1 20.3 31.1 30.6 20.5 21.7 24.5 GOLT1A "CGI-141, FLJ42654, GOT1, MGC62027, YMR292W" ENSG00000174567 "Golgi transport 1A" Q6ZVE7 1 204198163-204213988 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 190.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 131.3;Proximal enterocytes: 206.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 80.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 18.0;CAPAN-2: 20.0;Hep G2: 25.9;MCF7: 43.5;OE19: 16.1;RT4: 27.7;SK-BR-3: 27.2" "Region enhanced" "Detected in many" "cerebral cortex: 9.0" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.43e-1)" "unprognostic (1.13e-1)" "unprognostic (2.22e-3)" "unprognostic (2.66e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (6.20e-3)" "unprognostic (2.14e-1)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.26e-2)" "unprognostic (7.33e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.35e-5)" "unprognostic (1.37e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-3)" "prognostic favorable (1.51e-4)" 0.3 0.1 6.1 0.4 9.2 0.0 5.3 7.0 5.3 10.9 3.9 5.6 47.4 0.3 10.7 0.5 3.3 1.6 0.1 4.3 11.2 16.2 190.7 8.3 0.1 4.7 5.3 0.1 22.3 18.3 30.4 3.5 4.7 5.3 5.0 1.5 3.4 2.1 0.3 0.5 45.5 0.3 4.5 0.1 8.2 2.6 11.6 0.8 0.7 0.0 0.2 13.1 0.4 2.8 0.5 8.2 0.0 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.0 18.0 20.0 0.0 0.7 0.2 0.0 0.6 0.0 0.1 0.1 0.0 0.3 0.1 0.0 25.9 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 43.5 0.0 0.1 4.0 16.1 0.2 0.0 0.1 0.4 8.5 27.7 1.3 1.8 0.8 27.2 0.1 0.7 8.9 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 6.1 9.2 7.0 5.3 4.3 11.2 4.7 5.3 4.7 4.5 11.6 2.8 0.1 0.0 19.5 0.3 0.1 0.0 12.7 2.6 2.8 1.7 7.2 4.7 0.2 40.0 5.1 16.5 0.0 13.3 0.1 7.0 13.7 29.2 0.9 0.5 0.1 0.3 10.3 0.0 2.2 19.1 0.5 1.1 8.2 2.0 1.3 1.4 1.8 131.3 1.3 1.7 0.7 7.8 2.0 1.6 0.0 0.4 0.0 0.2 1.8 0.0 0.0 0.0 0.0 4.5 0.1 18.7 5.6 0.0 0.0 15.0 206.8 14.7 0.3 0.2 0.0 0.3 0.3 2.9 0.9 1.4 0.1 26.4 0.5 0.2 12.5 20.5 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" 23.6 33.6 13.5 28.0 15.3 28.4 42.4 29.7 17.6 24.7 25.0 21.3 19.7 28.6 12.8 16.3 21.0 23.1 20.4 13.4 15.0 30.1 32.7 23.9 22.3 16.2 16.5 23.0 23.1 40.5 16.2 27.2 15.6 18.3 21.7 15.4 25.4 20.3 57.6 18.4 19.0 33.2 15.4 21.2 26.8 24.2 15.7 22.1 20.0 39.9 27.4 24.6 18.8 16.8 39.0 42.4 49.7 38.9 53.1 64.1 43.7 82.7 70.8 61.4 63.6 28.7 76.1 53.8 56.6 68.7 75.4 22.0 58.7 37.3 78.8 58.0 32.4 63.0 49.0 26.5 31.0 6.8 87.1 40.6 26.9 64.0 23.0 52.5 64.1 52.7 47.9 61.5 63.4 16.5 60.0 17.3 53.1 71.3 22.5 34.7 49.8 29.2 36.4 57.5 32.4 44.7 32.2 43.9 89.1 56.5 60.9 42.4 47.0 63.0 43.8 73.0 62.6 33.0 47.9 58.7 51.9 36.9 63.1 16.0 17.0 7.8 12.5 15.9 11.6 8.6 9.6 12.6 21.0 9.9 8.5 8.5 3.8 5.8 14.3 8.0 9.7 13.8 13.5 15.3 29.7 17.6 13.4 15.0 16.2 16.5 15.6 15.4 15.7 16.8 20.0 3.2 31.2 0.0 14.5 0.0 13.2 0.0 11.4 16.9 50.2 19.6 0.0 27.1 13.6 11.0 10.4 33.9 18.4 10.8 3.9 41.3 40.6 14.1 19.4 21.7 17.0 21.5 0.0 39.8 42.5 13.1 27.0 29.2 2.5 21.2 18.2 62.4 27.1 15.2 0.0 14.2 0.0 28.1 0.0 58.7 12.8 31.7 0.0 0.0 31.2 11.8 9.2 0.0 0.0 44.9 11.3 10.5 23.9 27.7 13.3 28.2 5.8 15.1 6.6 20.3 11.6 4.3 14.8 10.1 0.0 40.4 16.7 23.0 11.1 18.2 GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531978-98534681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 31.3" "Cell type enriched" "Detected in some" 8 "Plasma cells: 31.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory B-cell: 3.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 5.1;T-reg: 12.1" "Group enriched" "Detected in many" 26 "B-cells: 3.6;T-cells: 12.1" "Group enriched" "Detected in some" 5 "HDLM-2: 4.6;U-266/70: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA013775 Approved NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA013775: AB_1849264" "unprognostic (8.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.72e-3)" "unprognostic (5.66e-2)" "unprognostic (9.48e-3)" "unprognostic (5.60e-5)" "unprognostic (5.17e-1)" "unprognostic (6.77e-3)" "unprognostic (3.96e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.83e-1)" "unprognostic (4.04e-3)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" 0.6 0.0 0.0 4.5 0.2 0.2 3.8 0.1 0.2 0.5 0.0 20.0 2.7 0.2 0.0 2.5 0.1 2.3 0.1 0.0 0.1 0.2 0.3 1.9 2.4 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.4 31.3 0.0 4.9 0.2 0.0 0.3 10.2 0.8 0.1 5.3 1.6 0.0 0.1 1.9 0.4 0.0 5.3 7.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.3 3.6 10.8 5.1 0.0 0.6 0.5 0.8 0.3 0.0 0.0 0.2 12.1 2.1 0.0 0.2 0.1 0.2 0.0 0.1 0.5 0.3 0.4 0.1 0.1 0.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;lymphoid tissue: 38.9;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 172.6;Late spermatids: 190.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.3;NK-cells: 52.9;T-cells: 41.9" "Group enriched" "Detected in some" 4 "Daudi: 8.1;THP-1: 20.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013873 Enhanced NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" 0.4 0.1 0.2 12.2 0.3 9.7 0.2 0.7 0.4 0.3 0.9 0.9 1.0 0.4 0.2 0.5 0.2 1.2 0.3 0.2 0.1 0.3 0.9 0.7 38.9 0.7 0.2 0.1 0.1 0.0 0.1 0.1 0.4 0.4 1.0 0.0 0.9 0.1 0.1 0.3 4.1 0.2 0.1 10.5 1.5 13.0 0.3 7.9 0.4 0.1 32.5 2.1 0.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 2.9 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 3.5 0.0 0.2 1.9 0.5 24.4 5.5 41.3 65.3 22.1 34.0 12.6 53.3 41.9 38.9 2.2 52.9 5.3 12.5 6.4 13.1 0.2 0.3 0.7 0.4 0.2 0.1 0.7 0.2 0.4 0.1 0.3 0.4 0.2 0.0 1.3 0.3 44.7 0.3 0.0 0.0 0.0 1.0 0.1 0.3 1.0 0.0 0.6 0.0 0.0 0.0 14.4 0.1 0.0 0.0 172.6 1.3 0.2 0.2 1.2 6.1 0.4 0.0 0.0 0.2 1.1 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.3 1.2 190.5 0.9 3.9 0.0 0.0 0.6 0.0 18.6 0.5 0.1 0.0 0.1 1.2 1.4 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.2 1.8 0.4 0.0 0.3 0.0 20.5 0.1 0.1 0.1 GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 12.1;Early spermatids: 20.6;Late spermatids: 19.4;Oligodendrocyte precursor cells: 18.6;Spermatocytes: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "A-431: 32.0;CAPAN-2: 26.9;hTEC/SVTERT24-B: 30.8;RT4: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" 0.2 0.0 0.7 0.9 0.7 0.0 2.1 0.5 0.7 4.4 1.3 6.8 4.6 0.4 0.8 0.8 3.6 2.2 0.0 0.4 0.7 2.6 3.3 3.9 0.0 1.6 2.2 0.0 3.9 5.1 0.1 0.1 2.0 0.5 5.7 0.0 0.5 1.0 0.0 1.0 3.7 0.3 1.2 0.0 6.1 0.2 0.7 0.0 1.3 0.0 0.2 2.6 0.6 0.2 32.0 18.1 0.3 0.0 0.5 3.6 0.0 2.8 11.1 5.8 3.3 17.7 26.9 0.0 9.7 1.9 13.1 18.6 0.0 12.9 5.7 0.1 0.0 0.0 1.9 0.7 0.6 0.0 0.0 1.1 9.7 30.8 3.1 7.0 0.1 0.0 0.0 0.0 4.2 3.0 0.0 0.0 0.3 7.3 10.5 0.0 0.5 0.0 21.2 27.9 0.0 0.1 2.0 10.3 0.1 1.1 5.8 0.0 5.6 12.4 12.2 4.2 16.8 0.0 0.0 0.1 18.9 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.7 0.5 0.7 0.4 0.7 1.6 2.2 2.0 1.2 0.7 0.2 0.0 16.0 8.7 12.1 0.0 0.1 0.7 2.4 0.0 0.2 1.5 0.9 0.2 2.8 6.7 0.0 0.0 0.0 2.7 10.3 0.0 5.6 20.6 2.6 0.2 0.1 2.4 0.0 3.9 3.1 0.0 0.2 4.1 1.8 0.0 0.0 0.0 3.6 0.0 0.0 4.9 1.6 0.0 0.6 0.3 19.4 0.3 0.3 0.0 1.0 0.6 1.4 0.0 18.6 1.8 5.9 3.0 0.4 0.1 0.3 1.9 0.7 6.1 0.0 0.0 0.1 0.3 32.4 1.2 0.5 0.0 0.0 0.0 0.0 4.9 1.2 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940775-12952147 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skin 1: 47.8" "Cell type enhanced" "Detected in some" "Early spermatids: 6.8;Gastric mucus-secreting cells: 5.6;Late spermatids: 6.2;Melanocytes: 5.4;Plasma cells: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "memory B-cell: 21.9;naive B-cell: 7.5" "Lineage enriched" "Detected in many" 14 "B-cells: 21.9" "Group enriched" "Detected in many" 9 "Karpas-707: 84.5;RPMI-8226: 85.9;U-266/84: 25.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA071909: AB_2686470" "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" 0.9 0.6 0.2 0.4 0.4 0.6 3.0 0.1 0.2 1.2 2.0 2.7 1.8 0.2 0.0 2.5 0.3 0.8 0.8 0.2 0.4 0.6 1.0 7.2 0.7 1.1 1.2 0.5 2.1 0.0 1.5 0.3 0.5 1.2 2.3 0.3 4.5 0.0 0.2 47.8 2.7 0.0 0.3 1.6 2.3 2.7 0.6 0.1 1.2 0.0 1.1 0.7 1.0 0.3 1.3 1.4 0.0 1.5 0.0 0.0 3.3 0.4 0.0 0.0 0.3 1.3 3.2 0.1 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 7.6 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 84.5 0.2 3.1 0.0 0.0 0.8 3.9 0.1 0.1 0.0 85.9 0.0 3.4 2.6 0.5 1.9 1.4 0.0 3.5 0.0 0.0 2.3 0.0 3.9 0.1 0.0 4.4 25.2 1.1 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 21.9 0.2 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.4 0.1 0.2 0.2 0.4 1.1 1.2 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.1 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 5.6 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.3 0.0 6.2 0.0 0.1 5.4 1.9 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 GPSM2 "DFNB82, LGN, Pins" ENSG00000121957 "G protein signaling modulator 2" P81274 1 108875350-108934545 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 46.9;tongue: 54.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 133.5;Oligodendrocyte precursor cells: 134.7;Oligodendrocytes: 127.4;Syncytiotrophoblasts: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.2;T-reg: 1.8" "Group enriched" "Detected in many" 5 "granulocytes: 3.2;T-cells: 1.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007327, HPA008408, CAB018962" Uncertain Supported Cytosol NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "CAB018962: , HPA007327: AB_1849941, HPA008408: AB_1849939" "unprognostic (1.97e-1)" "unprognostic (6.80e-2)" "prognostic favorable (7.86e-5)" "unprognostic (1.37e-3)" "unprognostic (3.18e-2)" "unprognostic (1.97e-2)" "unprognostic (8.57e-6)" "unprognostic (7.12e-2)" "unprognostic (2.76e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (7.55e-3)" "prognostic unfavorable (3.02e-4)" "unprognostic (6.27e-3)" "unprognostic (1.00e-1)" "unprognostic (5.14e-3)" "unprognostic (6.00e-2)" 5.3 3.5 27.3 4.4 39.5 14.4 7.5 33.8 25.2 12.6 10.8 15.3 9.1 6.8 2.6 34.1 4.2 2.6 4.3 23.3 29.5 2.3 2.9 9.0 6.4 33.9 36.3 3.3 3.6 9.7 3.1 7.7 33.9 5.9 15.2 8.6 10.1 4.7 10.7 37.7 11.5 10.5 32.1 2.7 5.1 11.5 34.1 18.4 3.2 54.4 13.2 6.0 17.7 46.9 135.6 16.2 36.8 27.7 36.4 20.2 30.0 24.2 61.4 29.9 45.4 16.0 31.7 30.5 6.7 33.4 21.0 28.3 25.3 59.1 39.6 30.7 15.8 19.8 34.7 16.5 4.8 28.6 18.5 4.1 113.9 29.4 129.8 9.4 26.9 19.5 14.9 42.3 58.4 37.8 26.1 12.2 8.7 52.1 29.4 20.1 66.7 6.6 24.3 18.6 30.4 26.9 37.0 69.2 26.9 10.3 27.6 24.3 18.0 21.7 36.7 64.8 48.5 18.4 20.9 28.6 34.3 47.4 108.9 0.1 0.3 3.2 0.2 0.3 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.3 0.3 0.1 0.1 0.1 1.8 0.1 27.3 39.5 33.8 25.2 23.3 29.5 33.9 36.3 33.9 32.1 34.1 46.9 4.6 16.0 3.3 63.0 5.7 62.7 18.8 12.9 47.3 47.7 3.0 3.7 2.5 2.8 12.5 7.3 133.5 46.3 6.7 10.8 11.7 2.5 54.0 5.2 20.6 5.1 9.1 33.9 11.7 1.9 47.7 19.5 8.6 9.2 2.5 14.4 2.9 1.6 9.0 43.7 24.0 14.1 10.2 5.3 11.3 21.3 18.6 4.9 26.6 3.7 5.3 8.0 2.1 134.7 127.4 4.8 7.8 5.3 5.3 5.6 8.4 0.9 9.0 48.1 0.0 43.6 6.9 20.6 28.9 24.0 40.6 89.2 7.1 10.0 18.7 15.5 GPX1 ENSG00000233276 "Glutathione peroxidase 1" P07203 3 49357176-49358353 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3273.8;Kupffer cells: 3971.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1534.3;granulocytes: 1010.7;monocytes: 1337.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011582, HPA044758" Approved Supported Cytosol NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "CAB011582: AB_2112120, HPA044758: AB_2679076" "unprognostic (1.50e-2)" "unprognostic (4.34e-3)" "unprognostic (1.25e-1)" "prognostic favorable (7.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (6.73e-3)" "unprognostic (5.03e-2)" "unprognostic (3.40e-2)" "unprognostic (2.48e-1)" "unprognostic (5.46e-2)" "unprognostic (1.53e-1)" "unprognostic (7.64e-3)" "unprognostic (9.14e-3)" "unprognostic (3.16e-2)" "unprognostic (5.72e-3)" "unprognostic (7.64e-3)" 321.4 200.0 178.3 151.9 186.6 246.7 151.5 190.2 298.9 90.9 247.3 86.9 122.2 82.2 17.8 134.3 86.5 91.1 95.5 173.1 198.9 152.9 281.6 168.3 174.3 234.0 213.0 61.9 74.4 35.2 85.7 121.2 208.3 107.0 42.7 8.3 113.1 53.9 157.1 70.4 113.6 70.4 218.0 195.9 92.9 31.5 217.6 75.3 82.1 61.7 86.6 116.8 94.9 256.3 322.8 189.2 72.6 95.4 113.5 205.9 225.9 217.7 114.7 151.5 80.1 157.8 229.7 0.6 301.6 139.8 181.7 93.2 98.8 660.3 31.6 200.2 271.6 224.8 190.2 397.4 575.6 161.0 594.4 455.9 267.6 292.4 221.5 190.0 341.5 78.6 0.5 179.3 125.9 0.8 51.2 407.0 441.3 147.4 510.5 190.8 93.8 120.3 258.2 385.6 87.7 178.5 249.5 1.5 287.3 75.7 1.5 559.5 546.5 209.7 236.0 385.8 453.6 1.1 127.9 116.3 390.5 436.3 507.8 1010.7 1337.0 707.6 69.8 483.7 100.9 314.2 127.7 83.7 1093.1 276.8 118.4 116.2 136.4 107.4 275.8 1534.3 233.3 1401.2 178.3 186.6 190.2 298.9 173.1 198.9 234.0 213.0 208.3 218.0 217.6 256.3 0.0 109.0 323.5 6.2 148.1 249.7 432.8 985.0 92.2 32.1 0.0 0.0 0.0 220.2 616.7 0.0 10.4 499.9 491.5 229.5 0.0 0.0 300.7 0.0 0.0 227.8 251.3 364.1 12.8 0.0 830.3 131.0 73.4 0.0 480.6 0.0 585.7 888.1 3273.8 1.7 17.9 285.0 386.6 3971.6 965.7 1102.9 134.5 1305.5 273.9 41.2 828.6 63.4 138.0 8.0 7.6 0.0 179.0 67.0 82.4 481.0 349.9 0.0 490.0 14.6 210.4 150.6 151.8 12.7 169.4 112.1 154.1 278.8 112.2 0.0 367.3 517.0 GRAMD2A GRAMD2 ENSG00000175318 "GRAM domain containing 2A" Q8IUY3 15 72159806-72197787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.9;placenta: 48.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 70.5;Cytotrophoblasts: 106.2;Extravillous trophoblasts: 29.5;Syncytiotrophoblasts: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 165.5;SK-BR-3: 75.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029435 Uncertain Approved "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoli, Nuclear speckles" Cytosol "HPA029435: AB_10601811" "unprognostic (5.70e-2)" "unprognostic (7.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.24e-1)" "unprognostic (9.51e-3)" "unprognostic (2.95e-1)" "unprognostic (9.96e-2)" "unprognostic (3.90e-3)" "unprognostic (2.80e-1)" "unprognostic (1.96e-1)" "unprognostic (2.62e-1)" "unprognostic (5.77e-2)" "unprognostic (4.45e-1)" "unprognostic (2.35e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (7.29e-2)" 0.0 0.0 2.1 0.5 1.7 0.0 10.2 2.0 1.3 1.9 2.1 1.2 1.0 0.4 35.9 1.1 5.8 0.3 0.1 2.2 3.9 3.2 0.0 15.0 0.4 6.5 13.1 0.1 0.5 0.1 0.7 48.7 10.1 1.3 0.8 0.9 2.1 5.2 0.0 2.5 3.3 0.2 2.6 0.2 0.8 0.4 3.0 0.2 8.9 0.0 0.4 0.3 0.7 2.0 2.1 0.0 0.1 0.0 0.0 0.0 165.5 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.6 0.0 0.0 1.2 0.0 10.0 0.2 0.0 0.2 0.3 0.1 0.0 1.2 0.0 0.0 0.1 2.1 0.0 7.5 0.0 0.2 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.2 0.1 1.7 0.1 0.3 75.8 0.1 5.5 3.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 2.0 1.3 2.2 3.9 6.5 13.1 10.1 2.6 3.0 2.0 0.1 70.5 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.3 0.0 0.0 7.4 3.7 0.0 106.2 0.1 0.0 0.0 0.1 0.0 14.0 0.2 0.2 0.0 0.0 0.0 0.0 29.5 0.8 0.0 0.7 1.3 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 10.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 147.1 0.3 0.1 0.0 0.0 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;retina: 17.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 468.4;Horizontal cells: 198.5;Inhibitory neurons: 396.3;Oligodendrocyte precursor cells: 385.0" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 23.8;BJ hTERT+: 34.5;fHDF/TERT166: 45.9;U-2197: 15.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" 0.8 10.3 20.0 0.3 25.3 0.1 1.4 1.3 31.6 6.7 0.0 0.7 0.3 2.1 3.6 0.4 1.5 1.2 2.0 29.0 4.0 2.5 7.7 0.3 0.5 1.9 3.4 4.1 1.7 0.0 1.0 0.4 1.4 1.7 0.8 17.8 0.2 1.9 0.2 0.5 0.5 1.9 4.5 0.1 2.0 0.7 6.4 0.2 0.2 0.1 0.8 0.6 2.8 20.9 0.0 0.0 0.0 0.0 2.2 0.4 0.0 23.8 34.5 0.4 0.9 0.0 0.0 0.0 0.0 45.9 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 6.6 0.0 15.1 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 25.3 1.3 31.6 29.0 4.0 1.9 3.4 1.4 4.5 6.4 20.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.8 0.6 13.6 0.2 0.0 1.6 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.1 0.3 8.7 0.3 0.0 0.0 468.4 0.2 0.1 6.4 1.1 0.2 0.0 0.1 0.4 6.1 0.1 198.5 396.3 0.0 0.0 0.0 1.5 0.3 9.3 0.2 1.8 14.0 0.0 1.9 0.0 385.0 67.6 0.3 0.0 4.1 0.0 0.4 0.0 6.2 0.1 3.8 0.0 0.2 4.5 0.0 0.1 0.0 1.0 0.1 0.1 0.7 0.0 0.0 GRID1 "GluD1, KIAA1220" ENSG00000182771 "Glutamate ionotropic receptor delta type subunit 1" Q9ULK0 10 85599552-86366795 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.4" "Group enriched" "Detected in some" 19 "Astrocytes: 149.8;Excitatory neurons: 284.5;Inhibitory neurons: 301.2;Oligodendrocyte precursor cells: 316.2;Oligodendrocytes: 534.1" "Group enriched" "Detected in many" 5 "glioma: 3.6;thyroid cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.4;HEL: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (7.60e-2)" "unprognostic (2.75e-2)" "unprognostic (5.92e-2)" "unprognostic (4.31e-2)" "unprognostic (4.24e-1)" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.21e-2)" "unprognostic (5.09e-2)" "unprognostic (1.49e-3)" "unprognostic (8.30e-2)" "unprognostic (8.26e-2)" "unprognostic (4.58e-9)" "unprognostic (3.15e-3)" "unprognostic (5.91e-2)" "unprognostic (2.21e-1)" "unprognostic (8.65e-3)" 0.6 0.9 5.3 0.1 5.7 0.0 0.8 3.9 6.9 1.5 0.1 0.3 0.3 1.0 0.7 0.2 1.2 0.2 0.2 5.5 5.4 0.1 0.1 0.4 0.3 5.4 5.4 0.3 0.2 0.2 0.2 0.7 4.8 0.4 0.1 0.7 0.1 0.9 0.2 0.4 0.3 0.4 5.6 0.0 0.4 0.9 5.7 0.1 2.0 0.0 0.2 0.1 0.6 7.4 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.6 2.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.7 3.9 6.9 5.5 5.4 5.4 5.4 4.8 5.6 5.7 7.4 1.1 3.2 0.5 149.8 0.0 0.5 0.1 0.1 2.2 10.5 0.0 0.1 1.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.3 1.0 0.0 0.3 0.3 0.0 0.0 284.5 0.2 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 301.2 0.0 0.0 0.0 0.4 3.0 2.1 0.2 5.4 15.9 0.0 0.8 0.0 316.2 534.1 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.0 0.5 13.1 0.2 5.7 0.1 0.9 0.2 0.0 0.1 0.1 0.0 0.0 0.0 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2486.9" "Cell type enhanced" "Detected in all" "Adipocytes: 1649.5;Fibroblasts: 4145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1135.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1313.9;HaCaT: 533.6" "Region enriched" "Detected in all" 4 "white matter: 869.2" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" NA NA 112000000000 240000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" 1892.9 162.5 169.7 109.7 317.4 175.0 1244.6 291.2 213.0 577.4 155.6 867.4 152.0 767.7 108.2 435.1 663.2 226.1 2486.9 163.4 219.8 153.1 40.6 308.7 93.2 380.9 284.6 303.8 140.7 70.9 260.6 79.0 354.7 344.0 204.6 57.8 508.7 400.9 420.4 612.9 384.1 350.0 270.6 136.5 469.7 78.1 279.0 99.7 702.6 687.8 87.3 897.2 655.5 376.1 38.4 60.9 39.0 129.8 1313.9 351.8 26.4 130.9 264.7 30.1 56.5 64.2 130.1 3.0 36.6 182.8 48.5 533.6 3.2 84.3 16.9 6.5 7.6 31.2 57.1 167.5 32.0 7.0 146.0 140.0 84.9 51.7 34.4 83.1 120.4 6.1 10.4 5.3 137.0 81.1 0.4 304.4 12.7 76.2 45.1 8.4 13.1 4.3 156.4 63.4 7.7 10.4 60.9 62.5 197.2 84.6 245.3 158.8 217.4 100.0 33.2 10.4 12.8 1.8 2.0 3.2 105.3 18.2 278.1 302.9 122.0 1135.9 1.9 84.9 0.8 17.6 0.8 1.4 345.3 6.7 0.8 0.7 307.1 217.8 23.7 243.2 4.2 105.4 169.7 317.4 291.2 213.0 163.4 219.8 380.9 284.6 354.7 270.6 279.0 376.1 1649.5 147.4 55.7 82.3 22.7 341.2 278.1 252.7 103.0 7.5 120.8 212.0 272.0 85.8 354.3 121.4 77.2 55.8 74.9 557.7 105.7 258.5 9.9 141.9 163.1 724.8 63.1 17.2 17.1 202.3 94.3 4145.2 322.7 220.6 104.0 31.8 273.5 16.5 492.6 1.7 9.0 762.9 512.7 139.0 798.7 20.2 588.7 273.7 537.2 155.5 487.5 220.6 55.6 33.2 443.1 315.8 590.5 671.8 24.1 91.4 77.4 39.8 583.7 86.5 611.4 362.4 740.4 8.7 13.7 175.9 299.1 84.0 58.7 34.3 52.2 144.7 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 GTF3A "AP2, TFIIIA" ENSG00000122034 "General transcription factor IIIA" Q92664 13 27424619-27435823 "Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007990 Supported Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 52: Non-specific - Ribosome" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA007990: AB_1857960" "unprognostic (9.88e-3)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (8.64e-2)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-1)" "unprognostic (3.41e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (1.98e-1)" "unprognostic (1.33e-1)" "unprognostic (3.26e-1)" "unprognostic (1.41e-1)" 63.5 40.3 51.0 50.3 53.0 85.3 59.3 53.1 63.0 31.9 50.4 41.8 30.3 26.6 57.4 38.3 32.8 33.4 126.7 52.8 51.9 52.5 129.8 33.2 81.2 53.2 53.3 16.0 116.4 34.5 26.9 28.4 52.7 30.7 40.4 10.4 70.4 34.8 89.3 25.0 32.3 38.0 53.0 54.6 46.9 17.4 52.9 111.6 31.2 132.6 89.8 46.0 23.7 56.2 91.2 78.8 65.4 136.8 90.4 98.8 93.3 95.1 86.0 118.3 75.4 118.5 139.4 275.3 65.9 112.6 73.9 64.9 136.6 131.0 165.8 289.2 93.1 229.9 71.6 135.4 102.5 432.3 150.9 81.5 137.9 109.2 142.4 81.8 107.2 246.9 184.2 88.6 140.5 178.3 311.3 467.9 115.8 299.6 210.7 154.8 169.3 254.0 142.5 39.2 158.9 81.5 67.6 101.6 141.7 83.7 73.7 223.6 66.0 62.5 67.1 49.3 99.1 57.0 104.9 275.1 67.1 264.9 117.4 116.8 173.8 162.5 250.2 180.1 335.2 290.5 251.6 271.7 218.4 250.3 192.5 219.6 38.3 243.7 169.5 298.3 345.1 484.4 51.0 53.0 53.1 63.0 52.8 51.9 53.2 53.3 52.7 53.0 52.9 56.2 96.9 44.8 33.0 15.0 183.3 63.2 62.4 109.1 56.3 41.7 107.2 117.6 207.8 91.5 58.3 27.6 29.2 76.3 207.1 20.0 150.6 195.7 33.9 60.1 68.1 76.3 34.8 126.4 28.7 190.6 187.4 75.0 63.2 49.1 75.5 93.0 40.0 146.7 215.5 35.3 25.8 60.6 77.3 156.1 119.3 85.6 63.6 133.9 97.8 15.9 185.3 73.1 236.9 7.1 24.3 153.3 28.9 58.3 248.4 122.7 35.6 207.7 37.9 35.7 85.5 58.3 76.1 34.8 145.1 83.4 64.4 42.1 187.1 89.0 69.8 70.3 GUCY1A2 "GC-SA2, GUC1A2" ENSG00000152402 "Guanylate cyclase 1 soluble subunit alpha 2" P33402 11 106674019-107018476 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;placenta: 17.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 353.8;Inhibitory neurons: 141.8;Oligodendrocyte precursor cells: 208.6;Sertoli cells: 105.2;Smooth muscle cells: 107.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.8;BJ hTERT+ SV40 Large T+ RasG12V: 13.4;HBF TERT88: 7.1;TIME: 4.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009534 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009534: AB_2279509" "unprognostic (7.53e-2)" "unprognostic (6.67e-2)" "unprognostic (7.99e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (6.53e-3)" "unprognostic (9.70e-3)" "unprognostic (8.00e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.02e-5)" "unprognostic (2.48e-4)" "unprognostic (1.62e-1)" "unprognostic (3.50e-2)" "unprognostic (1.09e-2)" 3.4 2.0 5.3 0.6 18.4 0.0 1.9 1.6 13.8 12.7 0.0 0.7 0.2 12.3 3.1 0.4 5.9 1.5 2.7 7.1 3.9 1.8 1.7 4.6 0.7 4.7 2.6 1.2 4.3 0.6 0.5 17.9 4.9 1.8 0.5 3.5 0.6 6.8 1.8 0.6 0.4 13.1 0.4 6.0 0.3 1.7 8.6 0.2 1.4 3.6 0.3 0.9 2.8 7.4 0.0 0.2 4.0 0.0 0.2 2.4 2.2 0.3 11.8 1.5 13.4 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.1 0.0 7.1 0.0 1.1 0.0 0.1 0.0 0.2 0.0 1.6 0.6 0.0 1.8 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 3.6 0.0 0.7 0.5 0.8 0.2 4.6 3.7 3.0 0.8 1.2 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 18.4 1.6 13.8 7.1 3.9 4.7 2.6 4.9 0.4 8.6 7.4 29.5 0.0 0.5 20.2 0.5 1.7 2.2 0.0 1.2 24.0 0.4 0.9 5.1 0.0 0.0 3.7 12.5 0.1 0.0 0.1 0.0 5.8 2.5 0.9 24.2 12.5 0.0 2.7 353.8 0.2 0.0 8.2 0.0 1.1 0.0 42.7 2.2 0.2 0.4 18.5 141.8 0.0 0.0 0.8 1.5 6.5 24.5 1.1 3.6 18.7 0.0 29.3 0.0 208.6 10.7 0.3 0.0 25.2 1.2 2.4 0.0 0.1 0.0 4.8 105.2 20.7 107.0 1.6 1.5 0.7 1.1 0.3 0.5 19.6 0.0 1.5 GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 99.6" "Group enriched" "Detected in many" 4 "dendritic cells: 136.3;T-cells: 301.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 741.6;NK-cell: 505.5" "Group enriched" "Detected in many" 199 "NK-cells: 505.5;T-cells: 741.6" "Cell line enriched" "Detected in single" 10 "JURKAT: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA063181, HPA065895" Enhanced "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" 3.0 3.9 0.1 19.4 0.1 10.5 4.9 0.1 0.4 4.3 0.3 3.4 1.6 4.0 4.5 3.0 2.0 11.6 2.0 0.1 0.2 1.7 10.7 5.9 99.6 0.5 0.2 2.7 1.0 0.8 0.5 0.5 0.3 3.2 4.6 0.0 4.6 1.0 0.2 0.6 7.3 2.2 0.2 30.4 6.5 1.2 0.3 11.9 2.3 0.3 27.8 8.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 1.1 164.3 1.0 741.6 0.5 100.2 457.3 0.5 0.5 4.9 77.4 3.1 505.5 0.9 0.9 7.0 95.5 0.1 0.1 0.1 0.4 0.1 0.2 0.5 0.2 0.3 0.2 0.3 0.3 3.8 3.2 7.0 0.0 10.7 1.5 0.1 0.0 1.8 0.0 1.5 1.7 0.1 2.8 0.6 0.0 0.0 0.0 136.3 0.1 0.0 0.0 1.3 0.8 0.4 0.8 0.0 4.4 0.0 0.0 0.0 1.2 4.1 0.8 2.5 0.0 8.6 1.5 0.2 0.0 0.0 0.0 0.0 10.3 2.5 1.2 0.0 6.4 1.8 0.0 5.1 0.0 29.9 0.0 0.1 0.0 0.0 0.0 45.1 0.1 0.2 0.8 0.0 0.0 0.0 1.8 1.7 0.0 0.3 0.2 0.6 0.3 301.9 0.0 0.0 0.1 H1-3 "H1.3, H1d, H1F3, H1s-2, HIST1H1D" ENSG00000124575 "H1.3 linker histone, cluster member" P16402 6 26234212-26234987 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 21.1;brain: 24.1" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 4.4;dendritic cells: 23.3;Extravillous trophoblasts: 18.3;Hofbauer cells: 7.5;Plasma cells: 7.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 24.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "BEWO: 5.8;MOLT-4: 9.9;NB-4: 4.3;REH: 4.0;SiHa: 3.8;U-266/70: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055907 Supported NA NA 4000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA055907: AB_2682966" "unprognostic (8.78e-2)" "unprognostic (1.01e-4)" "unprognostic (8.69e-2)" "unprognostic (5.67e-2)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (2.13e-1)" "unprognostic (3.06e-2)" "unprognostic (1.99e-1)" "unprognostic (1.14e-2)" "unprognostic (8.96e-2)" "unprognostic (3.61e-8)" "unprognostic (8.78e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-2)" 1.2 0.1 1.3 0.2 0.5 21.1 1.1 24.1 4.6 1.7 3.4 1.5 0.0 0.1 0.1 0.7 0.4 0.0 0.4 0.5 1.4 0.6 0.3 1.3 1.9 2.5 1.8 0.3 0.0 0.0 0.1 0.5 4.5 1.4 0.7 0.0 0.5 0.0 0.0 2.4 2.5 0.1 3.8 1.3 0.6 0.3 2.6 5.5 0.5 0.0 0.4 0.2 3.8 7.0 0.7 0.5 0.1 0.0 0.2 0.0 5.8 0.3 0.2 0.7 0.5 0.1 0.6 0.0 0.1 0.1 0.3 0.7 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.8 1.7 1.7 0.1 0.0 9.9 4.3 0.5 0.0 1.7 4.0 0.1 2.2 0.0 0.0 1.9 0.3 3.8 1.6 0.0 0.5 0.7 0.9 0.0 0.2 0.0 0.1 0.6 4.8 2.5 0.3 0.6 1.2 0.5 22.3 7.5 6.5 31.4 4.4 21.9 32.1 28.7 21.7 18.2 46.7 37.1 30.6 2.6 25.8 6.9 32.8 23.4 14.1 1.3 0.5 24.1 4.6 0.5 1.4 2.5 1.8 4.5 3.8 2.6 7.0 3.5 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.4 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 18.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 3.6 3.6 0.0 0.0 0.0 H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 17.5;U-266/84: 6.3" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (5.03e-2)" "unprognostic (1.11e-2)" "unprognostic (7.27e-2)" "unprognostic (3.56e-1)" "unprognostic (9.17e-2)" "unprognostic (1.45e-1)" "unprognostic (9.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.92e-1)" "unprognostic (4.34e-1)" "unprognostic (1.81e-1)" "unprognostic (2.88e-2)" "unprognostic (1.10e-9)" "unprognostic (2.00e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (2.14e-2)" 0.7 0.2 0.4 0.3 1.7 2.9 0.6 4.1 2.1 3.3 3.6 0.5 0.0 0.1 0.0 2.5 0.6 0.3 0.4 1.0 1.9 0.6 1.2 2.1 0.5 3.1 1.7 0.7 0.1 0.0 0.3 0.2 2.1 2.1 0.1 0.0 0.5 0.0 0.0 1.1 0.5 0.0 3.9 1.2 0.6 0.3 3.0 1.8 0.3 0.0 0.3 0.3 2.8 6.8 1.1 0.0 0.2 0.2 0.0 0.0 0.2 0.7 0.1 1.1 0.0 1.3 0.4 0.7 1.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 1.0 0.3 1.4 1.3 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.7 2.5 1.3 0.0 0.0 3.7 1.5 1.1 0.0 1.1 1.0 0.4 0.9 0.4 0.1 1.4 0.2 0.6 0.8 0.1 0.0 1.4 0.3 0.0 1.1 3.1 0.0 1.0 17.5 6.3 2.2 1.0 1.3 0.4 2.3 0.3 3.8 1.3 1.9 1.3 2.7 2.0 4.0 1.1 7.6 1.9 1.9 17.9 1.8 2.2 6.2 2.7 0.8 0.4 1.7 4.1 2.1 1.0 1.9 3.1 1.7 2.1 3.9 3.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774383-14778002 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 565.0" "Cell type enhanced" "Detected in some" "Adipocytes: 58.1;Cytotrophoblasts: 130.2;dendritic cells: 56.4;Extravillous trophoblasts: 124.3;Fibroblasts: 59.5;Hofbauer cells: 241.2;Syncytiotrophoblasts: 160.3" "Cancer enhanced" "Detected in all" "prostate cancer: 151.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 256.2;MCF7: 338.4;RT4: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041189: AB_2677357" "unprognostic (9.38e-2)" "unprognostic (8.49e-2)" "unprognostic (9.15e-2)" "unprognostic (7.06e-2)" "unprognostic (2.43e-3)" "unprognostic (4.70e-2)" "unprognostic (3.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.37e-2)" "unprognostic (4.05e-2)" "unprognostic (3.32e-3)" "unprognostic (3.43e-2)" "unprognostic (8.66e-3)" "unprognostic (5.22e-3)" "unprognostic (3.87e-3)" 236.7 186.0 29.1 33.8 34.1 60.4 223.6 33.7 40.9 123.7 37.9 126.6 55.4 105.6 20.9 155.7 106.6 36.0 125.5 27.7 31.3 115.7 82.7 129.6 29.6 37.1 32.5 63.6 182.3 21.1 34.2 57.7 35.7 275.8 29.3 5.3 166.8 35.0 91.4 198.4 85.2 25.1 33.4 94.8 111.1 565.0 33.1 34.2 85.0 24.8 18.2 122.8 124.9 38.7 107.9 256.2 10.0 0.0 112.2 73.8 163.2 78.9 43.4 31.3 30.4 50.9 172.4 0.1 48.7 38.6 0.2 100.7 6.2 60.1 8.5 5.7 4.6 4.3 92.6 43.8 160.5 0.1 39.0 97.0 64.5 43.3 40.0 12.7 63.0 0.0 0.1 0.1 15.9 338.4 0.7 28.7 16.0 77.8 58.0 42.4 0.0 21.0 51.0 239.0 3.0 1.0 99.8 122.3 0.4 34.6 187.0 32.6 63.1 0.3 29.6 46.2 15.6 25.0 39.4 0.4 8.6 0.3 25.4 84.0 127.6 29.3 51.3 76.4 46.3 16.8 49.6 38.0 117.2 21.7 34.9 38.2 46.6 61.2 69.4 58.2 78.1 72.1 29.1 34.1 33.7 40.9 27.7 31.3 37.1 32.5 35.7 33.4 33.1 38.7 58.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 0.0 0.0 0.0 0.0 130.2 56.4 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 124.3 59.5 0.0 0.0 0.0 0.0 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 0.0 0.0 0.0 0.0 160.3 6.5 0.0 0.0 0.0 H2BC7 "H2B/g, H2BFG, HIST1H2BF" ENSG00000277224 "H2B clustered histone 7" P62807 6 26199520-26200715 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 7.4" "Cell type enhanced" "Detected in single" "Hofbauer cells: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "U-266/70: 24.8;U-266/84: 18.8" "Low region specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.15e-2)" "unprognostic (2.17e-1)" "unprognostic (1.12e-1)" "unprognostic (1.38e-2)" "unprognostic (4.58e-2)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (6.80e-3)" "unprognostic (3.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.95e-1)" "unprognostic (7.27e-3)" "unprognostic (4.29e-11)" "unprognostic (4.88e-3)" "unprognostic (4.45e-1)" "unprognostic (1.15e-2)" "unprognostic (1.30e-1)" 0.9 0.2 0.6 0.2 1.1 1.2 1.6 4.0 0.9 3.3 1.5 1.4 0.0 0.1 0.0 3.2 1.8 0.2 0.4 0.8 0.6 1.4 0.6 1.7 0.3 1.9 1.7 0.8 0.2 0.0 0.6 0.2 2.4 7.4 0.2 0.6 1.1 0.0 0.0 0.9 0.7 0.0 2.1 2.3 0.7 0.6 1.2 1.7 0.6 0.1 0.4 0.4 4.5 2.4 0.5 0.3 0.2 0.5 0.3 0.0 0.2 0.2 0.1 0.7 0.1 0.7 0.1 0.6 1.0 0.0 0.3 1.0 0.5 0.1 0.3 0.8 0.2 0.4 1.8 0.2 0.1 0.1 0.9 0.3 0.1 0.2 0.1 0.0 0.1 0.5 2.0 4.5 0.0 0.1 4.0 1.6 0.6 0.8 0.6 1.5 0.7 3.0 0.1 0.1 2.4 0.4 4.9 0.9 0.1 0.3 4.4 0.2 0.1 0.3 2.2 0.0 0.6 24.8 18.8 1.3 0.1 1.2 0.5 0.0 0.0 0.6 0.2 0.1 0.6 0.2 0.2 0.3 0.1 1.0 0.2 0.5 2.4 0.2 0.3 0.3 0.2 0.5 0.6 1.1 4.0 0.9 0.8 0.6 1.9 1.7 2.4 2.1 1.2 2.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 H3C4 "H3/b, H3FB, HIST1H3D" ENSG00000197409 "H3 clustered histone 4" P68431 6 26196784-26197286 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.2;brain: 15.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 5.7;MOLT-4: 5.4;U-266/70: 11.7;U-266/84: 6.9" HPA042570 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA042570: AB_2678056" "unprognostic (8.64e-2)" "unprognostic (1.27e-2)" "unprognostic (9.06e-3)" "unprognostic (2.00e-1)" "unprognostic (6.59e-2)" "unprognostic (1.43e-2)" "unprognostic (8.62e-2)" "unprognostic (1.56e-1)" "unprognostic (2.95e-1)" "unprognostic (2.69e-2)" "unprognostic (2.80e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.78e-6)" "unprognostic (2.44e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (4.94e-2)" 0.6 0.8 4.3 0.1 4.1 12.2 0.6 15.9 3.2 2.3 5.7 1.0 0.6 0.2 0.0 2.0 0.9 0.5 0.5 1.1 2.6 0.9 1.5 1.4 0.4 4.8 5.2 0.8 0.2 0.0 0.6 0.2 4.8 2.8 0.0 0.1 1.0 0.1 0.0 0.7 0.7 0.1 6.7 1.7 0.6 0.8 4.5 1.8 0.6 0.0 0.3 0.7 2.8 10.9 1.5 0.0 0.2 1.2 0.8 0.3 0.7 0.0 0.3 1.6 1.1 2.9 0.6 2.7 1.3 0.4 0.0 0.4 0.7 0.1 0.0 1.5 0.2 0.1 1.3 2.0 0.1 0.9 1.8 0.1 0.1 1.2 0.3 0.0 0.5 1.1 1.2 5.7 0.0 0.6 5.4 4.6 0.2 0.1 0.9 2.7 0.3 3.1 0.0 0.0 0.8 0.1 0.0 1.0 0.8 0.0 0.6 1.6 1.4 0.3 2.9 0.0 1.5 11.7 6.9 0.6 1.5 0.3 0.4 14.8 1.6 4.2 3.4 1.6 8.6 8.3 2.5 3.5 3.9 13.0 2.6 4.6 22.2 3.2 3.5 5.1 3.3 0.9 4.3 4.1 15.9 3.2 1.1 2.6 4.8 5.2 4.8 6.7 4.5 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 H4C5 "H4/j, H4FJ, HIST1H4E" ENSG00000276966 "H4 clustered histone 5" P62805 6 26204552-26206038 "Disease related genes, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 69.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.2;Cytotrophoblasts: 2.7;dendritic cells: 1.8;Extravillous trophoblasts: 1.6;Hofbauer cells: 4.6;Plasma cells: 1.3;Syncytiotrophoblasts: 3.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 69.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 6.1;U-266/70: 11.3" HPA042201 Supported NA NA 25000000 "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA042201: AB_2677898" "unprognostic (8.62e-2)" "unprognostic (4.86e-2)" "unprognostic (5.71e-3)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" "unprognostic (5.08e-3)" "unprognostic (7.99e-2)" "unprognostic (1.21e-1)" "unprognostic (6.57e-2)" "unprognostic (2.34e-3)" "unprognostic (4.34e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (1.28e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" 0.8 0.5 12.1 0.4 14.5 2.1 0.8 69.4 14.4 3.8 0.5 1.9 0.9 0.5 0.8 2.6 2.7 0.2 1.1 10.8 8.1 3.1 1.0 1.0 0.5 3.9 3.2 2.8 0.5 0.2 2.2 0.5 6.9 7.5 0.5 1.5 1.3 0.3 0.0 1.9 0.9 0.2 15.2 1.5 1.6 2.0 7.2 1.9 1.5 0.0 0.4 0.6 3.6 16.8 1.1 0.7 1.3 3.1 0.5 0.0 0.7 1.1 0.3 0.5 0.4 0.4 1.1 0.4 1.5 0.3 0.7 1.9 0.7 0.1 0.7 0.9 0.8 0.3 1.5 0.7 0.0 0.5 1.2 0.3 0.0 0.4 0.3 0.3 0.4 1.0 2.3 2.6 0.1 0.4 6.1 2.8 1.3 0.5 1.0 2.7 1.4 2.7 0.5 0.4 3.7 0.9 0.8 1.3 0.4 0.4 1.2 0.5 0.5 1.5 2.1 0.4 0.9 11.3 4.7 1.7 0.3 1.1 1.1 2.7 2.1 1.8 2.0 1.8 2.9 2.5 3.0 2.0 3.1 5.4 3.2 2.6 2.6 2.3 5.5 2.7 2.0 1.2 12.1 14.5 69.4 14.4 10.8 8.1 3.9 3.2 6.9 15.2 7.2 16.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 2.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.2 0.0 0.0 0.0 HAS3 ENSG00000103044 "Hyaluronan synthase 3" O00219 16 69105653-69118719 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.5;urinary bladder: 92.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.3;Basal prostatic cells: 51.6;Basal respiratory cells: 107.1;Suprabasal keratinocytes: 158.6;Urothelial cells: 115.5" "Group enriched" "Detected in many" 8 "cervical cancer: 17.1;head and neck cancer: 44.9;lung cancer: 23.3;urothelial cancer: 31.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 52.5;PC-3: 270.5;RT4: 111.6" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA031554, CAB033850" Supported Approved Microtubules NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 28: Keratinocytes - Keratinization" Microtubules "CAB033850: AB_2116418, HPA031554: AB_10670703" "unprognostic (3.26e-2)" "unprognostic (1.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (7.59e-3)" "unprognostic (2.86e-3)" "unprognostic (1.84e-1)" "unprognostic (3.70e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (2.46e-1)" "unprognostic (3.27e-3)" "unprognostic (3.25e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (3.40e-3)" 0.8 0.5 0.9 0.7 1.2 0.9 7.5 1.3 1.3 4.6 0.9 5.3 2.9 0.9 1.1 33.5 1.2 4.8 0.7 0.6 1.1 1.1 1.3 20.1 0.4 1.0 1.3 1.4 1.3 0.4 1.7 3.4 1.1 3.7 3.1 0.8 5.4 1.5 1.2 9.7 2.2 0.6 0.4 0.8 12.8 3.5 1.0 0.5 5.9 0.9 2.8 92.8 10.3 1.0 3.5 17.1 1.0 0.9 0.3 0.4 6.6 1.1 0.4 1.0 0.4 3.4 9.0 0.7 2.0 0.4 4.0 52.5 2.9 31.5 1.0 0.2 1.3 0.0 0.2 0.6 0.1 0.3 0.9 0.5 8.6 1.0 3.0 4.0 0.7 0.6 0.1 0.4 0.3 1.8 1.2 0.7 15.5 18.7 270.5 2.0 0.1 0.2 28.3 111.6 19.2 0.8 1.8 0.1 0.3 3.1 0.6 0.8 0.3 0.9 0.9 29.9 1.8 1.0 0.9 0.2 1.0 0.0 0.6 0.1 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.9 1.2 1.3 1.3 0.6 1.1 1.0 1.3 1.1 0.4 1.0 1.0 4.2 0.0 30.8 0.7 0.2 162.3 51.6 107.1 8.6 1.1 1.6 6.1 1.4 0.0 12.2 0.0 2.1 1.0 0.1 16.4 0.0 4.5 10.2 0.7 0.3 2.4 0.0 0.4 1.0 3.6 0.9 1.1 5.1 2.7 0.0 0.4 1.1 0.2 0.3 0.0 2.1 0.7 2.0 0.0 6.5 22.7 1.2 0.5 3.6 0.0 0.0 0.1 0.0 0.5 0.8 2.4 0.2 0.4 0.6 18.4 0.1 0.7 3.0 1.0 0.0 0.9 1.9 0.5 0.7 25.6 158.6 0.3 1.1 0.1 2.2 115.5 HCAR1 "FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR" ENSG00000196917 "Hydroxycarboxylic acid receptor 1" Q9BXC0 12 122726076-122730844 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 11.5;parathyroid gland: 40.4" "Group enriched" "Detected in some" 4 "Breast glandular cells: 8.7;Breast myoepithelial cells: 5.2;Club cells: 3.2;Early spermatids: 9.6;Extravillous trophoblasts: 3.7;Late spermatids: 6.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;MCF7: 8.1;RT4: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "prognostic unfavorable (3.61e-5)" "unprognostic (8.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-2)" "unprognostic (3.80e-4)" "unprognostic (5.43e-4)" "unprognostic (1.41e-1)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (2.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.38e-1)" "unprognostic (1.87e-2)" 5.5 0.3 0.4 0.2 0.4 1.0 11.5 1.7 0.7 0.7 0.4 0.1 0.3 0.4 1.2 0.2 1.7 0.2 0.2 0.6 0.1 0.8 0.1 0.4 0.4 0.3 0.1 0.4 0.1 40.4 0.3 1.0 0.3 1.0 0.1 0.6 5.0 5.1 1.2 0.7 0.3 0.2 0.1 2.3 2.0 0.8 0.2 0.3 1.3 0.1 0.1 1.2 0.3 1.2 0.1 0.3 0.2 0.3 0.0 0.0 1.9 0.1 0.0 0.0 0.1 2.5 12.1 0.3 0.4 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.6 1.8 0.2 0.3 0.2 0.6 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.6 0.1 8.1 0.2 0.4 0.3 3.0 0.6 0.3 0.2 0.3 0.1 35.3 2.6 0.2 0.1 4.2 0.0 0.3 3.4 0.1 0.3 0.4 0.2 0.2 0.2 0.4 0.1 0.4 0.2 0.2 0.3 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.1 0.1 0.4 0.4 1.7 0.7 0.6 0.1 0.3 0.1 0.3 0.1 0.2 1.2 1.3 0.0 0.5 0.0 0.0 0.1 1.4 0.2 0.0 0.3 8.7 5.2 0.4 0.0 3.2 0.0 0.0 0.4 0.3 0.0 0.0 0.0 9.6 0.2 0.2 0.3 0.0 0.0 0.0 0.0 3.7 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 6.5 0.3 0.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.1 1.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 1.0 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" 96.3 89.7 95.9 72.8 98.8 305.3 90.6 98.4 113.4 91.4 98.0 109.2 130.2 77.6 70.0 186.3 112.8 62.5 119.0 92.8 95.1 135.4 222.3 113.5 64.6 106.3 99.7 86.8 93.2 92.8 67.8 71.8 98.8 81.7 118.1 68.9 96.6 56.8 234.9 155.3 128.4 70.5 100.8 77.2 99.1 42.6 99.6 157.2 90.7 132.5 114.9 106.7 102.7 105.7 491.5 249.1 258.2 125.6 150.0 203.0 296.8 158.4 406.3 366.8 234.4 279.4 500.9 335.5 310.6 325.0 158.6 338.8 408.9 365.0 356.0 276.1 299.9 278.1 339.4 241.2 202.0 411.9 227.4 152.4 335.7 292.8 560.4 278.6 272.4 249.6 387.0 260.4 293.7 369.3 345.5 459.2 472.1 755.4 347.7 384.8 156.9 435.1 401.0 162.6 396.9 432.0 380.4 480.3 199.3 319.8 387.6 621.9 242.4 181.1 286.5 230.3 408.9 364.0 486.0 555.6 238.9 318.4 235.2 6.2 9.9 9.2 6.6 8.8 4.9 5.6 5.6 5.9 11.6 6.6 5.0 4.7 5.6 5.2 10.0 11.9 8.2 6.8 95.9 98.8 98.4 113.4 92.8 95.1 106.3 99.7 98.8 100.8 99.6 105.7 51.9 70.5 99.2 12.1 35.3 147.3 185.1 90.5 76.2 66.7 89.9 66.0 91.0 98.7 75.3 71.7 27.1 44.1 72.4 121.4 80.3 112.2 48.4 144.0 79.2 66.1 124.6 217.8 12.0 132.0 107.3 66.7 62.7 91.8 30.4 67.4 35.0 164.5 52.7 53.8 12.4 104.3 48.8 45.6 89.1 47.0 40.7 71.0 39.2 14.0 57.3 71.4 25.7 5.5 16.1 165.7 59.5 45.9 59.0 281.3 138.2 118.1 126.8 34.9 19.7 70.9 57.8 27.7 28.3 108.6 159.4 54.9 50.5 83.2 114.9 228.6 HEATR9 "C17orf66, FLJ32830" ENSG00000270379 "HEAT repeat containing 9" A2RTY3 17 35854946-35868891 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 10.1" "Group enriched" "Detected in some" 17 "Early spermatids: 88.4;Late spermatids: 36.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA023129 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA023129: AB_1845599" "unprognostic (1.02e-1)" "unprognostic (2.63e-3)" "unprognostic (5.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (7.44e-4)" "unprognostic (1.30e-3)" "unprognostic (2.43e-2)" "unprognostic (2.63e-1)" "unprognostic (3.28e-1)" "unprognostic (1.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.61e-10)" "unprognostic (6.78e-2)" "unprognostic (1.93e-1)" "unprognostic (4.52e-2)" "unprognostic (5.61e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 88.4 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.3 0.0 36.4 0.6 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 HECW1 "KIAA0322, NEDL1" ENSG00000002746 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1" Q76N89 7 43112629-43566001 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 135.6;Excitatory neurons: 533.3;Inhibitory neurons: 157.3;Late spermatids: 72.0;Oligodendrocyte precursor cells: 277.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "cerebral cortex: 16.4" "Group enriched" "Detected in some" 4 "basophil: 4.9;neutrophil: 3.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 4.9" "Cell line enhanced" "Detected in some" "A549: 3.8;GAMG: 3.7;U-266/70: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007203, HPA007593, HPA007609" Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA007203: AB_2667776, HPA007593: AB_1852305, HPA007609: AB_2117518" "unprognostic (1.40e-1)" "unprognostic (2.85e-3)" "unprognostic (2.57e-1)" "unprognostic (4.39e-1)" "unprognostic (2.43e-2)" "unprognostic (2.80e-2)" "unprognostic (8.65e-4)" "unprognostic (6.93e-2)" "unprognostic (7.30e-2)" "unprognostic (7.31e-2)" "unprognostic (3.43e-2)" "unprognostic (2.67e-2)" "unprognostic (1.43e-3)" "unprognostic (1.64e-2)" "unprognostic (5.23e-3)" "unprognostic (1.89e-2)" "unprognostic (2.42e-2)" 0.1 0.0 1.5 0.2 1.7 0.5 0.2 0.0 16.4 0.1 0.0 0.2 0.0 0.2 0.6 1.0 0.1 1.9 0.0 0.7 0.0 7.8 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.3 0.1 2.2 0.4 0.2 0.9 0.6 0.1 0.1 0.0 0.1 0.3 1.8 0.2 0.0 0.5 2.6 0.2 0.3 0.1 3.8 0.0 3.8 0.3 0.5 0.0 0.0 0.0 1.2 2.2 0.1 0.5 0.0 0.0 0.2 2.3 2.2 3.7 0.2 0.0 0.0 0.2 0.1 0.7 0.0 0.3 0.2 0.2 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.3 0.0 0.0 0.0 0.0 1.8 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.8 0.9 0.3 12.0 0.4 0.0 2.7 0.3 0.0 4.9 0.8 0.7 0.3 0.5 0.2 0.6 0.3 0.1 0.1 1.0 0.3 0.3 3.3 0.6 0.6 0.9 0.1 0.0 1.5 1.7 0.0 16.4 0.7 0.0 0.2 0.0 0.1 0.0 0.2 3.8 0.0 0.0 0.0 7.8 0.1 0.4 0.3 0.0 0.0 15.4 0.1 0.3 1.4 0.0 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 135.6 1.1 3.6 0.2 0.0 0.0 533.3 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.4 0.1 0.0 45.4 157.3 0.1 0.0 0.0 1.4 72.0 0.3 0.2 0.0 24.4 0.1 0.6 0.0 277.9 4.8 0.0 1.4 0.4 0.0 0.4 4.3 15.8 0.0 1.9 0.0 0.6 0.4 3.2 3.3 0.3 0.3 0.0 0.6 0.2 0.5 0.3 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 200.3;liver: 752.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Endometrial ciliated cells: 113.9;Glandular and luminal cells: 127.8;Hepatocytes: 534.7;Proximal tubular cells: 477.5" "Cancer enriched" "Detected in many" 4 "liver cancer: 119.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cell line enhanced" "Detected in some" "CACO-2: 55.8;EFO-21: 82.7;Hep G2: 186.6;OE19: 328.0;RPTEC TERT1: 212.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.2" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA047374: AB_2680019, HPA052359: AB_2681798" "unprognostic (1.36e-1)" "unprognostic (9.89e-2)" "unprognostic (3.93e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (5.65e-3)" "unprognostic (7.20e-2)" "unprognostic (6.05e-2)" "unprognostic (2.41e-3)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (4.29e-3)" "unprognostic (8.57e-2)" "unprognostic (1.78e-1)" "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" 0.4 0.3 0.4 2.5 1.9 0.5 12.5 0.6 0.8 27.4 1.5 16.7 31.6 3.1 13.0 0.4 4.2 61.7 0.3 0.5 0.4 200.3 752.6 0.8 0.4 0.4 0.4 0.2 31.2 7.0 0.2 0.2 0.4 44.5 20.3 0.7 4.2 4.2 0.1 0.9 25.6 0.5 0.4 0.6 25.5 0.1 0.5 0.7 55.1 0.2 0.1 0.2 0.1 0.6 0.0 12.3 4.6 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 55.8 10.7 0.1 82.7 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.2 186.6 0.0 0.4 1.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.3 0.5 0.0 0.0 0.2 0.3 328.0 0.0 0.1 0.3 0.1 212.2 0.0 0.2 0.2 0.2 0.9 0.0 0.0 0.2 1.0 0.6 0.1 0.9 0.2 0.1 0.0 0.3 0.5 0.2 0.8 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.3 0.4 1.9 0.6 0.8 0.5 0.4 0.4 0.4 0.4 0.4 0.5 0.6 0.1 0.0 2.0 0.3 5.9 0.0 0.4 0.6 0.0 0.3 7.5 1.7 0.3 81.5 4.9 27.6 2.1 0.0 0.3 18.5 103.7 7.2 0.2 113.9 17.1 1.2 43.8 24.0 3.2 17.8 0.0 0.4 19.4 127.8 1.3 0.0 16.4 534.7 0.2 0.0 0.6 16.0 2.0 16.1 0.0 0.0 0.0 21.3 0.0 1.9 2.0 4.2 0.0 0.0 0.5 12.1 35.6 0.0 0.0 12.9 54.6 477.5 4.1 0.2 0.0 0.2 1.1 0.1 0.0 0.0 0.0 0.0 3.8 0.4 9.1 0.4 HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 111.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 71.4;Intestinal goblet cells: 89.5;Paneth cells: 87.8;Proximal enterocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 115.9;OE19: 99.2;SH-SY5Y: 56.7;SK-BR-3: 172.6;T-47d: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" 13.2 5.8 21.7 6.6 26.9 2.0 23.2 41.5 33.3 19.9 2.8 17.9 39.1 11.9 29.1 5.5 19.0 21.6 12.4 22.0 24.3 12.3 4.4 20.4 5.3 27.4 22.7 3.0 111.2 14.4 44.0 20.1 30.3 36.2 17.9 8.7 86.2 20.2 4.6 7.6 27.3 6.3 10.4 16.7 68.7 6.8 25.4 2.8 16.8 5.7 6.3 12.3 7.6 39.1 5.2 11.4 1.3 15.8 0.0 0.0 2.7 0.0 0.6 1.1 1.0 10.6 5.8 0.0 1.0 0.0 1.4 4.9 14.5 1.0 0.8 0.0 11.4 0.1 0.3 10.1 2.7 0.0 1.1 0.2 6.0 0.1 2.4 0.3 26.0 3.8 0.7 4.0 0.0 115.9 0.7 0.2 0.4 99.2 7.1 0.2 0.0 21.8 14.5 44.8 21.1 56.7 0.0 172.6 0.0 3.6 101.2 0.0 0.5 0.1 1.4 0.4 0.0 2.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.9 0.7 0.0 0.1 1.0 1.1 0.0 0.0 0.0 2.6 0.0 0.4 21.7 26.9 41.5 33.3 22.0 24.3 27.4 22.7 30.3 10.4 25.4 39.1 21.4 0.0 5.5 4.9 4.6 1.5 2.6 3.1 0.6 14.3 20.4 12.3 3.8 4.3 8.6 0.0 0.0 26.3 1.1 16.0 3.9 19.0 0.4 10.2 3.0 19.1 35.3 0.0 16.1 26.9 1.7 1.0 71.4 20.3 0.0 1.1 20.7 0.4 2.5 20.2 15.5 89.5 16.2 0.8 0.4 1.0 0.9 0.7 7.2 6.5 0.6 2.8 0.0 8.0 50.9 22.9 87.8 0.0 22.7 17.8 107.4 0.5 6.5 4.4 0.0 1.5 1.8 0.4 2.1 0.5 0.4 35.0 1.8 0.1 15.6 13.9 HIGD2A "MGC2198, RCF1B" ENSG00000146066 "HIG1 hypoxia inducible domain family member 2A" Q9BW72 5 176388751-176389761 "Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042715 Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 32: Non-specific - Translation" Mitochondria Cytosol "HPA042715: AB_2678127" "unprognostic (9.24e-2)" "unprognostic (6.31e-3)" "unprognostic (7.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (2.39e-1)" "unprognostic (3.19e-1)" "unprognostic (1.98e-2)" "unprognostic (3.11e-3)" "unprognostic (9.56e-2)" "unprognostic (2.39e-2)" "unprognostic (1.45e-1)" "unprognostic (8.09e-2)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" 146.1 175.6 143.3 87.0 146.2 133.1 113.5 147.2 175.0 104.7 168.0 199.4 118.9 111.7 51.3 130.0 105.0 80.5 318.7 139.8 146.0 182.7 163.3 95.7 132.9 143.9 142.2 118.7 108.7 204.9 125.1 54.6 141.6 127.9 96.3 45.5 163.2 92.7 422.5 140.8 136.6 68.1 145.3 129.3 148.6 66.0 149.0 110.7 114.0 297.9 92.7 152.3 105.2 145.7 104.9 166.6 99.0 172.6 98.5 186.4 262.2 66.6 109.7 164.7 206.4 176.0 202.2 183.3 149.9 107.1 214.2 127.3 146.2 260.6 65.9 424.0 234.0 92.6 161.7 244.7 137.4 149.7 230.1 238.2 213.2 93.7 113.3 126.3 141.7 146.5 104.0 341.5 124.0 315.9 165.3 178.1 124.8 195.5 181.7 157.1 75.6 324.7 265.5 158.7 107.9 141.5 71.4 295.2 310.5 100.7 173.3 233.7 96.8 118.5 124.7 110.2 142.5 165.2 216.6 158.4 150.5 254.1 77.5 284.2 743.6 219.8 391.2 975.8 389.5 618.1 540.1 452.6 930.0 496.0 488.1 464.2 124.6 308.0 1024.9 616.8 621.8 971.3 143.3 146.2 147.2 175.0 139.8 146.0 143.9 142.2 141.6 145.3 149.0 145.7 100.4 73.7 78.6 0.0 212.5 232.2 332.8 358.0 272.0 60.5 225.5 288.5 145.3 174.5 191.0 182.1 12.5 223.0 184.2 415.6 534.1 204.5 83.9 140.0 120.6 110.9 266.6 90.8 0.0 237.3 185.4 129.1 142.2 124.2 130.0 157.0 120.3 217.0 378.7 65.6 0.0 450.7 219.7 458.8 345.2 56.8 140.1 292.1 257.9 0.0 449.7 138.1 230.7 0.0 0.0 110.0 493.0 85.0 184.2 292.6 313.8 542.8 142.3 47.7 118.3 145.9 138.8 96.7 79.4 301.8 225.0 280.2 223.7 182.1 385.3 532.4 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HK3 ENSG00000160883 "Hexokinase 3" P52790 5 176880869-176899346 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 129.3;lymphoid tissue: 76.6" "Group enriched" "Detected in some" 13 "Early spermatids: 11.1;Hofbauer cells: 34.5;Kupffer cells: 43.9;Macrophages: 38.8;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 7 "cerebellum: 1.4;cerebral cortex: 1.6;thalamus: 2.4" "Immune cell enhanced" "Detected in many" "basophil: 569.7" "Group enriched" "Detected in many" 13 "granulocytes: 569.7;monocytes: 200.9" "Cell line enriched" "Detected in some" 5 "U-937: 20.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA056743 Enhanced NA NA 2000000 "Cluster 10: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA056743: AB_2683222" "unprognostic (4.22e-2)" "unprognostic (4.07e-2)" "unprognostic (1.23e-1)" "unprognostic (8.63e-2)" "unprognostic (2.02e-2)" "unprognostic (1.39e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (3.82e-1)" "prognostic unfavorable (3.84e-8)" "unprognostic (7.02e-2)" "unprognostic (6.01e-3)" "unprognostic (1.46e-1)" "unprognostic (5.42e-2)" 8.4 4.5 0.0 19.0 0.2 129.3 2.6 1.4 1.6 0.8 0.2 2.5 2.0 1.0 0.1 0.9 5.1 2.1 4.0 0.2 0.0 1.8 5.2 25.1 4.2 0.0 0.0 1.0 1.5 0.1 0.7 2.8 0.0 1.1 1.4 0.1 1.5 0.3 0.9 0.5 3.1 7.9 0.0 76.6 2.1 1.3 2.4 1.4 1.3 0.5 0.7 4.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.5 0.1 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.6 0.0 569.7 92.5 204.8 0.3 179.4 0.2 0.4 0.2 0.1 30.2 0.2 0.1 0.1 32.2 0.2 200.9 1.4 0.2 43.6 0.0 0.2 1.4 1.6 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.4 1.3 0.0 0.4 0.2 34.5 0.0 0.4 0.0 0.0 43.9 0.9 1.8 0.0 38.8 0.0 1.0 14.6 0.0 2.1 0.0 0.1 0.1 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.0 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 20.3" "Cell type enhanced" "Detected in many" "Adipocytes: 33.8;Endothelial cells: 21.4;Fibroblasts: 22.2;Horizontal cells: 26.9;Microglial cells: 45.0" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 22.3;hTERT-RPE1: 20.1;MCF7: 76.5;SK-MEL-30: 50.2;WM-115: 43.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 9.9" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 9200000 "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" 9.7 1.4 1.3 0.6 1.2 0.0 8.4 0.9 1.1 3.7 1.3 9.0 0.9 1.9 2.5 5.4 1.8 6.5 8.4 0.8 1.1 2.5 7.8 20.3 0.4 1.5 1.9 3.9 0.9 0.9 3.2 4.8 1.5 7.5 2.8 0.6 7.7 1.4 4.8 4.1 3.1 4.3 1.4 8.4 1.7 2.6 1.7 0.8 3.2 7.0 2.4 1.8 3.8 0.9 0.2 0.1 1.6 0.0 4.7 4.7 0.0 0.5 0.9 0.3 0.5 0.0 0.1 1.9 0.2 22.3 1.6 5.0 0.1 0.2 0.1 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 4.7 0.0 5.6 0.4 20.1 2.8 0.0 0.2 0.0 0.0 76.5 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 50.2 4.5 0.1 0.0 0.0 13.7 1.3 0.0 5.1 0.2 0.0 0.3 2.7 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.3 1.2 0.9 1.1 0.8 1.1 1.5 1.9 1.5 1.4 1.7 0.9 33.8 3.2 7.0 0.3 0.0 3.2 0.2 4.9 2.2 1.7 1.2 1.8 2.8 0.0 0.8 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.3 0.6 1.5 21.4 0.0 0.0 1.1 0.0 0.8 22.2 0.0 0.9 0.0 5.2 7.9 1.9 0.1 26.9 3.8 0.0 0.0 0.3 2.8 2.7 3.7 0.4 5.4 45.0 0.0 0.1 0.0 3.0 1.5 0.0 0.0 2.2 1.2 0.1 0.0 0.2 1.0 0.0 0.0 2.5 7.7 0.5 0.1 0.4 1.7 0.0 0.4 0.1 0.0 0.2 HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 327.2;Hepatocytes: 1118.3;Intestinal goblet cells: 226.8;Paneth cells: 177.7;Undifferentiated cells: 282.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 441.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 113.6;RT4: 201.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 830000 "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "CAB032906: AB_2118322, HPA027423: AB_2672266, HPA027442: AB_2672277" "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" "unprognostic (7.62e-2)" "unprognostic (1.49e-2)" "prognostic favorable (2.43e-7)" "unprognostic (9.68e-2)" "unprognostic (3.21e-2)" "prognostic favorable (2.17e-4)" "unprognostic (1.20e-1)" "unprognostic (6.42e-2)" "prognostic favorable (3.43e-5)" "unprognostic (9.57e-2)" "unprognostic (2.31e-1)" "unprognostic (5.00e-2)" "unprognostic (1.54e-3)" 1.0 0.3 0.0 7.3 0.0 0.0 222.4 0.0 0.0 0.1 5.2 366.7 165.6 1.4 0.4 4.3 0.4 4.3 36.6 0.0 0.1 64.9 2434.1 2.2 0.1 0.0 0.1 0.1 20.1 0.1 0.1 0.4 0.0 34.0 228.0 0.1 50.8 0.6 6.9 14.2 151.8 23.7 0.0 0.6 101.2 35.6 0.0 0.4 0.6 3.1 0.0 36.5 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 12.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 113.6 0.1 0.2 0.7 0.7 0.0 201.6 0.1 0.8 0.6 0.0 0.0 0.1 7.6 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 10.8 0.0 2.4 0.1 3.7 0.0 1.2 0.0 18.8 5.6 8.7 42.9 0.1 31.3 0.0 0.8 0.0 327.2 0.0 0.0 1.9 0.6 0.1 1.1 73.1 24.0 0.0 0.0 0.2 0.2 66.8 1.4 4.5 19.5 16.4 1118.3 0.2 0.0 0.0 226.8 0.0 26.1 0.7 3.9 1.5 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 177.7 0.0 0.0 6.3 12.4 0.9 0.0 0.0 6.6 0.0 0.1 0.4 0.5 1.9 0.3 9.4 2.2 0.1 282.3 26.5 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HOMER2 "CPD, Cupidin, DFNA68, HOMER-2, HOMER-2A, HOMER-2B, Vesl-2" ENSG00000103942 "Homer scaffold protein 2" Q9NSB8 15 82836946-82986153 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 226.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 215.9;Endometrial ciliated cells: 184.4;Glandular and luminal cells: 151.9" "Cancer enhanced" "Detected in many" "prostate cancer: 15.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 52.7;Karpas-707: 92.6;SCLC-21H: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040134, CAB079014" Uncertain Supported Supported Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "CAB079014: , HPA040134: AB_10795272" "unprognostic (7.34e-2)" "unprognostic (3.58e-2)" "unprognostic (5.75e-4)" "unprognostic (3.31e-3)" "unprognostic (4.85e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-2)" "unprognostic (7.13e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-1)" "unprognostic (8.16e-4)" "unprognostic (2.30e-1)" "unprognostic (3.21e-2)" "unprognostic (1.26e-1)" "unprognostic (4.45e-3)" 1.5 6.3 6.5 1.1 7.6 4.6 26.9 8.2 12.8 23.1 69.8 3.2 8.5 8.4 33.7 21.2 25.9 12.8 21.9 16.2 7.8 7.2 46.4 5.3 1.3 5.7 4.6 2.6 226.2 5.1 7.7 0.6 5.7 57.7 1.0 6.4 71.2 4.6 108.7 45.0 1.3 1.4 4.1 4.8 55.4 6.1 6.0 3.0 28.9 55.9 3.6 1.3 11.7 8.0 16.6 6.9 7.2 18.9 0.2 0.1 1.1 1.1 0.0 1.7 0.6 1.2 11.5 0.1 8.8 8.4 8.3 9.1 52.7 24.9 1.2 45.1 33.5 10.6 0.4 8.3 0.7 0.4 32.6 1.8 37.4 0.6 2.1 1.9 0.0 20.6 0.4 92.6 7.0 48.4 3.2 1.1 11.4 1.4 5.1 2.2 11.5 5.5 25.3 20.1 50.8 13.1 18.6 14.1 17.6 5.2 17.1 3.5 0.2 17.2 31.7 1.3 15.3 11.8 5.9 1.8 29.0 0.4 6.4 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.3 0.1 0.0 0.4 0.0 0.0 0.5 0.2 0.3 6.5 7.6 8.2 12.8 16.2 7.8 5.7 4.6 5.7 4.1 6.0 8.0 1.9 16.0 10.1 24.8 3.8 4.6 56.1 7.2 10.2 15.0 39.7 20.4 23.0 215.9 14.6 11.0 18.8 1.1 4.4 0.3 7.9 29.6 1.9 184.4 15.4 12.4 3.0 8.2 24.8 76.5 0.4 3.6 14.3 151.9 0.0 11.9 1.4 59.6 13.3 20.2 35.1 0.4 0.0 3.2 73.9 4.0 1.8 9.2 37.4 7.5 7.9 18.5 1.0 6.6 11.8 25.9 0.1 0.7 4.1 81.5 0.7 12.1 4.0 5.1 0.0 7.8 4.8 5.5 16.6 19.4 6.0 0.7 3.1 4.1 0.4 30.5 HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 5.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Distal tubular cells: 1.9;Melanocytes: 3.6;Proximal enterocytes: 3.7;Spermatocytes: 3.5;Suprabasal keratinocytes: 3.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 34.7;BJ hTERT+: 17.5;HaCaT: 15.4;HeLa: 12.4;T-47d: 27.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "spinal cord: 1.3" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 6: T47d - Mammary gland" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 1.8 5.0 1.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 9.3 1.1 0.0 34.7 3.2 4.9 0.0 5.1 17.5 7.4 5.3 0.3 1.3 0.0 0.3 4.8 0.0 15.4 6.6 0.0 3.3 1.0 0.1 0.2 12.4 0.0 0.0 0.1 0.1 0.9 1.4 0.0 0.4 0.0 0.0 0.3 1.5 0.0 4.8 2.2 0.0 0.1 0.0 10.1 0.1 0.0 0.6 0.0 0.7 1.2 0.0 0.2 3.2 7.8 3.1 0.3 27.4 0.0 0.0 0.0 5.8 0.4 0.3 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.9 0.0 0.0 0.0 1.0 1.0 3.5 0.9 0.0 3.8 0.0 0.1 0.0 0.2 0.0 HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.7;Breast myoepithelial cells: 3.0;Spermatogonia: 1.2;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 31.2;HaCaT: 66.1;SK-BR-3: 36.0;T-47d: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA051634 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.7 10.5 0.0 31.2 0.5 0.0 18.4 1.9 4.4 2.8 1.5 2.7 0.5 0.0 0.4 0.0 2.0 66.1 8.0 2.1 1.6 0.0 6.4 0.0 8.4 0.0 0.0 0.0 6.6 0.0 15.4 0.0 6.0 0.0 0.0 0.1 11.8 0.0 11.5 20.1 0.0 0.0 0.3 6.6 2.7 0.0 0.4 0.0 0.0 6.0 0.0 0.0 10.4 36.0 4.9 7.4 28.1 0.1 0.0 0.1 13.1 0.2 4.2 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.7 3.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.2 0.0 2.4 0.1 0.0 0.0 0.0 0.0 HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.0" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 9.1;Endometrial ciliated cells: 12.3;Granulosa cells: 10.5;Sertoli cells: 6.6;Squamous epithelial cells: 8.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "medulla oblongata: 16.7;pons: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 23.8;HDLM-2: 31.2;HEK 293: 33.0;SH-SY5Y: 27.3" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 49 "medulla oblongata: 4.9;pons: 3.7;spinal cord: 6.0" HPA053910 Supported Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" 8.6 4.5 0.1 2.1 0.1 0.1 5.2 0.1 0.2 1.0 0.1 2.1 1.1 4.7 7.2 8.1 27.0 0.4 0.5 0.2 0.2 13.5 0.1 0.8 3.6 16.7 1.1 11.1 0.3 0.1 0.1 6.3 16.2 1.6 0.2 0.0 0.3 0.9 9.1 6.2 6.8 4.8 6.4 1.8 5.2 3.3 0.3 0.4 1.0 0.0 1.9 0.7 0.8 3.7 5.3 5.1 0.0 23.8 9.4 4.9 0.0 2.4 2.5 2.4 1.7 0.2 4.3 20.5 0.2 18.5 0.1 4.7 0.4 0.6 1.5 31.2 33.0 0.2 2.9 0.0 1.1 2.5 0.7 12.5 2.3 13.7 2.4 0.0 0.3 6.7 1.1 0.0 8.9 0.3 2.8 0.5 0.1 0.9 0.1 6.7 7.2 0.0 10.2 0.0 0.0 27.3 3.8 1.2 13.7 1.1 18.0 1.2 0.0 12.0 6.9 1.0 12.8 5.3 6.0 10.6 0.7 2.3 12.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.2 16.7 1.1 16.2 6.4 0.3 3.7 1.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 9.1 0.0 1.4 3.4 0.5 0.0 0.0 0.0 0.0 0.1 3.9 0.0 1.9 0.0 4.1 12.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 2.6 0.1 0.0 10.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.8 0.0 2.9 3.1 0.2 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.1 0.0 1.5 3.7 0.0 0.1 2.9 0.0 0.0 6.6 3.9 3.6 2.7 0.5 8.2 0.0 0.3 1.6 2.7 0.1 0.0 HPD "4-HPPD, 4HPPD, GLOD3, PPD" ENSG00000158104 "4-hydroxyphenylpyruvate dioxygenase" P32754 12 121839527-121863596 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2530.4" "Group enriched" "Detected in some" 9 "Hepatocytes: 1373.6;Proximal tubular cells: 2144.0" "Cancer enriched" "Detected in many" 100 "liver cancer: 540.9" "Region enhanced" "Detected in many" "hippocampal formation: 7.8" "Immune cell enhanced" "Detected in some" "eosinophil: 7.8" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;granulocytes: 7.8" "Cell line enriched" "Detected in some" 31 "Hep G2: 516.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038321, HPA038322" Enhanced Uncertain "Nuclear speckles" NA NA 26000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA038321: AB_2675957, HPA038322: AB_10670778" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.81e-3)" "unprognostic (1.42e-3)" "unprognostic (1.10e-2)" "unprognostic (9.08e-2)" "unprognostic (1.13e-2)" "unprognostic (8.84e-2)" "unprognostic (5.58e-2)" "unprognostic (6.14e-3)" "unprognostic (9.72e-3)" "unprognostic (8.61e-3)" "unprognostic (7.16e-2)" "unprognostic (1.97e-1)" "unprognostic (4.12e-1)" "unprognostic (3.06e-2)" "unprognostic (2.34e-1)" 2.3 5.3 0.6 0.7 0.4 0.9 4.6 3.2 0.6 2.0 119.0 1.2 0.1 4.1 0.7 0.7 6.4 1.1 3.5 7.8 0.5 531.0 2530.4 2.0 0.3 1.5 1.0 4.7 3.9 0.1 1.1 0.3 0.8 2.3 0.5 0.3 0.2 7.3 2.2 0.2 0.9 1.4 0.6 2.3 1.9 10.2 3.5 0.1 0.7 0.1 0.1 3.7 1.9 1.0 0.3 0.9 0.6 0.6 0.3 0.6 0.6 0.0 0.1 0.0 0.0 0.2 0.5 0.2 0.6 1.1 0.2 0.4 0.2 0.0 0.0 0.3 0.8 1.2 5.4 516.4 11.5 1.8 16.4 3.6 0.3 0.0 0.0 1.3 0.0 0.5 0.8 0.0 1.3 1.3 0.2 0.4 9.9 0.4 0.0 0.3 1.6 0.5 0.0 1.4 0.1 0.1 1.5 0.1 0.1 6.9 1.1 0.9 0.2 0.0 0.3 0.1 0.1 0.8 0.6 0.7 0.2 1.2 0.0 0.0 0.6 7.8 0.0 0.8 0.0 0.1 0.1 0.1 1.0 0.1 0.2 0.2 3.9 0.0 1.3 3.8 0.0 0.3 0.6 0.4 3.2 0.6 7.8 0.5 1.5 1.0 0.8 0.6 3.5 1.0 0.0 0.0 0.0 0.7 15.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 55.8 0.0 92.0 0.0 0.8 0.0 0.0 193.7 0.5 38.0 0.1 0.0 2.6 0.0 80.2 1.0 16.2 0.3 0.4 0.0 0.1 0.0 0.0 38.9 1373.6 0.3 0.0 1.0 0.0 0.0 37.8 0.3 121.0 2.5 10.8 0.0 0.0 0.4 0.0 0.0 1.5 0.7 0.2 0.0 5.3 0.0 0.0 0.0 2144.0 0.0 0.0 0.0 2.0 0.2 1.8 1.4 0.0 0.0 1.1 8.0 7.1 0.0 0.0 HPN TMPRSS1 ENSG00000105707 Hepsin P05981 19 35040506-35066573 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 200.5;liver: 866.2;pancreas: 272.1" "Group enriched" "Detected in many" 6 "Hepatocytes: 442.2;Proximal tubular cells: 201.0" "Cancer enhanced" "Detected in many" "liver cancer: 127.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 31.5;Hep G2: 47.8;T-47d: 22.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006804 Approved NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA006804: AB_1079046" "unprognostic (6.74e-3)" "unprognostic (6.00e-2)" "unprognostic (4.10e-2)" "unprognostic (1.16e-1)" "unprognostic (2.72e-1)" "unprognostic (9.96e-2)" "unprognostic (4.22e-3)" "unprognostic (1.27e-1)" "unprognostic (4.13e-3)" "unprognostic (9.54e-2)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" "prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (7.96e-2)" 1.8 0.9 5.6 0.2 8.8 0.0 11.6 7.0 7.2 1.6 4.2 1.1 1.4 4.0 3.9 0.3 7.4 4.0 5.1 5.7 6.5 200.5 866.2 11.8 0.4 7.5 8.1 1.3 272.1 24.2 14.8 0.5 7.5 20.1 0.3 0.3 15.6 4.7 22.1 0.9 1.1 0.2 6.5 2.6 58.2 1.3 7.6 0.2 19.9 5.4 0.1 0.6 0.4 11.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.5 0.0 0.1 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.8 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.3 0.1 0.0 0.0 3.2 0.2 0.1 0.0 0.2 0.5 22.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.8 7.0 7.2 5.7 6.5 7.5 8.1 7.5 6.5 7.6 11.7 0.5 9.6 32.4 8.8 3.0 0.1 5.1 0.0 0.0 7.2 12.0 8.9 3.4 51.5 1.3 33.1 0.0 0.1 0.0 0.1 52.8 7.5 8.9 4.9 1.0 1.1 2.4 10.7 2.3 26.5 0.3 1.9 18.3 12.5 2.5 0.1 8.6 442.2 1.1 0.0 1.7 2.4 0.0 9.7 0.3 26.0 0.0 1.8 0.0 2.8 0.6 1.6 0.0 0.0 41.6 14.4 0.0 0.4 0.0 7.5 0.0 201.0 0.0 0.6 0.0 0.2 0.2 0.0 0.4 0.0 0.0 0.8 1.8 0.1 0.1 0.5 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 908 "liver: 5440.6" "Cell type enriched" "Detected in some" 38 "Hepatocytes: 6095.8" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "Hep G2: 21.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" NA NA 425000000000 190000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" 1.1 0.8 0.8 0.1 0.7 0.1 5.9 1.0 1.0 1.6 0.6 1.2 0.4 1.0 0.2 0.5 1.6 0.3 0.9 0.7 0.7 1.4 5440.6 1.2 0.3 0.7 0.7 1.6 5.5 0.1 1.2 0.3 0.7 2.4 0.6 1.7 1.1 0.6 0.3 1.6 1.1 0.3 0.6 3.8 0.9 1.1 0.8 0.1 0.9 0.0 0.1 1.1 1.2 0.7 0.2 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.3 1.3 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.6 0.2 21.3 0.0 3.0 0.0 0.8 0.6 0.1 0.0 0.5 0.1 0.2 0.4 0.1 0.1 0.4 0.0 0.0 0.3 0.9 0.0 0.1 1.3 0.2 0.0 0.1 0.2 0.0 1.0 3.0 0.2 0.2 1.1 0.0 0.5 0.3 0.2 1.0 0.1 0.4 0.2 0.9 0.2 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 1.0 1.0 0.7 0.7 0.7 0.7 0.7 0.6 0.8 0.7 0.5 3.2 0.5 0.3 15.1 0.6 0.2 0.2 0.0 1.5 19.1 7.7 0.7 80.1 0.2 0.0 2.1 0.1 0.1 0.6 0.0 0.1 2.3 0.2 0.3 6.2 0.0 157.7 0.7 0.6 0.1 0.4 0.0 1.2 0.0 1.1 132.8 6095.8 0.2 0.0 0.8 0.7 0.0 155.3 0.2 2.9 0.3 0.2 0.0 1.0 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.7 0.2 0.0 1.0 2.1 0.0 0.4 0.5 0.6 0.5 0.0 0.3 0.0 11.3 0.2 0.5 0.3 HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Cell line enhanced" "Detected in many" "HHSteC: 162.8;SK-MEL-30: 100.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" 9.6 17.4 18.4 2.9 17.8 2.9 9.6 19.9 26.4 10.0 23.4 16.0 6.7 7.6 11.1 17.4 8.7 5.7 6.7 17.2 18.1 18.6 29.7 10.7 4.2 19.1 18.5 6.6 20.4 19.7 6.7 9.9 19.6 10.2 13.1 14.8 12.8 7.6 12.5 16.0 6.5 5.7 18.1 5.2 10.1 0.8 20.3 4.3 8.9 10.6 4.9 6.2 10.6 17.2 32.2 8.6 0.3 0.5 4.6 15.4 12.7 14.3 32.2 14.8 13.0 16.5 21.7 0.0 3.6 18.8 0.2 18.3 28.5 18.9 7.0 30.6 6.7 0.0 8.8 9.6 162.8 0.0 0.0 18.0 49.6 1.7 10.8 31.5 0.3 4.8 0.0 0.0 0.7 26.8 0.1 0.0 0.0 17.6 30.1 0.3 0.0 0.0 53.7 7.6 0.5 1.8 15.2 20.9 100.2 1.4 11.9 7.6 0.0 0.1 0.0 0.4 0.1 0.0 16.7 0.0 0.2 8.9 0.6 31.9 6.8 8.6 5.8 4.4 6.9 2.2 10.1 6.2 2.8 2.5 26.0 14.0 0.4 5.2 1.6 3.3 4.9 6.2 18.4 17.8 19.9 26.4 17.2 18.1 19.1 18.5 19.6 18.1 20.3 17.2 36.4 54.5 34.5 12.1 5.0 39.8 66.0 135.5 67.2 12.0 89.8 93.6 12.4 48.6 109.2 49.7 22.9 126.6 9.6 119.8 68.4 63.8 1.3 47.2 13.2 23.0 11.5 11.4 5.7 62.1 67.1 16.0 31.6 59.4 19.0 37.2 30.0 122.5 44.7 20.2 11.0 81.3 71.2 20.5 18.0 1.3 19.9 16.0 39.2 6.5 4.0 33.2 6.2 1.0 3.1 137.3 99.6 24.5 2.3 80.2 70.6 80.6 80.3 33.0 0.0 6.3 15.9 1.3 1.3 46.8 57.8 117.4 12.2 34.5 99.6 104.4 HSPA4L "APG-1, HSPH3, Osp94" ENSG00000164070 "Heat shock protein family A (Hsp70) member 4 like" O95757 4 127781821-127840733 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.7" "Cell type enhanced" "Detected in many" "Early spermatids: 436.6;Late spermatids: 901.8;Spermatocytes: 203.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "HAP1: 82.3" "Low region specificity" "Detected in all" "CAB034450, HPA039149, HPA061446" Enhanced Approved Centrosome,Cytosol NA NA 1000000 "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Centrosome, Cytosol" "CAB034450: AB_2119823, HPA039149: AB_2676366, HPA061446: AB_2684520" "unprognostic (6.66e-2)" "unprognostic (2.39e-1)" "unprognostic (5.33e-2)" "unprognostic (9.40e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (1.23e-3)" "unprognostic (2.41e-1)" "unprognostic (3.90e-1)" "unprognostic (2.38e-4)" "unprognostic (1.40e-2)" "unprognostic (3.28e-1)" "prognostic favorable (3.80e-9)" "unprognostic (8.53e-2)" "unprognostic (1.56e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (6.78e-4)" 1.3 11.3 12.0 1.0 10.5 3.0 3.5 21.7 30.6 3.5 13.5 2.6 2.3 1.0 1.2 13.7 7.0 3.7 6.4 10.6 32.7 13.3 7.4 1.5 0.3 15.2 17.7 3.8 4.0 11.1 8.0 2.9 21.5 4.1 3.5 26.9 5.7 4.9 1.5 8.4 1.2 3.0 12.9 0.9 2.1 108.7 17.7 4.0 3.9 3.6 4.7 2.8 7.7 15.9 20.6 26.5 14.0 22.1 9.5 9.5 16.2 9.1 3.7 8.6 9.5 19.7 9.2 0.1 16.4 2.6 7.0 4.7 82.3 32.9 11.7 38.7 24.7 11.0 33.5 23.7 3.5 42.3 17.9 8.7 29.7 5.7 20.3 8.9 11.3 9.4 19.8 12.2 10.9 14.9 13.6 3.7 3.3 21.5 21.6 0.1 1.5 2.0 29.1 9.2 25.7 9.4 16.4 28.2 1.5 8.3 21.7 7.1 3.2 3.0 0.1 3.7 22.1 23.6 29.3 6.4 11.7 28.3 9.4 0.6 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.0 10.5 21.7 30.6 10.6 32.7 15.2 17.7 21.5 12.9 17.7 15.9 2.7 3.2 9.3 17.6 1.1 28.4 91.9 31.3 40.9 57.7 7.7 9.4 18.1 12.8 27.6 9.2 104.3 10.0 0.8 3.4 19.6 6.8 436.6 17.8 1.6 6.8 18.4 0.0 47.1 2.9 2.1 8.1 2.6 5.2 15.8 2.5 1.8 9.7 1.2 40.4 70.4 3.5 24.4 2.5 9.7 901.8 10.2 4.7 8.8 7.5 3.0 16.6 2.1 19.6 9.3 2.8 0.3 9.8 0.4 26.2 0.3 24.6 52.0 66.8 0.0 18.7 12.5 203.1 13.5 47.5 42.5 16.7 4.2 2.8 5.3 65.2 HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2969.8;tongue: 1759.1" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 165.7;Fibroblasts: 125.2;Leydig cells: 271.8;Peritubular cells: 220.4;Smooth muscle cells: 102.6;Theca cells: 311.0" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1774.3;ASC TERT1: 742.0;HHSteC: 599.9;HSkMC: 700.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nucleoli,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 310000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Nucleoli, Golgi apparatus" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" 650.0 414.0 37.3 45.4 40.6 0.4 394.9 32.5 49.2 581.9 26.1 699.9 28.1 565.1 101.6 112.3 495.1 97.9 1463.9 30.0 43.6 69.0 42.3 126.6 5.7 76.7 48.5 455.2 50.5 4.2 17.5 40.2 73.7 271.2 44.0 21.1 115.9 194.7 2969.8 39.1 180.0 278.2 50.8 15.7 362.1 60.6 53.8 6.2 99.5 1759.1 2.7 537.3 290.6 49.3 0.6 0.7 2.1 2.5 1774.3 742.0 1.2 83.0 1.3 4.9 9.3 1.1 0.4 0.7 0.6 252.4 0.0 0.2 0.4 0.7 3.9 0.9 0.5 0.4 1.3 0.5 599.9 0.2 0.9 700.3 0.0 19.1 0.9 2.2 5.4 0.3 0.5 1.0 0.2 0.3 0.4 1.9 1.2 2.3 0.6 1.5 0.5 0.7 0.0 0.1 0.8 0.7 0.1 0.2 0.7 0.3 0.3 0.5 0.1 153.2 0.9 17.3 0.6 1.0 2.8 0.3 20.5 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.3 40.6 32.5 49.2 30.0 43.6 76.7 48.5 73.7 50.8 53.8 49.3 11.1 3.2 0.6 1.6 0.1 1.8 0.4 0.0 3.4 7.8 0.5 0.5 29.7 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 0.1 27.0 4.9 165.7 3.6 0.0 5.2 0.2 0.0 2.5 125.2 4.1 3.5 0.0 3.6 17.5 0.3 5.0 0.0 0.5 0.0 0.0 0.3 3.6 18.9 271.8 2.7 1.8 0.0 0.6 44.5 0.0 0.0 0.1 0.2 0.0 220.4 0.1 0.4 0.0 0.4 0.0 2.8 26.3 38.0 102.6 2.3 1.4 1.9 2.0 4.8 1.8 311.0 0.0 0.5 IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 433.4;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040523: AB_2677021, HPA076040: " "unprognostic (1.51e-2)" "unprognostic (1.19e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (9.35e-2)" "unprognostic (2.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.28e-2)" "unprognostic (2.98e-2)" "unprognostic (5.40e-2)" "unprognostic (7.39e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (3.91e-2)" 40.7 47.5 27.5 16.9 28.2 27.3 34.1 32.6 37.3 33.3 32.6 41.2 20.0 30.4 31.4 26.6 28.2 23.0 56.9 27.4 29.6 39.4 46.0 31.3 27.0 27.6 27.8 35.6 23.3 45.6 31.1 24.2 28.6 26.6 29.1 22.3 22.4 29.3 43.0 22.6 26.2 27.4 27.5 25.9 29.9 65.8 29.0 28.5 28.8 72.6 31.0 30.6 29.9 31.8 41.0 40.8 4.7 0.5 73.4 140.7 0.9 33.4 76.8 48.7 46.4 0.5 44.2 21.1 17.6 106.7 35.2 27.8 15.4 32.2 48.5 81.2 26.8 26.7 16.1 27.5 139.6 0.1 21.2 85.1 92.9 36.6 42.6 93.6 49.2 37.8 0.4 13.3 100.1 39.4 106.6 4.2 6.4 53.6 20.6 26.0 0.1 6.1 79.4 21.1 29.0 56.2 26.0 37.2 52.6 2.4 37.9 46.4 38.6 38.7 17.0 17.5 52.6 10.6 0.7 8.2 53.4 16.6 44.3 33.3 38.0 31.9 30.2 35.3 33.8 38.5 35.2 34.6 49.6 32.7 27.2 30.9 23.0 37.6 42.8 52.4 46.0 25.6 27.5 28.2 32.6 37.3 27.4 29.6 27.6 27.8 28.6 27.5 29.0 31.8 44.4 32.1 26.2 25.1 53.7 89.9 100.5 92.4 21.6 33.6 41.3 51.2 45.4 52.9 40.1 49.7 12.5 74.2 65.0 36.2 92.0 68.9 433.4 49.9 56.9 30.1 25.7 41.4 43.2 76.9 109.8 73.5 16.8 50.1 36.8 74.0 36.4 53.1 87.4 42.1 35.1 28.6 42.7 78.2 95.2 503.0 93.8 66.3 92.5 19.7 116.8 44.0 80.3 23.1 44.4 90.5 37.3 73.0 38.5 75.6 68.0 138.8 42.7 57.4 98.6 82.8 75.2 243.2 48.8 41.4 95.8 44.5 64.9 87.0 47.5 89.5 IDH2 ENSG00000182054 "Isocitrate dehydrogenase (NADP(+)) 2" P48735 15 90083045-90102477 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 492.6;skeletal muscle: 1302.3;tongue: 1611.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 732.5;Distal tubular cells: 1168.0;Extravillous trophoblasts: 586.7;Syncytiotrophoblasts: 573.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 425.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007831 Enhanced Supported Mitochondria NA NA 5200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA007831: AB_1851397" "unprognostic (2.45e-2)" "prognostic favorable (5.15e-5)" "unprognostic (2.92e-1)" "unprognostic (1.53e-1)" "unprognostic (3.53e-1)" "unprognostic (8.46e-2)" "unprognostic (3.83e-2)" "unprognostic (2.55e-3)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.76e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-3)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-2)" 32.8 10.5 56.5 60.2 67.8 161.1 51.1 57.1 59.8 36.6 76.6 95.9 97.2 29.0 12.5 140.6 32.7 31.7 492.6 47.2 55.0 208.3 274.7 32.0 77.1 61.0 61.3 13.6 128.7 104.0 15.5 87.3 54.4 76.2 84.1 5.4 163.1 90.4 1302.3 61.8 84.3 79.8 52.9 36.8 175.7 5.3 71.6 148.7 16.0 1611.3 66.0 53.3 49.4 57.6 61.3 33.5 169.9 169.8 23.3 28.3 144.5 74.5 110.8 68.0 72.6 16.1 51.1 72.7 21.0 61.2 65.1 20.8 25.1 22.4 32.0 143.8 16.9 122.9 12.7 119.7 28.1 85.1 118.2 59.7 12.7 16.3 13.0 82.1 141.0 246.4 18.9 59.3 53.0 175.3 425.0 131.2 51.8 81.9 14.3 352.0 122.4 213.7 105.6 71.3 244.5 125.3 92.1 359.8 29.9 94.2 290.9 256.9 34.0 120.4 17.0 16.1 34.9 101.5 20.5 9.0 38.4 175.0 71.2 45.0 112.8 75.6 105.9 199.1 53.2 70.1 77.0 120.1 136.9 47.7 42.9 71.8 22.9 99.9 252.1 79.4 72.4 163.4 56.5 67.8 57.1 59.8 47.2 55.0 61.0 61.3 54.4 52.9 71.6 57.6 16.9 6.4 21.0 40.1 64.2 39.9 98.8 91.6 12.5 6.2 90.5 48.1 445.9 114.4 95.8 75.4 10.4 732.5 84.0 70.0 1168.0 252.8 5.6 96.4 25.7 41.6 61.7 193.8 11.8 288.8 586.7 44.7 88.2 50.9 31.6 29.2 38.2 283.1 263.7 10.1 8.3 158.3 229.9 77.7 101.1 3.2 14.0 79.0 58.7 5.6 85.3 20.9 119.4 16.6 27.3 116.6 105.0 35.3 185.9 170.3 69.6 205.0 167.9 5.4 13.1 60.8 73.4 0.6 15.6 113.3 67.1 573.0 88.1 14.7 305.1 140.1 IFFO1 "HOM-TES-103, IFFO" ENSG00000010295 "Intermediate filament family orphan 1" Q0D2I5 12 6538961-6556073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Sertoli cells: 32.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069344 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "HPA069344: AB_2686126" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (4.38e-2)" "unprognostic (3.33e-3)" "unprognostic (2.69e-2)" "unprognostic (1.43e-3)" "unprognostic (4.37e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (5.25e-2)" "prognostic favorable (6.53e-5)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.47e-7)" "unprognostic (5.71e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (5.58e-2)" 9.4 7.7 5.4 5.7 5.8 6.3 6.0 6.1 11.5 10.8 3.0 9.1 3.0 10.3 1.5 2.5 8.2 4.4 8.2 6.1 6.3 4.7 5.6 8.0 7.3 6.9 5.1 7.9 3.2 0.6 7.4 4.9 7.2 5.6 2.5 3.6 3.0 5.0 10.6 3.4 6.2 5.3 4.7 11.5 3.7 7.2 6.5 5.0 4.0 4.6 4.8 8.8 6.8 7.6 0.1 0.0 6.1 0.0 9.1 15.0 0.0 9.2 8.3 7.3 6.4 1.2 0.1 1.7 0.0 8.9 2.3 0.0 4.6 1.3 2.4 13.8 15.2 7.2 0.2 10.2 6.3 7.3 11.5 9.2 0.0 5.5 0.0 8.6 7.2 7.7 0.0 2.0 18.2 0.0 6.5 5.8 14.1 0.0 0.0 9.7 10.6 3.3 2.4 0.0 0.0 5.5 0.0 0.0 4.6 6.2 0.0 7.1 11.1 7.0 0.0 5.7 5.2 3.0 0.8 5.6 5.2 3.1 18.7 0.1 4.8 2.8 1.6 3.3 1.5 0.8 1.4 1.7 3.1 0.9 0.5 0.9 1.3 2.7 6.6 1.6 1.1 2.4 5.4 5.8 6.1 11.5 6.1 6.3 6.9 5.1 7.2 4.7 6.5 7.6 14.9 0.0 2.4 16.0 8.9 2.5 0.3 0.7 0.0 15.0 1.3 2.7 10.9 1.5 0.7 0.0 4.2 4.4 17.7 0.6 1.9 0.7 13.2 0.5 9.2 12.6 0.0 3.8 28.9 1.4 3.1 14.1 1.5 0.6 1.3 11.6 11.7 6.5 21.6 21.9 20.5 1.4 0.0 23.1 9.1 11.2 19.0 17.4 19.6 15.9 12.7 11.1 16.5 13.0 10.5 0.4 1.4 13.5 12.0 0.3 1.2 2.8 0.2 12.7 32.9 15.8 13.2 5.6 5.0 0.6 2.0 1.2 12.9 10.1 1.1 0.2 IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.5;lymphoid tissue: 7.4" "Group enriched" "Detected in many" 12 "dendritic cells: 283.2;T-cells: 200.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" NA NA 1470 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 7: Non-specific - Mitochondria" "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" 0.7 0.7 0.1 3.5 0.2 11.5 0.3 0.0 0.1 0.1 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.5 0.2 0.0 0.0 0.3 1.5 1.8 7.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.9 0.2 0.0 0.0 0.3 0.2 0.0 1.3 0.4 0.1 0.1 0.5 0.3 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.4 6.6 0.0 0.4 0.5 3.7 0.1 0.9 0.0 0.0 0.1 0.9 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.0 0.0 0.0 3.1 3.2 1.3 0.0 0.0 0.0 4.8 5.5 0.2 1.5 0.0 0.0 0.0 0.0 283.2 0.1 0.0 0.0 0.2 1.0 1.1 1.3 0.0 0.4 0.0 0.0 0.0 1.5 6.1 1.1 0.0 0.0 1.4 1.2 0.1 0.0 0.0 0.5 0.0 4.4 5.5 0.0 0.0 10.4 7.2 0.0 0.0 0.0 19.6 0.0 0.1 0.0 1.1 0.0 10.9 0.2 0.0 0.3 0.0 0.0 0.0 1.0 2.9 0.0 0.0 0.8 4.0 0.0 200.1 0.0 0.2 0.2 IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 86.7;cervix: 89.0" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 1279.3;Leydig cells: 1103.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Cell line enhanced" "Detected in some" "ASC diff: 37.9;HDLM-2: 49.6;K-562: 22.4;Karpas-707: 11.3;U-266/70: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048946 Approved "Secreted to blood" NA NA 103000000 330000000 "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" 86.7 5.1 1.2 27.1 1.8 0.9 38.7 0.3 2.3 89.0 1.3 6.9 5.4 46.9 10.6 6.6 13.0 21.5 15.1 2.2 1.0 3.1 83.5 11.6 6.5 2.5 1.1 9.0 3.9 1.4 1.2 24.2 2.0 38.5 6.7 5.4 7.6 33.4 8.5 4.9 5.7 74.3 1.2 9.8 7.7 7.6 2.0 3.1 25.4 5.9 3.7 21.3 22.7 0.9 0.3 0.0 0.0 0.0 37.9 0.0 0.2 0.3 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 49.6 0.0 0.1 0.7 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 22.4 11.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.2 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.4 1.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.8 0.3 2.3 2.2 1.0 2.5 1.1 2.0 1.2 2.0 0.9 11.8 3.2 2.2 1.0 8.5 2.5 0.7 0.0 1.8 168.1 4.0 6.2 0.4 2.8 0.7 0.0 0.0 1.1 0.6 0.2 0.0 0.0 17.5 35.8 1279.3 38.9 0.0 5.3 1.2 0.6 1.5 259.7 2.6 34.5 0.0 0.3 6.4 243.0 122.0 0.0 123.9 0.0 16.2 25.8 12.5 58.0 1103.2 42.0 14.2 27.2 3.6 4.4 0.0 0.5 0.9 0.1 0.0 193.4 66.9 1.2 0.0 1.4 0.1 9.0 0.0 139.3 19.6 1.9 1.2 1.6 2.7 1.2 9.1 69.4 0.2 0.4 IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1198.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 994.8" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Hep G2: 54.7;U-2197: 84.9;U-87 MG: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 28100000 25000000 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" 2.6 0.1 0.2 0.0 0.2 0.0 2.4 0.2 0.3 0.3 0.1 0.0 0.3 79.6 0.1 0.0 4.1 0.3 0.5 0.2 0.3 1.6 1198.4 0.1 0.1 0.8 0.3 46.3 0.5 0.0 0.5 204.5 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.3 1.1 0.3 0.0 0.0 0.0 0.2 0.2 0.2 6.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.6 0.3 1.4 0.1 1.6 0.3 0.0 0.0 0.7 0.0 0.0 0.3 0.5 54.7 0.3 1.1 0.1 0.1 0.7 11.3 0.1 0.6 0.3 0.0 0.2 0.1 1.3 0.0 0.0 0.2 0.0 0.0 2.8 0.0 0.3 0.0 2.2 0.0 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 84.9 0.0 0.0 0.0 0.2 145.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.2 0.3 0.8 0.3 0.9 0.2 0.3 0.2 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 5.7 1.0 35.8 0.7 0.0 0.0 0.9 0.0 0.0 0.0 11.0 0.1 4.7 94.3 0.9 3.5 10.7 0.1 0.0 1.6 1.8 0.0 15.9 0.0 2.1 6.8 994.8 1.7 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.1 0.5 0.0 0.0 3.4 0.8 0.0 0.0 0.0 IGHD "FLJ00382, FLJ46727, MGC29633" ENSG00000211898 "Immunoglobulin heavy constant delta" P01880 14 105836765-105845678 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 330.9" "Group enriched" "Detected in some" 47 "B-cells: 261.8;Plasma cells: 588.1;T-cells: 474.2" "Cancer enhanced" "Detected in many" "lung cancer: 58.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 63 "memory B-cell: 279.1;naive B-cell: 815.9" "Lineage enriched" "Detected in many" 93 "B-cells: 815.9" "Group enriched" "Detected in some" 7 "Daudi: 82.3;U-698: 95.8" CAB012703 Approved "Immunoglobulin genes" NA NA 14000000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB012703: AB_10554307" "prognostic favorable (1.49e-6)" "unprognostic (1.84e-2)" "unprognostic (3.99e-2)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (2.08e-3)" "unprognostic (4.63e-2)" "unprognostic (3.28e-1)" "unprognostic (8.18e-2)" "unprognostic (6.16e-2)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-3)" "unprognostic (5.76e-2)" "unprognostic (2.64e-1)" "unprognostic (3.82e-3)" "unprognostic (4.30e-2)" 2.8 0.4 0.0 35.4 0.0 39.2 9.3 0.0 0.4 0.9 0.0 2.2 3.4 5.0 0.2 2.8 0.6 19.0 5.7 0.0 0.0 2.1 3.5 34.1 111.6 0.2 0.0 0.3 0.4 0.2 0.0 0.3 0.0 6.4 1.9 0.0 67.1 1.2 0.4 1.5 17.6 0.9 0.0 146.7 43.3 0.3 0.1 8.3 1.3 0.0 330.9 20.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 12.4 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 95.8 0.0 0.0 0.0 2.7 0.5 0.3 0.4 0.3 0.2 279.1 0.3 0.8 0.7 815.9 1.0 0.3 3.3 0.3 0.5 8.7 0.4 39.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 261.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.6 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 9.2 0.0 0.0 0.0 0.0 0.0 588.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 474.2 0.0 0.0 0.0 IGHD3-16 IGHD316 ENSG00000211917 "Immunoglobulin heavy diversity 3-16" 14 105895634-105895670 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "bone marrow: 4.0;intestine: 2.6;lymphoid tissue: 4.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 27.0" "Lineage enriched" "Detected in many" 12 "B-cells: 27.0" "Group enriched" "Detected in some" 16 "HEL: 2.4;HMC-1: 1.3;NB-4: 1.0" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" 0.0 0.0 0.0 1.7 0.0 4.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.8 0.0 0.0 0.0 2.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 27.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHD3-9 "DXP1, IGHD39" ENSG00000211924 "Immunoglobulin heavy diversity 3-9" 14 105904681-105904711 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11.9;stomach 1: 4.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 214 "memory B-cell: 8.9;naive B-cell: 33.8" "Lineage enriched" "Detected in single" 339 "B-cells: 33.8" "Cell line enriched" "Detected in some" 5 "HEL: 5.5" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "unprognostic (1.74e-1)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.0 0.1 0.0 0.0 2.1 1.6 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.9 0.4 0.0 0.0 2.0 0.0 0.1 2.8 4.8 0.0 0.1 2.2 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2478.2" "Group enriched" "Detected in some" 10 "B-cells: 964.5;Plasma cells: 2099.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 122.7;naive B-cell: 73.7" "Lineage enriched" "Detected in single" 571 "B-cells: 122.7" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 339.7" HPA001245 Approved "Immunoglobulin genes" NA NA 170000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" 80.0 2.1 0.4 2478.2 0.6 42.2 5.8 0.5 1.0 33.9 0.3 40.6 85.5 10.8 0.2 401.2 28.5 101.3 19.2 0.3 0.4 44.0 43.7 49.4 136.5 0.6 0.4 3.9 4.2 0.5 1.9 0.2 1.3 31.2 44.3 0.1 16.4 4.1 0.8 4.7 186.2 1.8 1.1 831.6 57.4 2.2 0.4 49.9 108.3 0.0 872.5 588.7 29.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.7 0.0 0.5 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 43.2 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.3 0.6 339.7 0.0 0.0 3.5 3.7 0.3 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.3 1.5 0.6 0.1 57.5 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 122.7 0.0 0.0 0.1 73.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 19.6 0.4 0.6 0.5 1.0 0.3 0.4 0.6 0.4 1.3 1.1 0.4 0.3 1.3 6.4 118.8 0.0 964.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.0 8.6 3.7 0.0 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.0 0.4 2.5 27.8 26.7 0.0 0.0 0.0 4.3 0.0 0.0 50.4 0.0 16.4 36.7 0.0 0.0 0.0 10.5 0.0 51.9 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.3 0.0 2099.3 0.2 0.0 10.6 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 152.3 0.0 12.8 0.1 IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 316.6;lymphoid tissue: 568.1" "Cell type enriched" "Detected in single" 36 "B-cells: 3.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 74.8;naive B-cell: 66.7" "Lineage enriched" "Detected in many" 16 "B-cells: 74.8" "Group enriched" "Detected in some" 6 "Daudi: 9.4;U-698: 4.8" HPA006014 Approved "Immunoglobulin genes" NA NA 1200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "HPA006014: " 4.5 28.4 0.0 229.8 0.0 38.7 102.0 0.0 0.9 68.9 0.1 274.0 0.9 10.8 0.0 111.5 20.0 92.5 6.2 0.0 0.0 5.5 7.3 128.3 121.2 0.1 0.0 54.0 5.7 0.4 0.3 0.2 0.2 6.9 316.6 0.0 75.5 19.0 0.1 1.6 51.6 10.9 0.0 203.8 148.3 0.1 0.0 39.3 7.3 0.0 568.1 196.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.4 0.0 4.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 0.0 0.0 0.0 66.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.4;lymphoid tissue: 133.9" "Cell type enriched" "Detected in some" 4 "Plasma cells: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 109 "memory B-cell: 8.3;naive B-cell: 13.5" "Lineage enriched" "Detected in single" 136 "B-cells: 13.5" "Cell line enriched" "Detected in some" 5 "Karpas-707: 5.4" "Immunoglobulin genes" NA NA 560000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" 3.9 2.9 0.3 58.3 0.0 39.0 21.1 0.0 0.6 7.7 0.2 60.8 8.3 0.5 0.0 4.7 0.8 3.1 0.8 0.0 0.0 2.1 2.8 49.1 7.5 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.0 2.6 97.4 0.0 42.2 8.7 0.3 0.2 42.9 0.2 0.1 68.5 24.2 0.2 0.0 45.6 5.9 0.0 133.9 10.4 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 73.4;pituitary gland: 167.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 3.9;Bipolar cells: 14.0;Breast glandular cells: 5.0;Horizontal cells: 3.3;Melanocytes: 3.6;Skeletal myocytes: 7.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Hep G2: 47.6;SH-SY5Y: 31.2" "Region enhanced" "Detected in all" "hypothalamus: 144.0" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" NA NA 100000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" 1.9 12.5 9.7 0.8 10.0 0.1 2.8 9.7 9.7 3.3 4.8 0.9 0.4 1.2 2.4 1.6 2.5 1.2 12.1 7.5 73.4 0.7 1.5 0.3 0.4 10.0 21.6 1.1 2.6 0.8 167.8 0.7 24.0 4.0 0.4 6.4 2.4 5.7 2.0 1.4 0.6 3.1 7.4 0.3 1.0 12.2 32.4 0.6 4.5 5.1 0.9 0.4 0.9 8.4 0.4 0.6 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 6.0 0.0 0.0 0.1 1.8 0.0 0.0 6.0 0.4 0.0 3.0 47.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 4.1 2.8 0.0 0.0 0.0 0.1 0.1 0.2 3.4 31.2 0.0 0.2 0.0 4.1 0.6 0.0 0.0 0.5 0.8 0.0 4.1 1.2 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.0 9.7 9.7 7.5 73.4 10.0 21.6 24.0 7.4 32.4 8.4 0.2 3.2 0.6 3.9 0.2 0.0 0.5 0.0 1.2 14.0 5.0 1.7 2.3 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.3 1.5 0.0 0.1 0.0 0.7 0.7 0.3 0.0 3.3 0.4 0.0 0.0 0.0 0.8 1.1 0.0 0.2 3.6 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.7 0.0 7.2 0.3 0.1 0.4 0.0 0.4 0.3 0.1 0.0 0.0 0.3 IHO1 "CCDC36, CT74, FLJ25320, LELA1" ENSG00000173421 "Interactor of HORMAD1 1" Q8IYA8 3 49198428-49258106 "Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 7.5;testis: 26.5" "Cell type enhanced" "Detected in some" "Adipocytes: 1.7;Cardiomyocytes: 1.4;Fibroblasts: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 2.9;hTEC/SVTERT24-B: 9.2;LHCN-M2: 4.0;NTERA-2: 2.5;U-2197: 5.1;WM-115: 2.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA045690, HPA069534" Approved Approved Nucleoplasm NA NA "Cluster 17: Basophils - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA045690: AB_10964634, HPA069534: AB_2686146" "unprognostic (1.54e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-1)" "unprognostic (5.05e-2)" "unprognostic (3.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.36e-2)" "unprognostic (1.49e-2)" "unprognostic (9.94e-3)" "unprognostic (2.62e-1)" "unprognostic (1.38e-1)" "unprognostic (1.36e-2)" "unprognostic (5.51e-4)" "unprognostic (3.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.59e-2)" "unprognostic (6.33e-2)" 3.2 1.4 0.2 0.3 0.2 0.2 1.8 0.9 0.5 1.3 7.5 1.1 0.2 1.2 0.4 0.4 1.3 0.7 1.1 0.4 0.0 0.3 0.1 0.5 0.3 0.1 0.3 3.8 0.2 0.1 0.2 0.9 0.1 0.4 0.1 0.7 0.3 0.5 0.9 0.6 0.4 1.0 0.1 0.5 0.3 26.5 0.5 0.1 1.0 0.8 0.1 0.8 0.6 0.1 0.0 0.1 0.0 0.0 1.9 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.1 1.7 0.0 9.2 0.0 0.0 1.2 0.0 0.0 0.1 4.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.5 0.4 0.0 0.1 0.3 0.1 0.1 0.5 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL1RAPL2 "IL-1R9, IL1R9, IL1RAPL-2, TIGIRR-1" ENSG00000189108 "Interleukin 1 receptor accessory protein like 2" Q9NP60 X 104566199-105767829 "Enzymes, Predicted membrane proteins" "Hydrolase, Receptor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;parathyroid gland: 1.0" "Group enriched" "Detected in some" 22 "Excitatory neurons: 191.3;Inhibitory neurons: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.4;hTERT-HME1: 5.6;NTERA-2: 1.0;RT4: 2.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.62e-1)" "unprognostic (1.50e-1)" "unprognostic (1.66e-2)" "unprognostic (3.09e-1)" "unprognostic (1.48e-4)" "unprognostic (9.32e-3)" "unprognostic (1.67e-1)" "unprognostic (6.80e-5)" "unprognostic (1.78e-2)" "unprognostic (2.79e-3)" "unprognostic (5.91e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.84e-2)" 0.0 1.4 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.9 0.0 0.0 0.0 0.4 0.2 0.0 1.0 0.0 0.4 0.1 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.4 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 2.4 0.1 0.2 0.1 0.0 0.0 191.3 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 117.4 0.0 0.0 0.0 0.0 0.2 5.9 0.0 0.0 2.8 0.0 0.0 0.0 3.0 4.6 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 2.6 0.0 1.4 0.0 0.4 IL23R IL-23R ENSG00000162594 "Interleukin 23 receptor" Q5VWK5 1 67138907-67259979 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.6;testis: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 11.1;Enteroendocrine cells: 3.0;Late spermatids: 6.0;T-cells: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 21.7" "Lineage enriched" "Detected in single" 29 "T-cells: 21.7" "Cell line enhanced" "Detected in some" "HL-60: 2.4;HMC-1: 9.1;K-562: 3.6;U-2197: 13.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056427 Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA056427: AB_2683129" "unprognostic (4.01e-3)" "unprognostic (8.04e-2)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.96e-1)" "unprognostic (3.16e-3)" "unprognostic (1.57e-1)" "unprognostic (2.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.88e-1)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (8.64e-5)" "unprognostic (1.43e-1)" "unprognostic (3.02e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.9 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.4 1.5 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.4 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 13.8 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 21.7 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 11.1 0.2 0.1 0.1 3.0 0.0 0.3 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.2 6.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.1 0.2 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.3 0.0 4.2 0.0 0.4 0.2 IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 18.3;testis: 26.8" "Group enriched" "Detected in many" 5 "Langerhans cells: 295.1;monocytes: 682.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.4" "Group enriched" "Detected in many" 6 "monocytes: 36.8;T-cells: 103.4" "Cell line enhanced" "Detected in many" "EFO-21: 34.3;HDLM-2: 62.4;Karpas-707: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" 1.6 0.6 0.4 18.3 0.6 4.2 0.9 0.8 0.6 1.1 0.7 1.7 4.1 1.6 0.2 0.6 3.9 2.0 0.5 0.6 0.5 4.8 1.2 2.4 9.3 1.7 0.9 0.4 0.7 0.2 0.6 1.9 1.8 0.8 1.4 0.1 0.9 0.5 0.3 1.3 2.7 1.5 1.0 4.1 3.1 26.8 1.2 3.4 0.5 0.2 6.7 4.5 0.5 2.3 1.0 1.2 0.8 0.7 0.0 0.8 0.3 0.5 2.0 1.4 2.1 0.7 1.9 3.5 34.3 0.4 2.9 0.5 0.4 0.0 0.2 62.4 0.2 1.6 0.1 0.5 0.1 1.2 12.3 1.0 0.4 0.6 0.1 0.4 2.6 0.4 0.4 47.3 0.1 0.4 0.7 2.1 0.4 0.9 0.1 1.0 0.9 3.6 2.5 3.2 0.7 0.8 0.5 0.9 0.5 0.2 0.4 2.8 2.9 7.1 1.0 0.1 1.0 4.1 9.7 2.0 1.0 0.5 0.7 0.3 22.0 0.3 6.4 36.8 103.4 0.4 13.2 11.5 11.6 0.2 0.3 0.1 0.5 1.3 5.3 1.3 0.7 8.8 0.4 0.6 0.8 0.6 0.6 0.5 1.7 0.9 1.8 1.0 1.2 2.3 0.8 0.0 0.0 0.0 3.6 9.7 0.6 9.8 0.0 0.1 1.2 1.3 0.5 0.0 5.5 3.7 0.0 0.4 1.0 0.2 0.0 3.5 75.4 2.9 0.6 6.7 0.0 0.0 0.4 4.0 0.7 1.3 0.5 2.1 1.3 0.1 1.1 0.2 97.4 0.0 0.4 0.3 6.1 3.0 295.1 18.4 0.3 38.8 3.6 1.9 682.5 0.1 1.0 0.0 0.4 0.5 0.1 0.4 0.7 1.4 0.3 2.7 1.6 0.2 0.0 0.2 2.5 45.2 3.6 0.4 8.2 0.8 6.3 0.0 0.2 2.1 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INF2 "C14orf151, C14orf173, MGC13251" ENSG00000203485 "Inverted formin 2" Q27J81 14 104681146-104722535 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 229.3;Gastric mucus-secreting cells: 183.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 100.8" "Region enhanced" "Detected in all" "basal ganglia: 224.1" "Low region specificity" "Detected in all" HPA000724 Approved Approved "Nuclear bodies,Endoplasmic reticulum" NA NA 3000000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nuclear bodies" "HPA000724: AB_1078325" "unprognostic (1.42e-1)" "unprognostic (9.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.00e-2)" "unprognostic (1.49e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (8.18e-4)" "unprognostic (1.13e-2)" "unprognostic (9.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-2)" "unprognostic (1.36e-3)" "unprognostic (7.24e-2)" "unprognostic (4.01e-1)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.70e-2)" 42.8 21.4 14.0 8.4 29.6 7.5 35.2 18.3 29.5 28.7 1.4 40.4 21.2 24.3 2.3 20.4 20.9 8.9 24.1 14.7 14.7 27.3 30.2 34.3 6.9 30.7 25.5 13.6 15.7 2.0 8.3 11.7 27.5 23.2 4.7 3.3 17.9 7.5 13.7 26.9 31.7 4.4 12.2 31.4 34.7 32.2 26.3 2.1 20.8 1.5 3.4 30.2 28.5 71.2 26.3 92.1 9.9 16.0 7.6 12.2 84.2 49.0 14.5 21.9 14.0 35.5 40.2 3.7 46.6 17.9 17.0 43.3 9.4 22.7 9.5 18.5 26.6 22.0 59.9 23.9 16.5 6.8 21.0 11.4 14.5 15.8 6.8 15.0 24.1 9.1 10.7 10.5 18.0 30.0 10.2 17.9 17.1 18.3 100.8 29.8 19.2 9.4 12.6 38.0 20.5 12.8 26.4 36.7 11.7 8.0 8.0 4.9 49.9 29.4 22.1 45.7 22.5 6.9 3.7 3.7 41.2 12.1 25.1 0.5 2.1 0.1 0.9 0.7 0.7 1.6 3.2 0.6 2.4 1.5 2.5 1.6 1.6 1.2 0.1 5.1 4.0 3.2 14.0 29.6 18.3 29.5 14.7 14.7 30.7 25.5 27.5 12.2 26.3 71.2 48.8 64.1 13.4 10.1 22.5 22.7 17.5 19.0 17.1 0.3 16.5 14.6 14.3 28.6 15.0 3.7 0.0 54.8 5.2 229.3 5.9 24.1 1.2 7.8 8.6 29.8 17.4 17.2 16.7 25.5 87.8 17.9 183.0 18.2 14.7 8.4 25.4 29.8 32.6 0.0 1.9 86.2 12.2 21.8 35.6 2.1 5.6 25.5 8.8 20.6 14.0 55.3 1.0 11.1 89.6 58.1 110.7 4.5 7.8 26.6 90.4 7.3 9.4 2.0 32.9 5.7 36.1 1.1 4.5 8.5 18.8 31.6 9.3 12.9 66.9 38.2 INSYN2A "C10orf141, FAM196A, FLJ45557, INSYN2" ENSG00000188916 "Inhibitory synaptic factor 2A" Q6ZSG2 10 127135426-127196591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.0" "Cell type enhanced" "Detected in single" "Endothelial cells: 1.4" "Group enriched" "Detected in some" 13 "breast cancer: 3.4;glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "SCLC-21H: 2.7;U-87 MG: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035898, HPA035899" Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" "HPA035898: AB_10964352, HPA035899: AB_10961723" "unprognostic (4.00e-2)" "unprognostic (9.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.66e-3)" "unprognostic (2.18e-1)" "unprognostic (4.70e-2)" "unprognostic (7.30e-2)" "unprognostic (3.62e-1)" "unprognostic (2.18e-2)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (5.47e-2)" "unprognostic (5.07e-2)" "unprognostic (2.86e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" 0.1 0.0 4.5 0.1 6.2 0.0 0.6 2.8 5.8 0.1 1.2 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 3.4 5.3 0.3 0.0 0.2 0.0 4.4 5.4 0.7 0.1 0.0 0.2 0.0 4.2 0.7 0.1 1.6 0.2 0.1 0.0 0.1 0.3 0.1 2.6 0.3 0.2 0.6 8.0 1.1 0.1 0.1 0.1 0.2 0.1 2.3 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 6.2 2.8 5.8 3.4 5.3 4.4 5.4 4.2 2.6 8.0 2.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IQCJ-SCHIP1 ENSG00000283154 "IQCJ-SCHIP1 readthrough" B3KU38 3 158962235-159897366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 7.3;Basal squamous epithelial cells: 12.5;Bipolar cells: 11.5;Excitatory neurons: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA003243, HPA003445" Approved Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA003243: AB_1079877, HPA003445: AB_1079875" 22.0 5.1 82.3 9.7 90.6 2.2 15.4 84.9 165.9 9.2 56.6 49.8 4.5 19.6 6.3 15.4 18.2 12.5 57.2 83.9 73.9 17.8 14.3 19.6 2.2 93.5 88.0 4.4 2.7 1.1 7.3 23.6 92.0 17.7 6.8 14.2 6.5 20.4 27.6 5.7 12.8 25.9 81.5 4.3 18.3 4.7 87.2 2.5 5.7 3.2 1.8 35.8 10.8 110.5 87.9 14.8 28.9 34.4 6.6 6.3 25.1 73.6 17.3 59.4 40.5 55.6 20.9 4.4 46.4 24.6 22.6 34.8 11.3 24.9 48.5 72.7 27.6 0.1 31.2 2.8 7.7 4.2 0.5 6.5 20.8 26.5 31.1 49.3 44.5 4.9 0.0 0.3 27.7 3.9 0.3 0.0 24.2 7.0 31.9 10.2 58.4 0.0 57.6 4.7 5.8 26.8 39.8 16.7 21.8 32.9 9.8 0.8 37.6 34.0 47.5 22.9 101.5 0.3 0.5 0.4 19.1 12.4 92.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 82.3 90.6 84.9 165.9 83.9 73.9 93.5 88.0 92.0 81.5 87.2 110.5 4.7 6.4 0.0 1.0 0.1 1.5 7.3 0.8 12.5 11.5 0.3 0.9 0.6 0.0 1.4 1.8 6.2 0.0 0.1 0.3 0.0 0.9 2.0 2.1 0.8 5.7 0.0 0.0 11.3 0.6 0.0 3.1 0.0 2.3 2.5 0.0 1.8 0.6 0.0 0.0 4.7 0.2 0.0 0.3 1.2 0.6 0.3 1.2 0.0 0.0 0.6 0.5 0.0 0.0 0.6 1.2 0.0 1.2 0.0 1.3 0.0 4.2 2.4 0.6 0.0 2.5 5.4 0.1 0.4 3.5 0.9 0.0 0.5 0.0 0.2 1.6 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRF7 ENSG00000185507 "Interferon regulatory factor 7" Q92985 11 612553-615983 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.2;lymphoid tissue: 33.2" "Cell type enriched" "Detected in many" 7 "dendritic cells: 576.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 12 "plasmacytoid DC: 596.9" "Lineage enriched" "Detected in all" 12 "dendritic cells: 596.9" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 15.5;BJ hTERT+ SV40 Large T+ RasG12V: 9.6;Karpas-707: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017694, HPA052757" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Cytosol "CAB017694: AB_2280489, HPA052757: AB_2681937" "unprognostic (1.39e-2)" "unprognostic (3.26e-2)" "unprognostic (1.08e-3)" "unprognostic (2.45e-1)" "unprognostic (4.52e-2)" "unprognostic (2.73e-1)" "unprognostic (1.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (7.08e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (1.71e-10)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (2.58e-1)" "unprognostic (4.71e-2)" 10.4 2.6 1.3 1.6 1.6 1.6 7.5 1.5 2.1 11.2 2.2 8.8 0.0 3.4 0.0 12.7 4.7 2.2 7.9 1.2 1.6 15.6 38.2 14.4 0.9 2.7 1.6 4.7 5.9 0.2 6.2 0.7 2.4 9.2 0.3 0.3 8.8 0.8 11.3 7.8 15.3 0.9 1.3 33.2 8.6 1.9 1.6 1.4 10.7 1.3 2.2 5.1 7.3 1.6 0.0 0.0 0.7 0.1 0.0 0.6 0.0 0.4 3.9 15.5 9.6 2.2 0.1 0.0 3.7 0.6 3.7 0.5 0.2 0.1 1.0 0.2 0.0 0.1 0.0 0.2 0.8 0.0 0.0 1.6 0.6 0.0 0.6 0.7 0.1 1.9 0.0 6.5 0.1 0.0 0.7 0.0 0.0 3.1 1.3 0.1 0.2 0.0 0.2 0.1 3.1 0.0 0.6 1.8 0.4 0.3 0.0 1.5 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 12.7 20.4 30.6 8.1 46.1 7.8 16.5 6.7 7.0 24.3 20.8 7.5 8.5 12.9 18.7 49.5 596.9 13.5 19.7 1.3 1.6 1.5 2.1 1.2 1.6 2.7 1.6 2.4 1.3 1.6 1.6 65.0 16.0 19.0 2.9 59.2 34.4 32.3 19.6 18.8 0.4 27.7 20.2 4.3 18.6 18.2 20.2 0.0 6.1 576.1 70.1 9.8 29.9 5.9 20.1 6.3 33.0 26.3 4.8 0.0 16.9 39.0 19.3 40.8 21.2 31.7 20.1 17.9 31.7 37.3 0.0 0.1 42.5 22.4 23.2 65.4 28.9 12.2 67.4 37.4 3.7 65.2 2.7 40.2 1.0 1.3 29.9 73.8 4.9 65.1 24.8 37.6 6.3 25.5 4.6 13.1 8.8 19.8 0.4 5.9 8.0 28.4 24.1 42.7 4.6 18.9 34.6 IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899162-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 85.5;lymphoid tissue: 244.1" "Cell type enhanced" "Detected in many" "B-cells: 225.8;dendritic cells: 492.3;Kupffer cells: 105.1;Langerhans cells: 366.0;Macrophages: 122.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2477.4" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2477.4" "Group enriched" "Detected in some" 4 "Daudi: 240.7;THP-1: 382.3;U-698: 928.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "CAB013480: AB_2533439, HPA002267: AB_1079143, HPA002531: AB_1851904" "unprognostic (2.09e-3)" "unprognostic (7.51e-2)" "unprognostic (5.16e-2)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (3.46e-3)" "unprognostic (3.19e-2)" "unprognostic (5.31e-3)" "unprognostic (1.23e-1)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (5.31e-2)" "unprognostic (3.14e-3)" "unprognostic (3.97e-2)" "unprognostic (9.66e-3)" "unprognostic (4.04e-1)" "unprognostic (1.10e-2)" 25.9 7.6 4.7 81.4 5.6 85.5 9.3 7.0 6.2 5.6 5.4 27.1 47.1 8.0 3.1 6.7 6.5 19.7 3.8 6.3 5.4 6.1 36.9 27.4 244.1 9.5 8.5 2.5 3.4 1.7 1.7 10.1 10.0 7.7 33.5 0.8 7.1 8.9 2.0 5.0 56.2 13.5 11.3 137.3 22.9 4.8 12.6 61.5 4.1 1.7 224.9 21.8 1.6 14.0 0.9 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 26.0 0.0 240.7 1.5 0.0 0.0 0.1 1.4 0.0 0.2 0.2 2.7 0.1 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.3 0.5 0.0 0.0 0.6 21.3 0.2 20.6 0.0 7.5 1.1 27.2 0.0 0.0 0.1 0.1 1.0 0.0 0.2 1.4 0.0 382.3 0.6 0.0 10.9 0.2 0.9 0.3 0.3 928.2 0.0 128.4 0.0 9.1 137.1 3.4 3.3 134.3 4.5 347.0 1.8 2.1 291.2 361.3 3.5 2.8 8.4 111.5 97.3 2477.4 0.7 150.1 4.7 5.6 7.0 6.2 6.3 5.4 9.5 8.5 10.0 11.3 12.6 14.0 3.7 0.0 4.2 0.0 225.8 10.5 0.8 0.0 0.6 0.0 2.4 3.4 1.5 2.8 1.3 0.0 0.0 0.8 492.3 13.0 1.9 0.5 1.5 7.3 7.6 7.6 28.7 7.4 0.6 1.4 5.7 10.8 15.3 12.5 2.5 0.4 1.8 6.5 64.1 0.0 0.2 11.8 0.0 105.1 366.0 4.6 0.3 122.2 44.4 33.7 35.3 0.4 23.7 1.0 0.4 0.1 10.7 0.0 14.1 2.3 34.2 3.5 0.0 0.2 6.6 0.7 6.7 0.7 6.7 0.4 9.2 1.1 23.1 48.8 25.6 2.5 IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.8;heart muscle: 9.8;skin 1: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.5;Collecting duct cells: 5.5;Hofbauer cells: 4.7;Late spermatids: 5.1;Melanocytes: 3.6" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HEK 293: 1.9;RPTEC TERT1: 7.1;SK-MEL-30: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Mitochondria" "HPA018332: AB_1851920" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (4.93e-4)" "unprognostic (2.48e-2)" "unprognostic (6.50e-2)" "unprognostic (3.46e-1)" "prognostic favorable (3.34e-4)" "unprognostic (3.63e-2)" "unprognostic (4.36e-2)" "unprognostic (2.93e-2)" "unprognostic (1.50e-2)" "unprognostic (2.83e-2)" "unprognostic (9.63e-3)" "unprognostic (7.12e-3)" "unprognostic (5.48e-2)" "unprognostic (5.23e-3)" 9.8 0.1 0.2 0.0 0.6 0.0 4.8 1.1 0.3 2.3 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.1 9.8 0.0 1.1 2.7 0.0 1.8 0.1 0.5 0.8 0.2 0.1 1.7 0.2 0.1 0.6 0.2 0.0 1.6 1.9 0.0 2.8 8.9 0.3 0.1 0.2 1.3 0.0 0.4 0.6 2.2 0.6 1.3 1.1 0.0 0.5 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.1 0.0 1.1 4.8 0.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.3 0.0 1.1 0.5 0.8 0.6 0.2 0.6 0.2 0.6 0.0 0.0 0.0 0.1 0.8 0.0 0.5 0.0 7.5 0.4 0.6 1.3 0.0 1.2 5.5 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.8 0.0 0.6 0.0 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.7 5.1 0.0 0.1 3.6 0.0 0.6 1.5 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.3 0.1 0.5 0.0 1.0 0.1 0.0 0.0 0.0 0.0 ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA030492: AB_10603772" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.73e-2)" "unprognostic (5.62e-2)" "unprognostic (2.51e-1)" "unprognostic (5.89e-3)" "unprognostic (6.03e-3)" "unprognostic (7.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.21e-1)" "prognostic favorable (1.68e-7)" "unprognostic (3.98e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.98e-5)" "unprognostic (5.23e-2)" 15.1 33.9 20.3 9.7 20.6 15.5 16.9 22.4 23.9 13.7 27.4 16.9 14.2 11.0 46.4 15.4 19.5 7.6 34.3 19.5 21.2 30.6 22.0 12.9 17.0 21.2 21.1 18.1 18.1 12.9 23.4 12.8 21.3 18.5 17.5 19.1 17.8 12.1 38.3 13.3 16.0 8.4 21.1 20.0 18.1 20.6 22.6 18.5 26.0 29.2 17.4 13.7 13.4 21.5 43.4 30.7 28.4 18.1 25.5 37.2 35.9 19.7 26.3 30.2 36.3 36.3 39.3 21.8 25.3 16.6 38.2 30.7 27.8 25.9 40.7 30.7 20.2 13.7 13.1 39.6 38.3 17.7 30.2 31.2 29.0 18.2 20.6 28.0 30.8 44.4 18.2 25.5 32.7 51.0 42.9 34.5 21.0 60.2 28.3 29.8 31.9 21.8 42.6 34.1 19.1 19.6 20.8 24.4 31.8 30.5 60.2 20.9 16.9 17.1 39.5 25.3 17.7 43.3 60.3 40.2 28.0 20.6 25.4 130.8 109.1 159.0 91.8 108.0 93.5 172.3 127.6 111.6 111.0 165.4 148.5 122.1 87.5 101.5 106.6 218.1 157.4 161.3 20.3 20.6 22.4 23.9 19.5 21.2 21.2 21.1 21.3 21.1 22.6 21.5 25.2 19.2 20.4 7.2 36.2 15.4 27.2 74.9 13.6 22.1 36.2 38.2 113.3 22.8 42.7 33.1 12.5 70.8 28.8 45.5 146.8 62.0 41.0 38.3 17.6 27.2 29.3 73.2 4.4 55.0 70.1 28.8 24.5 18.1 12.6 31.8 28.9 42.4 81.5 28.6 5.5 36.3 63.1 33.2 18.3 19.3 33.5 30.4 8.8 2.8 49.0 69.8 41.2 3.0 7.2 59.5 50.8 18.0 25.0 40.2 51.4 133.5 78.6 31.6 13.1 15.1 25.1 107.2 63.7 25.4 13.2 25.4 30.7 43.1 42.3 27.6 ISL2 FLJ10160 ENSG00000159556 "ISL LIM homeobox 2" Q96A47 15 76336773-76342475 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.6;prostate: 2.3;vagina: 3.5" "Cell type enriched" "Detected in some" 7 "Cone photoreceptor cells: 27.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 9.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 15.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "spinal cord: 1.8" HPA075192 Approved "Rods & Rings" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Rods & Rings" "HPA075192: AB_2686738" "unprognostic (7.30e-2)" "unprognostic (7.96e-2)" "unprognostic (9.01e-3)" "unprognostic (4.44e-3)" "unprognostic (1.44e-1)" "unprognostic (7.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.67e-1)" "unprognostic (2.84e-1)" "unprognostic (9.03e-2)" "unprognostic (3.93e-2)" "unprognostic (3.55e-15)" "unprognostic (1.78e-1)" "unprognostic (4.19e-1)" "unprognostic (4.07e-1)" "unprognostic (2.26e-1)" 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.0 1.9 0.8 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.8 0.2 0.0 0.0 0.0 2.6 0.0 0.2 2.3 0.0 1.4 1.8 0.0 0.0 0.6 1.2 0.0 0.0 0.5 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 3.5 0.8 1.5 1.8 0.0 1.7 0.1 0.1 1.5 4.5 2.1 1.2 1.5 3.4 0.7 3.3 2.1 0.0 1.1 1.9 6.4 0.1 0.2 3.2 15.4 1.6 4.0 4.1 1.4 3.6 4.3 0.0 0.8 0.0 0.0 0.0 0.0 4.8 5.1 2.6 0.3 0.1 4.4 8.4 0.0 0.6 2.8 2.7 2.0 4.4 0.0 0.6 4.9 5.0 3.0 0.0 0.0 0.9 0.3 8.2 0.0 1.5 3.2 0.6 4.3 3.8 4.1 2.0 1.1 2.5 0.0 0.0 0.8 0.0 0.1 0.9 0.0 0.8 0.0 0.5 0.1 1.7 0.1 0.0 9.5 0.0 3.5 0.0 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.8 0.2 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.6 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 27.1 0.1 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 3.5 0.6 0.0 0.0 0.0 2.1 0.0 0.2 0.5 1.5 1.0 0.0 0.0 0.3 0.2 0.0 0.0 3.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ISOC2 FLJ23469 ENSG00000063241 "Isochorismatase domain containing 2" Q96AB3 19 55452985-55462343 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 284.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 272.2;Proximal tubular cells: 479.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 270.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043142 Enhanced Approved Mitochondria,Cytosol NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Cytosol "HPA043142: AB_10794653" "unprognostic (2.74e-1)" "unprognostic (8.38e-3)" "unprognostic (7.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-1)" "unprognostic (3.09e-1)" "unprognostic (5.82e-2)" "unprognostic (8.59e-2)" "unprognostic (9.90e-3)" "unprognostic (2.24e-1)" "unprognostic (2.42e-1)" "unprognostic (9.20e-2)" "unprognostic (2.09e-2)" 50.4 55.6 39.7 20.0 41.2 21.4 38.3 42.7 52.4 25.4 48.1 62.1 36.2 28.4 8.1 52.2 25.8 17.2 69.5 39.5 43.9 101.4 284.3 26.4 19.2 46.6 44.4 23.3 44.4 39.9 46.3 9.3 43.7 40.9 16.3 3.3 41.8 28.7 95.7 37.6 37.2 16.8 42.6 50.8 41.4 65.6 42.1 9.9 39.1 49.0 14.0 41.6 30.3 44.4 52.8 78.1 20.1 55.6 13.6 28.4 67.7 37.9 36.7 45.7 46.4 40.0 88.2 98.6 66.2 42.2 44.0 51.1 39.7 46.6 14.6 38.9 270.2 57.6 17.8 128.0 55.6 63.2 163.5 42.5 44.2 29.4 22.0 20.4 42.4 39.3 93.6 61.1 28.9 101.9 0.3 73.6 32.4 113.2 217.9 72.1 44.4 126.0 75.0 47.7 24.7 70.5 35.5 75.3 41.4 11.9 63.8 109.4 32.4 34.0 48.5 38.8 44.7 78.7 73.0 78.7 52.2 79.4 58.3 0.7 16.0 0.9 12.7 33.8 12.6 18.7 11.6 16.2 29.5 12.6 11.5 11.8 0.7 24.3 27.8 24.1 15.2 15.0 39.7 41.2 42.7 52.4 39.5 43.9 46.6 44.4 43.7 42.6 42.1 44.4 25.4 6.4 6.3 5.5 38.0 59.5 65.3 148.8 32.5 12.5 51.7 56.5 20.8 48.6 50.3 62.5 2.1 32.5 19.1 200.1 162.4 65.1 44.5 37.8 39.0 36.9 71.3 46.9 3.5 68.1 105.5 44.2 63.7 25.1 45.2 43.2 28.5 272.2 96.0 13.5 5.4 225.4 87.5 44.5 50.6 43.6 38.8 39.0 62.2 2.8 28.0 53.1 21.6 6.6 12.8 56.4 125.8 30.9 80.5 128.7 253.7 479.9 26.1 10.0 26.3 32.0 39.0 183.8 16.4 69.6 68.6 21.6 19.4 123.4 190.7 74.8 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNAB2 "AKR6A5, HKvbeta2.1, HKvbeta2.2, KCNA2B" ENSG00000069424 "Potassium voltage-gated channel subfamily A regulatory beta subunit 2" Q13303 1 5990927-6101193 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 188.3" "Cell type enhanced" "Detected in many" "dendritic cells: 50.3;Excitatory neurons: 67.8;Hofbauer cells: 63.6;Inhibitory neurons: 49.2;Kupffer cells: 86.2;Macrophages: 51.3;Melanocytes: 64.0;NK-cells: 51.5" "Cancer enriched" "Detected in all" 7 "melanoma: 29.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 278.8;JURKAT: 142.7;U-937: 289.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001975 Enhanced NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 10: Brain - Neuronal signaling" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB001975: " "unprognostic (6.60e-2)" "unprognostic (2.33e-2)" "unprognostic (3.97e-3)" "unprognostic (2.30e-2)" "unprognostic (1.76e-2)" "unprognostic (8.18e-3)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (4.85e-2)" "unprognostic (1.58e-2)" "unprognostic (7.71e-3)" "unprognostic (8.83e-3)" "prognostic unfavorable (3.50e-5)" "unprognostic (2.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.35e-1)" "unprognostic (5.24e-2)" 12.8 7.7 69.2 28.6 94.1 63.8 8.0 7.4 188.3 5.6 0.0 8.8 5.4 7.2 2.3 5.0 8.6 11.2 22.1 141.6 12.8 26.0 10.1 31.1 43.6 78.7 5.3 5.6 4.0 1.5 20.3 5.9 77.5 6.2 4.6 17.8 6.4 3.4 12.6 12.3 23.9 6.3 1.5 65.8 6.5 5.6 18.9 27.0 6.2 15.8 24.7 8.8 5.1 89.7 11.3 27.0 2.5 4.5 1.5 5.0 10.3 6.3 40.0 6.3 7.8 10.6 4.1 62.0 23.3 6.1 7.7 5.4 2.7 1.0 3.2 84.6 9.6 71.1 25.3 21.1 6.0 278.8 1.9 6.5 1.3 3.4 7.5 6.3 3.6 142.7 2.7 114.2 3.1 9.8 61.9 115.9 1.1 3.9 15.4 13.8 9.7 78.9 0.1 0.2 20.6 6.2 5.3 6.4 101.0 2.7 5.4 117.3 1.1 1.3 9.4 14.4 7.5 84.4 122.4 100.4 12.7 289.2 1.9 4.4 34.3 18.6 29.8 27.2 26.8 7.5 18.2 28.0 31.0 8.7 18.7 20.6 14.4 19.4 25.0 12.7 19.1 43.2 69.2 94.1 7.4 188.3 141.6 12.8 78.7 5.3 77.5 1.5 18.9 89.7 3.0 0.0 6.6 7.5 23.0 4.8 1.7 1.8 1.8 24.0 1.2 2.3 15.7 7.2 1.5 1.8 6.2 0.5 50.3 0.3 0.0 0.3 5.8 3.4 1.9 3.1 0.0 11.1 67.8 1.4 2.3 3.5 2.0 0.6 8.8 2.9 3.9 1.0 63.6 6.7 49.2 0.5 2.0 86.2 19.0 5.2 3.7 51.3 64.0 5.6 26.6 4.9 51.5 8.5 6.1 0.6 0.1 2.6 23.4 0.4 0.1 40.8 8.7 11.8 0.0 2.1 3.1 3.2 2.9 0.7 2.8 0.8 44.3 2.5 0.3 0.6 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 28.9;choroid plexus: 32.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Extravillous trophoblasts: 14.4;Inhibitory neurons: 8.8;Oligodendrocyte precursor cells: 18.1;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 14.3;MCF7: 5.1;T-47d: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.1 0.0 20.6 0.1 28.9 0.0 0.2 0.0 21.5 0.0 32.1 1.2 0.2 0.6 0.0 0.2 0.1 0.1 0.7 28.8 14.7 0.4 0.0 0.3 0.1 0.0 5.3 0.0 0.9 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.5 0.3 0.5 12.5 0.3 0.0 0.0 0.0 0.6 0.0 15.8 0.1 14.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 2.1 0.1 1.5 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.1 6.1 0.7 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.9 0.0 21.5 28.8 14.7 0.0 5.3 0.0 0.6 12.5 15.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 2.0 0.8 1.4 1.4 0.0 0.0 0.0 2.1 0.0 0.1 1.6 0.0 0.0 2.2 0.8 0.3 0.9 1.2 0.0 9.3 0.0 14.4 0.7 0.0 2.0 0.0 0.2 0.0 0.0 0.2 0.0 8.8 0.2 0.0 0.0 0.0 3.4 0.3 0.1 0.0 1.9 0.0 0.3 0.0 18.1 1.4 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 7.7 0.0 0.4 0.3 0.1 KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 25.5;skeletal muscle: 69.1;tongue: 25.7" "Cell type enriched" "Detected in many" 6 "Horizontal cells: 89.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 2.3;HeLa: 3.9;PC-3: 4.3;SCLC-21H: 4.8;SiHa: 2.5;SuSa: 5.2;U-2197: 4.2" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: AB_10602912" "unprognostic (3.81e-3)" "unprognostic (2.69e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (7.84e-5)" "unprognostic (2.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (4.91e-2)" "unprognostic (8.12e-2)" "unprognostic (1.16e-1)" "unprognostic (4.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-1)" "unprognostic (5.90e-2)" "unprognostic (9.70e-3)" 1.3 1.1 2.9 0.6 2.2 0.4 0.8 25.5 3.3 1.2 0.0 0.9 0.1 0.5 0.6 1.4 2.1 0.4 6.4 1.5 2.9 1.3 0.1 1.9 0.1 4.0 6.0 0.4 0.2 5.5 0.8 0.4 3.1 0.6 0.3 1.3 0.7 0.6 69.1 3.6 0.4 0.6 1.1 1.2 1.1 0.8 10.8 0.1 1.1 25.7 1.0 0.7 0.5 1.4 0.0 0.7 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 1.0 0.0 4.3 0.0 0.6 1.1 0.0 0.0 4.8 0.2 2.5 0.0 1.1 5.2 0.0 0.0 2.0 0.0 0.3 4.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.2 25.5 3.3 1.5 2.9 4.0 6.0 3.1 1.1 10.8 1.4 1.4 0.0 0.0 0.7 0.0 1.5 0.0 2.3 0.0 2.9 0.0 0.3 14.3 0.0 1.2 1.8 0.0 0.0 0.1 1.1 1.9 0.0 0.5 0.4 0.5 3.4 1.2 0.0 2.8 0.0 0.0 3.4 0.5 1.8 0.0 0.0 6.8 0.1 0.2 89.2 5.7 1.4 4.1 0.0 1.2 0.5 7.5 0.1 0.0 2.8 0.0 10.2 0.0 0.0 0.2 0.0 0.5 4.1 0.0 0.2 0.0 0.8 0.1 1.5 0.0 3.0 0.7 0.6 2.5 0.0 2.3 0.1 0.5 0.0 1.8 0.2 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCTD21 KCASH2 ENSG00000188997 "Potassium channel tetramerization domain containing 21" Q4G0X4 11 78171249-78188626 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041964 Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA041964: AB_10795647" "unprognostic (1.17e-1)" "unprognostic (5.45e-2)" "unprognostic (3.74e-3)" "unprognostic (6.40e-3)" "unprognostic (8.06e-2)" "unprognostic (2.48e-2)" "unprognostic (1.52e-1)" "unprognostic (6.82e-2)" "unprognostic (8.85e-2)" "unprognostic (1.37e-3)" "unprognostic (2.49e-1)" "unprognostic (1.31e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "unprognostic (4.70e-1)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" 7.3 13.4 14.4 6.2 13.6 3.5 4.4 13.1 14.3 5.8 8.7 6.5 5.0 5.0 9.2 9.6 6.2 7.9 6.3 13.7 14.3 5.5 15.9 6.7 5.4 14.7 16.3 13.7 3.5 5.7 5.9 7.7 15.0 4.2 4.8 4.3 5.8 5.2 8.5 4.9 4.5 7.1 12.4 4.6 4.5 4.0 14.6 5.9 11.2 7.0 6.2 7.1 5.9 14.7 5.2 11.8 6.7 5.0 23.8 16.9 4.1 10.1 9.6 7.1 7.1 11.1 7.8 5.0 9.9 11.4 9.5 10.1 6.5 8.4 7.3 6.9 3.9 3.8 15.4 9.8 13.2 2.4 4.7 16.4 15.4 15.5 8.8 14.8 11.0 6.1 8.1 4.5 9.7 7.3 3.8 7.3 3.0 19.0 8.9 5.0 5.1 3.1 8.3 9.3 4.6 7.1 6.4 4.6 4.9 12.1 10.6 2.6 12.9 11.3 11.0 30.0 3.9 8.6 9.2 4.8 5.9 3.9 6.4 2.0 5.4 7.5 0.9 6.0 1.4 0.6 1.4 1.7 3.7 1.4 1.3 1.0 8.3 1.4 5.1 0.8 1.1 2.2 14.4 13.6 13.1 14.3 13.7 14.3 14.7 16.3 15.0 12.4 14.6 14.7 1.9 0.0 2.7 4.6 0.7 1.8 1.2 1.5 0.6 1.7 2.4 2.2 3.5 5.7 2.0 0.0 0.0 1.2 0.6 2.8 1.9 1.5 0.3 1.4 2.5 2.3 0.0 0.0 4.1 2.2 1.1 2.8 1.1 1.9 5.7 7.0 3.6 7.4 2.3 6.7 3.4 1.3 0.0 3.1 1.1 0.5 4.4 1.3 1.8 4.7 2.8 1.0 0.0 4.0 4.2 2.5 1.7 9.1 1.0 1.9 2.3 2.7 1.1 0.9 0.0 1.2 2.9 1.5 2.7 3.6 1.4 1.9 1.8 3.8 1.7 2.1 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 162.3;pancreas: 85.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 105.8;Collecting duct cells: 90.1;Distal tubular cells: 80.3;Ductal cells: 43.3;Enteroendocrine cells: 64.1;Proximal enterocytes: 60.3;Proximal tubular cells: 79.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;OE19: 17.2;RPTEC TERT1: 44.8;SCLC-21H: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.1 0.0 2.2 1.1 2.1 0.0 25.3 0.4 3.6 11.4 2.8 7.8 25.5 4.2 1.0 0.2 8.0 24.7 0.2 2.0 0.9 162.3 27.7 1.6 0.5 0.6 1.1 0.7 85.4 0.8 0.6 1.1 1.0 7.0 4.2 0.1 3.6 4.8 0.0 1.4 16.1 0.4 0.4 0.2 11.0 2.4 1.3 1.3 31.8 0.0 0.1 0.2 0.3 0.8 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 9.6 0.2 0.0 5.2 0.0 0.6 0.0 0.2 0.1 0.2 0.0 0.9 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.0 0.4 0.1 17.2 0.6 0.0 0.0 0.1 44.8 0.2 6.6 0.1 0.0 0.9 0.0 0.2 4.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 0.4 3.6 2.0 0.9 0.6 1.1 1.0 0.4 1.3 0.8 0.1 0.0 4.4 0.0 1.3 0.0 0.9 0.6 0.0 0.0 20.3 10.8 0.4 105.8 0.0 90.1 0.0 0.1 0.0 7.9 80.3 43.3 7.0 8.3 1.5 0.3 64.1 0.0 0.7 11.8 9.3 0.4 14.8 15.6 0.0 0.0 0.0 10.2 0.3 0.0 0.3 22.0 0.0 0.3 0.0 14.7 0.6 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.7 21.3 0.0 0.0 2.2 60.3 79.1 0.0 0.0 0.0 0.0 0.3 3.2 7.9 0.0 0.0 0.5 0.9 0.3 28.9 0.5 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIFC1 "HSET, KNSL2" ENSG00000237649 "Kinesin family member C1" Q9BW19 6 33391823-33409896 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Early spermatids: 32.0;Erythroid cells: 62.3;Extravillous trophoblasts: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 1.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055997, HPA062674" Enhanced Approved Centrosome NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "HPA055997: AB_2683001, HPA062674: AB_2684829" "unprognostic (7.33e-2)" "unprognostic (1.28e-2)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (7.07e-8)" "unprognostic (6.34e-3)" "unprognostic (9.36e-3)" "unprognostic (8.58e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (1.83e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.17e-2)" "unprognostic (6.66e-2)" "unprognostic (1.48e-1)" "unprognostic (4.52e-1)" 1.1 1.1 0.2 10.6 0.3 39.7 2.2 0.3 1.2 2.5 0.4 8.0 8.8 1.8 0.2 11.7 0.8 1.5 0.6 0.7 0.3 0.8 1.0 2.3 24.6 0.4 0.7 2.0 0.7 0.3 0.6 5.5 0.5 0.9 8.2 0.4 2.1 0.2 0.2 9.8 8.1 4.1 0.2 5.3 4.7 12.3 0.6 47.5 0.7 0.4 24.9 2.7 3.9 0.5 133.5 47.9 120.6 124.2 5.2 8.1 64.0 82.5 48.4 122.6 104.6 80.6 53.3 120.2 38.3 41.5 102.0 88.1 87.1 60.7 79.7 114.3 60.3 93.9 71.6 73.5 0.5 96.0 75.7 2.5 4.7 73.2 38.8 13.8 64.2 87.5 76.0 112.3 81.0 86.2 125.7 103.2 47.5 67.6 48.4 129.7 110.7 61.4 38.4 42.8 100.1 57.2 54.3 91.9 44.1 51.3 78.7 105.4 32.2 74.6 104.6 56.2 128.9 58.2 132.4 126.1 18.8 94.8 101.0 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.6 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.0 1.6 0.5 0.2 0.3 0.3 1.2 0.7 0.3 0.4 0.7 0.5 0.2 0.6 0.5 0.4 0.0 2.5 1.0 4.1 5.6 1.5 4.6 2.2 0.4 2.8 2.2 0.5 0.0 1.9 0.0 0.0 18.7 3.7 8.8 0.0 0.7 32.0 2.7 1.9 2.4 0.0 62.3 0.3 0.0 39.6 4.2 4.1 6.1 1.3 15.0 1.8 0.3 14.3 0.0 0.3 8.0 2.0 2.4 9.8 12.0 0.3 4.7 3.6 1.0 3.1 0.3 0.0 1.0 0.6 0.3 2.1 0.7 12.0 0.9 2.1 0.7 0.8 0.5 0.0 2.5 7.5 13.9 9.6 14.4 3.7 6.7 5.7 0.6 12.1 3.1 KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 149.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Skeletal myocytes: 9.8;Smooth muscle cells: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CAPAN-2: 1.6;EFO-21: 1.5;REH: 1.4;RH-30: 4.5;THP-1: 2.3" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Centriolar satellite" "HPA062095: AB_2684680" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (2.07e-4)" "unprognostic (6.02e-5)" "unprognostic (1.29e-1)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (8.17e-4)" "unprognostic (2.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.06e-1)" 3.8 0.1 0.2 0.1 0.2 0.0 1.4 0.5 0.2 2.2 0.2 1.0 0.2 1.2 0.0 1.0 1.3 0.5 14.3 0.1 0.4 1.0 0.1 0.9 0.0 0.9 0.8 0.4 0.1 0.0 0.1 0.3 0.3 1.0 0.1 0.1 1.0 0.8 149.1 0.8 0.7 0.7 0.1 0.2 0.5 0.1 0.2 0.0 0.6 15.2 0.0 1.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 1.4 4.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.2 0.1 0.4 0.9 0.8 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 9.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "dendritic cells: 19.2;Oligodendrocyte precursor cells: 36.2;T-cells: 15.9" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.4;GAMG: 2.8;HEL: 1.3;HeLa: 7.0;HSkMC: 1.2;SuSa: 1.3;U-698: 1.9" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" 0.2 0.1 1.3 0.3 1.4 1.9 0.1 0.7 2.1 0.1 0.2 0.5 0.8 0.5 0.1 0.2 0.2 0.6 0.0 1.3 1.7 0.1 0.5 0.6 1.7 1.7 1.1 0.1 0.1 0.0 0.0 0.1 1.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.3 4.0 0.6 0.2 1.3 0.4 0.1 0.0 0.8 0.1 0.1 2.1 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 1.3 7.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 7.0 0.0 0.0 0.1 8.7 0.6 63.1 0.0 0.0 0.0 3.6 1.3 1.4 0.7 2.1 1.3 1.7 1.7 1.1 1.2 1.3 1.3 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 0.1 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 1.9 0.0 0.0 1.0 36.2 2.3 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.1 KLRC4 NKG2-F ENSG00000183542 "Killer cell lectin like receptor C4" O43908 12 10407382-10409757 "Predicted membrane proteins, Transporters" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 9.4" "Cell type enhanced" "Detected in some" "dendritic cells: 22.2;NK-cells: 8.2;Plasma cells: 4.7;T-cells: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 20 "gdT-cell: 8.2;memory CD8 T-cell: 5.9;naive CD8 T-cell: 6.7;NK-cell: 4.7" "Group enriched" "Detected in many" 59 "NK-cells: 4.7;T-cells: 8.2" "Cell line enhanced" "Detected in some" "HeLa: 5.5;SuSa: 1.8;U-698: 1.7" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (3.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.60e-1)" "unprognostic (7.00e-2)" "unprognostic (1.55e-4)" "unprognostic (1.89e-2)" "unprognostic (1.52e-1)" "unprognostic (3.32e-1)" "unprognostic (2.92e-1)" "unprognostic (4.36e-1)" "unprognostic (3.44e-7)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (5.51e-3)" 0.8 0.7 2.0 2.3 2.1 1.7 1.5 0.9 2.0 0.6 0.2 1.2 1.3 0.8 0.6 0.8 0.5 2.2 0.3 1.6 2.0 0.2 1.2 1.8 4.7 2.2 1.6 0.4 0.1 0.0 0.1 0.5 1.8 0.4 1.3 0.1 1.1 0.1 0.0 0.1 2.6 0.5 1.2 9.4 2.3 0.6 1.9 0.6 0.7 0.0 3.2 0.6 0.5 2.8 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.3 0.0 0.0 5.9 0.0 0.0 0.0 6.7 0.1 4.7 0.0 0.0 0.0 1.8 2.0 2.1 0.9 2.0 1.6 2.0 2.2 1.6 1.8 1.2 1.9 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.4 0.0 0.0 0.4 0.0 8.2 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.2 0.0 0.1 KPNA7 IPOA8 ENSG00000185467 "Karyopherin subunit alpha 7" A9QM74 7 99173572-99250075 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "stomach 1: 3.6" "Cell type enhanced" "Detected in some" "Ductal cells: 5.7;Gastric mucus-secreting cells: 5.1;Pancreatic endocrine cells: 11.7;Respiratory ciliated cells: 4.4;Urothelial cells: 11.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 3.8;CAPAN-2: 2.8;OE19: 2.8;SK-BR-3: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA031395 Uncertain NA NA "Cluster 4: Stomach - Digestion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA031395: AB_10601584" "unprognostic (7.38e-2)" "unprognostic (7.99e-2)" "unprognostic (2.23e-1)" "unprognostic (8.44e-2)" "unprognostic (8.37e-2)" "unprognostic (9.35e-2)" "unprognostic (9.77e-2)" "unprognostic (2.25e-2)" "unprognostic (2.30e-1)" "unprognostic (3.23e-1)" "unprognostic (7.94e-3)" "unprognostic (5.89e-2)" "unprognostic (2.28e-13)" "unprognostic (2.21e-2)" "unprognostic (1.23e-1)" "unprognostic (3.54e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.7 0.0 0.5 1.8 0.4 0.0 0.0 0.2 0.1 0.5 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 5.7 0.0 1.3 0.1 0.0 0.0 0.0 0.8 3.1 0.1 0.4 5.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 11.7 2.2 0.0 0.1 1.9 0.1 0.0 4.4 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 11.4 KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6940.5" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 35588.3;Suprabasal keratinocytes: 11677.1" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 5910.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4065.2;HBEC3-KT: 2003.9;hTCEpi: 2448.6;hTERT-HME1: 794.2;U-2197: 696.0" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 36.3" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1600000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "CAB000134: , HPA000452: AB_1079177, HPA000539: , HPA023040: AB_1852201" "prognostic favorable (2.66e-4)" "unprognostic (1.64e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (1.02e-2)" "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (1.35e-1)" "unprognostic (1.00e-2)" "unprognostic (5.74e-3)" "unprognostic (1.49e-8)" "unprognostic (8.91e-2)" "unprognostic (2.00e-1)" "unprognostic (8.80e-3)" "unprognostic (1.22e-2)" 15.8 1.2 0.0 0.0 0.0 2.7 332.7 0.0 0.0 412.0 0.0 1.7 0.0 0.9 0.0 1304.2 1.7 0.0 3.5 0.0 0.0 0.8 2.5 1.7 0.0 0.0 0.0 1.3 2.9 0.0 4.3 2.2 0.1 29.1 0.0 0.0 702.1 3.8 15.9 6940.5 2.1 0.1 0.0 0.9 1.7 1.5 0.0 186.7 2.3 0.0 262.3 0.7 846.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.8 0.1 0.0 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.0 4065.2 0.0 2003.9 0.2 0.0 0.0 0.1 1.6 0.0 0.1 0.2 2.5 0.1 2448.6 3.0 794.2 0.0 0.1 0.0 0.5 3.6 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.6 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.0 0.3 9.1 1.7 696.0 0.0 0.9 0.0 0.0 3.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.5 35588.3 1072.7 181.5 2407.4 0.0 103.5 740.9 0.3 0.0 6.0 0.0 0.0 17.9 3.2 7.3 0.0 0.1 0.0 0.1 0.0 129.0 0.0 0.0 0.0 0.0 127.0 116.5 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.4 0.0 0.0 1833.4 0.0 0.0 9.3 1990.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.5 0.0 9.9 702.0 96.8 0.0 2.3 0.0 0.0 0.0 96.3 0.0 0.1 83.2 11677.1 2.5 62.1 0.1 2.3 100.0 KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 382.1;skin 1: 949.4;urinary bladder: 632.2" "Group enriched" "Detected in many" 5 "Basal prostatic cells: 13196.1;Prostatic glandular cells: 5931.6;Urothelial cells: 8499.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 3317.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "hTCEpi: 20287.9;SiHa: 8539.7" "Not detected" "Not detected" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 610000000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Intermediate filaments" "CAB000029: AB_2133155, HPA000452: AB_1079177, HPA000453: AB_1079176, HPA000539: , HPA045062: AB_2679204" "prognostic favorable (4.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (3.65e-3)" "unprognostic (4.46e-2)" "unprognostic (4.34e-1)" "unprognostic (4.36e-3)" "unprognostic (1.32e-2)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.82e-1)" "unprognostic (1.77e-1)" "unprognostic (2.20e-1)" "unprognostic (3.89e-1)" 5.1 0.4 4.9 0.8 5.3 2.8 382.1 3.5 5.8 102.2 3.5 2.0 0.8 4.3 14.1 320.4 6.9 1.9 2.7 6.3 3.3 3.1 0.6 9.8 0.3 3.5 3.4 0.9 2.6 0.5 6.6 7.0 3.5 132.4 0.3 0.3 263.2 116.1 0.9 949.4 0.6 1.0 3.4 0.4 2.3 4.5 3.3 142.7 1.6 0.0 97.8 632.2 212.3 4.7 212.5 0.2 0.0 0.0 0.8 0.9 48.8 1.9 0.4 2.8 2.7 16.8 1.9 1.0 14.7 0.2 0.4 2101.7 0.1 2129.1 1.9 0.3 1.6 2.0 910.8 2.0 0.5 1.9 2.2 0.4 20287.9 1.3 1539.9 0.0 1.0 0.0 1.0 1.5 0.4 0.7 0.7 0.3 0.4 237.2 0.0 0.7 3.1 1.7 0.8 770.5 0.3 0.2 8539.7 3.8 0.9 4.8 0.3 1.4 0.8 0.0 401.5 0.2 1.0 0.9 0.4 3.1 1.4 77.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 5.3 3.5 5.8 6.3 3.3 3.5 3.4 3.5 3.4 3.3 4.7 5.6 22.4 7.2 0.3 0.5 139.6 13196.1 338.0 327.8 0.2 158.4 792.8 0.1 0.0 415.8 36.8 0.0 21.5 3.8 0.9 0.0 567.7 0.4 116.9 13.5 54.5 1.8 0.0 3.2 202.1 148.5 87.9 0.0 134.1 3.8 0.0 0.0 0.0 3.8 20.2 0.5 0.6 36.7 0.0 14.1 1.6 2.1 37.5 10.6 3.7 6.7 0.0 0.0 0.5 1.4 1754.5 2.5 212.5 0.0 5931.6 0.1 0.4 100.1 0.0 0.0 0.9 101.0 0.3 0.4 48.2 124.3 5.7 60.8 3.1 0.8 8499.3 KRT9 "CK-9, EPPK, K9" ENSG00000171403 "Keratin 9" P35527 17 41565836-41572059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.4;Breast myoepithelial cells: 2.9;Extravillous trophoblasts: 2.2" "Cancer enriched" "Detected in some" 6 "melanoma: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.0;HaCaT: 16.8;U-2197: 3.0;U-937: 5.3" "Region enhanced" "Detected in many" "basal ganglia: 25.1" "HPA007261, CAB037322" Supported NA NA 24000000000 "Cluster 63: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB037322: , HPA007261: AB_1079182" "unprognostic (2.13e-2)" "unprognostic (5.08e-2)" "unprognostic (4.97e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (5.92e-7)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.5 0.1 0.1 0.1 0.0 0.0 0.2 0.0 12.1 0.0 0.0 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 5.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.9 0.0 0.0 0.0 0.1 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.0 0.1 0.2 LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.6;ovary: 18.6" "Cell type enhanced" "Detected in many" "dendritic cells: 36.7;Leydig cells: 39.1;Peritubular cells: 69.2;T-cells: 63.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cell line enriched" "Detected in single" 151 "HDLM-2: 147.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" NA NA 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002301: AB_564101, HPA013967: AB_1846277" "unprognostic (9.39e-2)" "prognostic favorable (3.89e-4)" "unprognostic (8.88e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (8.85e-2)" "unprognostic (4.63e-3)" "unprognostic (1.94e-2)" "unprognostic (1.97e-3)" "unprognostic (8.71e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (4.62e-11)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" "unprognostic (8.19e-3)" 1.7 0.4 0.3 7.3 0.2 1.5 0.9 0.4 0.7 3.8 4.3 4.5 3.3 6.1 2.8 1.3 3.8 1.2 1.5 0.3 0.4 1.0 2.6 2.5 16.2 0.6 0.3 18.6 0.2 0.1 0.7 0.4 0.5 2.6 2.0 0.8 1.1 7.0 0.2 0.4 5.9 1.9 0.7 23.6 2.1 3.4 0.4 1.6 0.8 0.3 10.9 1.6 3.4 0.5 0.1 0.6 0.8 0.5 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.5 0.0 0.0 0.5 0.1 0.0 147.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.3 0.1 0.2 0.4 0.2 0.5 0.5 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 10.0 0.0 2.4 11.0 0.0 0.0 0.7 4.2 0.0 0.0 0.0 0.2 2.0 1.1 0.3 0.2 0.4 0.7 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.5 7.7 0.0 3.3 0.0 1.4 5.1 1.6 0.7 9.6 5.9 12.6 15.5 1.6 0.0 4.3 0.0 10.4 0.3 36.7 2.6 0.0 0.2 0.4 1.2 4.9 4.5 21.7 1.7 0.2 0.0 0.2 7.1 1.5 1.9 0.0 1.0 4.2 3.5 11.5 0.0 0.1 6.3 0.0 4.2 6.2 1.5 39.1 3.3 1.8 0.0 3.4 1.4 2.1 0.0 0.0 0.2 0.8 69.2 10.2 2.4 0.7 0.3 0.3 6.7 6.6 5.9 4.9 0.5 2.4 4.5 3.0 0.1 63.6 0.2 2.9 0.6 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 LBHD2 ENSG00000283071 "LBH domain containing 2" A0A0U1RRK4 14 103084210-103090027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.9;testis: 3.0" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.3;Proximal tubular cells: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: Fibroblasts - ECM organization" 1.7 0.0 1.9 0.2 3.6 0.0 0.5 0.8 2.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 4.4 0.3 0.0 0.0 0.1 3.6 1.6 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.1 3.0 11.9 0.0 0.0 0.0 0.0 0.4 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 3.6 0.8 2.1 3.1 4.4 3.6 1.6 3.9 0.9 11.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1338.5" "Cell type enriched" "Detected in some" 30 "Hepatocytes: 458.3" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "ASC diff: 10.7;HSkMC: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001508, CAB025905" Approved "Secreted to blood" NA NA 25000000000 1300000000 "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" 58.2 0.5 0.0 24.2 0.1 0.5 6.6 0.0 0.2 4.6 0.0 0.5 0.0 2.6 0.0 0.1 0.6 0.2 3.3 0.0 0.0 8.7 1338.5 1.2 2.8 1.1 0.1 0.2 1.7 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.4 0.0 22.8 0.6 0.6 1.5 0.0 0.5 0.6 0.7 0.4 0.1 3.9 2.0 0.3 0.7 0.2 0.3 0.0 0.1 0.1 0.0 10.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 8.6 0.7 0.0 0.0 0.1 0.0 0.0 7.9 0.8 1.0 0.1 0.2 0.5 0.0 10.7 0.3 11.0 0.1 0.8 0.0 0.7 0.0 0.0 9.7 458.3 0.3 0.0 0.3 0.0 0.0 8.5 0.0 0.3 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 15.2 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.2;fallopian tube: 16.8;placenta: 19.0;skeletal muscle: 22.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 55.2;Endometrial ciliated cells: 35.7;Glandular and luminal cells: 84.4;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 105.0;Syncytiotrophoblasts: 26.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 37.1;SH-SY5Y: 104.5" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Nucleoplasm "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" 1.4 1.6 2.7 0.4 7.6 0.0 1.5 4.6 4.7 1.5 0.1 3.3 5.1 4.0 1.1 0.1 16.8 0.4 0.2 2.9 5.7 0.8 0.9 0.9 0.1 9.5 5.2 0.7 0.0 0.2 1.0 19.0 9.0 1.2 3.6 0.2 1.9 7.3 22.3 2.9 5.5 0.2 6.0 0.0 2.3 0.1 5.6 0.1 0.3 0.8 1.7 0.1 0.4 19.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.3 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.5 0.0 11.9 0.0 1.0 37.1 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 12.2 1.6 2.4 0.0 0.0 0.0 14.6 0.2 104.5 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 7.6 4.6 4.7 2.9 5.7 9.5 5.2 9.0 6.0 5.6 19.2 0.0 0.0 0.0 1.3 0.2 0.9 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 55.2 0.0 1.2 0.0 0.0 0.6 35.7 5.3 0.5 4.9 0.0 6.8 0.0 2.3 1.4 0.0 84.4 0.0 0.0 0.0 1.0 6.4 0.0 12.3 3.0 0.0 0.0 1.6 0.2 0.0 0.4 1.8 0.0 0.0 0.0 0.0 45.2 105.0 0.1 0.3 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 1.1 3.4 0.0 0.0 0.0 1.3 26.4 0.5 0.0 20.3 0.0 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;ovary: 2.1;testis: 2.2" "Cell type enriched" "Detected in some" 22 "Theca cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009814 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 52: Non-specific - Transcription" "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 1.3 0.8 0.3 0.0 0.4 0.0 0.7 0.9 0.5 0.0 0.7 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.1 0.0 3.2 0.7 2.1 0.0 0.0 0.5 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 2.2 0.8 0.2 0.6 0.1 0.0 0.3 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.9 0.5 0.2 0.6 3.2 0.7 2.0 1.6 0.8 1.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.3 1.0 1.2 0.1 0.0 6.5 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 143.2 0.0 0.0 LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.5;lymphoid tissue: 76.3" "Group enriched" "Detected in some" 5 "Kupffer cells: 64.1;Macrophages: 136.1;monocytes: 53.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.7;neutrophil: 137.2;non-classical monocyte: 311.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.2;monocytes: 311.7" "Cell line enriched" "Detected in single" 31 "RPMI-8226: 4.1" "Secreted to blood" NA NA 670000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" 7.9 1.3 0.2 36.9 0.2 43.5 1.9 0.2 0.9 0.7 0.6 1.8 0.0 1.0 0.0 0.9 4.1 1.7 2.5 0.3 0.2 1.8 3.8 22.2 0.5 0.6 0.3 0.6 0.9 0.0 0.9 1.6 0.5 1.4 1.2 0.0 1.2 0.0 0.7 0.3 2.8 6.9 0.3 76.3 2.1 0.3 0.4 0.4 1.0 0.0 0.4 15.7 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 128.6 0.5 0.0 252.7 0.3 0.0 0.0 0.0 39.2 0.1 0.0 0.0 137.2 0.3 311.7 20.3 0.1 65.0 0.2 0.2 0.2 0.9 0.3 0.2 0.6 0.3 0.5 0.3 0.4 0.4 0.1 0.0 8.5 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 3.1 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.1 1.0 0.0 0.0 11.4 0.0 0.4 0.7 6.5 0.0 0.1 0.0 0.0 64.1 14.3 0.0 0.0 136.1 0.0 0.0 53.4 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.4 2.2 0.0 0.0 0.8 0.2 0.1 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 LMNB1 ENSG00000113368 "Lamin B1" P20700 5 126776623-126837020 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.0;lymphoid tissue: 49.2" "Cell type enhanced" "Detected in many" "Early spermatids: 92.5;Erythroid cells: 67.3;Extravillous trophoblasts: 68.2;granulocytes: 93.6;Late spermatids: 72.1;monocytes: 59.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005269, HPA050524, CAB079757, CAB079954" Supported Supported "Nuclear membrane" NA NA 2100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "CAB005269: AB_648156, CAB079757: AB_2665863, CAB079954: , HPA050524: AB_2681156" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" "unprognostic (4.96e-3)" "unprognostic (3.70e-2)" "unprognostic (1.61e-1)" "unprognostic (8.65e-3)" "prognostic unfavorable (3.08e-6)" "unprognostic (2.06e-2)" "unprognostic (6.62e-3)" "unprognostic (5.28e-2)" "unprognostic (2.13e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.33e-2)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" 4.2 1.6 1.9 26.6 1.8 34.0 2.9 9.8 2.1 3.7 0.5 14.9 11.2 2.8 0.5 14.2 1.8 3.4 1.5 1.6 3.3 3.5 4.9 6.0 34.8 2.9 2.3 2.2 2.4 0.7 2.0 6.7 2.4 1.6 13.0 6.4 3.4 1.6 1.0 8.6 14.2 3.5 2.1 13.3 7.9 2.2 2.3 49.2 1.6 1.4 29.2 6.8 4.8 1.8 132.7 43.4 131.6 126.6 3.3 9.3 170.6 60.6 17.8 66.1 71.3 113.4 107.2 229.4 103.2 21.4 31.5 72.4 90.9 42.1 72.2 162.9 112.1 147.5 49.1 67.2 1.4 176.6 95.6 3.0 0.9 35.2 16.0 12.8 54.9 92.0 87.1 86.3 46.6 109.7 322.8 347.5 99.0 54.1 60.0 152.6 259.4 93.1 36.6 59.6 151.4 80.3 98.4 41.7 36.6 45.2 76.2 202.0 46.9 48.7 132.0 36.6 131.3 56.8 46.4 197.3 25.0 247.1 73.8 1.4 14.4 4.8 2.1 5.6 1.6 4.2 4.3 2.8 15.3 2.9 3.1 2.8 9.3 2.4 1.5 4.6 12.4 6.4 1.9 1.8 9.8 2.1 1.6 3.3 2.9 2.3 2.4 2.1 2.3 1.8 3.4 0.0 4.3 0.3 20.1 5.0 1.9 2.0 8.0 6.4 4.3 5.1 1.6 4.3 3.3 0.0 8.4 39.4 56.0 7.7 1.9 1.8 92.5 3.9 4.8 8.8 6.1 67.3 6.8 0.8 68.2 8.1 11.7 7.6 93.6 23.9 3.6 3.1 21.8 5.0 9.1 19.3 0.0 13.1 17.9 72.1 2.1 27.9 1.8 1.9 59.5 3.8 13.4 5.5 1.1 1.1 8.4 0.4 50.6 1.1 3.8 2.1 1.9 17.5 0.0 2.5 7.3 3.4 8.9 27.3 5.4 4.7 34.2 3.0 35.8 1.4 LMO3 "DAT1, RBTNL2, Rhom-3" ENSG00000048540 "LIM domain only 3" Q8TAP4 12 16548372-16610594 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 93.7;intestine: 85.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Alveolar cells type 2: 210.2;Astrocytes: 293.8;Excitatory neurons: 226.2;Oligodendrocyte precursor cells: 112.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 32.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "ASC diff: 189.3;LHCN-M2: 91.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.67e-2)" "unprognostic (2.84e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.10e-7)" "unprognostic (3.62e-2)" "unprognostic (5.44e-2)" "unprognostic (6.56e-3)" "unprognostic (4.91e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-5)" "unprognostic (4.41e-2)" "unprognostic (1.61e-1)" "unprognostic (2.13e-3)" "unprognostic (4.83e-2)" 27.1 8.0 72.8 2.3 89.5 0.0 13.4 35.0 93.7 38.2 25.9 85.6 1.0 18.4 2.7 2.6 7.3 5.2 6.5 85.4 43.5 3.0 0.4 33.8 0.2 42.4 61.9 8.6 39.3 0.7 20.3 1.1 48.2 13.1 9.7 2.7 3.2 28.6 1.6 1.9 14.0 11.3 40.8 0.5 7.1 0.9 67.1 15.3 50.6 1.7 0.0 54.9 18.5 59.2 0.0 0.0 0.2 0.1 189.3 7.4 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.2 0.0 0.0 0.8 0.6 2.5 0.0 0.0 4.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 91.9 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.1 3.6 1.3 14.3 0.0 0.0 0.0 0.2 0.8 0.0 0.7 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.8 89.5 35.0 93.7 85.4 43.5 42.4 61.9 48.2 40.8 67.1 59.2 8.3 173.1 210.2 293.8 0.1 0.3 0.2 5.8 0.0 0.3 2.8 1.4 1.1 0.0 62.8 53.3 18.8 0.2 0.1 0.0 3.9 0.0 5.7 1.8 0.4 0.3 0.0 0.0 226.2 3.6 0.0 23.5 0.0 0.1 5.1 2.5 0.0 0.0 0.2 0.0 46.8 0.0 8.2 0.0 0.5 0.8 0.9 0.7 3.6 18.7 0.0 0.8 0.0 112.6 7.0 0.5 0.0 0.4 0.1 0.2 0.0 0.1 63.7 0.6 0.0 6.3 10.4 1.7 0.8 0.2 0.1 0.3 0.6 0.0 0.0 0.2 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LRFN1 "KIAA1484, SALM2" ENSG00000128011 "Leucine rich repeat and fibronectin type III domain containing 1" Q9P244 19 39306566-39320863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 32.5;Cone photoreceptor cells: 8.4;NK-cells: 11.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.9;HEK 293: 20.2;K-562: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (4.92e-3)" "unprognostic (2.00e-1)" "unprognostic (6.36e-4)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.87e-2)" "unprognostic (6.75e-2)" "unprognostic (4.25e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.45e-3)" "unprognostic (1.08e-1)" "unprognostic (0.00e+0)" "unprognostic (1.89e-3)" "unprognostic (2.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.78e-1)" 1.3 0.5 5.1 0.6 5.1 0.5 1.2 2.9 8.7 1.3 0.0 1.2 0.4 1.9 0.5 0.7 1.2 0.1 0.4 6.0 4.0 0.5 0.8 1.8 0.4 3.1 1.1 0.8 2.9 0.7 0.9 0.2 1.1 1.0 0.1 1.1 1.0 0.1 0.1 1.1 1.3 0.2 0.0 4.0 1.1 0.7 4.1 1.1 0.9 0.0 0.2 0.5 0.7 2.6 1.2 5.4 0.1 4.7 0.0 0.0 5.6 0.2 0.0 0.3 0.1 16.9 0.6 0.5 2.2 0.0 1.3 0.3 2.1 0.1 0.2 0.5 20.2 0.8 0.8 0.7 0.1 0.3 4.4 0.3 0.2 0.1 0.0 0.4 0.1 6.1 8.9 0.5 0.0 2.8 2.3 2.7 2.3 1.7 5.5 7.5 0.0 1.8 0.0 0.2 1.5 8.0 1.9 3.5 1.4 0.4 1.7 1.8 0.3 1.9 6.6 1.6 0.2 0.8 0.3 2.0 0.1 1.0 0.6 0.4 0.0 0.9 0.2 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.4 0.2 0.1 0.0 0.0 5.1 5.1 2.9 8.7 6.0 4.0 3.1 1.1 1.1 0.0 4.1 2.6 1.9 0.0 0.0 2.0 0.5 0.8 0.2 0.0 0.0 32.5 1.4 1.5 0.8 1.5 0.0 0.0 8.4 0.7 3.3 0.1 0.0 0.2 0.1 0.0 0.4 1.3 0.0 0.4 5.6 0.7 0.4 0.8 0.0 0.0 0.0 3.2 2.9 1.0 1.0 3.3 5.7 0.0 0.0 3.5 1.4 0.1 0.0 1.9 0.0 1.9 3.7 6.3 11.3 3.5 0.6 0.2 0.0 2.6 0.5 0.7 0.0 0.1 0.0 2.6 0.0 0.0 0.3 1.2 0.8 0.5 0.4 0.8 2.9 1.6 0.0 0.2 LRIG1 "DKFZP586O1624, LIG-1, LIG1" ENSG00000144749 "Leucine rich repeats and immunoglobulin like domains 1" Q96JA1 3 66378797-66501263 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 144.4" "Cell type enriched" "Detected in many" 5 "Astrocytes: 331.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.1" "Cell line enhanced" "Detected in many" "Daudi: 79.7;hTEC/SVTERT24-B: 55.2;U-698: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011846 Approved Approved Cytosol NA NA 78000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA011846: AB_2668545" "unprognostic (6.41e-2)" "unprognostic (4.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.58e-2)" "unprognostic (2.12e-2)" "unprognostic (2.28e-1)" "unprognostic (2.32e-1)" "prognostic favorable (3.01e-5)" "unprognostic (5.12e-1)" "unprognostic (7.86e-2)" "unprognostic (2.62e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (8.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.50e-4)" 31.0 1.8 33.1 17.0 29.2 4.0 27.2 15.1 21.0 29.9 0.0 38.6 16.8 21.9 3.0 13.5 26.7 20.9 37.0 21.4 26.7 3.6 11.2 17.6 7.9 29.4 39.2 17.1 144.4 5.2 6.5 4.7 17.2 24.8 14.7 5.0 19.2 7.2 37.2 11.7 13.4 30.5 14.3 3.9 36.5 12.5 51.0 3.5 16.2 32.9 9.6 5.9 5.2 17.7 1.4 1.3 27.6 0.5 7.6 4.8 2.8 4.9 26.6 4.6 14.0 23.6 0.3 79.7 13.1 2.2 6.1 0.0 5.5 10.0 10.1 0.0 16.8 0.0 4.1 2.0 1.8 0.7 16.7 6.0 5.4 55.2 9.0 18.8 24.3 0.3 0.3 0.0 1.0 3.6 0.0 0.1 22.8 2.3 0.0 14.1 8.7 3.7 5.1 0.0 3.9 1.0 4.6 4.1 0.2 4.6 25.6 6.7 8.2 13.9 6.3 27.9 12.9 6.2 3.2 59.5 24.3 0.0 5.0 0.0 0.0 0.3 0.1 0.0 0.6 0.1 0.4 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 1.1 0.1 33.1 29.2 15.1 21.0 21.4 26.7 29.4 39.2 17.2 14.3 51.0 17.7 12.5 38.5 50.2 331.1 4.3 11.3 7.8 8.0 14.2 2.1 51.9 35.8 32.0 11.5 25.0 0.0 8.4 0.2 5.8 9.6 1.9 5.6 1.6 29.1 9.7 9.2 26.5 0.0 10.6 17.1 0.1 17.1 19.9 58.8 1.3 14.9 6.4 20.7 2.0 8.4 15.6 26.2 12.2 1.9 7.7 2.1 11.5 2.4 10.6 57.1 1.7 39.8 0.0 37.7 58.3 6.0 10.2 17.3 8.7 15.6 5.7 1.2 33.7 6.8 0.0 65.5 19.9 1.6 20.0 8.9 11.5 0.1 15.2 2.1 22.8 5.0 LRRC1 "dJ523E19.1, FLJ10775, FLJ11834, LANO" ENSG00000137269 "Leucine rich repeat containing 1" Q9BTT6 6 53794497-53924125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 115.1;Late spermatids: 117.0;Oligodendrocytes: 138.8;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031603, HPA031604" Enhanced Supported Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031603: AB_10601753, HPA031604: AB_10601224" "unprognostic (2.90e-1)" "unprognostic (8.01e-2)" "unprognostic (9.59e-3)" "unprognostic (2.46e-2)" "unprognostic (7.04e-3)" "unprognostic (1.55e-2)" "unprognostic (2.19e-3)" "unprognostic (6.37e-2)" "unprognostic (7.02e-2)" "unprognostic (7.12e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.97e-1)" "prognostic favorable (2.21e-7)" "unprognostic (1.74e-1)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (9.84e-3)" 14.0 2.2 8.7 5.1 13.8 2.9 13.3 10.1 11.2 13.2 13.7 25.5 17.3 5.1 7.5 18.2 8.5 7.8 4.2 9.2 10.4 7.7 0.8 7.6 2.7 13.9 10.8 4.8 8.8 22.6 7.9 11.1 14.2 8.7 25.4 7.1 16.7 6.7 1.5 22.5 18.1 5.1 10.9 1.5 14.8 14.5 11.1 13.9 15.3 1.4 10.7 14.5 18.0 24.1 45.2 5.7 6.1 10.9 1.6 0.8 42.8 6.1 12.3 5.2 7.1 49.4 21.7 6.4 4.9 3.9 9.7 21.7 47.9 19.4 6.6 7.9 13.8 3.9 4.5 33.5 15.2 4.9 2.9 1.6 15.8 0.4 11.5 8.1 9.4 23.1 0.9 5.8 2.9 19.7 33.6 0.6 4.8 33.5 4.2 6.8 10.2 3.3 14.1 57.4 15.7 1.5 7.3 31.7 9.9 15.2 20.6 5.0 4.3 3.9 12.6 0.2 5.6 5.8 4.9 4.6 4.4 6.7 4.8 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.3 0.5 0.1 0.1 0.0 0.7 0.0 0.3 0.0 0.0 8.7 13.8 10.1 11.2 9.2 10.4 13.9 10.8 14.2 10.9 11.1 24.1 19.8 41.7 3.9 53.2 2.9 52.6 25.5 16.3 12.0 43.0 16.0 8.1 3.5 11.5 20.6 16.5 4.2 54.5 2.3 115.1 7.9 20.5 88.5 38.8 9.4 18.8 18.0 1.7 11.9 15.6 62.0 5.9 26.0 74.3 5.7 10.5 8.6 0.3 5.1 8.4 21.9 23.6 12.2 0.6 7.1 117.0 9.3 1.3 10.6 26.2 2.5 32.7 6.2 35.2 138.8 29.5 62.5 10.1 4.2 18.5 32.5 12.3 14.1 3.0 6.6 3.5 3.7 27.3 7.3 19.9 52.7 107.4 3.1 1.6 24.5 32.5 LRRC31 FLJ23259 ENSG00000114248 "Leucine rich repeat containing 31" Q6UY01 3 169839172-169869935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.7;salivary gland: 6.5;stomach 1: 10.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 8.9;Enteroendocrine cells: 10.3;Intestinal goblet cells: 23.5;Paneth cells: 6.0;Undifferentiated cells: 5.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.9;HAP1: 1.4;OE19: 8.8;RPTEC TERT1: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA058013 Approved Nucleoplasm,Cytosol NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm Cytosol "HPA058013: " "unprognostic (5.15e-2)" "unprognostic (5.75e-2)" "unprognostic (2.68e-2)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.90e-2)" "unprognostic (4.40e-2)" "unprognostic (7.90e-3)" "unprognostic (2.49e-2)" "unprognostic (1.64e-2)" "unprognostic (3.20e-4)" "unprognostic (3.14e-1)" "unprognostic (2.61e-1)" "unprognostic (2.27e-1)" "unprognostic (5.96e-3)" 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 1.4 0.0 17.5 8.4 0.1 0.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 5.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 21.7 0.1 6.5 0.0 0.0 0.0 9.6 0.4 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 1.0 0.3 0.0 10.3 0.0 0.3 0.0 0.0 0.0 3.1 3.0 0.0 0.0 0.0 2.4 0.1 0.0 0.2 23.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 6.0 0.0 0.0 0.1 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.4 LRRC46 MGC16309 ENSG00000141294 "Leucine rich repeat containing 46" Q96FV0 17 47831634-47837719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "fallopian tube: 78.4;testis: 54.3" "Group enriched" "Detected in some" 6 "Early spermatids: 143.1;Endometrial ciliated cells: 166.7;Late spermatids: 61.5;Respiratory ciliated cells: 225.8;Spermatocytes: 125.7" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 11.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 3.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA021882, HPA074893" Enhanced Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA021882: AB_1853320, HPA074893: AB_2732271" "unprognostic (1.06e-1)" "unprognostic (6.01e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.11e-4)" "unprognostic (1.40e-1)" "unprognostic (2.81e-2)" "unprognostic (4.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.21e-3)" "unprognostic (3.63e-2)" "unprognostic (2.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (2.14e-1)" 0.2 0.3 1.4 0.1 1.0 0.5 0.3 1.3 0.8 2.6 4.2 0.1 0.1 1.1 0.9 0.2 78.4 0.2 0.3 1.0 1.8 0.7 0.5 4.8 0.3 2.4 6.7 0.3 0.5 0.2 1.7 0.1 3.2 0.5 0.0 2.3 0.3 0.3 0.1 0.1 0.2 0.0 3.1 0.5 0.2 54.3 1.3 0.4 0.9 0.0 0.1 0.2 0.2 2.1 0.7 2.8 0.3 1.4 0.2 0.4 0.8 0.1 0.8 0.7 1.3 1.1 0.7 0.2 1.7 0.3 0.8 0.7 0.3 0.6 1.1 1.1 1.2 0.6 0.9 0.5 0.1 0.0 0.7 0.0 0.5 1.7 0.5 0.2 0.1 0.4 0.6 0.4 1.1 1.2 1.1 0.0 0.1 0.2 0.4 0.9 0.0 0.6 1.4 0.5 1.2 0.9 0.3 0.0 0.5 0.1 3.6 0.1 0.2 1.6 0.5 0.2 0.2 0.6 0.5 0.5 1.1 0.2 0.1 1.3 0.4 0.5 0.0 0.5 0.0 0.1 0.0 0.3 0.7 0.1 0.2 0.0 0.5 0.8 0.4 0.3 0.0 0.1 1.4 1.0 1.3 0.8 1.0 1.8 2.4 6.7 3.2 3.1 1.3 2.1 0.3 0.0 2.3 0.0 0.5 0.0 0.3 9.7 0.0 0.6 0.7 0.9 0.5 1.5 21.9 5.5 2.1 0.1 0.4 0.2 0.0 0.9 143.1 166.7 1.9 0.4 0.0 0.4 0.2 0.0 0.5 1.2 0.0 3.3 0.0 0.3 0.0 0.1 0.5 0.0 0.3 0.6 12.2 0.0 0.3 61.5 2.8 1.0 0.0 1.0 0.8 1.0 0.0 0.0 0.4 0.6 1.1 1.9 0.2 0.3 0.1 1.4 225.8 7.0 0.0 0.4 3.7 125.7 4.2 0.0 0.0 0.1 0.7 0.3 0.0 0.2 LRRC56 "DKFZp761L1518, FLJ00101" ENSG00000161328 "Leucine rich repeat containing 56" Q8IYG6 11 537527-554912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.3;testis: 22.3" "Group enriched" "Detected in many" 6 "Early spermatids: 68.0;Late spermatids: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 1.3;Karpas-707: 2.4;SK-BR-3: 1.6;T-47d: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038728 Approved NA NA "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "HPA038728: AB_10671864" "unprognostic (2.77e-2)" "unprognostic (9.54e-3)" "unprognostic (1.28e-2)" "prognostic favorable (7.39e-4)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (2.29e-2)" "prognostic favorable (6.19e-4)" "unprognostic (2.65e-3)" "unprognostic (1.86e-1)" "prognostic favorable (6.32e-4)" "unprognostic (1.17e-1)" "unprognostic (7.89e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.56e-1)" "unprognostic (1.52e-3)" 0.8 0.8 0.5 0.1 1.9 0.2 1.6 0.3 0.5 2.4 0.6 1.7 0.1 0.9 1.3 2.7 6.4 0.0 0.5 0.8 0.3 3.2 1.6 2.9 0.0 0.5 0.3 1.8 2.4 0.0 12.3 0.0 0.1 3.7 0.0 0.1 2.0 0.3 1.2 2.5 2.2 0.0 0.4 2.2 2.1 22.3 0.6 0.1 2.7 0.0 0.2 1.2 2.0 0.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.4 1.1 0.4 0.8 0.0 0.2 0.0 0.0 0.5 0.0 2.4 0.0 0.0 0.1 0.7 0.0 0.7 0.7 0.0 0.0 0.5 0.2 0.0 0.3 0.2 0.0 1.6 0.0 0.0 2.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 1.9 0.3 0.5 0.8 0.3 0.5 0.3 0.1 0.4 0.6 0.3 0.5 0.0 3.4 3.3 3.0 1.7 1.5 1.5 0.0 1.1 2.1 0.9 0.6 1.5 2.4 3.7 16.7 0.3 0.6 4.9 0.0 1.1 68.0 11.6 0.6 0.5 12.5 0.4 5.2 0.4 0.2 1.1 1.5 1.3 0.0 0.5 1.1 0.3 0.3 6.7 3.8 2.1 6.1 0.6 0.3 141.2 1.2 0.3 1.8 1.0 0.0 2.7 1.0 1.5 2.8 0.5 1.4 1.2 0.1 1.2 0.2 0.8 14.4 7.0 0.0 0.2 0.6 6.6 2.2 0.6 0.9 0.5 1.4 0.7 0.6 0.8 LRRFIP1 "FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP" ENSG00000124831 "LRR binding FLII interacting protein 1" Q32MZ4 2 237627587-237813682 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 322.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006979 Approved Supported Cytosol NA NA 580000 "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA006979: AB_1079282" "unprognostic (2.07e-1)" "unprognostic (2.99e-2)" "unprognostic (4.09e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.08e-2)" "unprognostic (3.99e-3)" "unprognostic (8.90e-2)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (2.69e-2)" "unprognostic (8.07e-2)" "unprognostic (7.64e-2)" 44.2 21.0 11.3 49.2 9.0 86.8 34.0 3.8 11.0 34.1 23.0 63.2 35.9 64.3 15.7 58.2 32.1 39.4 69.7 11.7 10.8 51.7 48.9 61.7 45.4 7.3 6.9 16.0 21.2 55.1 14.8 41.4 7.0 40.9 40.3 6.4 38.0 31.2 111.0 23.7 35.9 58.8 5.9 45.7 49.6 5.4 9.4 43.5 37.8 50.7 52.6 69.4 43.4 7.3 99.1 50.1 17.5 45.9 25.4 55.6 77.7 67.4 62.3 37.8 37.2 19.2 64.6 8.4 27.4 108.8 81.2 80.9 54.0 100.4 80.2 322.6 34.7 78.0 55.1 54.8 58.5 104.2 71.0 23.9 205.8 88.2 216.0 50.6 59.8 54.0 58.4 77.8 79.5 47.8 60.5 79.5 29.6 73.3 45.1 87.9 125.3 80.1 122.0 141.8 46.3 24.0 33.5 76.2 92.2 37.6 42.9 129.2 99.4 42.4 41.1 49.5 77.0 15.8 14.3 53.2 63.4 102.7 51.0 78.5 104.1 248.4 74.8 97.5 55.1 55.9 89.0 77.3 84.1 60.1 46.1 52.2 326.2 46.9 168.9 73.1 76.7 61.4 11.3 9.0 3.8 11.0 11.7 10.8 7.3 6.9 7.0 5.9 9.4 7.3 236.4 487.2 307.3 35.6 249.6 307.0 391.9 166.0 113.3 46.4 128.6 86.2 160.3 127.2 269.9 172.9 37.5 111.2 347.1 319.5 52.8 229.7 7.9 368.3 88.2 213.0 190.5 62.4 175.9 333.0 359.2 109.1 159.0 426.3 241.0 56.9 122.0 149.1 175.8 21.9 237.5 168.3 79.3 271.2 721.3 7.9 29.8 398.9 167.2 57.1 365.0 25.1 213.1 111.1 12.5 389.6 220.6 23.3 146.6 430.5 152.8 49.5 286.1 6.0 78.9 147.3 182.9 10.1 27.4 179.3 243.1 25.3 288.5 158.3 150.0 588.4 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 327.1;Leydig cells: 972.3;Peritubular cells: 624.4;Skeletal myocytes: 229.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 120.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" NA NA 9700000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" 138.5 48.5 11.3 22.3 10.9 8.3 98.8 1.7 13.3 334.6 9.6 144.5 59.2 309.6 44.7 100.6 246.8 39.3 401.9 10.7 14.2 64.7 37.4 242.5 24.8 16.2 10.3 315.2 37.2 22.6 75.9 38.3 16.4 253.6 38.2 3.7 82.8 126.3 63.0 73.0 135.4 74.4 11.3 80.5 125.3 78.5 14.2 12.9 173.2 156.7 14.0 188.6 374.5 15.3 19.8 21.3 41.7 56.5 15.1 16.0 6.6 7.7 24.9 7.8 6.4 6.4 43.8 22.4 34.9 13.1 12.4 26.3 10.6 26.8 2.6 61.0 3.3 7.3 53.7 2.4 49.4 3.0 23.1 19.9 21.7 15.6 27.8 41.0 4.9 21.6 46.7 120.3 1.9 19.7 3.1 1.3 4.9 56.1 24.9 51.9 1.1 35.6 3.9 1.7 1.8 17.4 28.3 21.5 7.4 6.4 11.9 11.3 20.4 1.3 81.4 2.6 16.7 26.8 24.9 7.1 35.1 28.5 20.4 0.0 1.5 0.4 8.1 2.4 5.5 3.5 7.7 6.5 2.7 2.0 3.2 3.4 0.3 3.0 1.3 5.0 5.5 2.3 11.3 10.9 1.7 13.3 10.7 14.2 16.2 10.3 16.4 11.3 14.2 15.3 84.7 6.4 14.1 2.0 11.6 57.6 30.9 62.8 56.3 60.4 13.0 18.2 15.5 17.2 18.5 22.0 0.0 1.5 12.7 38.2 1.9 6.3 11.1 14.8 154.7 29.9 4.2 12.4 8.1 4.7 2.6 327.1 37.2 24.2 10.2 13.5 102.4 3.3 7.5 40.4 11.3 42.2 6.1 6.4 39.6 39.0 972.3 13.9 58.7 15.0 9.5 3.5 16.5 2.0 14.0 6.9 16.6 624.4 16.5 23.6 97.7 0.3 7.1 3.2 59.2 229.2 52.8 50.7 36.3 38.2 29.1 2.6 24.9 10.2 36.4 27.2 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 743.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 392.2;Cardiomyocytes: 921.5;Cone photoreceptor cells: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA 880000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "Plasma membrane" "HPA038149: AB_10672471, HPA038150: AB_10672505" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.36e-1)" "unprognostic (4.57e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.30e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-3)" 127.4 55.7 475.5 50.4 483.4 16.1 98.0 433.2 406.8 118.0 215.5 193.2 35.1 111.7 69.7 90.7 94.7 52.9 380.9 351.2 408.7 88.3 66.0 105.0 35.0 567.9 490.6 90.0 71.4 31.4 56.1 64.8 509.2 92.7 47.6 149.0 71.4 88.1 743.9 120.6 80.6 94.5 526.1 64.0 93.9 80.0 552.3 42.1 61.1 491.0 37.8 135.5 115.2 533.2 121.9 95.7 117.1 89.3 168.6 298.5 49.5 222.6 241.2 184.1 204.9 81.3 74.4 102.3 50.7 337.9 172.8 79.2 151.4 201.6 204.7 148.7 63.8 69.3 102.8 106.0 228.6 48.6 53.9 251.4 246.4 224.0 271.6 167.1 245.1 70.6 91.2 115.3 146.9 69.1 69.5 58.9 70.9 59.9 195.0 36.6 110.1 128.1 118.2 100.1 46.4 72.3 171.0 68.3 118.6 163.0 50.1 44.8 334.5 172.7 132.3 182.9 144.4 80.4 66.9 47.8 222.2 58.6 167.3 10.5 6.6 3.7 15.6 10.6 7.5 12.3 10.2 12.7 7.1 11.5 4.9 7.6 2.6 13.4 27.3 10.8 13.0 9.7 475.5 483.4 433.2 406.8 351.2 408.7 567.9 490.6 509.2 526.1 552.3 533.2 147.9 70.5 48.2 124.4 45.1 74.8 55.4 53.1 42.7 392.2 34.7 36.2 921.5 48.6 53.4 80.9 625.5 33.8 54.6 43.7 27.4 97.8 116.2 78.2 143.2 110.4 28.8 21.6 63.7 65.3 81.0 105.5 39.8 93.4 27.8 81.6 50.0 57.3 38.0 47.1 71.2 31.7 34.6 28.3 50.5 38.8 77.0 40.0 78.2 95.5 72.0 82.8 47.4 77.9 167.2 92.0 28.0 103.0 47.2 89.0 37.1 39.2 43.6 97.5 72.3 149.0 119.0 65.6 64.3 58.7 69.6 22.4 60.5 137.4 39.5 44.7 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MAPK7 "BMK1, ERK5, PRKM7" ENSG00000166484 "Mitogen-activated protein kinase 7" Q13164 17 19377721-19383544 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 33.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 43.1;SuSa: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018561, HPA031031" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB018561: AB_2140544, HPA031031: AB_2673706" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.90e-2)" "unprognostic (4.38e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (5.67e-3)" "unprognostic (1.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-2)" "unprognostic (4.75e-2)" "unprognostic (1.23e-2)" "unprognostic (1.90e-1)" "unprognostic (5.71e-1)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 8.3 13.7 4.0 4.0 4.4 5.2 7.7 4.0 5.9 14.3 4.4 10.6 5.5 11.1 3.3 16.3 8.7 4.5 6.2 3.9 4.5 7.7 3.9 8.7 3.7 5.3 6.1 12.5 3.4 2.9 6.1 6.7 4.4 8.9 3.5 2.2 6.7 6.1 5.0 12.5 7.3 6.7 3.3 9.4 6.7 11.8 5.0 3.5 7.4 3.4 3.6 10.1 15.2 4.1 6.9 11.0 9.9 7.7 43.1 17.2 10.4 9.0 8.3 13.0 12.4 12.2 1.4 4.1 7.3 16.5 10.4 8.2 10.4 9.4 7.8 7.2 8.3 1.9 8.4 5.4 21.2 1.9 7.8 21.6 6.2 18.2 7.2 12.0 9.5 7.5 3.7 1.4 13.2 4.8 13.0 7.4 10.7 8.4 6.7 8.6 12.9 3.0 5.4 3.7 4.4 12.3 9.7 1.0 5.0 53.7 6.1 3.1 6.0 14.6 10.8 15.5 6.7 2.6 4.0 1.2 16.5 1.6 9.2 0.8 3.4 10.7 3.7 6.5 2.0 1.8 1.8 3.2 2.3 1.0 1.6 2.0 1.1 4.9 6.0 1.4 1.0 3.1 4.0 4.4 4.0 5.9 3.9 4.5 5.3 6.1 4.4 3.3 5.0 4.1 10.7 6.4 3.3 2.6 7.8 5.5 6.1 9.5 13.6 2.4 5.8 4.6 5.3 2.8 5.6 5.5 2.1 5.7 6.7 16.2 5.9 8.1 8.7 3.0 7.9 8.5 10.7 1.7 2.0 6.2 8.0 9.6 12.2 5.2 2.5 7.7 7.5 1.1 7.7 0.0 2.1 6.9 10.2 6.9 6.1 5.7 11.5 14.4 3.6 6.5 3.4 13.1 17.5 1.0 2.0 8.0 20.8 11.7 9.3 6.3 9.0 3.5 3.2 2.1 26.3 8.4 11.1 33.2 16.4 9.8 4.3 5.1 6.2 7.7 6.7 5.3 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARK1 "MARK, PAR-1C" ENSG00000116141 "Microtubule affinity regulating kinase 1" Q9P0L2 1 220528136-220664461 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 73.8;Excitatory neurons: 171.3;Inhibitory neurons: 170.1;Oligodendrocyte precursor cells: 167.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 11.3;RT4: 33.7;SuSa: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007421, HPA008061" Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA007421: AB_1079311, HPA008061: AB_1079310" "unprognostic (1.51e-1)" "unprognostic (6.27e-2)" "unprognostic (6.72e-2)" "unprognostic (3.63e-2)" "unprognostic (2.23e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.59e-2)" "prognostic favorable (2.23e-5)" "unprognostic (6.62e-2)" "unprognostic (4.27e-2)" "unprognostic (9.56e-3)" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (3.74e-2)" 6.3 1.8 6.9 1.4 7.1 0.0 4.9 6.4 10.0 4.6 8.4 5.4 0.4 4.2 9.7 4.8 3.3 1.7 8.0 7.4 6.7 2.3 0.3 3.1 0.5 6.4 6.8 1.7 0.9 2.4 6.9 1.1 7.4 3.0 1.2 9.3 3.7 4.0 2.2 2.5 2.5 3.9 5.7 1.3 2.8 6.9 6.5 1.4 4.3 3.5 1.9 5.3 5.1 6.4 0.4 0.0 5.4 1.1 0.0 0.0 1.8 1.6 2.2 1.8 2.5 0.0 0.0 0.0 0.0 0.0 2.5 2.5 11.3 6.0 1.0 0.0 8.4 0.0 2.3 0.0 0.0 0.7 0.8 0.9 4.7 0.0 3.0 0.8 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 8.1 5.5 1.8 0.0 7.4 0.0 0.0 33.7 6.4 6.2 0.3 0.3 0.5 12.2 0.5 0.0 0.0 0.0 2.4 4.0 7.1 0.0 0.0 0.0 1.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.1 6.4 10.0 7.4 6.7 6.4 6.8 7.4 5.7 6.5 6.4 3.2 0.0 0.5 73.8 0.5 3.4 2.6 10.0 13.1 28.6 1.6 3.8 21.9 0.0 4.7 3.7 31.3 2.1 0.0 0.7 0.0 1.6 7.3 19.3 6.4 3.4 9.0 0.0 171.3 0.0 2.3 6.3 2.6 35.5 0.0 13.6 3.3 0.0 0.3 10.1 170.1 0.4 4.1 0.3 1.5 3.6 2.1 0.2 0.0 15.0 0.0 12.3 0.0 167.9 45.9 0.1 0.0 6.4 0.6 4.8 1.5 0.2 4.1 11.9 0.0 6.9 17.5 17.4 5.1 13.1 3.3 1.0 0.4 1.1 0.9 4.8 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MASP1 "CRARF, MASP, PRSS5" ENSG00000127241 "Mannan binding lectin serine peptidase 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 120.0;heart muscle: 116.1;liver: 183.4" "Cell type enhanced" "Detected in some" "Astrocytes: 28.1;Cardiomyocytes: 38.1;Cholangiocytes: 20.0;Endometrial stromal cells: 30.6;Fibroblasts: 16.4;Hepatic stellate cells: 23.2;Hepatocytes: 65.8" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BJ: 133.3;BJ hTERT+: 498.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" No NA 8670000000 1900000000 "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" 6.3 3.6 9.4 1.3 9.4 0.0 2.8 12.9 7.0 120.0 4.9 57.5 1.9 88.4 3.3 11.1 17.7 5.1 116.1 10.4 27.0 4.8 183.4 6.0 1.0 19.2 16.5 2.7 0.2 0.3 1.0 9.0 15.3 46.0 5.6 0.0 2.3 52.2 37.5 6.3 7.5 44.4 22.2 0.8 1.6 0.5 14.6 0.2 3.2 18.9 4.3 9.9 61.5 32.0 0.0 0.0 0.3 0.4 15.7 17.3 0.1 133.3 498.3 1.8 0.9 0.0 0.0 0.1 0.0 40.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 2.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.2 0.0 0.0 5.4 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.4 12.9 7.0 10.4 27.0 19.2 16.5 15.3 22.2 14.6 32.0 1.1 0.0 1.8 28.1 0.2 2.9 0.1 0.2 0.0 0.0 0.0 0.0 38.1 20.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.9 0.7 30.6 2.0 0.0 0.0 0.2 0.0 0.3 16.4 0.0 0.7 0.0 0.2 23.2 65.8 0.4 0.0 0.9 0.0 0.0 1.9 3.7 7.5 2.5 0.3 1.8 1.0 0.0 0.0 0.0 10.1 0.2 0.0 0.0 0.7 0.1 0.1 0.0 2.4 0.0 0.0 0.0 5.4 4.5 0.0 0.0 0.2 1.7 0.1 0.5 5.1 0.0 0.1 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MCCC2 MCCB ENSG00000131844 "Methylcrotonoyl-CoA carboxylase 2" Q9HCC0 5 71587288-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 120.5" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 81.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA038300: AB_2675941, HPA038301: AB_10670661, HPA061546: AB_2684557" "unprognostic (2.39e-1)" "unprognostic (6.89e-3)" "prognostic favorable (3.62e-4)" "unprognostic (1.79e-2)" "unprognostic (1.89e-2)" "unprognostic (8.07e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.01e-1)" "unprognostic (3.37e-1)" "unprognostic (5.39e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-1)" "prognostic favorable (6.43e-8)" "unprognostic (1.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (3.47e-2)" 21.3 47.6 13.4 13.5 13.7 6.0 60.0 12.4 15.5 21.3 24.9 30.5 27.2 14.4 38.9 25.4 17.2 15.2 54.9 12.0 13.1 73.3 120.5 13.4 17.8 14.8 13.4 14.2 24.6 32.8 14.1 14.2 14.8 48.2 35.9 12.2 28.2 20.6 34.4 19.8 20.7 11.7 16.3 15.6 25.8 8.6 16.0 14.2 44.6 35.4 21.5 27.0 15.0 18.4 38.5 52.4 21.4 82.5 22.4 23.0 36.9 16.4 29.4 35.7 25.7 91.1 46.9 90.4 62.8 25.9 28.0 30.8 37.8 58.8 44.3 47.6 45.6 48.2 24.7 100.5 39.2 24.4 42.8 29.5 30.1 32.6 25.8 15.8 31.7 24.9 63.2 31.6 24.9 103.0 0.3 42.9 29.0 33.2 27.2 46.3 64.5 130.9 92.5 66.9 32.9 36.7 80.1 111.8 38.8 10.1 92.7 59.6 22.7 14.4 22.1 26.1 49.9 22.4 46.2 54.6 23.7 66.3 36.6 2.0 8.4 1.9 6.5 13.5 8.5 9.7 8.4 7.4 19.4 9.9 8.3 9.1 1.3 14.7 8.1 8.1 12.1 8.3 13.4 13.7 12.4 15.5 12.0 13.1 14.8 13.4 14.8 16.3 16.0 18.4 9.1 16.0 23.6 27.4 26.8 13.3 17.5 20.2 22.2 12.6 54.9 28.3 61.5 20.0 22.3 16.5 6.2 48.5 17.6 26.3 21.5 20.6 4.3 94.0 24.0 15.1 29.5 13.9 22.2 18.2 23.0 13.1 30.1 107.0 12.7 22.7 9.7 93.1 18.0 3.3 21.6 22.8 8.2 12.1 11.2 9.8 13.7 14.0 12.4 11.2 17.9 15.4 20.6 30.2 28.0 15.3 17.0 20.3 27.2 29.6 23.6 59.1 17.7 10.8 6.6 15.2 9.0 4.2 12.0 35.9 13.8 63.6 17.9 30.9 33.9 20.9 MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 134.5" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Bipolar cells: 70.4;Cone photoreceptor cells: 127.2;Endothelial cells: 69.7;Microglial cells: 92.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 35.9;SCLC-21H: 65.3;SH-SY5Y: 29.0;SK-BR-3: 43.9;WM-115: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" 44.1 7.6 39.0 6.3 35.1 0.9 39.5 134.5 76.1 16.5 0.4 17.5 11.3 19.4 5.1 14.1 17.8 13.4 52.8 32.3 27.7 17.5 7.7 19.0 6.8 51.3 40.6 4.8 18.8 10.3 44.4 8.4 57.6 17.0 13.7 20.0 32.7 8.5 16.5 24.8 18.7 7.1 29.1 3.6 18.1 2.0 49.3 7.1 27.6 16.3 6.0 15.0 16.9 47.7 0.0 1.6 14.9 4.8 0.5 0.9 2.1 0.0 0.0 0.0 0.0 3.8 2.2 0.1 3.7 1.5 2.5 0.3 3.8 0.0 0.0 0.0 7.4 4.3 0.2 9.1 0.5 0.2 3.1 1.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.2 14.4 5.6 0.5 2.6 4.0 35.9 0.0 0.2 15.0 7.9 5.9 23.6 65.3 29.0 0.0 43.9 0.1 2.4 26.0 0.1 0.6 0.1 12.5 5.4 0.0 7.5 0.4 2.3 23.9 1.0 60.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.4 39.0 35.1 134.5 76.1 32.3 27.7 51.3 40.6 57.6 29.1 49.3 47.7 138.3 0.0 8.4 4.6 2.6 5.5 3.4 1.5 8.0 70.4 12.9 10.0 44.3 12.8 4.6 9.2 127.2 0.0 1.2 10.8 7.9 5.6 0.4 9.9 1.6 69.7 26.5 0.0 58.5 2.6 0.2 7.1 23.0 18.7 1.3 11.2 13.6 3.4 1.4 38.7 60.9 54.6 8.2 2.2 4.6 1.5 0.6 2.5 8.8 92.8 0.1 5.4 0.0 40.7 75.0 1.7 9.8 1.2 3.0 4.2 4.0 10.4 7.2 23.9 0.0 5.2 11.9 0.7 2.7 4.2 9.1 0.1 2.1 0.5 7.4 4.1 MCIDAS "IDAS, MCI, MCIN" ENSG00000234602 "Multiciliate differentiation and DNA synthesis associated cell cycle protein" D6RGH6 5 55219564-55227315 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Transcription, Transcription regulation" Activator "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "parathyroid gland: 2.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Collecting duct cells: 1.8;Endometrial ciliated cells: 1.2;Respiratory ciliated cells: 3.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 4.9;HeLa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049981, HPA058073" Uncertain Supported "Nuclear bodies" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear bodies" "HPA049981: , HPA058073: AB_2683596" "unprognostic (3.11e-2)" "unprognostic (7.50e-4)" "unprognostic (2.48e-1)" "unprognostic (2.89e-2)" "unprognostic (1.76e-1)" "unprognostic (3.57e-2)" "unprognostic (2.41e-3)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" "unprognostic (3.63e-2)" "unprognostic (3.17e-2)" "unprognostic (4.67e-1)" "unprognostic (2.90e-3)" "unprognostic (4.17e-2)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "unprognostic (2.70e-2)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 2.9 0.4 0.0 0.6 0.0 0.0 4.9 0.0 0.0 0.4 0.7 4.0 4.4 0.0 0.4 0.0 1.2 0.7 2.9 0.2 0.0 0.2 4.0 0.0 6.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 1.9 1.4 0.0 0.0 1.6 0.0 0.1 0.2 0.7 2.2 0.8 1.5 0.0 1.7 2.6 1.3 0.0 2.1 0.5 2.2 0.0 4.0 0.4 0.0 0.0 3.4 0.2 0.1 3.3 4.2 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.7 0.0 0.9 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 197.8;Fibroblasts: 75.8;Granulosa cells: 93.3;Leydig cells: 53.7;Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 249.4;ASC TERT1: 249.6;HUVEC TERT2: 263.1;SH-SY5Y: 212.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" NA NA 210000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" 36.6 4.2 0.4 13.3 0.6 0.1 22.7 0.5 1.1 81.8 1.6 15.0 5.0 61.4 22.1 6.1 19.0 73.2 13.8 0.5 0.6 9.4 1.6 20.1 4.2 0.7 0.9 35.8 18.8 4.5 13.2 42.4 0.7 22.1 4.8 4.9 16.5 12.1 2.6 27.6 12.1 30.6 0.5 2.7 8.3 11.2 0.7 1.6 9.5 3.0 2.3 22.5 36.7 0.6 0.0 0.2 93.2 0.3 249.4 249.6 6.2 26.3 102.5 39.7 73.7 24.1 1.1 0.0 82.6 89.7 0.1 0.1 7.2 7.7 15.9 0.1 78.0 0.0 37.1 2.1 23.4 0.1 0.1 104.4 18.8 109.4 42.7 113.1 263.1 0.0 0.2 16.2 19.2 12.5 0.1 0.1 108.8 0.5 0.8 1.5 0.0 4.0 0.9 0.3 5.0 212.1 9.0 36.6 9.6 71.1 11.9 13.0 75.6 65.6 128.4 51.7 2.8 0.1 0.3 0.2 53.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.5 1.1 0.5 0.6 0.7 0.9 0.7 0.5 0.7 0.6 5.5 0.0 1.7 0.0 0.1 6.6 7.8 28.7 8.0 0.2 2.1 3.9 0.9 2.8 10.7 3.7 0.0 4.5 0.0 0.1 0.0 1.3 12.9 5.6 28.7 7.1 10.1 0.0 0.0 0.8 197.8 75.8 2.0 8.3 0.0 93.3 1.4 0.0 7.4 0.0 0.0 0.4 12.2 0.0 7.7 7.6 53.7 0.6 17.8 2.8 0.0 27.7 0.0 0.0 0.0 1.9 0.0 63.9 0.5 1.5 0.0 0.0 1.9 0.8 0.0 3.3 14.7 3.2 8.7 0.6 6.3 29.0 0.9 0.5 0.2 1.2 MFHAS1 "LRRC65, MASL1, ROCO4" ENSG00000147324 "Malignant fibrous histiocytoma amplified sequence 1" Q9Y4C4 8 8783354-8893630 "Disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Signal transduction inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 105.4;Glandular and luminal cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MOLT-4: 128.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051213, HPA054471" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA051213: AB_2681391, HPA054471: AB_2682498" "unprognostic (1.33e-1)" "unprognostic (4.46e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-1)" "unprognostic (1.95e-1)" "unprognostic (8.91e-3)" "unprognostic (2.70e-2)" "unprognostic (2.68e-3)" "unprognostic (9.23e-3)" "unprognostic (7.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.81e-1)" "unprognostic (2.01e-3)" "unprognostic (5.93e-2)" "unprognostic (4.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" 5.8 2.0 7.3 7.9 6.9 11.9 3.6 7.5 8.7 6.3 4.1 12.8 6.1 5.1 3.3 5.3 6.6 5.5 6.6 8.3 6.4 13.5 6.0 9.9 10.4 6.1 7.4 3.4 4.6 5.7 2.0 8.8 6.5 5.3 11.4 5.4 3.4 4.4 2.4 6.1 7.0 8.2 6.5 11.1 6.3 6.0 9.0 9.0 5.4 2.7 8.6 9.2 3.5 6.2 19.5 14.4 8.6 6.6 8.0 10.1 28.3 7.9 17.0 5.6 7.6 23.3 3.7 28.5 9.5 7.6 16.2 6.5 9.1 7.3 4.9 37.0 8.1 2.1 5.3 15.1 9.5 8.2 2.9 5.5 15.0 7.6 7.5 6.0 12.5 34.8 13.4 0.0 4.7 7.0 128.0 7.2 16.8 25.8 6.1 17.4 13.1 4.4 39.3 20.0 13.6 11.0 4.6 7.2 12.7 14.6 4.9 11.1 5.3 6.8 10.1 27.3 15.4 1.5 6.9 21.7 12.6 10.8 4.2 0.0 0.1 0.0 0.9 0.0 0.7 0.4 1.3 0.8 0.2 0.3 0.6 0.5 0.0 0.1 0.0 0.0 1.2 0.3 7.3 6.9 7.5 8.7 8.3 6.4 6.1 7.4 6.5 6.5 9.0 6.2 10.7 54.5 43.9 105.4 6.5 37.5 24.5 6.0 2.8 19.0 6.2 3.2 17.2 20.0 16.5 31.3 4.2 3.7 6.5 30.9 13.7 12.0 2.5 50.8 20.3 19.2 18.8 71.4 46.9 15.4 3.2 17.8 8.2 119.2 22.2 5.4 25.4 17.8 31.8 3.3 56.8 29.3 10.2 27.5 21.0 3.4 11.5 13.0 10.6 61.8 8.0 24.3 14.4 38.2 6.2 28.5 20.7 8.2 2.1 47.5 6.7 16.5 5.4 8.1 0.0 4.5 24.1 1.9 21.7 2.4 50.0 2.3 24.0 1.7 36.3 16.9 MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 228.0;retina: 116.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 151.3;Granulosa cells: 93.5;Horizontal cells: 208.6;Muller glia cells: 508.9;Theca cells: 474.8" "Cancer enhanced" "Detected in some" "renal cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 20.4;fHDF/TERT166: 30.7;HHSteC: 23.6;HUVEC TERT2: 61.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA015994: AB_2630370, HPA070835: " "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (3.11e-2)" "unprognostic (3.42e-2)" "unprognostic (1.02e-3)" "unprognostic (2.90e-2)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.31e-1)" "unprognostic (4.08e-2)" "unprognostic (1.47e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" 9.4 228.0 3.2 0.3 3.2 0.1 1.8 7.8 4.6 2.0 3.1 1.0 0.2 5.0 1.8 0.4 2.2 0.9 3.0 3.1 4.0 1.8 0.2 0.7 0.9 3.7 4.0 23.9 0.3 0.2 11.8 0.3 3.7 2.6 0.3 116.9 0.4 4.0 0.8 0.4 0.3 3.8 3.2 0.8 0.4 8.6 3.6 0.3 0.8 0.3 0.6 1.1 2.5 3.6 0.0 1.1 0.6 0.5 1.5 0.7 0.1 20.4 0.1 3.0 0.1 0.1 0.2 0.1 0.2 30.7 8.7 0.5 4.4 0.1 1.7 0.0 2.0 0.0 0.1 0.2 23.6 0.2 0.2 7.2 0.7 3.3 0.2 7.1 61.7 0.2 0.4 0.4 5.1 0.1 0.8 0.5 1.1 0.4 0.1 0.1 0.0 0.0 0.7 0.3 0.6 1.2 0.0 0.0 0.2 0.3 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.8 0.7 0.5 8.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.2 3.2 7.8 4.6 3.1 4.0 3.7 4.0 3.7 3.2 3.6 3.6 0.6 0.0 0.0 0.0 0.2 1.7 0.7 0.4 1.2 151.3 0.7 10.8 3.5 0.0 0.1 0.0 8.4 0.2 0.3 0.1 1.9 0.0 0.3 0.8 1.2 1.1 0.0 0.0 1.3 0.0 0.2 10.7 0.0 0.3 0.0 93.5 0.4 0.4 0.5 208.6 2.5 0.0 0.0 0.0 0.3 0.6 17.1 0.6 0.0 0.0 0.0 508.9 2.1 5.0 0.7 0.1 0.0 24.8 0.3 0.3 0.1 9.2 0.0 32.6 0.0 1.9 3.4 0.8 0.4 0.7 0.9 0.3 0.6 474.8 0.1 0.3 MGLL "HU-K5, MAGL, MGL" ENSG00000074416 "Monoglyceride lipase" Q99685 3 127689062-128052190 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 565.4;Distal enterocytes: 398.7;Pancreatic endocrine cells: 535.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 84.7;plasmacytoid DC: 89.8" "Group enriched" "Detected in all" 14 "dendritic cells: 89.8;granulocytes: 36.0;monocytes: 84.7" "Cell line enhanced" "Detected in many" "BJ: 209.1;BJ hTERT+: 238.6;LHCN-M2: 191.3;RPTEC TERT1: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011348, HPA011993, HPA011994" Enhanced Enhanced Nucleoplasm NA NA 100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA011348: AB_2668490, HPA011993: AB_1853914, HPA011994: AB_1853916" "unprognostic (1.84e-2)" "unprognostic (1.80e-2)" "unprognostic (2.14e-1)" "unprognostic (8.19e-2)" "unprognostic (1.15e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (3.61e-2)" "unprognostic (1.45e-1)" "unprognostic (8.83e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.63e-3)" "unprognostic (1.44e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-2)" "unprognostic (2.51e-1)" "unprognostic (2.11e-3)" 174.8 16.1 100.8 22.9 91.0 18.9 92.0 87.2 123.4 26.8 48.0 81.9 36.9 17.7 9.9 139.9 34.3 44.8 101.9 96.9 75.9 71.0 106.9 72.0 13.5 72.5 86.6 6.1 7.8 3.6 12.5 41.6 70.9 25.8 60.4 6.2 102.1 27.5 66.0 38.1 50.3 27.8 63.0 44.9 38.2 6.2 107.2 10.0 18.9 64.9 21.3 42.5 39.4 88.6 52.4 46.2 0.1 0.5 76.8 90.0 6.2 209.1 238.6 45.3 72.2 1.2 21.0 14.0 56.9 71.3 13.7 2.1 0.4 27.9 25.2 23.5 0.9 1.6 31.4 0.4 27.7 0.3 1.7 34.2 16.1 85.0 92.4 25.6 97.5 1.0 0.3 3.0 191.3 5.6 0.5 0.9 0.5 33.6 71.5 0.2 24.6 109.4 170.4 5.9 26.5 2.1 36.3 70.4 12.6 2.0 3.5 2.1 125.9 49.5 14.8 121.0 29.1 0.5 0.4 43.4 102.4 3.4 156.6 20.6 8.3 36.0 0.5 84.7 2.8 4.9 0.5 1.1 9.2 0.5 0.2 0.2 1.5 2.0 57.2 89.8 0.0 17.1 100.8 91.0 87.2 123.4 96.9 75.9 72.5 86.6 70.9 63.0 107.2 88.6 565.4 195.5 108.6 83.2 8.5 22.8 11.9 14.1 5.7 22.8 25.2 19.9 53.7 118.7 32.2 42.3 0.0 84.6 16.1 398.7 168.3 99.4 4.1 100.0 36.4 207.7 88.6 30.7 39.0 160.7 154.6 71.5 47.9 132.1 8.8 0.1 17.2 148.7 123.9 0.0 48.9 239.1 63.1 32.8 86.3 5.8 32.6 77.8 21.4 52.5 235.2 54.5 2.1 43.2 5.8 535.2 201.0 69.6 36.2 18.5 134.2 102.0 48.0 7.8 85.5 22.3 141.4 0.7 1.7 64.7 22.3 72.7 9.3 1.1 74.0 6.0 MGST3 GST-III ENSG00000143198 "Microsomal glutathione S-transferase 3" O14880 1 165631213-165661796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 2092.0;Syncytiotrophoblasts: 2371.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 793.9;OE19: 781.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053311, HPA077929" Enhanced Approved Nucleoplasm NA NA 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA053311: AB_2682108, HPA077929: " "unprognostic (1.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (7.78e-2)" "unprognostic (3.09e-1)" "unprognostic (2.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.90e-1)" "unprognostic (3.96e-1)" "unprognostic (3.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.60e-2)" "unprognostic (8.88e-2)" "unprognostic (1.89e-1)" "unprognostic (1.90e-1)" 260.2 163.3 218.0 57.7 224.9 126.2 196.5 245.4 273.1 96.6 214.1 219.6 358.6 91.9 520.6 97.6 112.3 114.4 770.2 232.6 258.0 254.3 166.8 117.5 48.9 239.5 228.8 118.0 90.1 139.1 86.1 173.2 248.3 113.4 217.8 89.9 164.0 114.8 568.0 87.8 301.6 118.8 227.4 54.4 163.0 64.2 230.3 51.9 142.9 578.7 47.7 107.2 90.0 240.5 178.2 128.0 150.0 106.1 533.4 312.1 653.1 158.1 244.2 119.1 205.2 126.8 219.1 10.9 117.1 198.6 117.8 204.7 36.2 155.2 118.5 793.9 94.5 27.1 84.7 60.4 144.9 45.0 58.9 284.2 107.5 178.0 62.3 239.4 202.0 54.2 72.3 65.6 233.6 37.0 48.9 97.4 292.3 781.6 165.8 44.8 63.0 22.2 599.8 159.4 104.1 134.2 148.7 181.1 313.2 308.4 139.1 215.9 174.7 135.8 82.6 92.9 110.8 49.7 37.0 5.8 239.8 109.7 92.3 44.8 172.9 81.2 107.2 150.2 107.9 79.3 130.5 117.3 138.0 78.2 81.4 89.1 32.3 62.3 195.0 58.2 125.5 185.0 218.0 224.9 245.4 273.1 232.6 258.0 239.5 228.8 248.3 227.4 230.3 240.5 915.1 102.5 164.8 48.3 87.6 228.3 251.8 603.8 111.0 144.6 177.0 267.6 670.1 301.7 292.6 557.3 266.9 2092.0 96.5 500.3 1001.8 380.2 18.2 325.6 132.6 268.0 152.8 785.4 75.8 425.9 1327.2 300.3 193.7 257.7 91.8 519.5 257.7 295.0 837.4 131.2 86.4 302.9 374.3 130.0 243.1 46.1 388.0 234.9 519.4 43.1 296.6 257.9 87.6 45.8 90.6 401.8 613.9 399.8 92.9 173.9 1004.1 1227.6 459.9 162.5 506.2 197.5 652.1 23.1 40.4 157.1 232.6 2371.4 123.1 288.6 440.7 237.6 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MID1 "FXY, OS, RNF59, TRIM18" ENSG00000101871 "Midline 1" O15344 X 10445310-10833654 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 129.3;Basal squamous epithelial cells: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 156.1;AF22: 132.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002878, HPA003715" Approved Uncertain "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA002878: , HPA003715: AB_1079384" "unprognostic (1.99e-1)" "unprognostic (2.81e-1)" "unprognostic (4.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.78e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (1.19e-1)" "unprognostic (3.61e-1)" "unprognostic (2.09e-1)" "unprognostic (2.87e-1)" "unprognostic (9.43e-2)" "unprognostic (1.25e-3)" "unprognostic (9.89e-2)" "unprognostic (1.49e-1)" "unprognostic (1.12e-3)" "unprognostic (5.88e-2)" 5.9 2.5 6.9 5.0 7.7 1.7 5.3 17.2 5.0 7.0 6.5 17.3 5.7 8.9 4.9 7.0 6.4 6.8 9.3 7.0 4.9 7.3 4.2 6.5 2.2 3.6 10.4 4.4 3.5 2.8 4.2 6.2 4.9 10.4 10.6 12.3 4.9 12.9 0.7 2.9 5.8 12.3 2.1 1.0 3.8 3.6 8.2 2.3 4.2 2.2 3.1 11.7 6.2 4.4 33.2 156.1 132.5 16.7 8.1 9.2 14.6 16.2 17.8 19.7 20.7 31.0 9.7 10.6 6.5 21.9 58.4 22.5 11.0 15.1 23.0 1.3 11.0 2.7 24.3 1.1 2.8 0.3 1.2 12.1 7.0 16.1 15.8 20.4 23.1 5.1 2.1 3.2 9.6 8.0 5.3 0.5 32.7 5.1 10.0 3.9 28.9 0.4 18.7 36.2 7.1 3.5 7.4 23.5 10.1 42.7 19.2 0.2 13.7 7.2 1.0 34.1 17.0 2.8 1.2 0.4 13.5 0.3 31.3 0.5 0.1 0.6 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.7 0.0 0.1 0.4 0.0 0.1 6.9 7.7 17.2 5.0 7.0 4.9 3.6 10.4 4.9 2.1 8.2 4.4 16.5 35.3 20.7 129.3 0.7 21.4 31.5 24.7 82.6 10.7 8.5 13.2 4.8 8.6 19.6 23.9 18.8 9.1 1.3 22.6 1.9 13.4 2.2 39.8 8.9 25.4 12.1 2.7 15.5 8.7 26.9 16.2 10.7 38.5 1.3 13.4 69.9 4.0 1.5 69.0 44.3 9.0 2.0 2.5 5.8 7.9 30.1 1.2 3.6 23.4 0.0 37.0 0.0 66.4 59.2 7.3 17.2 41.3 0.2 8.2 11.3 1.5 19.3 2.9 6.6 3.7 3.3 0.3 2.4 36.1 10.1 20.0 0.8 9.7 20.0 49.2 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4" "Cell type enriched" "Detected in some" 5 "Plasma cells: 18.5" "Cancer enriched" "Detected in some" 9 "testis cancer: 6.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 9.0;SuSa: 1.9;U-698: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA005662: AB_2667382" "unprognostic (4.09e-2)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.03e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (5.05e-2)" "unprognostic (7.40e-3)" "unprognostic (2.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.71e-13)" "unprognostic (1.54e-1)" "unprognostic (1.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.47e-2)" 0.1 0.1 0.3 1.0 0.2 0.2 0.2 1.2 0.3 0.1 0.2 0.7 1.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 2.4 0.3 0.2 0.2 0.1 0.6 0.0 0.2 0.3 0.1 0.6 0.1 0.2 0.2 0.0 0.2 0.7 0.1 0.1 1.0 0.8 0.4 0.2 0.2 0.1 0.0 3.4 0.6 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.1 0.2 9.0 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.4 0.0 0.0 0.0 49.7 6.5 13.0 6.4 10.0 12.6 11.3 7.3 7.3 7.2 10.4 9.6 9.7 18.2 19.6 19.5 11.0 10.3 6.2 0.3 0.2 1.2 0.3 0.2 0.2 0.3 0.2 0.3 0.1 0.2 0.4 0.6 0.0 0.0 0.0 3.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.3 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.5 0.1 0.1 0.1 0.0 0.5 0.0 0.3 0.1 0.1 1.5 0.0 0.0 0.3 0.1 0.1 0.0 0.1 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.9;salivary gland: 122.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 125.0;Alveolar cells type 2: 389.7;Gastric mucus-secreting cells: 251.8;granulocytes: 187.3;Intestinal goblet cells: 189.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 142.9;MCF7: 255.4;SK-BR-3: 234.5;SK-MEL-30: 182.2;U-87 MG: 236.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" 13.2 1.4 0.6 2.4 0.7 0.1 56.9 0.7 1.6 69.3 1.3 20.4 8.8 18.1 8.9 6.4 18.0 31.0 69.2 1.1 0.7 4.3 39.0 62.7 0.6 1.1 1.0 11.8 16.1 9.0 2.1 1.9 0.8 135.9 21.7 0.3 122.0 13.0 6.6 11.6 15.2 2.8 0.6 0.2 98.1 2.5 0.8 0.9 39.9 2.5 1.2 22.1 21.9 0.9 0.3 133.7 0.3 0.3 58.5 39.5 0.4 26.8 31.5 14.7 18.5 1.1 101.1 0.2 0.1 49.6 51.0 0.3 0.1 0.9 13.0 0.1 0.3 0.1 0.1 0.0 23.3 0.1 0.7 48.1 14.7 43.4 56.2 75.6 0.1 0.0 0.1 0.3 142.9 255.4 0.4 0.6 0.4 105.4 77.1 0.5 0.1 0.2 0.5 3.2 1.5 0.2 0.1 234.5 182.2 0.7 61.5 1.7 26.8 80.1 2.3 0.9 38.0 0.2 0.2 0.2 236.0 0.1 63.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 1.6 1.1 0.7 1.1 1.0 0.8 0.6 0.8 0.9 12.3 125.0 389.7 0.0 0.8 4.1 17.3 6.0 0.0 0.0 95.6 59.7 63.2 52.9 64.2 12.9 0.0 0.4 0.7 34.9 1.9 12.0 0.2 9.5 10.1 10.1 14.4 0.0 0.2 41.3 0.3 4.5 251.8 17.5 187.3 0.2 1.4 28.8 1.2 0.0 0.1 189.0 32.6 0.8 2.9 0.7 8.4 7.4 30.2 5.6 0.6 0.0 0.0 0.0 0.0 58.1 22.4 3.0 0.8 54.4 9.1 0.6 48.5 0.0 0.0 3.1 3.7 0.3 0.6 1.2 2.4 0.7 6.1 0.4 30.5 38.6 MLX "bHLHd13, MAD7, MXD7, TCFL4" ENSG00000108788 "MAX dimerization protein MLX" Q9UH92 17 42567072-42573239 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025329, HPA052766, HPA064438" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear membrane, Cytosol" "CAB025329: , HPA052766: AB_2681940, HPA064438: AB_2685265" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.21e-3)" "unprognostic (3.88e-1)" "unprognostic (2.46e-2)" "unprognostic (8.55e-3)" "unprognostic (2.49e-1)" "unprognostic (4.87e-2)" "unprognostic (8.66e-2)" "unprognostic (9.66e-2)" "unprognostic (2.89e-1)" "unprognostic (1.61e-2)" "unprognostic (7.43e-2)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (3.25e-1)" 31.3 28.0 15.8 21.7 16.4 16.4 26.2 16.6 18.0 19.3 19.1 38.5 47.5 15.7 16.6 29.1 17.2 20.3 55.5 16.2 16.9 28.7 51.5 27.9 27.5 16.9 15.9 14.8 32.7 19.6 18.8 21.5 16.8 18.2 38.8 9.3 24.7 18.1 74.4 25.6 42.2 20.3 16.7 24.1 35.4 8.1 16.8 30.1 24.8 86.4 29.4 27.9 20.8 17.2 36.8 41.5 32.1 33.1 48.0 55.3 22.0 53.5 47.5 57.1 51.4 38.0 37.5 43.6 36.8 46.4 51.6 54.4 59.4 34.8 50.0 35.2 55.5 45.4 27.2 43.1 56.3 61.6 63.4 47.9 38.4 45.6 41.8 38.9 42.9 52.2 50.7 38.3 66.2 49.3 87.0 31.3 22.9 90.9 37.3 39.2 66.1 47.5 46.8 44.7 49.9 24.6 23.9 31.2 61.8 42.5 63.3 72.1 30.2 50.7 32.5 55.7 80.8 38.7 47.2 41.2 56.5 39.2 60.8 43.3 64.0 91.4 34.2 80.1 37.6 35.2 35.0 34.6 66.5 30.2 30.5 31.1 82.7 33.7 90.9 35.7 48.0 68.3 15.8 16.4 16.6 18.0 16.2 16.9 16.9 15.9 16.8 16.7 16.8 17.2 31.6 67.3 69.8 9.4 35.6 41.9 28.1 41.5 33.0 29.4 39.8 30.4 24.1 40.0 47.2 27.6 25.0 37.8 35.8 97.7 60.7 48.9 19.1 30.5 29.1 28.2 25.8 42.7 8.0 68.9 49.5 26.0 55.5 26.3 46.7 18.7 27.8 49.7 68.6 25.2 8.1 46.9 30.5 63.4 62.3 24.5 35.1 59.5 32.0 7.5 58.3 13.1 51.5 5.5 7.1 77.5 86.4 31.2 61.8 24.4 132.3 62.1 30.4 31.7 52.6 22.9 31.4 9.3 41.2 45.2 49.9 44.1 38.3 48.0 54.2 36.4 MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 244.0;Pancreatic endocrine cells: 144.7;Syncytiotrophoblasts: 122.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 923.8;HHSteC: 794.2;HSkMC: 887.0;hTERT-RPE1: 925.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" 151.5 31.7 5.6 59.9 5.0 1.6 101.5 5.7 7.5 181.3 61.8 77.2 39.5 167.3 19.0 92.1 82.1 148.2 41.3 6.6 7.2 35.9 13.2 91.8 24.8 11.9 8.4 90.2 36.0 65.3 14.2 118.9 9.2 59.9 36.6 9.6 78.1 45.5 18.8 127.5 69.4 106.0 7.3 30.8 57.7 11.7 13.2 13.0 50.0 16.1 30.8 103.9 111.1 10.6 90.6 1.2 26.3 2.0 923.8 651.6 455.9 270.1 606.4 93.3 158.5 21.3 337.4 0.9 146.4 301.9 24.6 216.3 0.3 262.2 99.7 1.1 0.6 37.2 1.7 5.0 794.2 0.4 1.3 887.0 148.7 334.7 288.3 925.5 492.9 0.6 0.8 2.1 185.1 0.7 0.4 79.4 14.7 17.7 52.4 2.1 96.0 0.2 61.4 148.1 0.3 0.6 187.3 0.3 574.2 104.4 1.0 79.5 436.8 724.9 53.7 198.2 329.6 0.8 1.6 1.1 410.9 0.6 396.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 5.0 5.7 7.5 6.6 7.2 11.9 8.4 9.2 7.3 13.2 10.6 13.9 12.8 3.0 2.0 3.4 34.0 23.4 105.4 39.3 0.0 14.1 17.5 4.7 50.1 42.2 7.3 0.0 105.6 0.3 19.9 11.7 63.0 0.4 16.1 81.6 35.2 7.8 0.0 0.0 28.7 244.0 84.0 25.5 14.8 3.8 9.3 32.9 2.7 89.5 0.0 0.0 24.5 34.6 20.2 32.7 2.4 72.1 38.0 37.4 4.7 21.5 14.3 0.0 0.5 0.1 144.7 33.0 54.9 0.3 21.8 19.9 11.7 46.8 0.8 39.5 11.1 73.9 0.8 0.8 33.7 34.2 122.7 2.5 15.6 18.6 37.9 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP23B "MIFR, MIFR-1, MMP22" ENSG00000189409 "Matrix metallopeptidase 23B" O75900 1 1632163-1635263 "Enzymes, Predicted intracellular proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 29.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 90.5;Leydig cells: 98.2;NK-cells: 64.9;Peritubular cells: 177.9" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 11.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 11.3" "Cell line enhanced" "Detected in some" "HHSteC: 4.4;NTERA-2: 2.7;PC-3: 1.9;U-266/70: 3.9" "Region enriched" "Detected in some" 5 "cerebellum: 7.8" "Low region specificity" "Detected in some" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (2.19e-2)" "unprognostic (6.31e-2)" "unprognostic (6.70e-3)" "unprognostic (1.29e-1)" "unprognostic (3.99e-2)" "unprognostic (9.31e-2)" "unprognostic (6.94e-2)" "unprognostic (1.20e-1)" "unprognostic (8.06e-2)" "unprognostic (8.37e-2)" "unprognostic (2.22e-1)" "unprognostic (2.33e-1)" "unprognostic (2.26e-11)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.44e-2)" "unprognostic (6.66e-2)" 7.1 2.8 0.4 0.3 0.5 1.3 4.1 0.1 1.0 16.7 0.0 5.0 1.9 15.4 0.0 2.8 11.0 2.9 15.0 0.3 0.0 3.2 3.3 14.3 1.1 0.4 0.0 29.9 1.6 0.0 5.7 2.8 0.1 11.8 0.1 0.1 1.0 1.1 0.5 3.1 3.4 1.2 0.0 3.0 4.3 5.2 0.1 0.0 2.4 0.0 0.1 11.9 10.9 0.2 0.6 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.4 0.5 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.5 0.2 1.2 4.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.4 0.0 0.2 2.7 0.0 1.9 0.9 0.0 1.1 0.0 0.0 0.4 0.2 0.3 0.0 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.3 0.0 3.9 0.2 1.1 0.0 0.2 0.1 0.0 0.2 0.0 1.5 0.0 0.9 0.0 0.3 1.0 0.0 0.1 0.0 0.7 0.1 2.2 0.1 11.3 0.3 1.7 0.4 0.5 0.1 1.0 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.2 2.2 0.0 0.5 1.0 1.1 13.4 0.8 0.7 0.6 1.3 1.7 1.5 9.6 1.5 0.4 1.8 0.0 4.0 27.4 3.0 0.0 1.2 1.0 4.0 3.5 2.2 3.0 2.7 0.3 0.5 2.2 90.5 4.6 1.0 0.0 1.4 12.1 1.0 5.7 3.3 0.6 1.9 4.1 1.0 18.5 6.2 98.2 1.3 19.6 0.0 1.2 0.5 64.9 0.0 0.2 4.3 0.9 177.9 4.3 0.5 2.7 1.0 0.5 7.7 0.0 0.7 5.3 2.1 10.5 0.7 15.8 10.3 8.1 2.1 1.7 0.9 MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Basal respiratory cells: 56.8;Distal enterocytes: 82.0;Paneth cells: 46.2;Proximal enterocytes: 47.2;Urothelial cells: 43.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.8;HaCaT: 86.9;hTCEpi: 38.3;OE19: 41.7;RT4: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057288, HPA057890" Approved "Nucleoplasm,Focal adhesion sites" "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Focal adhesion sites" "HPA057288: , HPA057890: " "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" 14.7 2.0 18.7 0.5 18.1 0.2 8.3 12.1 18.8 4.1 11.9 17.5 1.8 5.2 2.1 13.5 6.1 1.4 3.8 16.2 15.6 1.9 0.3 14.1 0.2 15.2 17.8 1.1 0.8 0.1 1.3 2.0 12.9 5.0 10.5 3.0 2.5 3.5 1.8 23.7 10.2 4.1 14.4 1.1 8.8 22.3 19.3 0.3 5.9 2.4 3.2 16.3 7.6 13.9 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.1 1.5 0.0 0.1 86.9 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.0 4.3 0.0 0.0 1.2 38.3 0.0 3.1 0.7 0.3 0.3 0.0 0.2 0.0 0.3 0.1 0.3 0.0 41.7 0.1 0.8 0.0 0.0 0.0 15.7 0.2 0.7 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.1 0.6 0.2 1.0 0.0 0.4 6.3 3.7 0.0 0.9 0.2 0.9 0.0 0.4 18.7 18.1 12.1 18.8 16.2 15.6 15.2 17.8 12.9 14.4 19.3 13.9 31.5 28.9 26.5 47.7 0.4 38.5 5.3 56.8 21.1 2.7 1.0 1.5 1.3 7.2 15.2 7.3 0.0 0.0 0.2 82.0 0.0 1.2 6.7 0.1 0.0 16.8 3.6 0.4 2.8 0.4 0.0 4.4 12.2 0.1 0.0 0.0 17.9 0.0 0.1 1.7 4.8 32.9 2.0 0.0 1.8 13.4 1.2 0.5 3.6 10.3 0.4 9.4 1.0 1.0 0.6 16.7 46.2 3.0 0.1 8.6 47.2 0.8 4.5 0.5 6.6 0.7 5.5 1.1 3.7 34.9 33.1 0.0 1.0 0.1 21.5 43.9 MPHOSPH6 MPP6 ENSG00000135698 "M-phase phosphoprotein 6" Q99547 16 82147798-82170224 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003674, HPA026948" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli" "CAB003674: , HPA026948: AB_1854077" "unprognostic (2.58e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-1)" "unprognostic (2.97e-3)" "prognostic unfavorable (4.36e-5)" "unprognostic (2.00e-2)" "unprognostic (2.29e-3)" "prognostic favorable (3.41e-5)" "unprognostic (7.52e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "unprognostic (9.43e-2)" 19.8 21.3 26.7 25.5 26.8 20.0 72.5 29.6 32.8 23.6 19.1 22.7 13.8 25.8 22.4 36.2 15.9 16.5 13.9 26.7 28.3 17.8 15.9 18.7 24.7 22.1 24.7 13.4 9.0 16.2 21.3 24.4 23.1 15.3 24.9 31.6 26.0 13.0 18.0 40.1 15.9 22.8 21.7 16.7 15.7 14.1 27.5 20.7 11.6 17.5 26.2 34.7 21.0 28.4 67.8 36.2 79.0 38.9 37.7 52.7 43.5 71.1 84.7 60.6 29.3 58.5 38.4 55.2 42.0 39.2 44.7 69.2 76.2 73.6 80.8 41.3 49.9 44.5 31.2 106.5 37.5 111.9 65.9 33.6 64.7 36.2 102.8 30.5 70.6 75.7 106.2 15.3 93.4 54.8 86.5 131.2 72.4 83.4 49.5 105.5 36.6 36.5 55.3 69.8 54.1 23.3 119.6 52.5 53.6 32.4 92.2 68.6 56.0 56.5 56.3 50.2 51.3 22.4 58.0 217.9 51.0 89.9 73.2 26.1 38.3 36.9 38.2 46.5 48.5 35.6 38.7 39.9 44.9 29.2 41.1 38.8 4.9 33.1 33.8 27.2 44.3 28.3 26.7 26.8 29.6 32.8 26.7 28.3 22.1 24.7 23.1 21.7 27.5 28.4 13.2 19.2 38.3 20.5 22.9 38.7 40.3 123.9 19.4 14.5 74.3 50.0 31.5 14.3 66.2 20.2 10.4 56.9 23.0 21.7 50.9 45.2 6.5 13.9 18.5 19.3 9.0 23.1 38.5 28.1 46.1 31.4 15.8 22.0 18.3 21.9 20.0 19.0 49.6 20.2 35.6 20.7 40.7 29.1 42.7 7.5 11.1 55.9 32.0 12.2 56.0 61.1 34.0 29.7 17.1 56.4 28.4 10.1 22.3 38.6 12.2 46.5 32.7 24.5 19.7 15.4 30.1 36.9 57.5 30.6 54.0 32.8 27.4 26.3 34.0 48.1 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261940 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 58.8" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" 9.2 17.0 7.3 6.3 6.9 18.0 11.0 5.4 15.5 10.5 6.4 16.2 13.3 9.1 5.3 17.0 11.0 3.6 14.0 7.5 2.7 17.2 11.7 17.0 7.0 11.8 4.2 7.7 26.7 5.6 22.3 5.5 10.9 17.2 3.4 0.9 17.3 5.7 5.2 17.8 17.6 2.1 1.1 21.7 18.9 13.0 4.9 4.2 58.8 2.1 3.7 12.9 12.6 3.8 17.0 6.9 0.9 6.5 3.1 3.3 29.3 7.3 5.1 4.0 5.5 11.6 29.7 8.9 10.5 4.2 9.8 15.9 1.0 11.2 1.8 5.1 9.5 10.8 22.1 10.7 7.8 4.8 11.0 6.1 11.4 6.4 9.2 4.7 5.8 7.2 4.5 3.9 4.5 36.3 8.4 10.2 2.5 11.6 32.0 10.8 2.2 9.3 5.9 33.0 7.4 6.4 18.3 17.5 5.4 2.5 12.8 6.7 14.6 8.1 15.2 16.6 6.1 6.8 3.6 9.5 16.0 14.3 4.9 4.8 5.7 1.5 1.8 7.5 1.3 0.9 1.5 1.8 4.3 1.5 1.4 1.0 1.1 0.8 6.8 1.3 4.6 2.2 7.3 6.9 5.4 15.5 7.5 2.7 11.8 4.2 10.9 1.1 4.9 3.8 5.2 9.6 26.3 33.0 6.5 6.2 8.5 9.2 6.8 36.4 12.6 9.5 12.4 5.7 16.6 5.5 12.5 31.3 7.0 39.8 3.9 12.2 5.1 17.8 6.7 7.8 23.4 1.7 56.7 16.6 19.2 6.4 63.7 25.2 14.5 14.3 3.9 7.0 19.7 37.0 61.2 24.8 18.3 11.9 11.4 12.2 3.1 14.5 1.8 13.1 11.4 5.7 7.2 14.6 7.9 18.6 17.5 2.6 9.7 17.6 30.7 5.8 18.8 3.5 6.6 7.2 6.7 19.1 26.2 9.7 5.8 50.1 9.1 7.8 22.3 14.8 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 MRPS11 "FLJ22512, FLJ23406, HCC-2" ENSG00000181991 "Mitochondrial ribosomal protein S11" P82912 15 88467453-88480776 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043752, HPA050345" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA043752: AB_2678653, HPA050345: AB_2681100" "unprognostic (2.66e-1)" "prognostic favorable (3.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (3.21e-1)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "unprognostic (6.45e-2)" "prognostic favorable (4.75e-4)" "unprognostic (8.31e-2)" "unprognostic (3.37e-1)" "unprognostic (1.83e-1)" "unprognostic (9.44e-2)" "unprognostic (7.26e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" 9.4 16.9 12.0 4.0 12.1 2.8 8.6 12.8 18.3 5.3 11.4 9.3 7.9 5.3 3.8 10.9 4.8 4.5 26.1 12.5 12.1 14.0 20.5 5.2 5.6 12.7 12.3 3.5 10.5 3.8 7.6 2.3 12.9 7.4 3.5 2.5 6.0 3.4 24.7 7.2 7.4 4.3 11.7 8.0 9.6 9.0 12.7 5.1 9.6 15.0 4.4 8.4 5.6 12.1 10.5 41.1 6.1 10.4 13.8 6.6 16.1 8.3 14.6 10.7 11.5 28.9 16.0 9.7 17.0 7.1 11.3 14.8 17.9 11.5 5.5 12.8 43.8 13.2 23.1 32.0 16.5 4.5 8.3 13.4 11.1 9.2 9.2 5.8 14.3 12.3 9.6 4.3 18.1 45.1 9.3 19.0 16.3 13.4 43.8 19.0 11.6 23.0 15.5 28.4 19.3 9.6 8.6 21.6 33.6 5.3 19.8 24.7 6.8 15.2 16.8 9.9 12.5 8.5 16.5 11.7 18.3 11.2 16.3 31.1 25.1 19.3 15.1 27.6 17.6 27.5 17.2 17.8 29.5 18.2 18.1 17.6 9.5 30.1 17.8 31.9 35.1 26.0 12.0 12.1 12.8 18.3 12.5 12.1 12.7 12.3 12.9 11.7 12.7 12.1 42.1 6.4 20.4 10.4 30.4 22.8 27.5 69.2 31.9 36.9 38.1 47.2 6.3 35.8 39.6 46.0 47.9 91.0 34.6 85.5 135.0 63.9 30.2 27.1 37.8 34.2 24.7 40.6 14.0 66.8 89.7 32.7 25.0 32.5 33.6 40.4 44.6 92.6 90.5 26.9 15.0 60.3 50.8 33.1 24.5 34.2 33.2 31.0 32.0 8.4 65.0 44.4 72.1 16.6 16.8 67.0 70.7 42.5 36.5 32.2 90.8 145.3 29.7 45.1 19.7 29.7 51.8 90.3 42.0 49.1 28.3 89.6 32.3 96.0 64.6 34.5 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 2801.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.6" "Lineage enhanced" "Detected in many" "granulocytes: 41.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 126.1;hTERT-RPE1: 110.6;U-937: 106.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 32: U-937 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" 44.9 10.7 12.9 20.9 13.6 21.2 26.3 12.5 12.8 29.5 18.8 108.0 11.9 85.8 20.1 63.0 41.4 33.2 90.8 11.9 18.3 10.1 3.8 30.6 5.7 15.9 15.2 16.9 5.8 3.2 6.8 25.2 13.8 52.7 27.8 12.5 10.8 103.0 104.0 9.7 25.6 123.9 14.6 13.6 36.2 5.8 18.2 4.1 14.5 69.2 3.9 60.9 23.7 11.8 8.8 19.2 16.4 75.9 71.6 63.0 0.5 87.0 92.9 33.2 19.8 0.7 1.0 0.0 18.3 126.1 10.5 1.9 7.7 22.1 30.0 0.2 15.9 0.0 16.7 0.9 46.6 47.1 0.3 33.4 11.9 28.1 39.0 110.6 68.2 0.1 0.3 0.3 76.8 2.9 0.0 11.0 5.4 0.2 10.4 0.2 22.0 0.5 7.5 1.0 0.4 7.9 30.0 1.8 21.9 16.8 14.1 44.5 78.9 42.3 22.8 19.5 34.2 8.0 6.7 0.2 11.5 106.7 26.9 15.0 0.6 41.6 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 6.8 8.3 0.4 10.8 0.1 1.4 12.9 13.6 12.5 12.8 11.9 18.3 15.9 15.2 13.8 14.6 18.2 11.8 55.3 12.8 3.4 76.7 0.8 6.4 16.4 11.4 4.0 22.7 2.2 45.3 2801.7 4.3 1.2 3.7 0.0 0.4 8.3 0.0 0.0 9.3 5.7 0.9 16.7 154.2 0.0 17.4 37.1 1.0 0.4 108.8 1.1 0.4 2.5 7.4 28.2 0.2 0.5 21.9 56.6 0.0 0.0 0.0 13.7 2.2 12.5 4.0 10.6 62.8 1.6 44.4 2.1 37.7 1.4 1.6 0.0 116.6 0.3 14.8 0.0 0.4 6.8 10.6 105.2 37.7 218.7 4.2 4.7 0.8 4.5 0.7 2.4 10.3 0.0 2.9 MSX2 "CRS2, FPP, HOX8, MSH, PFM, PFM1" ENSG00000120149 "Msh homeobox 2" P35548 5 174724582-174730896 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Osteogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 25.8;placenta: 33.6;urinary bladder: 17.5" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 162.6;Endometrial ciliated cells: 65.7;Glandular and luminal cells: 62.2;Syncytiotrophoblasts: 233.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 18.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 322.0" "Region enriched" "Detected in some" 5 "cerebellum: 6.2" "Low region specificity" "Detected in many" HPA005652 Uncertain Supported "Nuclear speckles" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear speckles" "HPA005652: AB_1079418" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-4)" "unprognostic (7.64e-3)" "unprognostic (5.06e-2)" "unprognostic (2.12e-6)" "unprognostic (1.43e-2)" 2.1 0.3 0.7 0.5 1.0 0.0 8.1 4.3 1.1 2.7 1.1 0.9 0.3 6.8 0.0 0.6 0.9 0.9 1.6 1.2 1.4 0.3 0.0 0.8 0.1 7.8 1.3 0.2 0.4 25.8 0.3 33.6 4.1 2.5 0.1 0.0 0.8 0.8 1.9 6.9 0.8 1.4 5.4 0.8 2.8 5.6 1.3 0.1 0.7 1.8 0.1 17.5 1.8 5.4 0.4 4.0 1.1 3.2 0.0 0.0 322.0 2.2 3.6 0.7 0.1 56.6 23.0 0.0 8.6 0.2 19.6 6.2 17.6 6.4 0.2 0.0 10.7 0.0 1.4 0.0 2.4 0.0 3.0 3.7 4.5 3.1 3.5 0.0 0.0 0.0 0.0 0.0 5.0 27.7 0.0 0.4 2.5 38.3 8.5 0.0 8.8 0.1 4.0 35.3 0.0 2.5 0.0 43.0 2.9 69.6 25.7 0.2 0.0 1.1 5.5 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 4.3 1.1 1.2 1.4 7.8 1.3 4.1 5.4 1.3 5.4 1.5 0.0 0.0 2.3 0.0 9.6 2.4 0.1 3.4 0.2 15.8 18.9 1.7 0.0 0.1 0.0 0.0 162.6 0.2 0.3 0.0 0.6 0.2 65.7 4.9 0.7 0.0 0.0 0.0 0.0 13.9 5.3 5.1 62.2 4.5 0.1 0.4 0.0 11.3 0.0 0.0 1.9 0.0 0.6 2.9 0.6 0.0 1.0 1.8 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.1 2.3 1.9 0.1 0.1 0.0 0.0 8.9 4.8 1.4 4.5 2.0 11.4 233.8 1.0 0.6 1.2 9.8 MT-CO2 "CO2, COX2, MTCO2" ENSG00000198712 "Mitochondrially encoded cytochrome c oxidase II" P00403 MT 7586-8269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 164780.5;heart muscle: 210840.8" "Cell type enriched" "Detected in many" 13 "Cardiomyocytes: 709929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HeLa: 73985.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016243, HPA051505, HPA054758" Enhanced NA NA 240000 "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB016243: AB_2066366, HPA051505: AB_2681511, HPA054758: AB_2682595" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (4.57e-2)" "unprognostic (5.31e-2)" "unprognostic (2.77e-2)" "unprognostic (1.96e-2)" "prognostic favorable (2.89e-4)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (2.72e-3)" "prognostic favorable (7.10e-4)" "unprognostic (1.25e-1)" "unprognostic (9.30e-2)" "unprognostic (3.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.50e-2)" "unprognostic (3.72e-3)" 27287.7 50118.4 114427.0 5960.9 114629.6 9211.1 23112.5 102567.5 164780.5 8637.9 123709.0 47542.8 18239.3 10045.0 10813.1 24529.5 11015.1 5914.4 210840.8 108795.0 110116.5 112074.1 105449.6 14032.6 6314.3 129884.9 115346.3 7950.6 24515.9 29782.0 16861.9 10397.8 125082.8 25688.4 24989.1 8983.3 21379.6 12907.0 93258.6 22997.0 36121.9 9693.6 102620.8 18194.3 45409.4 14516.5 123032.8 6034.4 16877.7 109930.2 7889.2 21068.8 13184.5 102646.5 6276.2 9796.4 12777.6 12396.3 25548.5 9745.3 9393.2 7927.6 6429.8 4420.4 6584.3 10616.0 13681.5 12924.1 6467.6 11751.8 4522.1 23074.6 1724.1 16319.1 5925.8 10089.3 8726.0 9297.7 73985.8 20756.8 5543.0 7919.2 9987.0 14433.8 23568.7 2276.3 8072.8 14337.8 4979.3 12668.7 8862.9 12216.0 12212.6 13490.3 5804.8 22519.7 3353.4 12256.7 6160.6 5998.2 3899.6 10866.7 17578.2 17096.2 4758.2 7830.6 6527.3 15842.4 11881.3 18742.2 11084.6 31596.4 12345.0 10576.0 9043.3 10116.0 5740.6 6151.2 6563.0 7590.8 5638.0 15586.1 7129.7 20953.0 13541.7 15753.7 5586.8 8887.6 6782.0 11844.8 6189.5 6338.9 6316.7 10947.0 6386.1 7947.1 5329.9 6846.5 10055.3 8426.1 5367.4 7670.7 114427.0 114629.6 102567.5 164780.5 108795.0 110116.5 129884.9 115346.3 125082.8 102620.8 123032.8 102646.5 4337.7 1445.5 1999.8 0.0 11825.3 6754.0 8961.4 22171.6 22140.9 0.0 11994.6 16742.4 709929.9 18464.2 10323.3 18597.6 0.0 0.0 7569.1 29582.2 3709.5 3684.4 1119.7 12108.5 6979.9 16215.0 6396.9 27238.9 0.0 4873.7 0.0 10942.5 19089.4 20683.3 2144.6 17185.5 15141.7 53416.5 0.0 0.0 0.0 17158.1 14290.0 26774.7 4814.0 5284.9 7663.3 9292.7 5140.4 0.0 7967.0 0.0 6828.1 0.0 0.0 4709.1 15133.6 5123.0 14109.6 5949.4 40280.5 22569.2 7617.1 0.0 7060.4 9361.8 14171.2 7120.5 8965.1 26952.2 6702.8 0.0 8863.0 13639.8 19371.4 14261.8 MT1A "MT1, MT1S" ENSG00000205362 "Metallothionein 1A" P04731 16 56638666-56640087 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 488.0;liver: 430.8" "Group enriched" "Detected in many" 6 "Adipocytes: 797.9;Fibroblasts: 244.1;Hepatocytes: 343.8;Skeletal myocytes: 561.9;Smooth muscle cells: 889.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 18.4;ASC TERT1: 27.9;HHSteC: 19.7;HMC-1: 29.5;hTEC/SVTERT24-B: 80.2;NTERA-2: 40.1" "Low region specificity" "Detected in single" "CAB002161, CAB013056" Approved NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 5: NTERA-2 - Transcription" "Cluster 48: Smooth muscle cells - ECM organization" "CAB002161: AB_563878, CAB013056: " "unprognostic (1.36e-1)" "unprognostic (4.91e-3)" "unprognostic (1.22e-1)" "unprognostic (3.30e-1)" "unprognostic (1.26e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-2)" "unprognostic (6.67e-3)" "unprognostic (3.10e-2)" "unprognostic (1.86e-1)" "unprognostic (9.43e-2)" "unprognostic (1.35e-2)" 488.0 64.3 9.8 10.8 12.3 0.0 208.1 9.8 14.1 62.0 8.2 28.9 7.7 13.6 1.3 33.4 68.7 30.2 63.3 9.3 10.7 136.8 430.8 115.2 0.6 10.6 10.8 19.8 90.3 2.1 25.9 0.7 11.7 33.1 13.1 4.4 18.9 2.9 100.0 26.1 23.4 16.9 11.5 3.4 42.9 8.4 10.8 6.1 67.7 6.1 0.7 34.0 22.6 9.7 0.0 6.2 0.0 0.1 18.4 27.9 0.4 1.9 7.9 1.2 1.5 2.3 4.8 0.0 2.4 1.1 0.0 0.5 0.0 0.4 2.9 0.0 0.0 0.0 2.5 9.9 19.7 0.2 29.5 8.2 0.0 80.2 0.0 0.0 7.7 0.0 0.7 0.0 5.5 0.0 0.0 0.1 40.1 0.0 0.0 0.0 0.0 3.6 0.5 0.0 0.3 0.1 0.0 0.3 0.0 0.9 0.0 0.3 6.3 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 9.8 12.3 9.8 14.1 9.3 10.7 10.6 10.8 11.7 11.5 10.8 9.7 797.9 9.6 1.7 0.7 1.8 27.4 11.3 1.9 5.7 0.0 11.7 15.4 5.4 8.6 5.1 0.0 0.0 1.1 1.0 11.1 13.7 2.7 0.1 11.9 6.9 63.2 3.6 29.5 0.0 1.8 12.8 244.1 5.1 23.8 3.8 0.3 15.7 343.8 0.3 0.0 0.0 32.3 0.0 10.4 39.6 0.7 55.0 12.4 33.8 0.0 0.0 0.0 0.0 0.0 0.0 3.0 18.6 12.8 1.2 27.9 86.5 16.1 3.0 0.0 26.3 561.9 889.5 0.0 0.3 2.1 19.5 0.5 6.6 0.4 34.7 13.7 MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "heart muscle: 50.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 548.4;Inhibitory neurons: 671.8" "Cancer enhanced" "Detected in some" "urothelial cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 13.2;HeLa: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge" "HPA031473: AB_2673901, HPA031474: AB_10600109, HPA031475: AB_10600442" "unprognostic (1.67e-1)" "unprognostic (3.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (1.30e-3)" "unprognostic (3.45e-2)" "unprognostic (3.91e-5)" "unprognostic (2.51e-2)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (9.62e-2)" 0.2 0.2 0.4 0.1 1.7 0.1 0.1 1.2 9.7 0.6 1.8 0.9 0.1 1.5 0.0 0.3 0.8 0.1 50.2 1.0 0.0 0.1 0.9 0.1 0.6 0.0 0.1 7.5 4.8 0.0 6.1 0.0 0.0 0.3 0.2 4.6 1.0 0.1 0.1 0.2 0.4 1.2 2.2 0.5 1.3 1.2 1.0 0.2 0.5 0.1 0.1 1.3 0.2 2.4 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.2 13.2 0.4 0.0 0.0 0.0 0.5 0.0 5.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 2.3 1.6 0.1 0.4 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.7 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.7 1.2 9.7 1.0 0.0 0.0 0.1 0.0 2.2 1.0 2.4 0.1 0.0 0.5 10.4 0.1 0.5 0.7 0.1 0.0 0.0 0.3 0.4 145.8 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.3 1.0 0.7 0.0 0.8 548.4 0.6 0.0 5.9 0.0 1.1 0.0 1.2 0.4 0.5 0.1 0.0 671.8 0.7 0.0 0.0 0.8 3.3 0.9 0.2 1.8 15.0 0.1 0.0 0.0 18.1 16.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 3.6 0.0 0.0 1.6 1.0 0.1 4.1 1.8 0.1 0.3 0.3 19.6 0.0 1.1 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 588.9" "Cell type enriched" "Detected in many" 7 "Cardiomyocytes: 481.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 137.3;hTERT-HME1: 24.0;HUVEC TERT2: 28.3;OE19: 47.5;RT4: 25.1;TIME: 33.1" HPA039827 Approved NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" 65.3 54.7 2.0 2.6 2.4 4.0 22.3 6.3 1.8 17.3 1.3 18.1 16.8 29.4 1.8 41.4 4.7 4.8 588.9 1.8 2.5 5.7 2.4 31.8 6.0 6.7 2.8 5.1 35.1 0.6 1.7 56.6 7.7 19.8 11.8 1.3 18.3 38.2 11.6 9.6 15.4 17.2 1.6 12.4 23.4 2.5 3.5 1.4 3.7 15.5 8.6 84.1 26.9 1.7 6.0 1.7 0.0 10.5 2.3 0.1 3.2 0.9 8.6 1.4 1.7 7.3 4.1 0.1 0.7 0.0 8.9 2.6 0.0 4.4 1.7 0.0 0.2 137.3 1.7 0.1 0.4 0.0 0.1 0.0 3.1 0.3 24.0 0.1 28.3 0.2 1.9 0.0 0.7 2.3 0.0 0.1 0.1 47.5 2.4 0.0 11.4 0.3 0.0 25.1 0.0 4.1 0.6 5.9 0.0 1.2 7.9 0.1 33.1 0.1 2.6 0.4 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.4 0.0 0.0 3.4 2.0 0.0 0.5 0.0 0.8 0.0 0.2 2.4 2.0 2.4 6.3 1.8 1.8 2.5 6.7 2.8 7.7 1.6 3.5 1.7 22.9 9.6 0.6 0.0 0.3 0.0 10.2 0.0 0.0 0.3 3.0 1.0 481.4 5.7 0.6 25.8 0.0 4.4 0.0 26.9 7.9 32.5 0.1 1.1 3.0 15.1 1.8 1.3 0.0 18.9 2.4 9.8 7.1 3.5 0.0 65.1 4.6 0.2 1.4 0.0 0.0 7.9 0.0 7.9 0.0 0.7 4.7 8.7 0.0 0.0 3.4 0.6 0.0 0.0 0.0 21.5 24.9 17.0 0.0 11.0 18.1 0.3 0.7 0.2 0.0 0.2 8.1 0.0 1.6 0.0 0.0 1.2 0.2 13.2 6.6 22.4 NAPA ENSG00000105402 "NSF attachment protein alpha" P54920 19 47487637-47515091 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010100, HPA046149, HPA050196" Approved Uncertain Cytosol NA NA 2200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "CAB010100: AB_628263, HPA046149: AB_2679557, HPA050196: AB_2681048" "unprognostic (9.83e-2)" "unprognostic (9.43e-3)" "unprognostic (1.12e-2)" "unprognostic (1.76e-3)" "unprognostic (9.72e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (5.61e-2)" "unprognostic (2.42e-3)" "unprognostic (1.09e-3)" "prognostic favorable (4.26e-9)" "unprognostic (4.04e-2)" "unprognostic (4.17e-2)" "unprognostic (8.55e-2)" "unprognostic (2.90e-2)" 83.0 147.5 104.8 56.8 112.1 115.2 83.6 112.4 146.1 87.2 89.8 79.5 61.9 102.0 54.5 122.7 86.0 63.7 112.9 125.1 102.5 98.6 153.2 79.8 57.0 120.9 99.8 66.4 92.0 101.1 96.5 56.9 119.3 105.1 50.8 83.7 124.3 94.6 180.2 131.9 62.4 72.6 97.3 66.4 83.6 79.3 111.2 85.2 74.6 116.8 53.1 76.7 85.7 112.8 73.1 99.3 48.1 85.3 100.4 80.9 36.7 78.1 98.7 189.3 229.1 76.1 44.3 55.8 41.5 110.4 119.1 56.3 77.7 98.1 72.8 89.2 84.6 70.1 88.5 93.6 256.9 80.6 124.5 122.0 70.2 77.0 47.6 38.1 92.1 74.9 67.0 150.0 123.7 66.2 115.7 284.6 40.5 110.7 75.7 79.8 42.2 82.6 149.6 133.5 174.9 67.6 101.0 126.4 76.6 43.8 98.9 136.9 91.0 97.4 51.3 83.9 93.6 94.5 143.7 76.9 176.3 89.5 102.5 196.4 165.0 313.1 96.1 189.8 81.3 68.7 82.9 94.3 132.3 70.3 84.8 85.3 187.9 111.1 201.1 209.9 112.2 209.4 104.8 112.1 112.4 146.1 125.1 102.5 120.9 99.8 119.3 97.3 111.2 112.8 59.1 12.8 41.5 19.9 48.6 63.3 91.1 73.5 92.2 55.1 69.5 63.5 3.8 72.9 44.5 51.5 27.1 106.4 73.3 89.1 178.1 110.9 44.2 40.8 37.5 49.3 83.6 89.9 30.5 99.8 69.0 48.0 94.8 70.0 64.7 23.8 39.7 89.6 131.1 35.3 21.7 62.6 99.7 58.4 69.1 37.4 42.9 87.7 97.8 14.0 79.1 76.7 66.9 11.1 21.8 100.2 69.8 46.3 92.9 50.5 80.3 99.0 20.1 47.3 92.1 44.3 63.0 119.0 73.7 97.4 68.6 228.9 58.0 61.7 50.7 75.5 NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 676.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.1;Leydig cells: 386.8;Paneth cells: 313.2;Peritubular cells: 356.9;Prostatic glandular cells: 293.3;Proximal enterocytes: 413.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 431.7;HSkMC: 305.6;SK-MEL-30: 473.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" NA NA 8100000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" 166.3 27.7 116.1 61.4 115.2 5.7 183.3 90.6 156.0 676.6 125.7 259.3 195.0 253.9 48.3 206.8 281.5 202.6 119.1 147.1 117.1 67.2 5.8 312.0 57.3 101.7 140.7 635.9 27.1 48.3 125.3 21.6 117.0 376.0 109.3 14.5 65.4 113.5 26.6 199.1 314.1 113.0 95.0 25.8 139.9 44.5 109.5 25.3 85.9 28.4 22.4 246.5 373.8 97.3 138.8 42.9 7.2 38.5 431.7 222.7 19.7 195.5 238.6 64.1 64.7 11.8 242.6 0.2 122.2 245.7 44.8 153.4 40.8 180.1 19.6 132.9 23.0 6.8 40.5 72.4 69.4 0.5 3.1 305.6 162.0 94.6 57.6 19.1 48.7 8.0 1.4 0.4 20.6 20.4 0.4 11.7 2.9 142.3 65.2 6.4 0.1 4.7 122.5 16.6 3.1 102.2 31.2 1.2 473.8 7.1 160.2 24.3 68.9 62.4 49.7 180.0 30.3 0.9 1.1 0.8 45.4 0.6 19.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.8 0.4 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.1 116.1 115.2 90.6 156.0 147.1 117.1 101.7 140.7 117.0 95.0 109.5 97.3 150.4 3.2 2.3 0.0 2.9 174.6 237.3 22.6 107.0 35.5 41.5 32.8 43.5 55.8 11.9 36.8 6.2 1.0 5.1 395.1 3.9 43.0 2.0 15.6 55.7 84.3 54.5 3.4 0.0 7.7 2.6 241.4 39.8 10.1 13.4 80.9 47.8 1.5 54.6 6.7 0.0 244.6 12.2 2.2 76.6 13.1 386.8 6.6 60.5 0.0 5.8 13.4 0.0 0.0 0.0 97.5 313.2 356.9 1.1 293.3 413.8 19.7 24.5 10.2 131.5 14.0 142.9 1.4 7.6 61.4 202.4 1.4 29.6 15.1 220.4 206.5 NBPF4 FLJ32833 ENSG00000196427 "NBPF member 4" Q96M43 1 108223341-108244081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.1;intestine: 1.2;testis: 3.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.9" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.1;K-562: 10.2;Karpas-707: 3.1;MCF7: 12.6;THP-1: 3.8" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (6.33e-2)" "unprognostic (2.08e-1)" "unprognostic (2.18e-2)" "unprognostic (8.29e-2)" "unprognostic (2.90e-1)" "unprognostic (8.73e-2)" 0.0 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 3.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 10.2 3.1 0.0 12.6 0.0 0.0 0.6 0.0 0.0 0.0 1.7 0.6 0.0 0.0 0.2 0.0 0.0 0.1 1.4 0.0 0.1 3.8 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NBPF6 ENSG00000186086 "NBPF member 6" Q5VWK0 1 108450282-108471002 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 2.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.2;Microglial cells: 1.0" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.5;HeLa: 1.9;K-562: 11.6;SK-BR-3: 2.4;SK-MEL-30: 1.9" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (4.36e-2)" "unprognostic (5.87e-2)" "unprognostic (4.62e-2)" "unprognostic (2.39e-1)" "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.5 0.5 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.9 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 678.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" 62.1 81.6 87.4 33.8 93.8 26.2 56.3 63.1 100.7 54.7 70.8 40.3 49.3 45.2 135.9 30.2 46.4 45.4 55.1 94.2 96.8 94.8 120.2 49.7 39.0 70.7 73.6 61.5 64.5 152.6 51.7 45.2 77.2 67.7 38.4 164.1 99.5 63.5 45.7 26.6 47.6 40.9 75.3 56.4 50.4 40.8 90.8 41.9 103.4 40.9 34.8 48.3 31.1 73.9 53.3 35.2 61.8 83.6 128.2 72.5 41.4 56.6 59.1 48.0 54.6 39.5 87.3 4.8 115.0 62.2 66.4 51.9 39.6 59.6 56.2 61.2 48.8 69.2 30.8 28.7 55.8 38.3 23.9 55.8 55.3 33.8 43.6 68.4 55.9 54.0 23.4 83.3 60.1 27.4 42.9 12.0 33.2 52.0 33.4 16.1 34.2 122.1 119.1 56.0 65.0 67.3 61.9 91.7 88.3 46.0 64.7 37.6 64.5 58.7 22.1 48.0 56.8 53.6 65.8 22.0 62.1 24.9 45.6 70.4 32.1 26.4 22.9 39.9 29.2 12.8 40.6 28.2 37.0 10.4 80.9 63.9 19.5 23.5 40.1 11.2 50.6 62.4 87.4 93.8 63.1 100.7 94.2 96.8 70.7 73.6 77.2 75.3 90.8 73.9 100.3 57.7 62.6 74.7 76.4 111.5 176.4 133.4 82.0 196.4 134.3 68.5 70.0 143.0 101.4 154.5 141.8 146.9 94.0 98.0 140.8 207.4 20.2 69.5 91.5 103.7 137.6 184.9 189.5 145.3 263.8 164.1 62.7 118.2 60.2 365.2 116.0 169.8 154.1 318.0 184.9 81.9 177.0 205.9 154.9 15.4 116.5 137.0 170.7 69.3 176.1 300.6 87.6 114.1 125.4 179.8 100.5 156.9 107.6 262.6 198.5 173.0 67.7 322.9 131.5 74.3 149.3 26.6 33.2 71.1 101.3 191.5 156.4 678.1 83.3 256.2 NDOR1 "bA350O14.9, CIAE1, NR1" ENSG00000188566 "NADPH dependent diflavin oxidoreductase 1" Q9UHB4 9 137205685-137217009 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Oligodendrocytes: 10.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024504 Approved Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Intermediate filaments" "HPA024504: AB_1854338" "unprognostic (1.67e-1)" "unprognostic (1.44e-2)" "unprognostic (3.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (5.89e-3)" "unprognostic (5.99e-2)" "unprognostic (9.30e-2)" "unprognostic (3.00e-1)" "unprognostic (2.61e-3)" "unprognostic (1.14e-1)" "unprognostic (1.07e-1)" "unprognostic (4.69e-3)" "unprognostic (2.05e-1)" "unprognostic (4.30e-2)" "unprognostic (6.74e-3)" 6.5 8.2 8.7 9.8 9.6 17.2 6.9 7.9 12.5 8.1 5.4 8.4 9.6 7.8 2.0 8.3 7.9 4.6 6.6 8.3 7.1 9.0 7.1 8.6 11.5 10.7 9.0 7.0 8.9 4.0 8.2 4.0 10.2 9.6 2.9 3.9 8.6 5.2 4.0 9.5 10.6 3.7 7.9 14.2 8.7 10.5 9.9 8.9 10.1 1.5 5.4 7.8 7.2 12.9 14.2 21.2 13.8 21.8 5.7 5.6 42.7 20.4 9.1 19.1 13.0 21.6 16.3 19.9 15.6 7.7 15.3 52.1 10.0 14.3 3.8 25.9 16.3 17.6 59.7 11.6 9.6 19.9 36.2 7.8 9.7 21.6 7.9 5.3 8.9 25.9 29.2 20.6 7.0 25.8 21.0 35.8 22.5 12.9 26.0 38.0 16.5 28.2 6.0 12.4 17.6 17.5 16.8 17.0 10.6 6.1 27.2 22.8 12.0 35.3 22.9 41.7 23.2 12.5 26.8 20.7 15.4 18.1 20.7 1.1 2.1 3.1 1.3 2.2 1.1 0.5 1.2 1.2 1.7 1.0 0.6 0.6 2.9 0.7 1.7 1.1 1.8 1.5 8.7 9.6 7.9 12.5 8.3 7.1 10.7 9.0 10.2 7.9 9.9 12.9 1.4 0.0 2.6 13.4 3.9 0.5 0.7 1.0 5.2 0.4 1.5 1.3 1.6 1.5 1.6 3.7 0.0 4.5 1.4 3.3 1.9 1.1 0.8 1.3 1.9 1.8 2.4 1.3 8.6 1.1 3.5 1.6 5.1 2.1 1.3 2.0 1.1 0.8 2.5 0.0 7.5 1.9 2.0 3.2 1.3 1.1 0.6 2.7 1.8 6.5 5.4 0.1 5.2 3.5 10.5 1.6 1.5 0.4 6.9 0.7 2.6 1.2 0.3 0.9 0.0 0.9 1.4 1.9 1.2 3.2 0.3 3.7 3.8 1.6 2.2 0.8 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 128.8;skin 1: 134.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 12.1;Breast myoepithelial cells: 27.3;Exocrine glandular cells: 12.3;Granulosa cells: 68.7;Pancreatic endocrine cells: 15.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 229.2;hTCEpi: 139.2;RT4: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" NA NA 180000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" 4.4 4.0 14.8 4.7 25.6 24.3 8.2 17.4 32.3 14.0 0.0 12.4 16.6 3.4 2.3 128.8 4.0 3.4 8.1 30.5 15.3 5.1 4.3 3.4 2.1 23.8 26.5 2.3 18.8 2.7 7.8 7.3 18.4 12.8 12.9 18.5 18.0 6.2 1.9 134.4 12.0 4.5 16.3 3.3 4.6 1.3 26.9 6.7 2.2 1.6 27.9 28.9 36.8 38.8 16.6 13.6 12.6 18.2 6.5 2.1 88.2 6.6 6.1 5.4 3.8 28.8 55.2 21.8 26.1 7.6 10.9 229.2 32.5 117.6 2.4 51.8 4.9 3.0 4.4 13.2 2.6 14.9 35.4 2.0 139.2 17.1 62.5 2.1 16.3 6.2 0.6 113.2 7.2 42.7 0.3 9.0 41.6 55.3 18.7 1.2 75.7 26.3 5.1 157.4 30.6 68.6 22.1 57.4 1.8 18.8 52.3 2.2 9.0 4.8 17.6 39.2 5.9 20.6 28.0 0.2 1.7 11.9 11.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 1.6 0.0 0.0 14.8 25.6 17.4 32.3 30.5 15.3 23.8 26.5 18.4 16.3 26.9 38.8 4.2 0.0 3.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 12.1 27.3 0.0 0.0 4.3 1.8 0.0 4.1 4.1 0.0 0.0 8.7 0.0 4.6 3.2 1.3 0.0 0.0 0.0 12.3 1.3 2.1 0.0 10.9 0.0 68.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.5 0.0 0.0 1.9 0.0 0.0 3.3 1.5 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 8.9 1.3 1.7 0.0 0.0 NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 58.8;Endometrial stromal cells: 28.3;Fibroblasts: 22.8;Sertoli cells: 26.3;Smooth muscle cells: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;BJ hTERT+: 49.5;hTERT-RPE1: 42.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles, Cytosol" "CAB032859: AB_1128521, HPA031641: AB_10600826, HPA076526: AB_2686805" "unprognostic (3.51e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.84e-4)" "unprognostic (8.08e-2)" "unprognostic (1.67e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.39e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (1.81e-6)" "unprognostic (1.47e-2)" "unprognostic (1.07e-1)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" 48.4 54.9 9.1 6.0 9.4 0.6 47.2 8.6 10.5 126.0 9.0 71.9 4.5 82.1 13.7 22.2 82.6 17.8 30.2 9.0 9.3 35.5 5.6 30.2 4.8 10.3 9.4 142.7 13.8 9.0 37.9 18.2 8.8 51.5 5.0 2.8 20.5 16.2 9.0 25.0 29.9 18.8 8.2 17.7 35.5 42.7 9.7 1.7 50.4 2.5 3.6 66.2 65.9 8.5 0.0 0.1 17.8 0.0 25.4 36.8 0.1 17.3 49.5 23.0 20.0 0.0 14.6 14.9 0.5 25.0 1.6 0.0 7.1 0.3 13.9 0.0 0.6 11.3 20.6 0.0 12.3 0.0 0.0 26.8 0.3 13.9 0.1 42.5 18.2 4.7 3.7 0.0 4.5 0.8 0.0 1.7 2.3 1.0 0.1 1.1 1.6 2.0 0.0 0.2 2.9 11.9 0.0 3.3 5.7 8.7 10.3 4.5 10.3 21.3 4.4 20.5 0.0 10.4 1.6 11.0 4.4 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.4 8.6 10.5 9.0 9.3 10.3 9.4 8.8 8.2 9.7 8.5 4.1 3.2 8.1 58.8 1.1 4.5 0.9 1.9 0.6 1.3 3.3 2.8 7.8 0.0 4.8 0.0 0.0 0.6 0.0 0.8 0.0 2.8 4.4 2.5 28.3 4.6 7.7 0.0 0.1 0.2 0.6 22.8 3.6 6.4 0.0 4.1 1.4 0.2 0.6 0.0 0.2 3.4 10.2 0.0 6.8 6.5 17.4 0.4 7.2 13.1 0.0 7.6 0.0 1.0 0.2 0.6 0.3 7.5 0.2 0.8 0.4 0.2 2.1 1.5 26.3 4.3 27.1 12.5 2.9 1.0 3.4 0.5 0.9 6.0 1.6 2.3 NIBAN3 "BCNP1, FAM129C, FLJ39802" ENSG00000167483 "Niban apoptosis regulator 3" Q86XR2 19 17523301-17553839 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "bone marrow: 15.4;intestine: 16.6;lymphoid tissue: 34.7" "Cell type enriched" "Detected in some" 8 "B-cells: 11.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 31.9;naive B-cell: 52.1;plasmacytoid DC: 110.7" "Group enriched" "Detected in many" 476 "B-cells: 52.1;dendritic cells: 110.7" "Group enriched" "Detected in some" 19 "Daudi: 50.1;REH: 23.8;U-698: 33.2" "Not detected" "Not detected" HPA043277 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA043277: AB_10794391" "unprognostic (6.55e-5)" "unprognostic (3.03e-7)" "unprognostic (3.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.34e-1)" "unprognostic (1.69e-4)" "unprognostic (3.79e-3)" "unprognostic (1.69e-3)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (9.47e-4)" "unprognostic (8.42e-2)" "unprognostic (5.51e-5)" "unprognostic (3.39e-1)" "unprognostic (9.03e-3)" "unprognostic (6.08e-2)" "unprognostic (7.56e-3)" 0.4 0.0 0.0 10.7 0.1 15.4 0.1 0.0 0.2 0.1 0.0 0.8 0.0 0.1 0.0 0.4 0.1 1.0 0.1 0.0 0.0 0.5 0.3 0.4 26.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 16.6 0.0 0.0 34.7 0.7 0.5 0.0 1.8 0.6 0.0 12.2 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 0.0 0.0 0.0 52.1 0.0 0.1 0.0 0.0 0.0 110.7 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRP1 "CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1" ENSG00000091592 "NLR family pyrin domain containing 1" Q9C000 17 5499427-5619424 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 561.7;Muller glia cells: 151.8" "Cancer enhanced" "Detected in all" "glioma: 20.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 55.4;Karpas-707: 90.9;U-266/70: 45.0" "CAB009189, HPA064431" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Cytosol" "CAB009189: , HPA064431: AB_2685262" "unprognostic (4.40e-2)" "unprognostic (1.02e-1)" "unprognostic (3.16e-2)" "unprognostic (3.65e-2)" "unprognostic (4.00e-2)" "unprognostic (1.23e-3)" "unprognostic (4.13e-2)" "unprognostic (1.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "prognostic favorable (7.57e-4)" "unprognostic (2.99e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (6.69e-2)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (1.34e-2)" 27.9 4.0 3.6 27.8 3.7 25.0 22.1 3.2 5.3 22.9 3.5 10.8 5.8 13.8 1.8 16.2 14.4 13.4 15.7 2.9 3.7 9.4 5.3 26.9 38.1 5.5 3.8 5.8 3.2 1.8 4.1 12.1 5.5 13.2 7.8 0.3 10.8 9.0 7.7 50.8 31.1 9.7 3.7 56.3 6.9 6.1 4.0 15.1 21.8 7.7 32.4 15.8 27.7 4.1 14.2 0.0 0.0 0.0 8.6 10.2 1.8 6.9 6.3 2.6 5.7 0.2 5.5 5.3 20.8 7.6 1.1 6.5 0.0 23.4 4.0 55.4 0.0 1.4 4.8 0.5 7.1 0.0 1.6 6.6 14.5 20.7 13.7 10.4 25.6 1.1 13.0 90.9 11.8 0.0 0.1 4.6 0.0 0.0 0.3 6.0 4.0 23.0 0.0 4.8 0.7 0.0 0.0 0.2 0.4 0.6 0.0 0.5 25.2 5.3 3.0 3.2 1.1 45.0 15.9 4.1 8.7 0.6 0.3 18.3 7.1 5.0 5.9 4.9 6.6 4.4 5.1 6.3 5.0 4.9 5.5 5.2 18.9 4.2 8.6 0.5 7.7 4.6 3.6 3.7 3.2 5.3 2.9 3.7 5.5 3.8 5.5 3.7 4.0 4.1 46.4 0.0 7.8 1.3 29.0 17.7 7.1 8.0 15.4 60.6 2.7 6.2 4.9 2.8 10.4 7.3 4.2 0.8 30.3 0.3 3.9 0.4 561.7 4.9 18.0 26.9 77.9 3.6 2.9 0.0 1.1 31.6 3.6 1.0 3.8 7.8 44.6 0.6 7.0 85.8 1.5 1.2 0.0 23.0 24.3 93.4 25.4 26.2 7.2 56.2 27.0 151.8 26.8 1.5 0.8 7.0 0.0 28.2 25.9 2.0 0.0 0.4 12.7 11.6 6.6 33.1 17.3 25.0 11.0 10.7 24.9 1.5 37.6 3.6 0.2 8.0 NLRP13 "CLR19.7, NALP13, NOD14, PAN13" ENSG00000173572 "NLR family pyrin domain containing 13" Q86W25 19 55891699-55932336 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060459 Uncertain NA NA "Cluster 64: Astrocytes - Nervous system maintenance" "HPA060459: AB_2684284" "unprognostic (2.16e-1)" "unprognostic (4.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "parathyroid gland: 22.4" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Karpas-707: 1.3;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 22.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NLRP8 "CLR19.2, NALP8, NOD16, PAN4" ENSG00000179709 "NLR family pyrin domain containing 8" Q86W28 19 55947832-55988629 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 15.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056989 Uncertain NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056989: AB_2683301" "unprognostic (2.43e-2)" "unprognostic (3.35e-1)" "unprognostic (3.13e-1)" "unprognostic (6.96e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.5;heart muscle: 18.3;pituitary gland: 18.4" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 195.5;Inhibitory neurons: 265.4;Oligodendrocyte precursor cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 26.2;SCLC-21H: 80.6;SuSa: 25.1;U-2197: 45.8;U-87 MG: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015708, HPA061714" Enhanced Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA015708: , HPA061714: AB_2732669" "unprognostic (3.70e-1)" "unprognostic (7.98e-3)" "unprognostic (8.83e-2)" "unprognostic (4.16e-2)" "unprognostic (8.95e-2)" "unprognostic (9.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.35e-1)" "unprognostic (7.92e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.73e-3)" "unprognostic (2.90e-3)" "unprognostic (1.87e-1)" "unprognostic (7.51e-2)" "unprognostic (1.02e-1)" 8.5 5.9 13.1 0.8 14.8 0.0 5.1 17.2 45.5 2.1 0.0 2.3 0.4 1.2 1.4 0.8 2.3 2.8 18.3 15.6 21.4 0.4 0.0 0.7 0.6 0.7 0.8 0.4 1.7 0.2 18.4 0.9 6.7 0.2 0.9 6.5 0.5 2.5 0.5 0.9 0.9 1.5 0.0 0.1 1.1 8.9 0.8 0.5 6.0 1.4 0.6 0.7 0.8 10.0 1.4 0.5 5.5 0.0 3.1 12.5 4.6 3.4 8.9 1.8 0.6 2.7 5.4 0.0 14.2 0.8 1.5 2.2 0.2 0.1 3.3 0.0 0.1 0.0 2.2 0.0 0.5 0.0 0.1 26.2 1.1 2.1 0.5 11.1 0.5 0.0 0.0 0.1 2.1 0.1 0.0 0.5 9.7 0.1 5.4 0.0 0.2 0.0 5.9 4.5 80.6 6.2 0.7 0.3 0.0 25.1 0.7 1.5 3.0 2.5 0.9 45.8 3.3 0.6 0.0 0.0 35.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 14.8 17.2 45.5 15.6 21.4 0.7 0.8 6.7 0.0 0.8 10.0 21.4 0.0 1.5 3.9 0.0 0.8 0.2 0.6 0.6 12.1 0.2 0.1 35.2 0.0 2.0 0.0 0.0 0.7 0.1 0.1 0.0 0.2 54.3 2.7 0.3 5.2 0.0 0.0 195.5 0.0 12.9 5.7 0.0 7.4 0.0 0.2 0.0 0.0 0.7 20.2 265.4 0.0 4.1 1.0 0.0 42.3 0.0 0.5 1.8 11.2 0.0 0.3 0.0 98.5 6.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 3.4 2.9 19.7 0.3 12.0 0.4 0.2 0.1 0.3 1.4 0.2 0.0 0.0 0.0 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 135.7" "Cell type enriched" "Detected in some" 45 "Extravillous trophoblasts: 1002.5" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Hep G2: 428.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" NA NA 1900000 "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" 0.0 0.1 1.6 0.0 1.9 0.0 0.2 0.6 1.8 0.2 0.1 0.0 1.1 2.1 0.3 0.3 0.4 0.2 0.3 1.0 1.0 1.2 10.0 2.2 0.0 1.7 2.7 0.1 0.4 0.9 0.2 135.7 1.3 0.3 0.0 0.0 0.6 0.1 8.2 2.2 0.3 0.1 0.9 0.2 2.1 2.8 1.3 0.0 0.0 0.5 0.0 1.4 0.2 0.8 0.0 1.2 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 10.0 0.4 0.0 1.8 0.3 0.2 0.4 2.4 0.0 0.0 0.1 1.1 2.2 2.8 428.6 0.2 0.4 0.4 0.2 0.0 0.0 0.0 0.6 0.0 0.2 11.2 0.0 0.0 0.6 0.0 0.2 0.1 67.9 0.4 0.0 0.2 0.1 0.0 0.2 15.7 1.6 4.2 1.7 6.2 2.3 0.1 4.9 0.0 0.5 6.3 0.0 0.2 0.1 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.6 1.8 1.0 1.0 1.7 2.7 1.3 0.9 1.3 0.8 0.0 0.0 3.7 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.6 1.3 1.2 0.0 0.0 0.0 0.0 10.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.8 0.0 0.0 0.6 0.0 1002.5 1.2 1.5 0.3 0.0 0.1 0.0 3.6 18.4 0.0 1.1 0.1 0.0 0.0 0.3 0.2 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.5 12.7 0.0 0.0 22.0 0.1 0.0 0.3 0.0 NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 138.0" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 164.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 14.3;HUVEC TERT2: 27.7;TIME: 70.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" 7.8 0.7 0.7 0.7 1.2 0.2 3.8 0.7 1.2 1.5 0.0 1.2 0.2 4.9 0.4 0.4 1.3 2.4 7.6 0.4 0.6 138.0 0.3 1.5 0.2 1.0 0.7 0.8 0.3 3.6 0.9 3.1 0.9 1.0 0.3 17.1 3.0 1.3 1.7 1.4 0.6 3.4 0.8 0.4 0.5 0.3 0.7 0.1 2.1 3.5 0.5 1.4 1.1 1.7 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.5 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.1 14.3 27.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 6.1 0.0 0.0 0.3 7.1 0.4 0.0 70.6 0.2 5.0 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 1.2 0.7 1.2 0.4 0.6 1.0 0.7 0.9 0.8 0.7 1.7 4.4 0.0 0.0 2.9 1.0 0.6 0.1 0.4 0.0 7.5 0.2 0.3 1.0 0.0 0.0 11.0 6.2 2.2 0.2 0.1 15.6 0.0 0.8 1.0 1.4 5.9 0.0 0.0 30.0 0.0 0.8 9.2 0.0 3.0 0.0 0.6 2.5 0.1 0.2 0.0 21.1 0.0 0.0 0.0 0.5 0.7 0.3 1.3 0.0 6.5 0.1 4.5 0.0 7.1 28.4 0.1 0.0 1.2 0.3 0.1 0.0 164.0 0.0 27.1 0.0 1.2 1.0 0.6 0.7 0.1 0.3 2.5 1.1 0.1 0.0 0.1 NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;skin 1: 7.7" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 16.7;Gastric mucus-secreting cells: 27.0;Inhibitory neurons: 28.3" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 9.9;Daudi: 10.2;HEK 293: 11.1;HMC-1: 9.0;NB-4: 18.1;U-266/84: 11.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" 0.9 0.4 3.1 0.3 1.8 0.2 0.7 0.3 6.3 0.4 1.9 0.4 0.0 0.1 0.0 1.0 0.6 0.0 1.1 5.4 2.8 1.7 0.6 0.4 0.5 2.9 2.5 0.2 0.6 0.0 1.3 0.1 4.3 0.4 0.0 0.5 0.4 0.0 0.1 7.7 0.4 0.1 0.7 2.8 2.7 0.6 1.5 0.1 0.5 0.0 0.3 0.4 0.7 2.0 0.2 2.4 0.3 0.5 0.2 0.2 0.0 9.9 0.3 0.1 0.4 0.7 0.5 10.2 2.2 8.1 0.4 0.2 2.1 0.2 0.1 0.7 11.1 0.8 1.2 2.5 0.0 5.5 9.0 0.9 0.4 0.0 0.1 0.6 0.2 1.3 3.5 0.8 1.3 0.9 0.4 18.1 2.4 0.4 1.7 0.9 0.4 0.8 0.6 0.6 0.7 0.6 0.8 0.3 2.4 0.8 2.1 1.7 0.1 0.2 0.9 0.1 0.2 5.4 11.5 2.2 1.2 1.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 0.3 6.3 5.4 2.8 2.9 2.5 4.3 0.7 1.5 2.0 0.1 0.0 0.6 1.6 1.1 0.8 1.4 1.1 1.8 0.7 2.2 2.5 1.1 0.0 1.1 0.0 16.7 0.0 0.1 0.3 0.0 0.6 0.1 0.4 0.2 0.2 1.2 2.7 5.7 0.4 0.1 0.5 27.0 0.4 0.0 0.7 0.0 0.1 0.3 0.0 28.3 1.4 2.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 5.4 0.0 2.0 1.2 1.0 0.2 0.0 2.6 1.5 0.0 0.9 2.0 5.4 0.0 0.1 1.1 0.4 2.1 2.2 2.3 0.0 1.2 0.1 0.6 1.2 NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 21 "epididymis: 16783.1" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2034.2;Hofbauer cells: 2898.5;Kupffer cells: 2035.4" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 668.7;classical monocyte: 1300.7;intermediate monocyte: 1772.7;myeloid DC: 587.8;neutrophil: 674.2;non-classical monocyte: 1252.1;plasmacytoid DC: 2113.2" "Group enriched" "Detected in all" 5 "dendritic cells: 2113.2;granulocytes: 674.2;monocytes: 1772.7" "Cell line enhanced" "Detected in all" "ASC diff: 1619.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" NA NA 53000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" 260.1 297.0 127.1 261.3 145.4 305.3 221.3 152.2 190.6 284.5 434.0 259.7 201.7 196.7 16783.1 185.0 170.0 356.0 215.1 118.1 156.9 322.4 202.4 786.0 360.3 185.7 145.6 283.1 219.9 241.3 197.5 263.1 179.2 164.2 220.8 48.6 221.9 261.3 58.7 181.6 193.3 180.5 151.1 305.6 206.8 156.8 172.1 134.4 444.7 114.7 241.9 347.4 187.9 195.5 297.2 199.3 124.8 179.4 1619.3 498.6 404.8 194.1 707.1 200.9 398.9 351.7 420.3 78.6 141.6 181.9 372.6 595.9 170.0 405.5 188.6 120.4 126.3 29.6 96.7 296.2 348.6 51.0 548.4 467.7 388.9 173.7 336.9 930.2 298.1 87.0 32.9 601.4 224.0 106.9 70.1 75.9 52.9 489.0 307.9 39.5 219.1 281.6 511.1 735.0 5.5 91.3 296.3 120.3 298.0 359.6 205.2 225.7 268.9 291.9 342.0 396.1 188.2 253.7 452.5 24.2 292.1 168.4 163.4 668.7 1300.7 274.1 92.2 1772.7 87.9 295.2 126.5 92.3 587.8 241.8 120.9 100.5 674.2 99.5 1252.1 2113.2 187.8 1304.5 127.1 145.4 152.2 190.6 118.1 156.9 185.7 145.6 179.2 151.1 172.1 195.5 154.9 381.4 2034.2 11.1 160.2 374.9 557.8 1074.2 170.2 9.9 138.6 220.5 55.4 163.0 626.9 331.1 22.9 228.3 664.0 301.0 305.2 500.4 90.9 123.8 168.5 276.5 119.7 65.4 2.1 279.4 803.3 318.1 61.7 161.0 341.4 104.2 447.3 195.6 2898.5 8.4 3.8 264.8 832.1 2035.4 750.9 69.6 566.7 1462.6 602.9 6.5 790.5 167.4 117.4 7.5 24.4 368.3 405.1 291.9 287.4 357.9 298.1 969.0 393.3 25.1 131.5 118.3 155.9 268.1 166.7 182.6 320.7 210.4 109.9 330.0 298.5 521.6 NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.6;Hofbauer cells: 54.4;Kupffer cells: 100.9;Proximal enterocytes: 69.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC TERT1: 45.3;HSkMC: 61.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" 60.7 19.9 11.3 19.4 11.8 3.3 51.1 11.2 14.3 25.3 10.2 24.6 48.4 13.6 17.6 7.6 20.3 19.6 18.5 10.3 11.1 23.4 83.8 24.1 46.7 11.0 12.1 15.2 16.7 6.8 7.2 25.4 11.7 19.4 12.0 2.2 14.8 11.5 9.1 11.7 41.0 7.9 10.5 53.2 16.3 21.8 13.8 11.0 20.3 6.3 13.6 22.4 17.5 11.5 3.5 13.8 6.4 6.1 41.0 45.3 31.1 3.5 17.9 5.7 8.8 17.0 43.2 6.1 6.5 2.8 2.1 9.2 7.6 6.1 3.8 5.8 6.1 8.3 18.7 26.1 17.5 2.9 1.0 61.2 3.7 8.7 5.5 9.7 5.0 9.4 10.2 2.5 4.5 14.8 5.8 17.0 7.1 18.7 4.5 8.4 8.3 4.1 5.0 31.9 6.1 2.3 12.2 7.9 10.4 6.1 19.5 8.8 1.3 4.5 6.1 9.1 2.0 11.9 18.3 7.6 8.2 3.9 2.2 7.8 2.7 2.5 1.4 13.3 1.9 1.0 1.5 1.3 4.3 0.7 1.7 1.4 1.6 5.8 4.2 0.7 3.8 1.9 11.3 11.8 11.2 14.3 10.3 11.1 11.0 12.1 11.7 10.5 13.8 11.5 27.2 0.0 11.3 8.1 3.0 3.3 8.6 4.6 2.2 2.4 12.7 12.1 6.6 15.7 4.9 5.5 2.1 11.0 1.5 24.4 11.7 5.8 31.0 2.4 15.3 12.5 1.8 7.0 9.2 8.7 13.3 14.1 17.9 2.8 13.3 7.1 24.7 66.6 54.4 1.7 10.9 14.6 2.0 100.9 3.3 49.0 9.0 24.7 3.6 1.0 5.4 4.4 2.1 3.0 5.6 4.2 10.7 6.0 2.4 4.1 69.5 26.1 2.5 0.8 19.7 7.4 16.3 32.4 16.8 3.0 2.4 6.6 2.1 5.4 19.0 6.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NSG1 "D4S234E, NEEP21, P21" ENSG00000168824 "Neuronal vesicle trafficking associated 1" P42857 4 4348140-4419058 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.7;pituitary gland: 135.1;skin 1: 120.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 222.4;Cytotrophoblasts: 120.2;Granulosa cells: 128.8;Melanocytes: 291.7;Suprabasal keratinocytes: 178.2" "Cancer enriched" "Detected in many" 4 "melanoma: 61.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 45.2;MAIT T-cell: 61.9;memory CD4 T-cell: 42.2;memory CD8 T-cell: 37.1;naive CD8 T-cell: 27.6" "Lineage enriched" "Detected in many" 57 "T-cells: 61.9" "Cell line enhanced" "Detected in many" "HAP1: 84.7;SCLC-21H: 168.6;SH-SY5Y: 82.5;SK-MEL-30: 80.9;TIME: 204.6;U-698: 75.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "unprognostic (3.21e-3)" "unprognostic (2.33e-1)" "unprognostic (5.29e-3)" "unprognostic (7.60e-2)" "unprognostic (8.06e-2)" "unprognostic (1.49e-1)" "unprognostic (1.32e-3)" "unprognostic (3.47e-2)" "unprognostic (2.06e-1)" "unprognostic (1.91e-3)" "prognostic favorable (9.49e-4)" "unprognostic (2.50e-1)" "unprognostic (6.85e-2)" "unprognostic (4.21e-2)" "unprognostic (7.33e-2)" "unprognostic (2.85e-1)" "unprognostic (7.41e-2)" 5.0 25.3 29.0 4.2 33.1 1.0 6.0 59.6 50.7 17.1 5.3 7.9 6.8 7.8 2.1 30.7 20.1 1.3 5.9 18.4 95.7 4.4 0.5 1.5 3.2 57.1 64.8 46.3 1.8 0.1 135.1 18.3 58.8 22.8 7.1 32.3 6.7 18.2 0.7 120.9 5.8 6.9 24.2 2.2 8.0 16.0 45.4 9.5 0.5 3.0 3.5 13.3 30.1 24.2 0.2 0.1 0.8 0.5 0.0 0.0 14.6 0.3 0.0 0.2 0.0 1.3 0.4 0.0 10.4 0.5 3.3 2.4 84.7 5.5 0.4 0.0 3.0 0.0 0.2 0.0 4.1 0.0 0.0 0.1 12.0 0.0 2.3 0.0 14.6 22.3 0.0 0.1 1.3 0.0 6.8 0.5 10.1 0.1 0.4 0.1 0.0 0.4 0.0 4.8 168.6 82.5 0.6 0.2 80.9 7.0 0.9 0.3 204.6 0.0 13.0 0.2 0.3 0.1 0.4 75.9 0.1 0.2 0.4 0.2 0.1 0.1 45.2 0.1 61.9 0.1 42.2 37.1 0.1 0.1 10.4 27.6 1.0 0.9 0.2 0.1 4.5 15.7 29.0 33.1 59.6 50.7 18.4 95.7 57.1 64.8 58.8 24.2 45.4 24.2 1.6 9.6 0.0 5.9 0.4 86.8 83.4 47.9 31.3 222.4 0.7 24.3 0.0 0.0 13.2 0.0 4.2 120.2 6.0 0.0 0.0 0.0 31.2 10.3 1.4 2.1 2.4 0.0 16.6 0.0 15.2 24.9 0.0 16.4 1.3 128.8 1.8 0.0 8.2 8.4 32.2 0.0 4.1 0.0 13.6 44.2 3.1 1.3 291.7 6.5 0.4 6.4 20.6 1.5 4.0 0.1 0.2 5.7 0.7 19.9 0.0 20.4 1.7 24.3 0.0 0.2 10.8 2.9 14.4 44.8 178.2 76.8 17.0 96.0 0.3 77.0 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTN1 NTN1L ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1;heart muscle: 59.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 137.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 27.5;T-47d: 16.6;U-2 OS: 14.4;U-251 MG: 22.1;WM-115: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" NA NA 110000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" 6.4 0.5 4.5 3.6 6.4 0.1 5.3 10.1 4.9 9.3 2.8 14.7 6.7 9.6 3.5 18.9 10.3 7.3 59.4 3.8 7.0 2.0 6.9 4.3 0.2 12.7 37.1 0.9 2.3 4.3 3.0 0.9 14.4 3.9 3.9 0.4 10.9 2.0 2.1 8.1 10.5 6.0 13.8 0.1 17.5 3.1 10.1 2.9 2.0 2.6 2.1 10.2 5.4 8.8 0.1 0.0 1.3 4.6 4.2 0.1 27.5 0.3 0.4 0.3 0.5 0.1 5.7 0.0 6.2 0.0 9.0 0.1 1.2 0.9 0.0 6.4 10.4 1.4 0.0 0.0 0.1 0.5 0.1 0.1 2.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 5.6 0.1 0.6 1.8 0.0 0.0 3.4 4.8 0.0 0.0 0.3 0.0 0.0 0.1 4.7 1.1 4.5 16.6 0.3 0.0 6.7 14.4 0.0 22.1 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 6.4 10.1 4.9 3.8 7.0 12.7 37.1 14.4 13.8 10.1 8.8 0.7 0.0 0.0 10.7 0.3 3.3 6.6 21.8 9.6 2.9 4.7 4.4 28.1 0.0 23.9 1.8 0.0 0.3 0.2 0.5 0.0 3.1 9.3 5.8 2.0 3.1 0.0 0.0 4.8 1.7 1.2 9.7 1.1 7.9 0.0 0.0 2.2 12.4 0.1 0.0 7.1 1.4 24.4 0.6 5.9 4.6 0.3 0.1 1.8 9.4 0.6 0.3 0.0 137.2 1.0 1.4 0.1 0.0 0.0 4.0 0.7 0.2 11.1 0.2 0.0 3.9 6.8 1.6 2.0 12.7 2.8 0.5 0.5 0.0 0.6 3.5 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 11.4;Endometrial ciliated cells: 39.1;Glandular and luminal cells: 13.9;Granulosa cells: 13.2;Proximal tubular cells: 18.6;Theca cells: 12.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 7.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA045526: AB_10961044" "prognostic favorable (6.53e-4)" "unprognostic (9.70e-2)" "unprognostic (4.78e-3)" "prognostic favorable (3.83e-8)" "unprognostic (2.70e-2)" "unprognostic (3.19e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-4)" "unprognostic (1.92e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-3)" "unprognostic (5.58e-2)" "prognostic favorable (9.60e-4)" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-2)" 6.5 0.7 4.3 1.2 3.4 4.2 2.8 6.0 5.5 4.0 1.8 0.5 0.9 2.0 1.3 0.4 4.3 1.0 0.7 3.4 3.4 2.3 4.5 0.7 0.9 0.7 1.2 1.1 0.4 0.3 0.1 0.6 1.4 0.9 0.4 4.8 1.6 0.7 1.3 1.5 0.9 0.4 0.4 1.1 0.8 1.3 3.6 0.5 1.3 0.1 0.5 0.4 0.3 5.1 1.5 2.6 1.0 1.0 0.1 0.7 0.7 2.6 0.7 0.3 0.5 0.6 1.0 0.6 1.1 0.3 0.7 1.3 0.4 0.1 0.9 0.4 0.8 1.3 4.0 1.0 0.4 0.7 1.1 0.5 0.2 0.3 0.2 0.4 0.0 0.9 0.9 2.7 0.7 0.7 0.7 1.2 1.4 0.5 0.7 0.5 0.5 0.9 10.4 0.8 0.6 0.4 1.6 0.8 0.5 0.7 1.2 0.6 0.9 0.9 1.9 1.5 0.6 0.9 0.8 0.7 0.7 0.9 0.7 2.1 0.3 0.8 0.6 0.1 0.6 0.2 0.3 0.7 0.0 0.3 0.6 0.7 0.8 0.5 0.1 0.3 0.6 0.3 4.3 3.4 6.0 5.5 3.4 3.4 0.7 1.2 1.4 0.4 3.6 5.1 0.2 0.0 0.0 1.3 0.1 0.0 1.9 0.7 1.2 0.2 7.5 3.2 0.3 4.3 0.1 1.8 0.0 0.2 0.0 0.0 1.9 0.8 11.4 39.1 4.3 0.8 0.0 0.0 1.2 0.2 1.3 0.8 0.0 13.9 0.0 13.2 0.0 0.1 0.2 0.0 1.9 0.0 0.0 0.0 0.0 4.4 0.9 0.2 0.0 0.0 0.0 0.5 0.0 1.0 0.7 0.2 0.0 2.2 0.1 0.4 0.0 18.6 0.2 0.8 0.0 0.3 1.3 0.4 1.6 0.0 0.1 1.1 0.3 12.7 0.0 2.2 OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 396.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.9;Fibroblasts: 135.9;Hepatocytes: 218.8;Muller glia cells: 279.4;Theca cells: 149.0;Urothelial cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 115.5;Hep G2: 190.1;NB-4: 139.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 69000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" 66.0 91.5 47.7 18.0 56.8 10.8 42.6 35.8 57.1 66.7 40.5 61.9 47.7 54.2 16.0 22.8 54.6 34.5 55.1 48.1 36.5 51.4 396.6 19.2 5.8 39.0 37.8 61.0 74.1 6.7 27.4 8.1 37.1 33.5 36.5 30.7 53.9 13.7 13.2 12.0 57.3 29.1 35.9 54.4 33.5 3.7 45.0 4.6 25.9 12.2 3.7 42.6 40.4 44.6 24.9 7.5 30.9 14.4 47.8 53.4 1.7 47.7 53.8 20.5 30.0 7.5 37.3 0.0 115.5 35.6 33.7 25.7 8.9 13.2 8.2 18.7 21.1 21.1 4.7 190.1 42.4 46.7 7.9 66.8 7.9 19.8 54.8 39.9 59.7 12.7 14.0 22.7 5.0 9.4 0.3 139.9 11.6 7.3 40.8 11.8 0.9 23.7 31.8 13.4 1.5 10.0 14.0 15.2 40.2 8.6 4.8 74.7 32.7 39.3 14.7 40.8 4.6 0.8 0.7 0.4 30.3 76.2 14.1 0.0 3.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.2 0.1 0.0 0.3 0.5 0.1 0.8 47.7 56.8 35.8 57.1 48.1 36.5 39.0 37.8 37.1 35.9 45.0 44.6 19.4 0.0 0.6 102.2 3.7 9.4 33.6 7.3 12.5 3.2 6.0 7.0 5.5 34.3 3.5 71.7 2.1 2.1 1.1 135.9 27.4 14.8 0.2 4.7 70.9 40.0 22.8 12.8 0.6 28.7 5.5 135.9 11.7 12.2 1.3 2.6 12.5 218.8 6.0 0.0 2.3 56.5 4.1 11.5 20.9 1.1 16.8 11.0 16.0 23.4 10.2 279.4 0.0 5.5 11.0 28.2 56.5 4.5 14.5 31.3 111.1 79.3 0.4 10.6 52.6 8.6 40.8 0.7 6.9 11.3 10.2 6.2 3.1 149.0 45.8 192.5 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OR2I1P "HS6M1-14, OR2I1, OR2I2, OR2I3P, OR2I4P" ENSG00000237988 "Olfactory receptor family 2 subfamily I member 1 pseudogene" 6 29550407-29557721 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Ductal cells: 1.0;granulocytes: 1.3;monocytes: 1.0" "Cancer enhanced" "Detected in all" "liver cancer: 71.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 3: Monocytes - Immune response regulation" "unprognostic (7.45e-3)" "unprognostic (1.69e-2)" "unprognostic (6.00e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.60e-2)" "unprognostic (1.07e-3)" "unprognostic (3.29e-1)" "unprognostic (2.23e-1)" "unprognostic (5.34e-3)" "prognostic favorable (5.58e-4)" "unprognostic (1.32e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (4.00e-6)" "unprognostic (8.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 214.3;Oligodendrocytes: 433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.4" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040959: AB_10964295, HPA043401: AB_10960208" "unprognostic (1.75e-2)" "unprognostic (3.35e-2)" "unprognostic (9.84e-3)" "unprognostic (4.92e-3)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (5.88e-2)" "unprognostic (2.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "prognostic favorable (4.98e-13)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.18e-2)" "unprognostic (5.42e-3)" "unprognostic (1.56e-1)" 72.0 27.8 77.1 9.4 105.6 15.4 47.9 99.6 136.0 52.4 114.0 34.9 20.7 48.0 17.2 30.8 29.6 21.1 52.0 77.3 90.6 43.5 13.3 24.2 10.4 89.7 95.0 27.3 16.5 62.8 18.7 8.3 94.5 23.0 22.7 82.2 51.5 26.2 170.9 17.5 20.2 41.1 79.2 9.9 21.3 14.3 91.3 9.6 29.0 123.1 7.9 25.4 20.0 136.8 38.2 11.4 26.3 49.1 60.0 48.7 24.5 14.0 40.4 12.4 10.2 7.1 38.9 0.1 16.0 25.1 19.7 37.9 10.4 24.4 11.4 0.2 19.6 12.1 7.8 0.2 29.9 30.4 6.0 63.4 34.4 9.5 38.4 54.0 15.9 10.4 0.0 0.3 15.5 16.1 7.0 9.1 21.7 19.5 36.8 0.0 21.0 3.2 3.3 27.7 16.9 16.6 32.6 37.5 46.1 24.5 13.7 21.7 3.4 45.9 9.4 14.9 13.6 0.4 5.3 1.0 22.3 8.7 26.8 93.4 4.2 1.1 0.2 2.2 0.1 0.0 0.8 0.6 4.1 0.4 0.6 0.5 1.6 0.2 0.7 4.1 0.8 1.5 77.1 105.6 99.6 136.0 77.3 90.6 89.7 95.0 94.5 79.2 91.3 136.8 214.3 16.0 21.6 142.0 5.4 20.1 43.4 16.6 29.6 66.6 73.6 64.3 78.0 41.5 20.0 20.2 22.9 12.1 11.1 23.6 64.6 13.3 67.7 27.6 55.3 89.9 4.8 18.7 180.3 7.4 8.1 59.9 16.3 17.0 17.2 137.9 37.5 12.4 26.6 25.2 166.4 40.0 40.7 27.4 17.9 76.4 42.9 34.3 58.7 67.5 11.0 124.8 0.0 75.9 433.0 10.7 19.1 54.9 2.5 27.1 29.8 71.7 21.7 112.3 32.9 44.7 65.8 6.7 9.9 27.2 10.2 6.4 3.8 103.7 16.2 26.4 OSTF1 "bA235O14.1, OSF, SH3P2" ENSG00000134996 "Osteoclast stimulating factor 1" Q92882 9 75088514-75147265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 329.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 302.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020514 Approved Supported Cytosol NA NA 580000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA020514: AB_2670461" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (7.54e-2)" "prognostic favorable (3.67e-5)" "unprognostic (1.36e-1)" "unprognostic (2.43e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-3)" "unprognostic (3.76e-1)" "unprognostic (7.89e-2)" "unprognostic (6.36e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (1.53e-1)" 44.3 36.9 27.8 65.7 35.0 56.3 34.9 32.0 37.2 34.1 25.4 42.5 38.2 22.7 38.2 104.8 20.0 42.8 32.0 28.3 33.2 34.6 57.7 56.4 74.9 31.0 32.5 16.0 19.4 72.1 19.1 69.9 33.1 22.7 45.8 12.3 38.5 19.6 9.5 63.1 47.8 28.8 30.8 87.0 40.6 18.0 31.0 47.8 29.0 16.0 85.0 55.3 53.9 35.1 69.1 16.0 7.7 11.2 45.4 41.7 81.3 71.9 46.9 26.9 24.4 8.2 50.8 70.9 35.3 59.2 34.6 111.8 12.9 51.9 77.0 302.0 16.0 39.3 24.8 42.5 36.7 71.5 141.6 29.1 49.2 31.6 21.8 23.7 91.2 59.4 13.4 158.4 65.4 35.9 107.5 44.8 14.5 161.5 30.8 20.1 52.3 63.0 57.0 97.1 6.5 0.6 53.1 74.1 36.2 58.2 97.4 79.9 86.4 55.8 19.4 108.3 30.8 30.1 52.5 26.7 67.1 81.9 46.4 359.5 177.7 464.8 158.6 199.3 169.6 101.2 110.5 131.5 148.7 87.4 62.1 109.8 495.2 168.4 256.8 110.6 163.0 283.0 27.8 35.0 32.0 37.2 28.3 33.2 31.0 32.5 33.1 30.8 31.0 35.1 113.4 22.4 24.4 8.1 90.8 82.2 61.2 78.2 61.5 2.9 38.6 23.2 7.8 28.6 51.2 33.1 6.2 125.5 162.1 64.8 76.3 49.7 11.9 42.8 59.4 60.5 27.2 23.3 32.0 52.3 252.9 42.1 31.1 51.1 137.6 4.2 71.7 32.2 233.1 10.1 12.6 31.9 69.2 167.4 181.5 6.0 23.9 155.7 76.5 43.1 329.9 6.0 268.8 30.2 67.3 60.5 97.7 15.4 83.2 34.1 64.1 63.0 27.3 8.6 19.7 15.9 45.0 6.7 17.8 141.4 114.5 133.9 163.8 37.6 38.2 91.6 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 P2RX5 "LRH-1, P2X5" ENSG00000083454 "Purinergic receptor P2X 5" Q93086 17 3672199-3696240 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.7;lymphoid tissue: 78.2" "Group enriched" "Detected in some" 4 "B-cells: 94.6;Plasma cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "memory B-cell: 76.4;naive B-cell: 84.8" "Lineage enriched" "Detected in many" 20 "B-cells: 84.8" "Cell line enhanced" "Detected in many" "Daudi: 53.2;Karpas-707: 32.7;RPMI-8226: 59.5;U-698: 47.1" "HPA021948, HPA067827" Supported Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "HPA021948: AB_1854878, HPA067827: AB_2685908" "unprognostic (1.08e-3)" "unprognostic (9.16e-2)" "unprognostic (1.40e-2)" "unprognostic (5.81e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (8.33e-2)" "unprognostic (4.34e-1)" "unprognostic (1.24e-1)" "unprognostic (1.14e-1)" "unprognostic (2.15e-1)" "unprognostic (2.42e-2)" "unprognostic (1.99e-8)" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (3.50e-2)" "unprognostic (3.63e-2)" 0.8 0.3 1.8 30.4 2.2 9.4 0.8 0.2 2.7 0.3 0.0 2.4 1.5 0.1 0.0 0.7 0.3 1.3 8.0 2.1 0.9 0.7 0.5 1.4 78.2 0.6 0.5 0.0 0.2 0.2 1.2 0.2 0.7 0.5 1.9 0.4 1.8 0.0 17.5 0.0 24.7 0.5 0.1 54.4 3.4 0.7 1.1 12.1 0.9 4.0 53.9 2.7 0.3 1.4 8.3 6.7 0.0 0.0 0.2 1.3 0.0 8.4 3.9 0.9 2.6 5.5 9.8 53.2 4.9 4.2 2.9 4.3 18.8 0.0 1.7 0.9 3.2 2.7 17.5 6.3 1.2 3.6 4.2 2.1 1.8 0.2 12.4 6.5 0.0 12.2 0.5 32.7 18.2 0.0 23.4 8.1 4.9 4.4 20.5 0.8 0.0 59.5 0.2 6.3 4.3 0.0 7.5 2.5 3.9 0.0 2.0 3.3 0.1 0.0 4.5 0.2 1.5 11.0 25.2 47.1 0.0 5.1 0.5 0.0 0.1 2.0 3.1 0.0 4.2 76.4 2.8 2.2 0.4 84.8 0.3 0.3 0.0 0.0 0.0 0.1 1.9 4.5 1.8 2.2 0.2 2.7 2.1 0.9 0.6 0.5 0.7 0.1 1.1 1.4 0.1 0.0 0.6 0.0 94.6 0.4 0.1 0.0 0.0 0.8 0.1 0.1 2.7 0.0 0.0 1.8 0.0 0.0 13.4 0.0 0.0 0.2 4.8 0.2 0.2 0.7 0.0 11.1 0.0 0.2 0.0 0.3 0.5 0.3 4.5 0.0 1.4 0.4 0.2 0.0 0.0 0.1 0.0 1.2 0.0 3.1 1.5 1.6 3.6 0.0 1.1 0.0 2.1 0.0 0.0 1.5 0.0 0.0 29.7 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.9 1.0 0.8 0.0 0.0 0.0 11.0 0.0 0.1 0.1 PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Astrocytes: 380.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 86.9;ASC TERT1: 354.7;BJ hTERT+: 357.7;fHDF/TERT166: 86.7;HSkMC: 123.1;U-87 MG: 82.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" NA NA 5600000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" 32.8 14.9 25.1 0.6 27.4 0.0 15.4 22.0 23.2 59.9 13.9 14.9 4.5 58.2 18.3 10.0 22.6 20.3 23.2 22.5 26.2 7.1 12.6 5.9 1.3 37.9 35.9 3.4 5.3 1.7 6.4 55.9 32.4 21.2 6.6 0.9 5.7 17.9 2.7 19.8 9.9 14.9 46.1 5.7 5.4 0.2 34.1 2.8 7.0 9.0 1.7 28.0 41.3 38.8 0.0 0.0 0.1 0.0 86.9 354.7 0.1 42.8 357.7 4.9 8.3 32.7 0.0 0.0 0.0 86.7 0.1 0.1 0.0 0.0 3.3 0.0 0.8 0.0 0.0 0.0 50.1 0.0 0.0 123.1 1.8 9.7 1.3 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.7 0.0 0.2 0.0 0.2 0.2 0.0 8.4 0.1 0.0 0.0 0.0 0.0 14.3 2.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.1 0.0 82.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 27.4 22.0 23.2 22.5 26.2 37.9 35.9 32.4 46.1 34.1 38.8 2.5 0.0 0.0 380.3 0.0 19.1 1.4 14.8 1.2 0.1 0.7 19.7 1.3 0.0 2.4 1.8 0.0 2.2 0.0 0.0 0.0 1.4 0.1 4.5 26.2 1.1 0.0 0.0 13.1 0.0 1.4 50.2 1.1 0.8 0.0 0.6 0.0 0.0 2.0 0.0 8.2 0.2 0.0 0.0 5.5 0.1 0.3 0.5 1.8 28.1 0.6 0.0 0.0 9.5 1.4 0.1 0.0 0.0 0.0 0.4 0.2 0.0 1.8 0.2 0.0 1.6 5.8 0.0 0.2 0.1 9.2 3.4 0.6 0.2 0.0 0.2 PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 119.8;Endometrial stromal cells: 37.9;Leydig cells: 34.5;Peritubular cells: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.4" "Group enriched" "Detected in many" 7 "dendritic cells: 5.4;granulocytes: 2.5" "Cell line enhanced" "Detected in many" "HHSteC: 16.1;HSkMC: 30.6;hTCEpi: 11.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA048682, HPA053453" Uncertain Approved Nucleoplasm "Secreted - unknown location" NA NA 76000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA048682: AB_2680492, HPA053453: AB_2682155" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" 16.1 6.6 15.7 8.4 17.0 2.3 10.7 12.1 23.5 30.3 15.7 13.4 3.0 20.4 14.9 7.1 23.0 5.6 8.0 14.4 13.3 42.6 3.2 13.4 15.2 14.1 14.6 16.8 4.0 0.4 16.4 4.0 13.1 13.6 4.5 9.5 7.5 7.5 2.1 15.7 17.8 6.3 12.3 29.1 11.3 6.4 14.4 5.1 24.8 1.8 13.6 5.1 9.1 12.3 2.7 2.6 1.0 0.4 1.9 2.3 5.8 0.5 0.0 0.1 0.2 3.4 0.8 0.5 2.7 0.0 0.1 4.3 2.7 2.0 0.3 3.0 3.9 1.2 4.7 0.3 16.1 0.4 2.1 30.6 11.4 0.5 1.7 0.2 0.6 2.5 0.8 0.3 0.0 1.4 0.3 3.0 0.6 0.3 0.8 0.4 0.3 2.8 2.3 0.6 0.3 0.5 6.2 7.0 1.3 7.9 0.2 4.8 0.5 0.7 2.3 0.2 0.3 1.3 0.1 0.3 1.4 1.4 0.6 0.8 0.5 0.3 0.2 0.3 0.1 0.4 0.1 0.2 0.1 0.5 0.2 0.2 2.5 0.3 0.2 5.4 0.3 0.1 15.7 17.0 12.1 23.5 14.4 13.3 14.1 14.6 13.1 12.3 14.4 12.3 0.4 0.0 2.6 119.8 0.3 2.0 0.7 5.1 0.6 1.2 1.8 1.4 1.9 7.2 4.8 5.5 8.4 0.5 5.7 0.4 0.0 4.0 0.3 11.8 37.9 3.4 0.0 0.0 0.3 0.0 1.1 8.3 0.5 16.1 0.0 0.2 3.3 0.1 1.2 0.0 0.9 0.4 2.0 0.3 1.6 1.7 34.5 1.8 1.8 10.3 1.6 15.7 0.0 3.0 0.3 0.4 0.0 44.0 0.2 1.4 0.2 10.2 3.7 3.0 6.6 1.4 1.8 0.6 0.1 0.8 3.0 0.4 0.7 0.1 1.0 0.4 PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 135.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 240.4;Distal enterocytes: 202.4;Hepatocytes: 111.5;Proximal enterocytes: 181.3;Theca cells: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Cell line enhanced" "Detected in many" "BJ: 189.8;fHDF/TERT166: 473.2;HHSteC: 196.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" 33.3 135.2 6.3 26.6 7.0 2.0 20.9 6.2 9.5 17.8 6.2 79.9 29.5 8.5 3.1 10.2 12.4 20.7 11.6 5.8 6.2 23.8 77.0 70.4 11.0 6.9 6.6 27.5 26.1 2.1 3.0 58.5 7.5 6.7 64.3 2.3 16.4 3.4 4.7 3.5 61.8 16.7 6.8 8.5 9.2 11.7 8.0 3.0 21.3 8.7 14.8 16.6 11.5 7.2 19.9 20.0 6.4 0.3 129.4 164.8 0.3 189.8 157.7 110.4 79.9 1.0 4.1 0.1 9.8 473.2 3.5 8.5 13.9 13.3 125.2 0.2 10.0 8.8 13.4 0.1 196.5 0.2 3.8 58.7 0.3 63.7 5.2 135.6 94.2 1.4 0.0 89.4 79.2 74.1 0.1 0.7 7.4 4.8 24.1 0.4 0.1 0.4 117.5 8.7 0.9 1.6 92.5 3.3 1.1 12.6 13.5 5.3 120.0 38.2 22.5 131.5 13.9 0.3 1.0 0.3 18.3 0.2 0.2 0.0 1.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 7.7 0.0 0.0 0.8 6.3 7.0 6.2 9.5 5.8 6.2 6.9 6.6 7.5 6.8 8.0 7.2 49.5 240.4 38.2 3.6 2.6 2.3 0.9 18.0 1.8 0.2 11.5 4.7 4.4 8.6 13.8 9.2 0.0 0.5 0.8 202.4 13.7 6.4 1.2 2.6 18.7 23.2 12.6 5.2 22.2 30.2 0.8 36.1 15.3 11.6 0.0 20.3 36.0 111.5 11.5 0.0 27.6 26.5 4.1 29.8 50.7 0.8 17.4 51.0 1.8 30.0 5.2 1.3 0.0 21.6 1.0 19.4 46.1 5.3 3.1 2.1 181.3 9.8 3.4 0.0 13.1 1.0 20.4 1.2 0.7 1.1 1.3 1.4 1.7 96.4 74.3 1.1 PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Glandular and luminal cells: 179.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 29.0;MCF7: 51.7;T-47d: 48.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013376 Uncertain Supported Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Cytosol "HPA013376: AB_1854972" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-3)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.27e-1)" "prognostic favorable (6.38e-5)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (4.18e-2)" "unprognostic (1.07e-2)" 1.9 1.1 1.6 0.8 2.0 2.3 3.5 3.7 1.8 1.7 8.4 2.5 3.6 1.4 8.2 3.1 3.8 2.5 0.8 2.7 1.8 16.1 4.4 5.4 1.0 1.8 2.1 1.1 4.6 4.3 1.4 3.9 1.6 1.2 2.3 8.9 1.8 1.7 3.9 2.9 3.2 0.8 1.8 1.1 5.7 2.7 2.0 0.9 3.7 0.9 2.1 1.7 1.5 2.4 5.4 6.2 1.7 3.7 1.1 0.4 8.0 0.4 0.6 0.9 0.7 29.0 12.7 2.4 5.4 0.1 3.8 4.3 2.6 3.9 1.5 1.2 1.5 1.3 2.1 11.5 1.2 0.9 1.3 0.1 1.9 0.5 1.6 1.7 0.1 2.3 3.1 1.6 0.1 51.7 2.5 2.3 3.0 9.0 2.3 1.4 1.7 2.3 12.9 5.9 1.1 1.6 4.1 9.6 3.0 7.2 48.8 1.3 0.2 0.5 3.2 0.5 1.0 1.9 1.3 2.0 1.3 0.9 1.1 1.6 0.2 1.5 1.4 0.3 1.5 1.1 1.4 1.4 0.3 1.3 2.2 1.4 1.1 1.6 0.6 1.3 0.9 0.4 1.6 2.0 3.7 1.8 2.7 1.8 1.8 2.1 1.6 1.8 2.0 2.4 0.4 189.1 50.4 2.9 4.5 63.0 58.9 17.0 30.7 14.4 60.3 15.0 4.3 37.1 31.1 90.1 54.2 35.5 4.0 68.6 41.1 26.2 4.0 110.1 14.4 1.7 14.9 0.4 11.5 24.4 15.0 4.7 55.5 179.2 1.3 1.8 1.8 20.1 3.7 5.0 10.6 26.7 22.4 0.8 4.2 2.5 1.8 3.5 16.0 1.9 1.2 12.3 2.1 1.5 4.6 57.5 39.7 0.7 6.3 43.6 29.3 102.0 30.0 62.7 6.6 1.2 4.8 16.6 9.4 34.7 68.3 48.4 6.3 1.5 27.3 102.7 PARVA "FLJ10793, FLJ12254, MXRA2" ENSG00000197702 "Parvin alpha" Q9NVD7 11 12377563-12535356 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cell shape, Chemotaxis, Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 11 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 229.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005964 Approved Supported "Actin filaments,Focal adhesion sites,Cytosol" NA NA 7300000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Actin filaments, Focal adhesion sites" Cytosol "HPA005964: AB_1079569" "unprognostic (3.87e-2)" "unprognostic (7.38e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.76e-4)" "unprognostic (7.37e-3)" "unprognostic (1.38e-2)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (1.76e-2)" "unprognostic (2.80e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-2)" "unprognostic (6.73e-2)" "unprognostic (6.58e-3)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" 61.8 17.6 9.3 22.7 9.0 0.1 40.9 7.2 10.1 53.9 16.5 92.4 17.5 71.8 16.7 42.8 38.8 31.9 34.3 9.8 11.6 23.0 16.9 28.8 6.4 11.0 7.3 31.9 36.0 16.9 11.7 35.9 8.4 50.6 38.4 8.9 20.9 68.9 8.1 14.0 26.1 95.5 11.3 11.3 42.5 6.8 8.6 4.6 17.9 11.7 9.1 55.0 28.2 11.0 34.0 33.1 30.2 39.4 147.8 110.6 69.1 126.5 130.1 87.7 81.6 24.7 51.8 0.0 41.1 229.5 9.9 20.7 0.4 66.4 104.0 0.6 14.9 0.1 42.4 18.7 114.7 0.1 0.9 91.3 22.3 37.1 57.4 107.5 110.9 0.0 0.1 0.3 131.8 20.4 0.0 0.2 14.2 20.2 26.4 0.0 75.2 0.2 44.9 32.8 4.8 0.1 97.6 39.1 65.5 66.9 18.4 0.9 138.2 105.1 43.8 57.2 35.4 0.1 0.1 0.2 58.5 0.1 118.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 9.0 7.2 10.1 9.8 11.6 11.0 7.3 8.4 11.3 8.6 11.0 37.0 99.3 33.0 47.3 1.1 13.8 25.0 29.3 20.5 4.3 24.4 24.8 45.1 18.6 27.0 27.6 0.0 39.9 0.7 39.6 39.2 56.1 0.9 26.9 62.5 33.3 27.1 0.0 31.4 67.1 92.2 59.1 24.5 35.9 5.1 34.8 39.7 19.1 6.5 0.0 34.9 26.2 18.3 1.8 8.8 2.5 41.0 2.0 46.2 36.5 1.0 25.3 0.0 30.7 1.0 51.7 25.4 51.9 0.2 33.5 23.1 38.1 54.8 2.5 52.6 32.6 60.6 1.1 3.4 20.2 8.9 19.0 2.3 25.1 32.4 25.1 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PATL2 Pat1a ENSG00000229474 "PAT1 homolog 2" C9JE40 15 44665732-44711316 "Disease related genes, Human disease related genes, Predicted intracellular proteins" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;lymphoid tissue: 17.2" "Cell type enhanced" "Detected in many" "B-cells: 29.2;dendritic cells: 19.1;NK-cells: 51.5;Plasma cells: 15.7;T-cells: 29.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 21.6;memory CD4 T-cell: 6.0;memory CD8 T-cell: 17.7;naive CD8 T-cell: 12.8" "Lineage enriched" "Detected in many" 6 "T-cells: 21.6" "Cell line enriched" "Detected in some" 28 "U-266/70: 124.9" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.28e-2)" "unprognostic (8.59e-3)" "unprognostic (3.30e-3)" "unprognostic (5.55e-2)" "unprognostic (7.28e-2)" "unprognostic (1.11e-2)" "unprognostic (3.00e-3)" "unprognostic (7.82e-2)" "unprognostic (3.69e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-2)" "unprognostic (9.48e-2)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (9.69e-4)" 0.9 1.1 0.8 7.7 1.1 7.7 1.3 0.6 0.8 0.3 1.5 2.1 2.4 1.1 1.7 0.6 1.4 2.3 0.7 0.7 0.8 0.5 1.7 3.9 17.2 1.8 1.1 0.9 0.6 0.4 0.2 1.0 1.1 0.8 2.5 0.1 2.5 0.6 0.3 2.7 3.2 0.8 0.9 13.9 3.2 0.5 1.2 3.6 0.7 0.0 10.8 2.1 0.2 1.4 0.2 0.0 0.0 0.1 0.0 1.1 2.8 0.1 0.4 0.9 0.9 0.6 1.2 0.9 0.1 0.3 1.8 1.3 0.1 0.2 0.5 2.1 0.0 1.2 0.0 0.1 0.5 0.5 0.7 1.2 0.1 0.5 0.3 0.2 0.0 1.4 0.2 4.5 0.3 0.3 0.1 1.4 0.4 0.1 0.1 1.8 0.0 0.5 0.1 0.4 0.1 0.0 0.0 1.3 0.1 0.2 0.1 0.9 0.6 0.3 0.0 0.8 0.0 124.9 4.3 0.4 1.2 3.1 0.4 1.5 0.3 2.6 21.6 0.7 3.2 3.3 6.0 17.7 0.7 3.5 3.6 12.8 1.6 2.7 0.5 0.6 0.9 3.7 0.8 1.1 0.6 0.8 0.7 0.8 1.8 1.1 1.1 0.9 1.2 1.4 1.4 3.2 1.7 1.6 29.2 0.9 0.6 0.5 0.6 0.0 0.6 0.6 11.7 0.0 0.4 0.0 0.0 0.2 19.1 2.0 0.0 0.4 0.3 2.4 1.0 1.8 0.0 3.0 0.3 0.6 0.5 1.9 8.2 0.8 0.0 1.2 1.4 1.0 2.0 0.0 0.4 1.4 0.0 4.8 2.3 0.0 0.3 5.6 0.0 3.7 5.2 0.0 51.5 0.5 1.3 0.4 0.3 0.0 15.7 0.6 2.2 0.4 8.5 0.0 0.0 1.0 2.6 0.1 0.4 1.4 0.9 0.3 29.8 1.8 0.9 1.3 PCDH12 VE-cadherin-2 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.2" "Group enriched" "Detected in some" 4 "Adipocytes: 38.5;Endothelial cells: 40.0;Hepatic stellate cells: 41.0;Hofbauer cells: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.6" "Lineage enriched" "Detected in single" 41 "monocytes: 4.6" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 25.9;Karpas-707: 66.5;U-937: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" NA NA 14000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" 13.4 5.0 0.8 2.5 0.9 0.5 4.9 2.5 1.7 2.7 1.2 2.0 2.0 2.8 0.4 2.1 2.1 4.0 10.8 0.6 0.8 6.0 4.0 15.5 2.6 0.5 0.3 1.7 1.4 2.9 3.6 30.2 0.6 1.9 1.3 1.6 1.4 2.3 4.0 1.7 2.1 5.2 0.3 18.6 2.0 1.1 1.4 0.8 6.5 5.1 1.0 3.2 1.9 0.3 0.1 0.1 1.9 0.5 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.1 5.0 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.6 1.4 0.2 0.1 0.2 0.5 0.2 0.0 0.0 0.4 0.0 0.4 25.9 0.3 0.0 66.5 0.0 0.4 0.1 0.3 0.5 0.0 0.3 0.5 0.2 3.0 0.0 0.1 0.3 0.7 0.1 0.1 0.3 0.2 0.0 1.8 1.8 0.6 0.1 0.9 0.1 0.4 0.4 0.1 0.4 11.7 2.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.8 0.9 2.5 1.7 0.6 0.8 0.5 0.3 0.6 0.3 1.4 0.3 38.5 0.0 1.1 0.0 0.5 0.6 0.0 0.0 1.2 1.3 0.1 0.1 4.0 0.0 0.0 0.0 2.1 0.3 0.3 0.0 3.9 0.1 1.7 0.1 0.1 40.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.1 1.3 0.0 41.0 0.5 34.6 0.0 0.2 0.0 0.0 8.5 0.3 2.5 0.0 1.5 1.8 6.5 0.3 0.5 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.4 0.0 0.4 0.0 0.7 1.0 0.0 0.2 0.2 0.3 0.5 0.2 1.4 0.0 0.2 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 72.3;Fibroblasts: 56.3;Leydig cells: 37.9;Peritubular cells: 58.6;Sertoli cells: 19.7;Smooth muscle cells: 25.5;Theca cells: 18.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 148.2;ASC diff: 175.0;ASC TERT1: 190.8;BJ hTERT+: 86.8;fHDF/TERT166: 143.3;HHSteC: 129.4;HSkMC: 195.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 5900000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Golgi apparatus" "HPA017976: AB_1855045" "unprognostic (2.77e-1)" "unprognostic (1.86e-2)" "unprognostic (3.73e-3)" "unprognostic (9.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.39e-2)" "unprognostic (2.36e-1)" "unprognostic (4.30e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-2)" "unprognostic (8.76e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-2)" "unprognostic (6.27e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (4.71e-4)" 22.2 5.2 2.6 7.9 3.0 0.1 13.5 2.8 3.2 25.3 2.6 12.2 9.3 30.4 11.2 6.4 11.7 22.5 6.5 2.5 4.8 7.1 2.1 7.2 1.7 4.1 5.8 21.0 1.5 2.0 2.4 44.2 3.8 17.5 13.8 2.1 6.5 13.5 2.6 4.1 8.7 18.4 3.2 6.4 6.7 4.5 3.9 3.6 5.1 23.2 1.4 10.8 8.4 3.0 0.0 0.3 148.2 0.0 175.0 190.8 0.1 27.4 86.8 5.0 7.7 0.3 0.0 0.0 0.1 143.3 0.4 0.4 34.2 0.7 2.6 0.2 1.0 0.0 0.0 0.0 129.4 0.0 0.1 195.9 0.3 9.4 3.8 4.7 1.0 0.7 0.0 0.6 2.8 0.0 3.9 0.1 0.3 0.0 2.7 11.7 4.1 0.0 0.0 0.1 0.0 9.6 0.0 0.0 0.2 38.3 0.9 0.0 0.0 69.3 4.2 13.9 0.5 0.2 0.0 0.0 3.9 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.0 2.8 3.2 2.5 4.8 4.1 5.8 3.8 3.2 3.9 3.0 3.4 0.0 0.5 1.3 0.0 4.1 0.4 0.1 2.2 2.5 1.1 1.7 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.6 1.9 72.3 3.0 0.0 0.0 0.2 0.0 0.3 56.3 0.0 1.7 0.0 6.4 2.5 0.0 3.1 0.0 9.0 0.0 0.0 0.0 7.8 1.3 37.9 0.9 1.8 10.3 0.0 6.8 0.0 0.0 0.6 0.0 0.0 58.6 0.1 0.0 0.0 0.1 0.0 0.2 19.7 6.6 25.5 0.6 0.1 1.2 2.6 0.8 0.7 18.5 0.0 0.1 PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720415-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Group enriched" "Detected in many" 8 "Astrocytes: 311.8;Excitatory neurons: 1152.0;Inhibitory neurons: 882.3;Oligodendrocyte precursor cells: 917.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 43.4;RH-30: 120.4;RT4: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" 1.8 3.2 10.5 5.2 14.6 0.0 3.0 0.0 33.7 23.9 0.0 19.2 3.2 16.9 25.1 14.3 9.7 8.1 19.1 23.7 50.1 2.0 1.0 2.9 1.4 13.0 14.3 4.7 0.9 1.1 0.2 0.2 14.3 10.6 7.8 3.4 0.8 18.2 0.6 11.6 5.0 22.1 3.9 18.6 11.4 1.0 46.3 1.4 4.1 0.4 1.2 16.3 5.9 11.8 0.0 1.1 14.4 20.1 29.5 28.5 0.0 3.8 0.0 1.9 0.9 1.9 26.5 0.0 0.1 0.2 0.0 15.3 1.3 38.5 3.4 0.0 43.4 0.1 26.8 0.0 30.4 0.6 0.0 17.2 8.8 1.0 10.7 17.5 7.5 0.0 0.0 0.0 9.0 0.1 0.0 0.1 8.8 9.3 4.0 0.0 120.4 0.0 0.9 65.2 0.9 0.2 0.4 1.2 1.3 8.2 1.8 6.9 0.0 24.1 6.2 6.7 0.0 0.0 0.0 0.0 18.8 0.1 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 14.6 0.0 33.7 23.7 50.1 13.0 14.3 14.3 3.9 46.3 11.8 1.1 0.0 0.0 311.8 0.3 85.0 92.4 25.7 46.7 46.8 0.7 9.0 83.2 0.0 13.7 64.4 0.0 0.1 0.0 0.3 0.0 0.6 16.9 66.8 8.4 7.6 0.0 0.0 1152.0 0.7 0.1 24.0 20.9 60.4 1.3 0.8 19.2 0.1 0.3 10.1 882.3 0.5 4.1 1.0 3.5 10.4 0.3 1.3 21.4 43.1 0.0 1.3 0.0 917.3 26.4 26.5 0.0 28.6 1.3 26.1 0.0 0.2 27.0 3.4 0.0 51.3 11.0 1.1 2.7 18.5 38.6 0.1 1.8 1.7 0.3 50.3 PCDH9 ENSG00000184226 "Protocadherin 9" Q9HC56 13 66302834-67230445 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 159.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4339.5;Excitatory neurons: 5259.8;Inhibitory neurons: 2489.4;Oligodendrocyte precursor cells: 6313.8;Oligodendrocytes: 14117.8" "Cancer enriched" "Detected in single" 8 "glioma: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 4.5;memory B-cell: 5.3;naive B-cell: 17.3" "Group enriched" "Detected in many" 9 "B-cells: 17.3;granulocytes: 4.5" "Cell line enhanced" "Detected in many" "AF22: 25.1;LHCN-M2: 41.6;TIME: 48.9;U-698: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015581 Approved Nucleoplasm,Centrosome NA NA 2900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Centrosome" "HPA015581: AB_1855048" "unprognostic (1.77e-1)" "unprognostic (8.36e-2)" "unprognostic (9.12e-3)" "unprognostic (4.42e-5)" "unprognostic (7.54e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-1)" "unprognostic (1.38e-1)" "unprognostic (2.35e-1)" "unprognostic (8.21e-2)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (8.47e-4)" "unprognostic (6.44e-3)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (4.35e-4)" 3.8 2.2 37.1 0.4 84.0 3.3 1.0 41.5 53.2 0.9 0.0 1.2 0.2 0.2 1.2 0.3 0.4 1.5 4.9 37.8 51.3 2.5 1.5 1.5 0.7 49.9 52.1 0.6 1.3 0.0 2.0 0.0 56.8 1.6 0.5 9.4 0.3 4.2 1.3 0.2 0.5 0.5 27.1 0.9 1.9 0.9 76.1 2.2 1.0 1.1 0.6 0.7 1.0 159.3 0.0 19.3 25.1 0.0 6.6 5.1 0.0 3.8 0.2 2.7 1.0 0.1 0.1 5.7 0.1 2.9 0.9 0.0 2.1 0.6 1.2 0.0 10.1 0.3 0.2 0.0 6.3 0.7 0.3 12.1 0.7 3.1 5.0 0.6 2.1 2.2 0.6 0.3 41.6 1.6 12.2 0.0 0.2 0.5 2.5 18.2 0.8 0.0 0.5 0.0 3.2 1.3 0.0 0.1 0.3 0.6 0.0 0.1 48.9 1.4 1.2 5.9 2.0 7.3 0.0 64.2 10.6 0.0 5.0 4.5 0.0 0.1 0.0 0.0 0.0 5.3 0.0 0.0 0.0 17.3 0.1 0.1 0.1 0.9 0.0 1.2 0.0 0.2 37.1 84.0 41.5 53.2 37.8 51.3 49.9 52.1 56.8 27.1 76.1 159.3 5.6 19.2 68.0 4339.5 29.1 1.9 2.5 0.0 1.8 318.8 9.2 14.7 152.5 0.0 4.4 5.5 20.9 0.2 4.3 0.9 9.8 1.9 3.6 0.3 6.4 4.7 62.4 2.5 5259.8 0.0 0.2 76.3 11.7 0.3 1.3 1.0 19.2 8.6 0.3 198.5 2489.4 1.4 0.0 1.9 1.4 3.0 29.5 3.7 10.6 237.0 0.3 87.8 2.1 6313.8 14117.8 0.3 1.2 14.7 1.4 2.0 0.0 0.8 0.0 27.1 6.6 27.9 25.4 6.8 5.4 1.2 0.3 0.0 2.7 3.7 0.8 0.8 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 4.9;Endometrial stromal cells: 3.5;Fibroblasts: 4.8;Peritubular cells: 3.4;Sertoli cells: 6.6;Skeletal myocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.6;EFO-21: 8.9;U-2 OS: 3.0" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" 1.3 0.6 0.2 0.5 0.5 0.2 0.9 0.9 1.2 1.2 0.0 1.0 0.2 1.5 0.5 0.7 0.9 0.9 0.8 0.5 0.0 0.7 0.2 0.8 0.1 0.3 0.3 1.6 2.6 2.6 0.7 0.6 0.1 0.9 0.3 0.6 0.8 1.0 0.4 0.8 0.4 1.2 0.4 0.6 0.6 0.4 0.0 0.3 0.6 0.6 0.1 0.9 0.6 0.4 0.0 0.1 1.8 5.6 0.1 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.9 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.0 0.0 0.2 2.2 0.3 1.3 0.1 0.7 0.3 1.3 0.0 0.3 0.1 3.0 2.4 0.0 0.1 0.0 0.0 1.4 0.1 1.5 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.9 1.2 0.5 0.0 0.3 0.3 0.1 0.4 0.0 0.4 1.9 3.2 0.5 0.0 0.0 0.0 0.7 0.0 0.0 4.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 3.5 1.9 2.4 0.0 0.0 1.8 0.0 4.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 3.4 0.1 0.9 0.0 0.9 0.0 0.2 6.6 4.1 1.7 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.7 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PCSK4 "DKFZp434B217, MGC34749, PC4, SPC5" ENSG00000115257 "Proprotein convertase subtilisin/kexin type 4" Q6UW60 19 1481428-1490752 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 66.0" "Group enriched" "Detected in many" 4 "Early spermatids: 277.1;Late spermatids: 679.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.7;HMC-1: 3.7;JURKAT: 5.3;U-266/70: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA005572 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA005572: AB_1855087" "unprognostic (1.00e-2)" "unprognostic (9.12e-2)" "unprognostic (2.36e-3)" "prognostic favorable (9.45e-5)" "unprognostic (5.23e-2)" "unprognostic (6.14e-2)" "unprognostic (1.78e-1)" "unprognostic (6.34e-3)" "unprognostic (2.94e-1)" "unprognostic (8.29e-3)" "unprognostic (1.93e-2)" "unprognostic (7.44e-2)" "unprognostic (6.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.71e-2)" "unprognostic (3.57e-2)" "unprognostic (7.03e-2)" 0.8 1.4 1.1 0.3 1.1 0.6 1.2 0.9 2.5 1.7 1.3 1.3 1.7 1.1 0.1 1.1 3.2 0.6 0.5 1.4 1.6 3.7 4.0 1.1 0.3 1.9 2.8 1.1 2.8 0.9 7.1 0.2 1.5 1.8 0.1 0.6 1.1 1.2 0.3 0.6 1.1 0.1 1.8 0.7 1.4 66.0 1.6 0.4 3.4 0.0 0.1 1.0 1.2 0.9 0.6 0.3 1.2 6.7 0.1 0.2 1.8 0.5 0.1 0.0 0.2 0.6 1.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.3 1.1 1.0 0.4 0.0 3.7 0.6 0.0 0.0 0.1 0.3 0.2 5.3 1.2 1.8 0.0 0.0 0.1 0.3 0.1 0.3 0.4 1.2 0.1 0.1 0.4 0.0 0.0 1.4 0.1 0.3 0.1 0.4 2.5 0.4 0.0 0.5 0.0 0.1 0.0 7.7 1.5 0.3 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 1.1 0.9 2.5 1.4 1.6 1.9 2.8 1.5 1.8 1.6 0.9 0.2 0.0 1.1 12.1 0.1 0.6 0.9 1.8 0.6 1.5 3.1 2.2 2.3 1.5 3.6 0.0 8.4 0.5 1.7 1.6 5.9 1.8 277.1 5.2 1.0 0.5 0.0 1.7 3.2 1.0 0.5 0.8 3.1 1.1 0.0 3.3 0.0 3.2 0.8 3.3 3.7 1.4 0.0 0.3 0.0 679.2 6.2 1.1 3.6 3.7 0.0 2.4 0.0 1.0 1.6 0.9 1.1 5.3 1.4 0.5 2.8 1.9 8.3 9.1 0.0 0.2 0.5 98.0 9.6 1.2 0.0 0.3 0.7 2.4 2.1 0.7 PCYT1B "CCT-beta, CTB" ENSG00000102230 "Phosphate cytidylyltransferase 1, choline, beta" Q9Y5K3 X 24558087-24672677 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.2;retina: 12.1;testis: 13.4" "Cell type enhanced" "Detected in some" "Astrocytes: 23.5;Early spermatids: 29.1;Late spermatids: 90.1;Muller glia cells: 30.1;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 41.9" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 10.3;CACO-2: 22.2;HEL: 25.7;Hep G2: 10.2;NTERA-2: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006367 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 31: Spermatids - Spermatogenesis" "HPA006367: AB_1079585" "unprognostic (4.49e-1)" "unprognostic (2.20e-1)" "unprognostic (1.16e-1)" "unprognostic (7.39e-2)" "unprognostic (9.88e-2)" "unprognostic (6.83e-2)" "unprognostic (5.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (5.64e-2)" "unprognostic (2.63e-6)" "unprognostic (2.62e-4)" "unprognostic (4.56e-2)" "unprognostic (1.75e-2)" "unprognostic (1.96e-4)" 0.1 0.8 12.1 0.2 12.2 0.8 0.1 10.6 12.8 0.7 7.5 1.2 0.3 1.6 0.6 0.8 2.2 0.4 2.9 13.2 9.8 0.2 0.0 0.7 0.0 9.5 10.2 1.4 1.5 0.0 1.3 1.3 9.8 0.8 0.2 12.1 0.1 2.4 0.0 0.1 0.6 2.5 8.6 0.2 0.2 13.4 11.4 0.5 0.0 0.0 0.0 0.3 0.3 12.9 0.0 0.0 10.3 0.1 0.0 0.0 0.1 0.0 0.9 0.3 0.1 22.2 0.0 0.0 5.2 0.0 0.0 1.0 4.2 0.0 0.0 0.0 0.1 25.7 0.0 10.2 0.1 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 3.9 0.5 11.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 7.2 5.8 0.0 0.0 0.5 7.1 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 4.4 0.7 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 12.1 12.2 10.6 12.8 13.2 9.8 9.5 10.2 9.8 8.6 11.4 12.9 0.0 0.0 0.0 23.5 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.5 1.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.8 29.1 10.7 0.2 0.1 1.8 1.3 5.6 0.0 0.0 0.4 0.0 0.2 4.5 5.8 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 90.1 0.3 0.9 0.0 3.7 0.3 30.1 0.0 23.6 41.9 0.2 0.0 2.6 0.1 0.1 0.0 0.5 6.4 1.6 0.0 0.0 1.0 1.8 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.1 PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 17.9;Langerhans cells: 13.1;Microglial cells: 12.2;monocytes: 26.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 71.4;BJ hTERT+: 111.6;HDLM-2: 88.1;TIME: 49.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" NA NA 31000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" 4.4 0.8 0.4 6.9 0.6 0.3 4.3 0.5 0.5 2.5 0.3 1.7 0.7 2.2 1.2 2.0 2.4 3.4 2.7 0.4 0.8 1.2 4.2 7.1 10.4 1.1 0.6 1.6 0.6 0.4 0.2 4.8 1.1 1.0 2.1 0.0 1.3 1.4 1.5 1.4 1.5 3.1 0.9 15.1 1.4 0.6 0.7 5.0 1.0 2.2 6.2 4.2 2.2 1.3 6.0 0.0 0.0 0.0 4.7 5.4 0.1 71.4 111.6 33.7 40.4 0.0 0.3 0.0 0.2 29.2 4.8 0.5 0.1 9.7 33.3 88.1 0.0 0.0 0.0 0.0 26.5 0.0 0.0 5.0 0.1 15.8 18.5 9.7 22.4 0.0 0.0 8.5 41.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.7 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.0 0.1 49.7 24.0 1.4 11.8 20.1 1.2 0.1 0.1 13.6 0.0 3.0 1.5 0.3 0.0 0.5 1.4 0.6 0.2 0.7 0.3 0.3 0.1 0.0 0.3 0.7 0.0 0.1 0.0 1.1 0.3 0.4 0.6 0.5 0.5 0.4 0.8 1.1 0.6 1.1 0.9 0.7 1.3 6.1 6.4 0.5 1.6 0.4 1.0 0.1 0.7 1.8 0.0 0.2 1.5 0.1 0.0 0.7 0.0 0.0 0.6 0.4 0.0 0.0 0.1 0.0 0.0 0.4 2.2 0.0 0.0 1.6 0.2 17.9 6.7 0.5 0.0 3.8 0.2 6.8 0.0 2.9 0.0 1.4 0.0 0.0 5.3 13.1 0.0 5.9 2.5 1.8 12.2 26.4 0.0 0.0 1.0 2.4 3.7 0.0 2.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 2.2 3.1 0.0 0.0 0.3 1.0 0.8 1.1 0.1 0.0 0.1 PDE1B PDES1B ENSG00000123360 "Phosphodiesterase 1B" Q01064 12 54549601-54579239 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 76.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.6;Inhibitory neurons: 10.2;Kupffer cells: 13.0;Macrophages: 9.4;Sertoli cells: 13.1;Smooth muscle cells: 13.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "basal ganglia: 76.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 12.7;HMC-1: 14.9;NB-4: 10.7;THP-1: 9.0;U-937: 7.2" "Region enriched" "Detected in all" 6 "basal ganglia: 999.4" "Region enriched" "Detected in all" 7 "basal ganglia: 228.7" HPA018492 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA018492: AB_1855119" "unprognostic (2.90e-1)" "unprognostic (1.51e-1)" "unprognostic (7.67e-4)" "unprognostic (5.63e-3)" "unprognostic (7.02e-2)" "unprognostic (7.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.39e-2)" "unprognostic (1.14e-1)" "unprognostic (5.11e-2)" "unprognostic (3.84e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (6.64e-4)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (2.83e-2)" 9.1 1.1 8.4 4.0 76.9 4.8 4.6 0.0 13.7 2.0 0.0 7.4 1.0 2.7 1.8 1.7 2.0 2.2 1.4 6.3 0.1 0.8 1.0 2.3 1.3 0.0 0.0 8.6 0.4 6.1 0.3 0.2 0.0 1.3 1.0 0.4 1.0 1.4 0.6 1.4 3.4 4.0 0.0 4.0 3.3 0.7 2.4 0.9 2.0 1.0 0.8 8.7 1.5 4.9 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 2.1 0.0 0.0 12.7 0.6 4.3 0.0 0.0 0.0 5.5 14.9 0.7 0.0 0.0 0.0 0.0 0.0 5.5 0.0 2.3 0.0 0.0 0.5 10.7 3.5 0.0 0.0 2.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 2.5 0.0 7.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 76.9 0.0 13.7 6.3 0.1 0.0 0.0 0.0 0.0 2.4 4.9 2.3 0.0 1.1 1.6 1.8 1.0 0.2 0.0 0.6 2.7 0.2 0.6 3.6 0.0 0.6 3.7 0.0 0.1 1.4 0.0 0.0 0.0 6.3 0.1 0.0 0.8 1.8 3.6 18.6 0.0 0.0 1.5 0.0 0.0 0.0 4.4 0.0 0.3 8.5 5.0 10.2 0.0 0.0 13.0 2.5 4.9 2.1 9.4 0.0 2.8 6.7 0.1 4.1 1.0 0.9 0.0 0.0 3.0 2.6 0.4 0.0 0.0 0.0 0.2 13.1 0.6 13.7 0.8 0.6 0.2 0.4 0.3 2.8 0.4 0.1 0.1 PDE1C Hcam3 ENSG00000154678 "Phosphodiesterase 1C" Q14123 7 31751179-32428131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 68.9;heart muscle: 58.5" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 1071.4" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 44.4;fHDF/TERT166: 148.3;hTERT-RPE1: 44.9;U-251 MG: 77.9;WM-115: 105.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052375 Approved Nucleoplasm NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA052375: AB_2681802" "unprognostic (1.29e-2)" "unprognostic (2.20e-5)" "unprognostic (1.68e-2)" "unprognostic (1.20e-3)" "unprognostic (2.29e-1)" "unprognostic (5.65e-2)" "unprognostic (4.06e-3)" "unprognostic (2.75e-1)" "unprognostic (6.79e-3)" "unprognostic (6.49e-2)" "unprognostic (3.88e-5)" "unprognostic (7.03e-2)" "unprognostic (3.09e-3)" "unprognostic (5.76e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.06e-3)" 2.4 1.8 19.2 2.5 43.0 0.0 4.3 21.4 39.9 0.7 0.0 3.0 1.4 2.4 6.0 6.4 10.5 1.5 58.5 18.9 24.2 4.2 0.1 4.9 0.6 29.4 27.9 3.8 2.6 0.3 1.3 3.2 27.7 2.0 1.8 7.4 1.8 3.2 0.6 0.4 3.3 5.0 16.4 0.6 4.0 3.8 28.6 1.6 3.1 4.0 0.1 9.8 1.4 68.9 0.3 5.8 15.5 0.0 0.6 0.4 0.2 44.4 18.3 20.8 17.1 0.0 0.0 0.0 0.2 148.3 0.0 1.2 0.0 0.0 27.1 0.0 0.0 1.3 1.4 0.0 0.1 0.0 31.9 1.9 0.0 4.3 0.2 44.9 7.1 0.0 0.1 0.1 1.7 0.0 0.1 0.0 0.0 0.0 13.7 0.0 0.0 0.0 22.5 0.0 6.8 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.2 22.8 8.6 0.4 77.9 0.4 0.0 0.0 2.4 0.5 105.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 43.0 21.4 39.9 18.9 24.2 29.4 27.9 27.7 16.4 28.6 68.9 1.2 0.0 0.0 7.5 0.1 0.0 0.7 0.1 1.2 69.5 2.8 17.1 136.0 0.0 0.7 1.8 52.1 0.0 0.1 0.0 0.0 4.8 53.4 0.2 0.1 3.9 0.0 0.0 70.8 0.4 0.0 8.7 0.0 0.4 8.8 0.2 0.0 0.0 0.1 3.3 169.2 0.0 59.0 0.0 0.2 50.3 0.3 0.5 0.0 15.9 0.0 0.9 0.0 196.6 1071.4 0.2 0.0 0.4 0.1 0.2 0.0 0.0 2.2 4.7 0.0 0.9 9.4 1.3 1.2 0.2 0.0 0.0 0.1 1.2 0.0 0.0 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDHB PDHE1B ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 299.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 300.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033794, HPA036744, HPA036745" Enhanced Supported Nucleoplasm,Mitochondria No No 61000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "CAB033794: AB_2162946, HPA036744: AB_10670921, HPA036745: AB_2675285" "unprognostic (2.06e-2)" "unprognostic (1.79e-1)" "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (7.22e-2)" "unprognostic (1.42e-1)" "unprognostic (3.20e-2)" "unprognostic (6.13e-2)" "unprognostic (9.62e-2)" "unprognostic (5.94e-2)" "unprognostic (3.98e-1)" "unprognostic (2.35e-1)" "prognostic favorable (2.79e-8)" "unprognostic (2.67e-1)" "unprognostic (8.37e-2)" "unprognostic (1.06e-2)" "unprognostic (9.85e-2)" 59.9 76.5 48.7 42.2 50.2 25.7 42.9 53.9 62.7 43.3 63.6 56.8 42.5 38.5 44.6 57.4 37.7 35.9 175.0 49.7 52.3 100.8 110.7 36.4 53.1 51.7 49.4 26.5 36.4 88.8 44.1 57.0 51.5 48.5 60.4 30.7 45.9 52.1 272.6 36.8 37.6 63.8 51.6 42.8 53.9 42.3 53.1 53.1 40.8 299.4 56.0 49.7 35.9 54.3 66.5 90.9 92.3 69.8 91.7 111.1 110.4 81.6 101.3 117.9 120.6 165.1 62.6 140.3 44.9 103.8 109.0 37.6 113.2 74.9 90.0 81.7 83.0 125.4 163.7 126.0 92.5 103.0 67.9 97.9 67.7 95.5 55.8 137.5 103.1 114.2 65.9 61.5 129.5 63.1 98.2 107.8 127.2 69.2 101.3 46.3 71.8 136.1 188.1 89.1 63.7 70.2 75.6 107.2 85.4 131.3 159.0 108.7 76.3 62.9 83.7 66.8 94.2 85.2 129.9 99.2 96.2 120.8 60.7 57.8 98.9 98.7 83.2 115.1 87.9 102.2 81.7 80.5 141.1 103.4 90.9 82.4 19.6 129.4 109.7 94.7 113.2 124.1 48.7 50.2 53.9 62.7 49.7 52.3 51.7 49.4 51.5 51.6 53.1 54.3 57.8 60.9 34.5 5.9 45.3 27.9 40.7 142.0 26.7 31.8 29.4 31.6 300.6 48.6 96.0 35.0 25.0 174.1 35.3 41.0 230.9 95.9 76.3 37.0 37.3 58.0 58.0 22.5 10.9 72.2 101.6 54.1 29.6 34.2 39.3 48.5 46.1 76.1 84.6 57.2 13.3 50.4 162.8 37.9 26.6 16.9 60.3 37.2 56.9 9.4 76.5 61.7 70.0 9.0 13.6 55.9 43.0 51.1 38.8 19.1 45.8 146.8 70.7 45.9 65.7 30.8 72.3 98.2 88.3 42.8 29.8 157.2 44.7 224.4 53.0 37.7 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA053136: , HPA060510: AB_2684298" "unprognostic (1.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.88e-2)" "unprognostic (9.28e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.29e-4)" "unprognostic (2.47e-2)" "unprognostic (2.17e-2)" "unprognostic (3.59e-3)" "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" 12.2 3.3 4.7 5.0 5.2 8.4 14.2 7.2 5.8 11.9 2.4 7.6 5.1 10.2 5.7 13.6 7.9 12.3 5.7 5.7 5.1 3.9 12.4 7.1 4.7 5.2 5.7 7.8 14.4 4.2 9.0 2.9 4.4 9.3 6.2 5.1 14.1 8.9 11.4 17.0 8.0 4.9 5.4 4.8 13.4 11.8 4.7 4.1 8.8 7.6 6.2 8.7 8.2 4.7 1.6 11.7 2.4 4.2 0.1 1.2 8.2 1.1 4.1 1.5 1.4 1.8 5.8 10.3 1.2 2.7 1.5 8.6 2.4 3.5 2.2 2.9 1.7 9.1 6.2 8.2 2.0 13.8 9.2 1.6 8.3 1.8 6.1 1.5 0.8 4.2 4.5 6.3 1.3 7.7 6.9 15.2 3.5 7.6 2.3 16.5 5.5 3.3 1.5 3.3 9.7 1.2 2.9 6.3 1.8 0.7 5.9 8.5 2.1 3.6 4.2 2.8 4.1 7.1 1.8 12.3 6.7 5.9 4.5 2.1 1.2 0.3 1.0 2.2 1.6 1.5 1.6 1.2 1.4 1.5 1.5 1.6 1.0 1.2 2.1 1.8 1.2 0.3 4.7 5.2 7.2 5.8 5.7 5.1 5.2 5.7 4.4 5.4 4.7 4.7 24.9 16.0 30.1 18.6 9.9 73.9 61.7 21.3 38.1 20.6 67.8 33.8 5.7 31.5 46.9 27.6 2.1 9.2 27.0 22.5 7.9 7.5 9.6 69.7 30.1 15.6 24.6 6.9 20.9 10.4 6.3 39.8 52.5 86.1 9.5 3.3 11.4 35.8 3.9 11.8 13.9 35.1 18.3 10.1 25.3 4.7 11.1 12.4 24.9 5.6 5.3 13.5 2.1 9.0 7.2 7.6 35.3 18.4 10.9 15.0 10.9 5.5 44.2 7.8 6.6 110.1 32.2 31.3 17.0 38.4 85.4 13.0 13.6 3.7 36.9 33.9 PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 277.0" "Cell type enhanced" "Detected in many" "Early spermatids: 459.8;Late spermatids: 516.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1900000 "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Cytosol "HPA018257: AB_10960391, HPA056484: AB_2683147" "unprognostic (1.16e-1)" "unprognostic (2.41e-3)" "unprognostic (5.79e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.55e-4)" "prognostic unfavorable (8.72e-6)" "unprognostic (1.36e-3)" "unprognostic (2.38e-1)" "unprognostic (8.51e-2)" "unprognostic (2.37e-2)" "unprognostic (8.82e-2)" "unprognostic (6.02e-3)" "unprognostic (2.60e-2)" "unprognostic (9.74e-2)" "unprognostic (2.06e-1)" "unprognostic (4.54e-3)" 35.0 11.5 41.6 41.5 39.3 14.4 23.5 13.8 49.9 26.3 61.7 43.8 48.8 55.5 5.6 67.1 34.9 34.1 128.6 60.4 65.0 44.6 4.7 19.1 32.5 30.7 50.9 19.1 15.9 15.2 29.9 15.5 58.0 35.6 30.7 277.0 39.8 62.0 70.4 40.3 59.6 44.1 8.3 19.1 36.8 141.1 47.0 29.7 38.5 21.0 21.2 64.7 42.8 31.7 314.8 420.2 25.9 0.6 26.8 56.9 336.9 187.2 66.6 186.2 222.8 444.5 320.4 37.0 147.8 134.9 174.9 243.0 141.7 292.3 173.1 102.1 111.0 132.0 189.1 24.2 65.2 53.7 203.4 27.0 61.2 190.0 96.0 273.7 367.8 153.7 37.0 1.3 195.7 239.8 182.5 44.4 42.9 133.9 149.3 138.8 46.9 150.1 185.7 115.9 69.5 64.7 133.7 111.0 172.0 307.8 93.7 80.3 449.2 124.6 65.3 380.5 199.3 195.4 200.1 135.7 331.0 98.0 78.5 30.8 8.5 2.9 26.8 4.2 21.2 13.7 26.2 25.0 14.5 15.3 9.6 15.4 1.3 26.7 1.6 22.5 37.6 16.5 41.6 39.3 13.8 49.9 60.4 65.0 30.7 50.9 58.0 8.3 47.0 31.7 30.5 3.2 7.0 128.6 14.8 28.7 58.5 96.8 14.8 40.4 10.3 7.7 147.4 8.6 57.9 64.4 54.2 7.8 16.3 72.6 43.0 115.7 459.8 41.2 9.0 36.0 37.2 10.3 49.4 10.8 205.8 25.9 35.7 63.8 55.9 25.8 14.6 0.7 33.9 42.1 25.9 23.1 124.1 7.6 31.4 516.3 7.5 14.3 19.6 15.0 15.4 113.1 16.5 16.1 6.7 116.8 57.2 6.8 14.2 80.9 53.2 5.9 62.6 133.4 13.1 43.2 34.6 149.4 3.5 25.1 22.6 26.5 28.8 11.2 28.9 64.2 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PHKG2 ENSG00000156873 "Phosphorylase kinase catalytic subunit gamma 2" P15735 16 30748293-30761176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 130.1" "Group enriched" "Detected in many" 5 "Early spermatids: 397.0;Late spermatids: 1576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065618, HPA068751" Supported Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA065618: AB_2685520, HPA068751: AB_2686025" "unprognostic (7.63e-3)" "prognostic favorable (7.90e-4)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.81e-2)" "unprognostic (3.72e-2)" "prognostic favorable (1.90e-4)" "unprognostic (6.45e-2)" "unprognostic (1.25e-2)" "prognostic favorable (8.02e-4)" "unprognostic (6.15e-2)" "unprognostic (5.27e-2)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" 9.0 15.8 17.5 11.5 16.9 30.0 9.9 17.1 18.7 10.0 15.9 12.9 11.0 10.1 9.5 10.2 11.7 8.2 12.1 18.9 16.4 14.7 19.1 10.0 12.5 17.7 17.2 8.3 9.7 18.9 15.9 7.8 18.8 14.7 12.0 8.9 11.5 12.0 13.2 14.6 12.0 9.9 16.0 12.9 13.8 130.1 17.5 11.6 13.6 8.8 12.7 10.1 9.2 16.2 24.7 16.3 13.1 16.2 11.8 9.4 29.8 17.2 24.6 22.1 25.1 13.5 12.6 21.0 19.3 17.1 11.5 24.0 13.5 21.5 17.6 11.4 38.2 11.9 28.8 38.7 18.1 18.1 16.9 12.9 11.2 21.4 9.9 10.7 22.8 15.3 16.1 11.7 16.3 55.5 22.3 27.1 18.0 17.6 18.0 29.4 20.0 28.2 25.7 27.2 17.5 11.9 13.5 38.1 16.6 11.8 30.1 15.5 13.6 14.4 15.1 17.2 16.0 24.1 14.4 14.8 27.3 35.2 11.4 44.0 55.8 114.9 37.8 56.5 30.9 21.1 27.1 38.8 52.0 21.5 24.2 27.7 44.7 63.8 42.3 46.1 43.3 49.0 17.5 16.9 17.1 18.7 18.9 16.4 17.7 17.2 18.8 16.0 17.5 16.2 10.4 12.8 21.7 13.7 18.5 21.0 15.2 28.7 22.8 8.8 21.8 17.1 15.9 10.0 32.0 18.4 10.4 29.6 32.2 32.1 27.4 11.9 397.0 35.8 13.0 10.0 16.3 20.2 14.7 24.4 41.5 11.8 44.4 38.8 13.3 16.1 10.4 24.1 28.2 20.2 14.5 21.4 26.4 19.1 27.2 1576.6 17.4 26.4 12.4 11.2 40.3 13.7 39.1 9.0 8.1 19.6 18.5 23.3 20.5 31.5 27.8 47.3 33.0 9.9 0.0 8.9 14.8 180.5 22.9 20.5 23.0 75.5 25.9 20.8 27.0 16.9 PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 159.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1438.7;Basal squamous epithelial cells: 582.8;Urothelial cells: 760.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 296.3;RPTEC TERT1: 233.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" 21.3 31.0 9.9 17.3 10.1 21.8 28.1 8.9 11.0 23.1 6.2 8.9 6.5 13.4 4.4 59.8 7.8 39.3 20.6 10.3 11.3 14.8 67.6 27.1 5.9 10.8 16.9 19.2 17.9 5.3 8.2 14.3 11.3 8.9 10.2 13.8 159.1 8.2 5.8 11.5 8.6 14.8 9.6 19.5 22.5 3.1 11.5 7.4 27.2 1.5 7.5 60.9 33.7 11.3 60.9 71.5 54.9 30.4 25.0 51.6 3.9 50.5 134.7 22.4 30.8 39.7 72.2 0.3 14.8 21.2 73.8 30.7 1.5 84.2 47.9 9.3 1.2 1.5 3.8 68.2 36.3 1.4 15.1 16.2 60.6 93.2 182.6 296.3 54.4 0.1 5.0 1.7 115.8 7.8 0.2 7.9 20.1 36.3 108.7 0.2 14.3 1.8 233.7 135.1 4.0 10.4 8.8 0.8 169.5 67.8 35.5 0.7 50.8 75.8 7.2 89.3 50.4 0.8 0.3 0.2 127.9 0.8 96.7 0.2 0.0 0.0 0.9 0.1 1.5 0.0 0.9 1.0 0.0 0.0 0.1 0.2 0.2 0.0 1.1 0.0 1.6 0.2 9.9 10.1 8.9 11.0 10.3 11.3 10.8 16.9 11.3 9.6 11.5 11.3 98.5 12.8 12.4 7.2 13.0 195.3 1438.7 249.6 582.8 5.2 136.2 140.3 34.8 11.5 44.4 31.3 2.1 4.7 42.9 11.6 84.1 74.8 2.2 11.5 111.2 162.5 117.7 0.0 7.8 43.1 11.5 203.2 55.0 20.4 79.5 7.1 21.4 127.8 94.7 1.7 14.6 41.0 384.5 14.0 123.4 2.1 9.3 110.8 286.4 8.4 24.0 97.8 0.0 142.2 2.7 208.4 27.7 15.4 19.0 116.1 0.2 39.3 12.4 5.2 269.5 59.8 276.3 0.7 3.2 66.3 75.6 7.4 132.8 20.7 18.0 760.3 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PHYHD1 MGC16638 ENSG00000175287 "Phytanoyl-CoA dioxygenase domain containing 1" Q5SRE7 9 128920966-128942041 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Muller glia cells: 139.3;Proximal tubular cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 13.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 13.0" "Cell line enhanced" "Detected in many" "ASC diff: 46.5;ASC TERT1: 32.7;BEWO: 50.6;HSkMC: 28.3;RPTEC TERT1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012115 Approved "Nuclear speckles" NA NA 36000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles" "HPA012115: AB_1859448" "unprognostic (1.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.09e-3)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (4.49e-2)" "unprognostic (5.37e-3)" "unprognostic (1.35e-1)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (3.70e-2)" "prognostic favorable (6.38e-10)" "unprognostic (1.10e-2)" "unprognostic (3.09e-1)" "unprognostic (2.14e-1)" "unprognostic (9.83e-3)" 28.2 25.7 41.9 3.2 39.9 8.4 34.6 37.9 40.8 39.8 41.7 24.4 2.3 33.8 38.3 25.6 28.5 13.2 35.1 36.3 46.9 49.9 78.7 23.1 4.5 48.1 51.9 39.1 70.2 15.6 15.5 9.6 46.5 36.8 3.8 41.8 40.0 30.0 29.3 43.7 12.4 15.4 48.1 14.7 33.4 7.2 47.9 6.8 43.0 12.8 4.6 25.9 25.6 48.7 0.2 0.5 0.4 0.8 46.5 32.7 50.6 3.7 0.0 3.4 6.0 1.8 0.5 0.7 0.4 3.0 0.3 0.7 0.4 0.3 2.9 0.5 5.4 0.1 6.7 18.0 15.1 0.8 0.6 28.3 1.0 0.4 0.2 0.2 0.3 0.3 0.3 1.2 24.3 0.4 0.5 0.7 17.0 0.2 0.2 20.5 9.7 0.3 78.9 0.7 1.1 0.4 0.5 0.3 0.3 11.4 4.7 0.6 1.3 0.7 2.1 0.7 0.5 0.4 0.9 20.7 0.3 0.4 0.7 1.3 0.2 0.2 1.3 0.3 0.3 2.8 0.4 0.5 1.7 0.7 1.8 1.9 0.8 2.2 0.4 13.0 0.3 0.5 41.9 39.9 37.9 40.8 36.3 46.9 48.1 51.9 46.5 48.1 47.9 48.7 8.5 32.1 34.3 51.6 3.7 22.0 63.2 26.8 57.5 9.4 40.0 46.9 19.8 10.0 31.0 33.1 29.2 58.8 3.4 0.7 119.3 11.4 0.4 27.0 26.0 9.5 1.2 12.0 1.2 15.8 30.0 34.5 7.7 53.8 0.0 42.8 31.8 82.2 10.7 3.3 0.8 2.4 4.1 3.2 5.5 4.2 68.6 3.1 12.4 5.6 0.1 139.3 4.1 1.0 0.7 14.2 0.5 66.2 2.6 19.3 0.0 161.5 14.6 67.5 52.6 48.1 17.8 0.9 3.9 32.7 24.3 30.9 2.7 44.6 1.4 35.0 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIFO "C1orf88, FLJ23853, pitchfork" ENSG00000173947 "Primary cilia formation" Q8TCI5 1 111346600-111353013 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "fallopian tube: 174.2" "Group enriched" "Detected in many" 4 "Early spermatids: 430.6;Endometrial ciliated cells: 495.3;Late spermatids: 458.1;Respiratory ciliated cells: 990.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 3.4;RPTEC TERT1: 4.7;RT4: 5.9;SuSa: 7.9;T-47d: 3.8;U-87 MG: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.18e-3)" "unprognostic (3.23e-2)" "unprognostic (7.33e-2)" "unprognostic (3.03e-3)" "unprognostic (6.00e-2)" "unprognostic (7.43e-4)" "unprognostic (8.78e-7)" "unprognostic (6.43e-3)" "unprognostic (7.28e-2)" "unprognostic (9.07e-3)" "prognostic favorable (2.48e-4)" "unprognostic (3.32e-2)" "prognostic favorable (1.44e-4)" "unprognostic (6.03e-3)" "unprognostic (4.73e-2)" "unprognostic (6.37e-2)" "unprognostic (6.83e-2)" 1.0 2.8 8.6 0.7 9.1 0.1 5.7 8.2 9.2 4.3 36.5 5.1 0.6 7.4 12.5 3.5 174.2 3.5 9.3 8.5 10.8 8.3 0.0 12.9 0.3 14.3 15.0 3.3 6.4 15.1 9.8 2.9 13.7 12.2 1.1 5.1 3.1 6.0 0.1 1.4 1.1 4.7 12.2 0.4 4.4 24.8 10.8 1.7 15.0 0.9 0.6 5.4 0.8 14.0 0.0 0.0 0.5 0.6 0.6 0.7 1.0 0.0 1.2 0.2 0.0 0.8 1.1 0.0 0.2 0.0 1.1 0.0 0.8 0.2 0.0 1.4 0.2 0.0 0.1 0.9 0.4 0.0 0.0 0.4 3.2 0.0 0.0 3.4 0.0 0.2 0.2 0.1 2.0 0.3 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 4.7 5.9 2.2 0.2 0.0 0.1 0.1 7.9 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.4 3.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.4 0.2 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 9.1 8.2 9.2 8.5 10.8 14.3 15.0 13.7 12.2 10.8 14.0 0.3 3.2 18.5 3.3 0.5 4.2 9.1 71.5 1.8 0.7 6.0 12.6 17.3 0.0 83.2 5.5 4.2 11.6 0.1 0.0 21.5 13.0 430.6 495.3 5.8 1.6 3.0 0.0 0.5 2.0 4.4 3.7 1.5 9.0 0.0 3.8 0.7 0.1 1.2 0.0 1.4 0.0 77.3 0.0 0.7 458.1 5.9 1.5 8.8 0.0 0.0 11.8 0.0 0.5 0.6 1.2 0.0 3.4 0.4 6.2 0.0 36.3 990.5 5.4 6.6 4.6 22.8 127.1 10.5 0.5 2.8 7.0 1.0 8.4 0.1 4.3 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 78.9;Late spermatids: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.3 23.9 7.1 3.8 8.0 30.4 15.0 2.0 12.0 15.4 8.6 16.2 7.5 18.3 1.4 13.2 16.5 2.8 13.3 9.6 5.2 30.7 19.0 17.9 2.5 6.6 9.7 15.6 21.9 9.4 25.4 3.3 6.5 19.4 1.1 1.2 19.3 5.8 18.4 15.7 12.6 1.6 3.5 15.0 17.0 28.1 6.0 2.7 31.1 1.7 1.2 15.8 12.1 4.3 14.2 21.9 7.3 10.3 4.6 2.7 13.9 14.7 5.6 6.3 6.6 14.6 12.9 7.6 18.6 3.3 5.5 22.2 3.3 6.4 1.3 21.9 30.4 11.4 23.8 10.8 8.9 10.1 10.2 5.2 9.8 10.2 2.0 4.0 6.1 13.7 26.1 4.1 2.1 20.7 18.3 11.4 10.0 3.0 21.9 36.6 6.4 17.7 5.6 5.6 13.2 21.4 16.8 7.6 10.8 2.3 17.3 6.9 14.5 10.4 13.7 11.7 10.4 15.8 5.0 6.0 4.8 5.4 10.4 0.9 2.8 1.6 2.8 3.1 2.4 2.3 2.3 2.6 2.7 2.5 2.5 1.6 3.0 3.3 3.7 5.6 2.4 2.6 7.1 8.0 2.0 12.0 9.6 5.2 6.6 9.7 6.5 3.5 6.0 4.3 9.7 16.0 20.3 14.0 6.9 4.8 6.6 8.4 5.2 12.1 15.8 11.0 8.4 4.3 10.6 40.5 4.2 10.5 8.8 31.5 3.9 19.3 33.6 21.0 7.8 9.0 20.3 78.9 19.3 17.4 8.4 9.4 16.3 11.4 8.2 19.7 6.4 16.4 9.5 10.1 13.8 13.0 8.2 9.1 4.4 61.4 7.5 8.2 16.0 3.7 7.7 14.6 10.3 7.5 6.6 14.1 11.6 7.2 9.1 6.9 7.6 12.4 23.3 13.7 0.0 7.7 9.9 30.1 13.6 6.2 4.8 5.9 7.8 11.1 16.9 5.0 PIP "GCDFP-15, GCDFP15, GPIP4" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16791.8" "Group enriched" "Detected in many" 4 "Breast glandular cells: 1117.6;Breast myoepithelial cells: 324.2;Melanocytes: 403.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 333 "T-47d: 703.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" NA NA 66000000 "Cluster 37: B-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" 9.1 3.6 0.7 0.2 4.8 0.1 3458.7 2.7 2.7 5.6 0.0 0.5 0.0 0.1 2.7 1.3 4.2 0.1 4.8 0.9 4.6 0.5 2.0 6.4 0.8 8.5 4.4 3.8 21.1 0.4 1.9 2.3 6.8 33.3 0.0 0.0 16791.8 3140.5 1.7 189.7 0.6 0.0 3.5 0.6 0.6 0.7 4.6 0.3 0.7 0.0 1.8 0.6 1.5 11.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 1.3 0.0 0.0 0.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 703.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.8 2.7 2.7 0.9 4.6 8.5 4.4 6.8 3.5 4.6 11.5 6.9 0.0 2.0 0.0 3.6 10.8 6.6 18.8 0.0 0.0 1117.6 324.2 0.1 0.0 48.2 1.8 0.0 0.0 7.0 0.0 0.0 9.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 2.5 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.4 0.0 1.6 0.0 0.0 1.5 403.8 0.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 0.0 0.0 13.1 0.0 0.1 147.1 0.0 0.0 0.0 9.2 0.0 0.0 0.0 1.7 0.0 2.5 0.0 0.0 13.7 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 67.9" "Cell type enhanced" "Detected in single" "dendritic cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.3;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 10 "B-cells: 17.3" "Cell line enriched" "Detected in some" 8 "U-266/70: 128.9" HPA058997 Approved Approved Mitochondria NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" 0.3 0.0 0.6 0.8 0.6 0.1 9.1 0.5 0.9 0.9 0.3 11.2 67.9 0.3 1.2 1.5 4.7 0.6 0.2 0.5 0.5 8.6 4.6 3.6 0.3 0.7 0.6 0.2 0.0 0.0 0.2 0.2 0.6 0.4 13.7 0.0 0.9 0.5 0.0 0.3 42.5 0.3 0.5 0.7 12.4 0.5 0.6 0.3 0.9 0.0 0.3 1.3 0.2 1.1 0.4 1.7 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 0.1 0.3 15.6 0.0 0.9 0.0 0.4 1.0 0.6 0.2 0.1 0.2 0.0 0.1 1.0 0.1 0.2 0.0 0.1 0.1 1.2 0.3 0.0 0.7 0.0 0.0 0.0 6.7 0.0 0.0 0.2 0.3 0.1 8.7 1.9 0.0 0.0 1.5 0.6 0.0 0.0 0.2 0.1 4.0 0.0 0.1 2.2 0.1 0.0 0.0 0.0 0.1 0.0 128.9 16.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.9 17.3 0.2 1.0 0.1 8.2 0.2 0.7 0.1 1.6 0.0 0.9 0.0 3.9 0.6 0.6 0.5 0.9 0.5 0.5 0.7 0.6 0.6 0.5 0.6 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 365.9;esophagus: 92.0;intestine: 236.0;lymphoid tissue: 155.1;stomach 1: 117.5" "Cell type enhanced" "Detected in many" "dendritic cells: 1118.2;Distal enterocytes: 1514.4;Extravillous trophoblasts: 572.2;NK-cells: 1103.0;Paneth cells: 865.7;Respiratory ciliated cells: 549.6" "Cancer enhanced" "Detected in many" "stomach cancer: 17.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2310.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 183.2;CAPAN-2: 510.7;HL-60: 329.1;NB-4: 160.1;RPMI-8226: 238.2;THP-1: 187.8;U-937: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA040465: AB_10794875, HPA077912: AB_2686870" "unprognostic (6.82e-5)" "prognostic favorable (3.03e-4)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.05e-1)" "unprognostic (4.86e-2)" "unprognostic (1.14e-1)" "unprognostic (1.94e-3)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (7.44e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-7)" "unprognostic (3.89e-2)" "unprognostic (2.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" 9.2 2.0 1.8 81.3 2.0 365.9 3.8 2.8 2.4 32.8 1.4 236.0 78.9 2.7 1.2 92.0 18.7 6.5 2.8 1.5 1.7 2.6 35.4 41.2 93.8 7.8 2.7 1.0 1.6 0.5 2.0 33.7 5.5 3.7 163.3 1.1 6.6 2.3 2.0 1.0 88.5 18.5 2.3 155.1 117.5 0.8 2.4 40.5 2.6 0.8 137.5 11.0 5.8 3.7 183.2 1.3 0.5 1.1 0.0 0.2 28.6 4.6 1.1 11.1 13.7 3.5 510.7 30.7 1.5 52.3 17.0 18.7 3.2 1.4 41.6 0.2 0.6 0.8 33.4 15.2 1.8 329.1 1.7 0.9 3.6 1.8 2.4 0.3 0.8 16.0 0.4 2.6 29.5 0.8 62.6 160.1 1.0 14.4 0.9 8.0 10.6 238.2 0.9 5.4 25.8 0.5 1.2 29.1 0.6 9.0 1.6 187.8 1.3 1.1 31.7 0.9 0.9 1.8 0.4 81.7 2.3 149.7 0.2 49.2 139.2 95.9 392.1 635.8 299.4 523.8 185.1 229.2 129.5 481.1 225.9 263.4 29.7 1053.3 358.9 2310.7 13.8 577.1 1.8 2.0 2.8 2.4 1.5 1.7 7.8 2.7 5.5 2.3 2.4 3.7 4.3 195.5 39.2 0.3 247.4 0.4 1.7 77.3 0.0 0.3 0.9 1.4 0.5 2.8 119.1 0.0 0.0 18.5 1118.2 1514.4 0.0 0.3 0.5 45.6 1.1 95.0 86.8 58.4 0.1 3.6 572.2 3.1 119.8 2.9 26.6 0.6 141.0 8.4 21.7 1.7 0.1 231.2 67.1 384.5 7.4 0.6 0.0 213.3 7.2 1.0 157.3 1.2 1103.0 0.0 0.2 99.0 865.7 0.0 35.7 1.1 374.4 1.4 549.6 0.3 6.6 0.7 8.0 0.2 0.8 10.1 0.1 14.2 150.6 0.1 104.2 9.0 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLCH2 "KIAA0450, PLC-eta2, PLCeta2, PLCL4, RP3-395M20.1" ENSG00000149527 "Phospholipase C eta 2" O75038 1 2425980-2505532 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 44.8;skin 1: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.5;Cone photoreceptor cells: 75.0;Oligodendrocytes: 37.4;Rod photoreceptor cells: 169.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HBEC3-KT: 130.9;hTCEpi: 58.9;hTERT-HME1: 32.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072705 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA072705: AB_2732211" "unprognostic (2.06e-3)" "unprognostic (1.30e-2)" "unprognostic (1.09e-3)" "unprognostic (3.84e-3)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (7.39e-2)" "unprognostic (7.70e-2)" "unprognostic (7.58e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" "unprognostic (5.95e-2)" "unprognostic (6.61e-3)" "unprognostic (8.43e-2)" "unprognostic (1.07e-1)" "unprognostic (8.64e-2)" "unprognostic (5.80e-2)" 0.6 1.4 1.0 3.9 1.7 2.2 6.2 7.9 4.8 6.3 0.0 1.1 2.2 0.3 1.7 19.3 3.2 2.9 0.2 2.4 1.0 0.8 2.1 1.8 5.3 3.3 3.1 0.1 5.1 0.0 7.9 0.4 3.6 14.6 0.8 44.8 16.4 5.8 0.2 59.6 3.3 0.1 1.2 5.5 2.0 0.6 6.9 4.4 1.7 0.0 6.5 9.1 18.3 7.2 0.3 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.2 0.0 17.1 0.0 130.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 58.9 0.0 32.8 0.0 0.0 0.0 0.0 3.1 0.3 0.6 0.0 0.0 0.1 1.9 1.4 0.1 0.1 0.0 0.2 6.1 14.7 2.9 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.0 0.6 0.2 1.0 1.7 7.9 4.8 2.4 1.0 3.3 3.1 3.6 1.2 6.9 7.2 0.2 0.0 1.7 2.9 6.1 15.4 14.5 22.8 10.8 102.5 1.7 5.5 3.3 2.8 10.8 0.0 75.0 0.0 7.3 0.7 1.9 0.1 0.1 0.7 0.2 0.7 1.2 0.0 9.3 0.0 0.0 0.4 1.5 1.4 0.0 0.1 0.0 4.9 0.1 26.9 19.8 1.9 2.0 0.3 1.1 0.2 0.0 0.5 3.6 1.9 0.4 14.9 7.2 2.5 37.4 0.5 0.6 0.0 1.9 4.9 3.8 33.5 5.8 169.0 0.0 0.0 1.0 0.2 0.3 13.0 14.6 0.0 7.0 0.1 0.5 9.2 PLCXD2 FLJ31579 ENSG00000240891 "Phosphatidylinositol specific phospholipase C X domain containing 2" Q0VAA5 3 111674676-111846447 "Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.3;retina: 14.8" "Cell type enhanced" "Detected in many" "Collecting duct cells: 60.7;Distal tubular cells: 160.4;Hepatocytes: 168.6;Proximal tubular cells: 196.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.8" "Group enriched" "Detected in many" 5 "dendritic cells: 3.8;NK-cells: 1.1;T-cells: 1.8" "Cell line enhanced" "Detected in many" "HBF TERT88: 7.1" "Low region specificity" "Detected in all" HPA055947 Uncertain Approved Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055947: AB_2682981" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (7.26e-2)" "unprognostic (2.42e-1)" "unprognostic (3.09e-2)" "unprognostic (2.76e-2)" "unprognostic (1.36e-1)" "unprognostic (4.64e-1)" "unprognostic (3.47e-1)" "unprognostic (1.99e-2)" "unprognostic (3.38e-2)" "unprognostic (2.04e-1)" "prognostic favorable (1.23e-7)" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "prognostic favorable (2.99e-4)" 0.3 0.3 2.6 1.6 2.9 4.6 0.2 0.7 7.3 0.3 0.0 1.2 2.8 0.3 0.2 0.5 0.2 0.7 0.3 3.9 1.6 0.6 1.0 0.6 2.9 4.1 4.5 0.2 0.6 0.1 1.4 1.0 4.1 0.3 1.5 14.8 0.9 0.2 0.2 0.6 2.7 0.3 2.2 1.6 0.9 1.0 3.5 2.7 1.3 0.1 2.2 0.5 0.3 1.9 2.3 2.1 2.0 0.9 0.0 0.1 0.6 4.0 1.9 3.7 3.2 1.4 1.1 1.7 2.0 0.2 1.2 5.6 0.8 3.7 7.1 0.5 1.0 0.4 4.1 1.3 0.3 0.5 2.0 0.0 0.7 1.2 2.2 3.4 2.0 2.1 0.0 4.0 0.4 0.2 1.2 0.4 0.7 1.5 5.1 1.1 2.8 1.6 1.7 2.3 0.4 3.4 0.8 0.5 0.8 2.2 0.3 0.1 2.0 0.8 5.0 0.4 0.8 4.8 0.7 0.3 0.4 0.3 0.2 0.3 0.0 0.0 1.8 0.0 1.8 0.3 0.9 1.8 0.1 0.4 0.4 0.9 0.1 1.1 0.0 3.8 0.9 0.3 2.6 2.9 0.7 7.3 3.9 1.6 4.1 4.5 4.1 2.2 3.5 1.9 0.4 19.2 2.2 3.3 2.3 0.1 9.9 17.1 7.4 0.8 2.9 1.8 3.7 22.8 3.5 60.7 4.2 0.0 8.4 1.6 160.4 44.2 11.9 0.9 0.2 0.7 25.1 0.0 11.7 50.1 0.0 0.4 7.1 1.5 0.0 5.4 0.4 168.6 0.0 6.7 6.0 7.8 2.0 1.6 0.0 12.0 0.3 1.8 0.0 3.7 0.0 0.0 2.1 7.5 0.9 50.1 0.2 0.4 3.9 7.9 1.0 196.6 1.0 3.5 0.0 0.0 1.7 0.5 0.5 2.2 0.1 0.0 5.3 0.5 1.5 14.1 PLD3 HU-K4 ENSG00000105223 "Phospholipase D family member 3" Q8IV08 19 40348456-40380439 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 711.9" "Cell type enhanced" "Detected in all" "Hofbauer cells: 688.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 1727.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 1727.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012800, CAB020812" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA 450000 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB020812: , HPA012800: AB_1855330" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.64e-3)" "unprognostic (2.56e-3)" "unprognostic (2.06e-3)" "unprognostic (2.68e-1)" "unprognostic (4.52e-2)" "unprognostic (3.89e-2)" "unprognostic (1.09e-1)" "unprognostic (4.60e-2)" "prognostic favorable (6.44e-4)" "unprognostic (4.34e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (6.42e-2)" 169.3 200.0 143.3 78.4 159.7 48.3 138.4 46.0 229.7 139.4 54.0 131.4 71.7 155.7 84.7 84.9 133.5 96.7 206.1 202.5 294.4 130.2 121.3 181.5 98.1 132.4 128.5 199.0 151.0 105.9 711.9 123.4 137.9 133.4 49.2 51.4 138.7 106.2 105.1 120.5 105.3 79.1 63.8 197.0 126.5 77.7 197.7 44.3 120.8 82.3 41.4 126.2 126.0 129.6 85.6 257.8 163.7 259.1 444.2 210.2 124.5 206.5 208.6 146.4 166.6 49.4 93.8 36.9 211.0 180.9 47.8 39.3 39.9 81.2 63.5 138.4 145.3 39.9 82.1 63.2 302.7 16.8 435.1 402.5 167.0 112.1 76.6 244.2 125.0 59.3 142.5 144.5 106.7 111.5 29.5 79.6 107.4 138.7 52.8 37.0 124.5 154.2 75.2 63.2 116.7 193.9 99.0 60.6 113.8 169.5 83.6 283.2 222.3 122.8 58.5 105.6 47.0 148.9 173.3 38.8 197.7 66.2 77.9 1727.4 256.7 378.7 75.0 129.5 62.0 34.4 59.5 67.7 235.0 28.1 60.8 61.3 25.7 102.3 64.2 34.7 64.5 208.6 143.3 159.7 46.0 229.7 202.5 294.4 132.4 128.5 137.9 63.8 197.7 129.6 66.7 32.1 69.6 59.4 27.0 35.4 93.6 263.1 39.9 101.5 45.9 61.2 22.0 45.8 90.4 57.0 33.3 158.2 27.2 42.5 21.5 52.5 8.7 32.0 49.8 53.9 72.8 18.7 99.1 58.3 107.2 158.8 38.2 31.5 60.3 134.7 88.2 43.1 688.4 121.1 113.4 41.3 126.1 280.9 59.1 15.7 151.6 261.3 92.5 50.6 54.2 94.1 35.0 53.3 70.2 54.3 42.6 143.7 85.8 57.9 78.8 37.1 35.2 47.6 19.7 73.1 59.7 24.2 67.9 32.4 33.4 195.9 28.8 114.1 41.6 68.2 PLEKHD1 UPF0639 ENSG00000175985 "Pleckstrin homology and coiled-coil domain containing D1" A6NEE1 14 69484692-69531551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;parathyroid gland: 6.0;retina: 8.8" "Group enriched" "Detected in some" 13 "Bipolar cells: 60.9;Horizontal cells: 230.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 3.7" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.7" "Cell line enhanced" "Detected in some" "OE19: 1.1;SK-BR-3: 2.4;T-47d: 2.3;U-266/70: 1.0" "Region enhanced" "Detected in many" "cerebellum: 30.0" "Low region specificity" "Detected in many" HPA051875 Uncertain NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "HPA051875: AB_2681648" "unprognostic (8.73e-2)" "unprognostic (4.64e-3)" "unprognostic (3.73e-2)" "unprognostic (4.03e-2)" "unprognostic (7.58e-2)" "unprognostic (3.15e-3)" "unprognostic (1.44e-1)" "unprognostic (1.64e-3)" "unprognostic (3.28e-1)" "unprognostic (1.83e-1)" "unprognostic (4.56e-3)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (8.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.74e-2)" "unprognostic (1.42e-2)" 0.1 0.2 1.2 0.1 0.5 0.5 0.6 8.1 2.4 0.3 0.0 0.0 0.2 0.1 1.6 0.1 0.1 0.1 0.1 0.3 1.4 1.4 0.0 0.2 0.9 1.4 3.2 0.1 0.2 6.0 0.3 0.1 1.6 0.1 0.0 8.8 1.6 0.3 0.1 1.5 0.1 0.0 0.4 0.2 0.2 1.2 4.5 0.1 2.2 0.0 0.2 0.0 0.0 1.1 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.1 0.2 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.3 0.7 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.1 0.3 0.1 0.1 1.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.7 0.0 0.0 1.2 0.5 8.1 2.4 0.3 1.4 1.4 3.2 1.6 0.4 4.5 1.1 0.5 0.0 7.3 0.3 0.0 0.4 1.8 0.1 0.0 60.9 0.6 0.4 1.3 0.0 2.0 0.0 4.2 0.1 11.2 0.1 3.9 0.1 0.5 0.4 0.2 1.0 0.0 0.0 6.3 0.2 0.1 0.6 0.0 0.6 1.3 0.1 0.4 0.0 0.1 230.5 3.3 0.0 0.0 0.0 0.6 0.1 0.0 1.0 0.0 0.0 0.6 1.7 1.0 0.0 0.1 0.3 0.0 0.0 0.0 1.4 0.2 0.5 0.9 5.9 0.0 1.4 0.6 0.8 0.3 0.0 0.3 0.1 2.3 0.2 0.1 0.7 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLSCR4 ENSG00000114698 "Phospholipid scramblase 4" Q9NRQ2 3 146192335-146251179 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 77.3;Astrocytes: 151.1;Endothelial cells: 63.4;Hepatic stellate cells: 110.3;Oligodendrocyte precursor cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.5;ASC TERT1: 48.2;hTERT-RPE1: 62.1;HUVEC TERT2: 50.8;TIME: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002276 Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA002276: AB_1855479" "unprognostic (3.73e-3)" "unprognostic (4.03e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.62e-1)" "unprognostic (6.77e-3)" "unprognostic (1.19e-1)" "unprognostic (4.36e-2)" "unprognostic (7.33e-2)" "unprognostic (2.49e-1)" "unprognostic (2.50e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (4.13e-4)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" "unprognostic (8.13e-3)" "unprognostic (2.97e-3)" 60.2 43.8 30.2 9.4 28.2 2.3 41.9 30.9 32.5 28.9 11.6 27.4 6.8 30.1 15.7 23.2 41.2 45.6 28.0 28.7 38.5 25.3 69.0 37.4 10.5 39.3 44.0 36.4 20.5 4.3 11.2 56.4 32.6 13.8 25.2 13.7 23.6 25.8 7.4 16.1 13.6 33.7 36.9 30.1 14.4 21.6 41.8 6.6 31.2 18.8 6.7 19.8 25.5 32.2 0.0 9.9 1.7 0.0 60.5 48.2 0.3 11.5 15.7 5.0 10.9 1.0 12.6 0.0 12.3 21.0 5.0 1.4 2.4 1.1 2.8 0.1 0.1 5.0 7.9 1.3 28.1 0.1 1.3 29.6 1.6 10.4 3.0 62.1 50.8 0.0 0.2 0.9 7.4 0.3 0.0 0.1 2.1 5.1 3.4 0.0 0.8 0.0 0.1 0.0 0.6 0.0 20.1 0.1 3.9 2.5 0.7 0.6 106.4 10.4 2.6 23.6 2.1 0.3 0.0 0.0 2.6 0.1 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.2 28.2 30.9 32.5 28.7 38.5 39.3 44.0 32.6 36.9 41.8 32.2 77.3 3.2 10.3 151.1 1.0 10.8 5.6 0.8 12.0 0.6 10.2 8.6 4.1 25.8 6.0 3.7 0.0 0.7 0.3 27.4 0.0 8.2 1.1 3.6 11.6 63.4 10.3 15.6 1.7 11.6 0.5 57.1 2.0 1.5 1.3 7.0 110.3 44.1 0.8 0.0 0.6 11.7 0.0 7.1 11.8 3.8 42.9 1.1 3.6 40.3 0.1 51.4 0.0 61.3 0.6 4.7 13.3 32.4 2.8 2.6 6.4 28.3 6.4 1.5 0.0 18.9 23.6 1.2 0.9 4.8 8.7 0.8 1.8 20.0 8.1 2.7 PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Microglial cells: 1508.4;Oligodendrocytes: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.5;intermediate monocyte: 33.4;myeloid DC: 36.0;neutrophil: 81.6;non-classical monocyte: 37.3" "Group enriched" "Detected in many" 13 "dendritic cells: 36.0;granulocytes: 81.6;monocytes: 57.5" "Cell line enhanced" "Detected in some" "HHSteC: 19.4;U-2197: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 720000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies" "HPA017268: AB_10965928, HPA070793: AB_2686313" "unprognostic (1.75e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (3.05e-1)" "unprognostic (3.31e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-2)" "unprognostic (1.57e-1)" "unprognostic (5.32e-2)" "unprognostic (7.52e-2)" "unprognostic (1.89e-1)" "unprognostic (1.35e-1)" "unprognostic (5.44e-2)" "unprognostic (3.91e-3)" "unprognostic (8.71e-2)" "unprognostic (3.35e-1)" "unprognostic (2.66e-2)" 12.4 9.4 13.3 7.3 14.1 5.2 11.5 9.6 13.3 12.7 16.8 5.3 4.2 10.7 3.5 7.5 10.1 17.4 10.2 11.3 25.6 10.7 3.1 17.1 2.4 18.0 17.3 9.4 3.6 16.2 3.3 4.7 19.2 7.6 4.6 18.2 6.2 7.7 5.0 15.5 7.1 16.2 16.2 9.4 3.8 5.9 22.3 2.5 6.8 10.0 2.8 8.5 8.9 29.1 0.0 0.0 5.8 0.0 0.0 0.0 6.7 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 7.7 2.2 1.8 0.0 0.0 0.7 2.8 8.6 0.4 19.4 0.0 0.0 7.7 0.6 0.0 2.3 8.9 0.0 0.0 0.1 1.7 0.9 1.1 0.6 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.4 0.2 2.4 0.4 0.0 1.8 0.8 0.9 0.0 7.6 3.9 45.9 0.0 0.1 0.0 0.0 3.5 0.1 0.0 10.7 57.5 11.8 1.3 33.4 2.7 0.0 0.0 0.3 36.0 0.0 0.0 0.0 81.6 4.4 37.3 1.6 0.0 17.7 13.3 14.1 9.6 13.3 11.3 25.6 18.0 17.3 19.2 16.2 22.3 29.1 101.4 16.0 8.9 131.9 2.6 36.8 23.8 12.3 41.5 44.2 14.4 45.3 10.9 15.7 10.9 5.5 8.4 0.9 2.9 7.1 0.0 6.9 2.9 16.5 7.6 45.3 3.0 10.5 190.9 0.0 8.1 97.2 1.1 19.4 31.6 80.9 82.1 4.2 94.3 1.7 59.9 27.3 8.2 91.3 46.3 2.1 19.3 147.7 7.2 1508.4 94.5 25.5 5.2 158.3 470.2 1.0 16.6 57.2 3.8 5.5 16.0 22.2 3.0 73.6 19.7 110.1 12.7 1.6 1.2 35.5 38.1 1.2 4.2 71.4 8.8 11.7 PLXNA2 "FLJ11751, FLJ30634, KIAA0463, OCT, PLXN2" ENSG00000076356 "Plexin A2" O75051 1 208022242-208244384 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 35.1" "Cell type enhanced" "Detected in many" "Astrocytes: 100.6;Excitatory neurons: 134.7;Horizontal cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 52.8;HaCaT: 55.4;HUVEC TERT2: 70.3;TIME: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009763 Approved NA NA 1400000 "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB009763: AB_2166388" "unprognostic (8.25e-2)" "unprognostic (3.91e-2)" "unprognostic (8.85e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.07e-1)" "unprognostic (1.97e-2)" "unprognostic (4.84e-2)" "unprognostic (6.88e-3)" "unprognostic (7.06e-2)" "unprognostic (2.61e-1)" "unprognostic (8.41e-2)" "unprognostic (4.49e-3)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (1.27e-2)" "unprognostic (2.40e-1)" 7.9 1.4 6.6 2.1 9.1 0.4 4.9 10.5 11.2 3.9 19.0 9.0 6.8 6.0 2.0 15.4 5.2 4.0 8.8 10.0 1.6 3.4 2.4 14.3 1.0 2.2 7.8 13.8 35.1 1.3 3.0 8.5 3.2 4.1 7.2 3.7 4.1 3.1 9.6 9.5 7.7 5.9 4.5 1.3 9.0 0.6 2.7 4.3 6.8 9.4 2.4 9.4 6.3 7.7 6.4 3.7 6.9 1.0 7.6 14.7 52.8 5.0 3.1 3.0 0.5 0.2 0.1 0.0 9.8 3.9 1.3 55.4 0.1 31.4 0.9 1.9 1.1 0.0 6.9 3.7 3.2 0.0 0.2 3.9 10.0 2.4 14.2 2.0 70.3 0.0 0.0 0.0 30.7 0.7 0.1 0.1 1.1 11.2 9.4 0.0 7.0 4.7 5.7 4.0 2.0 12.5 5.9 4.5 5.5 13.3 0.5 0.0 162.9 1.1 1.7 5.9 10.4 0.3 0.0 0.0 6.5 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 9.1 10.5 11.2 10.0 1.6 2.2 7.8 3.2 4.5 2.7 7.7 50.7 28.9 28.6 100.6 1.7 4.8 16.2 12.9 30.1 12.7 2.9 2.2 5.8 7.2 25.6 0.0 2.1 5.3 0.8 64.6 1.9 4.2 0.9 13.8 0.9 48.1 9.1 0.0 134.7 15.3 2.5 9.6 44.4 9.5 6.3 1.1 36.8 5.9 3.3 249.0 62.9 29.0 8.2 5.5 6.0 0.6 9.9 4.4 5.4 54.4 1.4 0.4 1.0 44.7 3.1 23.3 52.2 6.8 1.7 8.2 33.6 2.2 8.5 2.7 6.6 26.3 8.1 1.9 1.0 41.1 10.5 1.9 1.1 1.4 26.5 22.7 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207880-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 39.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 20.9" "Lineage enriched" "Detected in all" 5 "monocytes: 20.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" NA NA 60000 "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" 17.6 10.8 7.9 11.7 8.4 10.5 16.5 7.2 7.7 15.2 9.1 20.0 20.4 14.9 14.4 12.4 20.4 11.4 17.5 7.7 7.3 16.1 30.9 12.2 9.1 9.3 8.3 20.0 13.8 23.8 9.1 16.4 8.0 14.5 19.1 5.9 13.0 18.1 12.8 13.7 24.0 18.1 8.0 9.4 11.1 9.5 8.1 10.5 18.9 14.0 10.0 14.0 10.9 8.2 47.1 37.2 31.5 34.7 52.9 51.4 58.8 47.8 56.2 78.8 51.3 111.9 62.1 31.7 69.8 53.5 87.2 51.2 30.5 59.0 68.0 16.5 19.2 47.1 32.1 51.2 41.2 41.0 28.9 45.4 45.7 59.7 38.8 33.5 44.6 30.0 36.3 17.6 55.6 23.1 28.4 31.4 16.2 45.2 59.4 23.3 83.6 29.5 24.2 30.7 20.6 26.5 109.5 30.0 41.0 24.0 44.7 48.5 38.8 113.4 42.2 71.8 82.4 21.4 29.3 28.7 68.5 139.9 73.0 4.3 5.4 2.6 3.2 15.1 3.6 3.2 2.8 3.0 4.6 2.6 3.6 2.5 1.0 2.0 20.9 3.4 3.3 4.2 7.9 8.4 7.2 7.7 7.7 7.3 9.3 8.3 8.0 8.0 8.1 8.2 7.8 9.6 9.5 11.1 5.2 2.9 4.7 8.6 5.2 3.1 7.2 7.1 13.4 8.6 7.9 7.3 2.1 15.2 5.7 17.5 1.9 10.0 0.9 7.1 10.8 9.3 12.0 9.2 9.0 10.4 28.2 12.0 9.2 13.6 5.1 13.1 13.9 39.8 10.7 8.4 9.0 13.4 2.0 8.1 3.8 1.7 10.5 6.5 5.4 6.5 9.3 5.2 3.1 11.1 9.6 9.6 11.9 14.3 8.2 6.7 31.7 5.3 7.2 4.3 13.1 11.1 9.4 2.9 7.3 9.7 1.7 7.7 5.0 26.0 19.0 4.1 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POPDC2 POP2 ENSG00000121577 "Popeye domain containing 2" Q9HBU9 3 119636457-119665324 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 405.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 272.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 24.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA024255 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA024255: AB_1855545" "unprognostic (1.13e-1)" "unprognostic (1.17e-3)" "unprognostic (8.91e-3)" "unprognostic (9.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.43e-1)" "unprognostic (3.18e-2)" "unprognostic (1.72e-2)" "unprognostic (5.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (6.26e-3)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-2)" 3.6 2.1 0.6 3.8 0.5 0.3 3.3 0.8 0.9 7.9 1.3 95.3 2.8 12.5 2.6 2.0 9.6 10.9 405.4 0.5 0.5 2.4 1.0 2.5 6.7 0.6 0.6 2.0 1.3 8.4 1.3 1.4 0.6 16.3 6.2 0.9 3.3 49.2 77.7 2.8 12.2 24.0 0.5 2.8 10.7 1.0 0.6 1.5 2.4 96.9 2.5 35.3 6.0 0.5 0.1 0.2 0.5 0.0 0.2 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.4 1.0 0.0 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.2 0.0 0.3 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.2 24.8 0.0 0.0 0.6 2.5 0.0 0.3 0.0 0.2 0.1 0.2 0.1 1.0 0.0 0.2 0.2 0.3 0.5 0.5 0.0 0.7 0.3 0.0 0.4 0.1 0.5 0.4 0.0 0.4 0.8 0.2 0.0 0.2 1.3 0.2 0.7 0.1 0.6 0.5 0.8 0.9 0.5 0.5 0.6 0.6 0.6 0.5 0.6 0.5 4.7 0.0 0.5 1.0 0.6 0.4 0.3 0.5 0.0 3.1 0.9 3.0 272.7 0.0 0.9 0.0 0.0 0.5 2.3 0.4 0.0 0.5 0.3 0.6 0.5 6.4 3.0 0.0 0.8 0.2 0.1 8.0 0.5 0.3 1.3 1.6 1.4 0.2 1.6 1.7 1.2 0.8 0.0 1.0 2.3 0.8 1.2 1.6 0.0 2.8 1.8 1.2 0.0 1.0 1.9 0.5 0.2 1.9 0.0 0.8 0.7 0.3 1.9 2.4 59.2 5.9 11.1 1.0 0.3 0.1 0.6 1.2 1.6 0.6 0.3 0.2 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PRDM6 "KMT8C, PRISM" ENSG00000061455 "PR/SET domain 6" Q9NQX0 5 123089241-123194266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;urinary bladder: 9.0" "Cell type enhanced" "Detected in some" "Astrocytes: 15.0;Endometrial stromal cells: 6.5;Excitatory neurons: 7.9;Fibroblasts: 10.7;Late spermatids: 7.1;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.6;HEK 293: 5.2;HEL: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.3" HPA030324 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 28: BEWO - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA030324: AB_10670032" "unprognostic (2.33e-1)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (2.32e-3)" "unprognostic (3.12e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-2)" "unprognostic (4.66e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-7)" "unprognostic (9.30e-4)" "unprognostic (1.10e-1)" "unprognostic (3.43e-4)" "unprognostic (1.27e-1)" 0.7 0.1 0.2 0.3 0.2 0.0 0.6 0.2 0.3 0.9 0.6 4.9 0.2 0.7 0.1 0.6 0.4 3.3 0.5 0.1 0.2 0.3 0.1 2.9 0.0 0.3 0.4 1.9 0.3 0.1 0.3 4.2 0.4 1.3 1.0 0.2 0.1 0.1 0.1 0.2 0.6 0.7 0.3 0.0 0.6 0.3 0.2 0.0 0.8 0.2 0.2 9.0 0.6 0.3 0.0 0.0 0.0 0.3 0.3 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.0 0.1 5.2 1.1 0.5 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.3 0.5 0.0 0.0 15.0 0.0 1.9 0.1 0.0 0.0 1.0 0.6 0.3 1.4 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.1 3.3 0.6 6.5 0.5 0.0 0.0 7.9 0.2 0.3 10.7 0.0 0.5 0.0 2.4 0.0 0.5 0.8 0.0 6.4 0.1 0.0 0.8 3.5 7.1 2.1 0.4 3.6 4.7 0.8 0.2 0.0 3.0 11.0 0.1 0.0 1.2 0.1 0.2 0.0 0.8 0.2 1.0 0.0 0.7 2.2 2.3 4.4 0.2 1.3 0.4 0.4 6.1 0.0 0.1 PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 26.1;seminal vesicle: 27.2" "Cell type enriched" "Detected in many" 9 "Bipolar cells: 271.5" "Cancer enhanced" "Detected in many" "prostate cancer: 4.6" "Region enhanced" "Detected in many" "cerebral cortex: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 27.3;LHCN-M2: 41.7;NB-4: 48.2;SCLC-21H: 99.3" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 24: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Nuclear bodies" Nucleoplasm "HPA057253: AB_2683382" "unprognostic (2.33e-2)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (2.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (1.65e-1)" "unprognostic (7.95e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (2.80e-2)" "unprognostic (1.89e-11)" "unprognostic (4.64e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-1)" 4.8 2.3 5.1 5.0 10.2 4.0 4.0 0.0 17.0 11.7 0.0 11.4 1.1 9.3 1.9 1.7 5.2 1.7 1.7 13.7 0.0 1.3 0.3 1.6 5.1 0.0 0.0 5.2 0.9 0.0 5.4 4.3 0.0 26.1 1.5 24.1 1.4 27.2 2.2 2.7 5.7 3.8 0.6 1.8 5.0 1.1 0.1 0.7 1.2 0.9 2.4 10.2 9.8 3.2 2.3 0.2 0.7 0.0 2.1 7.2 0.1 5.8 20.5 2.8 3.2 0.0 2.2 0.0 0.0 7.2 1.8 0.7 0.1 2.4 12.1 8.8 1.8 0.8 0.0 0.0 4.1 9.1 2.5 4.4 0.2 11.1 3.2 27.3 0.4 2.4 0.0 3.7 41.7 0.0 4.2 48.2 0.0 0.2 17.0 1.6 0.0 0.2 1.2 0.3 99.3 13.8 0.3 0.0 0.1 0.1 0.0 4.5 8.8 7.1 1.0 5.2 0.4 1.7 0.0 0.0 17.8 4.2 1.0 0.0 0.0 0.0 0.4 0.0 0.6 0.1 0.5 0.5 0.1 0.7 0.3 0.1 0.5 0.2 0.0 0.1 0.2 0.1 5.1 10.2 0.0 17.0 13.7 0.0 0.0 0.0 0.0 0.6 0.1 3.2 0.9 0.0 0.5 2.3 8.2 0.6 3.4 0.4 0.0 271.5 0.1 0.4 1.8 0.0 5.2 1.8 2.1 0.0 2.5 0.0 0.0 0.0 1.5 0.3 6.5 2.2 0.0 2.5 29.9 0.2 0.2 8.8 0.0 0.5 0.0 0.1 0.0 0.0 0.5 3.3 2.0 0.2 2.0 1.2 6.2 6.7 3.1 5.9 1.8 3.7 0.9 6.1 2.1 7.1 17.0 0.7 0.0 3.4 2.7 3.7 0.0 0.2 5.0 11.6 0.0 4.2 2.9 0.3 0.4 0.0 0.1 0.1 5.0 0.1 0.0 0.6 PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 778.3;Excitatory neurons: 244.9;Inhibitory neurons: 473.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "AN3-CA: 14.3;BJ hTERT+: 19.2;fHDF/TERT166: 16.1;U-138 MG: 11.2;U-87 MG: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 7.0 8.3 6.4 2.7 7.2 0.6 3.1 1.4 6.9 10.3 12.4 5.5 2.4 10.3 3.5 5.2 5.2 7.0 14.1 6.6 10.7 3.8 1.7 6.8 1.2 5.1 4.6 4.2 1.7 9.6 1.3 10.1 3.2 6.4 5.3 3.6 4.0 8.1 25.8 1.0 3.4 14.6 5.3 2.5 3.3 1.8 12.2 1.5 7.0 36.1 0.9 5.4 4.2 2.7 0.1 0.2 1.7 14.3 6.5 6.0 0.1 5.4 19.2 2.1 2.6 0.1 0.9 0.3 0.0 16.1 2.0 0.1 0.0 0.1 1.7 0.0 5.0 1.0 0.3 0.0 5.5 0.0 0.1 8.1 0.1 4.8 0.1 0.6 0.0 0.0 0.0 0.1 5.3 0.1 0.0 0.0 4.1 0.0 2.5 0.0 3.9 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 2.0 0.1 0.0 0.0 11.2 1.9 5.9 3.7 1.5 0.8 0.0 10.0 0.0 2.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.4 7.2 1.4 6.9 6.6 10.7 5.1 4.6 3.2 5.3 12.2 2.7 10.5 16.0 10.8 778.3 0.3 0.9 1.7 0.0 7.4 5.9 2.8 9.4 31.4 0.0 0.0 3.7 0.0 1.0 0.3 2.9 0.0 2.4 56.0 0.4 14.7 7.1 0.0 3.4 244.9 3.6 1.2 24.2 0.5 0.5 4.5 0.1 5.0 0.0 0.4 0.0 473.0 4.2 0.0 0.0 2.2 53.0 32.6 5.3 3.6 188.3 0.0 23.6 0.0 24.6 8.0 4.8 14.1 39.5 0.1 0.5 3.2 0.2 0.9 1.3 39.5 3.9 69.9 0.9 0.9 1.6 0.6 2.2 0.2 7.9 3.6 1.0 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PROB1 C5orf65 ENSG00000228672 "Proline rich basic protein 1" E7EW31 5 139390592-139395104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.3;skeletal muscle: 81.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "HDLM-2: 104.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA053354, HPA060103" Enhanced Enhanced Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA053354: , HPA060103: AB_2684205" "unprognostic (4.14e-2)" "prognostic favorable (9.26e-4)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.53e-2)" "unprognostic (9.27e-3)" "unprognostic (4.72e-2)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "unprognostic (3.21e-2)" "unprognostic (4.84e-4)" "unprognostic (7.10e-2)" "unprognostic (1.75e-2)" "unprognostic (9.05e-2)" "unprognostic (3.62e-2)" "unprognostic (5.89e-2)" "unprognostic (8.24e-2)" 1.4 4.8 4.2 0.9 3.3 0.4 1.5 3.5 2.5 1.4 2.2 1.9 1.2 1.7 0.4 1.0 2.1 0.4 23.3 3.3 4.5 1.7 0.6 0.9 1.0 6.4 7.8 0.6 0.4 2.3 2.9 0.6 4.9 3.3 0.1 0.3 2.4 1.3 81.0 0.7 1.6 0.5 6.1 1.6 1.2 0.8 5.0 0.7 1.0 18.4 0.6 1.6 1.0 2.9 1.5 0.6 0.3 0.3 0.1 0.3 0.5 1.2 0.3 1.3 1.1 4.3 2.6 5.7 1.1 3.9 0.1 0.7 0.5 0.1 0.3 104.7 1.4 1.4 2.7 0.5 3.0 0.0 3.2 0.9 0.7 2.8 0.6 0.7 0.1 3.7 0.5 5.7 4.1 1.2 4.9 2.6 1.4 0.6 2.7 15.4 0.4 12.5 0.2 0.1 1.3 0.7 6.0 4.5 0.2 1.3 2.1 3.0 0.4 0.1 0.4 0.2 0.4 1.0 1.8 9.2 0.1 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.2 3.3 3.5 2.5 3.3 4.5 6.4 7.8 4.9 6.1 5.0 2.9 2.4 0.0 0.0 0.0 0.7 0.0 0.3 0.0 1.2 0.0 0.4 0.1 29.7 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.2 2.4 1.5 2.5 0.0 0.4 0.0 0.0 0.3 1.2 1.1 0.9 0.0 0.7 2.9 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.3 0.1 1.2 3.0 0.3 0.0 2.4 0.0 0.2 6.6 5.6 2.9 0.4 0.8 0.3 0.0 2.6 0.4 2.4 0.6 0.3 PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 107.5;heart muscle: 116.6;liver: 283.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 83.1;Hepatocytes: 307.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 112.3;ASC TERT1: 100.1;HSkMC: 78.2;SK-MEL-30: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" NA NA 22500000000 5000000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" 33.6 8.7 1.7 8.1 1.3 0.3 24.7 1.6 2.7 14.9 107.5 17.3 13.5 16.4 2.0 16.6 19.4 33.7 116.6 3.2 2.2 37.7 283.1 39.2 4.7 2.1 2.4 32.6 5.6 13.5 8.5 32.0 2.2 8.4 21.6 4.6 12.3 10.3 4.9 20.5 20.6 19.2 1.6 11.2 10.5 5.0 2.3 1.5 17.0 16.9 3.7 18.5 15.1 1.7 0.4 2.7 3.0 27.1 112.3 100.1 1.6 4.6 9.4 1.0 6.6 12.7 1.4 0.0 30.0 3.0 18.8 0.0 1.4 0.9 1.8 0.1 7.3 51.4 1.4 29.8 8.7 1.5 1.2 78.2 0.4 4.0 0.6 63.0 7.2 3.7 32.8 0.1 49.2 0.0 0.1 0.0 3.1 2.7 6.5 0.3 1.2 0.0 27.7 0.0 7.6 19.8 5.0 0.0 157.0 0.6 0.0 19.9 9.4 14.8 2.8 8.2 1.7 0.0 0.0 0.0 60.4 30.4 27.8 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 3.2 1.7 1.3 1.6 2.7 3.2 2.2 2.1 2.4 2.2 1.6 2.3 1.7 55.9 64.1 33.8 17.9 1.9 14.8 3.6 2.1 4.0 0.5 1.7 14.0 44.6 14.3 7.5 1.8 10.4 0.6 0.5 7.5 3.9 9.8 3.2 2.1 30.7 47.1 15.7 16.4 28.4 4.4 0.7 83.1 2.0 1.1 30.9 5.0 65.7 307.1 12.8 1.7 19.7 11.6 0.0 31.5 20.6 6.3 28.6 14.6 19.6 27.2 1.3 22.8 0.0 10.6 4.6 5.6 19.3 36.9 0.3 4.5 1.9 42.2 56.6 8.1 13.1 32.4 28.4 0.4 0.7 11.8 33.2 1.6 2.1 10.8 12.6 2.3 PRPH "NEF4, PRPH1" ENSG00000135406 Peripherin P41219 12 49293252-49298686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.6;intestine: 21.0" "Group enriched" "Detected in some" 6 "Early spermatids: 327.5;Late spermatids: 920.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 1.6;glioma: 1.7;pancreatic cancer: 1.1;testis cancer: 1.5" "Group enriched" "Detected in many" 5 "medulla oblongata: 51.9;pons: 53.6;white matter: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 367.0" "Group enriched" "Detected in many" 4 "hypothalamus: 19.4;pons and medulla: 35.1" "Region enriched" "Detected in many" 8 "spinal cord: 256.8" "CAB002437, HPA039277, HPA063887" Enhanced NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "CAB002437: AB_563956, HPA039277: AB_2676424, HPA063887: AB_2685142" "unprognostic (1.73e-2)" "unprognostic (3.03e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.88e-4)" "unprognostic (5.04e-3)" "unprognostic (1.88e-2)" "unprognostic (6.29e-2)" "unprognostic (1.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.38e-2)" "unprognostic (1.24e-1)" "unprognostic (4.25e-3)" "unprognostic (3.63e-2)" "unprognostic (5.73e-2)" "unprognostic (4.86e-3)" "unprognostic (6.36e-5)" 3.1 14.5 0.9 7.5 1.1 0.0 1.8 0.3 1.8 3.3 0.4 21.0 4.7 0.8 0.1 0.5 3.1 0.6 1.2 0.9 2.2 0.9 0.1 0.9 0.2 51.9 8.0 0.7 1.3 0.1 2.9 0.3 53.6 2.3 2.1 1.5 0.5 1.5 0.4 1.1 8.9 2.0 7.8 1.2 5.2 13.2 0.9 0.1 0.5 0.2 0.1 1.5 8.3 15.7 0.0 0.7 0.0 367.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.7 1.6 0.4 1.3 0.2 0.2 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 3.7 0.0 0.2 2.0 0.0 2.2 0.4 0.0 1.6 86.6 1.5 0.2 0.8 0.0 0.0 1.7 0.1 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.3 1.8 0.9 2.2 51.9 8.0 53.6 7.8 0.9 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 10.8 0.3 0.8 0.4 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.0 327.5 0.5 0.1 1.4 92.3 0.0 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 25.2 0.1 1.0 0.0 0.0 0.9 920.2 5.9 0.7 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.8 0.1 38.1 0.0 0.1 14.1 96.1 19.4 0.3 0.4 0.0 0.1 0.0 0.5 0.2 PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 28.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.2;Proximal enterocytes: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.9;OE19: 18.0;RT4: 11.7;SK-BR-3: 13.3;T-47d: 14.4;U-266/84: 18.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" 1.2 0.4 0.9 1.2 0.9 0.1 7.0 1.3 2.6 4.9 0.6 8.4 12.0 1.5 12.9 13.5 4.9 4.3 1.2 0.9 1.0 11.8 6.4 3.9 0.9 1.2 0.9 0.3 13.1 28.4 15.6 2.1 1.1 6.2 7.7 0.1 11.3 9.0 0.9 12.9 11.0 1.1 0.9 1.0 9.8 0.9 1.1 2.3 13.4 0.1 3.9 6.7 5.5 1.0 11.1 0.4 0.3 0.9 1.3 0.0 4.6 0.2 0.0 0.4 0.4 2.2 14.9 0.7 1.6 0.1 0.3 8.5 0.3 8.5 0.4 1.1 1.2 0.5 0.8 0.7 0.9 0.4 1.1 0.9 7.4 0.3 0.3 0.7 3.4 0.9 0.2 0.8 0.0 2.4 0.2 0.7 0.6 18.0 1.4 0.2 0.3 8.7 6.5 11.7 2.4 0.3 1.3 13.3 0.1 1.0 14.4 0.2 0.6 0.8 0.7 0.4 0.1 5.1 18.7 0.5 0.2 0.3 0.4 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.1 0.1 0.0 0.1 0.2 0.2 0.5 0.0 0.2 1.2 0.2 0.1 0.9 0.9 1.3 2.6 0.9 1.0 1.2 0.9 1.1 0.9 1.1 1.0 6.4 6.4 13.4 0.7 3.4 4.1 11.6 20.2 29.6 2.2 21.5 22.6 0.9 8.6 14.2 12.9 2.1 13.0 4.1 47.2 3.9 31.9 0.7 10.8 4.1 6.4 16.2 1.3 0.5 33.2 6.5 1.6 16.8 16.1 2.5 2.3 1.1 6.8 2.3 5.0 0.4 18.0 8.2 1.9 1.2 0.4 0.3 3.3 1.8 1.9 8.2 0.9 2.1 2.0 0.4 27.4 29.4 0.0 4.4 14.5 46.3 15.5 8.8 4.1 0.0 0.8 3.9 1.9 2.1 23.3 4.7 12.7 4.1 4.6 20.7 14.6 PRRG4 TMG4 ENSG00000135378 "Proline rich and Gla domain 4" Q9BZD6 11 32829927-32858120 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 124.3;Basal squamous epithelial cells: 145.1;Prostatic glandular cells: 153.9;Squamous epithelial cells: 141.8;Suprabasal keratinocytes: 141.5;Urothelial cells: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 11.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.9" "Cell line enhanced" "Detected in many" "HaCaT: 52.7;hTCEpi: 28.0;SK-BR-3: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA009040, HPA024566" Uncertain Approved "Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA009040: AB_1079694, HPA024566: AB_2237712" "unprognostic (3.30e-1)" "unprognostic (3.68e-2)" "unprognostic (1.14e-1)" "unprognostic (6.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.45e-2)" "unprognostic (2.06e-1)" "unprognostic (4.13e-1)" "unprognostic (3.24e-2)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (2.26e-3)" "unprognostic (3.16e-2)" "unprognostic (1.99e-1)" "unprognostic (2.41e-1)" "unprognostic (1.26e-2)" 1.1 1.6 0.7 2.0 0.9 4.6 7.2 0.7 0.8 7.5 2.1 6.9 7.5 1.4 6.1 23.4 5.4 3.4 1.3 0.7 1.5 13.3 22.6 6.4 1.1 1.1 0.9 0.3 3.9 2.9 2.8 5.8 1.1 6.3 6.3 0.2 10.0 6.0 1.1 20.8 7.4 0.9 0.7 3.0 5.4 0.5 1.0 3.6 5.5 1.4 6.6 6.8 13.7 1.3 13.2 0.4 0.1 0.1 0.3 0.0 5.4 0.1 6.5 1.5 2.6 6.2 12.7 0.1 0.4 0.0 3.3 52.7 1.3 3.2 0.4 0.4 8.7 2.7 1.8 0.4 0.0 0.9 2.4 0.4 28.0 0.5 0.1 2.2 0.0 0.0 0.0 0.7 0.5 5.9 1.1 6.0 0.6 10.7 1.5 0.1 0.0 1.6 9.6 16.5 1.8 0.1 8.8 22.0 2.8 1.6 16.0 12.8 0.1 0.6 0.8 2.9 1.3 5.8 4.3 0.1 1.6 7.5 2.5 0.8 2.3 0.1 0.1 0.8 0.1 0.1 0.1 0.1 0.5 0.2 0.1 0.1 11.9 0.2 0.8 0.2 0.1 0.5 0.7 0.9 0.7 0.8 0.7 1.5 1.1 0.9 1.1 0.7 1.0 1.3 4.2 28.9 23.0 1.0 2.8 124.3 92.5 53.6 145.1 0.1 43.0 21.1 1.0 95.8 33.9 47.8 0.0 24.4 1.7 46.8 7.9 31.5 0.7 75.5 7.4 10.2 13.8 2.5 0.3 36.3 16.8 3.6 25.0 81.9 0.0 6.0 8.9 57.1 8.1 1.7 0.3 34.7 24.4 50.0 15.4 0.3 0.3 12.6 12.4 4.7 40.2 0.1 0.0 1.0 0.1 26.4 19.5 1.5 6.9 153.9 48.3 21.4 51.1 0.2 6.6 2.5 8.8 2.4 4.1 141.8 141.5 82.0 2.6 0.2 47.0 167.4 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 753.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046007, CAB046008, HPA047266" Approved NA NA 22000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "CAB046007: AB_11128404, CAB046008: AB_2171861, HPA047266: AB_2680006" "unprognostic (1.49e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-1)" "unprognostic (6.57e-3)" "prognostic unfavorable (2.54e-5)" "unprognostic (8.82e-2)" "unprognostic (1.87e-2)" "unprognostic (5.06e-3)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (7.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.21e-2)" "unprognostic (6.31e-2)" "unprognostic (1.98e-2)" 223.2 200.1 127.6 148.5 132.0 260.4 198.0 136.9 146.2 134.6 127.1 180.3 132.2 163.4 102.9 191.0 140.5 91.3 266.2 131.9 137.0 168.9 214.0 170.3 164.9 134.0 131.7 134.4 140.2 114.1 104.1 115.0 136.7 117.8 108.0 54.5 129.2 104.2 753.9 136.6 151.3 117.1 134.7 163.3 152.9 61.3 136.4 188.0 121.9 375.3 155.4 168.2 141.3 143.7 532.8 674.6 390.9 419.4 357.2 277.8 345.0 398.3 343.6 1024.7 428.8 1785.8 504.0 438.2 926.2 421.0 644.1 627.2 371.9 752.5 497.0 261.0 261.1 1009.7 641.9 913.2 454.0 434.3 570.4 297.9 602.0 525.1 454.5 248.8 509.2 436.1 439.2 419.2 441.8 568.6 696.1 673.6 332.5 595.0 859.8 476.9 753.5 482.6 385.3 515.4 526.2 321.6 625.9 777.1 701.9 252.7 468.3 643.3 416.1 898.9 725.4 473.3 631.1 286.9 483.9 531.2 626.7 327.7 536.1 754.4 682.6 801.5 536.5 692.6 458.2 579.3 533.3 531.4 632.2 522.7 415.1 427.3 582.2 421.7 720.3 676.3 723.4 1131.2 127.6 132.0 136.9 146.2 131.9 137.0 134.0 131.7 136.7 134.7 136.4 143.7 402.9 211.5 180.8 20.9 252.3 374.5 350.6 616.4 167.4 127.5 223.0 296.4 304.9 327.5 369.2 257.5 73.0 666.2 309.5 375.2 498.9 581.9 355.5 290.2 345.4 397.3 232.0 439.4 19.2 727.7 775.7 321.9 132.0 276.5 251.4 304.7 335.5 787.5 807.0 82.4 18.4 325.6 453.7 435.7 453.1 211.0 334.6 414.8 368.2 18.7 598.4 219.3 377.9 15.1 28.9 663.3 386.4 293.8 234.5 639.7 455.1 759.6 288.8 122.5 230.1 237.0 659.7 81.4 126.3 291.9 309.3 852.6 310.4 410.0 386.9 438.7 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 66.2;Cardiomyocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 146.8;WM-115: 111.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" 11.6 21.1 3.2 10.1 3.5 0.0 10.6 3.3 4.8 14.9 8.3 40.6 11.3 31.2 10.6 21.2 23.9 17.2 48.8 3.3 2.6 4.0 6.6 6.6 2.5 2.8 4.5 15.9 13.3 6.3 2.9 5.0 2.2 18.0 21.7 1.4 18.5 23.6 2.9 17.8 14.0 46.6 4.6 3.1 10.5 5.3 4.1 5.3 6.9 3.9 6.2 20.1 15.1 3.2 40.0 10.3 18.4 42.8 3.2 8.3 2.6 2.8 4.4 15.4 5.8 7.2 8.7 0.0 35.7 10.6 12.7 69.7 41.4 74.4 9.7 0.4 25.1 2.9 24.0 11.1 1.1 0.1 3.9 37.3 66.0 2.0 36.4 21.9 30.0 4.2 16.5 0.2 23.5 50.9 0.0 5.5 21.5 3.3 0.1 0.0 100.6 0.2 51.3 32.4 9.0 20.8 80.0 55.9 22.9 32.1 48.8 12.3 77.6 22.4 33.2 37.2 25.1 0.0 0.1 0.1 146.8 0.0 111.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 3.5 3.3 4.8 3.3 2.6 2.8 4.5 2.2 4.6 4.1 3.2 2.3 3.2 5.9 15.0 0.5 66.2 13.4 25.6 22.2 6.5 10.9 11.9 79.4 10.0 12.2 3.7 0.0 0.8 0.3 20.6 1.9 31.2 4.8 10.2 19.3 12.1 13.9 0.0 13.6 31.8 5.5 32.0 10.7 16.9 0.0 22.1 3.9 11.1 4.4 0.0 7.4 18.2 14.2 8.8 9.7 6.3 19.3 4.7 8.8 3.7 3.1 1.2 0.0 31.2 0.9 27.9 11.1 30.1 0.0 15.1 15.8 1.2 13.6 0.2 19.7 48.5 12.5 0.8 5.2 20.3 45.3 0.8 1.4 28.3 26.3 17.4 PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.7;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in many" "B-cells: 46.8;dendritic cells: 112.7;granulocytes: 140.7;NK-cells: 99.9;Plasma cells: 63.9;T-cells: 127.2;Theca cells: 54.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 9.8" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "granulocytes: 24.9;NK-cells: 14.9;T-cells: 14.0" "Cell line enhanced" "Detected in some" "HEL: 54.1;HL-60: 118.6;HMC-1: 150.8;NB-4: 51.4;THP-1: 53.7;U-937: 84.0" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in many" 8 "basal ganglia: 13.3" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Microtubules, Mitotic spindle" "CAB009530: AB_2173845, HPA019118: AB_1855755" "unprognostic (4.19e-3)" "unprognostic (1.08e-3)" "unprognostic (3.09e-2)" "prognostic favorable (1.52e-4)" "unprognostic (2.91e-2)" "prognostic favorable (1.84e-4)" "unprognostic (3.01e-2)" "unprognostic (3.16e-2)" "unprognostic (1.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.42e-8)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" 1.3 4.2 0.6 10.2 9.8 39.7 0.7 1.0 1.8 0.8 0.5 2.2 4.5 1.1 0.0 1.5 0.6 3.2 0.5 0.6 1.2 1.3 1.1 2.5 20.8 2.3 1.5 0.3 0.4 0.1 0.3 0.5 1.8 0.8 2.7 0.0 1.3 0.6 0.1 1.2 5.6 1.5 1.4 9.9 2.4 8.3 2.9 31.1 0.8 0.5 20.8 3.2 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.6 0.0 54.1 0.0 0.0 0.0 118.6 150.8 0.0 0.0 0.0 0.0 0.0 0.1 40.0 2.3 5.0 0.0 0.0 16.3 51.4 0.0 0.0 0.0 2.4 0.0 39.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 53.7 0.3 0.0 0.5 0.0 0.1 22.8 6.3 33.7 0.1 84.0 0.1 17.9 1.5 24.9 13.7 1.5 12.5 2.6 9.2 14.0 2.9 3.2 6.7 8.2 9.9 14.9 0.6 3.8 12.8 4.5 0.6 9.8 1.0 1.8 0.6 1.2 2.3 1.5 1.8 1.4 2.9 2.5 3.2 3.2 5.1 3.3 46.8 2.3 1.3 0.1 0.0 2.7 1.5 1.8 0.7 1.5 0.7 0.0 0.0 0.5 112.7 0.5 0.0 0.5 0.6 0.9 0.8 5.6 0.0 35.5 0.7 0.0 0.2 2.2 1.5 0.7 140.7 6.7 3.6 0.4 15.4 0.0 0.7 0.1 0.0 11.2 31.2 2.4 5.3 21.3 8.8 1.0 10.4 3.8 99.9 1.0 4.6 0.1 0.1 2.2 63.9 0.6 0.2 0.7 0.1 3.7 0.0 0.9 1.1 0.8 0.7 0.5 2.4 0.8 127.2 54.6 0.5 0.6 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Group enriched" "Detected in many" 12 "Excitatory neurons: 4579.7;Inhibitory neurons: 1152.9;Oligodendrocyte precursor cells: 1170.2;Oligodendrocytes: 3151.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.1;HAP1: 4.3;HSkMC: 6.3;RH-30: 8.1;SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.1 0.6 10.8 0.3 24.7 0.1 0.9 12.2 26.2 5.6 0.0 3.3 1.8 2.4 0.2 0.6 2.2 1.0 2.5 14.4 7.2 6.6 3.6 4.6 0.0 14.6 10.1 12.1 1.3 18.7 4.3 5.3 19.1 1.9 2.5 6.4 0.5 0.6 0.9 0.7 5.0 1.0 10.4 0.4 0.9 1.6 17.6 0.7 3.4 0.8 0.0 2.2 3.4 70.8 0.0 0.1 21.1 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.7 3.6 0.5 0.0 0.0 0.0 0.1 6.3 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.6 0.0 3.4 0.0 3.2 2.3 8.1 0.0 1.8 0.0 4.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.7 12.2 26.2 14.4 7.2 14.6 10.1 19.1 10.4 17.6 70.8 0.5 0.0 3.2 199.2 0.1 0.5 0.4 3.2 6.2 134.2 0.3 0.1 6.5 27.1 1.8 5.5 16.7 0.3 0.0 16.4 0.0 3.6 15.8 0.8 15.0 1.2 35.4 0.0 4579.7 0.0 0.3 15.5 0.5 1.0 0.0 9.2 1.4 13.5 1.3 5.0 1152.9 13.2 0.0 0.8 0.0 6.5 15.8 1.6 0.0 85.3 0.1 36.1 0.0 1170.2 3151.1 0.2 9.2 0.0 2.7 2.1 18.3 26.3 0.2 7.8 0.0 4.0 5.8 2.4 3.2 0.4 0.9 0.3 0.8 6.0 8.7 0.1 PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.8;kidney: 36.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 193.6;Inhibitory neurons: 231.1;Oligodendrocyte precursor cells: 126.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 9.9;NTERA-2: 5.8;SH-SY5Y: 6.1;THP-1: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" 1.8 0.8 8.7 3.0 9.4 0.2 0.8 0.0 10.3 1.3 0.1 10.4 1.7 4.8 1.4 0.4 1.0 1.2 0.5 9.8 8.9 36.3 1.3 6.8 3.1 2.2 3.3 0.4 0.4 0.3 2.4 4.4 5.3 0.5 26.8 7.5 0.5 0.8 0.3 0.4 2.0 6.6 0.9 3.4 0.8 0.5 9.5 1.2 0.3 0.5 3.2 1.5 0.4 2.9 0.0 0.1 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.5 1.3 0.0 0.0 0.1 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.8 1.2 0.0 0.0 0.0 0.0 0.1 0.2 1.5 6.1 0.9 0.0 0.1 0.1 0.1 2.7 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.3 0.0 0.1 1.2 0.0 6.0 0.0 0.0 12.3 0.0 8.9 1.7 0.4 8.5 8.6 2.8 1.2 0.1 0.1 12.7 10.9 1.4 3.2 8.7 9.4 0.0 10.3 9.8 8.9 2.2 3.3 5.3 0.9 9.5 2.9 0.2 0.0 0.5 7.5 7.0 0.3 1.3 0.5 0.0 25.2 0.0 0.1 0.7 0.0 1.8 16.5 0.0 0.2 4.0 3.9 0.0 0.4 0.0 0.8 0.2 1.1 3.6 0.0 193.6 0.0 0.2 0.9 0.0 0.6 0.0 0.0 1.1 0.2 26.1 25.2 231.1 8.3 0.0 21.1 10.6 0.6 0.6 10.5 0.0 17.8 13.8 0.6 1.0 126.7 6.3 0.1 9.8 0.4 1.0 0.1 0.1 0.2 0.0 4.8 0.0 2.1 0.7 0.6 1.1 0.1 0.4 0.3 1.0 0.1 22.4 0.8 PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.8;Distal enterocytes: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 407.8;SK-MEL-30: 528.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" 50.8 36.4 78.2 27.7 77.9 14.1 61.1 84.1 82.4 37.0 35.4 140.9 27.0 51.9 21.4 106.6 37.8 39.1 163.9 77.3 74.9 43.7 14.6 32.1 19.1 85.4 80.8 25.9 25.4 18.1 61.5 11.5 81.2 107.9 72.6 25.4 125.1 106.3 18.7 85.3 44.8 59.8 84.7 22.6 51.3 25.2 80.3 18.4 45.2 10.5 17.3 154.2 53.0 84.8 31.5 220.1 39.1 38.3 97.9 182.7 28.7 62.2 80.9 51.4 43.0 50.1 38.0 37.1 71.8 83.6 96.1 123.9 44.5 165.8 27.9 21.1 27.5 29.5 18.6 86.9 115.7 44.7 40.0 107.1 152.4 130.5 191.3 63.5 66.6 23.0 16.5 91.4 73.0 87.1 45.1 34.6 35.2 38.2 407.8 33.7 71.0 49.8 280.5 56.8 58.4 36.5 42.7 74.0 528.7 31.0 51.9 28.4 147.4 60.3 36.5 65.1 128.7 35.2 58.8 14.4 67.9 34.8 335.3 4.6 14.1 7.1 10.2 19.4 9.9 5.4 8.1 9.2 14.5 4.6 10.3 12.9 3.3 11.2 23.4 7.1 9.6 23.4 78.2 77.9 84.1 82.4 77.3 74.9 85.4 80.8 81.2 84.7 80.3 84.8 10.0 9.6 34.6 43.1 8.7 11.9 23.1 20.7 22.2 35.8 31.6 43.6 122.8 11.5 14.6 25.8 37.5 7.1 10.7 185.2 11.7 17.6 3.5 12.7 17.2 13.5 28.2 8.6 22.9 16.5 7.2 15.3 40.2 21.6 6.3 16.2 8.9 5.8 10.8 18.5 26.9 47.3 57.0 13.8 10.7 9.2 27.4 18.5 35.6 15.0 16.6 21.3 15.5 11.6 19.1 27.0 68.5 86.5 22.9 17.6 20.9 11.1 11.9 9.3 0.0 13.5 23.1 2.0 8.5 15.3 10.1 4.4 12.9 20.3 72.0 9.7 RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.4;testis: 48.8" "Cell type enhanced" "Detected in many" "Early spermatids: 334.6;Horizontal cells: 212.0;Late spermatids: 1251.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.7" "Cell line enhanced" "Detected in many" "BEWO: 64.3;Daudi: 36.8;Hep G2: 40.6;HMC-1: 41.5;RT4: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" 0.9 1.1 68.9 8.1 72.0 15.0 4.1 48.9 71.4 2.7 22.0 9.3 12.9 1.2 11.2 6.7 7.5 3.2 2.7 66.2 47.6 6.8 2.9 5.7 11.8 55.3 66.0 2.4 17.6 6.1 3.5 10.5 51.7 2.5 7.3 7.7 7.4 3.8 0.5 8.1 14.7 0.9 54.3 7.4 13.4 48.8 70.7 4.6 4.6 0.4 10.7 5.1 2.1 78.4 12.4 1.4 1.3 3.2 0.5 0.0 64.3 0.2 0.0 0.8 0.8 20.7 1.9 36.8 4.6 0.2 13.3 10.3 12.2 5.9 0.5 7.5 11.0 0.0 0.5 40.6 0.3 2.7 41.5 0.3 5.9 0.8 2.6 0.4 0.0 10.9 2.7 0.9 0.0 9.8 2.7 0.7 10.5 22.9 0.4 1.0 0.1 7.1 2.3 37.8 19.1 13.9 2.8 17.4 14.6 8.7 25.7 1.2 0.0 0.7 6.3 0.1 0.6 6.6 5.6 3.4 0.2 3.7 2.5 5.5 8.4 78.7 13.9 11.9 8.7 5.8 7.2 10.3 5.4 8.6 7.6 9.1 40.5 6.4 15.8 1.1 9.6 8.7 68.9 72.0 48.9 71.4 66.2 47.6 55.3 66.0 51.7 54.3 70.7 78.4 0.6 6.4 8.3 15.7 12.1 3.1 11.4 5.7 1.8 9.6 9.1 5.2 7.3 15.7 9.6 11.0 10.4 73.1 19.8 32.6 13.7 17.5 334.6 39.0 3.9 1.5 14.9 2.7 68.6 28.2 10.9 2.3 17.3 48.8 12.0 7.3 1.1 4.4 6.0 212.0 71.0 16.0 12.2 1.9 5.7 1251.4 5.3 6.3 10.6 1.9 11.1 53.7 26.8 13.6 72.3 24.8 20.2 4.9 7.0 11.1 25.9 12.4 18.1 7.4 0.0 3.1 2.7 8.3 9.7 4.4 3.0 50.3 15.2 0.2 21.1 15.4 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 RAB37 ENSG00000172794 "RAB37, member RAS oncogene family" Q96AX2 17 74670578-74747335 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.5;brain: 20.8;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "dendritic cells: 33.4;Excitatory neurons: 33.2;granulocytes: 50.7;Inhibitory neurons: 29.6;NK-cells: 87.6;T-cells: 31.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 269.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.7" "Cell line enhanced" "Detected in some" "HEL: 50.6;HMC-1: 58.7;OE19: 25.4;U-266/70: 84.9;U-937: 34.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "unprognostic (2.10e-2)" "unprognostic (7.04e-4)" "unprognostic (5.95e-2)" "unprognostic (9.80e-4)" "unprognostic (3.49e-1)" "unprognostic (7.04e-5)" "unprognostic (1.74e-1)" "unprognostic (1.48e-2)" "unprognostic (7.62e-3)" "unprognostic (9.47e-3)" "unprognostic (3.05e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (8.80e-6)" "unprognostic (7.30e-2)" "prognostic unfavorable (9.27e-4)" "unprognostic (7.80e-2)" "unprognostic (4.01e-2)" 1.4 1.9 1.5 10.5 2.7 24.5 1.0 20.8 10.5 1.8 0.0 5.4 5.2 1.3 1.8 1.9 1.6 4.8 1.3 1.2 2.8 1.0 12.2 6.8 19.2 11.8 4.6 0.5 0.7 1.7 0.6 1.8 11.3 3.9 5.1 3.3 2.3 0.9 0.6 0.8 8.3 1.9 0.6 17.0 6.7 0.8 11.1 21.3 0.6 2.7 14.9 4.2 1.9 3.7 0.0 7.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 50.6 0.2 0.3 0.1 3.9 58.7 0.5 0.0 0.0 0.0 0.0 0.0 7.3 0.0 18.3 0.0 0.2 15.3 13.0 0.0 25.4 0.0 2.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 3.6 0.0 2.9 0.2 11.4 0.0 0.0 0.3 0.0 0.0 84.9 3.6 1.1 0.1 34.3 0.0 269.7 13.6 201.5 51.1 28.9 12.9 12.3 22.4 37.8 7.3 12.2 12.5 28.3 63.2 54.0 50.3 1.4 42.8 48.9 1.5 2.7 20.8 10.5 1.2 2.8 11.8 4.6 11.3 0.6 11.1 3.7 0.9 3.2 3.2 1.6 23.1 0.1 0.2 0.3 0.0 7.6 0.8 0.4 1.8 5.7 1.8 0.0 6.2 0.1 33.4 1.3 0.0 1.3 0.0 0.1 0.1 0.9 5.4 16.0 33.2 0.9 0.1 2.0 8.2 0.5 50.7 0.0 2.2 12.6 0.6 3.3 29.6 7.7 14.2 2.2 0.0 0.4 0.6 18.5 0.0 1.9 11.8 1.3 87.6 2.0 1.6 0.4 2.8 1.2 6.3 0.1 0.2 1.5 2.3 1.0 6.6 3.0 1.1 0.0 1.5 0.3 0.1 0.0 31.0 0.5 0.5 0.3 RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "bone marrow: 58.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.4;granulocytes: 14.5;monocytes: 2.3;Squamous epithelial cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cell line enhanced" "Detected in some" "HEL: 21.9;HL-60: 30.9;HMC-1: 88.9;NB-4: 76.7;THP-1: 30.1;U-937: 60.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA079390 Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA079390: " "unprognostic (8.86e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (9.56e-2)" "unprognostic (6.35e-4)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" "unprognostic (2.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.13e-3)" "unprognostic (3.03e-2)" "unprognostic (9.67e-3)" "unprognostic (5.79e-2)" 0.5 0.0 0.0 0.6 0.1 58.9 0.4 0.0 0.1 0.4 0.0 0.4 0.6 0.3 0.2 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.4 0.0 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 30.9 88.9 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 76.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 10.6 0.8 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 4.4 0.7 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 1.3 0.3 0.2 0.0 0.3 0.0 0.5 14.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.4 0.1 0.0 0.1 RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;breast: 2.5;parathyroid gland: 3.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 10.3;Oligodendrocytes: 3.3" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.5;HMC-1: 2.2;REH: 5.4;T-47d: 3.2;U-266/70: 2.1" HPA059131 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (8.62e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-1)" 0.1 0.6 1.4 0.1 2.2 0.0 2.5 0.7 1.9 1.9 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 1.3 1.6 0.1 0.0 0.0 0.0 1.2 1.2 0.1 0.0 3.6 0.2 0.3 1.3 1.7 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.7 0.5 0.0 0.9 1.6 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.1 0.5 3.2 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 0.7 1.9 1.3 1.6 1.2 1.2 1.3 0.7 1.6 3.6 0.1 0.0 0.0 0.3 0.1 0.8 0.3 0.3 0.0 0.0 0.9 0.1 10.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.1 1.7 1.0 0.0 0.0 0.7 0.0 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.3 0.4 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.0 0.6 0.7 0.0 0.1 0.0 0.0 0.6 1.4 1.4 1.3 0.0 1.1 0.5 0.1 0.1 0.1 0.3 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 335.7" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 378.4" "Group enriched" "Detected in all" 4 "granulocytes: 378.4;monocytes: 176.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 440000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026010: , HPA065232: AB_2685440" "unprognostic (5.16e-2)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-2)" "unprognostic (3.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.77e-2)" "unprognostic (4.15e-2)" "unprognostic (4.91e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (2.29e-2)" "unprognostic (8.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" 53.8 35.9 30.6 57.2 30.8 60.0 39.9 32.8 38.7 44.3 33.1 59.2 50.5 37.5 15.8 73.3 45.7 44.8 51.0 32.3 37.7 56.5 34.2 50.7 35.8 30.8 33.6 28.7 25.6 335.7 16.6 63.1 30.6 51.0 51.8 25.8 36.2 31.7 30.1 25.7 44.8 46.5 31.3 54.2 39.3 29.9 37.9 27.5 30.8 43.9 35.0 51.0 49.1 32.8 179.8 47.7 46.8 29.5 71.2 115.5 66.7 121.4 105.8 93.3 70.5 99.4 118.0 7.1 63.9 131.6 88.2 64.1 22.5 93.1 85.7 293.3 25.8 84.4 36.3 71.3 46.0 45.1 144.9 60.3 99.0 97.2 74.0 77.1 272.9 6.3 66.5 28.1 108.2 91.9 5.9 100.0 31.7 71.6 101.9 1.2 59.3 38.1 97.5 45.6 13.3 32.1 50.4 137.9 85.1 39.3 43.3 66.3 168.4 91.1 69.8 93.9 48.8 16.2 9.1 12.8 72.7 57.5 95.6 101.8 80.9 230.5 19.0 117.7 18.5 45.0 18.0 19.0 65.4 59.6 11.9 13.7 378.4 25.5 176.1 6.9 24.6 59.5 30.6 30.8 32.8 38.7 32.3 37.7 30.8 33.6 30.6 31.3 37.9 32.8 69.3 9.6 27.0 6.5 23.8 19.4 30.1 22.4 7.4 4.1 23.2 7.9 55.8 18.6 21.9 11.0 12.5 6.0 11.8 95.3 66.5 84.9 18.8 28.4 22.8 77.8 18.6 8.4 12.9 55.0 128.5 32.7 17.9 26.7 106.1 90.6 78.5 9.8 53.6 13.5 9.7 19.1 18.3 54.3 59.4 23.0 19.9 66.7 35.6 16.9 62.6 26.3 21.6 10.1 5.4 138.1 62.1 31.2 6.7 28.5 44.6 104.4 46.3 7.5 19.7 18.3 33.4 13.1 16.2 16.4 18.9 36.7 19.5 12.9 31.3 32.2 RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 108.2;Extravillous trophoblasts: 82.2;Hofbauer cells: 69.4;Syncytiotrophoblasts: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA041923: AB_10796467, HPA041948: AB_10797270" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" "unprognostic (5.30e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (3.63e-3)" "unprognostic (2.09e-2)" "unprognostic (4.72e-2)" "unprognostic (7.46e-3)" "unprognostic (9.57e-2)" "unprognostic (2.72e-2)" "unprognostic (9.47e-2)" "unprognostic (2.45e-1)" 12.9 14.8 10.9 16.4 11.4 30.1 26.1 12.9 14.8 16.6 11.6 18.4 14.5 18.2 30.1 24.1 19.5 13.4 14.8 11.6 12.2 16.8 24.2 13.0 23.0 11.6 11.3 20.6 16.4 18.8 12.9 25.9 11.3 18.0 19.3 19.9 18.2 15.2 29.1 21.5 13.4 16.8 11.6 14.1 19.0 15.6 11.1 23.3 18.2 20.2 28.9 20.8 15.6 11.6 34.1 44.7 44.3 27.1 23.5 15.9 32.7 33.7 33.5 37.6 30.4 49.4 42.9 16.8 45.8 29.2 45.4 37.9 77.1 32.4 40.6 42.0 49.7 52.7 22.7 58.7 33.3 38.0 44.9 34.9 61.4 30.6 38.5 28.7 23.6 28.5 62.8 33.9 39.8 35.7 29.5 48.3 52.0 45.0 21.1 33.4 38.2 26.0 49.0 64.6 41.1 42.0 34.6 36.7 87.0 71.5 58.6 47.9 16.8 27.5 34.9 26.1 48.8 53.1 104.0 41.8 25.2 50.7 34.5 138.6 59.2 98.2 47.9 57.0 51.8 64.8 54.1 52.3 56.1 61.1 53.9 53.4 117.4 70.4 62.8 51.6 69.9 65.9 10.9 11.4 12.9 14.8 11.6 12.2 11.6 11.3 11.3 11.6 11.1 11.6 18.3 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 82.2 10.0 0.0 0.0 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 92.9 2.7 0.0 0.0 0.0 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RAP1B "DKFZp586H0723, K-REV, RAL1B" ENSG00000127314 "RAP1B, member of RAS oncogene family" P61224 12 68610855-68671901 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.20e-1)" "unprognostic (1.47e-3)" "unprognostic (1.11e-1)" "unprognostic (1.20e-1)" "unprognostic (4.15e-2)" "unprognostic (7.23e-2)" "unprognostic (1.60e-3)" "unprognostic (1.48e-1)" "unprognostic (5.83e-2)" "unprognostic (1.80e-1)" "unprognostic (2.01e-2)" "unprognostic (2.86e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.08e-1)" "unprognostic (8.86e-2)" "unprognostic (7.86e-2)" "unprognostic (3.22e-1)" 156.1 107.5 48.2 166.5 53.4 277.9 118.2 55.8 64.2 89.8 62.5 126.4 84.2 120.2 69.7 86.3 78.7 129.7 67.9 49.5 60.0 107.3 141.1 134.9 211.8 58.3 53.5 69.3 78.8 74.1 52.0 133.0 59.7 85.1 111.5 57.6 70.0 135.9 49.5 73.5 121.0 146.4 52.4 153.3 104.4 89.6 55.6 162.5 89.1 57.3 181.1 198.1 83.8 66.2 199.9 133.1 153.2 131.2 317.6 253.1 140.2 414.9 252.1 269.5 203.5 178.9 130.2 280.0 232.8 580.5 124.2 113.4 146.5 202.9 379.8 496.2 125.7 725.2 156.7 120.9 370.8 282.0 407.1 254.8 203.3 289.5 346.0 218.6 298.7 232.1 261.2 445.6 272.0 127.9 265.4 361.7 173.9 86.8 191.3 235.8 181.9 211.1 204.9 488.3 59.6 93.3 209.1 124.8 206.1 174.7 160.3 327.2 330.4 243.0 108.9 275.6 229.9 227.1 452.4 342.3 224.7 191.8 212.3 399.1 215.4 205.7 340.1 407.0 221.2 154.1 206.1 297.6 196.2 140.3 222.2 303.4 149.8 469.5 464.3 99.0 186.2 820.8 48.2 53.4 55.8 64.2 49.5 60.0 58.3 53.5 59.7 52.4 55.6 66.2 210.9 80.1 79.9 41.1 166.2 294.4 72.4 150.9 70.6 14.0 73.3 61.0 14.7 37.1 108.9 80.9 22.9 35.5 373.9 176.1 109.5 157.9 99.6 78.5 154.3 132.4 189.5 104.7 45.0 130.8 75.2 123.4 52.0 119.6 147.8 60.5 85.3 32.7 78.5 33.7 46.8 93.5 95.6 111.3 437.6 44.6 38.8 273.1 188.5 105.9 257.3 28.6 362.5 45.8 67.8 186.0 215.6 36.5 228.4 61.4 72.3 182.2 104.0 23.3 6.6 40.3 204.8 46.3 50.2 78.9 297.8 154.5 256.9 123.2 92.2 92.4 RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 130.6;Astrocytes: 143.0;Collecting duct cells: 69.9;Endothelial cells: 53.0;Oligodendrocytes: 45.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 26.9;HUVEC TERT2: 12.1;NB-4: 14.3;RPTEC TERT1: 13.3;TIME: 12.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" 44.6 2.8 29.2 2.6 35.0 1.4 44.0 30.3 29.2 26.0 12.5 9.9 4.0 16.4 6.9 13.2 24.1 13.2 21.1 31.4 21.3 40.0 1.9 11.9 4.4 33.6 29.6 38.2 4.7 5.8 6.4 8.9 28.0 13.5 2.4 0.9 21.2 11.0 11.4 9.8 8.8 5.1 22.4 16.2 11.5 3.5 28.9 1.6 32.4 9.0 2.1 14.9 21.3 39.7 2.3 0.6 0.7 2.4 0.3 2.3 0.9 1.7 1.5 0.7 0.4 0.3 6.1 0.1 26.9 3.0 1.1 2.4 0.8 4.5 0.3 3.0 0.4 0.2 2.6 0.2 0.2 0.4 0.3 0.9 0.3 1.3 0.8 3.4 12.1 0.6 0.1 2.9 0.5 1.5 0.0 14.3 0.6 1.0 3.7 0.4 0.1 1.0 13.3 2.5 0.2 0.3 0.2 1.7 0.4 0.8 6.7 0.6 12.0 6.6 1.1 1.5 0.6 1.0 0.4 0.2 4.1 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.2 35.0 30.3 29.2 31.4 21.3 33.6 29.6 28.0 22.4 28.9 39.7 130.6 0.0 11.7 143.0 0.7 2.7 5.8 2.6 13.1 0.5 4.5 4.8 15.7 2.8 3.6 69.9 0.0 0.2 1.4 1.7 7.9 1.1 1.6 11.8 2.4 53.0 0.0 0.0 1.5 0.7 0.4 6.3 18.3 21.2 3.8 1.5 20.7 0.2 0.9 0.0 2.9 6.6 4.1 0.6 2.6 3.7 24.2 1.5 5.4 12.2 0.0 1.5 2.1 10.6 45.7 5.8 6.3 8.6 4.4 11.6 0.8 41.3 1.9 0.5 6.6 2.7 5.1 1.2 1.6 1.4 3.3 0.3 1.3 6.6 0.8 17.2 RASA3 "GAP1IP4BP, GAPIII" ENSG00000185989 "RAS p21 protein activator 3" Q14644 13 113977783-114132623 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 55.0;Horizontal cells: 60.6;NK-cells: 48.4;Plasma cells: 40.0;T-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 60.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046759 Uncertain NA NA 1400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA046759: AB_10959887" "unprognostic (3.41e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.75e-1)" "unprognostic (6.15e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-3)" "unprognostic (4.01e-2)" "unprognostic (3.92e-1)" "unprognostic (2.02e-1)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.99e-6)" "unprognostic (8.98e-2)" "unprognostic (8.16e-3)" "unprognostic (5.08e-2)" "unprognostic (4.11e-2)" 32.2 3.5 7.6 10.9 8.7 12.7 23.2 6.5 9.8 24.4 3.8 17.0 2.9 13.7 1.1 4.9 19.2 4.6 12.9 8.5 8.3 11.2 5.0 19.3 15.6 9.6 8.9 7.6 10.8 0.7 15.2 5.3 9.3 11.3 2.7 2.6 6.8 3.6 14.2 13.0 15.8 4.7 8.0 22.6 9.4 5.9 10.0 9.0 14.4 4.2 7.7 18.5 15.0 14.6 3.8 4.6 20.2 5.8 19.2 21.3 0.0 14.8 22.1 13.1 10.9 0.4 11.6 0.4 8.2 24.1 10.9 0.0 3.0 7.0 10.1 0.9 1.3 29.4 14.1 0.1 9.7 12.3 2.5 19.2 1.4 12.7 9.1 16.2 22.3 0.6 2.2 3.3 19.9 5.1 27.1 20.5 4.3 3.2 6.8 13.6 7.4 60.6 11.9 0.1 2.9 2.1 3.5 15.2 7.5 8.3 3.8 44.7 30.5 19.7 5.4 7.2 16.2 0.1 0.0 0.8 25.7 11.9 32.1 16.7 4.5 6.4 16.9 7.6 12.8 5.2 15.6 17.0 3.0 3.9 16.3 16.4 2.5 12.7 15.3 1.0 19.2 16.9 7.6 8.7 6.5 9.8 8.5 8.3 9.6 8.9 9.3 8.0 10.0 14.6 5.3 0.0 4.2 27.1 20.6 3.7 1.2 0.7 2.2 7.9 2.0 4.6 7.5 1.5 3.5 1.8 0.0 0.1 55.0 0.3 0.0 1.1 1.5 7.8 13.3 9.3 3.0 5.5 25.6 2.0 0.2 15.2 3.6 5.1 26.0 1.8 3.9 2.4 9.3 60.6 12.2 2.6 2.0 15.1 12.1 0.7 8.7 19.6 10.6 36.5 11.4 1.3 48.4 17.6 27.5 12.5 0.2 3.8 40.0 1.6 0.1 0.4 13.2 3.5 0.0 18.9 11.5 8.6 5.4 0.4 4.8 0.5 45.2 2.5 0.7 1.6 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 220.6;Inhibitory neurons: 407.6;Microglial cells: 89.0;Oligodendrocytes: 395.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cell line enhanced" "Detected in some" "BEWO: 37.8;CACO-2: 23.3;Hep G2: 31.8;HHSteC: 20.8;hTERT-RPE1: 15.3;SuSa: 16.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 24.5;cerebral cortex: 77.3;hippocampal formation: 46.6;olfactory bulb: 27.0" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" 11.2 0.9 10.5 3.4 9.4 1.0 7.3 1.2 14.9 3.4 16.1 2.9 1.8 2.4 0.8 1.3 2.2 5.2 5.4 11.6 4.8 4.8 0.5 3.3 3.5 3.4 2.2 17.6 1.0 2.3 4.1 10.2 2.5 3.6 1.4 22.9 1.5 1.5 2.7 1.1 2.4 2.6 5.1 2.2 1.8 2.0 13.8 1.5 4.7 6.8 2.8 3.4 2.4 10.0 0.0 2.1 0.5 0.3 0.0 0.0 37.8 0.7 9.3 0.4 0.4 23.3 0.0 0.4 11.9 0.0 0.2 0.6 0.0 0.0 1.2 0.6 4.0 0.2 0.3 31.8 20.8 0.0 0.0 1.0 0.1 8.8 0.1 15.3 0.2 0.5 0.0 0.1 0.0 0.3 0.3 0.2 4.5 0.0 0.1 0.2 4.5 0.1 1.4 0.0 0.4 0.5 0.1 0.0 0.3 16.2 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.4 0.0 0.0 0.0 1.9 0.0 5.2 0.0 2.6 1.5 0.0 0.0 4.2 3.0 0.0 0.0 0.0 0.0 0.7 1.0 10.5 9.4 1.2 14.9 11.6 4.8 3.4 2.2 2.5 5.1 13.8 10.0 45.3 0.0 1.1 10.1 0.6 1.7 0.3 0.1 0.0 15.9 0.2 0.3 5.2 0.0 0.6 9.2 58.4 1.1 2.2 0.2 0.0 0.4 10.2 1.3 0.3 23.7 0.0 0.0 220.6 0.0 26.9 2.5 0.5 1.1 0.0 0.2 5.3 0.1 1.1 1.7 407.6 0.5 0.0 0.3 0.8 3.0 0.9 0.5 1.8 89.0 0.2 3.7 6.2 8.5 395.6 0.7 1.2 9.1 0.9 0.3 1.0 2.1 0.0 42.1 0.0 1.5 0.9 6.7 1.6 0.3 0.6 0.8 7.5 4.1 1.3 0.5 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASL12 RIS ENSG00000103710 "RAS like family 12" Q9NYN1 15 65053337-65076690 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 22.5;Peritubular cells: 57.9;Sertoli cells: 98.6;Smooth muscle cells: 55.7" "Cancer enhanced" "Detected in all" "glioma: 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;CACO-2: 14.5;EFO-21: 22.7;NTERA-2: 9.9;SuSa: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (6.13e-3)" "unprognostic (1.06e-1)" "unprognostic (2.47e-2)" "unprognostic (6.95e-2)" "unprognostic (1.39e-1)" "unprognostic (1.21e-2)" "unprognostic (4.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-3)" "unprognostic (1.60e-1)" "unprognostic (4.45e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (1.76e-2)" "unprognostic (4.72e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.17e-4)" 27.9 3.9 32.9 5.1 36.8 0.0 15.7 30.8 24.4 49.8 8.5 35.6 3.6 61.6 27.9 19.2 54.7 13.2 53.4 26.0 38.4 6.9 1.1 38.4 3.3 39.4 57.4 16.5 2.4 1.8 7.0 17.0 38.0 52.5 6.7 3.3 8.0 76.4 37.1 12.1 9.4 33.0 38.8 9.6 7.7 15.6 66.1 0.9 8.4 20.6 1.7 40.2 33.5 32.6 0.1 0.1 0.2 0.0 0.6 5.0 0.2 0.0 0.5 0.0 0.0 14.5 0.1 0.0 22.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 9.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 17.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.9 36.8 30.8 24.4 26.0 38.4 39.4 57.4 38.0 38.8 66.1 32.6 7.4 0.0 0.0 22.5 0.0 1.5 3.9 0.0 0.0 0.3 2.0 5.6 16.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 4.7 0.3 12.6 3.6 0.0 0.0 0.1 0.0 0.1 15.2 0.5 0.5 0.0 12.3 1.4 0.1 0.3 0.0 0.1 0.0 2.0 0.0 1.3 3.9 13.1 0.2 0.0 2.8 0.0 17.9 0.0 0.0 0.0 0.1 0.0 57.9 0.0 0.4 0.5 0.0 0.0 0.8 98.6 0.9 55.7 0.7 1.1 0.4 0.1 0.3 0.2 0.4 0.2 0.1 RASSF7 "C11orf13, CFAP88, FAP88, HRAS1, HRC1" ENSG00000099849 "Ras association domain family member 7" Q02833 11 560404-564025 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 127.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.6;Intestinal goblet cells: 179.2;Paneth cells: 194.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.5;HaCaT: 86.4;SK-BR-3: 75.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA078015 Supported "Centriolar satellite" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite" "HPA078015: AB_2686875" "unprognostic (1.11e-2)" "unprognostic (5.10e-2)" "unprognostic (1.75e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (1.13e-1)" "unprognostic (2.46e-3)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.60e-1)" "unprognostic (2.55e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.99e-1)" "unprognostic (2.83e-1)" "unprognostic (3.58e-3)" 15.6 5.0 7.1 8.5 9.4 6.5 13.8 10.1 10.4 23.4 6.8 50.5 33.6 6.3 15.8 49.2 50.9 10.8 4.9 7.3 7.1 127.5 92.8 44.6 10.7 9.3 6.5 6.6 67.5 6.4 27.4 5.0 9.9 42.6 8.5 1.6 42.5 11.5 1.6 53.5 43.5 1.0 6.4 17.7 63.5 13.2 7.1 8.7 23.3 0.6 5.6 18.6 23.7 6.3 51.7 49.9 2.3 12.8 0.0 0.0 35.2 7.7 5.9 8.0 5.9 52.6 85.5 6.6 34.6 4.2 14.0 86.4 7.3 26.5 1.2 8.9 25.6 4.6 28.0 25.9 5.3 10.8 7.4 0.1 25.5 2.7 2.4 11.0 4.8 13.4 11.7 2.5 0.7 51.7 12.2 23.1 7.1 58.2 28.1 19.2 3.7 14.8 39.2 24.8 10.9 8.4 5.4 75.7 6.6 4.0 34.0 6.9 6.6 1.6 23.5 3.1 15.0 8.6 9.9 5.3 12.8 15.1 6.9 5.2 6.0 23.0 17.7 5.2 16.1 13.6 18.3 15.9 10.5 14.8 14.8 13.2 7.3 8.3 5.7 18.7 21.9 8.9 7.1 9.4 10.1 10.4 7.3 7.1 9.3 6.5 9.9 6.4 7.1 6.3 6.5 86.6 70.0 3.3 19.1 25.4 23.4 118.1 14.2 2.7 39.2 30.6 4.7 92.9 90.4 86.5 0.0 38.9 20.9 224.6 52.8 90.7 17.2 28.8 3.9 8.5 51.0 14.5 5.5 90.5 111.7 5.9 124.4 35.2 15.2 15.5 7.9 73.3 19.9 11.8 2.6 179.2 46.8 11.2 15.7 23.0 2.5 11.5 5.4 1.0 28.7 7.9 21.6 1.5 0.6 148.1 194.4 0.4 12.3 61.8 110.0 44.7 73.4 3.2 0.0 0.3 6.7 4.6 9.7 21.2 25.7 40.5 29.7 4.3 113.1 60.3 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 RBM38 "dJ800J21.2, HSRNASEB, RNPC1, seb4B, SEB4D" ENSG00000132819 "RNA binding motif protein 38" Q9H0Z9 20 57391396-57409333 "Predicted intracellular proteins" "Cell cycle, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 136.4;skeletal muscle: 221.7" "Cell type enhanced" "Detected in many" "B-cells: 110.9;dendritic cells: 156.9;Erythroid cells: 280.4" "Cancer enhanced" "Detected in all" "ovarian cancer: 95.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 140.6;U-698: 150.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB017036 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB017036: " "unprognostic (1.03e-1)" "prognostic favorable (3.64e-7)" "unprognostic (3.71e-2)" "unprognostic (7.73e-3)" "unprognostic (4.16e-2)" "unprognostic (4.85e-2)" "unprognostic (1.53e-2)" "unprognostic (4.37e-3)" "unprognostic (3.04e-1)" "unprognostic (9.04e-3)" "unprognostic (3.90e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (2.13e-2)" "unprognostic (2.29e-1)" "prognostic favorable (1.63e-4)" "unprognostic (1.83e-1)" 11.7 10.7 6.7 26.6 9.4 136.4 12.8 13.3 10.3 18.8 15.1 96.6 8.7 38.4 0.9 16.8 28.9 5.1 72.6 5.9 6.4 16.3 16.4 21.0 43.4 8.6 11.5 27.8 10.8 1.9 12.2 5.5 8.0 27.0 4.1 0.6 19.7 11.9 221.7 9.1 39.8 8.7 6.6 65.8 23.0 38.1 9.4 26.6 9.4 32.7 12.2 42.9 13.6 7.9 20.1 20.4 9.7 25.1 0.0 1.6 56.3 6.5 1.6 13.5 3.5 84.2 20.6 140.6 54.1 1.9 13.2 18.3 8.0 8.0 2.1 29.0 34.5 118.0 7.6 52.6 6.0 57.8 54.2 1.9 3.8 5.7 1.1 1.9 9.2 52.5 100.9 24.6 1.6 87.8 42.7 58.5 36.9 10.7 25.5 82.0 23.6 114.2 10.1 9.2 40.9 26.3 15.2 50.5 24.7 8.7 28.3 79.4 17.0 4.4 42.6 6.0 27.6 60.1 86.8 150.7 1.1 40.3 4.2 0.0 0.5 2.2 3.1 1.8 1.9 3.2 2.5 2.1 1.0 3.3 3.0 2.8 0.7 3.5 1.7 1.3 4.7 2.1 6.7 9.4 13.3 10.3 5.9 6.4 8.6 11.5 8.0 6.6 9.4 7.9 13.9 3.2 5.2 10.1 110.9 9.1 28.3 7.9 13.6 1.0 15.8 21.0 42.5 8.6 6.6 1.8 0.0 1.9 156.9 41.6 9.8 6.2 4.2 54.2 5.2 11.9 62.8 280.4 2.5 5.0 5.8 8.8 12.2 21.5 8.8 31.5 10.4 6.0 9.6 0.0 1.3 56.4 12.2 8.1 18.9 4.0 4.4 27.6 1.8 2.8 5.8 12.8 54.6 4.5 4.6 5.9 35.4 6.0 52.8 18.8 2.8 16.4 22.5 1.4 6.6 20.6 7.6 2.4 13.2 9.1 8.4 2.3 81.0 13.3 34.0 18.5 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RCVRN RCV1 ENSG00000109047 Recoverin P35243 17 9896320-9905271 "Plasma proteins, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 434 "retina: 463.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1926.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "WM-115: 1.8" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA015783, CAB022363" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 17: WM-115 - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "CAB022363: , HPA015783: AB_2669298" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" "unprognostic (7.95e-3)" "unprognostic (4.82e-2)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (5.34e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-4)" "unprognostic (1.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.41e-2)" "unprognostic (9.23e-2)" 0.1 0.0 0.6 0.0 0.6 0.0 0.0 0.0 1.0 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 463.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 230.5 0.0 0.0 0.5 0.0 0.0 0.0 475.4 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 11.5 0.0 0.0 1.5 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 107.7 0.7 0.0 0.0 0.0 0.9 0.7 2.5 0.5 1.8 0.0 0.1 393.9 0.0 0.5 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1926.6 0.0 1.7 0.3 0.1 0.5 0.0 0.3 0.1 0.1 0.0 0.0 0.0 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 217.5;liver: 398.0;testis: 283.9" "Cell type enhanced" "Detected in many" "Early spermatids: 559.1;Late spermatids: 3135.0;Proximal enterocytes: 898.7" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 57.9;Hep G2: 56.2;K-562: 155.7;T-47d: 121.4" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" 8.4 86.5 11.1 1.3 12.4 1.2 17.5 10.1 18.0 5.6 7.7 3.0 217.5 3.5 14.6 14.3 4.6 7.0 3.9 12.7 8.8 22.1 398.0 1.6 1.3 9.7 10.1 7.7 28.5 2.0 9.8 1.6 9.9 20.1 1.7 94.0 17.9 6.8 2.0 9.3 199.6 0.9 8.4 1.7 4.2 283.9 12.1 0.7 6.0 0.7 1.0 9.2 7.0 10.9 7.3 9.2 2.6 34.3 5.6 2.0 39.5 1.8 0.7 1.9 1.9 57.9 22.5 3.9 12.2 1.1 2.3 7.3 9.8 0.6 1.0 1.9 4.1 21.3 1.3 56.2 4.2 1.6 6.6 4.7 4.1 0.4 1.4 3.2 1.1 4.9 155.7 5.0 0.3 29.6 1.8 4.7 12.8 21.1 19.5 4.9 1.1 10.0 10.9 2.7 0.7 17.2 9.8 14.2 6.3 1.9 121.4 5.7 3.4 2.8 5.4 8.7 1.2 16.4 5.3 0.8 11.2 9.4 8.2 0.0 1.1 0.0 5.5 1.2 2.8 0.1 1.4 1.2 1.9 0.6 2.0 2.2 0.0 4.9 4.3 3.3 1.6 1.6 11.1 12.4 10.1 18.0 12.7 8.8 9.7 10.1 9.9 8.4 12.1 10.9 1.5 3.2 3.2 2.6 2.7 6.8 7.9 6.8 10.8 30.4 47.4 20.3 1.8 91.5 10.5 5.5 33.3 69.4 2.5 7.8 7.9 34.5 559.1 4.5 7.1 4.2 6.0 10.1 1.5 69.2 12.8 4.7 2.6 3.0 10.2 132.9 5.0 267.4 9.6 23.5 1.2 51.9 4.1 6.3 4.3 3135.0 34.2 4.1 30.2 0.0 1.7 44.2 2.1 0.0 1.5 25.0 53.6 16.6 1.9 13.1 898.7 52.0 8.3 292.8 19.7 0.8 3.3 29.9 36.5 17.5 6.7 36.0 4.3 50.1 70.7 14.7 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 REM1 "GES, REM" ENSG00000088320 "RRAD and GEM like GTPase 1" O75628 20 31475288-31484895 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.1" "Cell type enhanced" "Detected in some" "Adipocytes: 7.7;Peritubular cells: 11.7;Sertoli cells: 59.2;Smooth muscle cells: 28.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 32 "WM-115: 22.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.6" HPA049821 Approved NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "HPA049821: AB_2680898" "unprognostic (6.16e-2)" "unprognostic (3.17e-3)" "unprognostic (2.62e-1)" "unprognostic (9.65e-2)" "unprognostic (6.03e-3)" "unprognostic (1.84e-2)" "unprognostic (4.39e-1)" "unprognostic (2.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.88e-2)" "unprognostic (4.77e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (7.79e-2)" "unprognostic (4.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.06e-2)" 13.9 2.2 1.2 1.7 1.1 0.0 7.5 0.9 2.1 20.1 1.3 6.5 1.3 10.5 7.2 2.0 10.0 2.2 6.2 1.0 1.0 3.2 0.8 4.6 3.0 1.0 1.1 3.9 1.1 1.1 2.7 2.1 1.1 5.5 1.0 0.0 1.6 4.9 3.3 3.2 3.7 3.2 0.9 2.5 2.4 1.4 1.3 0.7 4.8 2.4 1.5 4.8 9.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.9 2.1 1.0 1.0 1.0 1.1 1.1 0.9 1.3 1.0 7.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.4 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 7.1 2.3 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.2 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.6 5.6 0.3 3.6 1.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.8 0.0 59.2 0.6 28.1 0.0 0.2 0.1 0.9 0.0 0.1 1.5 0.0 0.0 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 REXO5 NEF-sp ENSG00000005189 "RNA exonuclease 5" Q96IC2 16 20806429-20849665 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 343.8" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 15 "basophil: 86.7" "Lineage enriched" "Detected in many" 39 "granulocytes: 86.7" "Cell line enhanced" "Detected in many" "K-562: 44.7;U-266/70: 42.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040755, HPA040868, HPA066145" Approved Approved "Nuclear membrane,Nucleoli,Endoplasmic reticulum" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" "Nucleoli, Endoplasmic reticulum" "HPA040755: AB_10965790, HPA040868: AB_10963549, HPA066145: " "unprognostic (2.39e-1)" "unprognostic (2.09e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-1)" "unprognostic (1.68e-1)" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (6.24e-2)" "unprognostic (2.26e-1)" "unprognostic (1.80e-2)" "unprognostic (8.24e-2)" "unprognostic (4.72e-2)" "unprognostic (2.42e-4)" "unprognostic (1.01e-2)" "unprognostic (8.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.93e-2)" 2.3 1.8 1.4 1.8 1.4 11.6 3.6 1.6 2.0 1.7 0.4 2.1 2.9 2.2 1.2 2.3 4.2 1.6 3.4 1.4 2.3 1.2 1.8 1.0 2.9 1.7 1.1 1.9 1.7 40.0 0.9 1.5 1.6 5.3 3.0 4.2 1.7 1.3 1.0 2.2 2.1 2.7 0.8 1.0 5.0 343.8 2.2 7.4 0.9 1.3 2.6 2.0 1.6 2.1 11.3 6.5 10.1 4.5 4.2 7.5 3.4 7.6 8.4 8.2 8.9 4.7 10.0 7.0 11.5 6.7 5.7 5.7 7.7 3.4 8.5 6.5 4.9 11.7 10.2 6.7 0.8 17.2 16.4 3.8 1.5 9.7 12.4 3.5 2.8 0.0 44.7 29.8 20.5 15.1 2.8 13.5 5.5 4.6 6.6 14.0 18.8 12.6 2.5 4.0 8.6 9.7 7.3 9.6 2.4 2.9 16.2 14.8 1.4 6.1 5.4 8.2 9.3 42.5 31.1 2.7 12.6 22.3 5.6 86.7 0.4 5.7 0.3 0.1 0.4 0.0 0.4 0.4 0.7 0.0 0.1 0.3 0.4 2.2 0.2 0.2 1.8 0.4 1.4 1.4 1.6 2.0 1.4 2.3 1.7 1.1 1.6 0.8 2.2 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.4 0.0 0.0 1.3 0.0 0.0 3.2 0.8 0.0 0.0 1.6 0.0 2.8 1.6 0.6 0.0 0.0 0.0 1.5 2.4 1.5 0.0 1.7 1.3 26.4 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.5 4.7 0.0 0.0 RFX6 "dJ955L16.1, MGC33442, RFXDC1" ENSG00000185002 "Regulatory factor X6" Q8HWS3 6 116877212-116932161 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 4.5;intestine: 2.2;pancreas: 2.3;stomach 1: 6.5" "Cell type enriched" "Detected in some" 14 "Enteroendocrine cells: 68.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HEK 293: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037696 Approved NA NA "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA037696: AB_2675616" "unprognostic (2.92e-1)" "unprognostic (4.66e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "prognostic favorable (3.59e-4)" "unprognostic (2.59e-2)" "unprognostic (1.63e-1)" "unprognostic (1.25e-1)" 0.0 4.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 6.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 68.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.3 0.0 0.0 0.4 0.0 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.5;skeletal muscle: 48.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.4;Proximal enterocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.3;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.3;monocytes: 3.5" "Cell line enhanced" "Detected in many" "HEL: 40.6;HMC-1: 19.5;K-562: 15.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 18000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 53: Intestinal epithelial cells - Unknown function" "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" 17.4 18.0 3.4 0.8 3.3 8.1 15.6 3.2 5.1 5.0 10.7 15.5 10.5 5.9 0.6 5.4 6.9 1.1 60.5 3.1 3.3 15.3 29.1 13.1 1.0 3.7 3.4 3.2 10.4 1.8 4.5 0.8 3.4 6.0 1.4 0.4 11.5 1.2 48.1 6.3 13.0 0.9 2.9 15.1 13.5 3.2 3.8 0.3 29.6 8.3 0.4 11.3 5.1 3.2 2.3 1.6 0.2 1.7 1.1 2.7 7.7 1.5 1.0 1.6 0.9 3.6 0.5 0.4 5.2 1.2 0.5 5.5 0.2 0.2 0.3 0.2 3.6 40.6 0.5 4.6 1.7 0.3 19.5 2.2 0.7 0.4 0.0 0.8 1.4 0.3 15.8 0.4 0.5 2.2 1.4 3.1 0.4 0.4 8.1 5.8 0.0 1.1 0.0 1.3 0.1 0.6 0.8 1.0 2.0 0.2 1.0 0.3 7.8 0.5 1.0 1.9 1.5 0.3 0.5 0.0 3.0 1.8 0.3 0.3 3.5 1.0 0.1 1.2 0.1 0.3 0.2 0.1 2.4 0.0 0.2 0.0 3.3 0.5 0.2 1.3 0.1 0.7 3.4 3.3 3.2 5.1 3.1 3.3 3.7 3.4 3.4 2.9 3.8 3.2 42.6 19.2 17.7 3.3 3.2 8.8 13.3 7.5 2.8 1.6 11.1 13.1 59.9 17.2 8.9 7.3 0.0 15.8 12.1 101.4 50.9 29.2 0.1 3.2 5.1 21.9 3.0 65.9 3.1 25.4 9.4 12.9 24.5 5.1 0.0 2.1 26.0 30.6 57.1 3.3 2.4 27.6 8.2 35.2 34.3 2.6 6.8 34.1 14.2 5.6 28.1 9.9 5.2 2.0 1.3 20.2 59.7 8.2 10.3 8.4 84.9 20.8 3.1 1.3 13.1 8.3 9.2 0.6 12.2 7.4 8.2 34.6 5.2 9.4 28.7 21.0 RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.2" "Cell type enhanced" "Detected in many" "Early spermatids: 13.0;Muller glia cells: 9.6;Spermatocytes: 17.3;Syncytiotrophoblasts: 13.5" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.3" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cell line enhanced" "Detected in some" "Daudi: 5.6;HEL: 21.9;T-47d: 6.1;U-266/84: 10.2" "Secreted to blood" NA NA 24400 10000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" 0.4 0.0 0.4 1.4 0.5 0.3 2.3 0.6 0.7 0.4 0.5 0.5 0.0 0.5 0.3 0.3 5.2 0.2 0.5 0.4 0.5 1.9 0.0 0.7 2.8 0.6 0.5 0.1 0.5 4.2 2.9 0.6 0.6 3.9 0.4 2.9 0.3 0.6 0.0 0.4 0.5 0.2 0.5 0.9 0.5 2.8 0.5 2.7 0.8 0.2 2.3 0.2 0.1 0.5 3.0 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.5 1.0 0.3 1.6 5.6 0.4 0.0 0.0 0.9 0.0 2.8 0.7 4.4 2.0 21.9 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.5 0.0 0.0 0.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.0 0.6 2.7 3.0 0.0 0.6 0.1 0.2 6.1 0.1 0.2 0.0 0.5 0.0 0.1 1.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 4.2 1.9 2.8 2.3 0.0 1.4 4.0 3.0 0.0 3.5 0.0 0.0 1.3 0.8 0.4 0.5 0.6 0.7 0.4 0.5 0.6 0.5 0.6 0.5 0.5 0.5 0.8 3.2 0.6 0.3 2.6 0.5 2.3 1.5 1.2 1.5 3.8 3.0 1.9 1.5 1.2 1.8 0.0 6.3 1.3 0.1 7.9 2.8 13.0 3.3 0.3 0.8 3.6 1.7 0.4 1.5 2.3 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.6 3.3 0.9 1.7 2.0 0.0 0.0 5.3 0.6 0.1 0.0 1.0 0.8 9.6 4.1 0.0 0.9 0.8 0.2 0.4 0.5 1.0 0.1 1.4 5.0 1.7 0.0 0.6 0.4 17.3 5.1 1.4 1.3 13.5 3.4 0.0 1.5 0.5 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7;choroid plexus: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 85.2" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 81.3;RPTEC TERT1: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.1 0.1 12.2 0.1 13.3 8.4 0.6 22.5 17.7 0.8 12.7 0.2 0.2 0.6 1.1 0.3 1.2 0.2 0.3 17.6 12.2 1.1 0.0 3.3 0.2 16.9 17.7 0.3 1.7 5.8 1.8 1.3 16.5 0.4 0.1 8.8 1.3 2.1 0.2 0.4 0.3 0.3 14.2 0.2 0.2 3.7 24.7 1.5 1.3 0.1 0.0 0.3 0.4 12.2 0.2 6.5 12.0 0.0 4.1 5.0 0.7 6.3 8.6 17.0 16.4 0.3 0.1 0.0 0.1 6.8 18.5 0.0 14.3 0.1 30.9 0.0 4.7 0.4 81.3 0.0 0.0 0.1 0.0 2.8 0.0 26.3 0.2 19.5 0.3 3.5 0.5 0.0 11.9 0.2 0.1 2.2 6.9 0.1 23.9 3.8 2.9 1.0 67.3 0.0 14.2 13.7 0.6 0.0 24.8 4.4 0.0 2.4 6.5 20.7 4.4 0.2 14.3 0.0 0.0 0.0 14.1 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 13.3 22.5 17.7 17.6 12.2 16.9 17.7 16.5 14.2 24.7 12.2 0.2 0.0 0.0 85.2 0.1 0.3 0.1 0.0 0.0 19.3 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.4 0.1 0.2 0.0 9.7 8.6 0.0 0.1 0.4 0.0 0.1 0.0 5.4 0.0 0.1 0.1 15.2 1.5 0.1 0.0 0.0 0.3 1.4 0.3 0.0 0.0 5.6 0.0 14.7 0.0 2.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 1.1 0.1 1.3 6.6 0.0 1.3 5.7 3.2 0.0 0.0 0.3 0.3 0.0 0.1 0.1 RPS6KA2 "HU-2, RSK3" ENSG00000071242 "Ribosomal protein S6 kinase A2" Q15349 6 166409364-166906451 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 399.6;Excitatory neurons: 204.1;Horizontal cells: 287.7;Inhibitory neurons: 552.3;Oligodendrocyte precursor cells: 244.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 26.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "eosinophil: 22.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 22.4" "Cell line enhanced" "Detected in many" "ASC diff: 214.5;ASC TERT1: 156.1;HHSteC: 158.5;HSkMC: 141.4;hTERT-HME1: 173.0;hTERT-RPE1: 316.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026243, HPA045061, HPA054237, CAB069428" Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB026243: , CAB069428: AB_1622639, HPA045061: AB_2679203, HPA054237: AB_2682425" "unprognostic (8.71e-2)" "unprognostic (3.14e-3)" "unprognostic (7.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.80e-1)" "unprognostic (2.45e-1)" "unprognostic (6.44e-3)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (8.63e-5)" "unprognostic (8.68e-2)" "unprognostic (4.11e-2)" "prognostic favorable (2.86e-5)" "unprognostic (3.12e-3)" "unprognostic (1.51e-1)" "unprognostic (1.56e-2)" "unprognostic (2.01e-1)" 34.2 9.0 40.3 8.0 41.0 10.5 27.8 35.0 35.2 18.1 8.6 16.6 6.1 26.0 7.1 20.1 18.7 18.2 61.8 37.8 42.1 13.6 6.6 45.1 7.5 48.3 41.7 29.2 19.4 49.6 27.2 17.9 42.0 14.9 10.3 28.9 14.7 14.2 24.1 16.4 16.5 22.7 35.3 26.0 21.4 7.7 47.3 5.9 36.3 30.5 7.3 24.5 14.9 49.3 9.1 0.0 17.9 26.0 214.5 156.1 0.4 19.3 37.4 10.6 14.6 0.0 5.8 1.1 6.2 68.2 8.4 8.2 9.4 41.8 9.4 4.2 2.3 0.1 40.2 0.4 158.5 0.6 7.2 141.4 29.4 56.6 173.0 316.2 58.0 19.2 0.2 0.2 43.6 1.9 0.8 2.1 4.5 9.1 10.5 3.0 9.2 27.3 11.1 10.1 9.8 68.8 6.7 17.9 24.8 4.4 0.5 14.3 21.7 37.3 3.7 103.8 5.6 5.2 8.4 2.6 24.8 1.2 36.0 0.2 0.6 22.4 0.6 0.8 0.3 0.3 0.6 0.3 0.8 0.5 0.7 0.3 0.5 4.4 2.2 4.7 0.5 0.4 40.3 41.0 35.0 35.2 37.8 42.1 48.3 41.7 42.0 35.3 47.3 49.3 60.9 22.4 46.2 399.6 2.7 4.7 5.4 4.6 3.4 37.1 7.1 5.0 60.0 15.7 11.6 36.8 8.4 0.2 8.0 1.9 11.7 15.2 14.8 20.6 4.6 58.2 5.4 0.0 204.1 24.0 0.3 16.3 16.8 20.3 2.5 10.5 45.3 11.9 7.2 287.7 552.3 5.3 2.0 6.0 6.7 69.3 5.3 8.0 19.6 144.3 3.5 10.1 1.0 244.8 97.7 26.8 1.7 4.5 2.4 9.9 0.3 7.0 9.4 17.1 13.1 10.0 14.5 3.5 2.3 1.2 3.4 0.3 2.0 9.5 1.4 6.6 RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Vesicles" "HPA018247: AB_1856475, HPA055489: AB_2682832" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (2.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.40e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (9.97e-9)" "unprognostic (2.14e-1)" "unprognostic (3.61e-2)" "unprognostic (4.98e-2)" "unprognostic (2.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.13e-2)" "unprognostic (6.38e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (3.82e-2)" 37.0 16.9 18.0 16.6 19.2 30.2 25.2 20.0 19.4 17.1 16.4 21.5 18.7 16.1 14.0 24.9 13.9 17.7 21.6 17.6 20.4 24.5 18.5 19.3 20.5 20.4 21.3 21.6 14.2 24.0 10.0 28.5 21.3 14.9 17.0 16.1 14.2 16.9 17.4 29.8 16.2 21.9 19.5 17.3 15.1 17.5 19.8 18.8 16.7 18.9 21.8 19.0 18.1 21.3 37.0 16.6 21.3 23.3 110.7 74.6 33.0 33.7 68.6 44.8 47.2 12.7 23.9 23.0 18.9 52.6 71.8 21.7 40.1 22.2 36.8 37.6 28.3 22.1 19.2 14.7 135.6 26.0 23.9 66.7 55.2 48.0 61.9 35.4 47.5 24.5 22.9 44.9 65.7 10.2 19.0 14.7 27.2 15.9 28.0 18.1 37.6 15.6 31.6 42.5 11.1 16.5 27.0 20.0 73.2 47.5 18.3 19.5 42.5 54.3 22.4 60.0 29.2 35.0 60.5 26.8 50.5 29.1 28.8 0.5 2.4 5.5 1.7 2.3 2.9 3.3 2.6 2.2 2.3 3.6 2.2 2.1 5.9 1.7 1.8 8.4 2.5 1.6 18.0 19.2 20.0 19.4 17.6 20.4 20.4 21.3 21.3 19.5 19.8 21.3 31.2 32.1 28.0 6.5 42.1 111.9 47.1 19.2 40.9 20.0 31.0 25.0 22.2 24.3 16.1 12.9 12.5 84.9 38.4 30.3 11.7 55.7 56.3 32.0 26.6 34.3 14.4 24.0 7.4 48.1 57.7 39.4 12.2 42.9 16.5 16.9 35.7 14.2 72.1 38.7 8.3 10.3 20.3 34.4 65.0 49.8 30.7 49.2 53.4 9.4 63.3 43.4 10.3 7.5 15.8 47.0 14.0 37.2 20.1 47.3 21.5 30.4 15.0 22.8 19.7 28.1 37.5 24.7 28.5 46.1 140.5 224.1 23.3 18.6 12.2 51.1 RRNAD1 "C1orf66, CGI-41, METTL25B" ENSG00000143303 "Ribosomal RNA adenine dimethylase domain containing 1" Q96FB5 1 156728442-156736960 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047426 Approved Approved Nucleoli,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoli Cytosol "HPA047426: AB_2680041" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (2.00e-1)" "unprognostic (1.86e-2)" "unprognostic (2.75e-1)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (1.98e-1)" "unprognostic (2.89e-3)" "unprognostic (2.24e-1)" "unprognostic (2.76e-1)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (1.49e-1)" "unprognostic (5.03e-3)" 17.1 21.3 16.5 14.1 20.0 11.9 21.9 18.8 18.1 22.4 20.6 21.0 27.4 22.0 26.0 21.8 28.2 17.7 14.9 15.9 17.1 18.6 28.4 17.7 19.5 20.7 18.7 26.5 27.6 25.4 20.5 14.8 18.8 25.0 17.4 17.9 27.2 22.9 30.2 29.1 24.0 14.8 18.2 20.4 23.8 24.4 18.6 14.2 29.4 22.8 17.0 22.5 20.9 22.9 14.6 28.3 20.6 20.3 54.2 24.7 31.3 10.8 32.8 18.3 13.7 15.3 65.7 24.8 31.6 17.1 25.7 60.7 28.9 25.4 7.3 49.5 24.3 15.0 27.5 11.6 34.1 22.4 39.2 38.4 47.5 18.3 34.3 21.5 15.5 21.8 36.3 54.1 9.9 35.3 11.6 26.0 23.9 63.2 8.7 18.7 13.6 58.1 21.8 15.6 26.7 38.2 19.2 38.7 24.0 31.2 51.5 47.2 15.0 11.3 13.8 17.7 14.7 62.7 67.7 31.8 12.7 24.9 13.9 4.1 1.8 2.7 3.5 1.3 3.6 1.7 3.3 2.5 3.2 2.3 2.7 3.0 4.0 4.0 2.3 1.2 5.1 1.7 16.5 20.0 18.8 18.1 15.9 17.1 20.7 18.7 18.8 18.2 18.6 22.9 9.5 6.4 15.1 11.4 15.8 10.1 21.5 13.5 22.2 11.2 20.0 19.9 7.1 31.5 13.9 3.7 12.5 24.9 8.9 16.4 9.8 12.7 60.2 12.3 6.4 9.7 9.6 14.3 4.6 13.1 17.2 11.2 18.3 10.9 5.1 8.7 12.5 19.5 10.9 8.4 6.3 16.9 14.2 11.1 4.9 14.7 11.1 9.6 8.8 4.7 10.1 20.5 5.2 5.5 15.9 9.3 12.8 9.4 14.8 21.4 36.5 12.8 13.9 13.6 13.1 9.6 9.6 20.6 23.2 18.9 11.5 32.4 8.1 8.2 16.2 18.0 RTF2 "C20orf43, CDAO5, HSPC164, RTFDC1" ENSG00000022277 "Replication termination factor 2" Q9BY42 20 56468585-56519449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 162.8;Distal tubular cells: 156.5;Proximal tubular cells: 149.9;Syncytiotrophoblasts: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053986 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA053986: AB_2682333" "unprognostic (1.65e-1)" "unprognostic (1.94e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (6.35e-4)" "unprognostic (3.54e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (8.90e-2)" "unprognostic (4.02e-3)" "unprognostic (1.16e-1)" "unprognostic (8.98e-2)" "unprognostic (3.66e-2)" "unprognostic (1.55e-2)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (4.58e-1)" "unprognostic (8.48e-3)" 73.8 72.7 101.4 65.9 113.3 128.5 65.7 117.4 106.7 66.2 88.3 79.2 60.5 70.6 48.9 64.2 64.8 49.2 85.9 97.2 106.7 68.7 63.8 58.1 70.7 113.7 109.6 71.1 59.3 63.0 67.8 55.4 115.0 58.2 54.2 61.3 51.2 62.2 181.4 69.6 60.8 65.4 111.1 67.8 59.3 57.0 108.4 79.2 60.6 111.1 76.2 73.8 57.5 123.5 132.8 93.3 91.1 91.3 111.1 97.9 85.9 198.5 148.1 280.0 158.5 192.6 125.2 110.4 232.0 161.5 139.7 144.9 92.4 153.8 190.7 52.6 72.9 138.9 97.4 150.8 127.9 201.3 186.6 88.1 156.5 126.0 106.9 119.7 121.3 118.1 109.6 114.3 139.1 253.9 171.6 173.0 68.8 185.2 175.9 116.3 247.2 149.5 119.1 86.1 95.1 103.1 208.2 355.0 199.0 66.7 165.0 191.7 131.5 242.2 156.0 133.0 165.1 94.6 116.1 156.9 190.7 134.7 135.1 309.4 205.4 562.3 125.6 192.8 106.2 115.7 106.4 122.5 223.6 134.0 119.7 110.6 580.4 197.4 200.5 189.6 152.2 254.1 101.4 113.3 117.4 106.7 97.2 106.7 113.7 109.6 115.0 111.1 108.4 123.5 87.2 51.3 61.2 0.0 20.9 0.0 0.0 0.0 0.0 0.0 54.1 56.9 0.0 0.0 34.0 66.2 0.0 162.8 50.9 0.0 156.5 104.5 0.0 47.8 51.2 38.8 0.0 0.0 0.0 96.3 109.5 37.3 0.0 47.7 90.8 57.9 0.0 0.0 110.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.8 0.0 0.0 92.0 0.0 0.0 0.0 0.0 101.9 0.0 0.0 5.3 0.0 0.0 149.9 34.2 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 182.9 26.4 89.8 0.0 0.0 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 RUBCNL "C13orf18, FLJ21562, KIAA0226L, PACER" ENSG00000102445 "Rubicon like autophagy enhancer" Q9H714 13 46334681-46438190 "Predicted intracellular proteins" "Autophagy, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.1;B-cells: 20.7;Endometrial stromal cells: 6.7;Hofbauer cells: 16.7;Macrophages: 5.2" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 17.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "memory B-cell: 161.2;naive B-cell: 155.8;neutrophil: 124.0;plasmacytoid DC: 106.2" "Group enriched" "Detected in many" 15 "B-cells: 161.2;dendritic cells: 106.2;granulocytes: 124.0" "Group enriched" "Detected in some" 4 "Daudi: 179.1;U-698: 341.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026614 Approved Approved Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA026614: AB_10602693" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" "unprognostic (1.94e-3)" "prognostic favorable (3.76e-5)" "unprognostic (1.09e-2)" "unprognostic (8.30e-4)" "unprognostic (7.83e-2)" "unprognostic (2.62e-3)" "unprognostic (1.07e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (2.28e-1)" "unprognostic (5.95e-5)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (7.47e-2)" "unprognostic (7.00e-3)" 4.2 1.3 3.7 18.0 3.8 14.8 4.0 3.5 4.1 6.6 2.5 11.9 3.0 3.7 1.2 1.0 3.7 4.0 1.0 3.4 6.8 1.1 2.2 5.2 41.2 6.2 4.8 0.6 0.7 0.3 2.0 4.2 6.1 1.5 16.2 3.9 3.0 2.6 10.1 2.0 13.2 3.6 4.9 20.3 2.2 15.7 6.3 22.9 1.9 1.4 40.6 7.5 1.3 5.9 0.5 0.1 3.6 0.2 0.1 0.2 0.3 0.0 0.2 0.2 0.1 7.5 0.2 179.1 1.8 0.0 0.9 0.2 0.1 0.0 0.1 0.7 0.3 0.2 0.2 0.1 0.0 0.2 0.2 4.7 0.0 0.6 0.9 0.0 0.0 8.2 0.3 0.4 0.0 0.1 1.9 1.4 1.5 0.0 1.4 62.6 0.1 6.1 0.0 0.1 3.4 0.1 0.2 0.3 4.4 10.8 0.2 53.0 0.1 0.2 1.6 0.3 0.4 0.9 37.3 341.2 1.1 0.3 0.2 0.5 4.5 0.1 0.1 8.9 0.1 161.2 0.3 0.1 5.1 155.8 0.1 0.1 124.0 3.5 7.1 106.2 0.2 7.5 3.7 3.8 3.5 4.1 3.4 6.8 6.2 4.8 6.1 4.9 6.3 5.9 0.2 3.2 6.1 0.0 20.7 0.0 0.0 0.0 0.0 0.0 2.9 3.9 0.0 0.0 2.5 0.0 0.0 0.3 0.3 0.0 0.0 1.4 0.0 1.3 6.7 0.4 0.0 0.0 0.0 1.2 0.4 1.1 0.0 2.5 2.5 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 RUFY4 "FLJ46536, ZFYVE31" ENSG00000188282 "RUN and FYVE domain containing 4" Q6ZNE9 2 218034960-218090581 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;lymphoid tissue: 2.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Langerhans cells: 4.0;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "Karpas-707: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037980 Uncertain NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA037980: AB_10672501" "unprognostic (1.27e-3)" "unprognostic (4.60e-3)" "unprognostic (9.39e-3)" "unprognostic (6.79e-2)" "unprognostic (5.92e-2)" "unprognostic (6.57e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-2)" "unprognostic (1.31e-3)" "unprognostic (1.50e-1)" "unprognostic (6.09e-2)" "unprognostic (1.55e-1)" "unprognostic (2.41e-14)" "unprognostic (1.36e-2)" "unprognostic (1.13e-3)" "unprognostic (3.45e-1)" "unprognostic (1.43e-5)" 0.1 0.2 0.5 0.9 0.6 0.8 0.1 0.4 1.8 0.1 0.4 0.2 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.9 0.4 0.1 0.2 0.4 1.1 0.4 0.4 0.1 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.1 0.5 0.1 0.0 0.3 0.7 0.0 0.5 2.2 0.6 0.1 0.4 1.7 0.1 0.0 0.8 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.4 1.8 0.9 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.0 0.0 0.0 2.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 4.0 0.3 0.0 0.9 0.0 1.0 2.0 0.0 0.0 13.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "dendritic cells: 157.0;NK-cells: 271.9;Plasma cells: 43.7;T-cells: 84.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.8;HDLM-2: 3.4;hTEC/SVTERT24-B: 2.2;hTERT-RPE1: 1.9;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" 1.1 2.3 1.4 4.0 2.0 4.2 0.9 0.6 1.6 2.9 0.6 1.2 0.7 4.4 1.9 0.7 1.5 2.3 0.5 2.9 1.2 1.1 1.7 3.3 10.4 0.8 2.0 1.8 1.2 0.1 4.8 0.7 0.9 0.7 2.3 1.4 0.7 0.4 0.8 0.5 1.4 1.7 0.4 9.3 1.6 3.2 1.9 6.3 0.8 0.7 4.2 1.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.3 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.3 0.0 2.2 0.1 1.9 0.2 0.4 0.1 0.0 0.2 0.0 0.1 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.5 113.8 0.4 90.0 2.5 39.8 102.1 0.6 0.3 28.8 68.9 2.3 128.4 0.6 0.6 41.7 41.4 1.4 2.0 0.6 1.6 2.9 1.2 0.8 2.0 0.9 0.4 1.9 0.4 1.1 0.0 2.3 1.3 2.3 0.4 0.0 0.0 0.6 3.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 157.0 1.6 0.0 0.2 25.4 1.0 2.1 0.8 3.6 6.6 12.1 0.0 0.0 0.7 0.0 0.5 1.3 14.8 2.9 0.4 0.0 0.0 5.7 0.3 0.0 3.4 1.4 6.7 0.6 1.8 5.4 12.2 2.3 0.0 271.9 1.5 0.6 0.0 1.5 1.9 43.7 0.0 0.1 0.6 0.7 0.4 0.0 0.3 1.4 2.3 1.6 0.2 0.4 0.0 84.3 2.0 0.5 0.1 SAMD9L "C7orf6, FLJ39885, KIAA2005" ENSG00000177409 "Sterile alpha motif domain containing 9 like" Q8IVG5 7 93130056-93148385 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "monocytes: 64.8;NK-cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 54.0;GAMG: 44.1;HDLM-2: 51.2;Karpas-707: 131.4" "Low region specificity" "Detected in all" "HPA019461, HPA019465, HPA019488" Enhanced Approved Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA019461: AB_1856555, HPA019465: AB_2183384, HPA019488: AB_1856557" "unprognostic (6.93e-3)" "unprognostic (6.12e-2)" "unprognostic (5.00e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (5.03e-2)" "unprognostic (7.10e-2)" "unprognostic (4.21e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-3)" "unprognostic (1.05e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (1.36e-1)" "unprognostic (2.07e-2)" "unprognostic (1.85e-2)" "unprognostic (1.22e-1)" 10.2 6.0 4.0 24.4 4.6 10.0 7.5 3.6 4.4 7.2 3.7 10.5 11.5 7.3 4.5 6.3 6.5 13.8 6.2 3.6 4.9 6.8 6.1 21.9 27.1 9.5 4.5 9.1 3.2 1.9 3.9 12.6 5.9 4.3 11.4 2.4 12.9 4.2 2.9 4.1 11.7 9.1 8.0 38.3 14.4 2.9 5.4 22.9 6.7 4.6 16.2 11.9 6.3 6.3 7.2 0.4 0.0 0.4 9.3 18.7 0.2 6.2 25.7 34.5 54.0 0.0 15.9 4.7 7.7 16.7 44.1 3.1 0.0 2.2 5.5 51.2 0.0 4.3 1.9 0.0 7.5 9.6 7.0 7.2 0.8 6.9 1.0 6.4 15.1 7.1 0.0 131.4 14.6 0.0 15.3 8.5 0.5 0.0 1.8 6.3 2.2 11.0 1.8 0.6 0.0 0.3 1.3 0.2 9.8 0.1 0.4 5.0 35.8 10.1 2.2 29.6 3.8 36.4 13.0 1.3 10.6 8.6 10.1 30.1 6.7 16.7 13.4 13.3 11.6 15.1 7.4 10.0 6.3 10.3 4.3 7.7 29.2 8.2 12.8 4.7 11.8 4.0 4.0 4.6 3.6 4.4 3.6 4.9 9.5 4.5 5.9 8.0 5.4 6.3 37.4 35.3 11.2 15.7 28.5 2.3 2.3 6.0 4.6 0.0 8.0 5.5 1.8 2.8 9.6 11.0 0.0 0.3 34.2 18.8 9.8 12.7 0.1 4.9 16.3 28.0 1.2 10.1 0.2 5.7 1.0 14.3 20.4 2.4 34.2 12.2 27.5 0.4 24.4 0.0 0.1 12.6 6.1 20.4 12.9 1.1 9.6 36.5 7.2 44.0 64.8 14.1 91.6 0.0 0.2 16.2 50.2 11.7 28.1 3.1 5.1 4.2 18.6 0.4 6.6 15.0 7.7 0.3 0.2 4.1 2.3 0.1 34.0 12.2 4.1 8.0 SAP25 FLJ00248 ENSG00000205307 "Sin3A associated protein 25" Q8TEE9 7 100572228-100573900 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 57.8;Spermatogonia: 86.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 30.4;NB-4: 69.1;OE19: 117.4;U-937: 27.4" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA062610 Approved "Nuclear bodies" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nuclear bodies" "HPA062610: AB_2684806" "unprognostic (1.70e-1)" "unprognostic (7.87e-2)" "unprognostic (1.09e-5)" "unprognostic (6.89e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-3)" "unprognostic (9.96e-2)" "unprognostic (4.26e-2)" "unprognostic (2.83e-1)" "unprognostic (5.04e-2)" "unprognostic (6.57e-3)" "unprognostic (1.71e-2)" "unprognostic (7.52e-6)" "unprognostic (7.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.39e-1)" "unprognostic (4.18e-3)" 8.8 4.5 18.7 17.9 21.0 28.9 4.7 19.9 26.2 11.1 18.0 5.8 6.5 4.8 0.3 4.4 9.3 5.0 6.6 18.6 20.5 15.8 7.0 14.7 28.6 22.1 19.3 23.2 6.5 1.0 12.9 5.3 20.9 11.0 1.7 13.5 8.3 2.4 3.9 6.1 20.0 2.0 18.5 47.4 5.6 25.4 21.6 17.6 15.8 1.1 8.2 5.0 7.4 24.9 4.0 1.4 2.8 1.6 0.2 0.4 6.4 3.0 0.6 1.9 0.9 3.1 4.1 2.0 1.8 0.0 0.2 4.2 0.5 0.9 0.2 3.9 2.3 3.7 3.6 1.0 0.6 4.2 30.4 0.8 1.9 1.1 0.4 1.5 0.6 8.0 4.7 7.7 0.4 9.2 7.8 69.1 4.3 117.4 1.5 16.7 0.9 3.1 0.3 1.2 1.6 5.0 0.4 3.7 4.5 3.1 5.6 15.8 3.2 2.9 6.1 2.7 2.9 13.1 3.4 1.6 0.9 27.4 3.0 0.9 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 1.1 0.0 0.2 0.3 0.0 0.0 18.7 21.0 19.9 26.2 18.6 20.5 22.1 19.3 20.9 18.5 21.6 24.9 2.2 0.0 4.1 11.1 6.7 0.0 1.3 0.0 1.2 23.7 4.6 5.3 0.0 7.2 1.3 0.0 70.9 2.6 8.7 3.1 0.0 1.9 1.4 2.1 2.0 1.7 0.0 3.4 0.9 0.7 0.7 1.3 4.1 3.2 1.3 6.0 2.5 1.1 3.1 21.9 0.9 2.3 0.0 8.5 0.0 4.6 3.4 10.7 0.0 9.4 6.5 8.0 5.2 2.5 8.2 2.0 1.9 1.2 4.1 2.8 4.9 0.3 0.0 57.8 6.6 1.5 1.8 17.2 86.6 1.5 0.0 3.6 8.2 0.9 1.5 1.8 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 270.0;lung: 508.1;salivary gland: 746.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2883.9;Breast myoepithelial cells: 4199.8;Club cells: 13674.8;Respiratory ciliated cells: 3325.6;Urothelial cells: 3139.7" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 51.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "NB-4: 2.3;T-47d: 1.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 24: NB-4 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" 1.8 1.5 1.1 0.2 1.2 0.5 122.4 0.7 1.2 270.0 11.7 0.5 0.6 1.5 1.2 74.8 29.9 2.9 0.7 1.1 5.9 1.5 7.0 508.1 0.4 1.4 1.6 2.0 18.2 0.0 12.6 0.1 1.0 37.9 0.0 0.0 746.5 2.4 0.3 4.9 1.0 0.0 1.2 9.4 50.7 3.0 3.0 0.8 3.1 0.0 0.8 14.5 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.1 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 20.3 2.4 17.2 13.3 1.8 3.3 4.5 10.1 0.0 5.9 5.0 0.0 0.0 51.8 0.2 4.3 2.6 1.1 1.2 0.7 1.2 1.1 5.9 1.4 1.6 1.0 1.2 3.0 1.5 36.4 173.1 1441.5 0.0 5.9 0.5 51.2 2883.9 0.6 0.0 1831.7 4199.8 0.4 1554.2 13674.8 0.0 0.0 0.0 30.4 0.1 0.0 20.5 0.1 1.6 0.1 40.5 0.0 10.7 0.2 1.6 0.3 15.2 3.6 1.7 35.3 1.0 68.9 1.1 0.4 0.0 0.0 0.1 1566.5 1.2 0.6 0.2 0.6 14.8 5.4 0.0 0.6 0.0 0.0 0.0 0.1 146.1 0.5 0.0 0.0 214.9 0.0 0.0 3325.6 0.0 0.0 1.6 305.2 0.3 4.4 140.8 0.4 0.0 20.2 0.1 0.2 3139.7 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.0;Distal enterocytes: 230.9;Glandular and luminal cells: 189.8;Intestinal goblet cells: 180.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 300.5;HBEC3-KT: 202.4;hTCEpi: 85.3;RPTEC TERT1: 103.7;RT4: 114.1;SK-BR-3: 96.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" 3.4 12.5 0.2 5.6 0.1 0.5 20.6 1.1 0.2 64.7 113.6 66.4 18.7 7.6 43.2 140.1 57.9 17.7 0.7 6.8 0.0 148.5 8.2 62.9 0.2 0.1 0.3 3.5 40.0 0.7 16.6 0.4 0.1 43.7 65.4 0.0 157.3 49.5 0.5 54.6 26.0 2.9 0.1 0.7 63.6 4.7 1.3 1.9 94.3 0.1 12.5 20.8 57.6 0.1 21.6 4.1 0.0 1.9 0.3 0.4 17.6 0.0 0.1 0.1 0.0 6.1 300.5 0.3 0.8 0.1 0.1 14.0 0.0 202.4 0.0 0.0 0.0 0.0 17.5 3.1 20.9 0.0 0.1 5.1 85.3 0.0 61.6 0.4 0.0 0.5 0.0 0.1 0.5 1.9 0.1 0.3 17.6 38.9 0.8 0.2 0.0 0.5 103.7 114.1 1.2 0.1 2.3 96.7 0.1 17.1 22.3 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 1.5 0.0 0.0 1.0 0.5 0.1 0.2 0.1 1.1 0.2 6.8 0.0 0.1 0.3 0.1 0.1 1.3 0.1 1.7 73.7 75.7 0.0 1.3 1.9 25.1 17.0 10.8 0.9 17.7 21.2 0.8 54.3 52.5 114.0 4.2 1.4 1.8 230.9 5.9 45.0 0.5 85.3 17.8 3.2 27.1 0.0 0.3 33.9 0.3 2.0 97.3 189.8 2.5 1.3 1.4 3.2 0.3 1.7 0.2 180.3 63.1 1.9 3.1 0.6 1.8 2.5 0.0 0.0 1.6 0.3 1.0 0.5 0.1 39.4 95.8 1.5 0.3 30.9 12.2 6.2 36.7 1.4 0.0 5.6 4.3 1.2 3.7 48.1 8.8 1.6 3.6 0.2 31.5 42.1 SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 159.0" "Cell type enhanced" "Detected in many" "Muller glia cells: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "WM-115: 326.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024517 Enhanced Approved Cytosol No No 160000 "Cluster 51: Monocytes - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "HPA024517: AB_2184811" "prognostic unfavorable (8.32e-4)" "prognostic unfavorable (8.46e-4)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.00e-5)" "unprognostic (1.87e-2)" "unprognostic (2.43e-1)" "unprognostic (1.13e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.09e-2)" "unprognostic (1.02e-1)" "prognostic favorable (1.15e-5)" "unprognostic (2.57e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (2.60e-4)" 13.9 27.9 112.4 13.1 118.9 8.1 14.3 128.2 117.9 22.2 52.2 27.5 6.5 27.4 16.2 19.0 26.0 16.5 19.8 112.5 129.0 23.7 2.6 16.4 14.3 112.5 159.0 32.4 36.7 54.5 34.0 15.8 115.5 27.9 10.4 102.5 18.0 37.2 2.4 11.1 15.8 34.3 116.1 10.8 19.3 23.0 122.5 28.9 13.5 11.0 21.6 22.0 17.8 127.1 106.3 75.0 119.9 48.6 83.1 126.9 0.5 97.0 128.8 102.5 110.0 87.1 81.8 13.0 83.7 124.7 227.3 46.7 137.7 41.2 148.9 0.6 29.0 43.8 49.7 56.6 105.9 0.3 0.5 106.5 58.1 93.5 49.6 139.4 95.9 28.0 0.5 33.3 146.6 59.5 15.5 0.1 109.4 0.2 79.6 0.3 127.7 1.1 71.7 51.5 43.7 103.1 99.9 64.1 112.5 149.7 86.3 6.9 106.7 132.2 113.3 1.7 123.7 10.8 177.0 1.1 62.4 0.5 326.5 3.7 3.4 10.3 0.9 14.1 10.7 14.0 0.2 1.0 10.9 7.6 0.7 1.4 0.5 7.1 25.4 10.8 0.0 3.5 112.4 118.9 128.2 117.9 112.5 129.0 112.5 159.0 115.5 116.1 122.5 127.1 5.9 28.9 14.1 42.7 15.4 3.1 12.6 14.0 14.2 66.9 7.6 5.2 15.8 20.0 22.3 33.1 45.9 0.4 16.2 1.1 15.6 24.1 61.1 7.3 11.9 10.9 12.1 2.5 52.0 25.1 1.9 17.2 5.6 6.7 8.2 22.9 1.8 0.3 5.4 69.0 51.4 0.7 14.2 8.8 13.9 68.1 13.7 11.1 7.2 16.9 11.5 80.8 12.3 31.2 35.6 21.2 17.3 21.1 12.5 17.4 0.1 2.8 29.2 41.1 6.6 9.6 11.9 3.1 11.0 5.1 1.7 1.0 2.8 8.5 1.2 22.3 SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 959.8;Melanocytes: 889.4" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1908.0" "Group enriched" "Detected in all" 5 "granulocytes: 1908.0;monocytes: 562.9" "Cell line enhanced" "Detected in many" "HHSteC: 787.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" 228.5 126.4 94.1 160.8 111.8 245.6 167.1 102.0 130.1 160.9 112.2 119.6 83.1 109.8 83.6 88.8 95.7 194.8 120.6 103.7 112.6 126.6 174.0 223.9 121.2 113.7 103.8 89.1 80.8 132.9 45.8 264.3 113.5 70.8 134.7 26.8 124.9 78.3 65.9 84.8 92.8 151.2 107.4 203.0 130.0 41.1 110.8 129.9 120.7 113.7 92.8 248.8 91.9 123.7 123.5 185.9 194.2 101.4 711.7 607.1 86.1 122.9 439.6 175.3 228.9 74.8 250.7 0.4 194.8 166.4 321.2 49.7 106.0 142.4 215.7 22.6 91.3 184.3 156.0 60.6 787.9 47.7 287.1 417.9 188.1 176.5 525.2 273.0 428.0 125.2 92.3 104.6 403.4 32.4 104.1 55.9 122.2 478.6 52.3 49.6 59.4 24.3 282.1 127.0 84.9 153.5 133.8 56.1 630.0 213.8 51.0 127.9 382.3 168.8 72.5 200.8 81.5 31.4 45.6 74.8 428.9 0.5 155.1 777.4 562.9 528.1 61.2 349.6 78.0 69.4 82.0 67.3 251.8 61.0 103.9 80.2 1908.0 42.6 329.1 69.9 103.0 453.2 94.1 111.8 102.0 130.1 103.7 112.6 113.7 103.8 113.5 107.4 110.8 123.7 382.7 211.5 115.9 26.8 170.3 338.7 321.2 312.5 108.1 10.8 86.7 54.6 70.6 88.6 181.3 206.0 16.7 284.3 220.2 192.9 225.0 392.9 7.8 110.9 87.0 412.7 112.3 116.6 18.5 291.6 756.8 308.1 162.1 120.5 396.9 62.9 378.3 101.9 782.5 15.2 23.7 180.3 248.2 552.1 959.8 15.9 233.9 626.0 889.4 71.2 312.4 94.3 51.5 21.6 16.3 297.9 152.9 159.9 65.1 307.4 78.4 211.2 169.8 11.1 98.6 82.7 177.4 14.8 8.4 73.3 173.2 483.0 256.2 117.0 129.2 457.6 SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" Q9BRK5 1 1216909-1232067 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA 2600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" 86.5 91.8 44.2 78.8 47.8 56.2 80.2 47.2 65.3 84.4 72.5 95.9 117.1 91.8 43.9 66.3 74.6 66.2 134.6 45.5 44.8 89.6 160.7 82.0 53.4 53.2 46.1 85.4 104.6 61.5 78.5 73.3 47.0 76.9 60.4 25.7 83.5 52.2 78.9 72.9 116.8 58.2 43.5 78.0 93.6 71.7 50.5 34.6 81.8 47.7 39.6 82.2 71.6 45.9 139.7 123.7 67.1 214.0 320.0 160.4 80.5 266.1 241.4 191.2 159.4 147.0 236.2 87.8 201.8 258.0 137.4 140.4 77.5 117.1 58.2 147.9 133.0 153.6 185.7 207.8 147.4 156.7 199.2 199.0 59.5 144.6 81.2 186.5 155.9 57.3 129.2 225.0 95.7 101.1 77.8 158.9 61.7 158.0 167.1 85.8 86.5 234.4 127.2 66.4 243.3 86.7 177.2 208.2 182.8 59.0 108.0 176.7 198.8 196.2 107.0 149.5 154.2 138.9 141.2 144.6 222.9 289.7 87.1 14.4 21.5 30.8 19.3 14.6 14.6 13.5 27.6 28.4 21.9 16.8 16.0 14.1 16.9 26.8 23.2 14.0 25.1 11.8 44.2 47.8 47.2 65.3 45.5 44.8 53.2 46.1 47.0 43.5 50.5 45.9 92.9 22.4 19.2 18.6 62.5 119.8 74.0 24.6 46.7 34.5 51.2 47.6 35.7 68.6 28.9 49.7 18.8 124.1 68.4 240.0 11.7 79.0 39.1 49.0 76.2 77.8 65.5 32.8 21.1 71.4 284.4 117.1 81.1 60.8 36.2 61.4 76.4 117.1 122.4 38.7 23.5 174.9 30.5 73.7 154.8 36.8 95.4 62.8 167.2 13.1 50.8 64.9 111.2 13.6 17.5 73.0 213.5 76.0 202.5 101.5 406.2 57.7 18.4 40.0 59.2 69.8 75.1 101.7 63.5 53.2 114.2 168.0 73.4 88.7 181.0 71.1 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 SEC14L5 "KIAA0420, PRELID4B" ENSG00000103184 "SEC14 like lipid binding 5" O43304 16 4958330-5019157 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 78.7" "Group enriched" "Detected in some" 12 "Cone photoreceptor cells: 85.5;Excitatory neurons: 67.0;Oligodendrocytes: 189.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.5;RPMI-8226: 1.6;SCLC-21H: 2.5;T-47d: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041492, HPA041825" Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA041492: AB_10794519, HPA041825: AB_10794526" "unprognostic (1.90e-3)" "unprognostic (4.08e-2)" "unprognostic (5.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (7.33e-3)" "unprognostic (8.71e-4)" "unprognostic (6.87e-2)" "unprognostic (1.56e-4)" "unprognostic (1.01e-3)" "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.61e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" 0.4 0.5 12.5 0.3 43.6 0.4 0.3 25.9 29.8 0.9 0.0 0.5 0.3 0.1 0.2 0.6 0.7 0.2 5.1 15.4 17.8 0.2 0.1 0.2 0.3 33.4 35.9 0.4 0.6 0.0 2.2 0.3 29.9 0.4 0.6 3.9 0.6 0.2 5.6 1.0 0.2 0.1 22.9 0.3 1.4 0.4 31.5 0.4 0.1 10.9 0.5 0.2 0.4 78.7 0.0 0.1 0.1 0.1 0.2 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.7 0.1 0.3 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.1 0.0 0.1 1.6 0.0 0.0 2.5 0.0 0.1 0.1 0.1 0.2 1.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 12.5 43.6 25.9 29.8 15.4 17.8 33.4 35.9 29.9 22.9 31.5 78.7 0.2 0.0 0.0 2.3 0.0 0.3 0.1 0.0 0.0 4.1 0.2 0.1 9.1 1.5 0.1 0.0 85.5 1.1 1.3 0.3 0.0 0.1 1.6 1.0 0.1 0.3 0.0 0.0 67.0 0.2 0.1 0.6 0.0 0.1 0.0 1.5 0.4 0.3 0.3 5.0 7.1 0.6 4.1 0.0 0.3 0.5 0.3 2.0 0.0 1.9 0.5 0.0 0.0 3.5 189.4 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.5 1.9 0.0 0.7 0.2 0.1 0.3 0.0 0.1 0.3 0.0 0.1 0.6 0.0 SEC16A "KIAA0310, p250, Sec16L" ENSG00000148396 "SEC16 homolog A, endoplasmic reticulum export factor" O15027 9 136440096-136483759 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005684 Supported Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 48000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "Endoplasmic reticulum" "HPA005684: AB_1079189" "unprognostic (1.24e-3)" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.30e-6)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.38e-3)" "unprognostic (4.75e-1)" "prognostic favorable (4.47e-4)" "unprognostic (5.57e-3)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (1.41e-1)" 16.8 18.2 6.4 16.6 6.7 35.3 17.1 8.0 9.4 16.6 19.3 17.3 14.9 17.9 9.0 17.9 16.4 12.4 14.5 7.0 5.2 14.3 37.9 19.4 16.9 4.4 4.9 16.2 29.2 14.0 24.3 10.8 3.5 18.7 10.5 9.2 25.8 13.1 23.5 19.7 19.1 10.7 2.4 20.7 27.2 17.6 5.2 17.4 15.3 11.9 12.3 15.9 14.5 5.0 26.5 57.7 28.5 47.2 29.6 30.3 33.6 32.1 27.9 23.4 17.8 41.9 22.1 26.4 22.1 39.2 28.8 71.3 31.8 46.2 12.7 56.2 20.7 26.9 55.1 33.7 28.6 46.2 45.8 32.8 32.5 32.7 38.1 18.9 32.2 34.5 34.1 35.6 25.0 114.3 31.2 24.9 25.1 79.0 40.4 44.3 35.2 45.0 23.8 35.0 40.0 26.6 41.6 62.2 19.8 13.8 63.6 35.9 47.0 37.6 28.1 30.8 25.2 16.9 27.7 33.4 29.2 20.6 38.3 1.7 2.8 1.2 2.5 3.1 2.7 2.3 2.6 3.0 1.6 1.4 1.6 2.8 2.0 1.5 3.4 2.6 1.9 2.4 6.4 6.7 8.0 9.4 7.0 5.2 4.4 4.9 3.5 2.4 5.2 5.0 20.0 25.6 41.7 16.6 16.4 24.9 15.3 18.4 10.8 20.2 38.7 30.6 11.5 12.8 23.6 12.9 25.0 8.1 17.5 30.1 7.9 14.2 5.1 26.9 19.5 18.2 40.7 12.0 27.4 16.4 11.8 16.0 46.9 38.2 23.5 25.4 17.9 62.2 16.5 33.7 19.2 65.5 20.3 23.4 19.5 6.0 13.1 22.3 14.2 17.8 19.5 13.0 11.3 9.5 14.7 22.8 14.7 16.6 25.1 26.3 22.3 10.1 34.7 17.1 13.1 20.5 16.6 24.4 16.1 17.2 26.9 15.1 17.8 15.8 22.8 22.1 SEL1L3 KIAA0746 ENSG00000091490 "SEL1L family member 3" Q68CR1 4 25747433-25863760 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 128.3" "Cell type enhanced" "Detected in many" "B-cells: 114.7;Oligodendrocyte precursor cells: 128.7;Plasma cells: 271.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 82.1" "Group enriched" "Detected in many" 4 "memory B-cell: 42.0;naive B-cell: 41.8;plasmacytoid DC: 38.2" "Group enriched" "Detected in many" 4 "B-cells: 42.0;dendritic cells: 38.2" "Cell line enhanced" "Detected in many" "Daudi: 287.9;OE19: 217.9;U-698: 187.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 7 "cerebellum: 100.4" "HPA040045, HPA058792" Approved Enhanced Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA040045: AB_10796116, HPA058792: AB_2683822" "unprognostic (1.01e-2)" "unprognostic (2.03e-1)" "unprognostic (3.06e-3)" "unprognostic (1.44e-2)" "unprognostic (2.43e-3)" "unprognostic (1.80e-1)" "unprognostic (1.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.33e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (5.11e-1)" "unprognostic (4.77e-2)" "unprognostic (7.21e-3)" "unprognostic (1.32e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 9.3 5.5 8.7 61.5 11.3 13.6 9.3 82.1 11.1 54.0 8.7 72.1 82.0 7.9 68.8 8.7 11.0 53.6 5.3 12.5 4.2 14.5 11.6 40.7 124.8 2.8 5.2 5.6 48.5 45.5 3.7 37.5 4.7 18.9 68.8 35.2 38.3 4.0 2.9 2.9 72.4 7.8 2.9 63.2 104.8 6.6 8.2 18.7 10.9 2.8 128.3 42.4 2.2 5.9 21.5 23.0 16.7 5.6 2.7 3.3 2.6 10.4 28.3 7.9 25.2 14.6 97.0 287.9 48.9 72.0 66.7 13.3 12.4 45.1 10.6 15.7 7.2 3.3 35.4 19.6 70.0 40.1 2.0 5.7 35.8 27.8 10.9 31.3 105.7 5.8 19.3 0.3 5.6 16.2 0.1 2.8 48.2 217.9 20.1 1.5 91.3 40.6 60.9 71.2 41.0 8.0 69.2 1.0 7.1 23.0 3.3 49.0 46.6 0.5 32.6 0.6 30.6 1.8 0.5 187.9 125.0 16.7 19.3 0.9 0.2 0.0 5.7 0.0 6.8 42.0 7.0 6.4 1.4 41.8 3.0 4.8 0.7 8.0 0.3 38.2 9.6 3.3 8.7 11.3 82.1 11.1 12.5 4.2 2.8 5.2 4.7 2.9 8.2 5.9 13.2 12.8 36.0 57.1 114.7 0.9 3.4 16.8 1.2 4.0 1.6 0.9 1.8 61.5 51.9 3.7 0.0 30.7 71.0 46.3 0.0 64.9 60.8 6.0 1.5 11.5 11.5 10.5 40.1 33.2 1.3 2.5 71.9 19.3 2.5 3.4 13.6 4.2 4.9 0.0 26.6 92.6 22.4 23.1 4.6 78.3 1.5 14.4 8.8 4.7 14.6 33.2 10.3 128.7 1.4 38.3 22.6 0.4 271.7 13.6 46.9 10.7 24.2 32.8 0.0 0.8 4.7 0.7 2.5 0.7 1.6 16.4 27.8 0.2 36.8 6.1 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 235.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.3;Distal enterocytes: 530.1;Ductal cells: 735.4;Pancreatic endocrine cells: 457.4;Paneth cells: 465.1;Proximal enterocytes: 422.0;Syncytiotrophoblasts: 446.6;Urothelial cells: 432.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 305.6;HaCaT: 349.2;HBEC3-KT: 553.0;hTCEpi: 307.8;RT4: 381.9;SK-BR-3: 311.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" 6.5 23.8 1.2 15.0 1.4 8.1 33.8 1.5 1.2 68.9 2.9 111.0 118.7 15.3 21.4 120.7 18.9 59.1 3.2 1.0 1.7 114.1 235.5 20.9 3.5 1.8 2.2 0.9 37.7 45.8 9.7 44.5 1.9 56.6 56.2 0.1 151.0 62.1 76.8 53.5 105.6 2.6 1.6 3.4 90.7 4.9 5.8 8.8 28.4 24.5 9.5 116.5 39.3 1.8 87.3 20.5 17.7 57.0 37.3 50.4 48.2 162.8 119.5 10.6 13.1 31.1 305.6 57.0 209.5 154.6 12.9 349.2 2.3 553.0 2.1 5.5 13.2 0.0 17.2 16.6 42.0 0.5 64.1 46.0 307.8 66.5 144.2 45.5 6.7 6.9 2.6 0.5 18.2 14.2 2.1 2.0 18.3 172.1 42.4 0.4 34.8 19.5 57.9 381.9 7.6 42.4 41.7 311.0 6.5 8.5 182.8 9.9 40.7 2.8 13.0 1.8 3.4 2.9 2.1 2.6 1.4 1.6 13.7 0.0 2.4 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 10.4 0.0 0.6 1.2 1.4 1.5 1.2 1.0 1.7 1.8 2.2 1.9 1.6 5.8 1.8 2.2 16.0 8.9 0.0 2.7 12.4 108.7 374.7 37.0 0.0 162.9 72.9 0.7 138.7 173.3 117.7 0.0 466.3 4.2 530.1 72.4 735.4 6.4 61.6 18.2 8.8 116.6 3.6 0.4 326.3 91.2 5.4 80.0 140.7 0.0 1.6 5.7 54.5 47.5 0.0 0.4 195.0 183.1 5.1 5.0 12.9 2.1 13.1 40.9 1.0 48.4 0.6 0.0 0.0 0.2 457.4 465.1 0.0 0.1 192.2 422.0 71.0 54.3 0.0 0.0 23.5 19.3 0.7 9.5 30.8 21.2 446.6 3.5 0.1 145.7 432.5 SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "liver: 346.9" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 259.1" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Hep G2: 21.2" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 3960000000 4700000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" 0.4 0.4 0.4 0.6 0.7 3.3 0.6 3.2 1.4 0.6 0.4 0.7 0.7 0.7 0.5 0.4 0.3 0.5 0.6 0.4 0.4 0.5 346.9 0.4 0.8 1.5 0.5 0.9 0.5 0.2 0.2 0.5 0.8 0.4 0.7 3.1 0.4 0.4 0.5 1.7 0.7 0.6 0.4 0.7 0.7 0.6 0.7 1.3 0.7 0.4 0.4 0.2 0.1 2.5 0.6 0.2 1.8 0.7 0.7 0.6 0.4 0.5 0.5 0.9 0.8 2.7 0.6 2.1 0.3 0.4 0.2 0.4 2.2 0.5 1.3 0.8 1.4 2.0 0.8 21.2 0.4 1.6 1.1 0.6 0.5 0.3 0.7 1.1 1.0 1.1 0.5 1.3 1.0 0.3 1.4 0.8 0.8 0.2 0.6 0.9 1.2 0.9 0.5 0.7 0.9 0.8 0.4 0.4 0.2 1.0 0.9 0.9 0.6 0.7 0.4 0.7 0.6 1.1 0.5 0.9 0.9 1.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 3.2 1.4 0.4 0.4 1.5 0.5 0.8 0.4 0.7 2.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 2.8 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 6.6 8.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 3.3 259.1 0.0 0.0 0.0 0.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 9176.5;pancreas: 4910.2" "Cell type enhanced" "Detected in some" "Ductal cells: 20.9;Exocrine glandular cells: 33.0;Fibroblasts: 68.6;Late spermatids: 12.2;Pancreatic endocrine cells: 18.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 7 "Hep G2: 449.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" NA NA 697000000000 94000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" 91.8 58.0 100.4 43.4 116.5 2.1 371.0 117.7 293.8 368.8 110.3 79.5 11.7 44.9 11.5 42.5 116.6 146.0 311.7 103.6 320.0 215.5 9176.5 169.9 5.0 196.3 183.1 181.5 4910.2 1.0 271.2 14.6 138.3 580.5 13.3 131.5 1505.8 54.9 177.8 55.7 91.6 83.1 141.4 31.7 290.5 66.9 176.3 2.6 72.6 38.9 6.4 207.4 70.4 173.0 0.2 0.5 0.0 0.3 0.2 0.8 0.3 0.1 0.1 0.0 0.0 1.2 4.9 0.6 4.5 0.0 3.3 0.9 0.0 4.4 0.0 2.7 0.0 1.0 0.2 449.9 56.9 1.9 0.7 52.0 63.9 0.0 2.5 5.4 0.0 0.0 0.3 0.2 0.0 17.1 0.5 0.5 0.8 1.6 0.0 0.6 2.2 0.2 3.8 0.2 0.1 0.0 1.8 2.5 65.6 0.4 2.4 0.0 0.6 0.0 8.5 0.1 19.4 1.1 2.0 2.1 0.4 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 116.5 117.7 293.8 103.6 320.0 196.3 183.1 138.3 141.4 176.3 173.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.5 1.8 0.0 5.6 2.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 20.9 3.7 0.2 0.1 0.3 0.0 0.0 0.0 33.0 0.0 68.6 9.7 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.3 0.0 0.0 1.0 0.2 0.0 0.0 0.0 18.7 0.0 0.4 0.3 0.5 0.0 0.1 1.5 0.0 0.0 1.7 0.8 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 318.8;urinary bladder: 306.7" "Cell type enriched" "Detected in many" 4 "Fibroblasts: 806.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "AF22: 229.1;ASC diff: 85.2;HSkMC: 140.2;NTERA-2: 318.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" 188.2 16.0 4.9 84.6 4.0 0.3 154.9 3.6 6.3 23.2 11.2 72.2 18.4 12.0 22.2 212.7 62.1 318.8 6.2 12.3 13.8 4.5 0.3 62.5 11.8 4.5 3.7 8.3 45.1 7.0 72.5 0.4 4.6 56.5 44.3 2.3 83.4 70.5 6.5 80.5 57.3 89.5 3.8 0.7 34.4 1.5 2.2 9.6 92.3 38.7 3.6 306.7 63.0 12.3 0.0 0.0 229.1 0.2 85.2 15.1 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 140.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 318.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.1 0.1 0.0 8.1 0.2 0.0 0.0 0.4 0.1 0.0 12.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.0 3.6 6.3 12.3 13.8 4.5 3.7 4.6 3.8 2.2 12.3 15.5 3.2 0.6 9.4 0.5 115.5 0.8 0.0 5.7 0.0 3.7 7.9 0.3 0.0 1.9 0.0 0.0 0.1 2.0 0.0 0.0 0.2 0.0 0.1 0.1 11.8 0.0 0.0 0.7 0.0 0.2 806.1 38.7 0.3 1.3 0.0 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.0 175.0 0.5 4.1 5.0 119.2 0.0 0.6 0.0 0.0 0.5 0.1 0.1 0.0 7.2 4.1 0.7 0.0 0.1 2.9 0.0 0.0 6.7 59.4 0.0 0.1 6.9 106.0 0.1 8.6 0.0 0.0 0.9 SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 619.9;endometrium 1: 467.1;fallopian tube: 214.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 472.1;Fibroblasts: 196.4;Granulosa cells: 102.8;Peritubular cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.0;HSkMC: 3.9;U-937: 3.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 53.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" NA NA 2500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" 29.1 15.6 2.3 1.4 3.0 0.8 60.0 2.7 4.5 619.9 2.1 4.4 1.2 467.1 18.7 2.3 214.0 17.3 22.4 2.5 4.6 4.3 0.6 14.7 7.3 4.0 4.8 79.2 5.0 2.8 20.5 0.2 3.2 16.1 2.6 2.3 6.5 43.9 4.1 1.5 1.4 87.9 4.0 13.9 2.3 16.8 2.7 1.6 14.9 7.0 2.0 37.4 61.0 3.9 0.0 1.8 2.1 0.0 10.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 2.2 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 1.5 0.1 0.3 0.0 3.9 0.5 0.4 0.0 0.7 0.1 0.1 0.0 0.2 0.1 0.3 0.0 1.2 0.1 0.0 0.0 0.1 1.3 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.4 0.0 0.0 0.7 0.0 0.8 1.2 0.1 0.4 0.1 0.1 0.2 3.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 2.7 4.5 2.5 4.6 4.0 4.8 3.2 4.0 2.7 3.9 5.5 0.0 1.8 0.3 0.7 1.0 1.5 0.1 0.6 0.0 0.5 2.3 1.0 0.0 0.7 0.0 0.0 0.2 0.4 0.0 0.0 0.0 1.0 22.5 472.1 4.6 0.0 0.0 0.0 0.5 0.3 196.4 0.0 14.1 0.0 102.8 3.3 0.1 0.2 0.0 0.5 0.0 0.0 0.0 4.4 2.8 41.7 7.1 0.0 2.8 0.0 2.7 0.0 17.6 0.2 0.1 0.0 188.4 0.0 2.4 0.0 1.8 0.0 0.3 0.0 30.5 25.3 0.2 0.4 0.1 1.6 0.3 9.2 1.2 0.1 0.5 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 SGSM2 "KIAA0397, RUTBC1" ENSG00000141258 "Small G protein signaling modulator 2" O43147 17 2337498-2381058 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021641, HPA024553" Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 14: REH - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA021641: AB_2188702, HPA024553: AB_1856512" "unprognostic (1.06e-1)" "unprognostic (4.76e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-2)" "unprognostic (4.88e-2)" "prognostic favorable (3.11e-4)" "unprognostic (1.49e-1)" "unprognostic (7.84e-2)" "unprognostic (7.63e-2)" "unprognostic (1.90e-1)" "prognostic favorable (9.00e-6)" "unprognostic (2.78e-2)" "unprognostic (8.27e-2)" "unprognostic (1.80e-1)" "unprognostic (2.58e-1)" "unprognostic (1.56e-1)" "unprognostic (3.07e-2)" 22.2 30.2 84.3 20.2 83.0 28.4 31.0 52.5 102.7 32.1 53.8 37.0 15.5 26.3 51.7 36.0 27.4 21.2 27.1 83.0 81.3 36.5 19.3 28.2 24.3 64.0 67.5 28.9 27.9 27.4 80.7 15.8 62.6 53.7 10.1 15.7 41.9 21.6 21.6 33.3 32.6 17.9 58.4 37.6 33.6 30.0 76.9 17.5 41.4 13.9 14.1 31.8 28.7 68.4 20.7 31.1 27.9 39.0 15.5 18.6 41.4 17.4 20.4 23.6 23.9 31.2 38.6 9.9 18.5 25.3 8.7 28.4 17.2 20.6 8.2 14.5 35.3 17.2 55.6 33.8 13.3 10.4 25.0 20.1 13.4 24.1 13.7 34.1 24.9 26.4 10.5 14.4 14.3 43.5 22.4 14.0 13.7 14.7 13.5 48.5 14.2 8.0 30.5 42.5 13.5 31.9 21.7 16.2 13.4 17.1 41.9 12.3 29.3 18.9 21.5 28.1 23.4 11.8 1.9 9.5 16.4 13.6 17.0 7.0 0.3 1.3 0.9 0.1 0.8 0.1 0.3 0.5 0.4 0.3 1.1 0.6 0.1 0.9 0.0 0.5 0.6 0.4 84.3 83.0 52.5 102.7 83.0 81.3 64.0 67.5 62.6 58.4 76.9 68.4 9.4 6.4 24.7 52.9 5.4 6.8 8.3 13.8 5.7 59.6 31.9 24.0 15.6 11.5 23.5 12.9 135.5 13.8 9.3 7.1 0.0 6.7 18.2 9.9 11.0 11.8 13.8 5.7 39.7 4.5 8.8 10.0 14.3 14.7 20.3 18.1 14.3 8.3 7.8 30.3 38.2 9.9 16.2 7.6 9.9 38.1 8.1 9.2 5.4 16.9 6.3 11.9 7.2 22.6 10.3 6.4 4.5 12.0 4.6 15.0 7.0 4.0 16.5 51.2 19.7 9.6 11.0 4.1 6.7 11.9 7.7 14.1 11.6 15.2 8.2 13.5 SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.7" "Cell type enhanced" "Detected in many" "Kupffer cells: 113.6;Langerhans cells: 130.9;Macrophages: 84.1;monocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 122.2;hTEC/SVTERT24-B: 140.7;U-87 MG: 211.6;WM-115: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" 22.2 10.9 10.2 21.9 6.8 60.7 13.3 3.5 9.3 8.6 8.5 11.4 8.1 8.5 3.3 7.7 8.1 18.6 23.4 5.8 6.5 14.3 17.4 20.5 21.0 12.0 7.3 5.5 10.2 5.8 8.0 24.4 10.0 7.3 13.5 3.7 5.3 5.9 9.6 4.1 12.5 13.6 10.1 37.1 7.1 9.5 12.1 10.5 11.1 9.5 15.8 15.7 6.0 14.7 9.2 5.5 7.0 7.3 23.9 35.5 4.8 29.2 79.5 21.9 23.3 8.4 5.2 15.6 20.3 44.6 73.6 1.7 5.5 16.9 35.2 13.3 2.7 53.2 2.6 6.2 23.3 23.5 122.2 21.2 3.8 140.7 12.7 48.4 119.1 12.8 38.9 6.1 80.2 3.2 9.7 46.7 11.0 2.4 21.0 9.5 15.9 10.2 10.5 3.7 4.6 4.9 5.4 0.6 42.2 6.2 3.5 33.4 93.0 20.0 11.3 17.4 48.1 13.9 15.8 17.6 211.6 16.6 165.3 0.9 3.5 1.2 1.2 8.4 1.0 1.5 1.1 1.3 4.8 0.5 0.7 1.0 3.0 1.8 6.6 4.9 0.4 1.8 10.2 6.8 3.5 9.3 5.8 6.5 12.0 7.3 10.0 10.1 12.1 14.7 26.8 3.2 22.0 2.6 26.2 6.8 1.5 4.2 1.2 4.6 4.3 3.8 17.5 4.3 4.3 1.8 2.1 0.4 40.6 15.0 1.9 3.6 13.1 1.0 2.2 39.2 3.5 11.2 11.0 9.0 1.4 8.1 0.5 1.2 38.6 0.8 46.1 11.1 40.4 3.3 7.3 3.0 6.1 113.6 130.9 5.3 2.8 84.1 16.0 38.4 67.1 1.1 18.6 11.1 9.0 7.2 5.9 4.1 4.9 3.0 0.8 1.5 3.5 3.4 0.0 4.0 12.7 12.5 4.5 0.7 4.1 1.0 12.1 4.4 3.2 1.2 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SH3PXD2B "FLJ20831, KIAA1295" ENSG00000174705 "SH3 and PX domains 2B" A1X283 5 172325000-172454525 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 91.1;Leydig cells: 39.7;Oligodendrocytes: 63.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 95.2;ASC TERT1: 79.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036471 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli fibrillar center" "HPA036471: AB_10670799" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "unprognostic (4.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (5.38e-3)" "unprognostic (3.11e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.87e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-2)" "prognostic unfavorable (8.45e-4)" 22.6 25.4 9.2 11.2 12.8 0.1 19.0 12.9 11.5 36.4 9.6 14.0 2.3 32.6 5.4 10.5 17.9 18.9 7.4 9.8 10.7 2.4 2.9 17.6 3.5 14.5 12.8 18.4 9.8 6.6 5.0 8.9 16.0 12.8 5.6 3.6 18.3 13.9 3.5 19.8 11.5 23.2 10.1 6.5 13.1 6.3 13.7 4.2 8.0 3.4 3.4 18.3 18.1 15.4 1.0 14.3 52.3 34.6 95.2 79.9 44.3 8.6 29.7 5.4 10.7 4.0 1.3 0.1 11.5 33.4 16.7 8.1 18.7 9.8 5.3 0.8 3.5 0.1 13.3 2.9 30.6 0.0 36.5 51.5 15.1 22.4 6.4 5.2 37.9 3.8 0.1 0.2 24.1 3.1 0.1 4.6 20.1 8.1 3.3 17.3 8.5 5.1 5.7 1.5 4.6 29.2 6.0 3.8 10.7 16.5 1.4 2.1 40.9 33.4 13.2 20.7 3.8 0.0 0.0 0.2 22.6 2.2 27.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.8 12.9 11.5 9.8 10.7 14.5 12.8 16.0 10.1 13.7 15.4 11.3 0.0 1.1 91.1 0.4 10.1 3.2 13.9 8.6 0.6 6.2 6.5 1.8 5.7 12.0 0.0 0.0 4.5 0.2 1.3 0.0 9.9 0.9 5.5 30.8 6.4 2.4 0.0 5.0 16.0 31.0 29.8 6.1 13.4 0.0 5.8 3.3 1.8 3.1 1.7 11.2 2.1 18.3 28.4 9.4 2.0 39.7 13.6 14.2 13.1 1.3 6.3 0.0 25.1 63.0 21.8 1.0 27.1 0.0 6.9 0.2 1.9 3.8 0.3 13.1 6.0 10.5 0.8 4.2 4.7 8.1 2.2 0.5 22.3 2.7 5.7 SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.6;retina: 3.9" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 270.4" "Cancer enhanced" "Detected in some" "melanoma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.6;HBEC3-KT: 2.2;RT4: 3.6;SK-MEL-30: 5.2;WM-115: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA037683: AB_2675608, HPA037684: AB_10672603" "unprognostic (6.30e-2)" "unprognostic (4.07e-2)" "unprognostic (4.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.70e-1)" "unprognostic (1.92e-2)" "unprognostic (2.49e-1)" "unprognostic (2.17e-4)" "unprognostic (2.18e-2)" "unprognostic (4.53e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (6.62e-2)" "unprognostic (1.40e-1)" 0.1 0.0 4.7 0.0 8.0 0.1 0.1 5.1 5.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.3 3.6 5.1 0.0 0.0 0.0 0.0 7.1 6.9 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.0 3.9 0.1 0.1 0.2 0.1 0.0 0.0 5.8 0.0 0.0 1.5 7.1 0.0 0.0 0.1 0.0 0.1 0.0 12.6 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.3 0.1 2.6 1.5 0.0 1.8 0.1 0.6 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 1.1 1.6 0.0 1.3 0.0 0.7 3.6 0.0 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.2 0.1 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 8.0 5.1 5.0 3.6 5.1 7.1 6.9 7.3 5.8 7.1 12.6 1.9 3.2 3.7 0.3 0.1 0.9 0.8 1.0 0.0 1.4 0.7 0.4 1.7 1.5 3.8 0.0 4.2 0.8 0.0 0.6 0.0 0.6 6.4 0.3 0.1 2.8 0.0 0.0 0.4 0.2 0.4 0.5 0.0 0.5 2.5 0.1 1.4 0.3 0.4 0.0 0.4 0.0 2.0 1.8 0.7 2.3 0.3 2.2 0.0 4.7 0.1 2.3 0.0 0.0 270.4 1.6 0.0 0.0 0.1 1.2 0.0 0.1 4.1 25.4 0.0 0.3 0.4 2.3 0.9 1.0 0.9 11.9 0.3 0.1 0.2 8.8 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHISA4 "C1orf40, hShisa4, TMEM58" ENSG00000198892 "Shisa family member 4" Q96DD7 1 201888680-201892587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;skeletal muscle: 219.7" "Cell type enhanced" "Detected in many" "Muller glia cells: 37.5" "Cancer enhanced" "Detected in all" "glioma: 49.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 24.6;intermediate monocyte: 8.1;neutrophil: 9.1;non-classical monocyte: 10.2" "Group enriched" "Detected in many" 10 "granulocytes: 24.6;monocytes: 10.2" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 23.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061273, HPA067885" Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" "HPA061273: AB_2684460, HPA067885: " "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (1.48e-3)" "unprognostic (2.12e-3)" "unprognostic (6.59e-2)" "unprognostic (8.29e-3)" "unprognostic (7.06e-2)" "unprognostic (5.00e-2)" "unprognostic (2.32e-1)" "unprognostic (1.44e-1)" "unprognostic (8.29e-2)" "unprognostic (2.32e-2)" "unprognostic (1.63e-3)" "unprognostic (1.20e-1)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-1)" 6.7 26.9 64.6 2.0 71.6 0.5 5.9 61.5 59.4 9.2 27.3 7.7 0.4 10.9 3.5 2.7 6.9 3.6 48.6 55.5 53.3 6.4 3.2 5.2 0.8 63.9 64.9 10.7 5.1 3.9 9.2 2.3 58.0 8.5 0.9 4.7 15.7 4.0 219.7 3.6 3.5 3.7 59.1 2.8 6.7 5.7 68.4 0.3 11.4 58.3 0.6 8.6 6.4 57.1 1.3 10.5 1.6 7.8 12.7 7.7 1.3 9.1 19.3 5.2 6.5 2.0 4.1 0.0 10.6 12.6 17.2 3.4 0.1 1.4 3.0 1.3 0.6 0.1 2.8 1.3 8.2 0.1 6.7 7.6 4.3 6.5 3.0 23.2 8.0 0.1 0.2 0.7 8.1 1.3 0.0 0.0 0.8 0.9 11.3 0.4 0.0 2.1 5.0 4.1 0.5 6.6 3.3 1.6 10.9 7.6 4.4 1.0 7.5 6.3 5.5 3.9 4.4 2.4 2.9 0.1 9.2 0.0 11.2 0.0 1.7 24.6 1.7 8.1 0.8 0.0 0.3 0.4 0.9 0.0 0.0 0.3 9.1 0.0 10.2 0.0 0.0 0.7 64.6 71.6 61.5 59.4 55.5 53.3 63.9 64.9 58.0 59.1 68.4 57.1 12.8 0.0 1.7 14.4 0.3 14.1 4.5 7.4 6.8 11.7 8.2 14.4 20.9 8.6 3.7 11.0 4.2 2.0 0.9 0.1 33.2 24.9 0.7 2.4 10.0 11.1 1.8 0.0 8.4 15.4 27.2 19.2 3.6 2.7 1.3 10.4 12.5 12.1 3.2 5.0 6.5 0.1 6.1 6.9 25.1 2.3 15.8 3.7 23.2 1.0 4.6 37.5 0.0 17.6 19.2 9.5 0.0 29.3 0.2 7.4 0.0 6.3 1.3 3.8 19.7 9.2 18.0 1.4 0.8 0.9 6.8 2.7 1.5 2.3 0.1 2.1 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 63.6;Syncytiotrophoblasts: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.6" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" 23.3 22.9 6.1 13.1 6.2 34.0 21.0 6.8 7.9 27.1 5.8 22.5 13.9 29.6 18.4 31.2 22.8 21.3 23.2 5.9 6.1 20.6 10.3 22.7 15.1 7.4 6.8 40.8 22.8 9.6 18.8 21.1 7.4 22.9 8.3 2.0 17.4 15.7 18.3 42.9 18.7 13.5 6.9 19.3 18.9 8.9 8.1 9.8 20.6 9.4 11.2 31.8 26.0 7.7 66.4 27.0 7.3 38.3 25.2 27.6 48.9 49.2 29.2 32.5 32.3 25.0 31.8 51.0 91.1 46.8 41.3 55.9 24.4 24.7 8.6 32.7 11.8 15.9 36.0 20.3 47.0 19.0 24.9 34.8 28.1 29.9 15.8 28.5 22.6 8.7 17.6 48.6 21.6 90.0 10.2 17.0 5.9 32.4 54.9 16.8 19.9 38.8 24.7 24.2 6.8 12.0 29.8 55.4 13.0 8.5 17.9 15.0 29.5 38.0 23.9 89.6 63.2 34.3 35.6 52.8 40.9 39.6 20.2 218.6 4.5 21.1 12.9 6.5 9.6 5.3 8.5 9.2 3.9 5.2 6.0 5.9 6.1 8.8 5.6 9.5 6.4 6.3 6.1 6.2 6.8 7.9 5.9 6.1 7.4 6.8 7.4 6.9 8.1 7.7 13.3 3.2 7.0 2.3 21.1 22.6 27.1 15.2 50.7 2.8 13.7 11.8 4.0 15.7 7.3 18.4 6.2 49.5 17.4 22.1 7.9 17.8 3.6 13.0 14.8 15.8 10.2 11.1 1.6 19.4 63.6 21.2 13.7 21.0 12.7 15.8 16.8 2.3 19.4 3.3 1.4 15.5 4.1 8.4 19.6 1.2 27.1 22.7 3.6 1.0 13.2 3.0 23.7 1.5 1.6 20.9 16.0 13.2 19.8 14.1 17.2 10.4 6.9 1.9 6.6 12.1 14.3 1.9 2.9 45.5 27.8 103.0 24.5 5.4 11.7 23.5 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 18.2;Gastric mucus-secreting cells: 29.0;Hepatocytes: 48.8;Hofbauer cells: 18.0;Intestinal goblet cells: 19.7;Plasma cells: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 35.7;CACO-2: 32.9;Hep G2: 69.5;NB-4: 39.0;RPMI-8226: 36.1;U-937: 43.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047470 Approved Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 1.3 1.0 0.3 5.8 0.5 11.4 1.3 0.7 0.7 1.9 0.7 3.7 5.5 1.5 0.2 0.8 1.9 1.3 1.3 0.6 0.8 0.9 43.0 3.5 5.2 1.2 0.9 1.7 1.4 0.0 2.2 1.7 1.3 1.3 3.1 0.0 4.0 0.6 1.0 0.7 4.2 1.4 0.9 11.1 9.5 0.4 1.2 0.7 1.2 0.1 4.2 2.7 1.7 2.0 0.0 0.0 0.0 0.2 0.3 3.1 0.1 35.7 10.0 11.4 18.0 32.9 0.0 25.9 0.0 28.3 0.0 0.0 5.0 0.0 2.8 0.0 0.0 11.5 0.9 69.5 7.7 20.9 0.0 2.5 0.0 13.6 0.0 0.0 7.6 0.1 0.1 14.6 0.0 0.0 0.9 39.0 0.0 12.9 0.2 26.9 0.0 36.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.4 2.6 0.0 0.0 1.2 0.0 5.0 0.3 14.2 0.0 43.8 0.0 0.0 0.9 0.0 0.7 1.7 0.5 2.2 0.0 0.4 2.6 1.7 0.0 0.3 0.0 4.9 0.3 0.0 0.1 0.7 0.3 0.5 0.7 0.7 0.6 0.8 1.2 0.9 1.3 0.9 1.2 2.0 1.1 0.0 1.1 0.0 18.2 0.9 0.2 0.3 0.0 0.4 1.0 1.0 1.3 12.8 1.0 0.0 0.0 0.3 5.5 6.4 0.0 0.3 0.7 2.6 7.3 1.4 3.0 1.7 0.7 0.4 0.9 4.0 29.0 2.5 5.1 2.4 1.4 48.8 18.0 0.0 0.4 19.7 0.0 5.1 12.4 0.6 1.2 7.2 5.4 2.8 1.3 0.1 4.1 1.0 0.1 1.7 3.1 0.7 38.6 0.6 0.2 0.4 0.8 0.1 0.0 1.6 4.2 0.4 1.0 0.0 1.1 0.8 3.6 3.8 9.3 0.6 SLC1A2 "EAAT2, GLT-1" ENSG00000110436 "Solute carrier family 1 member 2" P43004 11 35251205-35420063 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 782.3;choroid plexus: 202.7" "Cell type enriched" "Detected in many" 7 "Astrocytes: 4607.2" "Cancer enriched" "Detected in some" 5 "glioma: 28.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;BJ hTERT+: 2.4;fHDF/TERT166: 1.7;Hep G2: 2.9;NTERA-2: 3.1;SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002574, HPA009172, HPA067499" Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB002574: AB_564087, HPA009172: AB_1849764, HPA067499: " "unprognostic (8.00e-2)" "unprognostic (5.71e-3)" "unprognostic (1.39e-1)" "unprognostic (2.77e-2)" "unprognostic (1.33e-1)" "unprognostic (5.65e-3)" "unprognostic (1.39e-2)" "unprognostic (9.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.65e-2)" "unprognostic (1.79e-3)" "unprognostic (2.35e-1)" "unprognostic (8.33e-4)" "unprognostic (6.34e-2)" "unprognostic (8.06e-2)" "unprognostic (5.24e-2)" "unprognostic (3.49e-2)" 0.6 4.6 546.9 0.6 731.2 0.4 3.8 388.1 782.3 1.2 202.7 0.2 0.5 1.0 0.3 0.2 0.3 0.2 0.9 631.1 432.5 0.2 34.9 0.6 1.9 450.6 533.6 0.1 9.5 0.1 2.6 1.1 384.2 0.3 0.1 60.1 4.6 0.1 0.3 1.3 0.2 0.3 409.7 0.5 2.1 1.7 498.7 0.2 0.3 0.5 1.6 0.3 0.6 453.4 0.0 0.1 0.5 0.0 0.2 2.1 0.0 0.5 2.4 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.3 2.9 0.1 0.3 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.2 0.0 1.1 0.0 0.1 0.5 0.0 0.3 0.1 0.1 0.2 0.0 0.3 0.0 0.0 0.5 0.0 0.1 1.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.2 0.1 0.5 0.2 0.1 0.1 0.1 0.1 546.9 731.2 388.1 782.3 631.1 432.5 450.6 533.6 384.2 409.7 498.7 453.4 0.4 3.2 4.8 4607.2 0.4 2.9 0.0 0.0 0.0 109.9 8.1 2.4 3.1 0.0 0.0 0.0 148.0 25.6 0.3 0.1 0.0 0.1 96.6 1.8 11.7 1.6 0.0 0.0 83.7 3.4 1.0 3.1 1.1 1.5 0.0 0.7 0.0 6.7 3.3 6.7 81.5 0.0 0.0 0.0 3.0 97.9 0.0 0.6 1.8 194.9 31.6 10.1 0.0 634.9 12.3 0.4 0.0 0.0 0.1 0.3 0.0 0.1 0.8 161.2 0.0 0.3 1.8 0.5 1.3 0.0 1.1 269.4 0.2 0.0 0.0 0.1 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 SLC1A7 EAAT5 ENSG00000162383 "Solute carrier family 1 member 7" O00341 1 53087179-53142638 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 40.2" "Group enriched" "Detected in some" 6 "Bipolar cells: 207.7;Cone photoreceptor cells: 70.9;Rod photoreceptor cells: 72.3" "Cancer enhanced" "Detected in many" "lung cancer: 3.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.2" "Lineage enriched" "Detected in single" 22 "T-cells: 2.2" "Cell line enriched" "Detected in some" 8 "HHSteC: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049124 Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "HPA049124: AB_2680643" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (9.48e-4)" "unprognostic (2.31e-1)" "unprognostic (8.73e-2)" "unprognostic (1.52e-2)" "unprognostic (6.26e-3)" "unprognostic (4.35e-1)" "unprognostic (1.45e-2)" "unprognostic (1.59e-1)" "unprognostic (7.65e-2)" "unprognostic (1.19e-3)" "unprognostic (2.58e-3)" "unprognostic (5.43e-2)" "unprognostic (8.12e-2)" "unprognostic (4.70e-3)" 1.6 0.2 1.5 0.2 1.0 0.0 1.1 1.0 1.5 1.4 0.8 1.0 2.3 1.3 0.0 1.2 1.8 5.2 1.6 1.2 1.1 0.4 1.0 0.6 0.1 1.6 1.9 2.4 0.2 0.4 0.1 0.2 1.8 0.8 0.0 40.2 0.5 0.0 1.3 0.8 3.1 0.0 1.5 0.0 0.8 0.5 2.3 0.0 0.6 3.0 0.0 1.0 1.1 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.3 1.5 1.0 1.0 1.5 1.2 1.1 1.6 1.9 1.8 1.5 2.3 1.2 1.9 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.6 0.0 0.0 0.0 70.9 0.1 3.0 2.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.2 5.9 4.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.2 0.5 0.0 7.5 0.0 8.5 16.5 0.0 0.1 0.0 4.0 1.2 0.7 0.0 17.7 0.7 0.0 72.3 0.0 1.1 0.5 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.3 0.0 SLC22A12 "OAT4L, RST, URAT1" ENSG00000197891 "Solute carrier family 22 member 12" Q96S37 11 64590641-64602353 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "kidney: 109.4" "Cell type enriched" "Detected in some" 17 "Proximal tubular cells: 173.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA024575 Enhanced NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024575: AB_1858650" "unprognostic (5.88e-2)" "unprognostic (2.33e-1)" "prognostic favorable (2.63e-4)" "unprognostic (6.19e-2)" "unprognostic (3.91e-2)" 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 109.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 SLC25A38 FLJ20551 ENSG00000144659 "Solute carrier family 25 member 38" Q96DW6 3 39383370-39397351 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041027 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "HPA041027: AB_10794403" "unprognostic (3.82e-2)" "unprognostic (3.27e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-2)" "unprognostic (3.94e-2)" "unprognostic (1.94e-1)" "unprognostic (1.26e-2)" "unprognostic (5.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "prognostic favorable (7.29e-4)" 19.1 35.4 22.2 18.8 23.3 70.0 21.0 25.9 26.8 23.8 33.6 28.1 25.3 27.3 27.6 14.5 27.3 19.4 20.7 22.9 26.3 28.7 58.0 21.0 36.2 24.2 24.1 44.1 45.6 38.7 30.7 15.4 25.3 29.2 36.9 23.0 22.5 23.9 48.2 16.7 25.2 20.3 22.6 27.2 33.8 18.7 26.0 33.6 52.0 35.7 35.4 27.8 19.1 23.3 24.3 38.3 24.3 41.2 56.4 46.4 30.8 33.6 46.1 48.3 43.7 26.3 5.6 67.8 19.6 31.6 40.7 18.4 55.2 40.1 36.0 43.6 45.0 52.0 33.5 40.2 75.6 37.7 33.9 58.8 46.1 46.2 93.2 44.6 31.5 52.8 47.7 40.6 36.4 35.2 44.7 67.0 66.2 35.9 44.3 16.2 26.4 47.7 37.5 45.4 24.3 31.1 11.9 65.9 34.0 44.5 33.5 35.0 26.9 38.3 26.4 56.2 48.9 54.7 93.1 41.9 29.3 48.3 24.7 30.7 9.6 18.1 38.8 5.7 44.7 50.8 39.1 43.3 14.9 37.8 41.7 40.5 1.0 57.0 8.4 18.5 55.3 29.2 22.2 23.3 25.9 26.8 22.9 26.3 24.2 24.1 25.3 22.6 26.0 23.3 10.4 22.4 27.4 8.5 35.6 11.5 13.0 12.5 28.5 13.2 26.1 22.6 16.8 22.8 9.6 27.6 6.2 35.2 33.1 21.9 21.5 15.7 6.5 26.6 16.3 11.1 12.6 73.7 8.9 16.9 32.6 13.7 16.8 38.5 22.2 24.0 9.7 27.0 15.2 5.0 10.1 25.6 12.2 7.0 13.7 12.9 15.5 9.8 12.4 1.9 11.2 18.9 29.9 7.1 6.2 13.4 22.2 13.5 23.3 17.7 23.1 31.3 12.3 12.6 6.6 15.2 14.9 11.0 7.8 19.4 10.2 19.4 36.6 32.8 26.7 8.4 SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1120.4" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 2328.4" "Cancer enriched" "Detected in many" 14 "colorectal cancer: 52.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036055 Approved NA NA "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036055: AB_10602401" "unprognostic (1.26e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.69e-1)" "unprognostic (4.02e-1)" "unprognostic (4.09e-2)" "unprognostic (3.05e-3)" "unprognostic (6.31e-2)" "unprognostic (1.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (8.85e-2)" "unprognostic (8.01e-2)" "unprognostic (5.52e-2)" "unprognostic (2.54e-2)" "unprognostic (3.58e-3)" 1.1 0.0 0.0 19.7 0.0 0.0 59.5 0.2 0.1 0.3 0.0 1120.4 576.9 0.9 15.3 0.5 0.8 17.8 0.0 0.0 0.0 0.8 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.1 878.8 0.1 0.0 129.9 0.0 0.1 118.5 15.0 0.0 0.0 1.3 0.9 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 165.9 4.2 0.0 0.3 0.0 0.0 0.0 51.4 41.7 0.3 34.3 0.0 0.0 0.0 0.0 0.0 2328.4 0.0 0.0 6.4 1.8 0.1 0.3 14.3 0.0 110.2 0.0 0.0 0.1 0.0 0.2 26.7 0.2 0.0 0.1 0.0 0.0 114.3 32.5 0.0 0.0 0.0 0.6 0.3 0.1 0.0 89.9 0.0 0.0 0.0 101.6 182.1 0.0 503.4 0.0 0.0 0.3 388.9 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 0.0 86.0 0.1 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC37A2 FLJ00171 ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 78.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.4;Hofbauer cells: 36.5;Kupffer cells: 22.0;Macrophages: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.2" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.2" "Cell line enhanced" "Detected in many" "A-431: 33.8;CAPAN-2: 70.3;hTCEpi: 34.9;hTERT-HME1: 64.8;U-138 MG: 47.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" 4.2 24.2 1.7 16.9 2.6 1.4 4.6 2.4 3.7 2.3 2.1 8.0 9.1 1.0 1.3 13.4 1.2 5.1 1.5 1.9 2.3 0.7 5.9 5.9 5.7 4.3 2.7 1.0 1.2 1.1 0.2 7.4 3.8 2.6 10.2 0.5 78.8 1.4 0.6 20.9 7.7 3.1 3.2 15.8 2.1 1.6 5.2 2.1 0.6 0.9 5.1 11.9 7.7 7.3 33.8 0.1 1.0 0.4 0.6 0.8 0.6 1.6 2.8 1.0 2.5 0.2 70.3 0.4 9.4 0.4 2.5 21.0 0.4 20.9 3.8 0.9 0.6 6.6 1.6 2.4 0.1 0.3 0.9 0.7 34.9 2.6 64.8 2.7 1.7 1.3 0.5 2.2 3.1 0.3 0.3 4.6 1.9 0.2 1.0 0.4 2.7 0.8 1.0 17.6 0.3 0.3 4.8 2.9 2.6 0.5 0.3 1.8 3.7 47.2 1.9 0.7 1.6 1.8 1.5 1.1 1.7 2.4 4.1 0.2 12.3 0.0 0.0 14.1 0.0 0.4 0.0 0.1 5.5 0.1 0.1 0.1 1.3 0.0 19.2 0.2 0.0 5.4 1.7 2.6 2.4 3.7 1.9 2.3 4.3 2.7 3.8 3.2 5.2 7.3 0.7 0.0 0.6 0.3 3.8 0.3 1.4 0.5 1.2 1.5 1.4 1.1 1.1 1.5 1.6 0.0 2.1 0.6 0.7 13.4 0.0 0.1 1.6 1.9 1.4 1.3 0.0 2.7 0.3 0.0 0.8 0.5 0.0 4.9 2.5 0.4 1.8 0.3 36.5 0.0 0.3 0.1 0.0 22.0 1.4 2.2 0.9 22.7 0.0 8.4 7.3 0.3 3.1 1.0 0.2 0.1 3.3 1.2 1.7 1.0 0.0 0.1 0.2 0.8 0.0 0.8 0.6 2.7 1.1 5.7 0.9 3.4 1.2 0.4 0.1 3.2 SLC37A3 DKFZp761N0624 ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" 19.2 10.2 10.6 10.6 11.5 12.3 21.5 10.9 14.0 30.2 7.4 26.4 14.1 44.0 23.9 11.4 23.4 19.1 12.8 10.8 11.3 15.8 12.8 16.5 9.1 10.3 9.3 20.7 25.7 35.0 17.1 21.8 10.6 14.7 24.5 11.3 23.3 12.7 7.8 13.5 16.4 31.9 8.9 15.7 18.4 7.4 11.7 11.7 21.3 9.9 10.6 22.1 18.3 11.0 18.0 29.9 30.3 53.3 42.7 46.6 36.2 26.3 30.8 17.9 26.6 23.9 38.1 2.7 32.6 24.0 45.8 14.5 18.5 32.0 27.3 40.6 27.1 3.5 7.8 24.1 35.9 0.2 9.7 36.8 32.3 19.0 22.0 31.2 27.9 15.5 18.2 7.3 27.8 34.3 17.5 1.6 44.9 43.2 18.4 9.5 8.1 8.2 34.5 37.0 29.8 36.7 7.3 29.5 29.7 32.3 15.9 1.7 32.0 20.4 14.8 51.8 27.3 14.0 28.4 6.9 21.6 0.2 47.7 7.6 3.6 3.7 6.5 2.0 3.5 2.3 6.9 5.1 3.0 1.7 7.3 5.5 12.3 5.9 1.3 0.9 8.6 3.6 10.6 11.5 10.9 14.0 10.8 11.3 10.3 9.3 10.6 8.9 11.7 11.0 8.5 9.6 12.4 14.4 6.0 15.2 39.8 11.8 8.6 11.4 12.1 8.6 5.1 10.0 16.1 12.9 10.4 17.5 5.8 21.0 1.9 22.3 1.6 24.9 43.8 11.6 21.6 6.1 37.1 26.9 26.4 30.6 19.9 21.3 8.2 15.0 13.2 7.3 4.0 13.5 29.0 22.2 14.2 5.1 9.7 2.3 20.2 3.3 19.6 13.1 7.4 3.6 11.3 26.7 22.4 28.6 14.7 13.5 4.2 31.4 11.2 5.7 18.4 9.0 6.6 15.1 16.9 4.6 5.9 8.5 12.4 13.1 10.6 5.1 18.1 37.4 SLC38A1 "ATA1, NAT2, SAT1" ENSG00000111371 "Solute carrier family 38 member 1" Q9H2H9 12 46183063-46270017 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 443.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 386.1" "Low region specificity" "Detected in all" "HPA039460, HPA052272" Uncertain Supported NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "HPA039460: , HPA052272: AB_2681781" "unprognostic (8.92e-3)" "unprognostic (3.23e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (1.00e-1)" "unprognostic (3.74e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (2.01e-3)" "unprognostic (1.38e-1)" "unprognostic (4.19e-3)" "unprognostic (2.44e-2)" "unprognostic (3.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (3.00e-1)" "unprognostic (5.55e-2)" 8.2 5.3 20.0 38.5 18.6 26.0 81.8 48.2 18.9 13.6 0.6 39.3 16.7 16.4 8.7 26.6 15.5 16.6 44.6 15.3 42.3 20.3 6.4 13.2 64.4 44.1 25.4 9.9 23.8 78.7 19.3 22.5 34.6 29.5 38.5 79.0 20.5 35.6 90.7 30.5 22.9 27.8 48.4 31.9 21.3 1.1 26.8 59.5 42.5 82.4 54.4 23.4 11.2 59.7 77.6 79.2 28.2 104.9 12.4 4.5 142.8 60.6 98.2 27.3 42.7 136.6 74.9 176.3 113.0 74.7 83.6 116.5 94.8 124.5 50.4 109.6 49.8 12.3 127.4 51.2 108.3 126.1 4.5 21.7 186.7 8.2 325.1 67.5 61.6 112.0 65.2 144.2 86.5 96.5 112.7 22.0 104.1 0.1 122.7 99.8 6.9 124.6 105.4 109.8 111.6 77.2 126.2 152.9 71.7 108.0 88.9 91.1 129.8 21.2 19.7 0.6 62.7 136.2 126.5 386.1 67.9 242.2 18.6 1.0 0.8 26.3 51.8 0.2 71.0 50.4 54.1 61.0 34.9 57.8 62.6 57.1 2.4 68.3 0.4 44.3 63.5 46.4 20.0 18.6 48.2 18.9 15.3 42.3 44.1 25.4 34.6 48.4 26.8 59.7 10.3 35.3 44.7 75.4 150.0 97.8 73.8 103.8 30.1 443.5 136.5 64.8 207.5 38.6 61.8 213.3 141.8 106.9 216.3 99.3 3.9 56.3 0.2 78.1 9.8 26.7 40.6 25.6 104.7 46.4 79.3 14.6 19.4 123.7 3.8 30.9 5.7 6.1 12.2 8.4 157.8 73.6 79.3 12.9 76.1 0.3 2.1 23.3 26.6 30.9 13.6 51.4 107.1 94.5 59.7 53.5 52.8 0.7 138.8 66.5 23.6 1.1 29.7 54.2 0.0 62.9 34.5 0.1 0.4 70.3 122.7 185.7 167.9 1.6 93.6 75.4 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 132.0;prostate: 83.0;stomach 1: 83.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 546.0;Exocrine glandular cells: 213.4;Intestinal goblet cells: 327.8;Paneth cells: 299.3;Proximal enterocytes: 267.7;Respiratory ciliated cells: 406.7;Undifferentiated cells: 259.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" 0.8 8.2 0.0 2.5 0.0 1.0 5.3 0.0 0.0 22.4 0.0 132.0 100.8 5.9 2.5 2.0 46.9 18.8 0.0 0.0 0.0 32.1 0.4 14.9 0.1 0.3 0.1 1.6 8.9 0.0 16.1 3.5 0.1 83.0 30.3 0.0 42.6 3.9 0.0 1.1 86.8 2.9 0.0 1.6 83.4 0.7 0.0 0.2 1.9 0.0 0.7 11.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 3.7 22.4 36.0 0.0 3.8 0.5 23.0 71.4 0.6 0.3 14.6 6.1 0.4 38.6 180.2 66.2 0.0 0.3 0.5 546.0 3.9 111.2 2.3 127.4 8.9 6.2 46.7 0.0 0.1 213.4 0.5 2.4 208.5 67.5 2.5 1.1 0.4 0.0 0.5 0.0 0.1 327.8 91.6 0.0 0.0 3.2 1.5 2.5 0.0 0.0 1.6 0.7 0.0 0.0 0.0 184.0 299.3 0.4 0.3 142.0 267.7 61.5 406.7 0.6 0.0 0.8 11.9 0.2 0.2 0.5 0.4 0.7 2.3 5.5 259.6 139.4 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC47A2 "FLJ31196, MATE2, MATE2-K" ENSG00000180638 "Solute carrier family 47 member 2" Q86VL8 17 19678288-19718979 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.3;choroid plexus: 39.6;kidney: 55.8" "Cell type enriched" "Detected in some" 4 "Proximal tubular cells: 91.3" "Cancer enhanced" "Detected in some" "glioma: 2.6;renal cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTCEpi: 2.1" "Not detected" "Not detected" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (4.52e-3)" "unprognostic (8.28e-3)" "unprognostic (1.54e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (8.95e-4)" "unprognostic (5.22e-2)" "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (3.29e-2)" "unprognostic (1.51e-1)" "unprognostic (1.36e-3)" "unprognostic (7.77e-2)" "unprognostic (1.04e-3)" "unprognostic (4.33e-2)" "unprognostic (1.61e-1)" "unprognostic (6.44e-2)" "unprognostic (5.71e-2)" 0.1 0.2 2.5 0.0 2.1 0.0 0.2 2.0 1.5 0.1 39.6 0.0 0.0 0.1 6.7 0.4 10.0 0.0 0.1 3.5 6.4 55.8 0.0 0.0 0.0 11.6 22.3 0.1 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.6 0.4 0.2 1.1 2.3 0.3 0.1 8.4 0.0 0.0 0.0 5.0 0.0 0.2 0.2 0.0 0.0 0.1 4.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.1 2.0 1.5 3.5 6.4 11.6 22.3 11.5 8.4 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.6 0.0 0.0 0.9 0.7 0.0 0.2 5.5 0.0 0.1 0.0 0.2 5.9 0.0 0.6 20.9 0.4 0.1 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 2.0 0.0 0.0 0.7 0.3 0.9 0.0 1.9 0.0 1.3 0.0 2.0 1.4 0.1 0.0 0.0 0.0 0.8 1.7 91.3 2.5 0.5 0.0 3.5 0.1 0.6 0.8 1.0 0.3 0.0 0.6 0.0 0.2 0.2 SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 819.1;Cholangiocytes: 133.0;Distal enterocytes: 282.9;Ductal cells: 129.2;Proximal tubular cells: 211.0" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 6.1;HBF TERT88: 5.7;hTERT-RPE1: 6.0;RPTEC TERT1: 15.4;U-138 MG: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" 5.1 0.7 30.0 2.2 43.6 0.5 1.0 47.0 32.5 11.5 0.0 41.1 54.3 0.4 0.3 1.2 0.9 29.4 6.2 21.5 37.9 119.5 21.7 6.9 0.2 38.6 28.0 0.8 260.3 17.2 5.8 2.7 24.8 34.7 41.2 5.1 2.5 1.1 2.2 0.1 14.6 1.7 38.2 0.8 18.6 0.5 38.5 3.5 22.0 3.5 0.0 4.5 0.4 33.2 0.0 3.5 1.0 0.0 0.0 0.0 0.1 13.0 1.9 2.2 1.6 0.0 0.1 0.0 0.1 6.1 0.5 0.0 0.2 0.0 5.7 0.0 1.7 0.9 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.7 0.0 0.5 1.2 0.0 4.8 0.2 0.1 0.2 0.0 0.0 0.0 0.9 15.4 4.1 0.9 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.0 7.7 0.7 5.5 0.6 0.0 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 30.0 43.6 47.0 32.5 21.5 37.9 38.6 28.0 24.8 38.2 38.5 33.2 1.5 3.2 37.1 819.1 2.2 0.0 4.3 3.2 0.6 3.2 0.9 0.3 24.0 133.0 31.1 25.8 0.0 0.3 7.2 282.9 15.6 129.2 11.5 2.8 0.5 1.3 8.5 4.0 51.4 24.2 0.1 4.9 33.1 5.8 1.3 0.6 3.9 35.8 0.2 0.0 93.4 65.6 2.0 0.6 0.2 1.5 0.0 2.3 1.8 34.7 1.0 3.9 1.0 29.1 3.7 16.2 60.8 0.0 1.7 40.8 31.8 211.0 10.4 1.5 6.6 1.0 6.2 0.1 1.0 5.5 0.0 0.3 6.8 2.4 68.1 12.3 SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.8;intestine: 107.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 354.6;Paneth cells: 145.1;Proximal enterocytes: 721.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 18.5;EFO-21: 11.9;Hep G2: 15.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" 0.7 1.1 5.8 3.5 5.5 0.8 0.3 4.0 3.9 41.8 0.0 41.9 86.9 3.0 0.3 2.4 3.6 2.8 2.3 3.8 6.5 19.5 2.2 6.1 0.6 7.3 10.9 1.1 0.3 0.0 0.4 0.6 7.7 2.7 29.4 0.7 1.0 0.6 1.0 0.8 107.1 1.7 6.5 0.8 0.8 9.6 11.8 0.0 0.7 0.0 0.0 1.5 0.9 4.2 0.0 1.5 0.2 0.8 0.0 0.1 0.4 0.0 0.0 0.2 0.0 18.5 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 15.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.4 0.1 0.4 0.4 0.1 0.4 0.0 0.0 0.9 0.4 0.0 0.6 0.5 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.5 4.0 3.9 3.8 6.5 7.3 10.9 7.7 6.5 11.8 4.2 0.0 0.0 1.1 0.3 1.3 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.1 0.0 354.6 13.7 0.0 60.8 10.4 0.2 1.2 1.8 2.7 0.0 0.0 0.0 0.5 0.0 1.9 4.5 0.0 0.4 1.8 0.1 0.0 0.0 23.0 0.0 0.3 0.0 14.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.1 0.0 0.0 0.0 721.4 73.3 15.6 0.0 6.6 1.0 0.4 27.9 0.5 0.0 0.0 0.1 0.6 0.1 45.8 0.0 SLC7A13 "AGT-1, XAT2" ENSG00000164893 "Solute carrier family 7 member 13" Q8TCU3 8 86214063-86321146 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 234 "kidney: 42.0" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (1.12e-1)" "unprognostic (2.96e-5)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLCO2B1 "OATP-B, OATP2B1, SLC21A9" ENSG00000137491 "Solute carrier organic anion transporter family member 2B1" O94956 11 75100563-75206549 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 229.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 204.5;Hofbauer cells: 122.2;Kupffer cells: 155.8;Macrophages: 92.4;Microglial cells: 232.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 90.3;GAMG: 21.2;Hep G2: 20.4;HMC-1: 25.8;OE19: 111.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020659 Uncertain NA NA "Cluster 15: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 4: Macrophages - Innate immune response" "HPA020659: AB_1857219" "unprognostic (8.25e-2)" "unprognostic (5.30e-2)" "unprognostic (2.02e-2)" "unprognostic (3.57e-1)" "unprognostic (3.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (2.61e-1)" "unprognostic (2.00e-3)" "unprognostic (1.99e-1)" "unprognostic (2.09e-1)" "unprognostic (9.75e-3)" "unprognostic (2.54e-2)" "unprognostic (4.57e-3)" "unprognostic (1.04e-1)" "unprognostic (3.87e-2)" 39.9 31.5 40.1 34.0 35.9 2.9 12.1 34.0 37.4 18.1 21.3 30.9 42.1 9.5 3.6 19.7 13.2 28.4 15.6 31.9 47.2 21.0 229.6 60.7 60.1 75.7 53.4 9.4 22.1 7.9 5.1 43.9 63.0 6.1 23.6 1.5 8.4 9.6 5.6 4.3 51.3 26.3 49.7 46.4 15.0 6.0 80.4 16.7 10.1 8.0 28.5 26.3 6.2 55.1 0.0 0.7 2.8 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 90.3 0.0 0.1 0.1 0.0 21.2 0.2 0.0 0.0 0.0 1.1 0.0 15.0 1.0 20.4 0.0 1.1 25.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.3 8.7 0.0 0.1 0.0 0.1 0.1 111.1 0.0 0.0 2.4 9.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.3 0.0 1.5 1.8 0.0 1.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.1 35.9 34.0 37.4 31.9 47.2 75.7 53.4 63.0 49.7 80.4 55.1 4.7 0.0 8.9 1.3 0.7 1.9 0.0 0.0 1.8 3.4 0.9 1.4 2.8 11.5 1.8 0.0 0.0 0.9 0.1 14.7 1.9 0.0 2.8 0.0 0.1 28.8 0.0 2.7 0.5 0.2 2.3 3.6 0.5 0.0 22.9 6.1 3.6 204.5 122.2 0.0 0.5 6.6 0.0 155.8 8.9 1.7 10.8 92.4 0.0 232.3 2.0 0.2 0.0 1.5 0.6 0.1 14.6 10.5 1.4 0.0 46.7 8.2 0.7 0.7 0.0 3.0 1.1 0.4 0.2 4.5 0.4 2.5 0.7 0.4 13.3 0.1 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMIM12 "C1orf212, FLJ90372" ENSG00000163866 "Small integral membrane protein 12" Q96EX1 1 34712737-34859755 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065331 Approved Approved Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA065331: AB_2685470" "unprognostic (2.21e-1)" "unprognostic (2.26e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (2.64e-1)" "unprognostic (2.05e-1)" "unprognostic (5.71e-2)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "prognostic favorable (1.15e-5)" "unprognostic (7.33e-2)" "unprognostic (6.70e-2)" "unprognostic (3.58e-2)" "unprognostic (2.52e-2)" 40.2 56.6 31.7 26.5 32.1 24.8 33.5 29.5 35.3 20.9 29.2 34.0 30.1 26.0 17.7 41.3 23.5 17.3 53.8 31.5 35.7 42.3 87.9 31.6 25.0 32.6 32.7 17.1 26.4 31.8 26.9 24.8 33.1 19.9 28.0 12.8 24.1 20.5 56.2 29.7 30.8 31.5 29.6 31.9 30.4 28.0 31.9 30.3 24.9 51.1 27.3 29.2 25.7 33.3 52.9 39.8 43.3 31.6 55.2 43.3 30.1 55.8 48.1 70.2 60.3 40.0 65.0 55.1 49.2 57.6 55.5 51.7 55.5 74.7 53.5 67.3 41.6 98.1 65.6 49.1 51.3 107.9 55.4 66.2 71.9 76.5 61.3 25.3 72.9 47.0 71.0 72.3 63.0 38.6 52.6 55.4 70.1 40.8 52.7 44.1 42.7 71.7 62.2 54.6 41.5 32.9 52.0 48.1 81.5 53.9 32.8 29.9 69.9 47.8 49.3 74.3 66.7 40.4 60.2 56.9 45.2 63.7 32.1 104.2 76.0 126.4 65.8 82.0 77.9 57.7 60.4 72.0 86.0 59.2 50.1 64.3 50.2 62.6 67.5 62.4 76.2 87.5 31.7 32.1 29.5 35.3 31.5 35.7 32.6 32.7 33.1 29.6 31.9 33.3 51.2 25.6 13.1 4.9 37.0 68.2 26.3 49.8 23.3 14.4 36.4 30.1 33.9 42.9 30.4 22.0 10.4 50.7 38.5 46.7 86.1 78.7 58.3 17.1 19.0 56.2 21.8 53.9 10.4 83.7 60.2 24.9 20.9 20.6 23.5 18.9 48.2 89.3 83.8 20.2 9.5 23.4 46.8 41.7 61.6 32.7 14.9 41.0 39.2 7.5 89.8 24.9 54.6 6.6 7.0 87.5 41.0 23.3 27.5 40.8 62.9 90.6 26.8 17.3 13.1 21.8 52.3 37.6 23.0 41.4 75.6 58.0 40.8 33.7 39.6 41.7 SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.6;pancreas: 154.3;salivary gland: 147.2;stomach 1: 201.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2005.0;Intestinal goblet cells: 1223.5;Paneth cells: 1462.9;Proximal enterocytes: 1685.8;Respiratory ciliated cells: 686.7;Undifferentiated cells: 775.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 261.7;OE19: 247.3;RT4: 89.8;SCLC-21H: 70.7;SK-BR-3: 201.2" "Low region specificity" "Detected in many" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" 1.2 0.3 0.1 14.6 1.2 3.5 48.2 4.6 2.0 45.4 0.0 193.6 129.6 8.9 50.4 10.3 77.3 33.3 0.5 0.5 0.4 42.0 1.4 24.1 0.6 2.6 0.9 0.5 154.3 0.1 48.9 2.0 2.1 42.6 122.7 1.5 147.2 36.3 0.2 10.4 128.4 6.3 0.8 0.2 201.7 33.8 2.6 0.2 1.1 0.0 2.7 46.1 6.5 3.1 0.2 0.0 0.1 0.6 0.0 0.0 1.9 0.3 0.1 0.1 0.1 0.6 261.7 0.3 7.3 0.0 0.3 1.3 0.1 0.0 0.1 0.4 1.9 0.1 5.8 0.9 0.1 0.7 0.3 0.2 1.4 0.0 0.0 0.2 0.1 0.4 0.0 0.6 0.0 1.9 0.1 0.6 0.8 247.3 0.0 0.8 0.3 23.6 1.5 89.8 70.7 0.8 0.5 201.2 0.0 0.5 15.2 0.0 0.0 0.6 0.8 1.1 0.1 0.2 0.6 0.9 0.0 0.7 0.6 1.2 0.3 0.4 0.3 0.1 0.1 0.1 0.3 0.1 0.0 0.4 0.3 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.1 1.2 4.6 2.0 0.5 0.4 2.6 0.9 2.1 0.8 2.6 3.1 1.4 48.1 117.7 0.0 5.8 2.2 22.7 92.7 0.0 4.2 363.3 267.5 0.5 183.0 154.9 250.1 0.0 3.9 3.0 2005.0 25.4 259.8 40.1 430.4 26.5 4.4 470.3 0.0 0.5 381.9 0.4 4.7 438.8 258.3 18.4 0.1 0.4 0.2 0.4 1.7 0.3 1223.5 152.5 0.0 0.8 107.3 0.6 4.2 23.2 0.0 5.3 0.6 0.0 0.0 1.3 539.9 1462.9 1.2 1.0 29.5 1685.8 99.4 686.7 4.2 0.0 0.0 15.9 38.6 0.6 2.3 2.3 3.7 6.6 0.2 775.6 148.6 SNAI3 "SMUC, Zfp293, ZNF293" ENSG00000185669 "Snail family transcriptional repressor 3" Q3KNW1 16 88677688-88686507 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 31.3" "Cell type enhanced" "Detected in some" "dendritic cells: 19.7;granulocytes: 9.5;Kupffer cells: 14.6;Langerhans cells: 9.3;Macrophages: 9.4;NK-cells: 17.5;Plasma cells: 14.0;T-cells: 14.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NB-4: 18.2;RPMI-8226: 28.6" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Not detected" "Not detected" HPA071127 Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA071127: AB_2686346" "unprognostic (1.03e-2)" "prognostic favorable (1.39e-4)" "unprognostic (2.20e-2)" "unprognostic (6.19e-4)" "unprognostic (3.05e-1)" "unprognostic (2.85e-3)" "unprognostic (2.60e-1)" "unprognostic (1.98e-3)" "unprognostic (3.24e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.58e-4)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" "unprognostic (8.46e-2)" "unprognostic (6.57e-2)" "unprognostic (1.11e-1)" "unprognostic (7.47e-2)" 0.7 0.5 1.5 2.4 2.4 1.8 0.4 0.0 3.3 0.6 0.0 1.2 1.5 0.6 0.3 0.6 0.8 1.0 2.4 1.9 0.0 0.7 0.8 2.2 3.9 2.1 0.0 0.5 1.7 1.5 0.7 0.1 3.7 0.8 0.3 0.3 1.2 0.2 31.3 0.6 3.7 0.2 0.0 6.9 3.3 0.9 0.0 0.8 0.9 7.3 2.6 1.4 0.5 0.0 0.3 0.9 0.3 1.3 0.0 0.0 0.6 0.3 0.0 0.0 0.1 3.5 0.3 2.3 0.5 0.0 0.8 0.8 0.3 0.2 0.0 0.4 1.2 1.1 0.1 1.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.5 2.1 4.3 0.0 3.2 0.2 18.2 0.4 0.3 0.4 3.9 0.3 28.6 0.0 0.4 1.7 0.2 0.7 0.0 0.2 0.4 1.2 2.2 0.3 0.1 1.0 0.2 0.0 0.7 4.2 4.0 0.3 4.9 0.5 5.2 14.1 48.5 10.2 5.3 18.8 7.8 16.7 9.8 16.7 6.1 10.0 6.4 30.9 1.1 1.5 11.9 21.4 10.9 1.5 2.4 0.0 3.3 1.9 0.0 2.1 0.0 3.7 0.0 0.0 0.0 0.3 3.2 0.0 2.0 8.5 0.5 0.1 0.4 0.0 0.2 0.4 0.5 2.0 0.0 0.7 0.0 0.0 0.0 19.7 0.0 1.9 0.1 0.0 0.6 0.0 0.4 0.0 0.4 6.4 0.4 0.5 0.2 0.5 0.1 9.5 0.0 0.4 0.1 6.9 0.0 3.7 0.1 2.0 14.6 9.3 0.3 0.0 9.4 5.4 0.0 5.3 0.1 17.5 1.0 1.9 0.1 1.1 0.4 14.0 0.1 0.0 0.2 1.0 0.9 0.0 0.7 0.4 0.0 1.5 0.2 0.3 0.1 14.0 0.0 0.3 0.1 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 285.7;Hofbauer cells: 148.7;Kupffer cells: 215.5;Macrophages: 166.5;monocytes: 152.3;Muller glia cells: 310.5;Proximal tubular cells: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 336.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 103.1;U-937: 87.3;WM-115: 297.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015605, HPA064782" Approved Supported Nucleoplasm,Nucleoli,Microtubules NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Microtubules" Nucleoli "HPA015605: AB_1857342, HPA064782: AB_2685349" "unprognostic (6.42e-2)" "unprognostic (2.72e-3)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.92e-2)" "unprognostic (2.48e-3)" "unprognostic (4.51e-2)" "unprognostic (4.87e-1)" "unprognostic (9.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (8.06e-5)" "unprognostic (1.12e-2)" "unprognostic (3.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.50e-1)" 23.7 14.5 26.4 34.7 27.8 42.1 11.0 17.6 45.9 4.5 6.1 5.6 4.1 9.0 1.1 2.9 3.0 8.8 1.8 30.2 42.2 37.8 69.1 41.2 36.9 29.1 28.2 1.1 7.8 1.3 4.7 10.9 40.3 3.5 6.4 47.1 1.7 2.1 1.0 1.4 6.2 9.5 18.6 42.1 3.9 5.1 32.0 15.8 2.9 2.7 24.8 10.9 1.6 26.8 55.8 5.0 0.2 10.1 0.1 0.0 57.8 0.0 3.9 0.1 0.0 0.5 18.4 24.0 41.4 0.0 36.2 1.7 13.5 3.6 0.0 33.3 12.4 2.5 0.4 36.3 0.1 52.2 8.9 0.6 5.4 0.0 4.2 0.1 0.8 30.7 1.5 0.3 0.0 9.7 22.2 54.3 15.3 0.9 5.1 0.1 0.1 1.3 103.1 12.0 22.5 7.1 11.7 8.5 62.7 18.1 15.2 72.6 0.3 0.1 12.2 0.2 13.7 17.9 15.5 16.4 0.5 87.3 297.4 55.9 144.7 3.7 18.6 158.5 18.2 82.3 13.2 16.4 101.2 71.7 6.9 12.0 336.7 47.7 162.5 37.0 29.6 70.0 26.4 27.8 17.6 45.9 30.2 42.2 29.1 28.2 40.3 18.6 32.0 26.8 3.3 3.2 14.7 6.8 63.4 5.4 1.2 0.7 1.8 20.3 17.6 9.5 1.8 34.3 4.4 23.9 2.1 14.9 18.6 2.5 285.7 66.0 1.3 2.1 40.7 7.6 9.5 19.1 63.1 27.1 111.8 3.4 0.0 2.3 31.1 2.9 2.2 109.8 148.7 35.3 53.4 3.3 0.0 215.5 130.3 2.1 1.2 166.5 8.8 19.7 152.3 310.5 33.0 7.1 8.5 14.1 1.5 0.0 8.0 4.4 4.5 204.9 0.8 23.2 0.0 0.7 4.7 7.1 29.5 0.8 3.0 28.7 31.6 0.9 8.7 1.3 SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 290.2;naive B-cell: 289.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037400 Approved Supported Endosomes,Lysosomes NA NA 150000 "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA037400: AB_10670381" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favorable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" 40.6 31.0 6.0 17.9 6.5 14.2 33.8 9.5 8.5 27.8 6.2 32.6 13.4 28.2 12.5 30.1 29.0 12.8 22.4 6.2 6.5 37.8 28.0 33.7 26.5 6.4 7.0 37.1 31.3 14.1 23.2 19.2 6.5 24.2 14.5 7.1 29.1 10.1 27.0 29.0 34.8 17.9 6.9 52.4 32.9 17.1 7.1 10.4 38.3 7.7 24.0 33.6 26.1 8.5 18.9 14.1 18.7 13.1 27.8 19.0 79.6 6.2 21.1 15.1 24.2 27.1 27.2 18.8 18.5 14.9 37.4 6.1 24.6 16.2 18.0 13.4 12.2 23.3 15.8 29.7 19.7 7.7 10.8 16.1 12.8 9.6 16.6 17.6 16.8 15.4 10.1 14.9 14.0 16.1 5.5 11.6 6.3 22.2 10.7 20.2 14.3 25.4 17.3 33.9 12.0 13.3 16.0 19.8 17.0 46.4 24.2 16.0 10.7 13.7 6.9 19.1 11.7 4.4 14.9 24.4 13.6 32.1 15.6 77.9 78.5 57.0 15.4 89.1 18.3 290.2 25.7 24.2 66.5 289.1 23.6 21.0 34.7 18.5 86.6 20.1 48.7 72.7 6.0 6.5 9.5 8.5 6.2 6.5 6.4 7.0 6.5 6.9 7.1 8.5 48.4 35.3 42.8 33.0 260.8 40.7 46.9 82.3 45.5 43.1 23.8 29.3 34.4 40.0 62.4 80.9 8.4 153.9 36.2 19.9 131.0 69.1 25.5 71.5 44.7 49.0 31.8 34.3 38.5 51.8 244.9 62.1 52.5 52.2 65.1 41.8 89.6 31.4 349.2 26.9 42.2 32.6 69.2 125.8 75.8 15.0 53.4 133.0 33.8 61.8 215.8 71.7 23.7 51.8 51.4 35.7 37.0 53.0 37.5 28.1 57.8 114.7 77.8 38.0 46.0 42.8 74.5 89.1 75.9 32.9 38.9 122.9 47.2 92.4 39.8 37.5 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.4" "Group enriched" "Detected in many" 9 "Adipocytes: 370.9;Endothelial cells: 212.4;Hepatic stellate cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 20.8;NB-4: 35.8;REH: 8.5;TIME: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073703 Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 24: NB-4 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA073703: AB_2686628" "unprognostic (2.51e-1)" "unprognostic (3.23e-1)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (2.71e-2)" "unprognostic (4.35e-3)" "unprognostic (1.62e-1)" "unprognostic (3.45e-2)" "unprognostic (1.33e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-3)" "unprognostic (9.63e-3)" "unprognostic (1.41e-1)" "unprognostic (2.46e-1)" "unprognostic (5.40e-2)" 51.8 14.3 8.9 3.1 6.4 0.0 43.1 6.5 6.3 19.5 1.7 16.3 3.1 38.4 0.3 12.0 29.2 3.7 78.4 4.4 5.5 21.4 5.2 29.1 3.1 10.1 8.0 8.0 8.2 1.3 6.6 5.5 9.5 17.6 0.4 0.0 12.6 1.3 13.9 12.2 17.0 1.5 6.7 22.5 15.6 5.6 9.9 0.8 29.0 3.8 0.5 19.7 21.9 5.4 0.0 0.3 0.0 5.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 0.2 0.3 0.0 0.0 0.5 1.0 0.0 3.0 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 20.8 0.0 3.7 0.0 0.0 0.7 0.0 35.8 0.1 0.0 0.3 8.5 0.0 0.6 0.0 1.4 0.6 0.6 0.3 0.0 0.5 0.0 0.5 1.8 9.6 0.1 2.6 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.4 6.5 6.3 4.4 5.5 10.1 8.0 9.5 6.7 9.9 5.4 370.9 0.0 0.6 0.3 3.7 1.0 0.2 0.0 2.2 0.9 1.9 3.0 8.8 1.5 0.0 1.8 0.0 0.0 1.6 0.1 0.0 0.3 22.1 1.0 11.9 212.4 0.0 2.7 0.0 0.0 0.0 2.5 0.0 0.7 4.5 0.0 306.6 0.6 0.1 0.0 0.0 0.0 0.0 6.0 2.2 4.8 1.2 1.3 1.8 15.9 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 3.6 6.5 32.4 2.5 0.9 1.1 0.3 0.7 2.3 0.0 0.3 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SP140L ENSG00000185404 "SP140 nuclear body protein like" Q9H930 2 230327184-230403732 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA055864 Uncertain Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055864: AB_2682949" "unprognostic (1.44e-2)" "unprognostic (8.91e-2)" "unprognostic (4.44e-2)" "unprognostic (9.70e-3)" "unprognostic (2.07e-1)" "unprognostic (1.42e-2)" "unprognostic (1.22e-3)" "unprognostic (1.77e-1)" "unprognostic (3.87e-1)" "unprognostic (2.31e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-1)" "prognostic unfavorable (5.09e-10)" "unprognostic (9.15e-2)" "unprognostic (7.81e-2)" "unprognostic (9.49e-2)" "unprognostic (2.00e-3)" 9.4 9.7 3.4 18.8 3.6 13.6 8.5 3.2 3.9 7.6 4.5 8.5 11.0 7.1 6.4 7.7 7.8 8.6 5.3 3.2 3.6 9.6 15.1 11.3 24.8 5.0 4.1 11.8 4.4 1.6 3.4 10.6 4.6 6.9 9.4 1.9 12.5 6.0 5.1 3.0 16.3 6.5 4.0 25.6 8.9 1.7 4.6 12.8 5.4 4.4 20.2 10.7 8.3 4.7 13.6 2.4 3.1 9.6 15.8 17.2 17.2 19.7 22.6 16.0 25.5 1.3 15.3 10.3 20.2 15.4 28.4 2.3 0.0 14.1 26.0 27.1 0.1 18.5 11.1 10.0 29.7 15.1 19.9 14.4 7.6 23.6 15.4 13.7 23.7 15.5 4.5 9.4 29.0 7.5 22.7 21.2 10.7 9.1 7.0 7.8 28.9 8.3 14.5 16.9 0.6 2.9 4.7 9.5 11.2 19.0 14.2 15.9 26.1 14.2 10.5 8.2 15.2 13.7 9.2 14.8 18.9 15.4 25.2 21.4 7.7 4.1 15.4 10.7 18.7 29.5 14.1 12.5 8.3 32.6 19.5 17.4 7.4 23.0 12.5 3.3 9.7 9.6 3.4 3.6 3.2 3.9 3.2 3.6 5.0 4.1 4.6 4.0 4.6 4.7 30.5 32.1 35.6 1.6 58.8 1.9 13.8 14.6 1.8 2.7 9.3 9.1 4.2 11.5 21.7 16.5 18.8 9.9 40.4 16.8 0.0 22.5 16.3 7.2 16.9 23.3 3.6 9.9 2.4 18.3 17.6 14.6 23.0 14.3 42.3 18.7 13.9 9.4 20.4 0.0 2.0 10.4 16.2 17.1 11.4 5.9 4.4 23.9 5.4 29.0 13.9 1.8 49.4 2.5 1.4 20.0 20.3 8.2 33.7 10.3 14.5 3.3 28.3 1.7 6.6 18.8 14.0 0.8 1.9 7.7 2.6 11.9 47.1 31.7 8.5 23.2 SPAG4 "CT127, SUN4" ENSG00000061656 "Sperm associated antigen 4" Q9NPE6 20 35615829-35621094 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 90.1;testis: 32.0" "Group enriched" "Detected in many" 4 "Early spermatids: 177.9;Late spermatids: 139.8;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 26.0;hTERT-RPE1: 18.4;U-87 MG: 47.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048393, HPA061789" Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 55: Plasma cells - Humoral immune response" "HPA048393: AB_2680385, HPA061789: AB_2684609" "unprognostic (1.05e-1)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.09e-5)" "prognostic favorable (9.52e-8)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.05e-1)" "unprognostic (2.56e-3)" "unprognostic (1.21e-2)" "unprognostic (2.29e-1)" "unprognostic (4.77e-2)" "unprognostic (4.49e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.59e-2)" "unprognostic (1.66e-1)" "unprognostic (1.79e-1)" "prognostic favorable (6.66e-4)" 3.1 5.3 2.3 3.1 2.9 5.0 2.3 2.0 4.4 3.7 2.8 7.0 6.5 2.2 5.5 2.1 4.6 4.2 3.2 2.0 2.7 5.1 4.8 3.1 3.2 3.7 3.7 8.5 90.1 3.1 8.2 1.4 3.6 3.7 2.6 5.4 7.2 2.2 0.6 0.6 5.9 1.4 2.0 12.3 7.3 32.0 2.2 0.9 2.2 0.1 5.5 6.9 2.5 2.2 3.8 1.6 0.8 2.0 2.0 0.7 10.5 1.4 1.9 1.5 2.2 3.4 8.3 0.3 26.0 2.1 6.0 1.0 0.5 5.2 1.6 4.1 0.5 2.9 3.2 3.7 10.2 2.2 4.7 4.9 1.1 1.6 1.2 18.4 3.1 0.9 0.8 7.0 3.9 8.0 0.8 5.4 0.1 7.2 6.9 0.6 0.7 11.4 2.7 1.6 0.6 3.9 1.8 1.2 3.0 0.3 5.2 0.9 3.3 7.2 1.1 1.6 1.5 13.8 5.7 3.2 47.4 0.8 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.4 0.0 2.3 2.9 2.0 4.4 2.0 2.7 3.7 3.7 3.6 2.0 2.2 2.2 3.2 0.0 0.5 0.3 26.6 0.4 1.0 6.3 1.2 3.2 1.7 1.5 2.3 0.0 7.6 0.0 2.1 2.0 7.6 0.6 0.0 13.2 177.9 7.5 2.3 3.4 4.2 0.4 1.9 7.6 15.9 3.3 5.1 6.0 4.5 0.9 5.7 6.7 1.5 1.7 1.2 1.7 24.4 1.4 2.1 139.8 1.8 2.0 26.6 1.9 2.1 14.7 0.0 0.0 0.3 15.5 1.4 3.0 138.0 1.6 0.3 6.0 19.3 2.5 0.0 1.0 3.6 35.0 4.9 0.4 0.1 20.2 7.2 2.3 0.8 3.9 SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 63.5;fallopian tube: 49.0;testis: 96.3" "Cell type enhanced" "Detected in some" "Early spermatids: 228.6;Endometrial ciliated cells: 73.2;Respiratory ciliated cells: 266.4;Spermatocytes: 372.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 29 "U-937: 105.6" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 11.1" HPA038440 Enhanced NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA038440: AB_10671742" "unprognostic (5.02e-2)" "unprognostic (9.52e-2)" "unprognostic (8.94e-6)" "unprognostic (2.21e-1)" "unprognostic (2.51e-2)" "unprognostic (4.91e-3)" "unprognostic (1.68e-1)" "unprognostic (2.38e-1)" "unprognostic (8.68e-2)" "unprognostic (1.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (1.06e-3)" "unprognostic (3.10e-2)" "unprognostic (2.78e-4)" 0.0 0.0 4.2 0.0 4.0 0.4 1.7 1.9 1.4 1.7 63.5 0.0 0.0 0.2 0.4 0.0 49.0 0.0 0.1 3.3 5.0 0.3 0.1 7.0 0.1 17.6 16.1 0.1 0.3 1.8 14.6 0.0 9.9 1.0 0.0 5.8 0.0 0.0 0.0 0.3 0.0 0.0 16.3 0.0 0.0 96.3 6.4 0.4 0.1 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.9 2.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 3.6 0.0 0.0 0.0 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.1 1.7 0.8 0.2 0.0 105.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 4.2 4.0 1.9 1.4 3.3 5.0 17.6 16.1 9.9 16.3 6.4 10.1 0.0 0.0 4.8 0.0 0.1 0.1 0.1 14.0 0.0 0.2 0.5 0.3 0.6 0.0 24.5 0.0 0.0 0.1 0.2 0.1 1.9 0.3 228.6 73.2 0.4 0.2 0.0 0.0 7.1 0.0 0.0 0.7 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 3.1 0.0 16.2 0.0 0.2 51.4 5.0 0.5 1.8 4.7 0.0 0.3 0.0 0.5 6.0 0.4 0.0 4.9 0.3 1.8 0.0 1.4 266.4 1.2 0.0 0.0 3.7 372.6 4.8 0.0 0.1 0.0 0.5 0.1 0.0 0.1 SPDEF "bA375E1.3, PDEF" ENSG00000124664 "SAM pointed domain containing ETS transcription factor" O95238 6 34537802-34556333 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 140.7;salivary gland: 114.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 94.2;Breast myoepithelial cells: 61.1;Intestinal goblet cells: 315.1;Prostatic glandular cells: 72.7" "Cancer enhanced" "Detected in many" "prostate cancer: 388.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MCF7: 288.4;OE19: 118.0;SK-BR-3: 192.2;T-47d: 154.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.9" HPA055707 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" Cytosol "HPA055707: AB_2682894" "unprognostic (2.98e-1)" "unprognostic (9.68e-2)" "unprognostic (2.84e-1)" "prognostic favorable (9.26e-9)" "unprognostic (1.57e-1)" "unprognostic (7.10e-3)" "unprognostic (2.56e-2)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (7.39e-3)" "unprognostic (3.48e-3)" "unprognostic (2.92e-1)" "unprognostic (6.16e-11)" "unprognostic (8.04e-2)" "unprognostic (1.85e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-2)" 0.4 0.1 0.5 1.4 0.5 0.1 36.6 0.8 1.1 28.0 0.0 18.4 11.6 9.0 0.5 2.2 6.3 2.4 0.4 0.5 0.2 0.1 0.1 1.1 0.0 0.3 0.4 0.1 0.6 0.0 0.2 0.0 0.2 140.7 10.2 0.0 114.8 0.1 0.3 9.3 14.3 0.6 0.1 0.1 35.4 0.3 0.5 0.0 0.1 0.0 0.0 1.0 0.3 0.5 0.0 30.9 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 288.4 0.3 0.4 0.0 118.0 38.6 0.1 0.0 0.3 0.3 0.3 2.1 0.2 0.0 192.2 0.0 0.0 154.0 0.0 0.0 0.0 0.5 0.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.8 1.1 0.5 0.2 0.3 0.4 0.2 0.1 0.5 0.5 0.8 0.0 2.2 0.7 0.3 0.1 13.3 20.7 0.0 0.0 94.2 61.1 0.3 5.7 31.7 0.0 0.0 0.0 1.4 27.1 0.0 2.6 1.1 6.2 0.7 0.6 5.4 0.0 0.8 1.2 0.0 0.4 28.1 18.7 0.0 0.2 0.4 0.0 0.0 0.0 0.6 315.1 12.2 0.0 0.2 5.5 0.0 0.9 3.6 0.0 0.0 0.0 0.0 0.0 0.2 20.2 12.3 0.0 0.1 72.7 5.7 0.0 2.9 0.0 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.3 0.8 0.0 30.0 11.5 SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.1;Inhibitory neurons: 220.8;Microglial cells: 187.4;Oligodendrocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 42.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 9800 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: AB_1857431, HPA021430: AB_1857432, HPA061073: " "unprognostic (1.13e-3)" "unprognostic (2.39e-1)" "unprognostic (1.98e-2)" "unprognostic (8.10e-3)" "unprognostic (8.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (5.81e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" 12.5 9.6 30.8 7.3 35.1 23.6 9.2 24.1 43.7 6.1 22.3 15.1 9.8 12.8 4.7 9.2 8.3 14.8 5.0 41.4 21.4 4.7 1.2 5.7 5.3 32.8 25.8 16.6 4.8 3.3 6.4 3.6 24.5 6.1 10.0 6.1 6.2 5.0 5.1 3.6 10.5 9.5 21.0 13.5 10.3 22.8 41.1 3.0 5.2 2.8 5.2 4.6 4.3 47.3 26.2 37.3 15.7 7.2 14.7 6.9 29.1 10.0 12.4 12.4 21.4 67.6 17.1 1.5 45.3 11.4 24.3 21.1 10.7 33.4 3.7 12.8 18.5 14.5 34.4 10.5 4.9 1.3 5.6 10.6 36.9 10.2 24.9 46.8 0.0 4.4 1.0 15.1 10.4 24.0 0.3 5.3 14.5 17.0 6.3 11.8 49.5 23.6 32.2 11.4 7.1 6.9 75.7 35.6 13.9 62.2 26.3 9.1 0.3 0.5 21.1 0.9 30.8 5.4 11.7 0.9 19.1 12.6 6.5 42.1 15.8 33.0 2.2 8.4 3.2 1.8 1.5 3.4 26.6 1.4 1.0 1.4 11.1 13.0 7.9 4.6 0.6 5.5 30.8 35.1 24.1 43.7 41.4 21.4 32.8 25.8 24.5 21.0 41.1 47.3 28.7 22.4 14.7 170.4 5.7 5.5 12.5 22.0 10.8 7.4 5.8 4.7 10.3 7.2 21.1 18.4 68.8 5.5 10.2 56.8 9.8 30.9 100.0 40.1 44.1 13.1 7.7 82.5 217.1 36.3 11.5 18.6 34.1 64.1 116.4 29.5 3.9 0.2 22.0 0.0 220.8 54.8 12.2 12.4 15.9 54.5 5.0 29.0 21.4 187.4 84.7 13.6 11.3 125.2 317.8 67.7 24.7 44.8 7.0 19.7 25.2 3.6 18.1 31.4 59.2 7.3 81.3 73.8 68.9 5.9 2.6 2.2 10.0 87.8 27.4 21.5 SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5310.4" "Group enriched" "Detected in many" 10 "Early spermatids: 1217.2;Late spermatids: 1399.4;Spermatocytes: 1989.6" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "NK-cell: 146.4" "Lineage enriched" "Detected in many" 7 "NK-cells: 146.4" "Cell line enriched" "Detected in some" 4 "U-266/70: 90.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB020824, HPA026813" Enhanced "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" 0.5 0.1 0.1 1.1 0.2 13.5 1.3 0.1 0.6 1.3 1.8 2.8 1.9 0.3 5310.4 0.2 0.3 0.1 7.4 0.2 0.2 0.3 0.2 0.2 4.7 0.3 0.3 0.4 0.1 0.0 4.2 0.0 0.2 3.5 2.1 0.0 2.0 240.7 1.8 0.5 3.1 0.3 0.2 1.7 3.0 346.1 0.3 3.9 0.6 2.3 4.8 0.5 4.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.7 2.9 18.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 6.0 0.3 3.0 0.0 0.0 0.2 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 90.5 0.4 0.0 0.0 0.0 0.0 4.4 0.0 1.1 0.5 0.1 0.6 9.1 5.1 5.4 1.4 10.5 11.1 21.6 0.9 146.4 0.0 0.8 0.3 5.4 0.1 0.2 0.1 0.6 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.1 0.2 0.0 0.0 0.0 7.2 2.0 14.2 1.8 1.8 0.0 0.2 0.6 3.4 0.0 0.2 0.0 0.0 0.0 2.5 1.4 0.0 0.0 1217.2 0.2 0.1 1.6 1.8 32.4 0.3 0.0 0.3 0.8 0.5 0.2 1.3 0.3 0.0 0.0 0.1 0.0 0.2 10.4 0.0 0.0 3.6 1399.4 37.9 2.5 12.4 0.0 1.6 1.5 1.0 0.0 0.1 0.0 13.1 24.5 35.2 9.5 0.4 0.3 0.3 0.0 13.1 0.4 1.9 1989.6 149.9 0.1 0.3 0.0 16.8 0.0 2.6 2.6 SPINK8 ENSG00000229453 "Serine peptidase inhibitor Kazal type 8 (putative)" P0C7L1 3 48306842-48328341 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 11.5;breast: 44.1" "Group enriched" "Detected in some" 5 "Breast glandular cells: 22.1;Breast myoepithelial cells: 9.9" "Group enriched" "Detected in some" 10 "breast cancer: 8.6;glioma: 9.6;prostate cancer: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 1.3;neutrophil: 1.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.7" "Cell line enriched" "Detected in some" 60 "SK-BR-3: 73.2" "Region enriched" "Detected in many" 9 "hippocampal formation: 73.7" "Low region specificity" "Detected in all" HPA053151 Uncertain "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "HPA053151: AB_2682059" "prognostic unfavorable (8.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" 0.0 0.0 2.2 0.0 2.2 11.5 44.1 2.6 4.5 0.0 0.4 0.0 0.1 0.0 2.5 2.8 0.2 0.0 0.0 3.0 1.8 0.0 0.0 0.1 0.0 2.9 1.5 0.0 0.4 0.0 0.1 0.2 2.6 0.5 0.0 0.3 2.1 0.3 0.0 0.1 0.0 0.0 1.8 0.6 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.1 0.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 73.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 2.2 2.2 2.6 4.5 3.0 1.8 2.9 1.5 2.6 1.8 2.6 2.9 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 22.1 9.9 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 1.1 0.1 0.0 1.2 0.0 0.0 2.7 1.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 2.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.6 SPSB3 "C16orf31, SSB-3" ENSG00000162032 "SplA/ryanodine receptor domain and SOCS box containing 3" Q6PJ21 16 1776712-1793700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046602 Uncertain Approved Mitochondria NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA046602: AB_2679717" "unprognostic (1.18e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-3)" "unprognostic (1.82e-1)" "unprognostic (8.91e-4)" "unprognostic (1.07e-2)" "unprognostic (8.31e-2)" "unprognostic (5.65e-2)" "unprognostic (8.43e-2)" "unprognostic (3.41e-2)" "unprognostic (4.83e-2)" "unprognostic (5.25e-7)" "unprognostic (2.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.77e-1)" "unprognostic (4.72e-4)" 27.1 44.7 27.9 7.7 28.5 21.2 25.8 37.0 40.2 27.1 24.0 28.9 14.7 21.3 3.3 36.1 23.7 10.0 28.6 26.4 27.2 24.3 41.8 20.6 12.4 29.7 28.3 37.1 44.0 11.4 15.3 10.3 27.4 23.3 5.1 9.6 26.4 15.5 88.5 48.4 18.8 5.6 28.3 23.3 27.8 17.3 29.2 26.1 19.7 31.0 7.8 23.2 28.7 31.8 7.3 9.1 9.7 13.4 13.6 12.5 19.8 10.6 11.0 11.5 12.6 8.4 20.0 3.2 17.4 6.0 4.5 13.9 4.8 10.9 1.8 14.7 15.0 5.2 13.9 10.4 20.2 4.5 12.0 11.3 26.8 7.2 8.4 17.1 17.5 22.1 7.8 15.4 5.4 24.0 16.3 16.0 8.1 10.8 7.1 29.7 5.9 26.7 10.6 1.3 12.9 16.6 12.6 27.8 29.4 6.9 16.1 18.0 16.1 5.6 10.6 10.5 5.5 26.1 28.2 8.9 5.4 8.9 5.9 112.3 44.8 83.4 67.9 41.8 81.2 46.8 63.1 61.7 42.3 44.2 43.6 46.6 91.5 45.7 37.2 42.8 100.7 48.4 27.9 28.5 37.0 40.2 26.4 27.2 29.7 28.3 27.4 28.3 29.2 31.8 74.2 38.5 32.1 29.7 56.1 98.4 53.3 72.7 60.3 74.1 64.1 83.7 0.2 40.0 54.9 55.2 39.6 63.0 104.2 68.6 52.8 50.8 46.7 29.4 32.3 46.1 48.7 50.5 18.2 47.6 74.8 42.8 65.2 37.8 35.4 76.2 57.1 62.5 31.8 90.9 19.4 57.8 38.7 42.7 72.2 91.6 77.0 44.8 76.5 24.4 61.6 76.0 99.9 24.6 30.7 45.3 83.2 74.9 61.2 50.5 96.3 50.6 37.2 89.8 39.5 34.0 45.3 23.8 39.7 37.0 128.3 64.4 87.8 33.2 52.7 54.3 SRARP "C1orf64, ERRF, MGC24047" ENSG00000183888 "Steroid receptor associated and regulated protein" Q8NEQ6 1 16004236-16008807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;breast: 5.1;choroid plexus: 6.2" "Group enriched" "Detected in some" 4 "Breast glandular cells: 25.0;Distal tubular cells: 90.1" "Group enriched" "Detected in some" 4 "breast cancer: 7.7;endometrial cancer: 2.2;prostate cancer: 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.8" "Group enriched" "Detected in some" 13 "Hep G2: 7.9;SK-BR-3: 13.6;T-47d: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026676 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA026676: AB_1853866" "unprognostic (8.55e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.68e-6)" "unprognostic (3.32e-2)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (8.25e-2)" "unprognostic (1.40e-2)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (1.65e-3)" "unprognostic (6.32e-2)" 0.1 0.2 10.3 0.2 9.7 0.7 5.1 8.9 11.3 2.3 6.2 0.1 0.2 1.1 0.1 0.2 0.1 0.2 0.9 8.8 9.3 1.5 0.1 0.1 0.3 9.4 9.4 0.2 0.2 0.0 0.0 0.1 10.0 0.7 0.0 0.8 3.1 0.0 0.2 0.6 0.1 0.0 8.6 0.2 0.3 0.2 11.2 0.0 1.2 0.0 0.0 0.1 0.0 9.2 0.3 0.1 0.3 0.4 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.4 0.6 7.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.6 0.5 0.0 0.4 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.4 0.6 0.3 13.6 0.2 0.4 4.3 0.4 0.2 0.4 0.3 0.3 0.1 0.2 0.5 0.2 0.2 0.2 0.6 0.8 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 0.2 1.8 0.3 0.1 0.1 0.0 0.0 10.3 9.7 8.9 11.3 8.8 9.3 9.4 9.4 10.0 8.6 11.2 9.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.1 0.0 0.0 1.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 8096.7" "Cell type enhanced" "Detected in many" "dendritic cells: 2922.2;granulocytes: 2343.1;Kupffer cells: 1789.9;Langerhans cells: 6618.2;Macrophages: 3639.1;monocytes: 3188.2;Plasma cells: 1740.9;T-cells: 2235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5714.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 5714.1" "Cell line enhanced" "Detected in many" "HL-60: 4442.1;NB-4: 2549.7;THP-1: 4346.8;TIME: 2609.1;U-937: 3546.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" 404.6 114.9 48.8 799.8 50.5 8096.7 136.4 55.5 99.6 93.2 70.1 101.8 77.9 63.5 25.9 91.0 96.8 316.4 111.9 48.2 67.8 98.3 239.4 347.3 437.2 82.4 59.3 30.7 68.4 131.6 62.1 355.6 67.8 58.9 118.9 15.5 40.1 57.4 37.5 18.9 111.4 219.4 65.5 362.8 95.0 18.3 64.7 228.9 72.7 117.1 314.6 508.3 46.1 71.0 5.3 43.0 0.2 0.4 768.1 749.7 1.2 94.9 63.9 235.1 283.5 0.1 18.2 9.1 117.4 4.1 134.4 1.1 0.0 20.6 799.9 535.7 0.4 87.1 29.8 0.3 312.7 4442.1 914.9 306.8 1.1 641.5 39.2 223.8 1227.8 13.3 82.5 419.9 1239.9 0.2 18.7 2549.7 0.7 0.1 84.6 2.4 2.3 446.7 0.6 6.0 0.3 0.8 2.3 0.6 16.0 0.0 2.2 4346.8 2609.1 187.9 12.9 3.8 20.1 486.4 508.4 57.3 112.2 3546.9 1.2 2349.8 1105.3 2730.6 474.9 774.6 313.4 73.5 228.5 362.8 583.0 39.0 125.5 268.4 5714.1 962.8 693.6 631.9 392.6 1590.5 48.8 50.5 55.5 99.6 48.2 67.8 82.4 59.3 67.8 65.5 64.7 71.0 1081.4 112.2 198.1 0.7 592.0 175.9 12.5 38.3 8.6 1.1 16.0 28.2 21.2 21.5 57.5 33.1 0.0 10.2 2922.2 2.9 0.0 4.2 4.1 4.6 15.0 566.8 1.8 277.8 0.2 9.8 10.2 87.9 70.3 6.6 2343.1 0.4 636.1 22.1 847.1 0.0 0.5 1.7 0.0 1789.9 6618.2 8.4 7.5 3639.1 556.7 80.6 3188.2 1.4 1292.5 0.0 0.2 1.3 1.2 18.0 1740.9 12.2 0.3 4.7 45.6 5.0 72.3 22.8 97.5 0.9 2.2 8.7 141.8 14.2 2235.9 1.2 5.5 18.1 SSB "La, La/SSB, LARP3" ENSG00000138385 "Small RNA binding exonuclease protection factor La" P05455 2 169791933-169812064 "Predicted intracellular proteins" RNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004643, HPA017287" Supported Approved Nucleoplasm NA NA 93000 "Cluster 42: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "CAB004643: AB_425691, HPA017287: AB_1852672" "unprognostic (5.58e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (9.05e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.99e-4)" "prognostic unfavorable (8.30e-8)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (9.81e-3)" "unprognostic (3.24e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (6.17e-6)" "unprognostic (9.92e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-3)" "unprognostic (2.38e-2)" 114.1 75.6 53.7 75.8 54.9 105.3 76.0 55.5 72.8 59.3 63.3 61.7 49.2 68.6 82.0 51.6 61.0 58.1 69.0 53.8 58.0 74.5 68.5 55.9 93.3 55.5 58.3 68.9 40.2 80.0 64.6 73.6 55.6 78.2 57.1 55.2 49.9 58.8 62.3 46.6 49.3 61.5 55.3 62.7 49.8 41.1 55.2 70.2 81.7 52.9 81.2 88.4 51.2 55.2 189.0 109.3 231.2 173.5 244.9 226.0 287.8 226.8 150.8 208.2 192.7 332.9 201.7 419.8 251.7 149.8 188.9 197.9 315.3 198.6 283.9 231.2 258.4 505.9 138.0 323.4 218.6 410.8 181.5 175.1 187.1 265.0 156.8 170.6 235.4 156.1 599.0 95.5 442.4 149.5 273.6 428.2 373.3 180.7 110.5 267.9 245.7 304.6 266.3 205.6 219.8 168.0 179.9 132.4 262.9 223.4 152.5 292.0 213.9 151.1 180.1 153.8 221.9 110.3 227.3 355.9 149.2 381.4 168.2 83.4 47.3 59.9 71.9 81.6 104.2 89.8 100.9 92.1 56.8 75.8 90.5 97.0 7.9 93.8 104.5 60.6 100.9 67.2 53.7 54.9 55.5 72.8 53.8 58.0 55.5 58.3 55.6 55.3 55.2 55.2 143.0 86.6 79.9 21.9 107.9 91.6 229.2 308.7 83.6 114.7 78.1 126.7 91.9 77.2 168.9 112.2 27.1 212.4 111.6 33.6 187.9 206.6 20.3 235.3 188.4 131.5 73.0 154.2 25.4 146.7 212.4 133.5 46.9 101.2 205.0 111.4 92.8 77.0 185.7 136.3 26.8 82.7 240.1 86.8 91.4 49.7 184.2 111.7 80.0 15.0 113.4 152.7 84.5 20.1 21.5 113.2 47.8 186.9 78.7 199.2 40.2 194.9 371.1 91.4 216.9 183.7 194.8 154.4 156.7 68.5 88.4 165.4 128.4 183.3 100.0 155.9 SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.1;Enteroendocrine cells: 35.7;Sertoli cells: 32.9;Smooth muscle cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 12.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" 2.5 3.6 8.4 0.9 8.9 0.9 1.7 7.2 8.7 0.5 0.3 0.8 1.4 0.7 1.6 0.4 1.1 0.6 0.8 9.0 4.3 5.3 1.4 0.4 1.1 2.2 5.1 0.3 0.7 0.3 2.9 0.1 8.6 1.4 1.1 2.2 0.7 1.4 0.7 0.6 0.9 0.8 2.6 6.1 3.1 0.3 4.8 0.5 1.1 0.2 1.3 0.9 0.7 6.8 0.2 0.3 0.3 0.7 0.1 0.1 0.4 0.1 0.2 0.3 0.3 0.2 0.3 0.3 0.2 0.1 0.9 0.3 0.0 0.1 0.1 0.4 0.6 0.3 0.8 0.3 0.0 0.2 1.5 0.1 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.7 0.0 0.3 0.2 0.8 1.0 0.1 0.4 0.4 0.4 0.3 0.2 0.3 12.5 0.9 0.2 0.2 0.1 0.5 1.5 0.2 0.1 0.2 1.4 0.4 0.2 0.5 0.2 1.0 0.2 0.3 0.2 1.4 0.2 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.2 0.2 1.2 0.2 0.2 0.2 0.1 0.1 8.4 8.9 7.2 8.7 9.0 4.3 2.2 5.1 8.6 2.6 4.8 6.8 4.9 6.4 2.7 1.6 0.5 1.1 3.2 0.0 0.0 59.1 3.7 2.5 3.6 1.5 1.3 1.8 4.2 0.7 0.9 0.1 0.0 0.2 7.0 2.1 1.7 11.3 35.7 0.0 17.1 0.0 0.7 14.3 3.1 4.9 2.5 3.0 3.9 1.0 1.0 6.7 8.4 8.2 0.0 2.4 3.0 5.7 0.9 2.4 5.4 1.9 1.7 2.4 1.0 2.0 0.7 0.4 0.1 0.7 5.8 5.4 0.6 18.0 0.7 4.8 32.9 10.0 56.0 0.9 1.9 0.3 1.1 1.0 1.4 0.6 0.5 3.3 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 10 "Early spermatids: 501.1;Late spermatids: 1763.3" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.0" "Cell line enhanced" "Detected in some" "BEWO: 25.4;HaCaT: 33.8;HBEC3-KT: 28.5;hTCEpi: 73.1;MCF7: 36.4;SK-MEL-30: 112.5;T-47d: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" 5.6 2.9 1.0 1.9 1.1 1.0 12.2 1.2 1.4 14.9 33.0 13.8 1.0 4.8 10.3 16.4 50.5 1.9 4.5 2.0 1.6 9.6 1.2 17.5 0.6 5.4 6.7 1.2 6.3 7.5 2.1 6.0 4.1 11.1 6.0 52.8 11.3 10.2 18.3 51.6 4.8 2.3 4.2 3.7 7.1 33.9 2.6 1.5 25.2 18.5 4.8 9.5 14.5 2.7 2.6 0.0 0.0 0.0 0.5 0.0 25.4 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.5 1.7 0.1 33.8 0.3 28.5 0.0 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.0 0.0 73.1 0.1 9.0 3.8 0.1 0.0 0.0 0.0 0.4 36.4 0.0 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 9.8 0.5 0.0 4.1 0.1 112.5 1.3 23.4 0.7 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 2.9 5.2 0.0 1.8 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 47.0 0.2 0.4 0.0 0.0 0.4 1.0 1.1 1.2 1.4 2.0 1.6 5.4 6.7 4.1 4.2 2.6 2.7 0.2 0.0 1.5 2.6 0.8 32.9 44.0 104.2 23.9 7.9 0.4 1.5 5.1 7.2 21.0 0.0 27.1 12.5 0.0 2.4 0.0 0.3 501.1 4.5 1.1 3.9 0.0 0.0 0.5 0.0 21.1 2.0 4.6 0.6 1.3 0.0 7.9 1.5 3.0 0.0 1.3 4.8 8.2 5.0 6.9 1763.3 7.5 3.8 65.8 1.0 2.7 84.9 0.0 0.0 0.2 0.1 0.5 7.2 0.2 15.2 0.7 0.5 39.3 79.7 19.7 7.3 3.4 7.6 4.6 28.8 30.3 10.5 2.2 0.0 1.6 37.6 ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Group enriched" "Detected in many" 4 "Microglial cells: 912.5;Oligodendrocytes: 698.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 35.8;HUVEC TERT2: 45.9;SK-MEL-30: 62.3;TIME: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" 8.8 1.4 5.8 1.8 13.3 3.1 6.4 14.3 8.4 1.9 10.4 2.0 0.7 5.9 0.5 1.9 2.7 2.5 4.4 6.9 9.0 8.7 2.0 5.2 2.0 15.2 10.6 2.3 0.9 4.4 2.1 3.1 17.2 1.1 2.4 3.9 1.1 1.6 1.6 0.8 1.4 4.5 13.3 1.4 1.5 0.3 11.3 0.9 13.3 6.5 0.7 2.6 1.6 21.0 0.2 0.0 35.8 0.0 0.6 0.0 0.0 0.0 4.2 0.6 0.4 11.9 0.1 0.6 2.4 0.3 2.3 0.1 0.0 0.4 0.3 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.6 0.0 0.0 1.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 2.9 0.0 1.8 1.7 0.0 0.0 0.0 2.7 8.8 0.0 0.0 62.3 8.3 0.0 0.2 20.6 0.3 2.8 0.1 3.3 0.0 0.0 0.0 0.0 8.4 5.5 0.0 6.3 2.8 0.0 2.2 0.0 2.6 0.3 0.5 2.3 3.8 1.3 1.4 3.9 0.3 4.3 0.0 0.0 1.9 5.8 13.3 14.3 8.4 6.9 9.0 15.2 10.6 17.2 13.3 11.3 21.0 59.8 3.2 1.5 174.3 5.6 0.3 0.2 0.0 0.6 3.2 0.6 1.0 1.2 0.0 0.0 3.7 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.1 4.5 23.2 0.0 0.4 107.0 0.0 0.1 2.5 3.6 0.1 0.0 0.8 66.0 0.8 1.1 0.0 101.4 0.5 0.0 9.8 0.7 0.8 0.0 3.7 5.4 912.5 3.0 12.3 1.0 23.1 698.3 0.2 3.4 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.3 0.2 0.7 0.1 0.4 0.1 2.0 6.9 0.3 0.1 ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lung: 5.9" "Cell type enriched" "Detected in some" 5 "Microglial cells: 137.7" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "HMC-1: 208.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" 0.7 0.3 5.8 0.4 4.1 1.8 5.2 3.2 3.6 0.3 2.4 0.6 0.3 0.4 4.6 0.5 0.3 0.5 3.4 2.9 3.3 0.8 1.0 5.9 0.2 5.4 10.5 0.4 0.2 0.0 0.3 1.1 4.6 1.5 0.4 0.4 0.6 0.2 0.2 1.0 0.4 0.3 3.6 0.6 0.3 0.3 8.0 0.3 0.4 0.8 0.4 0.2 0.4 4.3 0.2 0.2 0.1 1.7 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.6 0.6 0.0 0.1 0.3 0.3 0.5 0.1 0.0 0.0 0.4 0.2 25.9 0.4 0.5 0.0 0.0 208.0 0.1 0.0 0.2 0.1 1.8 0.0 0.3 4.6 0.4 2.5 1.9 1.1 0.4 2.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 9.3 0.2 1.1 0.0 3.6 0.1 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.1 1.7 0.5 0.5 0.5 0.1 0.2 0.1 0.3 0.3 0.2 0.3 0.3 0.4 1.0 0.7 0.3 0.2 0.8 0.2 5.8 4.1 3.2 3.6 2.9 3.3 5.4 10.5 4.6 3.6 8.0 4.3 0.6 0.0 0.0 2.6 0.1 0.6 0.1 0.2 0.0 0.0 10.0 3.9 0.8 0.0 0.2 0.0 0.0 0.0 5.5 1.2 0.0 0.0 0.5 0.1 0.0 10.9 0.0 25.5 3.0 0.0 0.0 0.3 0.0 0.8 10.2 2.8 26.7 0.0 0.1 0.0 4.4 0.0 0.0 0.9 0.0 0.6 0.0 0.2 8.8 137.7 0.2 0.0 8.2 1.5 1.1 0.1 0.1 0.0 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.8 0.3 0.0 0.0 0.0 2.4 0.1 0.0 0.1 STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.7" "Cell type enhanced" "Detected in all" "Early spermatids: 520.2;Hepatocytes: 660.0;Intestinal goblet cells: 717.9;Late spermatids: 2055.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 617.7;OE19: 1316.9;SK-BR-3: 427.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026661 Uncertain Supported Cytosol NA NA 13000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA026661: AB_1857538" "prognostic favorable (6.92e-4)" "unprognostic (2.07e-1)" "unprognostic (8.03e-2)" "unprognostic (1.74e-3)" "unprognostic (3.71e-2)" "unprognostic (1.37e-2)" "unprognostic (2.50e-2)" "unprognostic (2.16e-1)" "unprognostic (4.16e-1)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (4.24e-3)" "unprognostic (8.42e-2)" "unprognostic (2.29e-1)" "unprognostic (2.12e-2)" "unprognostic (1.04e-1)" 11.8 178.2 35.1 17.7 37.6 10.3 62.1 39.2 41.8 71.9 40.9 180.6 48.5 27.3 102.9 52.0 26.4 59.5 72.5 33.9 34.1 50.1 709.7 37.7 14.5 38.0 33.0 31.0 212.6 73.2 36.2 40.2 38.2 86.2 188.1 18.7 94.5 30.9 66.7 62.6 66.0 26.7 29.9 20.2 266.9 184.3 34.4 15.6 47.9 157.9 21.8 24.5 41.1 35.7 51.2 15.3 7.7 28.7 9.8 9.6 98.3 5.6 26.2 17.3 17.3 209.8 36.7 4.4 16.7 19.2 42.3 31.8 23.4 46.8 20.2 28.3 9.0 5.9 11.1 217.6 35.2 1.6 10.0 6.6 127.0 19.1 26.7 47.2 17.8 10.0 12.1 21.5 3.9 617.7 4.8 11.1 3.4 1316.9 20.1 4.5 13.3 3.4 23.5 61.4 13.0 10.1 8.6 427.4 73.3 32.8 235.5 6.3 13.6 17.0 11.4 6.0 10.1 22.2 19.8 7.5 4.3 5.6 6.5 12.9 2.6 16.0 1.6 1.1 1.2 4.2 1.5 1.7 1.2 2.4 1.6 1.6 21.7 7.5 0.6 2.6 2.1 1.1 35.1 37.6 39.2 41.8 33.9 34.1 38.0 33.0 38.2 29.9 34.4 35.7 10.6 35.3 74.1 8.1 18.1 31.5 76.3 41.0 25.0 10.5 163.3 125.3 45.3 270.2 76.4 55.2 22.9 212.8 17.1 362.8 123.3 70.7 520.2 26.5 6.8 18.5 302.2 22.9 11.6 94.3 93.1 21.1 372.1 25.3 25.4 10.1 30.0 660.0 26.4 33.7 13.9 717.9 85.5 26.0 34.4 2055.8 26.1 12.3 16.0 5.6 7.7 64.4 7.2 8.0 11.8 93.9 398.9 25.2 13.3 150.9 73.5 58.0 34.5 16.6 6.6 11.3 19.6 101.2 22.7 30.2 55.0 352.2 15.6 7.7 440.7 132.7 STARD8 "ARHGAP38, KIAA0189" ENSG00000130052 "StAR related lipid transfer domain containing 8" Q92502 X 68647666-68725842 "Metabolic proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.9;Endothelial cells: 26.5;Hepatic stellate cells: 18.5;Kupffer cells: 13.7;Langerhans cells: 14.9;Macrophages: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "classical monocyte: 1.6;intermediate monocyte: 3.2;myeloid DC: 3.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 18 "dendritic cells: 3.4;monocytes: 4.7" "Cell line enhanced" "Detected in many" "HEL: 16.0;K-562: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA060788 Uncertain NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA060788: AB_2684365" "unprognostic (2.00e-1)" "unprognostic (8.98e-2)" "unprognostic (1.56e-3)" "unprognostic (4.94e-3)" "unprognostic (1.73e-1)" "unprognostic (2.61e-2)" "unprognostic (2.77e-2)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (5.09e-3)" "unprognostic (9.72e-2)" "unprognostic (9.58e-2)" "unprognostic (5.19e-3)" "unprognostic (4.89e-3)" "unprognostic (9.46e-2)" "unprognostic (4.88e-2)" "unprognostic (1.07e-2)" 13.4 4.4 8.1 6.0 6.9 3.4 10.3 6.4 6.8 6.3 5.7 4.0 1.4 7.1 4.7 3.4 8.9 5.2 12.5 6.3 6.3 14.7 6.5 20.7 4.1 13.5 7.5 3.3 5.1 2.6 8.9 8.8 8.1 9.2 1.5 0.6 2.7 8.5 6.8 2.8 4.3 6.1 8.2 11.1 4.2 0.8 8.4 1.6 10.3 6.5 1.9 6.6 4.5 6.6 0.0 1.8 2.8 1.4 0.0 0.0 2.1 3.8 7.9 2.1 1.6 0.0 0.4 0.0 9.6 1.6 0.2 0.0 0.8 0.0 3.5 0.0 0.5 16.0 1.4 0.2 0.3 0.0 0.0 1.3 0.0 5.4 0.0 6.1 9.9 0.0 20.4 0.0 5.3 0.8 0.0 9.5 1.6 0.0 0.3 0.0 10.1 5.4 9.5 0.0 0.0 0.7 0.1 0.9 0.3 5.6 1.3 2.2 7.0 9.6 4.0 3.1 3.7 0.0 0.0 0.0 7.2 6.6 5.7 0.0 1.6 0.0 0.0 3.2 0.0 0.2 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.0 4.7 0.1 0.0 1.8 8.1 6.9 6.4 6.8 6.3 6.3 13.5 7.5 8.1 8.2 8.4 6.6 27.9 0.0 6.0 0.0 0.3 2.2 0.0 0.0 0.0 0.0 0.2 0.3 8.5 0.0 1.8 0.0 0.0 0.3 0.1 0.0 1.9 0.0 0.1 1.2 1.6 26.5 0.0 2.1 0.3 0.0 0.2 3.0 0.5 1.1 7.0 0.3 18.5 6.5 3.6 0.0 0.8 0.0 0.0 13.7 14.9 0.0 0.3 13.9 0.0 9.4 2.4 0.3 0.0 0.5 0.5 0.8 0.0 0.0 0.9 0.1 0.0 2.4 2.2 0.4 0.0 2.8 3.5 0.1 0.2 0.2 1.4 0.1 0.6 0.2 0.0 0.1 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 STEAP1B ENSG00000105889 "STEAP family member 1B" Q6NZ63 7 22419444-22727613 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;choroid plexus: 4.5" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 129.9" "Cancer enhanced" "Detected in many" "melanoma: 5.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 67 "memory B-cell: 8.4;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 84 "B-cells: 8.4" "Group enriched" "Detected in many" 5 "hTEC/SVTERT24-B: 80.7;HUVEC TERT2: 105.0;K-562: 45.4;WM-115: 112.0" NA NA "Cluster 37: B-cells - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (7.35e-2)" "unprognostic (2.42e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-3)" "unprognostic (3.96e-2)" "unprognostic (2.18e-1)" "unprognostic (2.31e-5)" "unprognostic (2.29e-3)" "unprognostic (4.96e-2)" "unprognostic (7.37e-3)" "unprognostic (7.38e-2)" "unprognostic (1.27e-2)" "unprognostic (2.85e-10)" "unprognostic (1.06e-4)" "unprognostic (3.46e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-3)" 1.0 0.5 1.6 1.1 3.3 0.1 0.8 2.1 2.7 1.2 4.5 0.7 0.1 0.2 0.4 0.6 0.3 0.7 0.5 1.9 2.3 0.2 0.2 0.4 1.6 3.4 2.4 0.1 0.3 0.1 0.3 1.2 3.7 0.5 0.5 0.3 0.4 0.6 1.2 0.4 0.3 0.6 1.4 1.8 0.4 2.3 2.6 1.1 0.2 0.6 1.6 0.8 1.7 6.9 13.5 0.1 8.3 0.0 6.3 9.2 0.0 9.7 1.1 0.2 0.3 0.0 0.3 1.7 2.7 16.9 2.8 0.0 12.3 0.1 0.4 0.5 1.1 0.0 0.3 0.0 0.9 0.0 0.1 10.6 0.0 80.7 0.2 9.7 105.0 0.4 45.4 4.5 0.0 0.0 0.1 0.0 16.8 0.0 0.1 1.7 0.0 5.4 0.1 0.0 0.0 0.2 0.3 0.0 6.4 1.0 0.1 0.0 12.3 1.0 0.4 11.5 0.1 1.1 9.8 12.2 17.7 0.0 112.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 3.3 2.1 2.7 1.9 2.3 3.4 2.4 3.7 1.4 2.6 6.9 2.4 0.0 0.0 1.6 4.6 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 5.1 0.4 0.1 1.3 0.0 0.0 9.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.1 0.5 11.8 2.1 0.0 0.0 0.3 0.5 1.5 0.0 1.3 3.6 5.6 11.9 0.0 0.0 7.5 129.9 0.4 0.0 0.4 0.8 0.1 0.0 0.0 0.1 0.2 0.0 0.0 2.7 7.4 11.6 0.1 0.1 0.1 0.0 5.1 0.2 0.1 STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 25.3;Cardiomyocytes: 27.7;dendritic cells: 17.0;Hofbauer cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 64.4;EFO-21: 83.8;HDLM-2: 200.5;THP-1: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038116, HPA038534" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA038116: AB_2675841, HPA038534: AB_2676067" "unprognostic (1.45e-1)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-2)" "unprognostic (1.71e-2)" "unprognostic (7.66e-2)" "unprognostic (2.77e-2)" "unprognostic (6.30e-2)" "unprognostic (1.01e-1)" "unprognostic (5.69e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.59e-8)" "unprognostic (9.18e-3)" "unprognostic (4.14e-2)" "unprognostic (4.45e-2)" "unprognostic (1.34e-1)" 38.9 9.3 4.6 18.4 5.0 16.9 26.2 4.4 5.4 32.6 12.8 16.6 6.7 25.0 6.8 21.5 36.2 11.9 35.7 4.3 4.9 17.3 5.5 48.1 15.0 5.5 4.9 21.9 5.4 3.3 11.8 12.9 5.1 20.7 11.6 0.3 24.5 15.5 7.5 15.5 19.0 18.7 5.3 37.8 11.6 3.1 6.0 12.4 20.2 8.5 27.1 21.7 28.4 4.8 2.9 0.7 0.2 0.0 4.0 12.0 0.2 15.3 64.4 7.6 24.4 0.0 18.8 0.0 83.8 49.0 1.9 10.8 0.4 22.9 4.8 200.5 3.3 13.5 6.6 0.8 7.5 4.1 0.8 16.2 1.2 4.6 5.7 12.8 27.8 1.4 3.9 58.3 33.6 0.0 2.2 24.1 0.1 0.8 4.7 0.7 6.1 18.0 9.4 7.0 5.8 0.0 6.5 5.3 16.0 0.6 0.7 73.3 17.2 1.9 1.3 6.8 5.6 0.0 20.0 0.1 0.3 56.2 11.3 16.6 60.9 0.1 56.9 40.0 29.3 0.6 57.4 47.8 55.6 0.3 40.3 35.0 5.0 90.6 17.5 19.2 65.3 60.6 4.6 5.0 4.4 5.4 4.3 4.9 5.5 4.9 5.1 5.3 6.0 4.8 25.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.0 0.0 0.0 0.0 0.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.6 8.4 0.0 0.0 0.0 0.0 0.0 0.0 67.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.8 5.8 0.0 0.0 0.0 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 15.2 24.9 17.6 11.8 17.5 15.0 16.2 16.3 20.5 14.0 19.5 20.0 17.3 13.8 20.8 22.8 18.1 13.0 19.0 16.5 16.8 26.5 43.2 14.3 17.6 17.9 17.5 14.8 30.9 22.7 19.8 9.2 16.9 20.3 13.5 7.9 20.0 10.9 14.4 17.3 17.8 9.9 17.4 21.2 24.2 27.7 18.6 20.5 19.3 8.2 14.5 17.8 14.8 16.5 14.1 18.8 15.7 13.2 40.0 40.0 17.9 17.8 23.6 14.3 14.7 21.2 31.0 8.3 24.4 32.0 23.4 14.5 18.5 30.0 7.8 20.0 19.8 17.7 15.4 19.1 34.9 17.6 20.1 40.1 48.1 20.8 57.4 29.8 17.9 18.7 23.1 21.5 26.8 27.1 19.4 38.0 14.5 25.7 10.3 18.1 17.5 24.9 32.2 16.1 12.3 14.6 5.8 25.5 39.0 11.2 27.4 36.4 13.7 20.6 14.0 16.4 17.4 25.9 12.1 19.5 22.9 18.4 18.3 1.6 7.0 5.3 4.9 3.8 5.5 7.2 6.0 9.2 6.8 6.0 6.1 7.9 4.1 14.5 3.1 5.8 7.3 8.7 17.6 17.5 16.3 20.5 16.5 16.8 17.9 17.5 16.9 17.4 18.6 16.5 11.8 6.4 5.6 3.6 22.4 9.8 18.1 32.6 24.5 7.9 31.8 31.8 9.5 24.3 19.7 7.3 16.7 24.0 23.6 27.6 68.4 40.3 87.2 21.4 13.3 14.0 25.8 36.0 2.2 58.5 25.0 15.8 17.3 12.9 8.2 17.9 12.5 43.7 28.4 13.5 2.7 38.7 16.2 27.1 17.6 70.3 15.2 17.8 21.4 0.0 38.4 22.1 44.3 4.0 6.8 33.3 44.3 13.5 27.6 18.6 58.9 80.2 19.6 19.1 0.0 11.9 19.2 43.1 9.6 28.2 11.2 12.9 22.1 33.6 34.2 20.8 STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 70.0;epididymis: 56.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 55.2;dendritic cells: 42.7;NK-cells: 53.5;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 140.1;U-937: 144.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 360000 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: AB_2684163" "unprognostic (6.53e-2)" "unprognostic (7.83e-2)" "unprognostic (1.77e-1)" "unprognostic (1.02e-3)" "unprognostic (4.42e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (4.76e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" 6.0 2.5 1.0 15.2 2.7 70.0 6.0 1.7 1.3 6.8 2.5 11.5 9.6 46.6 56.3 13.1 7.4 5.6 1.4 0.7 1.5 3.5 5.2 7.2 26.2 0.8 0.8 2.1 3.7 23.5 5.0 25.2 0.7 20.0 11.6 0.2 7.3 35.8 0.9 7.8 6.9 38.1 0.6 13.2 12.2 2.2 3.8 41.3 3.7 1.2 23.5 11.8 7.4 0.7 32.9 11.3 1.3 0.0 5.2 4.9 72.0 1.0 4.0 0.5 0.6 30.1 29.0 44.6 19.4 7.3 22.1 36.5 80.8 51.1 0.0 39.1 66.6 64.6 25.9 28.4 4.7 135.3 5.1 6.9 30.0 0.1 33.7 15.1 14.2 60.0 29.2 40.4 12.2 29.0 140.1 124.9 64.4 22.0 4.3 99.9 39.7 57.9 32.6 51.8 26.6 29.6 19.2 17.0 0.9 54.9 22.0 35.4 0.3 12.8 13.7 39.0 47.9 31.0 52.0 49.8 11.7 144.8 6.5 59.1 9.5 31.6 22.8 12.4 22.4 14.5 15.2 19.6 11.3 12.6 19.7 20.6 18.2 41.0 22.7 4.2 7.2 20.4 1.0 2.7 1.7 1.3 0.7 1.5 0.8 0.8 0.7 0.6 3.8 0.7 0.9 22.4 15.6 0.0 24.7 0.0 36.4 0.0 6.8 0.0 5.9 10.9 1.3 5.7 8.1 11.0 0.0 55.2 42.7 6.5 3.9 4.5 0.6 7.4 1.8 1.7 1.2 12.8 2.0 7.1 34.7 9.6 15.3 17.9 11.4 0.5 1.4 4.4 11.8 0.0 1.4 4.8 0.0 8.8 0.0 0.4 3.4 17.3 0.0 2.8 13.5 0.0 53.5 0.0 0.2 10.9 4.0 2.2 14.5 33.6 1.9 1.5 6.6 0.0 6.6 6.7 3.6 1.8 2.5 16.1 0.0 59.1 27.4 0.6 6.5 18.2 STK32A "MGC22688, YANK1" ENSG00000169302 "Serine/threonine kinase 32A" Q8WU08 5 147234963-147387855 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.2;brain: 24.4" "Cell type enriched" "Detected in many" 19 "Oligodendrocyte precursor cells: 306.6" "Group enriched" "Detected in many" 5 "glioma: 4.3;melanoma: 11.9;thyroid cancer: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 13.6;SK-MEL-30: 48.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040236 Approved Centrosome NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Centrosome "HPA040236: AB_10795416" "unprognostic (1.90e-1)" "unprognostic (4.71e-4)" "unprognostic (5.32e-2)" "unprognostic (3.49e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (2.96e-3)" "unprognostic (4.85e-2)" "unprognostic (2.36e-2)" "unprognostic (3.87e-1)" "unprognostic (8.38e-2)" "unprognostic (2.50e-3)" "unprognostic (5.53e-5)" "unprognostic (2.48e-1)" "unprognostic (3.20e-2)" "unprognostic (3.67e-3)" 1.3 11.2 5.9 0.6 9.5 0.0 1.2 13.2 3.1 1.0 1.0 2.3 0.5 0.5 2.6 0.3 0.8 1.5 1.0 3.5 14.4 3.4 0.1 1.2 0.0 11.7 24.4 2.5 2.6 0.1 8.1 0.1 17.0 1.0 0.3 2.6 0.9 0.8 0.2 3.7 0.7 0.4 10.4 0.3 1.2 1.0 14.0 0.1 8.7 0.5 0.0 1.7 1.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.5 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.2 4.4 13.6 1.2 0.5 0.0 0.0 48.6 0.2 0.0 0.0 0.1 0.0 0.5 0.7 0.4 1.0 0.2 0.0 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 9.5 13.2 3.1 3.5 14.4 11.7 24.4 17.0 10.4 14.0 10.1 0.2 0.0 2.6 8.5 0.0 1.5 0.2 1.4 0.0 1.8 1.3 0.5 0.5 0.0 1.0 1.8 0.0 0.0 0.0 0.1 1.9 1.8 6.9 0.2 0.5 0.1 0.0 0.0 4.6 2.7 0.0 2.7 0.0 0.7 0.0 4.2 0.0 0.0 0.1 0.0 5.2 0.0 2.0 0.0 1.0 10.5 0.9 0.2 16.0 0.0 0.0 4.0 0.0 306.6 0.7 5.5 0.0 4.1 0.0 0.3 0.0 4.1 0.2 1.0 0.0 5.4 0.5 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.0 0.6 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 STXBP2 "Hunc18b, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636881-7647873 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 194.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 262.5;Macrophages: 249.1;monocytes: 368.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 248.6;classical monocyte: 471.0;eosinophil: 295.6;intermediate monocyte: 604.8;myeloid DC: 239.7;neutrophil: 356.2;non-classical monocyte: 893.3" "Group enriched" "Detected in all" 6 "dendritic cells: 239.7;granulocytes: 356.2;monocytes: 893.3" "Cell line enhanced" "Detected in many" "HMC-1: 244.8;U-937: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" 24.2 22.8 5.2 65.9 6.3 194.2 24.3 4.8 10.9 22.2 9.3 52.5 67.4 8.4 33.2 73.1 27.7 28.4 7.5 5.1 6.2 62.4 49.0 89.6 51.0 8.3 6.6 5.3 86.7 36.1 29.4 36.3 7.9 52.1 37.0 4.2 79.4 22.8 2.9 52.3 63.9 14.6 6.7 162.2 71.9 74.9 8.8 85.3 52.0 3.0 34.6 34.6 34.8 9.3 113.0 39.1 0.9 0.5 0.0 0.9 75.6 14.2 1.5 2.7 7.4 92.5 69.6 29.6 55.4 11.3 49.5 75.5 4.1 67.5 2.7 124.1 46.9 127.8 49.7 55.8 63.6 83.2 244.8 4.4 67.4 13.4 38.0 0.3 58.5 74.7 81.4 98.5 0.0 70.9 41.2 193.2 28.7 72.7 68.0 41.8 0.3 114.7 55.0 128.1 11.5 0.6 34.0 49.6 2.2 35.6 61.9 212.7 61.7 0.4 21.8 1.5 0.8 108.4 58.6 38.8 1.2 224.8 2.7 248.6 471.0 295.6 69.9 604.8 56.7 47.3 52.7 63.8 239.7 52.2 36.6 44.3 356.2 74.7 893.3 91.5 78.9 306.9 5.2 6.3 4.8 10.9 5.1 6.2 8.3 6.6 7.9 6.7 8.8 9.3 2.1 0.0 7.7 0.7 44.1 23.6 48.2 105.1 18.8 6.0 38.0 22.9 0.9 31.5 68.5 35.0 2.1 97.7 56.2 181.4 33.2 100.3 99.9 32.5 5.4 6.7 59.8 38.3 0.6 118.8 123.2 5.7 150.3 47.6 71.8 34.6 16.4 19.6 168.4 0.0 0.4 108.2 105.8 262.5 46.6 233.5 1.8 249.1 14.2 1.0 368.2 0.9 72.1 0.0 0.0 132.8 152.6 1.9 54.7 49.1 171.7 75.9 42.5 4.0 6.6 1.0 8.6 45.7 20.2 35.3 21.3 153.0 47.7 6.0 79.3 68.7 SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 39.9" "Cell type enhanced" "Detected in some" "Distal tubular cells: 19.6;Hofbauer cells: 22.0;Kupffer cells: 32.0;Macrophages: 11.8;Proximal tubular cells: 46.3;Smooth muscle cells: 11.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEL: 53.3;NB-4: 31.0;U-937: 52.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022745 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" 3.5 0.8 0.0 1.3 0.1 8.1 1.0 0.0 0.2 0.2 0.0 0.5 1.2 0.1 0.1 0.2 0.1 0.5 0.7 0.0 0.2 39.9 5.2 2.6 1.9 0.2 0.2 0.1 0.0 3.4 0.0 0.2 0.3 0.1 0.8 0.0 0.6 0.1 0.0 1.0 1.0 0.7 0.1 7.0 7.8 0.1 0.4 0.9 9.3 0.1 0.6 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.0 0.0 8.7 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.2 0.2 0.3 0.1 0.4 0.2 8.4 0.0 1.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.5 1.5 0.1 3.7 0.0 0.1 1.4 0.0 19.6 0.0 0.5 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 4.3 22.0 0.0 0.0 0.2 8.2 32.0 8.1 0.4 0.0 11.8 0.0 8.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 46.3 1.5 0.0 0.0 0.1 11.2 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.1 SUMO3 "SMT3A, SMT3H1" ENSG00000184900 "Small ubiquitin like modifier 3" P55854 21 44805617-44818779 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012180, HPA042123, HPA048064" Supported Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nuclear bodies" "CAB012180: AB_304041, HPA042123: AB_2677860, HPA048064: AB_2680244" "unprognostic (2.77e-2)" "unprognostic (2.52e-1)" "unprognostic (5.79e-2)" "prognostic unfavorable (7.88e-5)" "unprognostic (1.96e-1)" "unprognostic (1.21e-1)" "unprognostic (6.81e-2)" "unprognostic (7.13e-2)" "unprognostic (1.43e-1)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (7.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.00e-2)" "unprognostic (1.62e-1)" "unprognostic (7.50e-2)" "unprognostic (1.80e-2)" 68.6 58.1 58.5 56.7 64.6 118.8 63.6 50.6 75.5 55.5 55.9 55.2 55.1 52.9 50.3 57.2 52.1 44.6 74.3 64.4 71.8 64.0 59.3 61.7 68.8 53.3 59.0 57.6 49.4 44.7 38.3 49.1 58.3 46.2 45.8 72.0 66.5 47.4 106.6 51.0 58.0 39.8 54.5 61.6 56.3 28.8 68.5 63.7 54.8 73.9 57.5 50.0 53.6 50.9 226.4 88.8 131.7 80.2 105.1 147.9 86.5 152.0 177.2 211.5 173.6 133.6 137.2 78.4 234.6 165.4 122.4 53.0 96.8 123.0 166.3 110.0 106.3 322.7 78.8 123.1 113.3 184.5 172.1 126.0 139.5 123.9 89.9 87.8 109.8 164.6 188.7 215.2 173.8 293.1 220.0 127.7 254.4 223.1 174.9 239.0 8.0 217.1 120.2 111.9 98.8 153.4 136.5 196.2 126.3 48.1 190.6 218.6 172.4 99.1 151.4 151.6 172.8 155.4 234.8 198.7 77.9 265.2 138.6 2.8 123.1 52.0 78.9 130.0 79.7 84.6 74.9 76.5 133.3 77.7 88.7 81.0 14.0 70.6 122.3 162.8 91.2 157.8 58.5 64.6 50.6 75.5 64.4 71.8 53.3 59.0 58.3 54.5 68.5 50.9 83.4 64.1 50.4 5.5 76.5 96.0 121.7 127.9 74.6 72.2 99.4 88.5 59.5 67.2 66.5 95.6 20.9 122.9 98.1 95.6 166.3 121.7 63.1 36.4 51.7 101.4 59.2 113.8 14.3 112.4 107.8 76.7 52.0 37.9 29.8 63.8 92.8 116.6 200.5 62.2 13.3 91.5 81.4 143.4 172.3 114.2 72.1 137.9 97.8 10.3 280.0 132.4 111.2 3.5 6.5 148.7 112.6 72.6 58.2 150.7 129.2 130.2 33.0 60.5 59.2 43.8 68.7 90.7 77.5 82.7 77.9 136.3 78.2 43.2 99.9 145.1 SURF4 "ERV29, FLJ22993, MGC102753" ENSG00000148248 "Surfeit 4" O15260 9 133361450-133376166 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064613 Approved Supported "Nuclear membrane,Endoplasmic reticulum,Golgi apparatus,Cytosol" NA Yes 65000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Endoplasmic reticulum, Golgi apparatus" Cytosol "HPA064613: AB_2685299" "prognostic unfavorable (5.85e-4)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.04e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (1.47e-5)" "prognostic unfavorable (8.11e-4)" "unprognostic (1.10e-3)" "unprognostic (3.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.30e-3)" "unprognostic (1.23e-1)" "unprognostic (9.76e-3)" "unprognostic (7.58e-3)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (4.29e-3)" 97.0 106.4 20.3 38.8 22.5 66.5 76.5 22.1 23.4 70.5 27.9 72.1 79.2 78.5 40.6 77.6 71.1 39.0 74.1 21.5 22.3 67.1 223.8 84.2 29.6 23.6 22.2 61.0 150.4 35.4 88.6 55.4 22.2 69.2 37.9 14.0 86.4 39.5 60.1 63.2 82.2 43.4 22.9 59.6 88.5 49.4 25.8 27.8 68.2 23.3 31.4 62.7 59.4 25.9 59.8 96.4 65.3 90.3 134.8 140.2 127.4 184.1 178.4 127.0 124.7 145.9 84.8 41.1 70.6 254.2 122.9 152.7 75.7 94.4 97.0 86.5 46.3 72.1 87.1 156.5 156.2 124.8 94.1 150.4 85.8 109.3 120.2 101.6 118.6 62.9 89.0 109.8 164.5 131.8 60.1 115.4 72.7 162.8 96.2 41.2 89.9 156.5 100.4 56.3 53.8 65.5 136.4 100.4 95.2 61.5 106.6 75.8 127.5 179.4 64.5 137.3 119.6 56.1 86.4 46.4 166.7 66.6 137.5 43.9 40.8 36.2 51.9 32.8 56.9 15.1 36.3 48.4 32.9 12.1 22.0 34.6 28.4 29.4 31.7 38.9 46.9 68.8 20.3 22.5 22.1 23.4 21.5 22.3 23.6 22.2 22.2 22.9 25.8 25.9 53.5 44.8 48.1 18.9 43.0 60.8 65.8 72.5 46.1 21.9 55.5 43.2 42.6 31.5 47.5 35.0 39.6 167.9 80.4 106.9 19.6 95.7 38.6 28.6 72.8 54.8 75.2 31.1 23.2 118.1 254.4 84.8 78.5 67.7 24.7 49.5 47.5 207.3 85.9 33.7 15.6 107.9 30.5 52.3 50.5 19.7 68.3 50.8 40.9 17.8 53.7 53.3 52.5 22.6 23.8 115.1 65.5 53.0 114.8 106.8 151.3 48.5 23.2 26.9 78.9 51.9 80.6 84.4 47.3 46.1 62.4 325.2 90.5 81.8 81.2 84.2 SUSD3 MGC26847 ENSG00000157303 "Sushi domain containing 3" Q96L08 9 93058688-93085133 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.3;testis: 77.2" "Cell type enhanced" "Detected in many" "B-cells: 32.4;Granulosa cells: 30.8;Hepatocytes: 66.6;Hofbauer cells: 49.4;Proximal tubular cells: 59.4;T-cells: 37.5;Theca cells: 34.7" "Cancer enhanced" "Detected in all" "breast cancer: 50.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 150.7;Karpas-707: 32.6;MCF7: 36.8;NB-4: 78.0;RPMI-8226: 82.5;THP-1: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042310 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 32: Non-specific - Translation" "HPA042310: AB_10796902" "prognostic favorable (5.13e-4)" "unprognostic (5.42e-2)" "unprognostic (3.65e-1)" "unprognostic (8.34e-3)" "unprognostic (9.06e-2)" "unprognostic (2.84e-2)" "unprognostic (2.94e-2)" "unprognostic (7.41e-3)" "unprognostic (5.06e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (3.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.39e-3)" "unprognostic (5.33e-2)" 6.1 1.8 4.5 17.6 3.9 41.3 15.4 4.6 4.3 16.7 4.4 3.8 4.9 19.8 10.0 4.2 35.4 4.2 1.3 4.3 5.6 21.2 27.8 4.1 57.3 6.4 5.7 40.1 1.0 1.3 5.4 2.0 6.5 2.4 2.2 6.4 11.4 3.2 1.2 3.6 18.7 6.1 6.6 36.3 4.5 77.2 5.9 31.8 4.2 0.6 30.5 4.4 6.1 8.0 7.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 1.5 0.6 0.3 3.4 1.3 150.7 0.6 0.6 0.1 0.3 2.4 0.1 0.0 13.4 0.1 20.7 0.1 2.4 9.5 0.1 4.6 9.9 0.7 0.0 0.0 0.0 0.0 0.0 6.2 32.6 0.0 36.8 0.2 78.0 1.8 1.1 4.6 6.5 0.0 82.5 0.0 0.0 0.2 0.2 0.1 1.1 0.0 1.7 19.4 34.6 0.5 0.0 0.0 0.0 0.0 6.6 3.8 9.7 0.0 0.0 0.2 0.6 16.7 79.1 24.0 15.5 27.4 88.7 124.8 43.4 41.1 70.1 214.8 87.7 5.8 11.2 3.0 3.6 182.9 68.3 4.5 3.9 4.6 4.3 4.3 5.6 6.4 5.7 6.5 6.6 5.9 8.0 2.6 0.0 6.7 0.0 32.4 0.6 0.2 0.3 0.0 0.5 24.2 11.0 0.8 17.2 0.2 0.0 4.2 1.0 2.4 0.4 9.8 0.7 3.0 0.4 2.9 3.4 0.0 2.5 0.1 0.2 2.1 9.0 1.1 0.3 3.8 30.8 1.4 66.6 49.4 0.0 0.1 0.4 8.2 10.5 9.2 11.2 5.6 29.1 1.8 17.8 8.3 1.7 2.1 0.5 0.1 0.6 0.1 5.3 17.9 1.4 0.2 59.4 0.7 9.2 0.0 0.1 1.6 3.4 3.9 0.1 0.3 1.4 37.5 34.7 0.7 0.2 SYN2 "SYNII, SYNIIa, SYNIIb" ENSG00000157152 "Synapsin II" Q92777 3 12004388-12192032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Schizophrenia "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 96.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 338.3;Inhibitory neurons: 543.3;Oligodendrocyte precursor cells: 128.2" "Cancer enhanced" "Detected in many" "glioma: 4.5" "Group enriched" "Detected in many" 5 "amygdala: 67.0;basal ganglia: 77.7;cerebral cortex: 96.8;hippocampal formation: 92.9;white matter: 44.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HMC-1: 4.5;NTERA-2: 3.3;SCLC-21H: 2.7;SH-SY5Y: 11.1;SuSa: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037012, CAB079005" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "CAB079005: , HPA037012: AB_2675431" "unprognostic (1.62e-3)" "unprognostic (1.60e-2)" "unprognostic (7.54e-2)" "unprognostic (9.87e-3)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (6.32e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (9.77e-2)" "unprognostic (4.89e-4)" "unprognostic (9.94e-2)" "unprognostic (7.35e-2)" "unprognostic (1.78e-2)" 7.0 3.1 67.0 0.4 77.7 0.1 7.1 3.8 96.8 1.4 0.0 2.3 0.4 2.0 1.0 0.3 1.2 0.4 1.0 92.9 2.9 1.5 0.0 1.1 0.0 13.4 0.0 1.5 0.5 4.1 3.4 2.8 10.8 0.5 0.5 7.8 2.4 0.2 0.9 2.5 1.6 1.8 0.0 0.6 1.8 3.6 15.3 0.1 0.2 0.4 0.0 0.3 1.3 44.9 0.0 0.2 0.0 0.0 1.8 0.5 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.2 1.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.2 0.0 0.0 0.0 0.0 0.2 2.7 11.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 67.0 77.7 3.8 96.8 92.9 2.9 13.4 0.0 10.8 0.0 15.3 44.9 43.4 0.0 0.0 7.8 0.0 0.0 0.4 0.0 0.6 13.9 0.4 2.4 1.4 0.0 0.0 0.0 6.2 1.7 0.1 0.0 0.0 0.0 0.6 0.2 0.1 4.5 0.0 0.0 338.3 0.0 0.4 0.9 0.0 0.3 0.0 0.2 0.7 0.0 0.6 13.5 543.3 0.0 0.0 1.8 0.0 1.8 0.0 0.3 0.0 4.7 0.1 2.5 0.0 128.2 8.3 0.3 0.0 0.0 0.0 0.3 0.0 2.7 0.0 3.7 0.0 0.7 0.7 4.9 6.9 0.0 0.0 0.8 0.1 0.1 0.0 0.2 SYNGR2 ENSG00000108639 "Synaptogyrin 2" O43760 17 78168581-78173527 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Exocrine glandular cells: 434.8;monocytes: 836.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 672.3;OE19: 547.9;SK-BR-3: 630.6;T-47d: 502.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014742 Approved Approved "Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "HPA014742: AB_2669079" "unprognostic (2.19e-2)" "unprognostic (1.05e-3)" "unprognostic (2.84e-1)" "unprognostic (6.77e-3)" "unprognostic (9.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-3)" "unprognostic (4.98e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-2)" "unprognostic (9.44e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (4.74e-2)" "unprognostic (5.21e-2)" "unprognostic (3.51e-2)" "unprognostic (1.78e-2)" 92.9 59.7 50.9 99.4 74.0 112.9 105.5 75.1 63.5 59.2 53.5 118.0 86.4 56.7 22.6 133.8 75.5 70.7 150.1 51.5 61.2 113.0 101.0 158.1 143.9 88.1 70.7 45.3 188.9 52.9 91.2 61.7 86.0 130.7 71.1 2.8 184.8 45.6 369.9 161.4 125.4 33.2 67.3 148.1 141.7 31.8 68.0 68.2 68.7 122.6 112.6 92.0 87.9 92.5 172.5 334.5 9.0 73.9 3.2 1.1 52.5 58.6 60.2 55.0 31.4 200.9 173.6 136.9 123.2 33.5 47.8 245.5 39.9 95.0 16.2 97.2 177.2 47.0 46.9 140.8 76.1 77.3 356.5 3.4 105.1 17.5 47.2 77.9 118.7 50.4 193.9 672.3 5.3 337.4 77.3 79.6 24.4 547.9 140.1 44.3 19.2 391.4 166.7 155.5 53.8 60.2 48.6 630.6 60.3 31.7 502.8 122.2 31.7 1.1 54.2 28.1 77.8 280.7 109.7 79.8 39.7 52.8 9.5 694.4 656.1 237.9 173.6 944.7 202.1 970.0 231.0 200.2 907.6 972.1 204.6 168.6 282.5 219.8 1139.9 530.1 314.6 837.0 50.9 74.0 75.1 63.5 51.5 61.2 88.1 70.7 86.0 67.3 68.0 92.5 56.1 128.2 113.4 3.3 226.6 124.1 136.1 170.9 79.1 3.3 126.5 84.1 63.0 68.6 153.2 171.0 6.2 169.7 63.1 125.2 9.8 313.6 3.6 41.2 9.6 83.5 72.6 70.2 2.4 434.8 59.1 27.9 104.5 89.7 103.0 25.3 56.4 46.9 255.5 5.0 1.2 327.6 193.3 137.9 330.6 4.9 22.1 150.3 74.7 16.9 836.7 5.1 24.7 2.5 31.3 286.5 160.9 17.0 159.2 282.4 77.5 36.2 63.4 3.9 39.5 26.0 46.2 13.4 12.3 120.1 163.4 179.5 58.8 11.4 212.8 216.8 SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 594.1;skeletal muscle: 624.7;urinary bladder: 406.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 103.5;Cardiomyocytes: 502.5;Muller glia cells: 127.8;Smooth muscle cells: 98.5" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.8;HeLa: 58.0;WM-115: 124.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB017192: , HPA040066: AB_2676830, HPA044200: AB_2678854, HPA077856: AB_2686861" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-2)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-2)" "unprognostic (6.75e-2)" "unprognostic (3.54e-3)" "unprognostic (2.80e-2)" "unprognostic (7.27e-2)" "unprognostic (5.92e-3)" "unprognostic (3.26e-3)" 37.2 20.3 51.4 26.5 66.0 0.4 56.7 70.1 58.2 11.8 52.5 594.1 27.1 50.8 12.7 169.6 36.5 19.2 144.2 44.4 75.4 6.9 4.8 23.1 4.2 81.7 66.6 14.1 6.3 8.2 23.2 14.0 81.6 150.6 52.0 40.3 25.6 291.3 624.7 17.0 105.7 160.9 71.6 2.9 158.4 5.2 69.3 3.7 11.2 277.1 4.0 406.3 41.0 79.8 6.6 36.8 8.1 21.9 15.9 0.9 0.5 3.7 5.3 2.1 1.3 5.4 4.9 0.0 5.3 5.3 17.7 4.2 5.5 0.1 1.6 0.5 9.0 0.1 58.0 5.4 9.0 0.0 1.0 0.9 0.3 3.7 0.8 6.0 4.3 0.0 0.2 7.4 5.5 3.7 0.7 0.8 7.2 0.7 11.4 0.0 7.5 5.5 2.1 3.6 3.6 4.2 21.9 3.4 13.5 12.7 0.2 3.6 4.8 4.1 0.4 2.9 8.9 0.1 1.0 0.0 0.4 0.0 124.5 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 51.4 66.0 70.1 58.2 44.4 75.4 81.7 66.6 81.6 71.6 69.3 79.8 14.8 0.0 1.7 15.3 0.9 2.3 0.7 0.9 2.8 12.6 32.7 103.5 502.5 0.0 1.2 0.0 16.7 1.5 6.6 2.1 0.0 0.5 9.5 1.3 1.0 24.2 3.0 0.0 15.6 1.3 0.7 20.3 5.1 4.2 0.0 1.1 3.6 1.3 0.3 42.1 9.8 0.9 0.0 0.0 5.1 4.5 1.2 2.0 5.4 12.2 0.6 127.8 1.0 2.5 14.0 0.2 2.3 4.1 5.4 2.0 0.6 0.3 3.1 10.2 32.9 19.6 98.5 7.9 11.5 2.1 3.7 0.4 5.9 0.2 0.7 0.9 TADA2B MGC21874 ENSG00000173011 "Transcriptional adaptor 2B" Q86TJ2 4 7041899-7057952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 40.4;Rod photoreceptor cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035770 Approved Approved "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA035770: AB_10603993" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (6.61e-2)" "unprognostic (2.77e-3)" "unprognostic (1.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (2.99e-1)" "unprognostic (6.03e-2)" "unprognostic (8.91e-3)" "unprognostic (1.72e-1)" "prognostic favorable (7.17e-11)" "unprognostic (5.00e-2)" "unprognostic (1.58e-1)" "unprognostic (2.59e-2)" "prognostic favorable (1.59e-4)" 10.9 16.3 7.7 13.1 8.1 35.4 10.5 9.3 10.4 10.6 8.3 12.7 13.4 11.8 8.1 14.6 12.2 10.2 20.6 11.0 6.5 12.3 15.7 11.7 17.8 8.7 7.0 19.3 30.2 16.7 9.1 10.8 8.6 12.8 10.3 20.2 24.4 13.0 52.0 12.1 13.0 11.6 6.4 15.3 14.6 15.5 8.2 12.0 16.4 42.4 12.6 11.5 9.2 8.3 11.5 17.2 11.8 14.0 12.8 14.5 11.3 16.5 16.9 20.9 12.8 17.0 16.8 15.2 9.6 18.4 27.8 9.2 16.3 8.7 13.4 9.0 12.5 15.5 10.5 12.9 15.6 17.9 24.3 10.5 18.2 13.9 16.1 14.4 9.8 13.9 17.6 23.9 15.8 11.0 21.8 15.3 14.0 15.3 26.4 14.0 24.1 8.0 19.1 15.9 19.2 13.8 14.2 12.6 16.6 9.5 19.0 26.6 15.3 13.2 10.2 16.1 22.9 21.6 19.5 19.7 10.9 9.7 13.7 0.7 1.3 6.9 2.7 1.7 1.9 2.5 1.7 2.6 1.2 1.7 2.3 1.7 4.4 1.5 2.1 1.3 2.0 1.2 7.7 8.1 9.3 10.4 11.0 6.5 8.7 7.0 8.6 6.4 8.2 8.3 7.1 9.6 15.0 7.2 9.0 4.6 2.7 3.3 0.6 27.1 12.4 8.0 12.7 4.3 9.1 7.3 31.3 3.6 14.2 10.6 5.9 4.5 2.9 8.6 9.0 6.4 7.2 2.1 5.0 9.3 2.9 8.0 8.2 8.7 9.5 6.3 4.2 16.7 5.7 40.4 5.2 9.5 4.1 8.8 4.2 4.8 16.8 7.0 7.2 1.9 8.1 10.4 6.2 5.0 3.7 7.9 7.8 12.8 5.1 5.8 8.7 7.6 7.1 38.3 0.0 12.4 5.2 6.1 4.5 3.6 5.8 4.4 10.1 12.5 6.9 5.4 TAGAP "ARHGAP47, FLJ32631, IDDM21" ENSG00000164691 "T cell activation RhoGTPase activating protein" Q8N103 6 159034468-159045152 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "B-cells: 249.5;dendritic cells: 152.3;Macrophages: 91.1;NK-cells: 86.5;Plasma cells: 272.1;T-cells: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.1;HMC-1: 42.5;Karpas-707: 43.8;U-266/84: 20.6;U-698: 39.6;U-937: 33.4" "Low region specificity" "Detected in all" "HPA031000, HPA039982" Uncertain Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA031000: AB_10610560, HPA039982: " "unprognostic (9.86e-3)" "unprognostic (7.55e-2)" "unprognostic (2.41e-2)" "unprognostic (1.56e-2)" "unprognostic (6.36e-2)" "unprognostic (3.10e-3)" "unprognostic (1.04e-1)" "unprognostic (5.25e-2)" "unprognostic (3.35e-3)" "unprognostic (8.39e-2)" "unprognostic (6.19e-2)" "unprognostic (2.41e-1)" "unprognostic (1.49e-1)" "unprognostic (7.25e-2)" "unprognostic (1.15e-1)" "unprognostic (5.24e-2)" "unprognostic (7.39e-2)" 5.0 2.8 1.0 28.9 1.1 146.6 3.9 1.3 2.1 3.4 3.0 5.9 4.4 9.5 2.3 4.1 2.0 6.9 1.6 1.2 3.4 1.3 4.1 8.4 39.6 2.7 2.0 2.2 0.9 0.7 0.8 3.4 2.1 2.8 8.2 1.5 3.0 1.8 0.7 1.2 10.2 26.0 2.2 22.8 7.2 1.6 2.2 24.3 1.6 2.3 47.6 10.0 1.2 4.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 30.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 6.2 0.0 0.0 0.0 15.6 42.5 0.3 0.0 0.0 0.0 0.0 0.0 9.0 0.1 43.8 0.0 0.0 4.0 8.2 12.0 0.0 0.0 1.4 0.0 1.4 0.0 0.0 0.3 0.2 0.0 0.1 0.1 1.2 0.0 6.9 0.2 0.0 0.0 0.0 0.0 4.7 20.6 39.6 0.0 33.4 0.0 163.6 27.8 88.4 54.8 20.4 62.6 45.9 73.9 64.6 27.9 46.6 56.9 40.8 169.7 45.6 27.6 9.3 57.5 60.9 1.0 1.1 1.3 2.1 1.2 3.4 2.7 2.0 2.1 2.2 2.2 4.2 5.2 3.2 6.6 0.0 249.5 2.8 0.3 0.2 3.4 0.3 4.4 6.0 0.6 0.0 1.4 0.0 0.0 0.7 152.3 0.2 0.0 0.1 0.3 0.5 0.4 5.2 0.0 8.8 1.2 0.0 0.6 4.3 16.8 0.5 19.0 1.8 1.4 0.8 24.9 0.0 1.0 0.0 0.0 21.9 60.2 1.1 1.2 91.1 28.4 20.6 21.5 0.4 86.5 1.5 0.0 0.0 0.0 22.6 272.1 0.3 0.0 0.3 1.2 0.2 0.0 0.8 2.0 0.1 0.1 2.0 2.7 0.8 223.6 4.6 0.4 0.3 TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9628.1;intestine: 11712.2" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 2508.6;Peritubular cells: 2306.4;Sertoli cells: 2866.2;Smooth muscle cells: 4563.9" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 41.6;non-classical monocyte: 63.1" "Lineage enriched" "Detected in many" 12 "monocytes: 63.1" "Cell line enhanced" "Detected in all" "BJ: 1913.4;BJ hTERT+ SV40 Large T+: 1641.8;CACO-2: 1531.4;EFO-21: 2145.6;fHDF/TERT166: 2094.4;hTERT-RPE1: 1499.7;LHCN-M2: 1377.1;U-138 MG: 1598.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467" Enhanced Approved Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Microtubules, Mitochondria" Cytosol "CAB001447: AB_564012, HPA019467: AB_1857245" "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" 2235.7 512.7 118.5 963.9 144.4 12.1 1680.5 126.1 215.9 3611.3 172.5 11712.2 451.2 9628.1 693.9 1954.6 4610.6 893.8 1583.5 119.6 120.4 774.5 302.8 1258.6 245.5 137.0 127.0 1643.4 218.6 65.3 254.6 348.0 129.2 4624.1 1154.6 22.9 461.8 6383.6 356.4 619.8 1948.4 7108.7 127.2 532.0 3148.4 202.5 138.2 52.2 723.2 152.4 59.9 5521.7 2331.2 130.0 17.5 5.5 293.3 8.2 140.0 123.8 226.7 1913.4 788.1 1641.8 609.0 1531.4 28.4 3.2 2145.6 2094.4 1.7 46.1 4.4 16.8 543.3 6.8 4.4 5.0 66.9 130.2 708.7 1.7 5.2 304.6 57.5 267.1 36.1 1499.7 3.3 4.5 3.3 6.7 1377.1 4.5 1.7 15.8 84.6 18.8 2.1 2.7 23.1 12.0 4.4 25.8 1.9 9.6 29.9 11.0 1.5 807.6 9.2 5.1 182.0 1598.8 276.9 14.4 86.6 8.9 8.8 21.7 9.1 7.7 6.2 1.8 2.7 0.1 0.3 41.6 0.5 3.6 0.1 0.0 3.2 5.1 0.2 0.1 0.3 0.0 63.1 1.6 0.5 2.1 118.5 144.4 126.1 215.9 119.6 120.4 137.0 127.0 129.2 127.2 138.2 130.0 264.8 38.5 6.1 4.6 10.3 63.9 453.4 248.6 10.8 9.9 74.0 2508.6 1.3 4.3 22.5 40.5 18.8 57.0 8.6 3.1 0.0 577.8 3.3 14.6 455.5 260.3 3.0 2.7 4.5 74.5 35.3 464.4 41.3 12.8 1.3 32.4 639.7 8.9 41.5 1.7 6.5 18.3 24.4 23.1 91.8 23.9 48.4 33.8 96.0 37.5 8.1 4.9 2.1 3.0 11.9 38.4 4.5 2306.4 3.2 414.0 12.1 2.2 23.0 9.9 2866.2 177.6 4563.9 6.0 13.7 8.6 60.9 32.2 15.1 8.3 3.1 62.0 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TAT ENSG00000198650 "Tyrosine aminotransferase" P17735 16 71565660-71577092 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Aminotransferase, Transferase" "Disease variant, Mental retardation, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "liver: 1272.2" "Cell type enriched" "Detected in some" 43 "Hepatocytes: 4164.8" "Cancer enriched" "Detected in some" 10 "liver cancer: 152.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (3.66e-3)" "unprognostic (1.29e-1)" "unprognostic (8.17e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "unprognostic (1.01e-2)" "prognostic favorable (6.51e-4)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (2.27e-1)" "unprognostic (3.73e-3)" "unprognostic (1.88e-1)" "unprognostic (1.27e-4)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" 0.1 0.0 0.0 0.1 0.0 0.1 58.9 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.7 0.1 0.0 0.0 0.4 1272.2 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.1 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.7 6.7 0.0 0.1 0.0 0.0 0.6 95.3 18.7 0.5 72.9 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.3 1.0 0.3 0.0 3.1 0.0 45.5 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.1 49.6 4164.8 0.0 0.0 0.0 0.0 0.0 72.3 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 2.7 0.2 0.3 1.0 0.0 0.0 0.1 1.3 1.3 0.0 0.0 0.0 3.9 0.0 0.1 0.0 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 TBC1D9 "GRAMD9, KIAA0882, MDR1" ENSG00000109436 "TBC1 domain family member 9" Q6ZT07 4 140620782-140756385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 91.6" "Cancer enriched" "Detected in all" 7 "breast cancer: 85.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.9" "Group enriched" "Detected in many" 37 "B-cells: 5.9;dendritic cells: 3.2;monocytes: 1.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000262, HPA006503" Uncertain Approved Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 35: Glandular cells - Unknown function" Cytosol "HPA000262: AB_2665956, HPA006503: AB_2667604" "unprognostic (1.41e-1)" "unprognostic (1.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.49e-2)" "unprognostic (3.00e-1)" "unprognostic (1.22e-2)" "unprognostic (9.17e-2)" "unprognostic (2.11e-3)" "unprognostic (2.64e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-3)" "unprognostic (6.77e-2)" "prognostic favorable (1.61e-6)" "unprognostic (2.17e-2)" "unprognostic (1.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.16e-2)" 18.2 9.2 7.2 15.2 7.9 2.0 48.7 22.5 9.4 12.9 35.2 7.3 8.2 8.3 7.8 9.1 10.0 13.8 8.5 8.4 15.3 15.7 12.6 16.3 15.1 7.9 9.6 15.9 9.1 9.8 6.3 20.5 15.4 14.6 6.6 21.0 8.8 21.3 2.2 3.2 12.8 7.7 6.4 33.7 16.8 3.3 12.9 5.6 5.8 6.9 19.4 15.8 7.1 3.3 0.9 11.9 10.9 9.4 26.0 24.3 22.3 15.3 16.3 10.8 13.7 2.4 10.4 0.1 9.5 19.9 13.4 2.4 13.7 10.8 10.1 0.0 7.7 7.0 8.5 10.4 9.4 0.9 1.1 20.1 17.7 9.4 37.2 31.2 30.3 3.7 0.0 0.0 10.2 12.0 1.6 0.1 1.7 12.7 10.4 7.7 17.9 18.1 12.3 22.0 16.0 11.4 15.8 27.4 10.5 18.4 6.4 0.4 47.7 28.3 8.5 18.6 13.3 0.0 0.0 0.1 17.2 1.3 15.7 0.0 1.7 0.0 0.0 1.3 0.0 5.9 0.0 0.0 2.9 2.9 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.7 7.2 7.9 22.5 9.4 8.4 15.3 7.9 9.6 15.4 6.4 12.9 3.3 49.4 54.5 9.3 4.6 42.1 4.6 10.6 21.4 4.0 35.4 91.6 39.4 8.1 17.2 15.1 55.2 4.2 14.1 14.0 8.3 7.9 13.6 0.5 49.4 20.9 32.6 7.7 0.4 54.8 17.2 4.7 15.1 8.2 61.4 0.0 8.0 17.2 23.9 18.3 10.1 66.2 6.6 24.4 39.3 30.3 1.3 13.1 44.8 8.8 78.7 39.5 43.5 1.0 27.6 2.6 12.2 5.8 26.7 25.0 16.3 6.1 5.7 15.9 7.6 0.0 2.8 11.1 0.8 1.7 10.4 3.8 43.2 3.7 16.0 3.1 16.0 TBX2 ENSG00000121068 "T-box transcription factor 2" Q13207 17 61399843-61409466 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 62.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.1;Collecting duct cells: 95.6;Muller glia cells: 139.8;Sertoli cells: 170.9;Smooth muscle cells: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 129.3;MCF7: 78.5;SH-SY5Y: 65.4;SK-MEL-30: 49.3;WM-115: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA008586, CAB013636" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "CAB013636: , HPA008586: AB_1080222" "unprognostic (6.18e-2)" "unprognostic (8.51e-2)" "unprognostic (4.50e-1)" "unprognostic (2.09e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.82e-1)" "unprognostic (3.49e-2)" "unprognostic (9.29e-2)" "unprognostic (2.10e-2)" "unprognostic (2.10e-1)" "unprognostic (2.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.45e-1)" "unprognostic (6.34e-3)" 21.1 3.7 2.9 2.6 3.4 0.0 16.1 2.7 4.6 14.5 1.7 9.8 4.9 22.0 14.1 7.1 15.7 4.5 19.9 2.2 3.2 31.7 4.9 62.8 1.0 3.8 4.1 10.2 3.6 2.1 6.2 24.7 3.8 16.3 1.8 6.3 4.2 27.5 8.1 5.6 11.4 4.6 2.3 13.7 11.5 5.4 3.9 0.8 15.9 5.8 0.5 31.2 13.0 2.2 0.5 1.9 0.0 129.3 4.2 4.4 15.6 22.4 21.2 1.0 0.2 3.6 0.4 0.0 1.6 3.3 2.5 0.0 2.4 0.0 0.4 0.0 8.8 2.2 0.0 6.4 14.0 0.4 2.1 8.0 0.2 23.4 1.3 0.3 0.0 0.0 0.5 0.0 1.4 78.5 0.0 0.4 0.1 0.0 9.4 0.0 5.3 0.2 0.0 31.0 0.3 65.4 0.0 0.0 49.3 0.2 1.6 2.5 0.0 2.9 0.0 7.3 4.7 0.1 0.3 0.0 17.6 0.0 43.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.4 2.7 4.6 2.2 3.2 3.8 4.1 3.8 2.3 3.9 2.2 12.7 0.0 0.6 2.3 0.1 0.6 0.3 0.0 0.0 134.1 0.4 1.1 11.1 0.0 0.0 95.6 22.9 0.4 0.5 0.0 1.9 0.1 0.8 1.4 45.7 12.2 0.0 0.0 0.1 0.0 0.4 13.7 0.5 1.6 0.0 0.1 12.1 0.0 0.9 1.7 0.0 0.0 0.0 1.0 1.8 1.1 39.4 1.1 1.8 5.6 0.0 139.8 0.0 0.0 0.1 0.0 0.0 47.4 0.0 0.5 0.0 25.1 0.0 13.4 170.9 0.8 104.0 0.4 0.7 0.1 0.3 0.3 0.9 1.1 0.0 0.2 TBX22 "CLPA, CPX" ENSG00000122145 "T-box transcription factor 22" Q9Y458 X 80014753-80031774 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "testis: 11.1;thyroid gland: 4.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HDLM-2: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (6.58e-2)" "unprognostic (6.31e-2)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX3 "TBX3-ISO, UMS, XHL" ENSG00000135111 "T-box transcription factor 3" O15119 12 114670255-114684175 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 178.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 613.9" "Cancer enhanced" "Detected in all" "prostate cancer: 49.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 103.0;BJ hTERT+: 97.3;RT4: 129.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA005799, HPA075876" Supported Nucleoplasm,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Cytosol "HPA005799: AB_1857817, HPA075876: " "unprognostic (3.27e-1)" "unprognostic (2.64e-1)" "unprognostic (2.84e-1)" "unprognostic (1.11e-1)" "unprognostic (3.40e-2)" "unprognostic (5.97e-3)" "unprognostic (1.56e-1)" "unprognostic (2.99e-2)" "unprognostic (9.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (3.06e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-3)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "prognostic favorable (3.28e-4)" 13.3 178.4 5.1 2.5 4.7 0.0 34.1 3.9 5.7 37.5 2.9 7.4 37.6 32.8 44.6 2.8 24.0 4.5 13.2 3.8 14.9 12.9 31.3 32.8 1.4 4.6 4.4 44.2 2.9 1.0 12.9 41.3 4.8 80.4 3.7 1.8 18.9 53.2 10.4 14.9 30.3 10.0 3.8 7.0 6.0 1.3 6.6 1.3 50.0 16.5 1.7 53.9 34.2 3.7 2.4 18.2 0.0 0.0 26.1 35.6 40.1 103.0 97.3 39.0 38.3 16.3 4.4 0.0 1.6 18.0 2.4 4.7 8.4 3.6 47.7 0.0 12.3 0.0 4.8 48.1 8.4 0.0 0.0 16.0 2.4 13.1 26.8 0.0 0.5 0.0 3.8 0.0 3.4 1.6 0.0 0.5 0.2 53.0 5.4 0.0 0.0 2.6 0.0 129.3 6.6 19.4 14.6 6.6 3.6 44.6 5.1 0.2 0.0 11.9 7.7 6.8 33.9 0.0 0.0 0.0 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.7 3.9 5.7 3.8 14.9 4.6 4.4 4.8 3.8 6.6 3.7 48.9 0.0 1.9 0.3 1.8 9.8 85.2 5.8 7.4 14.3 110.3 80.5 12.5 0.0 1.1 35.0 4.2 60.7 0.7 12.0 0.0 0.6 1.5 3.3 144.7 38.6 4.9 0.0 0.0 0.0 7.0 41.3 5.1 3.8 0.0 3.9 1.1 40.2 6.1 1.7 0.0 23.9 4.1 0.9 4.6 2.8 5.3 2.9 3.6 14.0 0.0 1.9 0.0 0.0 0.0 0.3 22.4 6.0 0.0 72.4 37.9 0.1 0.4 2.0 39.5 27.2 58.2 0.1 3.8 3.2 9.8 613.9 2.0 112.0 12.1 69.1 TELO2 "hCLK2, KIAA0683, TEL2" ENSG00000100726 "Telomere maintenance 2" Q9Y4R8 16 1493344-1510457 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041348, HPA041473" Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Cytosol" "HPA041348: AB_10794514, HPA041473: AB_10795593" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (2.64e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (2.94e-2)" "unprognostic (5.99e-3)" "unprognostic (1.47e-3)" "unprognostic (2.21e-1)" "unprognostic (6.75e-2)" "unprognostic (3.15e-3)" 12.3 13.2 7.3 7.6 7.2 11.3 13.4 8.8 11.0 15.2 5.7 12.6 8.9 14.1 1.1 14.4 15.1 3.7 13.2 6.9 6.4 13.6 14.8 11.6 8.1 10.2 7.6 14.4 12.2 4.3 12.5 4.8 7.6 15.8 1.4 1.8 11.4 4.8 17.0 14.4 14.4 2.4 6.4 18.6 11.9 10.0 7.6 5.8 13.2 4.9 3.1 13.6 13.9 8.3 19.7 28.8 8.8 16.8 3.4 3.6 33.9 30.5 5.7 14.4 10.4 37.0 18.3 28.8 25.8 4.9 7.1 20.5 6.3 11.6 2.7 16.9 55.1 16.5 36.7 21.8 5.7 21.0 23.9 7.0 4.3 13.4 2.8 4.9 8.6 24.6 43.2 10.1 5.8 66.3 24.9 56.1 28.2 6.9 23.9 73.5 12.3 29.4 5.4 18.3 36.8 20.6 26.5 24.8 9.8 3.3 23.2 25.3 13.8 31.2 21.7 30.5 25.8 18.2 12.6 53.3 9.9 29.3 26.7 0.0 5.7 2.9 4.1 7.2 3.9 4.1 2.9 3.4 6.9 6.0 3.1 2.5 0.5 3.4 10.7 4.3 2.7 4.7 7.3 7.2 8.8 11.0 6.9 6.4 10.2 7.6 7.6 6.4 7.6 8.3 15.8 0.0 2.7 18.9 15.2 6.9 7.8 10.4 10.2 13.7 12.7 9.8 1.6 11.5 6.3 9.2 12.5 25.5 9.1 19.4 5.9 8.2 2.0 8.4 11.0 9.6 2.4 10.8 5.3 7.2 20.2 11.4 15.8 9.2 2.5 21.2 8.9 12.3 19.6 18.5 6.4 17.2 8.2 11.8 7.0 1.9 7.5 8.6 8.8 10.3 13.3 17.3 8.2 8.5 7.0 6.9 5.5 14.7 8.7 8.8 13.7 6.3 5.1 20.1 13.1 9.9 11.4 9.8 8.2 10.3 6.5 22.0 9.6 19.0 23.5 5.1 TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 52.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.6;Breast myoepithelial cells: 7.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 27.0;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 11.9;T-47d: 23.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" 0.3 0.5 0.7 1.0 0.7 7.4 4.3 0.6 0.6 0.7 0.6 2.5 1.4 0.7 0.7 1.6 1.7 0.4 0.2 0.5 0.8 3.1 0.4 0.4 1.3 1.2 0.7 0.8 1.1 2.1 2.3 0.3 1.2 2.3 2.9 1.5 1.9 1.1 0.0 0.6 1.4 0.4 0.5 1.3 0.9 52.5 0.7 2.1 1.1 0.1 1.1 0.4 0.9 0.5 7.2 3.1 1.3 0.1 0.0 0.0 3.5 1.6 0.8 2.2 1.0 0.9 7.1 2.9 1.6 0.3 0.0 3.4 1.0 1.4 1.7 3.0 2.5 2.1 1.0 0.0 0.0 1.5 11.9 0.0 3.8 0.1 2.2 3.0 0.7 3.4 4.5 5.4 0.3 4.8 0.8 4.2 7.3 3.3 3.1 1.9 0.4 0.8 2.6 0.1 4.4 4.7 0.0 1.5 0.0 3.7 23.8 10.0 2.7 0.2 0.5 0.2 0.1 2.1 2.0 2.8 0.1 4.2 1.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.7 0.7 0.6 0.6 0.5 0.8 1.2 0.7 1.2 0.5 0.7 0.5 0.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.6 7.4 0.0 0.0 0.6 0.0 0.0 1.8 0.7 0.0 5.9 6.3 0.0 31.5 2.6 0.3 0.0 0.0 0.0 4.0 4.7 0.3 0.0 27.0 2.5 4.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.5 0.0 0.0 11.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.1 0.2 0.0 0.0 TFAP2B AP2-B ENSG00000008196 "Transcription factor AP-2 beta" Q92481 6 50818723-50847619 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 33.3;retina: 14.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 145.7;Bipolar cells: 76.4;Horizontal cells: 437.4;Melanocytes: 106.7" "Cancer enriched" "Detected in some" 8 "breast cancer: 12.1" "Group enriched" "Detected in many" 6 "cerebellum: 3.5;medulla oblongata: 3.9;midbrain: 9.0;pons: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 109.6;SH-SY5Y: 208.1" "Region enhanced" "Detected in many" "cerebellum: 10.0" "Low region specificity" "Detected in many" "HPA034683, HPA062942" Enhanced Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA034683: AB_10670966, HPA062942: AB_2684909" "unprognostic (2.02e-1)" "unprognostic (2.29e-2)" "unprognostic (4.27e-2)" "unprognostic (5.88e-4)" "unprognostic (9.76e-2)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (4.57e-1)" "unprognostic (6.58e-6)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (7.17e-3)" 0.1 3.4 0.0 0.0 0.0 0.0 8.2 3.5 0.1 0.1 0.0 0.1 0.0 0.0 33.3 3.9 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 3.9 9.0 0.0 0.0 0.0 0.6 0.2 10.2 0.0 0.0 14.8 6.4 0.7 0.0 8.6 0.0 0.0 0.6 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 109.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 35.5 0.1 0.2 208.1 0.0 0.8 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.1 3.9 9.0 10.2 0.6 1.1 0.2 0.2 0.0 0.0 0.0 0.0 11.7 0.0 0.0 145.7 76.4 43.0 29.7 0.9 0.0 0.0 51.5 8.4 14.9 0.1 0.0 54.8 0.0 17.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 437.4 0.0 0.0 0.0 0.0 1.5 2.0 0.0 0.5 106.7 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.7 0.0 11.8 0.0 0.0 0.3 1.9 0.6 31.1 4.3 4.9 0.2 0.0 0.0 0.0 TFE3 "bHLHe33, TFEA" ENSG00000068323 "Transcription factor binding to IGHM enhancer 3" P19532 X 49028726-49043410 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.5" "Group enriched" "Detected in many" 4 "granulocytes: 12.5;monocytes: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023881 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA023881: AB_1857931" "unprognostic (2.68e-2)" "unprognostic (2.89e-3)" "unprognostic (2.40e-2)" "unprognostic (5.36e-2)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (6.03e-5)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "unprognostic (4.32e-2)" "unprognostic (5.41e-2)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.19e-8)" "unprognostic (1.93e-1)" "unprognostic (8.77e-2)" "unprognostic (4.19e-2)" "unprognostic (6.25e-1)" 31.3 23.6 27.8 16.8 27.3 24.1 22.9 25.8 26.9 24.1 23.3 23.6 10.8 24.7 21.1 15.6 26.2 18.5 17.2 25.7 29.4 15.1 12.6 29.2 11.8 37.2 30.9 25.8 12.4 25.1 18.4 20.8 28.7 17.2 11.5 14.8 13.4 28.3 17.0 20.5 14.7 24.7 27.5 22.5 16.8 5.9 32.2 10.7 20.0 14.0 13.2 25.0 20.5 25.6 32.8 41.5 14.6 44.6 48.6 45.1 12.5 40.6 55.8 49.7 38.2 23.3 26.8 10.2 18.0 65.7 48.6 25.5 25.4 40.2 44.8 24.4 11.8 8.3 39.6 26.2 69.0 10.0 28.3 38.5 32.3 64.4 50.1 47.8 26.3 8.4 19.8 55.9 49.2 20.6 7.5 17.2 36.3 11.0 34.1 11.9 22.2 26.6 43.1 18.0 12.4 12.4 44.8 19.0 17.9 52.5 27.6 15.0 48.5 47.1 48.7 48.0 27.3 30.1 29.7 8.0 56.1 14.0 33.2 0.0 4.8 1.8 0.6 4.7 1.1 0.5 0.9 0.5 2.2 1.0 0.6 0.5 12.5 0.4 6.3 0.5 1.3 2.6 27.8 27.3 25.8 26.9 25.7 29.4 37.2 30.9 28.7 27.5 32.2 25.6 13.8 16.0 8.8 13.7 9.8 19.8 19.7 11.2 30.1 6.8 10.9 9.4 8.1 15.7 11.8 20.2 4.2 16.0 4.4 14.3 9.8 17.7 0.7 10.9 15.3 17.5 12.5 5.2 7.5 15.8 9.4 20.2 14.3 14.8 5.7 12.0 10.8 15.0 22.3 18.5 7.2 8.2 0.0 21.7 29.4 2.2 27.4 20.5 8.8 11.2 15.5 12.0 4.1 6.0 7.7 21.4 13.7 24.5 12.9 20.2 10.6 12.1 7.0 5.6 13.1 18.5 14.3 2.2 0.8 18.9 22.0 37.1 8.6 13.9 7.5 19.6 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 265.6;intestine: 264.4" "Cell type enhanced" "Detected in many" "Leydig cells: 92.2;Peritubular cells: 179.0;Sertoli cells: 223.5;Smooth muscle cells: 176.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 100.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB020844 Enhanced Supported "Focal adhesion sites,Cytosol" NA NA 800000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" Cytosol "CAB020844: " "unprognostic (5.80e-2)" "unprognostic (3.09e-2)" "unprognostic (5.34e-2)" "unprognostic (1.18e-1)" "unprognostic (6.64e-2)" "unprognostic (9.52e-2)" "unprognostic (1.89e-1)" "unprognostic (4.95e-2)" "unprognostic (4.19e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.06e-8)" "unprognostic (1.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.73e-5)" 65.5 17.0 4.8 22.7 5.1 1.0 52.8 4.6 6.9 119.0 4.4 264.4 14.5 265.6 12.4 38.2 143.2 14.4 48.5 4.6 4.7 26.6 9.7 54.7 4.8 5.6 4.6 78.6 8.2 8.6 8.2 19.7 5.0 87.6 23.9 0.7 21.0 80.8 13.1 28.5 61.7 106.1 4.7 33.0 78.5 10.2 5.1 1.4 26.8 10.5 4.9 171.1 73.6 4.4 13.3 16.6 25.9 0.0 25.4 46.1 0.3 70.8 64.8 43.6 30.1 6.6 4.5 0.0 65.1 62.3 29.1 20.6 6.0 13.3 56.4 0.1 0.3 17.5 29.1 3.7 67.4 0.0 19.8 31.1 18.7 27.5 16.3 100.0 29.2 0.0 1.5 0.0 51.9 0.1 0.0 1.6 1.4 1.4 16.2 0.0 30.9 0.1 12.5 6.6 0.0 19.0 27.5 0.2 14.1 20.9 0.1 1.7 82.4 79.8 19.2 21.4 31.8 0.1 0.1 0.2 34.9 0.8 49.6 9.5 0.0 0.1 0.2 0.0 0.3 0.9 0.9 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.3 1.6 1.3 4.8 5.1 4.6 6.9 4.6 4.7 5.6 4.6 5.0 4.7 5.1 4.4 76.9 6.4 4.8 0.0 0.4 12.6 23.9 34.8 14.8 0.4 4.1 71.5 13.4 5.7 3.4 7.3 0.0 1.2 1.5 1.8 7.9 33.3 1.2 3.6 76.2 48.8 0.0 11.0 0.1 22.5 1.2 64.4 4.6 2.9 6.3 35.3 29.6 0.3 14.6 0.0 0.1 4.7 0.0 0.3 15.4 3.3 92.2 9.3 40.9 2.8 4.2 7.0 0.0 3.5 0.1 28.4 2.2 179.0 1.4 20.1 13.3 19.7 1.1 1.4 223.5 17.4 176.0 1.5 3.6 1.9 11.2 1.8 2.6 20.3 5.3 4.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.0;stomach 1: 27.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 238.7;Early spermatids: 405.1;Paneth cells: 140.4;Proximal enterocytes: 130.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 44.0;CAPAN-2: 41.1;MCF7: 20.3;OE19: 37.4;SK-BR-3: 25.7;T-47d: 52.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" 0.2 0.0 0.2 4.7 0.1 0.1 4.0 0.1 0.4 6.3 7.4 34.1 43.0 1.5 2.4 25.5 13.7 6.2 0.0 0.4 0.1 5.8 7.1 5.2 0.4 0.2 0.4 0.1 6.4 7.5 1.7 1.6 0.2 4.0 13.2 0.1 20.8 5.3 0.7 7.3 37.4 0.5 0.0 0.5 27.0 2.5 0.0 0.2 6.9 0.0 2.6 4.1 6.0 0.3 0.3 8.3 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 13.0 41.1 8.2 1.3 0.0 0.1 10.4 0.6 0.0 0.0 0.5 0.2 0.0 0.7 2.9 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.3 0.0 20.3 0.0 0.3 0.9 37.4 0.2 0.1 0.0 6.2 1.4 6.8 0.2 0.2 1.6 25.7 0.0 3.3 52.2 0.2 0.0 0.1 1.0 0.1 0.0 1.7 2.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 3.9 0.4 3.1 2.4 0.0 0.6 3.3 1.2 0.0 0.0 0.0 0.0 3.8 1.2 0.2 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 0.0 0.0 0.3 0.1 9.6 13.7 0.3 1.9 0.0 7.0 21.0 0.0 0.0 20.3 6.3 0.9 34.3 42.1 31.3 0.0 32.1 0.8 238.7 19.6 21.1 405.1 31.2 1.1 0.5 12.5 0.0 0.9 23.6 4.2 0.6 52.5 13.2 4.5 0.1 0.0 7.3 2.7 0.0 0.9 50.9 24.4 0.3 0.3 36.5 1.8 0.8 3.6 0.0 0.1 0.0 0.0 0.5 1.4 21.8 140.4 1.2 0.2 6.5 130.4 8.0 86.1 0.0 0.0 0.0 3.4 4.3 4.8 8.0 0.1 40.2 4.3 0.0 62.1 25.6 TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 108.0" "Cell type enhanced" "Detected in all" "Early spermatids: 818.9;Late spermatids: 1315.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 99.9;BJ hTERT+: 98.7;BJ hTERT+ SV40 Large T+: 89.4;fHDF/TERT166: 154.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065357 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA065357: AB_2685479" "unprognostic (6.68e-2)" "unprognostic (8.50e-3)" "unprognostic (2.13e-3)" "unprognostic (2.92e-1)" "unprognostic (1.91e-1)" "unprognostic (9.79e-2)" "unprognostic (1.24e-2)" "unprognostic (4.83e-1)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (9.94e-3)" "unprognostic (1.04e-1)" "prognostic favorable (6.94e-4)" "unprognostic (1.49e-1)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" 9.3 15.7 18.4 16.4 45.2 67.9 8.7 22.3 27.4 9.6 20.2 9.9 8.4 14.3 5.9 17.6 12.9 16.6 8.0 27.5 21.6 6.9 5.6 12.5 15.9 31.7 21.4 32.3 6.4 10.6 24.2 19.7 32.2 5.6 10.5 24.7 10.9 8.4 23.1 18.9 11.3 14.5 26.1 18.5 14.1 108.0 25.4 27.8 10.4 10.3 19.9 18.7 12.8 64.0 0.0 19.0 70.7 0.5 11.4 9.6 21.2 99.9 98.7 89.4 34.4 2.8 10.3 7.4 0.2 154.3 13.7 20.8 5.0 18.3 39.2 38.2 30.8 0.0 9.1 0.4 13.8 21.4 13.0 11.3 12.6 26.1 5.2 25.2 23.9 14.0 1.5 21.3 28.6 0.7 29.4 9.4 22.5 11.9 4.8 25.7 35.9 7.4 5.5 2.7 28.5 41.5 14.7 1.9 0.1 32.8 0.0 25.1 36.4 34.8 0.1 0.8 5.0 14.4 25.0 10.9 12.3 18.0 16.6 24.2 4.4 17.1 4.8 6.3 5.9 1.3 2.5 3.6 2.9 1.7 1.5 2.5 11.7 3.2 4.9 1.0 0.8 2.6 18.4 45.2 22.3 27.4 27.5 21.6 31.7 21.4 32.2 26.1 25.4 64.0 108.9 6.4 19.4 77.4 91.9 121.0 57.2 50.6 167.4 76.8 76.0 92.8 15.9 84.4 45.6 14.7 127.2 77.2 228.1 163.5 3.9 13.4 818.9 262.0 230.0 59.7 25.2 22.3 150.8 22.0 67.1 71.4 137.1 158.7 21.0 34.8 53.2 14.1 51.1 218.7 33.3 117.3 61.1 167.9 70.4 1315.5 105.6 101.7 42.7 77.8 75.3 31.0 88.6 301.6 381.0 31.7 207.6 46.6 152.7 37.8 122.0 18.1 50.4 290.2 72.3 280.7 83.9 38.3 146.0 140.0 90.8 65.0 141.0 86.8 96.0 99.9 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM6SF1 ENSG00000136404 "Transmembrane 6 superfamily member 1" Q9BZW5 15 83107572-83144854 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 47.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;granulocytes: 44.4;Hofbauer cells: 50.9;Kupffer cells: 37.8;Langerhans cells: 46.4;Macrophages: 45.9;Microglial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 76.6;eosinophil: 195.8;neutrophil: 118.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 195.8" "Cell line enhanced" "Detected in some" "HEL: 23.2;HHSteC: 49.6;HUVEC TERT2: 27.7;JURKAT: 36.4;TIME: 68.3;U-698: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016051, HPA056857" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "HPA016051: AB_2203924, HPA056857: AB_2683259" "unprognostic (8.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-2)" "unprognostic (4.67e-1)" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (6.46e-2)" "unprognostic (3.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.70e-2)" "unprognostic (2.80e-1)" "unprognostic (2.55e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.15e-2)" "unprognostic (4.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" 6.5 3.9 5.4 5.2 6.0 5.3 4.6 7.7 8.8 3.3 6.3 2.6 2.0 2.8 2.1 3.1 2.8 3.7 9.6 5.2 5.6 1.9 2.3 10.7 5.7 6.8 6.0 1.7 1.2 1.8 0.9 7.8 6.6 2.1 2.6 2.8 2.9 1.3 47.3 1.8 2.6 3.9 6.9 6.2 2.1 3.6 5.4 2.2 10.4 21.8 3.0 3.8 1.5 7.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.3 5.6 0.0 0.2 0.0 0.3 0.1 1.0 0.0 0.3 0.0 3.7 0.0 0.0 0.0 0.3 23.2 0.0 0.0 49.6 1.6 0.1 0.2 0.0 0.0 0.1 0.3 27.7 36.4 0.9 0.0 0.4 0.0 0.0 3.0 0.6 0.0 0.0 0.0 4.2 0.0 0.1 0.4 1.2 0.3 0.2 0.0 1.9 0.5 0.0 14.9 68.3 0.6 0.9 0.1 0.3 2.1 0.0 17.0 0.1 3.4 0.1 76.6 31.7 195.8 5.0 13.4 0.0 0.3 0.5 0.8 18.9 0.9 0.1 0.8 118.1 5.0 6.4 2.6 0.0 11.8 5.4 6.0 7.7 8.8 5.2 5.6 6.8 6.0 6.6 6.9 5.4 7.6 30.5 0.0 6.0 2.9 0.9 2.4 0.1 0.4 0.6 1.6 0.5 1.8 1.2 1.5 0.8 0.0 0.0 0.3 7.5 0.0 0.0 0.2 13.1 0.6 0.2 16.7 0.0 4.4 18.7 2.0 0.4 1.5 0.0 0.3 44.4 0.0 7.9 0.1 50.9 0.0 22.4 0.0 0.0 37.8 46.4 7.4 0.9 45.9 3.6 46.9 19.4 0.5 16.5 2.0 1.9 0.4 0.0 0.0 0.7 0.1 0.0 0.0 1.4 1.3 0.0 1.4 0.6 13.1 7.5 0.1 1.7 0.3 4.2 0.1 0.0 0.1 TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.4;stomach 1: 46.0" "Cell type enhanced" "Detected in many" "Club cells: 282.4;Pancreatic endocrine cells: 302.2;Proximal enterocytes: 374.3;Respiratory ciliated cells: 624.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 69.7;OE19: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" 0.6 0.1 0.2 3.1 0.4 1.5 12.7 0.5 0.3 8.9 5.6 21.6 45.4 2.1 17.5 1.2 5.1 25.5 0.1 0.3 0.0 0.3 0.6 18.9 0.2 0.2 0.2 0.1 2.3 6.0 0.1 3.2 0.2 12.2 22.7 0.2 22.8 0.2 0.1 1.8 53.4 1.1 0.0 0.1 46.0 3.8 0.2 0.1 0.7 0.0 1.1 3.2 0.5 0.2 6.9 10.8 0.0 0.3 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.1 69.7 0.0 0.3 0.0 0.2 4.4 1.1 0.0 0.0 0.1 0.1 0.0 1.8 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.1 0.0 0.2 2.5 41.5 3.1 0.0 0.0 2.6 0.1 0.3 0.7 0.2 0.1 2.1 0.0 1.1 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.1 157.0 162.5 0.0 1.8 0.8 22.9 46.6 2.8 0.3 57.4 17.9 0.9 102.9 282.4 22.0 2.1 39.0 1.0 173.7 0.0 121.1 32.8 107.0 6.9 2.9 38.9 8.0 1.9 166.3 3.4 3.3 188.1 88.4 5.7 11.0 0.7 0.6 2.7 3.3 2.0 101.5 26.4 0.0 1.1 32.6 0.3 1.8 1.8 0.0 1.0 0.2 0.0 0.5 0.9 302.2 180.9 0.7 0.5 103.1 374.3 2.0 624.7 1.9 0.0 0.4 9.5 1.3 1.1 2.2 1.7 16.3 1.3 1.5 125.1 55.9 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 75.7;pancreas: 89.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 121.8;Alveolar cells type 2: 136.9;Distal enterocytes: 72.7;Proximal enterocytes: 164.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.8;BEWO: 21.8;CACO-2: 20.6;CAPAN-2: 48.3;OE19: 31.3;SK-BR-3: 41.2;T-47d: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" 0.3 0.7 17.4 3.2 32.2 0.2 11.5 27.6 29.9 16.4 12.8 21.2 35.4 1.6 18.3 10.9 15.5 11.3 0.9 17.0 20.7 16.4 1.1 75.7 0.3 31.5 28.5 1.4 89.6 22.2 31.0 4.4 29.0 22.0 21.0 0.1 31.8 7.1 0.0 12.9 27.5 0.8 22.6 0.3 27.4 1.5 26.8 0.4 44.9 0.0 2.5 2.9 3.4 42.8 26.8 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 20.6 48.3 0.1 1.2 0.0 0.0 11.7 0.0 7.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 12.1 0.1 0.1 1.1 31.3 0.0 0.0 0.0 0.7 0.4 8.5 12.4 0.1 0.0 41.2 0.0 3.6 33.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 17.4 32.2 27.6 29.9 17.0 20.7 31.5 28.5 29.0 22.6 26.8 42.8 0.2 121.8 136.9 0.0 0.9 0.0 2.3 18.0 0.6 0.0 30.4 15.2 0.5 42.9 56.0 16.5 0.0 33.5 0.1 72.7 17.6 39.1 3.7 20.1 1.4 0.6 21.7 0.0 0.2 38.5 2.2 0.6 45.3 13.1 1.3 4.9 0.0 0.0 2.4 0.0 0.2 63.0 34.6 0.0 0.2 7.9 0.3 0.6 0.0 0.0 0.6 1.7 1.0 0.0 55.3 22.7 40.1 1.2 0.6 12.2 164.2 33.9 43.8 0.0 0.0 0.0 2.3 1.4 0.3 2.1 0.4 7.3 1.0 0.1 38.6 9.1 TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 64.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.1;Kupffer cells: 11.8;monocytes: 8.0;Proximal enterocytes: 68.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cell line enhanced" "Detected in some" "CACO-2: 8.3;HMC-1: 3.8;THP-1: 2.9;U-937: 18.1" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" 3.7 1.8 0.5 5.8 0.8 0.7 1.1 0.4 1.0 0.3 1.2 10.2 64.1 0.4 0.1 0.6 0.8 2.9 0.8 0.4 0.7 3.2 2.2 11.9 3.5 1.3 0.7 0.3 0.9 0.1 0.2 5.6 1.6 0.3 7.3 0.0 0.6 0.4 0.2 0.2 57.0 4.1 0.5 5.7 1.4 0.5 3.4 0.7 0.3 0.2 1.6 2.0 0.3 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1.6 0.0 1.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.9 0.0 0.0 0.1 0.1 0.1 1.8 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 18.1 0.1 1.9 5.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.5 0.8 0.4 1.0 0.4 0.7 1.3 0.7 1.6 0.5 3.4 1.3 0.0 0.0 0.0 0.0 0.6 0.1 1.3 0.0 0.0 0.0 0.1 0.0 0.5 1.5 0.0 1.8 0.0 0.0 0.0 18.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.4 0.8 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.1 6.7 0.0 0.7 3.5 0.0 11.8 1.3 0.0 0.0 3.2 0.0 0.0 8.0 0.0 0.0 0.0 0.9 0.3 1.4 0.0 0.9 0.6 68.9 0.6 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 3.7 0.3 TMEM210 ENSG00000185863 "Transmembrane protein 210" A6NLX4 9 137170858-137172056 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 14.8" "Group enriched" "Detected in some" 68 "Early spermatids: 900.5;Late spermatids: 1815.1" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "plasmacytoid DC: 3.2" "Lineage enriched" "Detected in single" 33 "dendritic cells: 3.2" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 13.5" "Not detected" "Not detected" HPA066907 Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA066907: AB_2685747" "unprognostic (5.17e-2)" "unprognostic (5.04e-2)" "unprognostic (2.87e-5)" "unprognostic (4.18e-2)" "unprognostic (3.63e-2)" "unprognostic (3.14e-2)" "unprognostic (8.00e-2)" 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.3 0.3 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.6 1.3 0.0 0.0 0.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 900.5 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.7 1815.1 12.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.4 0.0 1.1 0.0 0.0 0.0 0.0 19.7 0.0 0.1 9.1 4.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 TMEM230 "C20orf30, HSPC274" ENSG00000089063 "Transmembrane protein 230" Q96A57 20 5068232-5113103 "Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 502.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009078, HPA061421" Uncertain Enhanced "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA009078: AB_1078345, HPA061421: AB_2684513" "unprognostic (1.39e-1)" "unprognostic (3.61e-1)" "unprognostic (3.73e-1)" "unprognostic (1.28e-1)" "unprognostic (3.71e-2)" "unprognostic (9.67e-3)" "unprognostic (5.85e-3)" "unprognostic (4.34e-3)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-2)" "unprognostic (9.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.09e-1)" "unprognostic (2.84e-2)" "unprognostic (1.55e-2)" 140.5 120.1 89.7 60.4 98.6 60.4 88.4 101.9 110.7 108.3 113.6 83.9 62.3 88.9 120.4 57.3 87.1 97.7 101.4 88.2 100.2 145.7 197.8 75.8 81.0 98.9 95.1 97.4 95.1 99.3 89.5 72.5 99.1 105.5 88.7 107.4 78.9 83.1 107.1 34.4 70.2 88.9 95.3 71.8 87.6 49.7 96.0 85.6 135.5 148.3 76.6 93.3 56.6 111.8 157.2 108.1 139.1 105.2 307.1 271.6 105.6 124.0 185.4 119.9 131.4 86.0 152.4 74.8 99.5 180.7 136.6 127.1 104.5 185.2 172.3 83.6 119.6 132.6 31.5 266.3 196.3 154.9 52.8 189.3 202.4 92.2 183.3 167.0 160.1 163.6 126.1 200.3 199.2 44.7 156.9 143.8 106.3 298.8 152.4 100.4 93.2 161.5 182.5 79.4 116.8 141.7 74.6 154.8 270.0 149.0 123.9 145.6 135.7 154.7 90.5 150.1 135.2 133.2 284.3 147.5 62.5 132.2 166.3 128.9 175.4 116.7 136.5 187.1 166.3 170.7 145.8 145.3 163.8 153.1 150.8 148.6 55.7 153.9 180.6 161.2 147.6 349.2 89.7 98.6 101.9 110.7 88.2 100.2 98.9 95.1 99.1 95.3 96.0 111.8 126.6 57.7 64.6 15.3 123.4 70.4 126.7 148.7 65.4 89.6 151.7 133.7 51.3 111.5 95.1 154.5 64.6 173.4 127.8 55.0 502.9 146.6 200.3 77.1 103.2 109.5 95.8 103.7 20.2 111.2 208.8 141.6 59.1 64.1 114.1 82.8 126.7 147.5 212.8 62.2 27.7 123.1 126.1 162.9 172.9 89.5 212.2 121.9 199.3 14.0 215.6 113.9 151.4 13.0 49.6 100.2 130.0 220.4 161.7 129.6 102.0 363.2 81.9 113.3 85.5 100.4 128.0 99.4 97.5 68.1 60.5 148.0 118.2 184.2 125.6 152.1 TMEM273 "C10orf128, Em:AC084727.5" ENSG00000204161 "Transmembrane protein 273" Q5T292 10 49154725-49188585 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 37.8;dendritic cells: 10.1;Hofbauer cells: 82.9;Macrophages: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "eosinophil: 269.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 269.0" "Cell line enhanced" "Detected in some" "HDLM-2: 214.8;HEL: 51.7;K-562: 101.4;U-266/84: 38.3;U-87 MG: 102.2;U-937: 91.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA058166 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA058166: AB_2683627" "unprognostic (1.33e-1)" "unprognostic (5.67e-4)" "unprognostic (1.34e-2)" "unprognostic (1.21e-1)" "unprognostic (4.50e-2)" "unprognostic (4.13e-2)" "unprognostic (5.86e-3)" "unprognostic (9.13e-3)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (5.11e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (2.86e-5)" "unprognostic (2.45e-2)" "unprognostic (2.22e-2)" "unprognostic (8.69e-3)" "unprognostic (1.24e-1)" 31.5 3.0 15.1 17.2 22.1 4.0 27.5 23.0 27.1 15.1 13.4 12.8 8.8 13.7 6.1 8.4 12.8 18.3 28.0 15.2 18.2 6.0 9.5 27.1 22.2 25.0 22.8 3.9 4.0 14.4 3.3 10.9 25.0 8.2 14.2 1.1 9.8 7.8 8.5 7.3 24.3 20.9 18.9 29.8 8.9 1.9 20.5 7.8 10.2 16.5 23.4 14.4 12.7 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 214.8 0.0 51.7 0.0 0.0 0.0 0.5 21.9 0.0 0.0 0.0 0.0 0.0 1.4 0.2 101.4 6.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.3 0.0 0.0 0.0 0.1 0.0 38.3 0.1 102.2 91.6 0.0 24.9 4.2 269.0 22.9 1.4 36.5 35.9 13.8 22.0 19.8 18.5 0.7 6.1 19.4 0.2 0.7 0.6 11.2 11.5 15.1 22.1 23.0 27.1 15.2 18.2 25.0 22.8 25.0 18.9 20.5 30.7 37.8 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.8 0.0 0.8 10.1 0.0 0.0 0.1 0.0 1.1 0.2 9.4 0.0 0.0 0.0 0.0 0.7 0.5 0.0 2.0 0.0 0.0 0.0 0.0 82.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.1 5.6 0.0 0.0 0.0 TMEM35B ZMYM6NB ENSG00000243749 "Transmembrane protein 35B" Q8NCS4 1 34981535-34985353 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 13.4;Club cells: 6.2;granulocytes: 8.8;Respiratory ciliated cells: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 115.3;CAPAN-2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051024 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 5: Breast - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "HPA051024: AB_2681316" "unprognostic (3.34e-3)" "unprognostic (2.77e-3)" "unprognostic (4.25e-1)" "unprognostic (2.12e-2)" "unprognostic (5.52e-2)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "unprognostic (7.51e-3)" "unprognostic (2.32e-1)" "unprognostic (9.41e-2)" "unprognostic (2.03e-2)" "unprognostic (1.86e-1)" "unprognostic (5.49e-2)" "unprognostic (4.53e-3)" "unprognostic (1.07e-1)" 48.9 36.0 12.6 25.1 12.5 13.6 40.1 12.4 18.5 41.6 16.9 27.4 16.6 36.2 39.0 15.4 41.3 41.0 32.3 12.4 13.1 36.8 40.1 44.2 40.0 13.8 12.8 32.5 29.6 29.8 21.8 63.4 13.7 30.4 26.6 2.2 25.8 34.8 8.6 13.3 27.6 30.1 13.7 32.5 24.4 22.6 13.4 29.7 44.7 20.4 30.9 36.2 33.3 14.4 25.8 19.5 4.2 7.3 115.3 67.1 9.3 27.7 46.2 19.1 25.8 19.4 113.1 12.6 42.1 28.4 30.3 27.2 8.1 23.4 15.0 49.2 12.9 27.2 9.0 23.1 63.2 18.0 27.5 67.7 21.3 17.4 36.6 39.1 38.3 26.8 17.5 36.2 34.2 16.2 13.3 18.6 20.2 0.0 13.6 17.7 37.3 4.0 53.6 24.9 11.1 3.5 42.4 0.6 39.5 21.3 10.3 27.9 39.4 25.6 24.0 22.7 15.8 20.9 12.7 8.9 25.7 29.4 22.2 161.3 101.2 112.4 188.7 118.6 202.9 108.9 205.0 208.3 71.3 89.9 177.7 179.9 31.4 165.4 100.4 159.5 232.4 182.9 12.6 12.5 12.4 18.5 12.4 13.1 13.8 12.8 13.7 13.7 13.4 14.4 0.6 22.4 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 6.2 0.0 0.0 0.1 0.2 0.0 0.0 1.0 0.0 0.3 0.7 2.1 0.0 0.0 0.0 0.2 0.2 2.0 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 15.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 TMEM43 "ARVD5, DKFZp586G1919, LUMA, MGC3222" ENSG00000170876 "Transmembrane protein 43" Q9BTV4 3 14125015-14143680 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cardiomyopathy, Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019198 Approved NA NA 34000 "Cluster 5: Granulocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA019198: AB_1858118" "unprognostic (3.65e-3)" "unprognostic (2.52e-1)" "unprognostic (4.03e-2)" "unprognostic (4.66e-1)" "unprognostic (5.45e-3)" "unprognostic (1.72e-1)" "unprognostic (1.28e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (5.77e-2)" "unprognostic (5.45e-2)" "unprognostic (1.35e-3)" "unprognostic (2.19e-1)" "unprognostic (9.78e-2)" "unprognostic (1.18e-1)" 75.4 34.3 23.1 36.8 23.8 21.0 61.3 23.0 25.3 66.8 23.5 56.7 23.5 89.1 31.0 69.5 63.9 47.1 64.7 23.2 25.0 27.7 19.6 58.1 30.2 27.5 25.1 82.6 27.3 25.6 30.6 57.6 25.9 43.3 29.4 15.9 37.9 65.2 60.8 108.7 40.0 82.5 23.6 31.2 34.8 15.2 25.5 26.0 47.0 45.8 33.7 56.1 66.4 25.2 41.5 45.7 44.1 58.3 173.4 180.6 104.6 80.1 164.8 129.9 93.0 37.5 54.1 19.5 55.7 201.3 64.3 88.3 47.1 70.9 92.9 48.7 38.0 35.3 45.6 53.8 109.3 51.4 40.4 136.0 173.6 107.9 133.0 103.6 94.8 36.2 56.1 47.8 76.6 54.3 23.4 43.2 48.4 62.8 75.3 32.2 46.8 78.2 59.4 70.4 12.9 35.5 101.0 59.3 66.5 37.3 37.5 74.3 86.4 118.7 63.7 120.6 76.0 32.1 54.3 25.1 89.3 68.4 108.7 81.3 51.5 100.3 68.7 45.5 64.0 36.8 66.8 62.7 67.4 31.6 44.5 49.0 157.2 79.9 49.2 42.6 65.7 69.7 23.1 23.8 23.0 25.3 23.2 25.0 27.5 25.1 25.9 23.6 25.5 25.2 44.2 137.8 46.8 17.9 16.8 43.7 32.2 31.0 39.9 6.2 19.9 29.7 13.4 15.7 52.9 18.4 14.6 31.2 43.2 9.3 0.0 34.9 0.6 17.3 58.1 37.4 4.9 22.5 24.1 10.0 65.6 68.0 20.9 34.4 28.4 16.1 23.6 8.9 17.8 6.7 20.6 8.3 8.2 16.1 33.5 3.9 43.2 19.8 30.2 15.9 26.8 8.4 16.5 30.2 23.9 22.4 9.7 70.7 15.6 35.8 8.8 9.0 16.2 8.6 32.9 43.6 39.3 5.6 12.0 44.1 45.5 37.5 32.1 17.6 11.5 30.2 TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.5;intestine: 136.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 325.6;Paneth cells: 221.6;Proximal enterocytes: 288.7;Respiratory ciliated cells: 133.9;Undifferentiated cells: 122.2;Urothelial cells: 162.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 3.0;naive CD4 T-cell: 3.6;neutrophil: 11.7" "Group enriched" "Detected in many" 14 "granulocytes: 11.7;T-cells: 3.6" "Group enriched" "Detected in some" 5 "OE19: 333.1;RT4: 133.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" 0.7 0.6 1.5 8.3 1.6 1.1 13.2 1.9 1.8 14.9 7.6 95.1 136.4 1.1 13.6 66.5 21.7 24.1 0.1 2.1 2.0 20.6 24.7 6.0 0.9 1.5 2.8 0.2 1.2 12.4 4.2 1.4 1.5 3.6 94.6 0.4 15.4 8.2 0.3 25.4 127.4 2.8 0.9 0.8 24.3 0.3 2.0 0.4 6.5 0.0 15.0 30.8 27.3 1.4 0.1 0.1 0.1 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 39.1 16.8 0.2 7.0 0.0 0.2 22.3 0.0 0.0 0.0 0.1 0.5 0.3 2.1 40.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.2 0.1 0.0 13.3 0.2 1.5 0.2 333.1 49.2 0.3 0.1 2.6 21.0 133.1 4.1 0.6 0.2 10.8 0.1 0.1 37.1 0.2 0.3 0.2 0.3 0.4 0.1 0.2 0.1 0.4 0.1 0.3 0.1 1.2 0.5 0.1 0.2 0.1 0.2 0.2 3.0 0.8 0.0 0.4 3.6 0.6 11.7 0.5 0.1 0.3 0.5 0.9 1.5 1.6 1.9 1.8 2.1 2.0 1.5 2.8 1.5 0.9 2.0 1.4 0.1 19.2 12.5 0.3 1.1 3.3 16.4 29.1 0.0 0.1 6.7 2.5 0.8 18.6 68.8 46.0 0.0 3.8 0.0 325.6 13.7 26.9 0.4 27.7 2.9 1.0 55.4 0.0 0.8 8.6 0.8 0.8 17.9 29.5 2.5 0.3 0.4 8.4 0.5 0.0 0.4 49.3 20.3 0.6 0.4 0.3 0.3 2.9 3.6 2.8 0.1 0.1 0.0 0.0 0.3 50.2 221.6 0.0 0.0 23.8 288.7 1.4 133.9 0.2 0.0 0.7 3.6 0.1 0.2 4.4 20.9 0.4 1.8 0.1 122.2 162.0 TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 59.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 999.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.4" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Focal adhesion sites" "HPA021134: AB_2205162" "unprognostic (5.28e-2)" "unprognostic (2.60e-1)" "unprognostic (5.37e-2)" "unprognostic (4.62e-2)" "unprognostic (3.93e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (2.88e-2)" "unprognostic (2.19e-2)" "prognostic favorable (6.96e-4)" "unprognostic (3.00e-1)" "unprognostic (1.34e-1)" "prognostic favorable (1.02e-5)" "unprognostic (1.15e-3)" "unprognostic (1.84e-2)" "unprognostic (4.07e-2)" "unprognostic (2.29e-2)" 12.8 12.0 5.7 4.4 9.2 6.7 12.1 6.8 8.3 6.8 6.3 14.2 16.4 8.9 6.8 6.0 7.0 6.2 13.9 5.7 7.2 18.3 59.5 10.5 4.0 8.5 8.5 10.6 8.3 6.3 10.1 3.9 8.5 7.2 6.9 7.1 7.2 3.3 7.6 6.6 14.6 4.2 5.8 6.3 10.1 34.9 8.8 3.3 7.9 3.7 2.1 7.5 6.1 15.4 12.9 14.7 13.0 9.6 16.6 12.5 15.6 3.8 11.1 7.2 10.5 4.7 39.9 4.1 11.8 3.6 27.4 11.5 3.6 7.8 3.8 6.5 9.2 4.7 6.0 22.7 16.5 3.7 16.6 14.8 11.9 14.4 3.1 7.9 4.0 9.1 2.0 5.1 4.3 7.7 4.5 11.2 7.6 9.9 8.5 6.8 1.8 40.0 21.6 13.4 9.0 8.7 4.1 15.7 21.3 9.3 4.8 9.9 1.7 5.3 8.8 7.5 4.7 3.7 4.7 2.3 13.6 9.6 6.3 14.1 12.9 6.3 7.3 23.1 6.3 13.9 7.4 6.3 6.6 14.8 3.5 4.5 1.4 7.8 16.2 99.4 8.1 7.6 5.7 9.2 6.8 8.3 5.7 7.2 8.5 8.5 8.5 5.8 8.8 15.4 10.9 6.4 12.0 8.1 3.5 1.7 9.5 24.2 1.8 6.9 9.0 7.6 35.5 10.0 20.4 20.2 4.2 14.5 9.5 53.1 45.0 18.6 188.3 14.0 4.6 8.5 14.4 10.1 2.9 25.7 15.5 6.9 8.2 5.7 6.3 8.6 10.0 93.0 34.3 18.5 3.6 22.6 44.7 12.6 0.7 999.9 9.0 14.0 8.8 1.9 3.8 17.1 5.2 3.0 4.8 17.5 51.3 12.4 2.6 8.9 74.3 45.9 32.8 13.8 26.3 3.7 10.6 15.6 13.2 3.9 2.3 9.3 3.7 8.3 18.0 12.7 TMEM63C "C14orf171, CSC1, DKFZp434P0111, hsCSC1" ENSG00000165548 "Transmembrane protein 63C" Q9P1W3 14 77116568-77259495 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;pituitary gland: 41.9" "Cell type enhanced" "Detected in some" "Early spermatids: 9.5;Enteroendocrine cells: 19.2;Excitatory neurons: 25.8;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 16.1" "Cancer enhanced" "Detected in many" "breast cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 18.5;Karpas-707: 24.1;RPMI-8226: 12.7;SCLC-21H: 32.5;SK-BR-3: 29.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030657 Uncertain Approved Centrosome NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Centrosome "HPA030657: AB_10601699" "unprognostic (2.74e-1)" "unprognostic (1.79e-2)" "unprognostic (2.30e-1)" "unprognostic (4.30e-8)" "unprognostic (2.85e-1)" "unprognostic (5.26e-2)" "unprognostic (2.68e-3)" "unprognostic (1.61e-3)" "unprognostic (2.51e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-2)" "unprognostic (1.14e-1)" "unprognostic (2.90e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.34e-7)" "unprognostic (5.90e-3)" 0.2 9.6 9.2 0.6 5.9 0.8 3.3 28.7 10.5 2.6 0.0 4.5 1.2 0.1 4.5 6.4 0.2 0.2 0.9 5.6 24.6 0.5 0.1 0.5 0.3 4.5 8.3 0.1 4.8 1.5 41.9 0.7 16.9 0.2 3.0 2.4 2.7 0.0 0.5 9.7 2.7 0.6 4.2 3.3 1.9 11.3 18.2 0.1 2.2 0.4 0.3 0.0 7.1 4.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 18.5 3.4 0.0 3.0 2.5 3.8 1.5 0.0 1.2 1.4 0.3 1.8 0.0 0.0 3.2 0.1 0.0 7.5 0.0 0.2 0.0 0.0 8.7 0.0 24.1 0.0 9.3 2.6 0.1 0.8 0.0 0.0 0.0 1.2 12.7 0.3 0.0 32.5 4.9 0.4 29.1 0.0 0.6 2.8 1.6 0.0 0.0 5.9 0.0 0.0 1.9 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 0.1 9.2 5.9 28.7 10.5 5.6 24.6 4.5 8.3 16.9 4.2 18.2 4.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 3.3 2.2 0.8 0.7 0.0 1.7 0.0 2.1 0.0 1.5 3.8 1.9 0.0 9.5 0.3 0.4 0.1 19.2 0.0 25.8 0.2 0.1 0.3 0.0 2.4 0.0 0.2 0.0 0.0 2.7 3.3 22.2 3.0 4.1 0.0 0.0 6.2 0.0 0.2 0.0 3.7 0.6 0.3 0.0 16.1 1.1 0.2 7.0 0.4 0.1 0.0 0.5 0.2 0.1 0.6 0.0 0.0 0.3 0.6 0.1 2.4 0.0 0.0 0.2 0.7 0.7 0.1 TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 40.6;Theca cells: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" 2.8 2.7 2.6 2.2 2.2 0.3 3.2 2.1 2.8 2.3 3.8 1.5 1.4 2.2 1.0 2.3 2.6 4.0 2.9 2.1 2.6 9.5 2.6 3.5 4.7 3.1 2.7 7.1 3.4 5.4 2.2 4.3 2.5 1.6 1.8 5.7 2.7 1.4 2.9 17.6 2.0 1.9 2.7 4.9 2.1 2.3 4.0 1.6 2.1 2.5 2.5 2.3 3.6 4.5 0.0 0.2 0.6 3.1 2.7 0.0 0.1 0.6 0.5 0.5 0.5 0.0 0.4 0.0 1.2 0.6 3.0 0.3 0.2 0.1 0.3 0.2 1.9 0.2 0.1 0.0 2.1 0.0 2.8 3.8 1.2 0.1 0.2 0.7 1.7 1.8 0.6 0.0 1.3 1.7 0.0 0.0 0.2 0.5 1.6 0.0 5.1 0.0 17.5 3.8 1.0 1.3 1.0 3.2 1.4 1.1 3.9 0.4 1.9 0.5 0.2 0.1 0.1 3.2 2.7 0.0 1.1 0.0 1.1 0.0 1.9 0.1 0.2 1.4 0.5 0.0 0.2 0.4 3.4 0.1 0.4 0.8 0.0 0.1 0.5 2.0 0.5 0.8 2.6 2.2 2.1 2.8 2.1 2.6 3.1 2.7 2.5 2.7 4.0 4.5 1.9 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 5.2 3.5 1.8 2.2 0.0 0.7 11.0 8.4 0.5 1.4 0.6 7.9 7.8 12.2 1.1 1.9 2.1 3.5 0.0 0.5 8.0 0.3 1.7 1.1 1.0 0.0 3.0 3.9 1.6 40.6 0.0 0.8 0.8 0.0 12.7 0.8 12.1 2.1 8.3 0.0 3.7 2.3 2.6 0.0 2.0 0.1 7.4 0.1 1.9 0.4 0.6 0.0 8.3 0.4 4.8 6.6 0.4 1.2 7.8 2.6 0.2 0.3 2.3 0.7 17.4 0.2 0.4 TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6;choroid plexus: 10.5;pituitary gland: 9.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Spermatocytes: 2.6;Spermatogonia: 3.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;EFO-21: 2.7;JURKAT: 10.7;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" 0.7 6.2 14.2 0.5 14.1 0.0 0.4 14.0 18.0 0.7 10.5 1.0 0.4 0.5 0.7 1.5 0.6 0.2 0.7 14.1 19.3 2.3 0.8 1.0 0.8 19.6 15.7 1.5 0.2 0.1 9.9 0.4 19.2 0.5 0.3 0.7 0.5 1.0 3.6 0.7 0.5 0.4 16.0 0.7 0.3 1.5 18.7 0.5 0.9 1.2 0.8 0.6 0.9 14.9 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 2.7 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 1.8 0.0 1.2 0.0 0.5 10.7 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.1 1.2 0.0 0.3 0.1 0.1 0.3 2.3 0.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.4 0.4 14.2 14.1 14.0 18.0 14.1 19.3 19.6 15.7 19.2 16.0 18.7 14.9 1.9 0.0 0.0 0.3 0.0 0.8 0.2 0.5 0.0 3.8 0.2 0.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.4 0.5 0.2 0.0 0.7 0.0 0.0 1.7 0.4 0.1 0.4 0.0 0.1 0.0 0.1 0.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.4 1.5 0.6 0.3 0.0 1.9 0.1 1.4 0.0 0.0 0.3 1.2 0.0 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.0 1.1 1.0 2.6 3.2 0.0 0.9 0.1 0.2 0.1 0.0 0.2 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 30742.3;Langerhans cells: 57681.0;monocytes: 48133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Vesicles, Cytosol" "CAB033806: AB_2256019" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.72e-2)" "unprognostic (3.27e-2)" "unprognostic (7.98e-3)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.20e-4)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" 6173.6 4217.0 3255.7 5088.7 3773.0 8722.4 4452.0 3539.2 4521.9 3685.7 2999.1 4327.1 1776.8 3731.3 2877.9 2069.6 2709.3 4129.3 2652.4 3319.4 3573.5 3300.1 2360.4 6225.5 10448.1 4064.7 3620.0 2592.1 1852.6 483.2 1053.7 2450.2 4203.0 2335.6 3793.9 273.3 1886.8 2441.9 816.5 1962.4 3671.2 3340.7 4219.2 7935.5 4690.0 486.8 3591.8 6377.6 1648.7 1475.0 7233.8 5168.6 2907.2 4467.6 5980.6 4886.3 9387.7 14881.1 11264.5 12247.2 23.0 3083.9 8032.6 2344.3 4005.4 1016.1 4865.3 1417.1 2900.6 9443.7 4198.0 2564.2 1411.5 2072.7 3135.4 8343.4 80.9 1771.0 2621.8 12.9 2619.8 6994.8 14038.1 5755.3 2911.9 2781.9 2412.7 5704.5 14335.9 3714.1 230.0 22.0 8424.8 2121.5 8390.5 15083.5 3384.1 2853.1 3337.3 6352.0 3321.0 5858.5 14234.5 1720.4 994.2 422.9 4461.8 207.4 583.3 6898.2 5536.5 6961.4 11607.2 3383.5 1647.5 19441.4 3123.6 4432.5 3490.6 2774.8 5183.2 2860.5 2499.5 42940.3 34738.5 50992.6 21474.2 33907.1 18326.4 18757.1 23777.1 23343.2 31253.2 16919.4 19802.1 20330.2 35862.9 18444.5 37523.3 12797.6 34088.1 86809.5 3255.7 3773.0 3539.2 4521.9 3319.4 3573.5 4064.7 3620.0 4203.0 4219.2 3591.8 4467.6 6885.8 5253.2 4939.6 35.9 6293.8 8836.3 2708.7 10515.3 296.5 332.9 2318.3 1124.2 106.9 3484.4 8003.6 6882.2 22.9 283.0 9136.2 9016.2 2181.5 17304.6 142.1 2613.2 4698.0 9239.4 1765.0 1339.1 54.3 23029.4 511.7 4800.1 2728.9 5047.4 4380.4 4646.7 6638.0 1088.5 30742.3 62.2 81.0 4883.9 14806.8 20982.2 57681.0 343.6 3932.0 17648.1 6349.9 212.7 48133.8 86.7 20882.8 19.6 102.1 25113.5 5826.4 6035.9 2541.8 3272.5 6888.7 835.1 2596.4 99.4 5732.4 1018.2 5450.7 58.2 126.3 933.7 9528.5 454.8 12719.6 3874.8 3140.6 9064.0 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFSF8 "CD153, CD30LG" ENSG00000106952 "TNF superfamily member 8" P32971 9 114893343-114930595 "Cancer-related genes, CD markers, Predicted membrane proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.7;lymphoid tissue: 26.9" "Cell type enhanced" "Detected in some" "B-cells: 8.2;dendritic cells: 6.5;Kupffer cells: 6.5;Macrophages: 8.4;Microglial cells: 5.6;monocytes: 5.4;Plasma cells: 9.3;T-cells: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 50.9;SuSa: 23.3;U-698: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (8.82e-2)" "unprognostic (6.56e-3)" "unprognostic (7.79e-2)" "unprognostic (6.05e-2)" "unprognostic (2.67e-1)" "unprognostic (5.58e-3)" "unprognostic (5.26e-3)" "unprognostic (1.82e-2)" "unprognostic (2.37e-1)" "unprognostic (1.24e-1)" "unprognostic (1.70e-1)" "unprognostic (2.02e-1)" "unprognostic (4.75e-2)" "unprognostic (3.01e-2)" "unprognostic (2.76e-2)" "unprognostic (9.61e-2)" "unprognostic (1.82e-1)" 3.3 1.4 0.5 13.9 0.7 18.7 2.0 0.5 0.7 1.9 0.9 2.0 0.7 0.8 1.8 1.7 0.8 5.0 0.9 0.4 0.6 0.8 2.2 2.5 23.4 1.1 0.6 0.7 0.8 0.4 0.2 2.8 0.8 0.6 2.4 0.0 0.6 0.6 0.2 0.4 5.1 1.7 0.8 7.4 2.5 0.3 1.5 26.9 0.8 0.4 22.2 5.9 0.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 40.8 0.0 0.0 0.0 0.0 20.8 0.0 6.0 10.1 19.8 1.8 23.7 14.1 10.7 2.4 26.2 19.6 6.2 1.8 1.4 6.5 9.8 13.0 0.5 0.7 0.5 0.7 0.4 0.6 1.1 0.6 0.8 0.8 1.5 1.4 0.2 0.0 0.0 0.0 8.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.5 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.4 0.1 0.0 0.0 0.5 1.1 0.0 1.3 0.0 0.7 0.1 3.7 0.0 0.1 0.0 0.0 6.5 4.8 0.0 0.0 8.4 0.0 5.6 5.4 0.0 2.1 0.0 0.1 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 29.3 0.0 0.0 0.0 TNIP3 "ABIN-3, FLJ21162, LIND" ENSG00000050730 "TNFAIP3 interacting protein 3" Q96KP6 4 121131408-121227466 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.4;urinary bladder: 4.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.7;Distal enterocytes: 19.1;Early spermatids: 13.8;Late spermatids: 46.2;T-cells: 17.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 6.2" "Lineage enriched" "Detected in single" 10 "T-cells: 6.2" "Cell line enhanced" "Detected in some" "HDLM-2: 7.4;hTEC/SVTERT24-B: 8.0;U-138 MG: 30.9;U-266/70: 8.8;U-266/84: 9.3;U-87 MG: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043063 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "HPA043063: AB_10793989" "unprognostic (2.89e-3)" "unprognostic (2.60e-1)" "unprognostic (5.23e-3)" "unprognostic (8.75e-5)" "unprognostic (9.62e-3)" "unprognostic (2.14e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (2.80e-1)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.35e-2)" "unprognostic (2.84e-7)" "unprognostic (3.35e-2)" "unprognostic (6.51e-2)" "unprognostic (3.51e-1)" "unprognostic (8.78e-2)" 0.7 0.1 0.6 6.4 0.6 1.0 0.1 0.4 0.9 1.3 0.0 0.5 0.6 0.2 0.1 0.4 0.1 1.1 0.1 0.9 0.5 0.2 0.4 1.6 2.6 1.9 0.4 0.1 0.2 0.0 0.0 0.0 2.2 0.1 0.4 0.9 0.7 0.0 0.5 0.2 0.9 0.5 0.1 0.9 0.7 0.6 0.4 1.9 0.1 0.0 3.2 4.2 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.3 0.1 0.4 0.5 0.1 0.1 1.1 0.1 0.1 0.2 2.8 4.6 0.0 0.0 0.7 0.9 7.4 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.1 0.0 8.0 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 30.9 0.6 2.5 0.1 8.8 9.3 0.2 6.3 0.3 1.0 0.6 0.1 0.0 2.5 0.0 1.8 0.0 1.1 6.2 0.0 0.1 0.5 2.8 0.3 0.0 0.1 0.0 0.7 0.6 0.6 0.6 0.4 0.9 0.9 0.5 1.9 0.4 2.2 0.1 0.4 0.8 0.2 3.2 21.7 0.7 1.8 0.1 0.2 5.7 0.0 0.0 0.4 0.1 0.6 0.0 4.9 0.0 6.2 0.0 2.4 19.1 0.0 0.2 13.8 0.0 0.1 1.4 0.0 0.0 1.5 1.1 0.0 0.3 2.0 0.2 7.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 4.1 0.8 2.7 46.2 0.3 9.5 0.0 0.0 0.1 0.3 2.1 0.5 0.1 0.7 3.7 0.0 2.4 0.1 0.0 0.1 1.7 1.3 0.0 0.7 1.1 0.4 0.4 0.0 0.4 0.0 17.8 0.0 9.8 0.1 TNNI3K CARK ENSG00000116783 "TNNI3 interacting kinase" Q59H18 1 74235387-74544428 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 58.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 27.0;Early spermatids: 32.0;Late spermatids: 6.6;Proximal tubular cells: 8.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.0" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (1.04e-2)" "unprognostic (1.34e-2)" "unprognostic (3.83e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-1)" "unprognostic (3.40e-2)" "unprognostic (3.05e-1)" "unprognostic (2.48e-3)" "unprognostic (2.00e-1)" "unprognostic (9.66e-2)" "unprognostic (5.04e-2)" "unprognostic (1.80e-1)" "unprognostic (3.59e-3)" "unprognostic (4.88e-3)" "unprognostic (1.20e-1)" "unprognostic (8.80e-2)" "unprognostic (8.77e-2)" 1.8 1.4 3.6 0.3 3.6 0.1 1.4 4.9 7.2 1.0 2.0 2.0 0.4 1.3 2.5 0.6 1.5 0.4 58.7 3.7 3.9 3.4 0.4 0.9 0.4 3.3 3.2 1.5 0.4 0.7 2.3 0.0 3.6 1.1 0.5 5.2 0.8 0.4 1.5 1.6 0.8 0.9 3.5 1.4 1.1 4.0 3.5 0.4 1.0 0.6 0.5 1.4 0.9 4.8 0.0 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.2 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.6 3.6 4.9 7.2 3.7 3.9 3.3 3.2 3.6 3.5 3.5 4.8 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 1.2 0.2 0.3 27.0 0.0 0.1 1.8 0.0 0.0 0.0 0.1 1.9 0.1 32.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.0 8.0 0.1 0.5 0.0 0.6 0.8 0.5 1.4 0.0 0.3 0.1 0.1 0.0 0.0 0.2 TNS2 "C1-TEN, KIAA1075, TENC1" ENSG00000111077 "Tensin 2" Q63HR2 12 53046969-53064379 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 109.3;Hepatic stellate cells: 93.1;Leydig cells: 141.7;Peritubular cells: 114.0;Sertoli cells: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 114.2;ASC TERT1: 78.1;HHSteC: 59.9;HSkMC: 86.2;hTERT-RPE1: 61.9;TIME: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034659 Approved NA Yes "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA034659: AB_10603349" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (5.21e-3)" "unprognostic (1.86e-1)" "unprognostic (3.59e-2)" "unprognostic (7.26e-2)" "unprognostic (6.29e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-2)" "unprognostic (8.97e-3)" "prognostic favorable (1.72e-4)" "prognostic favorable (9.32e-4)" "unprognostic (4.46e-2)" "unprognostic (1.09e-2)" "unprognostic (8.46e-2)" "unprognostic (1.47e-1)" "unprognostic (2.76e-2)" 156.3 66.9 59.3 14.8 66.2 0.3 121.6 46.4 57.8 121.2 33.3 79.0 14.4 98.8 14.0 28.3 121.0 32.5 99.6 43.7 49.2 67.3 66.5 83.4 15.8 58.0 63.5 104.1 34.6 17.0 43.3 33.1 54.0 66.3 11.5 6.0 35.7 41.1 69.0 42.1 56.7 28.5 50.8 79.5 58.2 15.9 58.3 7.2 80.6 58.8 6.4 82.6 81.1 57.9 2.0 21.2 2.7 2.2 114.2 78.1 0.7 11.8 27.1 6.2 3.2 1.4 5.7 0.1 25.3 32.1 2.6 1.5 0.1 7.8 2.4 0.5 0.8 0.4 25.5 11.3 59.9 0.3 0.5 86.2 0.3 7.9 4.7 61.9 36.3 0.4 0.6 0.3 24.9 5.1 0.2 0.4 1.9 1.4 5.8 0.7 6.6 0.3 8.2 0.4 1.2 2.7 4.4 2.4 8.8 1.6 26.1 0.7 52.1 12.9 14.8 4.7 2.0 0.6 0.3 0.1 20.4 0.3 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.3 66.2 46.4 57.8 43.7 49.2 58.0 63.5 54.0 50.8 58.3 57.9 109.3 3.2 25.7 33.3 0.5 0.0 6.8 0.0 5.2 21.1 15.1 13.0 7.9 10.0 2.5 5.5 0.0 0.5 0.9 0.4 3.9 5.8 2.8 4.4 41.1 69.6 1.2 2.7 3.1 4.4 0.4 40.5 2.0 14.5 0.0 7.7 93.1 37.5 2.4 30.3 7.8 3.9 0.0 4.4 0.0 7.2 141.7 2.9 0.0 31.9 0.1 29.6 0.0 46.3 35.6 2.4 9.0 114.0 1.8 4.5 2.1 2.6 1.5 11.3 151.2 51.3 64.7 4.2 4.4 1.3 0.0 0.8 1.4 2.6 1.8 2.1 TOX2 "C20orf100, dJ1108D11.2, GCX-1" ENSG00000124191 "TOX high mobility group box family member 2" Q96NM4 20 43914852-44069616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 50.2" "Cell type enhanced" "Detected in many" "Early spermatids: 22.3;Excitatory neurons: 20.5;Hepatic stellate cells: 34.2;Inhibitory neurons: 76.9;Oligodendrocyte precursor cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 92.0;U-266/70: 57.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049900, HPA058396" Approved Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049900: AB_2680942, HPA058396: AB_2683704" "unprognostic (2.15e-2)" "unprognostic (1.82e-2)" "unprognostic (8.97e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (7.53e-3)" "unprognostic (6.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (7.45e-8)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (7.60e-2)" "unprognostic (3.12e-1)" 10.0 4.0 11.2 6.2 8.2 1.8 6.8 4.9 18.4 10.2 2.3 7.6 1.3 6.2 1.1 12.8 3.6 2.9 3.6 8.3 35.7 5.1 5.2 36.4 13.3 12.3 18.8 3.1 2.0 10.1 24.6 2.6 15.9 16.7 2.4 1.9 3.8 2.7 1.5 5.1 10.2 1.6 5.8 5.7 9.7 20.8 25.9 50.2 7.4 6.4 8.1 17.6 8.9 10.6 9.9 12.5 4.9 0.9 4.7 13.3 0.1 11.5 5.3 8.1 8.9 0.0 4.0 0.0 16.8 16.6 35.2 5.1 3.2 0.3 8.4 15.5 2.7 0.0 1.1 0.0 92.0 0.1 19.4 31.0 14.0 27.0 1.6 25.8 9.4 9.5 0.0 14.5 4.6 11.3 3.2 4.5 3.0 0.3 42.2 0.0 10.1 15.4 0.0 1.2 4.3 35.8 2.4 0.0 18.0 0.5 0.0 9.2 11.3 0.0 7.5 0.3 0.1 57.4 13.5 9.0 16.9 0.1 27.0 0.0 0.2 6.5 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.7 1.1 0.0 2.6 1.2 0.1 11.2 8.2 4.9 18.4 8.3 35.7 12.3 18.8 15.9 5.8 25.9 10.6 8.0 0.0 0.6 3.9 3.4 1.0 1.0 0.7 0.0 0.8 0.2 0.1 0.8 1.5 0.1 0.0 0.0 0.0 7.3 0.3 0.0 0.1 22.3 0.3 8.9 8.9 0.0 0.0 20.5 0.2 0.1 6.7 1.5 0.3 0.0 10.7 34.2 0.5 1.5 3.3 76.9 0.6 0.0 2.9 3.6 17.3 1.8 1.2 1.8 3.7 0.2 4.6 1.0 45.2 0.5 0.1 2.2 0.7 12.1 0.5 0.0 0.1 0.0 0.1 0.0 0.4 8.7 1.3 1.8 0.2 1.3 0.3 10.5 0.1 1.8 0.3 TOX3 "CAGF9, TNRC9" ENSG00000103460 "TOX high mobility group box family member 3" O15405 16 52436417-52547802 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.9;retina: 17.6;stomach 1: 20.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 52.9;Enteroendocrine cells: 61.7;Inhibitory neurons: 138.9;Muller glia cells: 162.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 75.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 46.1;HAP1: 22.1;Hep G2: 20.8;OE19: 25.8;RT4: 97.1;SCLC-21H: 30.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040240, HPA040376" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm Cytosol "HPA040240: , HPA040376: AB_10795522" "unprognostic (1.14e-2)" "unprognostic (9.75e-3)" "unprognostic (9.08e-3)" "unprognostic (3.32e-2)" "unprognostic (3.50e-1)" "unprognostic (2.31e-1)" "unprognostic (4.74e-3)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.94e-2)" "unprognostic (2.59e-1)" "unprognostic (4.60e-3)" "prognostic favorable (3.08e-12)" "unprognostic (1.19e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.95e-4)" 0.4 3.0 4.7 1.4 5.6 0.0 3.8 1.2 6.0 7.6 0.3 15.6 9.3 1.3 4.4 0.6 3.1 6.9 0.0 5.3 4.4 9.5 5.2 1.4 0.1 4.6 3.5 0.9 2.6 0.0 2.3 0.2 3.0 1.8 17.9 17.6 8.9 0.5 4.0 0.7 9.3 1.0 5.1 0.0 20.3 0.6 8.4 1.3 0.0 0.5 0.2 5.7 1.0 6.8 0.0 5.8 46.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 3.5 0.0 0.3 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 25.8 0.0 0.0 8.0 0.2 10.7 97.1 30.0 0.0 0.0 0.3 0.0 2.3 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 5.6 1.2 6.0 5.3 4.4 4.6 3.5 3.0 5.1 8.4 6.8 0.2 6.4 8.2 1.3 0.0 1.0 0.5 2.8 0.6 4.1 20.0 12.6 0.7 52.9 7.7 35.0 0.0 0.0 0.0 47.6 3.9 1.6 3.2 1.6 0.4 0.3 61.7 0.0 3.9 5.1 0.0 1.5 29.6 6.1 0.0 0.1 0.7 4.6 0.1 40.4 138.9 31.7 2.0 0.0 0.3 1.8 0.6 0.2 0.0 8.4 0.0 162.1 0.0 51.8 75.0 15.3 15.2 0.0 0.2 11.8 16.6 14.0 12.3 3.8 0.0 3.3 0.8 0.1 0.8 0.3 0.3 0.0 0.4 9.7 32.6 6.5 TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 2111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" 324.1 109.9 24.7 186.3 26.3 33.8 269.0 42.1 40.4 342.4 23.4 255.0 64.6 455.0 10.6 401.8 310.0 144.8 189.6 23.2 27.0 168.1 54.1 374.1 78.2 30.7 28.7 293.8 77.9 23.6 93.4 170.7 31.9 212.1 39.2 3.6 267.2 140.4 50.3 241.4 153.8 190.4 29.1 244.1 201.4 66.2 36.6 32.4 119.4 19.3 68.5 287.5 333.8 27.8 614.5 275.2 194.7 190.9 701.3 728.2 725.6 1082.9 470.3 356.4 357.7 325.5 473.5 31.1 724.2 492.9 383.9 331.6 72.9 386.7 141.6 503.8 138.8 305.4 270.2 232.3 357.0 52.3 728.3 715.2 94.0 327.6 331.1 353.2 427.2 115.7 46.2 217.9 360.8 290.2 152.4 233.0 227.1 461.2 380.4 201.4 413.2 143.4 87.3 387.9 75.3 315.3 670.4 155.5 298.8 90.6 5.3 60.8 1237.2 954.1 166.8 2111.0 875.3 82.4 167.3 142.5 651.4 144.5 337.0 130.8 81.4 5.9 96.0 93.9 71.4 59.6 69.0 84.3 96.6 53.0 18.6 47.2 82.1 75.2 50.4 76.8 151.0 158.4 24.7 26.3 42.1 40.4 23.2 27.0 30.7 28.7 31.9 29.1 36.6 27.8 389.4 400.6 156.6 9.4 148.6 431.1 1297.2 175.2 273.8 45.9 194.3 189.4 49.1 120.1 297.0 242.8 10.4 263.5 205.6 298.4 13.7 717.1 67.3 159.0 506.6 425.5 94.0 33.4 23.8 571.6 852.9 345.1 303.7 305.0 249.6 170.8 288.8 4.2 336.8 5.0 19.0 215.8 101.7 112.0 368.8 54.8 173.1 433.2 142.3 26.2 249.5 7.5 132.8 13.6 48.5 1017.2 258.8 547.2 310.9 900.2 61.2 29.0 133.1 11.7 335.2 170.0 516.6 29.5 10.1 328.2 343.8 568.9 192.0 222.3 162.7 1025.0 TPSG1 "PRSS31, TMT" ENSG00000116176 "Tryptase gamma 1" Q9NRR2 16 1221651-1225257 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 14.7" "Cell type enriched" "Detected in some" 6 "Intestinal goblet cells: 278.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HMC-1: 23.2;MCF7: 7.9" "Not detected" "Not detected" HPA060458 Enhanced NA NA "Cluster 9: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA060458: AB_2684283" "unprognostic (1.86e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-3)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-2)" "unprognostic (9.97e-2)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.76e-8)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (8.65e-4)" "unprognostic (5.70e-2)" 0.7 1.0 0.4 1.4 1.6 0.0 3.2 0.0 0.4 0.7 0.0 14.7 14.1 1.3 0.1 0.8 0.7 1.0 0.3 0.2 0.4 1.2 0.4 0.8 0.0 0.1 0.1 2.1 0.2 0.0 3.1 0.0 0.3 1.1 9.0 0.1 0.3 0.2 0.2 1.2 9.3 0.3 0.1 0.0 1.1 1.6 0.5 0.0 0.1 0.0 0.0 1.8 0.8 0.0 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.6 0.0 0.4 0.2 0.4 0.1 0.1 0.3 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.2 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 0.0 0.0 0.4 0.0 0.0 0.0 278.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.3 0.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 4.7 0.0 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRAV1-2 ENSG00000256553 "T cell receptor alpha variable 1-2" A0A0B4J238 14 21642889-21643578 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 19.3" "Cell type enriched" "Detected in single" 6 "T-cells: 4.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "MAIT T-cell: 2027.8" "Lineage enriched" "Detected in many" 507 "T-cells: 2027.8" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.19e-3)" "unprognostic (1.29e-3)" "unprognostic (1.59e-2)" "unprognostic (1.84e-3)" "unprognostic (5.87e-3)" "unprognostic (1.55e-3)" "unprognostic (3.56e-2)" "unprognostic (8.90e-2)" "unprognostic (6.50e-4)" "unprognostic (3.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.13e-2)" "unprognostic (2.15e-1)" "unprognostic (1.43e-1)" "unprognostic (8.99e-2)" "unprognostic (8.30e-2)" 0.3 0.7 0.0 4.5 0.0 1.3 0.4 0.0 0.4 0.6 0.0 1.2 1.6 0.3 0.3 0.5 0.7 3.1 0.1 0.0 0.0 0.2 1.1 2.0 7.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 1.1 0.0 0.3 0.0 0.0 0.4 1.3 0.3 0.1 4.6 1.5 0.1 0.0 19.3 0.5 0.0 7.2 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 0.7 1.0 0.6 2027.8 0.4 44.9 311.2 0.8 0.2 40.9 70.0 3.9 0.3 1.3 1.7 79.5 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 TRAV12-2 ENSG00000211789 "T cell receptor alpha variable 12-2" A0A075B6T6 14 21887857-21888502 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 22.4" "Cell type enriched" "Detected in some" 6 "T-cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 17 "memory CD4 T-cell: 101.9;memory CD8 T-cell: 87.7;naive CD4 T-cell: 90.3;naive CD8 T-cell: 65.2;T-reg: 143.3" "Lineage enriched" "Detected in many" 77 "T-cells: 143.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.74e-2)" "unprognostic (4.98e-3)" "unprognostic (4.75e-2)" "unprognostic (2.41e-4)" "unprognostic (2.22e-2)" "unprognostic (7.44e-2)" "unprognostic (5.23e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-3)" "unprognostic (3.69e-1)" "unprognostic (3.34e-3)" "unprognostic (9.87e-2)" "unprognostic (3.01e-2)" 0.8 0.8 0.0 7.5 0.0 0.9 1.0 0.0 0.1 1.0 0.0 1.6 4.1 0.8 0.5 0.8 1.2 2.5 0.3 0.0 0.0 0.3 0.6 2.5 15.7 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.8 2.1 0.0 1.7 0.1 0.2 0.5 2.9 0.5 0.0 5.9 2.3 0.0 0.0 22.4 0.6 0.0 13.5 3.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.2 0.0 5.7 0.1 101.9 87.7 0.2 0.1 90.3 65.2 1.8 0.1 0.2 0.1 143.3 27.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV12-3 "TCRAV12S3, TCRAV2S2, TRAV123" ENSG00000211794 "T cell receptor alpha variable 12-3" A0A0B4J271 14 21965451-21966061 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 60.3" "Group enriched" "Detected in some" 4 "Erythroid cells: 1.7;T-cells: 6.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 186.5;T-reg: 256.6" "Lineage enriched" "Detected in many" 23 "T-cells: 256.6" "Cell line enriched" "Detected in single" 43 "JURKAT: 4.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.62e-4)" "unprognostic (7.68e-4)" "unprognostic (5.17e-2)" "unprognostic (1.33e-3)" "unprognostic (2.32e-1)" "unprognostic (1.80e-3)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.55e-4)" "unprognostic (9.00e-3)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (4.52e-5)" "unprognostic (3.75e-1)" "unprognostic (4.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.68e-2)" 0.5 0.1 0.0 9.3 0.0 1.5 1.1 0.0 0.1 1.7 0.0 2.1 2.2 0.6 0.9 0.4 0.6 6.1 0.5 0.0 0.0 0.3 0.4 2.8 18.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 3.2 0.0 0.3 0.2 0.1 0.4 2.7 0.5 0.0 4.6 1.9 0.1 0.0 60.3 0.2 0.0 17.4 3.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.5 0.2 0.4 0.2 12.7 0.4 186.5 57.4 0.4 1.8 119.7 153.3 4.6 0.9 0.7 0.5 256.6 48.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 TRAV13-2 ENSG00000211791 "T cell receptor alpha variable 13-2" A0A0B4J235 14 21918188-21918756 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "lymphoid tissue: 51.7" "Group enriched" "Detected in some" 4 "NK-cells: 4.1;T-cells: 5.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 38 "MAIT T-cell: 32.9;memory CD4 T-cell: 94.0;memory CD8 T-cell: 57.3;naive CD4 T-cell: 101.8;naive CD8 T-cell: 114.1;T-reg: 114.8" "Lineage enriched" "Detected in many" 53 "T-cells: 114.8" "Cell line enriched" "Detected in some" 4 "JURKAT: 6.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.15e-3)" "unprognostic (1.47e-2)" "unprognostic (2.07e-2)" "unprognostic (1.26e-3)" "unprognostic (5.58e-1)" "unprognostic (4.38e-4)" "unprognostic (1.08e-1)" "unprognostic (6.47e-2)" "unprognostic (2.85e-2)" "unprognostic (4.16e-2)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (3.66e-4)" "unprognostic (1.52e-1)" "unprognostic (9.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.77e-2)" 0.3 0.0 0.0 6.6 0.0 1.4 0.9 0.0 0.2 0.4 0.0 1.3 2.1 0.2 1.2 0.7 0.3 1.4 0.2 0.0 0.0 0.2 0.4 1.6 14.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 1.0 0.0 0.5 0.1 0.1 0.5 1.6 0.5 0.1 4.6 1.9 0.2 0.0 51.7 0.2 0.0 10.0 1.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.1 2.2 0.2 32.9 0.4 94.0 57.3 0.1 0.2 101.8 114.1 2.1 0.6 0.2 0.3 114.8 40.6 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 5.7 0.0 0.0 0.0 TRAV16 "TCRAV16S1, TCRAV9S1" ENSG00000211796 "T cell receptor alpha variable 16" A0A0A6YYK6 14 21990496-21990938 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 39.8" "Cell type enhanced" "Detected in some" "Erythroid cells: 1.3;Gastric mucus-secreting cells: 3.1;T-cells: 5.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 48.0;T-reg: 58.0" "Lineage enriched" "Detected in single" 164 "T-cells: 58.0" "Cell line enriched" "Detected in single" 184 "JURKAT: 18.3" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.93e-2)" "unprognostic (1.06e-4)" "unprognostic (6.22e-3)" "unprognostic (3.67e-3)" "unprognostic (1.01e-4)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (2.79e-2)" "unprognostic (6.94e-4)" "unprognostic (5.25e-2)" "unprognostic (2.33e-1)" "unprognostic (5.27e-5)" "unprognostic (1.55e-1)" "unprognostic (3.91e-2)" "unprognostic (4.01e-1)" "unprognostic (2.07e-3)" 0.2 0.0 0.0 5.7 0.0 0.8 0.8 0.0 0.3 0.5 0.0 1.5 1.9 0.2 1.3 0.5 0.2 2.6 0.1 0.0 0.0 0.6 0.2 1.8 16.6 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 1.7 0.0 0.6 0.1 0.0 0.6 1.6 0.0 0.0 2.8 1.7 0.1 0.1 39.8 0.3 0.0 10.1 3.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 11.9 0.0 45.6 18.2 0.0 0.1 48.0 22.4 0.3 0.0 0.0 0.0 58.0 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 TRAV2 ENSG00000211776 "T cell receptor alpha variable 2" A0A0B4J234 14 21712321-21712843 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "lymphoid tissue: 56.3" "Cell type enriched" "Detected in single" 5 "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 40.9" "Lineage enriched" "Detected in single" 124 "T-cells: 40.9" "Cell line enriched" "Detected in single" 21 "Daudi: 2.1" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.38e-2)" "unprognostic (6.44e-3)" "unprognostic (7.50e-2)" "unprognostic (1.93e-2)" "unprognostic (1.86e-3)" "unprognostic (3.64e-2)" "unprognostic (4.45e-2)" "unprognostic (2.00e-2)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (5.84e-2)" "unprognostic (9.93e-5)" "unprognostic (1.92e-1)" "unprognostic (4.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.45e-2)" 0.4 0.2 0.0 8.2 0.0 2.5 0.3 0.0 0.5 0.3 0.0 2.0 0.8 0.0 0.0 0.9 0.3 0.9 0.3 0.0 0.0 0.2 0.3 1.6 19.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.8 0.0 0.2 0.0 0.0 0.1 1.7 0.0 0.0 3.3 2.7 0.2 0.0 56.3 0.2 0.0 13.2 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 31.3 0.0 31.5 9.9 0.0 0.0 24.5 9.6 0.1 0.0 0.0 0.3 40.9 5.7 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRAV21 ENSG00000211801 "T cell receptor alpha variable 21" A0A0B4J279 14 22052514-22053056 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "lymphoid tissue: 63.2" "Group enriched" "Detected in some" 12 "Gastric mucus-secreting cells: 6.1;T-cells: 23.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 220.5;memory CD8 T-cell: 233.5;naive CD4 T-cell: 198.6;naive CD8 T-cell: 204.8;T-reg: 391.9" "Lineage enriched" "Detected in many" 76 "T-cells: 391.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.53e-4)" "unprognostic (1.03e-2)" "unprognostic (3.94e-3)" "unprognostic (3.69e-4)" "unprognostic (1.74e-1)" "unprognostic (1.22e-3)" "unprognostic (4.86e-3)" "unprognostic (2.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" "unprognostic (4.20e-2)" "unprognostic (9.80e-2)" "unprognostic (4.53e-3)" "unprognostic (3.13e-1)" "unprognostic (2.96e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" 0.4 0.1 0.0 5.9 0.0 0.8 1.4 0.0 0.1 1.1 0.0 1.8 2.0 0.1 1.7 0.9 0.7 1.7 0.1 0.0 0.1 0.7 0.5 2.7 14.2 0.2 0.0 0.4 0.0 0.1 0.0 0.3 0.1 0.7 2.7 0.0 1.0 0.1 0.4 0.3 2.6 0.7 0.1 5.4 2.4 0.1 0.0 63.2 3.8 0.0 17.0 2.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.9 1.7 0.2 17.4 0.5 220.5 233.5 0.9 0.8 198.6 204.8 5.1 0.4 0.7 0.6 391.9 73.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.0 0.0 0.0 0.0 TRAV23DV6 "TCRAV17S1, TRAV23/DV6" ENSG00000211803 "T cell receptor alpha variable 23/delta variable 6" A0A075B6W5 14 22086407-22086961 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lymphoid tissue: 26.3" "Cell type enriched" "Detected in single" 20 "T-cells: 4.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 79.3;naive CD4 T-cell: 85.6;T-reg: 65.6" "Lineage enriched" "Detected in many" 56 "T-cells: 85.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.79e-3)" "unprognostic (2.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.69e-1)" "unprognostic (2.66e-2)" "unprognostic (2.20e-2)" "unprognostic (1.19e-3)" "unprognostic (3.91e-2)" "unprognostic (1.04e-2)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (4.56e-3)" "unprognostic (1.34e-1)" "unprognostic (4.47e-2)" "unprognostic (7.44e-2)" "unprognostic (1.33e-1)" 0.5 0.1 0.0 6.4 0.0 1.1 0.5 0.0 0.0 0.5 0.0 1.2 2.1 0.2 0.0 1.0 0.5 1.3 0.3 0.0 0.0 0.1 0.5 1.8 10.3 0.0 0.1 1.3 0.0 0.1 0.0 0.0 0.0 0.6 1.8 0.0 0.5 0.1 0.1 0.1 1.0 0.5 0.0 3.3 2.2 0.0 0.0 26.3 0.6 0.0 10.8 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 2.0 0.0 3.2 0.0 79.3 19.6 0.0 0.1 85.6 21.4 1.5 0.1 0.0 0.0 65.6 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 TRAV25 "TCRAV25S1, TCRAV32S1" ENSG00000211806 "T cell receptor alpha variable 25" A0A0B4J276 14 22112347-22113031 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 15.2" "Cell type enriched" "Detected in single" 6 "T-cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 63 "memory CD4 T-cell: 33.5;memory CD8 T-cell: 20.9;naive CD4 T-cell: 32.6;naive CD8 T-cell: 22.5;T-reg: 49.4" "Lineage enriched" "Detected in single" 404 "T-cells: 49.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.50e-3)" "unprognostic (1.49e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-5)" "unprognostic (6.65e-3)" "unprognostic (7.53e-3)" "unprognostic (7.30e-3)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (9.55e-2)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (3.74e-1)" 0.1 0.0 0.0 2.7 0.1 0.3 0.5 0.0 0.2 0.1 0.0 0.8 0.8 0.3 0.6 0.2 0.2 0.5 0.0 0.0 0.1 0.2 0.1 1.5 8.7 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.2 0.1 0.7 0.3 0.0 2.3 1.7 0.0 0.1 15.2 0.1 0.0 7.7 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 33.5 20.9 0.0 0.0 32.6 22.5 0.1 0.0 0.0 0.0 49.4 7.4 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 TRAV3 ENSG00000211777 "T cell receptor alpha variable 3" A0A0B4J244 14 21723713-21724321 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 10.1" "Cell type enriched" "Detected in some" 4 "T-cells: 6.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 48.8;memory CD8 T-cell: 33.6;naive CD4 T-cell: 51.2;naive CD8 T-cell: 47.8;T-reg: 112.7" "Lineage enriched" "Detected in single" 144 "T-cells: 112.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.32e-3)" "unprognostic (4.61e-4)" "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (7.75e-2)" "unprognostic (8.35e-4)" "unprognostic (8.65e-3)" "unprognostic (4.31e-3)" "unprognostic (2.88e-3)" "unprognostic (4.24e-3)" "unprognostic (5.27e-2)" "unprognostic (3.35e-1)" "unprognostic (1.91e-4)" "unprognostic (1.67e-1)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" 0.2 0.2 0.0 2.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.5 0.1 0.2 0.6 0.5 0.0 0.0 0.1 0.2 0.8 7.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.8 0.0 0.2 0.0 0.0 0.3 1.3 0.0 0.0 2.0 1.0 0.3 0.4 10.1 0.1 0.1 5.7 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 14.3 0.0 48.8 33.6 0.1 0.1 51.2 47.8 0.7 0.1 0.0 0.0 112.7 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 TRAV4 "TCRAV20S1, TCRAV4S1" ENSG00000211778 "T cell receptor alpha variable 4" A0A0B4J268 14 21736152-21736982 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 37.9" "Cell type enriched" "Detected in some" 8 "T-cells: 8.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 66.1;memory CD4 T-cell: 81.9;memory CD8 T-cell: 124.0;naive CD4 T-cell: 77.1;naive CD8 T-cell: 81.0;T-reg: 167.9" "Lineage enriched" "Detected in many" 118 "T-cells: 167.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.13e-2)" "unprognostic (4.08e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-4)" "unprognostic (5.20e-3)" "unprognostic (1.18e-4)" "unprognostic (1.34e-2)" "unprognostic (5.48e-2)" "unprognostic (7.19e-3)" "unprognostic (2.48e-3)" "unprognostic (8.68e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-4)" "unprognostic (1.65e-1)" "unprognostic (3.23e-1)" "unprognostic (2.89e-1)" "unprognostic (6.49e-2)" 0.4 0.3 0.0 7.7 0.0 1.3 1.1 0.0 0.4 1.1 0.0 1.8 1.7 0.3 0.0 1.1 0.6 2.8 0.5 0.1 0.0 0.2 0.6 2.4 17.4 0.3 0.4 0.2 0.5 0.1 0.0 0.1 0.2 1.2 2.1 0.0 0.8 0.1 0.0 0.4 3.3 0.4 0.1 5.4 2.4 0.3 0.2 37.9 0.3 0.0 14.2 2.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.6 0.1 66.1 0.1 81.9 124.0 0.1 0.1 77.1 81.0 1.4 0.4 0.5 0.4 167.9 25.2 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 TRAV5 ENSG00000211779 "T cell receptor alpha variable 5" A0A0B4J249 14 21749178-21749705 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 12.9" "Cell type enriched" "Detected in some" 5 "T-cells: 7.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 52 "MAIT T-cell: 24.7;memory CD4 T-cell: 49.5;memory CD8 T-cell: 77.3;naive CD4 T-cell: 39.9;naive CD8 T-cell: 74.0;T-reg: 81.4" "Lineage enriched" "Detected in many" 73 "T-cells: 81.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.04e-3)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.69e-2)" "unprognostic (6.26e-5)" "unprognostic (3.58e-1)" "unprognostic (8.15e-2)" "unprognostic (5.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (3.11e-2)" "unprognostic (8.38e-6)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" "unprognostic (1.78e-1)" "unprognostic (1.70e-2)" 0.1 0.4 0.0 3.6 0.0 0.5 0.7 0.0 0.2 0.3 0.5 1.0 0.5 0.7 0.0 0.3 0.1 2.7 0.2 0.1 0.0 0.2 0.8 1.1 12.9 0.3 0.2 0.3 0.6 0.0 0.0 0.0 0.1 2.1 1.6 0.0 2.6 0.3 0.0 0.0 2.7 0.8 0.0 4.6 1.8 0.1 0.1 11.5 0.8 0.8 7.6 0.7 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.0 0.5 24.7 0.2 49.5 77.3 0.1 0.1 39.9 74.0 1.1 0.0 0.2 0.3 81.4 17.9 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.7 0.0 0.0 0.0 TRAV6 TCRAV5S1 ENSG00000211780 "T cell receptor alpha variable 6" A0A075B6T7 14 21768489-21769080 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.2" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 1.1;T-cells: 3.4" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 70 "MAIT T-cell: 17.1;memory CD4 T-cell: 33.7;memory CD8 T-cell: 19.0;naive CD4 T-cell: 26.3;naive CD8 T-cell: 16.2;T-reg: 59.6" "Lineage enriched" "Detected in single" 146 "T-cells: 59.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.78e-1)" "unprognostic (3.49e-4)" "unprognostic (3.25e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (8.90e-3)" "unprognostic (2.05e-1)" "unprognostic (1.81e-1)" "unprognostic (2.87e-5)" "unprognostic (1.32e-1)" "unprognostic (2.95e-2)" "unprognostic (3.59e-1)" "unprognostic (1.24e-2)" 0.1 0.0 0.0 2.4 0.0 0.6 0.5 0.0 0.0 0.1 0.0 1.0 0.3 0.1 0.6 0.6 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.8 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.2 0.2 0.0 0.0 2.3 0.0 0.0 2.7 0.8 0.1 0.4 11.2 0.1 0.0 4.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 17.1 0.2 33.7 19.0 0.0 0.1 26.3 16.2 0.4 0.0 0.0 0.0 59.6 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 TRAV8-1 ENSG00000211782 "T cell receptor alpha variable 8-1" A0A0A6YYK1 14 21797287-21797886 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 11.8" "Cell type enriched" "Detected in single" 9 "T-cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 43 "MAIT T-cell: 14.2;memory CD4 T-cell: 39.5;memory CD8 T-cell: 20.6;naive CD4 T-cell: 37.6;naive CD8 T-cell: 16.3;T-reg: 54.4" "Lineage enriched" "Detected in single" 77 "T-cells: 54.4" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (8.53e-3)" "unprognostic (1.98e-2)" "unprognostic (5.44e-2)" "unprognostic (1.34e-2)" "unprognostic (4.86e-4)" "unprognostic (2.84e-3)" "unprognostic (8.19e-3)" "unprognostic (1.90e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (2.60e-1)" "unprognostic (2.31e-1)" "unprognostic (3.86e-1)" "unprognostic (5.72e-2)" 0.1 0.0 0.0 3.7 0.0 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.6 0.2 0.2 0.7 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.8 6.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.7 0.0 0.0 1.7 0.5 0.2 0.0 11.8 0.0 0.0 4.7 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 14.2 0.0 39.5 20.6 0.1 0.1 37.6 16.3 0.7 0.0 0.0 0.1 54.4 8.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 TRAV9-2 ENSG00000211793 "T cell receptor alpha variable 9-2" A0A087WT02 14 21941128-21941657 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "lymphoid tissue: 27.8" "Cell type enriched" "Detected in single" 6 "T-cells: 5.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 178.3;naive CD4 T-cell: 172.2;T-reg: 350.8" "Lineage enriched" "Detected in many" 78 "T-cells: 350.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-3)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (1.25e-4)" "unprognostic (1.14e-5)" "unprognostic (1.37e-2)" "unprognostic (2.23e-2)" "unprognostic (5.98e-4)" "unprognostic (9.53e-3)" "unprognostic (1.92e-1)" "unprognostic (2.51e-1)" "unprognostic (9.00e-4)" "unprognostic (2.49e-1)" "unprognostic (4.28e-2)" "unprognostic (3.38e-1)" "unprognostic (2.56e-2)" 0.2 0.0 0.0 5.6 0.0 0.1 0.3 0.0 0.2 0.7 0.0 1.8 0.8 0.2 0.0 0.4 0.4 1.7 0.2 0.0 0.0 0.2 1.1 1.8 18.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 0.0 0.1 0.4 0.2 0.2 2.0 0.5 0.0 5.0 3.1 0.1 0.0 27.8 0.2 0.2 16.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.8 0.0 14.3 0.6 178.3 43.4 0.2 0.3 172.2 42.5 4.4 0.3 0.2 1.1 350.8 40.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 TRBJ1-1 "TCRBJ1S1, TRBJ11" ENSG00000282320 "T cell receptor beta joining 1-1" A0A0J9YXA8 7 142786880-142786927 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 83.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 1111.5" "Lineage enriched" "Detected in all" 18 "T-cells: 1111.5" "Cell line enhanced" "Detected in some" "Daudi: 1.2;K-562: 1.2;U-266/84: 4.4;U-698: 1.0" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 58: T-cells - T-cell receptor" 2.1 0.0 0.6 33.1 0.4 7.8 0.8 0.0 0.8 1.0 0.0 4.6 5.9 1.6 0.0 2.8 0.9 4.2 0.4 0.2 0.1 0.3 6.1 5.6 44.8 0.3 0.2 1.6 3.0 0.0 0.0 0.5 0.3 1.6 7.9 0.3 1.4 0.5 3.4 0.0 6.1 0.6 0.2 18.6 9.8 0.3 0.6 83.9 0.1 5.5 48.6 2.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 1.0 0.0 0.0 0.0 46.7 1.3 2.9 163.0 0.9 240.7 5.8 622.5 480.8 1.9 1.9 690.1 869.6 16.2 62.1 1.5 4.7 1111.5 312.7 0.6 0.4 0.0 0.8 0.2 0.1 0.3 0.2 0.3 0.2 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRBJ2-5 "TCRBJ2S5, TRBJ25" ENSG00000211769 "T cell receptor beta joining 2-5" 7 142797119-142797166 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 2.7;intestine: 4.5;lymphoid tissue: 10.9;stomach 1: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 1102.2" "Lineage enriched" "Detected in all" 14 "T-cells: 1102.2" "Cell line enriched" "Detected in some" 7 "MOLT-4: 152.3" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.0 0.0 0.2 9.0 0.9 2.7 0.0 0.2 1.0 0.0 0.0 0.9 4.5 0.0 0.0 0.4 0.0 0.6 0.0 0.7 0.3 0.0 0.5 1.1 9.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 10.9 7.6 0.4 0.8 9.6 0.0 0.0 6.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 152.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 2.4 0.0 0.8 1.0 0.0 21.7 0.0 0.0 0.0 2.4 1.3 3.0 103.7 0.9 271.0 47.0 586.4 389.5 1.8 81.6 664.4 355.4 12.4 36.3 2.9 3.4 1102.2 282.2 0.2 0.9 0.2 1.0 0.7 0.3 0.5 0.2 0.4 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TRBV15 "TCRBV15S1, TCRBV24S1A3T" ENSG00000276819 "T cell receptor beta variable 15" 7 142592928-142593473 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "lymphoid tissue: 46.9" "Cell type enriched" "Detected in single" 27 "T-cells: 2.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in many" 48 "MAIT T-cell: 21.9;memory CD4 T-cell: 14.6;memory CD8 T-cell: 21.1;naive CD4 T-cell: 18.8;naive CD8 T-cell: 12.3;T-reg: 27.8" "Lineage enriched" "Detected in single" 158 "T-cells: 27.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.07e-2)" "unprognostic (1.03e-3)" "unprognostic (1.89e-3)" "unprognostic (1.39e-3)" "unprognostic (2.09e-4)" "unprognostic (1.08e-2)" "unprognostic (6.75e-2)" "unprognostic (5.47e-3)" "unprognostic (7.77e-2)" "unprognostic (4.14e-2)" "unprognostic (3.86e-1)" "unprognostic (2.52e-3)" "unprognostic (2.38e-1)" "unprognostic (8.34e-2)" "unprognostic (3.23e-1)" "unprognostic (2.55e-2)" 0.1 0.1 0.0 1.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.4 0.1 0.0 46.9 0.1 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 21.9 0.0 14.6 21.1 0.0 0.0 18.8 12.3 0.1 0.0 0.0 0.0 27.8 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 TRBV18 TCRBV18S1 ENSG00000276557 "T cell receptor beta variable 18" A0A087X0M5 7 142615716-142616415 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "lymphoid tissue: 27.5" "Cell type enriched" "Detected in single" 13 "T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 102.0" "Lineage enriched" "Detected in single" 316 "T-cells: 102.0" "Not detected" "Not detected" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.55e-2)" "unprognostic (1.14e-3)" "unprognostic (4.53e-3)" "unprognostic (7.74e-4)" "unprognostic (2.60e-2)" "unprognostic (1.08e-4)" "unprognostic (3.11e-1)" "unprognostic (6.76e-3)" "unprognostic (3.67e-2)" "unprognostic (7.81e-4)" "unprognostic (1.41e-1)" "unprognostic (1.72e-1)" "unprognostic (3.28e-6)" "unprognostic (3.80e-1)" "unprognostic (4.42e-2)" "unprognostic (4.02e-2)" "unprognostic (2.47e-2)" 0.2 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.1 0.8 8.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.3 1.6 0.2 0.0 1.7 0.5 0.0 0.0 27.5 0.2 0.0 2.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 3.0 0.2 46.6 10.8 0.0 0.0 49.3 16.9 0.2 0.1 0.1 0.0 102.0 14.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV23-1 "TCRBV19S1P, TCRBV23S1, TRBV231" ENSG00000211749 "T cell receptor beta variable 23-1 (non-functional)" 7 142645961-142646467 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.02e-5)" "unprognostic (7.32e-4)" "unprognostic (1.71e-4)" "unprognostic (1.34e-3)" "unprognostic (6.71e-3)" "unprognostic (1.28e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-6)" "unprognostic (1.14e-1)" "unprognostic (5.86e-3)" "unprognostic (1.37e-1)" 0.3 0.0 0.0 3.4 0.1 2.2 0.1 0.1 0.1 0.2 0.0 0.4 0.3 0.1 0.6 0.1 0.2 1.0 0.3 0.0 0.0 0.2 0.2 0.7 8.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.4 0.0 0.2 0.1 2.0 0.1 0.0 2.2 0.2 0.0 0.0 11.7 0.3 0.1 5.9 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.9 0.5 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.1 1.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 TRBV24-1 "TCRBV15S1, TCRBV24S1, TRBV241" ENSG00000211750 "T cell receptor beta variable 24-1" A0A075B6N3 7 142656701-142657213 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.7;lymphoid tissue: 6.7" "Cell type enriched" "Detected in single" 23 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "basal ganglia: 2.7" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 26.6" "Lineage enriched" "Detected in single" 129 "T-cells: 26.6" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.42e-2)" "unprognostic (1.64e-5)" "unprognostic (1.59e-1)" "unprognostic (9.71e-3)" "unprognostic (3.82e-1)" "unprognostic (9.30e-2)" "unprognostic (3.08e-2)" "unprognostic (1.81e-1)" "unprognostic (6.73e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-7)" "unprognostic (2.36e-1)" "unprognostic (5.80e-2)" "unprognostic (7.76e-3)" "unprognostic (4.39e-2)" 0.2 0.0 0.1 0.0 2.7 0.2 0.0 0.0 0.5 0.3 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.4 2.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 1.0 0.0 0.9 0.2 0.0 1.3 1.6 0.4 0.5 6.7 0.1 0.0 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 9.0 0.0 5.7 0.0 15.4 15.5 0.0 0.0 11.4 26.6 0.2 0.0 0.0 0.0 23.2 4.6 0.1 2.7 0.0 0.5 0.2 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 TRBV3-1 "TCRBV3S1, TCRBV9S1A1T, TRBV31" ENSG00000237702 "T cell receptor beta variable 3-1" A0A576 7 142308542-142309048 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 22 "lymphoid tissue: 51.1" "Group enriched" "Detected in some" 22 "Plasma cells: 10.1;T-cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory CD4 T-cell: 52.4;memory CD8 T-cell: 45.9;naive CD4 T-cell: 71.6;naive CD8 T-cell: 117.4;T-reg: 99.6" "Lineage enriched" "Detected in many" 32 "T-cells: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (7.98e-5)" "unprognostic (2.38e-3)" "unprognostic (5.19e-3)" "unprognostic (2.46e-2)" "unprognostic (1.19e-2)" "unprognostic (6.19e-4)" "unprognostic (1.46e-2)" "unprognostic (5.42e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-1)" "unprognostic (2.01e-4)" "unprognostic (1.75e-1)" "unprognostic (1.13e-3)" "unprognostic (1.53e-2)" "unprognostic (1.26e-2)" 0.4 0.0 0.0 5.3 0.0 1.9 0.4 0.0 0.1 0.3 0.0 0.9 0.5 0.3 0.1 0.3 0.3 1.2 0.2 0.0 0.0 0.1 0.2 0.8 10.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 1.0 0.0 0.8 0.2 0.0 0.2 2.2 0.2 0.0 2.7 1.0 0.0 0.0 51.1 0.3 0.1 10.4 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.1 0.3 1.8 0.1 16.6 0.2 52.4 45.9 0.1 0.1 71.6 117.4 2.0 0.4 0.1 0.4 99.6 29.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 TRBV4-1 "BV07S1J2.7, TCRBV4S1, TCRBV7S1A1N2T, TRBV41" ENSG00000211710 "T cell receptor beta variable 4-1" A0A577 7 142313184-142313666 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 115.0" "Cell type enriched" "Detected in some" 7 "T-cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 176.7" "Lineage enriched" "Detected in many" 89 "T-cells: 176.7" "Cell line enriched" "Detected in single" 8 "U-266/84: 1.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.58e-4)" "unprognostic (3.14e-3)" "unprognostic (1.49e-2)" "unprognostic (5.74e-4)" "unprognostic (1.88e-1)" "unprognostic (6.43e-3)" "unprognostic (5.89e-2)" "unprognostic (2.96e-2)" "unprognostic (6.43e-3)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (2.79e-2)" "unprognostic (6.71e-5)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.67e-2)" "unprognostic (8.99e-2)" 0.5 0.0 0.0 7.1 0.1 2.6 0.7 0.0 0.2 0.8 0.0 0.8 0.1 0.2 0.7 1.1 0.9 0.8 0.1 0.0 0.0 0.4 0.4 0.7 15.3 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.8 0.0 0.2 0.0 0.1 0.2 4.3 0.4 0.1 4.1 2.3 0.1 0.0 115.0 0.3 0.0 10.0 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 2.5 0.1 40.2 0.1 69.8 167.3 0.0 0.2 152.1 152.7 1.9 0.8 0.4 0.8 176.7 43.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 TRBV4-2 "TCRBV4S2, TCRBV7S3A2T, TRBV42" ENSG00000211745 "T cell receptor beta variable 4-2" A0A539 7 142345421-142345985 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 21.0" "Cell type enriched" "Detected in some" 8 "T-cells: 23.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 100.2" "Lineage enriched" "Detected in single" 293 "T-cells: 100.2" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.89e-3)" "unprognostic (4.65e-4)" "unprognostic (1.28e-3)" "unprognostic (1.06e-2)" "unprognostic (4.60e-2)" "unprognostic (7.05e-4)" "unprognostic (2.11e-1)" "unprognostic (1.67e-2)" "unprognostic (1.19e-3)" "unprognostic (1.32e-2)" "unprognostic (6.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.82e-4)" "unprognostic (5.50e-2)" "unprognostic (5.99e-2)" "unprognostic (2.16e-1)" "unprognostic (1.48e-2)" 0.2 0.0 0.0 1.4 0.0 0.6 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.4 5.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.3 0.5 0.0 21.0 0.3 0.0 4.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 100.2 0.0 25.6 27.8 0.1 0.0 23.9 14.4 0.1 0.0 0.2 0.3 44.8 8.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 23.9 0.0 0.0 0.0 TRBV5-1 "TCRBV5S1, TCRBV5S1A1T, TRBV51" ENSG00000211734 "T cell receptor beta variable 5-1" A0A578 7 142320677-142321544 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 44.0" "Cell type enriched" "Detected in some" 11 "T-cells: 13.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 211.6;T-reg: 295.5" "Lineage enriched" "Detected in many" 111 "T-cells: 295.5" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (2.26e-4)" "unprognostic (1.36e-3)" "unprognostic (2.59e-2)" "unprognostic (1.49e-3)" "unprognostic (6.65e-2)" "unprognostic (7.02e-5)" "unprognostic (2.55e-2)" "unprognostic (3.66e-2)" "unprognostic (4.29e-3)" "unprognostic (5.85e-4)" "unprognostic (3.55e-2)" "unprognostic (4.36e-1)" "unprognostic (5.96e-7)" "unprognostic (2.63e-1)" "unprognostic (2.52e-2)" "unprognostic (4.06e-2)" "unprognostic (2.97e-2)" 0.3 0.0 0.0 4.8 0.0 1.1 0.2 0.0 0.0 0.4 0.0 0.7 1.0 0.1 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.2 0.7 9.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.3 1.9 0.1 0.0 2.6 1.6 0.2 0.0 44.0 0.2 0.0 8.9 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 2.6 0.2 11.0 0.4 166.1 65.4 0.4 0.4 211.6 128.7 2.6 0.5 0.5 0.3 295.5 82.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 TRBV5-4 "TCRBV5S4, TCRBV5S6A3N2T, TRBV54" ENSG00000230099 "T cell receptor beta variable 5-4" A0A0C4DH59 7 142462916-142463581 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "lymphoid tissue: 22.1;pancreas: 11.6" "Group enriched" "Detected in some" 9 "Plasma cells: 6.1;T-cells: 6.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 115.7" "Lineage enriched" "Detected in many" 115 "T-cells: 115.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 11.1" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.48e-3)" "unprognostic (6.75e-4)" "unprognostic (1.60e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-3)" "unprognostic (5.82e-2)" "unprognostic (2.79e-2)" "unprognostic (1.59e-2)" "unprognostic (4.88e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-4)" "unprognostic (2.77e-1)" "unprognostic (4.95e-2)" "unprognostic (4.78e-3)" "unprognostic (1.64e-2)" 0.2 0.1 0.0 2.4 0.2 1.2 0.1 0.0 0.0 0.2 0.0 0.7 0.8 0.0 0.1 0.3 0.1 0.5 0.3 0.0 0.0 0.1 0.2 0.4 8.2 0.2 0.0 0.0 11.6 0.0 0.0 0.0 0.2 0.2 1.0 0.7 0.5 0.0 0.2 0.3 1.1 0.0 0.0 2.2 1.0 0.2 0.0 22.1 0.2 0.0 8.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 2.3 0.0 0.0 0.5 0.0 0.2 0.2 0.0 1.3 0.1 2.1 0.0 49.7 26.7 0.0 0.1 62.8 36.4 1.0 0.1 0.1 0.1 115.7 18.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 TRBV5-6 "TCRBV5S2, TCRBV5S6, TRBV56" ENSG00000211728 "T cell receptor beta variable 5-6" A0A599 7 142500028-142500534 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "lymphoid tissue: 33.8" "Group enriched" "Detected in some" 21 "Early spermatids: 13.5;Late spermatids: 14.6;T-cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory CD4 T-cell: 40.2;memory CD8 T-cell: 22.9;naive CD4 T-cell: 35.9;naive CD8 T-cell: 45.2;T-reg: 66.0" "Lineage enriched" "Detected in many" 56 "T-cells: 66.0" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.27e-3)" "unprognostic (8.46e-3)" "unprognostic (1.20e-1)" "unprognostic (7.21e-2)" "unprognostic (5.25e-1)" "unprognostic (3.45e-4)" "unprognostic (5.72e-2)" "unprognostic (6.24e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-3)" "unprognostic (2.64e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-7)" "unprognostic (7.62e-2)" "unprognostic (3.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" 0.2 0.0 0.0 2.1 0.0 0.7 0.3 0.0 0.1 0.5 0.0 0.6 0.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.8 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.2 1.1 0.1 0.0 1.9 0.4 1.7 0.0 33.8 0.1 0.1 5.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.9 0.0 3.0 0.1 40.2 22.9 0.1 0.1 35.9 45.2 1.1 0.0 0.1 0.2 66.0 17.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 TRBV6-2 "TCRBV13S2A1T, TCRBV6S2, TRBV62" ENSG00000283063 "T cell receptor beta variable 6-2" "A0A0J9YXY3, P0DPF7" 7 142349152-142349664 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 8.2" "Cell type enriched" "Detected in single" 10 "T-cells: 6.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 92.1" "Lineage enriched" "Detected in single" 175 "T-cells: 92.1" "Not detected" "Not detected" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.2 0.0 0.0 2.4 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.5 8.2 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 2.3 0.2 0.0 0.0 4.6 0.3 0.0 5.8 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 92.1 0.2 24.0 26.4 0.0 0.0 21.7 17.5 0.5 0.0 0.1 0.1 40.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 TRBV6-6 "TCRBV13S6A2T, TCRBV6S6, TRBV66" ENSG00000211724 "T cell receptor beta variable 6-6" A0A0A6YYG2 7 142469537-142470013 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 14.7" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 81.4" "Lineage enriched" "Detected in single" 98 "T-cells: 81.4" "Cell line enriched" "Detected in some" 10 "HL-60: 10.4" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.69e-4)" "unprognostic (3.82e-4)" "unprognostic (3.66e-2)" "unprognostic (2.55e-2)" "unprognostic (8.55e-2)" "unprognostic (9.93e-5)" "unprognostic (4.36e-1)" "unprognostic (1.94e-2)" "unprognostic (1.09e-2)" "unprognostic (3.42e-2)" "unprognostic (5.90e-2)" "unprognostic (2.27e-1)" "unprognostic (1.78e-3)" "unprognostic (2.40e-1)" "unprognostic (2.22e-2)" "unprognostic (4.18e-2)" "unprognostic (2.01e-2)" 0.2 0.0 0.0 2.7 0.1 0.8 0.5 0.0 0.1 0.1 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.2 0.0 0.9 5.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.7 0.1 1.6 0.0 0.0 0.1 1.2 0.1 0.0 2.9 0.8 0.0 0.0 14.7 0.2 0.0 10.6 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.5 0.3 14.7 0.0 34.6 47.9 0.0 0.1 48.9 21.3 0.8 0.1 0.2 0.2 81.4 12.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 TRBV7-2 "TCRBV6S5A1N1, TCRBV7S2, TRBV72" ENSG00000282939 "T cell receptor beta variable 7-2" A0A1B0GXF2 7 142352819-142353358 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "epididymis: 35.6;lymphoid tissue: 85.5" "Cell type enriched" "Detected in some" 5 "T-cells: 33.0" "Region enriched" "Detected in single" 5 "hypothalamus: 1.1" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 397.4;T-reg: 570.3" "Lineage enriched" "Detected in many" 79 "T-cells: 570.3" "Group enriched" "Detected in some" 9 "JURKAT: 55.7;MOLT-4: 93.6;U-937: 49.0" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" 0.9 0.1 0.0 15.0 0.1 0.0 2.2 0.0 0.2 2.2 0.0 1.2 1.7 0.0 35.6 0.6 0.5 0.0 0.2 0.0 1.1 0.5 0.3 5.5 49.0 0.0 0.0 0.1 0.2 0.0 1.0 0.1 0.0 0.3 4.6 0.0 0.4 0.4 0.0 0.2 4.7 1.1 0.0 5.8 4.7 0.0 0.2 85.5 0.7 0.0 43.0 2.9 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.7 0.0 0.0 0.0 0.0 93.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 1.4 0.3 0.0 0.0 49.0 0.0 1.1 2.3 0.7 11.9 1.2 55.5 0.7 397.4 178.6 2.7 0.7 302.2 110.6 1.2 0.5 1.9 7.2 570.3 104.9 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 0.0 0.0 0.0 0.2 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 TRBV7-6 "TCRBV6S3A1N1T, TCRBV7S6, TRBV76" ENSG00000211727 "T cell receptor beta variable 7-6" A0A1B0GX31 7 142492132-142492673 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 35.3" "Group enriched" "Detected in some" 15 "Gastric mucus-secreting cells: 5.1;T-cells: 7.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 22 "memory CD4 T-cell: 54.7;memory CD8 T-cell: 42.7;naive CD4 T-cell: 62.0;naive CD8 T-cell: 37.2;T-reg: 86.1" "Lineage enriched" "Detected in many" 52 "T-cells: 86.1" "Not detected" "Not detected" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (4.74e-2)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (4.25e-5)" "unprognostic (4.86e-3)" "unprognostic (4.06e-5)" "unprognostic (7.74e-2)" "unprognostic (3.83e-5)" "unprognostic (6.50e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-1)" "unprognostic (1.76e-1)" "unprognostic (9.86e-5)" "unprognostic (1.83e-1)" "unprognostic (7.27e-2)" "unprognostic (5.90e-2)" "unprognostic (6.22e-3)" 0.1 0.0 0.5 3.7 0.3 1.3 0.2 0.2 0.4 0.1 0.1 0.6 0.0 0.1 5.3 1.7 0.1 1.4 0.0 0.5 0.2 0.1 0.4 0.8 6.9 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.6 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.4 3.7 1.1 0.5 1.0 35.3 0.2 0.0 7.6 2.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 2.5 0.1 54.7 42.7 0.1 0.3 62.0 37.2 1.6 0.1 0.1 0.1 86.1 17.1 0.5 0.3 0.2 0.4 0.5 0.2 0.5 0.3 0.3 0.4 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 TRGV2 "TCRGV2, VIS2" ENSG00000233306 "T cell receptor gamma variable 2" A0A075B6R0 7 38362864-38363518 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 6.6" "Cell type enriched" "Detected in some" 5 "T-cells: 19.2" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 147.8" "Lineage enriched" "Detected in many" 22 "T-cells: 147.8" "Cell line enriched" "Detected in some" 4 "Karpas-707: 17.4" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (1.51e-3)" "unprognostic (8.88e-5)" "unprognostic (1.77e-1)" "unprognostic (1.01e-2)" "unprognostic (1.72e-1)" "unprognostic (4.31e-4)" "unprognostic (1.50e-3)" "unprognostic (1.13e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (7.48e-2)" "unprognostic (3.02e-1)" "unprognostic (4.21e-5)" "unprognostic (1.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.25e-1)" "unprognostic (4.87e-3)" 0.4 0.6 0.0 1.6 0.0 0.9 0.1 0.0 0.2 0.2 0.2 0.8 0.8 0.3 0.1 0.1 0.3 1.0 0.2 0.0 0.0 0.1 0.3 0.9 5.0 0.7 0.4 0.0 0.1 0.0 0.1 0.0 0.2 1.2 0.6 0.1 0.9 0.1 0.1 0.2 1.4 0.4 0.1 6.6 0.7 0.3 0.4 4.8 0.3 0.0 0.7 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 2.4 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 1.0 17.4 0.0 0.0 0.5 0.8 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.7 1.7 0.1 0.0 3.8 0.0 0.2 0.4 0.0 59.4 0.2 58.4 0.1 29.7 147.8 1.4 0.2 7.0 54.9 0.9 6.8 0.1 1.5 0.6 22.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5" "Cell type enhanced" "Detected in many" "Ductal cells: 53.1;Hepatocytes: 38.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 630.3;hTCEpi: 401.9;hTERT-HME1: 461.8;SK-MEL-30: 615.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" 8.0 16.4 5.6 4.0 5.4 16.1 7.8 6.0 6.7 4.4 6.5 4.4 1.3 2.9 3.0 20.5 2.2 2.6 4.0 5.1 6.5 9.9 80.5 15.4 6.5 5.5 5.5 3.2 17.3 13.3 15.2 8.4 5.6 7.8 2.2 2.7 10.4 3.0 1.8 13.6 5.3 1.8 4.4 12.1 10.2 1.4 6.7 5.6 38.2 0.5 5.9 4.8 5.3 4.4 80.9 41.6 5.1 11.9 13.7 17.9 33.7 23.9 65.8 23.0 47.5 86.7 40.0 35.3 22.2 22.5 102.3 62.6 22.6 107.7 21.4 12.4 16.2 27.5 8.9 144.2 630.3 71.5 12.7 73.3 401.9 43.5 461.8 16.2 45.1 86.1 97.3 155.2 2.3 77.3 4.2 87.0 11.8 122.8 133.0 15.2 7.1 77.1 27.0 33.3 14.7 23.0 5.6 192.2 615.5 7.2 55.7 185.6 24.6 11.7 20.6 0.3 36.2 52.3 73.9 63.5 10.5 61.4 43.6 5.1 6.4 1.4 13.2 4.9 9.4 21.0 12.3 15.3 6.7 13.8 13.7 9.8 4.4 10.2 2.6 2.8 9.7 7.8 5.6 5.4 6.0 6.7 5.1 6.5 5.5 5.5 5.6 4.4 6.7 4.4 7.9 3.2 1.5 0.3 9.3 6.8 10.9 20.3 3.4 6.8 12.7 8.3 1.6 11.5 8.5 1.8 4.2 14.1 4.0 3.4 0.0 53.1 0.0 0.2 1.6 15.8 1.2 5.7 2.2 22.7 6.4 3.9 0.0 2.6 5.1 0.5 6.8 38.4 6.4 0.0 3.1 8.8 6.1 3.3 4.4 0.0 1.8 3.0 7.2 0.0 4.2 1.0 14.4 1.0 0.6 24.0 1.9 1.5 10.0 12.2 0.0 0.1 2.9 7.0 6.6 6.5 6.9 2.4 3.1 4.0 5.4 7.1 5.7 3.5 2.2 6.7 TRIM11 "BIA1, RNF92" ENSG00000154370 "Tripartite motif containing 11" Q96F44 1 228393673-228406835 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028541, HPA043879" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA028541: AB_10600833, HPA043879: AB_2678711" "unprognostic (1.73e-1)" "unprognostic (9.73e-3)" "unprognostic (5.48e-3)" "unprognostic (7.73e-2)" "unprognostic (3.27e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (7.42e-5)" "unprognostic (1.08e-1)" "unprognostic (9.74e-2)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.40e-2)" "unprognostic (4.89e-2)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" 10.2 12.1 12.7 8.9 16.0 30.7 10.4 23.9 15.2 14.7 10.1 13.6 7.7 11.5 4.5 20.7 12.7 6.1 8.7 14.4 11.6 12.2 10.2 11.8 12.2 11.6 9.9 11.9 11.9 6.7 9.8 5.6 10.8 15.4 7.1 2.0 17.1 7.0 5.0 17.1 14.6 4.6 8.6 24.1 12.9 14.9 13.2 10.1 11.0 3.1 8.7 11.7 15.6 11.0 28.3 26.3 13.8 19.1 10.2 8.4 65.1 18.1 12.1 20.5 16.4 32.2 24.0 21.1 19.7 12.2 13.5 45.1 16.8 17.4 8.6 23.6 40.5 17.5 26.7 17.6 27.6 22.2 25.6 11.3 27.2 21.3 10.6 10.5 10.2 33.9 40.7 26.4 10.7 18.2 27.1 35.1 35.3 23.9 22.9 26.3 12.5 25.8 13.4 34.0 22.9 42.0 15.1 42.2 24.7 5.6 29.9 36.8 11.6 13.0 18.3 30.6 37.9 26.9 19.3 18.9 16.1 17.7 20.9 5.2 4.5 5.6 5.5 5.3 5.9 3.7 6.4 7.1 4.4 3.5 3.6 5.1 6.2 6.2 7.5 3.5 6.4 3.9 12.7 16.0 23.9 15.2 14.4 11.6 11.6 9.9 10.8 8.6 13.2 11.0 7.8 3.2 5.8 1.6 12.1 15.8 16.3 7.4 10.8 12.1 13.3 10.7 3.6 12.8 10.4 1.8 2.1 15.7 21.6 28.1 17.6 14.8 154.2 11.2 10.2 10.1 14.4 12.6 9.8 11.0 15.5 8.5 23.4 17.1 5.7 13.4 8.9 5.7 11.8 5.0 4.7 21.7 4.1 12.6 9.3 16.5 9.6 11.0 5.4 2.8 22.0 10.3 30.9 3.0 3.2 18.3 21.1 7.5 12.8 17.4 17.8 9.9 7.3 1.6 6.6 8.4 9.1 7.3 12.4 15.8 19.5 57.3 18.9 14.9 17.6 30.1 TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 600.1;skin 1: 551.2;vagina: 269.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 272.0;Basal squamous epithelial cells: 250.4;Late spermatids: 150.3;Squamous epithelial cells: 552.9;Suprabasal keratinocytes: 460.6;Urothelial cells: 159.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 399.9;HBEC3-KT: 107.5;hTCEpi: 476.0;RT4: 190.5;SiHa: 268.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 4.0" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" 2.5 1.0 0.1 0.4 0.2 0.4 41.7 0.0 0.4 133.8 1.6 3.0 1.7 2.6 4.8 600.1 17.4 3.5 0.4 0.3 0.0 1.7 1.8 3.7 0.0 1.8 0.6 0.4 1.0 0.0 8.1 30.7 1.8 31.4 2.6 0.3 131.5 23.7 2.2 551.2 1.0 1.5 2.6 0.3 1.4 2.7 0.0 19.9 0.4 0.2 107.2 55.8 269.1 0.6 34.4 2.5 0.0 0.0 0.0 0.0 0.9 0.1 0.8 0.2 0.1 0.8 25.6 0.2 3.9 0.2 0.5 399.9 0.0 107.5 0.0 0.1 0.0 0.2 25.4 0.4 0.0 0.2 0.5 0.0 476.0 0.0 2.6 0.0 0.0 0.0 0.2 0.7 0.0 4.4 0.0 0.0 0.1 11.4 0.1 0.0 0.3 0.0 0.3 190.5 1.3 5.9 268.3 35.2 0.1 0.2 1.9 0.0 0.4 0.1 2.1 0.2 0.1 0.2 0.3 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.0 1.8 0.6 1.8 2.6 0.0 0.6 0.5 0.0 1.5 3.3 0.2 272.0 106.1 76.4 250.4 0.0 9.5 58.8 1.2 1.5 39.2 0.0 0.0 41.0 0.2 11.3 0.0 5.0 28.1 8.7 0.8 3.4 2.4 0.0 0.5 4.3 7.1 5.6 1.1 3.6 1.3 0.0 0.0 0.4 5.0 0.0 0.1 2.1 12.2 0.0 30.3 150.3 0.6 1.4 23.2 1.0 0.0 0.0 0.0 0.0 0.1 57.1 11.3 0.0 0.0 66.0 0.2 0.6 64.6 0.0 0.0 0.1 4.9 0.8 2.6 552.9 460.6 24.8 2.4 0.1 3.7 159.3 TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA043396: AB_2678460, HPA048233: AB_2680321" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "prognostic favorable (2.20e-4)" "unprognostic (4.01e-2)" "unprognostic (3.88e-2)" "unprognostic (1.61e-3)" "unprognostic (2.84e-1)" "unprognostic (2.24e-1)" "unprognostic (3.91e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" 9.5 4.6 6.4 4.6 6.2 1.3 10.3 11.6 7.5 11.2 0.0 13.0 17.8 13.5 1.8 4.8 10.1 4.1 8.0 5.8 3.4 6.3 6.3 9.7 2.4 8.5 3.1 8.7 6.4 2.7 5.9 3.9 9.4 9.5 4.8 4.8 9.0 5.4 11.5 8.4 15.7 5.6 2.2 5.7 10.1 3.8 5.9 1.5 6.8 4.8 1.6 11.2 9.3 6.1 7.2 12.4 4.9 8.3 8.1 7.8 6.7 10.3 6.1 7.8 8.6 7.6 5.0 3.9 3.6 7.9 9.1 5.0 5.1 7.7 3.0 4.8 7.6 1.2 13.5 5.3 5.2 0.4 4.1 6.7 3.7 6.1 3.2 3.3 8.0 2.9 1.7 4.7 7.8 15.2 0.3 1.0 3.5 15.2 10.7 2.4 4.2 4.9 1.9 3.8 5.1 7.8 5.7 54.9 6.6 2.5 20.8 1.3 13.4 20.3 9.5 15.0 6.9 5.5 3.6 0.8 11.0 1.7 7.6 0.0 1.0 0.6 0.5 1.0 0.4 0.1 0.4 0.4 1.2 0.1 0.1 0.6 0.0 0.6 0.2 0.2 0.5 0.5 6.4 6.2 11.6 7.5 5.8 3.4 8.5 3.1 9.4 2.2 5.9 6.1 8.5 6.4 0.0 9.8 2.4 4.8 2.8 2.8 3.4 8.8 8.5 6.0 2.2 2.8 2.7 0.0 10.4 1.8 3.5 16.0 0.0 3.1 3.9 2.8 4.4 6.5 4.8 0.4 13.2 3.5 2.2 6.9 5.6 7.3 1.3 3.6 4.6 2.5 4.7 8.4 12.2 11.4 4.1 0.8 6.5 5.6 5.9 3.5 7.2 11.2 3.4 2.2 3.1 5.0 10.2 3.1 5.4 5.3 2.5 3.2 28.7 3.1 8.4 9.6 13.1 5.0 11.3 3.1 6.0 3.7 5.4 0.8 3.4 3.3 6.6 2.3 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "Vesicles, Focal adhesion sites" "HPA050061: AB_2681001" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 3.1 6.6 8.7 2.9 13.1 4.8 3.6 10.0 11.9 3.2 2.3 3.2 2.4 3.1 2.6 5.1 3.0 2.0 3.5 8.5 10.4 3.5 1.8 3.1 4.6 10.7 11.3 3.7 3.1 2.9 6.4 3.4 12.1 5.1 2.1 2.1 5.2 2.9 4.9 12.5 4.2 2.8 7.4 5.1 4.3 2.3 12.4 5.2 3.9 2.5 4.5 4.8 4.4 21.0 3.7 2.7 23.9 3.9 5.7 2.5 7.6 3.4 9.9 6.3 5.5 3.0 3.7 5.9 3.8 3.0 3.2 7.2 5.0 4.3 5.6 5.8 3.8 6.5 3.2 2.5 5.7 2.2 16.2 5.2 3.9 8.7 2.0 9.9 6.3 5.0 1.1 3.8 6.1 9.9 6.8 2.0 6.0 4.3 3.5 8.6 12.8 2.7 3.8 9.6 6.0 3.7 3.8 14.5 16.8 12.6 4.1 1.4 6.3 2.7 3.8 8.1 2.8 6.9 3.3 2.7 5.1 3.9 3.5 1.2 1.0 3.4 1.3 1.8 2.3 1.1 1.9 1.8 0.9 1.4 1.3 1.2 2.3 1.0 1.1 0.4 4.7 1.1 8.7 13.1 10.0 11.9 8.5 10.4 10.7 11.3 12.1 7.4 12.4 21.0 2.0 3.2 2.2 2.6 1.8 2.7 0.8 1.7 2.8 3.4 3.5 1.9 0.9 0.0 1.2 1.8 0.0 1.1 2.5 1.5 0.0 1.4 0.5 0.6 1.1 1.4 1.8 0.4 1.9 1.9 1.8 2.1 4.1 1.3 1.3 1.7 1.1 0.7 1.2 10.1 10.2 1.5 4.1 1.2 1.6 0.5 2.5 1.3 0.0 10.3 1.4 1.5 3.1 50.8 26.0 2.6 0.6 4.9 2.6 2.1 1.2 1.0 0.4 1.0 6.6 2.0 2.1 1.3 0.6 2.8 4.7 1.4 3.0 3.4 0.9 2.0 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 205.7;Excitatory neurons: 400.9;Inhibitory neurons: 443.4;Microglial cells: 308.2;Oligodendrocyte precursor cells: 476.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 215.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 35.3 20.5 31.7 11.6 33.3 5.5 31.8 32.2 38.6 23.4 34.5 36.6 6.8 38.9 15.5 14.5 21.2 18.8 31.9 37.2 33.6 24.9 22.1 25.7 10.2 28.1 28.1 52.8 20.6 9.1 28.9 11.6 26.6 28.2 13.6 10.2 17.4 11.1 20.9 18.7 27.8 19.2 26.4 38.9 22.9 17.2 31.4 13.3 17.0 17.4 10.6 27.1 20.5 27.2 43.7 15.9 37.2 18.0 78.6 101.0 41.3 40.4 49.2 32.6 36.9 10.3 17.4 10.4 28.0 56.6 79.6 13.0 6.5 19.4 66.6 25.8 8.0 5.5 46.1 13.2 40.0 13.9 14.8 47.6 19.9 114.4 36.4 30.3 28.8 6.8 1.4 6.8 78.7 8.3 0.1 9.5 9.3 4.8 13.7 9.9 22.9 34.2 31.6 20.5 17.1 67.5 34.3 9.0 18.9 47.1 5.3 2.0 66.4 61.4 38.3 44.7 48.4 0.3 2.2 12.9 215.1 8.8 14.8 0.1 0.5 0.0 0.0 0.7 0.1 0.7 0.0 0.0 0.5 1.8 0.0 0.0 0.0 1.6 0.6 1.1 0.3 0.1 31.7 33.3 32.2 38.6 37.2 33.6 28.1 28.1 26.6 26.4 31.4 27.2 33.0 19.2 25.9 205.7 16.6 16.4 13.0 15.6 17.1 30.5 21.9 15.0 19.3 10.0 21.0 11.0 14.6 9.7 5.6 24.8 0.0 21.2 2.9 11.7 24.8 28.7 18.0 6.5 400.9 14.2 22.0 38.9 7.7 34.2 17.7 17.2 14.6 17.1 14.2 28.6 443.4 20.6 14.2 15.4 22.1 6.6 78.6 20.2 5.4 308.2 12.1 7.3 2.1 476.5 80.4 38.5 14.9 42.9 29.2 52.8 9.2 5.4 18.3 2.7 6.6 27.5 20.0 3.5 6.2 7.2 13.8 8.2 3.8 11.7 19.4 20.3 TRPC3 ENSG00000138741 "Transient receptor potential cation channel subfamily C member 3" Q13507 4 121874481-121952060 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;pituitary gland: 7.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;Inhibitory neurons: 82.7;Oligodendrocyte precursor cells: 33.7;Rod photoreceptor cells: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 2.3;Karpas-707: 2.6;U-2 OS: 1.5;U-251 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 57.8" "Low region specificity" "Detected in many" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (3.12e-2)" "unprognostic (5.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.12e-3)" "unprognostic (9.80e-2)" "unprognostic (4.80e-3)" "unprognostic (2.38e-1)" "unprognostic (3.26e-1)" "unprognostic (1.06e-1)" "unprognostic (4.33e-3)" "unprognostic (2.67e-3)" "unprognostic (1.39e-1)" "unprognostic (2.23e-1)" "unprognostic (8.42e-3)" 0.3 0.0 2.3 0.1 4.0 0.0 0.2 4.6 5.8 0.8 0.1 0.2 0.1 0.4 0.2 0.0 0.5 0.8 0.2 0.8 3.2 0.1 0.1 0.9 0.1 10.4 2.8 0.1 0.0 0.2 7.4 1.1 2.2 0.2 0.1 3.9 0.1 0.6 0.4 0.1 0.5 2.6 1.6 0.2 0.2 0.4 4.6 0.0 0.1 0.2 0.0 1.7 0.7 1.7 0.0 0.0 0.8 0.1 0.1 0.1 0.0 0.4 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.5 0.3 0.1 0.4 0.0 0.1 0.0 1.3 2.3 0.2 0.0 0.1 0.7 0.3 0.2 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.6 0.5 0.1 0.8 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.1 1.2 1.5 0.1 1.5 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.3 4.0 4.6 5.8 0.8 3.2 10.4 2.8 2.2 1.6 4.6 1.7 0.5 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.8 0.0 0.0 0.0 8.4 0.0 0.5 0.0 0.0 0.0 2.3 0.0 0.3 0.2 0.0 0.0 18.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 82.7 0.0 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.1 4.6 0.0 33.7 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 32.0 0.0 0.3 1.4 0.5 0.8 0.0 0.0 0.0 0.5 0.5 0.0 0.1 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TSPAN18 TSPAN ENSG00000157570 "Tetraspanin 18" Q96SJ8 11 44726465-44932423 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 83.5" "Group enriched" "Detected in many" 6 "Adipocytes: 72.2;Cardiomyocytes: 22.3;Early spermatids: 29.7;Endothelial cells: 51.8;Hepatic stellate cells: 70.3;Proximal tubular cells: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 36.7;CAPAN-2: 61.5;GAMG: 35.2;HDLM-2: 48.7;NTERA-2: 33.0;RH-30: 38.4;SCLC-21H: 31.9;SH-SY5Y: 36.2;SuSa: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (8.53e-3)" "unprognostic (3.48e-2)" "unprognostic (6.30e-2)" "unprognostic (8.64e-2)" "unprognostic (7.17e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.04e-3)" "unprognostic (6.78e-3)" "unprognostic (3.22e-1)" "unprognostic (2.19e-1)" "unprognostic (5.59e-2)" 22.2 46.1 5.8 10.4 4.3 1.2 10.0 30.5 8.2 14.4 3.6 47.9 6.7 46.7 3.6 21.0 20.8 13.3 83.5 26.1 4.6 14.5 4.9 22.4 7.7 5.1 10.4 7.4 1.6 3.9 5.4 30.2 4.9 15.8 9.9 1.0 3.3 41.4 14.7 6.3 16.4 46.6 8.9 14.1 16.6 4.0 10.8 4.0 14.8 19.9 4.2 23.1 10.2 2.3 0.0 0.6 36.7 0.5 0.0 0.0 0.0 0.6 0.5 2.3 0.1 7.3 61.5 0.0 16.4 1.0 35.2 0.0 6.6 0.2 0.6 48.7 2.4 0.2 5.0 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.0 0.0 14.3 0.2 1.1 0.0 0.1 0.0 0.0 0.1 33.0 0.1 1.0 0.1 38.4 0.2 0.0 0.0 31.9 36.2 0.4 0.1 0.1 99.8 0.2 0.1 1.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 1.6 1.0 0.0 0.0 1.6 0.1 0.0 0.8 0.2 1.1 0.5 0.0 0.0 1.3 0.2 0.3 0.5 0.0 0.0 0.3 1.7 5.8 4.3 30.5 8.2 26.1 4.6 5.1 10.4 4.9 8.9 10.8 2.3 72.2 0.0 3.7 5.5 1.5 1.7 0.1 0.0 0.6 1.8 1.0 0.3 22.3 0.0 0.0 7.3 0.0 0.1 1.1 0.0 0.0 0.4 29.7 0.7 0.9 51.8 0.0 3.6 2.7 0.2 0.2 6.8 0.5 1.4 1.3 0.0 70.3 1.0 0.4 1.7 4.1 0.0 0.0 2.5 2.6 5.6 2.8 3.4 7.2 2.8 0.2 0.1 0.0 4.0 1.3 0.7 0.0 1.5 0.6 0.2 0.0 20.2 0.0 0.5 0.0 4.9 2.0 0.6 1.0 0.0 1.1 0.3 3.0 3.2 0.0 0.1 TTC16 FLJ32780 ENSG00000167094 "Tetratricopeptide repeat domain 16" Q8NEE8 9 127716079-127731590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "fallopian tube: 6.9;testis: 16.0" "Group enriched" "Detected in some" 4 "Early spermatids: 103.1;Late spermatids: 258.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;naive CD8 T-cell: 1.5" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (3.10e-3)" "unprognostic (1.63e-3)" "unprognostic (3.86e-3)" "unprognostic (2.02e-4)" "unprognostic (4.08e-3)" "unprognostic (2.25e-3)" "unprognostic (8.87e-4)" "unprognostic (2.91e-2)" "unprognostic (2.25e-2)" "unprognostic (2.36e-1)" "unprognostic (1.96e-3)" "unprognostic (7.32e-2)" "unprognostic (9.14e-3)" "unprognostic (6.35e-3)" "unprognostic (5.29e-2)" "unprognostic (1.17e-1)" "unprognostic (5.54e-3)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.2 0.0 6.9 0.1 0.0 0.1 0.1 0.1 0.0 0.7 0.4 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.0 0.0 0.5 1.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.6 0.2 0.2 0.1 0.1 0.1 0.0 0.6 0.0 0.4 0.1 0.1 1.0 0.0 0.0 0.2 0.1 0.8 1.5 5.7 0.0 0.0 0.0 13.7 0.0 0.0 0.0 103.1 6.0 0.1 0.5 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.0 0.3 0.0 258.3 1.2 0.3 1.8 0.0 0.3 0.2 9.2 4.5 0.1 0.0 0.0 3.8 2.6 0.0 0.0 0.4 41.8 0.5 0.0 0.1 0.4 17.9 1.6 0.0 0.0 0.0 7.4 3.8 0.0 0.1 TTC24 ENSG00000187862 "Tetratricopeptide repeat domain 24" A2A3L6 1 156579723-156587719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "lymphoid tissue: 21.2" "Group enriched" "Detected in some" 5 "B-cells: 4.6;dendritic cells: 3.6;Erythroid cells: 1.3;NK-cells: 2.1;Skeletal myocytes: 1.7;T-cells: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NK-cell: 3.7;plasmacytoid DC: 12.4" "Group enriched" "Detected in many" 4 "dendritic cells: 12.4;NK-cells: 3.7" "Cell line enhanced" "Detected in some" "JURKAT: 10.3;MOLT-4: 3.8;REH: 11.9;U-698: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA029799 Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA029799: AB_10601684" "unprognostic (2.43e-3)" "unprognostic (5.61e-5)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "unprognostic (4.48e-6)" "unprognostic (6.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.42e-1)" "unprognostic (7.96e-2)" "unprognostic (4.87e-9)" "unprognostic (1.07e-2)" "unprognostic (5.19e-2)" "unprognostic (2.22e-2)" "unprognostic (9.76e-4)" 0.1 0.0 0.0 1.9 0.1 1.8 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 5.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.2 0.2 0.0 0.0 3.0 0.4 0.1 0.0 21.2 0.1 0.0 5.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.1 0.0 3.8 0.7 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 1.1 0.1 1.7 0.2 1.8 0.2 3.7 0.0 12.4 0.0 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 59.5" "Group enriched" "Detected in many" 9 "Early spermatids: 425.0;Late spermatids: 616.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 31.7" "Lineage enriched" "Detected in single" 42 "dendritic cells: 31.7" "Cell line enhanced" "Detected in many" "HDLM-2: 70.6;MCF7: 52.4;SK-BR-3: 153.7;T-47d: 111.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" 2.2 8.2 3.5 3.3 3.5 1.7 35.9 3.0 9.6 14.1 0.0 29.5 6.1 1.0 15.9 18.4 7.5 14.9 15.3 1.0 11.4 26.6 2.8 9.1 1.4 7.4 5.3 0.3 13.5 13.5 11.0 0.3 14.0 20.5 35.2 4.6 11.5 4.2 4.1 10.5 8.1 1.6 2.2 0.3 29.4 59.5 7.7 0.5 10.1 1.7 2.0 8.0 9.4 3.7 6.4 3.4 0.7 0.3 0.4 0.7 28.2 0.3 0.2 0.2 0.2 18.2 2.8 0.1 9.6 0.4 0.4 0.2 3.8 0.2 0.1 70.6 9.7 0.5 1.8 3.2 1.1 0.0 0.7 0.1 1.6 0.1 0.0 0.8 1.4 0.2 0.4 0.1 0.2 52.4 0.6 0.2 4.8 33.8 0.6 0.1 0.2 4.3 28.6 9.1 22.1 1.6 0.5 153.7 1.8 2.0 111.7 0.8 0.8 0.4 2.5 0.5 0.5 5.4 7.1 0.2 2.1 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.0 0.0 31.7 0.0 0.3 3.5 3.5 3.0 9.6 1.0 11.4 7.4 5.3 14.0 2.2 7.7 3.7 0.4 3.2 25.2 1.3 1.1 1.5 5.3 1.7 0.0 2.5 30.8 15.1 13.0 5.7 6.4 9.2 0.0 0.5 15.3 29.3 11.7 38.9 425.0 5.4 3.0 1.9 41.4 9.7 9.7 52.7 4.8 0.9 21.9 9.5 3.8 0.5 0.4 0.6 2.0 0.0 10.2 56.0 6.1 0.3 1.3 616.8 2.5 0.9 0.0 1.0 2.6 1.7 0.0 0.0 0.9 30.5 13.7 2.6 0.4 12.0 2.7 24.4 9.3 7.3 6.6 1.8 1.3 22.8 6.5 4.8 6.5 3.4 1.7 0.5 20.7 14.6 TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595847-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 7.9;prostate: 17.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 13.8;Club cells: 11.1;Early spermatids: 39.1;Late spermatids: 18.1;Spermatocytes: 10.7" "Group enriched" "Detected in some" 7 "breast cancer: 2.2;prostate cancer: 3.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 8.4;MCF7: 12.2;RT4: 8.4;T-47d: 22.8" "Not detected" "Not detected" "Region enriched" "Detected in some" 7 "midbrain: 9.7" HPA069293 Approved Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Centrosome "HPA069293: AB_2686110" "unprognostic (7.92e-2)" "unprognostic (6.95e-2)" "unprognostic (9.22e-2)" "unprognostic (1.98e-1)" "unprognostic (7.06e-2)" "unprognostic (1.22e-2)" "unprognostic (1.68e-1)" "unprognostic (3.60e-4)" "unprognostic (6.75e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-4)" "unprognostic (5.60e-2)" "unprognostic (8.91e-8)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (6.07e-3)" 0.0 0.0 0.5 0.2 0.8 0.0 7.9 0.1 0.8 0.1 1.1 1.0 0.6 0.0 0.0 0.4 0.3 0.7 0.0 0.7 1.0 0.0 3.5 1.1 0.0 2.5 5.0 0.0 0.0 0.0 0.3 0.0 1.3 17.5 0.5 0.0 2.7 0.1 0.0 0.7 0.7 0.0 3.9 0.0 3.6 5.8 3.9 0.0 0.0 0.0 0.1 1.4 0.3 1.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.6 0.0 0.4 0.0 0.0 2.4 1.3 0.2 0.0 0.0 3.4 0.0 1.2 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 12.2 0.0 0.0 0.0 1.7 4.5 0.0 0.0 0.0 1.0 8.4 2.4 0.0 0.0 4.5 0.0 0.0 22.8 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.1 0.8 0.7 1.0 2.5 5.0 1.3 3.9 3.9 1.0 0.2 0.0 8.4 0.3 0.1 0.0 2.8 1.5 6.2 0.0 13.8 6.9 0.8 1.5 11.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 39.1 0.0 0.0 0.4 7.7 0.0 6.4 0.0 0.0 0.4 7.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 1.0 0.7 0.0 0.0 0.0 18.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.8 0.4 0.0 4.9 0.0 0.0 7.5 0.0 0.0 0.2 0.4 10.7 1.9 2.3 0.0 0.0 0.3 0.0 1.1 3.1 TTLL9 "C20orf125, dJ310O13.1" ENSG00000131044 "Tubulin tyrosine ligase like 9" Q3SXZ7 20 31870702-31944963 "Cancer-related genes, Predicted intracellular proteins" Ligase "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.4;choroid plexus: 10.3;epididymis: 2.6;fallopian tube: 6.2;testis: 5.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 20.8;Early spermatids: 39.3;Endometrial ciliated cells: 25.8;Late spermatids: 69.8;Oligodendrocytes: 28.0;Respiratory ciliated cells: 50.2" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041772, HPA055676" Uncertain Uncertain Nucleoplasm,Microtubules NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Microtubules" "HPA041772: AB_10959904, HPA055676: AB_2682881" "unprognostic (8.77e-2)" "unprognostic (8.19e-3)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (4.63e-1)" "unprognostic (1.53e-3)" "unprognostic (1.80e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.59e-1)" "unprognostic (9.05e-3)" "unprognostic (6.17e-2)" "unprognostic (8.35e-3)" "unprognostic (1.84e-1)" "unprognostic (1.70e-1)" "unprognostic (1.25e-3)" "unprognostic (2.23e-2)" 0.1 0.1 2.0 0.0 2.1 0.0 0.2 2.2 2.2 0.9 10.3 0.0 0.0 0.1 2.6 0.0 6.2 0.1 0.0 2.5 2.3 0.7 0.0 1.1 0.1 3.8 4.4 0.1 0.2 0.6 0.9 0.0 3.0 0.2 0.0 0.4 0.0 0.4 0.0 0.0 0.1 0.0 3.0 0.2 0.0 5.0 2.4 0.0 0.6 0.0 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.1 2.2 2.2 2.5 2.3 3.8 4.4 3.0 3.0 2.4 2.6 0.2 12.8 20.8 13.1 0.1 0.1 1.1 1.1 0.0 1.8 0.4 0.6 0.9 0.0 8.1 0.0 4.2 0.1 0.1 0.0 0.0 0.2 39.3 25.8 0.7 1.1 0.0 0.0 5.6 0.0 0.0 1.6 0.0 0.8 7.6 0.8 0.4 0.1 0.0 5.0 7.8 0.2 2.0 0.6 0.5 69.8 1.5 3.5 0.0 1.0 0.8 0.4 0.0 15.1 28.0 0.1 0.0 1.2 0.0 0.5 0.0 0.2 50.2 0.8 0.0 0.8 0.7 13.8 1.2 0.0 0.1 0.0 2.7 0.4 0.0 0.4 TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 42 "Plasma cells: 677.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.7" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.7" "Cell line enhanced" "Detected in all" "RPMI-8226: 2833.2;U-266/84: 6053.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 6900000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA034677: AB_2674275, HPA034678: AB_2674276" "unprognostic (3.15e-1)" "unprognostic (1.09e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (6.07e-2)" "unprognostic (5.81e-2)" "unprognostic (3.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.05e-1)" "unprognostic (7.98e-2)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" 97.4 74.8 21.1 173.0 23.4 61.8 163.4 22.0 22.5 132.2 52.7 266.2 263.5 80.5 85.8 78.2 63.9 98.6 63.3 19.8 23.2 63.1 133.3 90.9 194.2 25.0 24.7 96.4 154.6 68.6 42.5 134.0 23.2 73.2 213.6 4.4 219.3 93.6 25.1 32.9 193.9 121.9 24.9 250.6 287.6 28.3 26.4 54.1 69.6 29.2 263.8 190.9 57.0 25.9 166.1 159.0 111.5 365.9 911.2 388.1 175.9 361.5 349.7 246.2 265.2 238.8 119.0 176.1 620.7 557.2 273.6 127.3 195.5 178.6 280.3 148.8 166.6 267.6 128.3 435.9 268.5 307.2 255.0 266.7 256.8 236.6 259.2 542.1 1334.0 109.7 170.5 1216.5 171.7 147.7 75.2 185.7 142.8 260.5 340.6 128.0 160.4 2833.2 201.1 149.6 168.7 90.5 462.4 280.2 209.4 514.9 143.5 133.9 369.7 280.5 194.2 243.0 386.5 1408.7 6053.9 305.0 144.7 191.7 392.2 0.0 0.4 0.0 0.9 0.7 0.7 13.0 0.2 0.7 1.0 6.9 0.2 0.4 0.0 0.0 0.1 26.7 0.9 0.5 21.1 23.4 22.0 22.5 19.8 23.2 25.0 24.7 23.2 24.9 26.4 25.9 1.3 0.0 4.8 0.0 14.6 0.9 0.2 0.4 3.4 0.0 1.8 1.3 0.2 0.0 2.0 0.0 0.0 0.9 5.6 1.2 0.0 9.0 0.1 1.1 6.9 3.2 4.9 11.2 0.0 10.7 1.9 4.1 6.1 2.3 1.3 0.6 3.9 4.9 1.5 0.0 0.0 15.9 0.0 0.8 0.7 0.0 0.0 1.3 3.6 0.0 1.8 0.1 0.0 0.0 0.0 9.5 1.5 0.4 677.7 0.4 3.2 0.5 1.7 0.5 6.6 0.5 4.2 0.1 0.1 3.9 0.1 1.2 2.0 0.2 5.8 0.2 UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.9;Erythroid cells: 3.8;T-cells: 20.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 7 "HEL: 23.0;JURKAT: 39.0;MOLT-4: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" 0.4 0.6 0.0 5.2 0.0 2.5 0.2 0.0 0.1 0.5 0.1 0.8 1.6 0.5 0.0 0.4 0.4 2.0 0.4 0.0 0.1 0.4 0.7 1.7 11.1 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.4 0.9 0.0 0.9 0.1 0.2 0.3 2.4 0.1 0.1 4.4 1.9 0.1 0.0 18.9 0.5 0.1 5.1 1.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 23.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.4 0.0 0.0 0.0 47.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.9 0.0 22.9 0.1 28.2 24.8 0.0 0.0 32.2 24.0 0.5 2.5 0.1 0.1 27.9 10.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.8 0.0 0.0 0.2 0.3 1.0 0.0 0.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 3.8 0.0 0.0 0.0 0.4 1.1 0.5 1.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.6 0.0 0.3 0.0 20.5 0.0 0.0 0.0 UBD FAT10 ENSG00000213886 "Ubiquitin D" O15205 6 29555515-29559732 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 151.3" "Group enriched" "Detected in many" 7 "Ductal cells: 534.8;Exocrine glandular cells: 273.8;monocytes: 151.9;Pancreatic endocrine cells: 510.6" "Cancer enhanced" "Detected in all" "liver cancer: 75.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 63.9;RT4: 52.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043710 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nucleoli fibrillar center" "HPA043710: AB_2756303" "unprognostic (2.99e-3)" "unprognostic (4.16e-2)" "unprognostic (6.37e-2)" "unprognostic (2.61e-2)" "unprognostic (3.93e-2)" "unprognostic (3.53e-3)" "unprognostic (1.60e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-2)" "prognostic favorable (7.35e-4)" "unprognostic (1.28e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (4.04e-2)" "unprognostic (6.02e-2)" "unprognostic (8.40e-2)" "unprognostic (1.21e-2)" 4.2 0.4 0.3 35.6 0.4 0.0 8.6 0.3 0.7 1.7 0.3 13.3 4.2 1.9 1.2 8.3 4.7 0.9 0.6 0.3 0.3 23.2 25.4 10.9 87.5 0.4 0.3 1.2 27.3 1.7 1.4 0.0 0.3 11.9 19.0 0.0 14.6 1.3 0.4 1.8 31.1 1.2 0.3 22.9 27.1 0.8 0.3 90.2 3.0 0.1 151.3 25.8 1.7 0.3 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 63.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 52.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.9 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.3 0.7 0.3 0.3 0.4 0.3 0.3 0.3 0.3 0.3 0.2 3.2 3.1 0.0 0.7 0.1 0.1 2.3 16.5 0.0 1.9 1.9 0.0 21.5 13.3 0.0 0.0 0.0 0.1 6.9 1.9 534.8 0.0 0.3 0.2 7.1 3.6 0.0 0.0 273.8 0.0 2.2 13.3 0.2 0.0 0.0 0.7 0.3 0.1 0.0 0.0 5.2 6.1 0.3 0.0 0.0 0.0 1.2 0.0 0.0 151.9 0.0 0.0 0.0 0.0 510.6 8.3 0.0 0.0 0.5 49.1 1.1 9.7 0.0 0.0 0.0 3.4 0.0 0.0 2.2 0.0 0.0 0.2 0.0 11.1 0.1 UFSP1 UFSP ENSG00000176125 "UFM1 specific peptidase 1 (inactive)" Q6NVU6 7 100888721-100889715 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 7.9;Proximal tubular cells: 7.4;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027099 Uncertain NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA027099: AB_2214069" "unprognostic (8.56e-2)" "unprognostic (2.62e-2)" "unprognostic (2.23e-1)" "unprognostic (1.94e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-2)" "unprognostic (2.14e-1)" "unprognostic (2.11e-1)" "unprognostic (3.55e-3)" "unprognostic (5.71e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-1)" "unprognostic (2.48e-1)" "unprognostic (2.46e-1)" "unprognostic (3.09e-2)" 2.0 2.7 1.2 0.9 1.3 0.6 1.6 1.9 1.7 1.5 0.2 1.8 1.0 2.4 1.3 1.9 1.8 0.1 1.6 0.9 1.2 2.1 3.1 1.0 0.6 1.4 1.5 0.9 3.1 1.0 2.3 0.4 1.4 1.8 0.5 0.3 1.7 1.0 3.7 1.1 1.5 0.8 1.2 1.6 1.9 0.7 1.1 0.8 1.4 1.2 0.4 2.1 1.1 1.5 2.9 3.7 0.8 3.8 3.6 2.1 2.3 2.2 0.7 0.9 0.6 1.5 2.0 0.7 1.7 1.8 1.4 5.6 1.1 1.3 0.5 2.6 8.2 2.4 3.2 1.8 3.6 1.0 1.1 2.4 1.6 1.2 4.6 1.0 0.3 1.4 3.7 1.7 1.4 7.3 2.4 6.0 2.8 3.0 5.1 1.2 1.1 5.8 1.6 1.3 2.6 4.3 4.4 5.6 2.7 1.1 1.4 0.9 0.9 2.4 2.5 2.6 1.7 1.7 2.2 0.2 0.8 2.0 2.8 0.0 2.4 1.5 3.1 2.1 3.5 1.0 2.6 1.7 2.9 3.9 2.9 3.6 0.4 3.0 2.2 4.4 1.2 1.7 1.2 1.3 1.9 1.7 0.9 1.2 1.4 1.5 1.4 1.2 1.1 1.5 0.7 0.0 0.0 0.0 0.8 0.6 2.3 1.3 1.8 0.4 1.4 1.3 0.8 1.5 0.7 1.8 0.0 2.4 0.8 2.5 7.9 2.2 0.3 2.2 3.6 0.8 3.0 0.8 0.3 2.1 1.2 1.2 1.1 1.2 0.0 0.6 1.8 4.7 1.9 0.0 0.3 2.2 0.0 0.8 0.7 0.4 1.8 0.6 0.0 1.0 0.5 2.5 0.0 1.0 0.2 1.8 5.0 1.9 1.3 3.2 1.6 7.4 0.7 1.0 6.6 1.5 1.5 0.2 0.3 2.4 1.0 1.6 0.8 4.4 2.5 2.2 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 ULK3 "DKFZP434C131, FLJ90566" ENSG00000140474 "Unc-51 like kinase 3" Q6PHR2 15 74836118-74843346 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Autophagy "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 89.7;Horizontal cells: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040474 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA040474: AB_2677003" "unprognostic (3.67e-2)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (2.07e-3)" "unprognostic (1.19e-1)" "unprognostic (1.58e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-2)" "prognostic favorable (7.47e-4)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (1.30e-2)" "unprognostic (1.63e-1)" "unprognostic (1.16e-1)" "unprognostic (4.97e-3)" 7.1 15.2 29.5 6.4 31.5 2.2 6.1 28.1 32.2 13.6 23.0 12.1 5.0 4.4 3.5 35.7 5.5 4.5 15.9 29.4 27.3 17.6 13.8 8.3 5.8 34.0 26.6 5.7 12.0 16.2 12.5 3.5 35.8 9.9 9.4 15.4 11.5 3.1 21.0 24.7 15.7 4.4 26.1 13.1 10.6 7.1 27.8 6.3 7.6 19.0 7.8 9.4 15.4 30.4 6.7 17.7 7.4 14.4 9.3 6.7 6.0 5.1 7.3 10.1 11.1 7.0 15.4 13.0 8.8 6.2 10.8 4.7 23.1 7.6 4.4 26.1 26.1 30.3 25.0 7.4 14.8 10.3 22.5 9.4 14.0 8.2 7.1 3.5 15.8 16.8 10.3 11.9 7.0 9.4 7.3 6.6 10.0 10.6 8.7 18.6 10.3 23.0 6.0 7.4 16.7 22.3 8.6 9.8 25.6 9.1 11.0 26.8 9.4 16.0 8.9 12.7 10.3 20.7 19.7 9.3 7.4 29.5 12.4 5.2 3.5 1.4 10.9 7.3 8.7 3.3 6.4 9.0 3.7 2.8 7.1 4.8 0.8 5.8 6.1 4.0 9.2 5.1 29.5 31.5 28.1 32.2 29.4 27.3 34.0 26.6 35.8 26.1 27.8 30.4 16.5 9.6 15.3 37.2 11.4 10.1 7.5 6.0 10.2 89.7 18.1 13.6 17.1 14.3 6.7 12.9 16.7 9.2 23.3 46.4 19.6 11.0 1.0 8.9 8.8 10.7 11.4 14.1 64.7 11.7 2.5 9.2 23.4 11.9 21.0 6.2 13.2 13.3 16.1 89.2 56.5 17.5 4.1 7.9 8.2 2.2 13.1 11.2 5.4 18.7 13.2 18.4 29.9 16.6 15.3 12.3 17.9 11.7 8.6 10.4 68.5 16.5 8.0 54.5 0.0 12.9 8.8 9.5 17.3 19.7 21.7 5.7 19.7 12.3 27.9 8.9 UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 693 "kidney: 2277.8" "Group enriched" "Detected in some" 146 "Collecting duct cells: 248.3;Distal tubular cells: 950.9" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" NA NA 55000000 66000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2277.8 0.8 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 248.3 0.0 0.0 0.0 0.0 950.9 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 250.1;Extravillous trophoblasts: 260.3;Macrophages: 199.5;Paneth cells: 260.8" "Cancer enhanced" "Detected in all" "testis cancer: 62.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 4 "hTERT-HME1: 362.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA054040: AB_2682352, HPA055394: AB_2682805" "unprognostic (1.16e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (5.96e-2)" "unprognostic (1.01e-1)" "unprognostic (3.21e-3)" "unprognostic (6.36e-2)" "unprognostic (1.78e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.81e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (1.52e-3)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" 16.4 9.4 3.8 7.5 4.4 12.5 10.0 3.0 5.8 16.8 2.0 9.8 4.3 3.9 0.8 66.9 5.7 5.9 8.9 3.1 3.9 39.8 11.9 18.8 3.7 4.2 2.8 1.9 4.6 5.0 7.4 3.8 3.7 4.9 5.3 0.5 14.2 1.1 3.7 3.1 6.5 3.4 1.3 20.3 4.1 2.2 4.4 1.2 8.0 0.9 6.6 9.1 31.2 3.7 19.5 26.0 2.4 5.2 8.9 4.0 29.7 7.9 15.5 14.5 17.5 10.8 9.9 0.0 2.5 9.7 89.9 13.9 5.2 46.1 9.4 4.1 4.5 0.8 4.8 4.6 7.4 0.9 1.3 5.0 21.8 6.4 362.8 5.9 9.1 0.4 1.5 13.5 7.6 2.3 0.0 2.9 9.4 4.2 20.7 0.0 4.8 6.0 33.7 11.5 2.3 1.6 10.2 3.0 63.4 29.3 2.4 0.9 12.4 29.6 22.9 7.3 22.6 21.4 34.7 3.7 29.6 3.0 77.8 11.5 16.0 12.2 11.8 12.1 8.9 0.2 7.8 8.7 6.5 0.6 8.1 8.1 6.2 5.4 14.8 0.5 8.4 10.9 3.8 4.4 3.0 5.8 3.1 3.9 4.2 2.8 3.7 1.3 4.4 3.7 107.4 19.2 58.5 5.2 19.1 46.8 26.3 104.4 19.4 27.6 9.0 16.1 11.6 24.3 51.0 11.0 33.3 15.1 122.9 250.1 70.5 50.5 1.0 42.1 22.4 108.1 13.1 4.4 16.5 40.5 260.3 34.1 5.1 91.1 25.9 3.8 72.5 17.5 110.0 16.8 29.4 35.0 85.5 130.5 118.1 2.4 5.3 199.5 87.2 1.0 61.4 13.3 71.1 4.0 3.6 117.9 260.8 2.2 30.3 30.4 42.8 23.3 11.9 29.2 6.6 21.1 32.2 0.3 9.5 42.9 29.8 78.7 71.0 1.5 29.1 34.9 UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 297.7;skeletal muscle: 311.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 1792.1;Hepatocytes: 2200.3;Proximal enterocytes: 2007.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" 71.0 80.2 74.9 20.6 79.6 39.7 60.5 79.4 103.7 46.8 78.6 91.7 59.7 46.4 18.4 71.6 43.6 25.0 297.7 76.4 76.7 103.4 136.4 48.7 27.4 76.5 77.7 35.5 49.5 46.8 62.7 24.1 76.6 62.0 22.8 13.8 53.9 30.9 311.8 50.4 62.6 22.6 75.6 60.9 77.2 24.7 78.3 24.1 52.6 109.7 19.3 60.9 51.4 79.0 68.9 75.7 34.7 74.5 60.8 40.7 79.9 54.3 45.4 55.5 48.8 121.5 47.3 47.4 51.8 41.8 12.3 46.8 55.5 61.0 26.5 65.0 163.1 40.6 87.3 114.0 60.6 66.1 57.9 62.8 62.6 35.2 41.6 28.6 50.8 66.9 94.8 73.1 36.2 111.5 67.7 72.4 94.8 59.2 176.0 40.4 36.2 148.9 74.6 158.4 69.6 65.9 39.3 86.4 99.7 27.9 59.3 65.1 66.7 44.3 30.0 129.9 57.7 110.4 101.2 54.4 82.6 69.9 64.8 619.6 421.3 521.9 282.7 367.9 287.1 390.0 341.7 316.6 360.5 333.8 324.3 314.1 496.7 273.7 354.9 448.4 407.7 872.4 74.9 79.6 79.4 103.7 76.4 76.7 76.5 77.7 76.6 75.6 78.3 79.0 300.4 269.2 379.1 20.5 287.6 0.0 189.6 0.0 206.6 135.2 715.6 798.8 1731.6 529.0 159.7 634.5 39.6 481.8 380.1 834.6 1792.1 665.4 178.2 290.5 220.2 282.4 452.6 451.6 17.8 811.6 632.1 262.0 342.0 243.5 199.3 152.6 463.3 2200.3 962.9 89.2 17.6 681.7 0.0 783.5 0.0 474.8 252.8 472.2 0.0 10.3 866.6 418.8 568.5 9.5 25.1 855.3 727.0 259.5 384.1 365.5 2007.4 1742.3 267.5 164.4 223.5 192.6 291.3 159.2 145.3 520.3 0.0 512.8 304.3 188.0 717.0 290.3 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 339.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 32.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)" 6.0 12.2 6.3 3.0 7.4 0.2 6.2 10.0 7.9 7.6 7.5 9.2 1.7 6.8 5.6 4.6 9.2 6.0 4.3 5.8 16.0 3.6 1.3 5.2 3.9 28.2 17.2 11.6 13.1 4.6 1.9 4.6 14.1 6.3 2.7 6.8 3.2 4.8 1.7 6.7 5.7 8.8 13.5 6.5 5.0 6.7 22.7 6.5 27.5 5.8 3.7 8.8 7.7 15.6 0.1 3.2 18.2 14.0 21.5 17.8 0.1 7.9 20.5 3.8 9.8 0.0 1.2 6.7 1.7 12.3 9.5 5.7 13.0 6.6 7.6 9.1 9.9 0.2 10.0 0.1 7.9 0.3 2.8 9.2 14.6 9.8 18.1 7.6 0.2 11.1 0.0 0.0 3.0 8.3 0.1 0.0 10.7 32.4 4.2 3.3 2.5 7.7 0.1 14.8 9.4 0.0 26.4 6.3 5.0 13.0 4.7 0.3 0.4 10.9 1.3 2.5 7.4 0.0 0.0 0.0 12.1 5.4 6.3 0.0 0.0 0.0 0.6 0.2 0.4 0.3 0.4 0.5 0.4 0.5 0.0 0.2 0.0 2.5 0.3 0.4 0.1 0.1 6.3 7.4 10.0 7.9 5.8 16.0 28.2 17.2 14.1 13.5 22.7 15.6 0.9 3.2 3.2 70.2 4.5 9.4 5.4 2.6 3.4 0.1 1.7 1.5 1.7 0.0 2.7 1.8 0.0 2.0 8.9 0.2 0.0 0.1 1.1 0.3 8.7 0.6 0.0 0.0 36.3 2.0 0.3 16.3 7.1 0.4 0.0 12.3 1.4 0.3 1.7 0.0 39.7 1.8 10.2 1.0 20.9 3.4 18.3 2.8 5.4 80.6 1.0 14.6 5.2 339.8 3.2 1.1 0.3 11.3 0.4 5.9 0.0 0.6 2.3 0.8 0.0 6.8 3.5 2.9 5.7 1.9 11.6 1.4 2.0 10.2 0.5 6.8 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VCL ENSG00000035403 Vinculin P18206 10 73995193-74121363 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 339.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 568.3;hTERT-RPE1: 547.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002131, CAB002453, HPA063777" Enhanced Enhanced "Focal adhesion sites" NA NA 750000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites" "CAB002453: AB_564057, HPA002131: AB_1080570, HPA063777: AB_2685121" "unprognostic (8.49e-2)" "unprognostic (1.61e-2)" "unprognostic (3.14e-1)" "unprognostic (6.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.62e-3)" "unprognostic (2.72e-3)" "unprognostic (2.67e-3)" "unprognostic (3.42e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (4.03e-2)" "unprognostic (4.02e-2)" "unprognostic (1.89e-1)" "unprognostic (1.37e-3)" 85.8 19.1 9.9 52.2 10.6 41.5 45.3 8.4 11.3 73.9 33.4 180.3 35.3 167.6 45.9 92.2 75.9 69.4 132.2 10.5 11.3 37.2 24.1 68.7 18.7 10.3 10.3 45.2 40.3 51.3 13.8 88.6 13.3 131.7 73.1 12.5 31.6 151.9 136.9 37.9 52.7 224.7 9.9 41.9 63.5 41.3 12.1 12.8 39.6 144.1 23.9 135.7 56.3 8.4 147.2 97.0 174.2 123.8 213.2 246.2 95.8 188.5 568.3 126.3 141.9 88.4 124.0 6.5 153.1 331.6 86.3 183.3 115.7 95.0 132.5 12.3 49.6 69.4 92.2 37.2 116.5 14.1 101.8 205.0 25.0 171.5 154.8 547.4 171.0 11.6 50.7 14.3 213.1 25.2 2.0 16.6 82.8 69.9 342.4 24.0 90.9 18.6 180.4 185.8 6.5 25.8 104.7 117.2 53.9 152.8 54.5 21.2 230.9 136.9 57.0 67.0 179.4 2.6 6.0 28.4 160.0 38.9 39.7 15.0 13.6 36.2 14.9 17.1 10.4 5.6 7.1 7.8 20.7 2.3 2.6 5.3 11.2 4.4 19.0 8.0 1.9 28.3 9.9 10.6 8.4 11.3 10.5 11.3 10.3 10.3 13.3 9.9 12.1 8.4 68.0 99.3 39.7 56.5 13.4 114.7 161.4 68.4 30.7 13.4 39.4 58.5 339.5 37.1 79.8 42.3 85.5 51.5 46.7 91.2 3.9 60.8 5.0 98.2 152.6 60.4 38.3 5.9 63.2 61.6 78.6 74.4 66.3 149.1 35.4 45.5 56.7 34.4 23.6 16.8 47.5 44.5 22.4 31.9 51.0 7.5 50.1 77.9 26.6 55.3 44.7 9.7 61.8 18.6 4.6 125.5 48.3 76.8 8.0 100.1 13.7 14.8 37.7 34.5 105.2 49.6 179.9 18.6 13.7 45.6 93.1 39.7 18.3 44.5 48.7 94.8 VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 454.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 749.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 638.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" 99.4 107.6 56.0 38.4 60.4 55.2 87.0 60.3 73.5 111.0 64.9 97.0 44.2 109.9 87.2 51.8 90.8 58.9 99.1 57.4 59.3 122.7 454.9 77.4 35.8 64.4 59.5 115.1 168.0 51.3 115.7 45.6 63.8 76.3 41.1 23.0 92.4 69.8 34.4 81.1 82.3 84.7 59.9 62.2 88.1 55.6 68.5 35.0 76.3 32.2 32.6 100.6 88.0 64.8 73.6 187.7 57.2 165.4 638.0 389.6 68.2 269.0 229.3 128.9 218.5 79.0 83.3 54.9 141.6 331.6 87.2 66.2 79.4 103.5 139.5 81.9 204.8 52.5 239.9 378.2 103.1 104.1 74.1 225.0 54.2 173.4 146.6 336.8 141.0 78.2 70.3 130.6 253.6 271.1 74.4 205.9 106.8 98.0 175.9 132.7 160.3 286.8 127.7 61.8 119.5 146.9 118.7 84.2 137.8 91.2 138.3 123.9 126.8 171.1 61.5 159.6 101.9 76.1 80.2 50.7 445.8 174.5 90.8 77.0 127.5 196.2 118.1 94.7 116.8 91.7 116.7 119.4 127.6 102.6 102.9 101.4 104.0 84.2 98.2 157.4 143.1 112.8 56.0 60.4 60.3 73.5 57.4 59.3 64.4 59.5 63.8 59.9 68.5 64.8 95.1 57.7 51.0 5.9 30.6 84.6 68.0 157.0 10.8 12.3 93.3 117.3 20.9 141.5 64.3 108.5 8.4 85.7 48.1 34.3 62.6 204.2 6.1 25.8 83.7 89.5 67.1 32.4 8.8 129.4 293.6 132.8 10.7 48.8 55.3 60.3 118.9 749.9 184.1 10.1 7.5 44.2 46.8 80.1 94.3 13.9 158.1 66.9 115.6 5.6 107.4 68.8 51.5 6.6 17.6 103.8 28.2 172.3 29.5 59.5 152.9 204.6 33.4 19.3 59.2 78.4 99.8 30.6 34.2 10.7 112.0 39.5 39.7 82.4 49.0 55.2 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "stomach 1: 619.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 514.3;Gastric mucus-secreting cells: 623.4;Intestinal goblet cells: 285.6;Pancreatic endocrine cells: 260.2;Paneth cells: 509.9;Undifferentiated cells: 207.0;Urothelial cells: 285.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 6 "OE19: 429.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 39: Non-specific - mRNA processing" "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" 6.5 0.8 3.1 7.0 6.4 3.4 9.5 0.8 7.1 29.7 0.2 136.2 6.2 4.9 0.4 26.4 17.5 26.5 5.3 2.8 1.5 6.3 3.0 45.7 0.9 1.7 3.6 1.1 2.0 1.9 1.7 6.0 2.0 58.2 137.8 0.6 31.8 4.3 2.3 1.5 2.8 4.7 1.1 1.6 619.2 0.9 3.1 0.2 43.7 2.5 2.5 84.5 9.3 3.6 0.4 0.1 4.8 3.4 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.9 1.5 2.4 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.3 16.6 0.0 7.9 0.7 0.5 3.0 0.1 0.0 0.0 0.0 0.3 2.8 0.3 0.3 0.6 0.0 1.6 0.1 0.1 0.6 429.0 3.7 0.4 3.6 0.1 0.1 69.2 0.3 0.9 0.1 4.6 0.0 0.7 0.4 2.4 4.1 1.8 1.1 0.3 0.8 0.3 0.0 0.0 0.6 1.7 0.9 0.0 1.2 0.0 0.0 0.1 0.5 0.0 0.5 0.1 0.4 0.0 0.6 0.4 0.1 0.3 0.2 0.0 0.7 0.9 3.1 6.4 0.8 7.1 2.8 1.5 1.7 3.6 2.0 1.1 3.1 3.6 4.6 125.0 51.6 0.0 1.5 0.8 19.2 25.3 2.8 1.5 31.5 18.4 0.7 82.9 99.3 3.7 0.0 0.0 0.6 514.3 1.9 14.6 0.0 12.1 1.8 5.0 66.8 0.0 0.2 90.9 0.1 0.9 623.4 18.3 1.3 0.1 3.9 0.2 0.1 0.0 0.1 285.6 20.3 0.3 2.7 0.0 1.5 2.4 3.6 1.0 0.0 0.0 0.0 0.0 0.1 260.2 509.9 0.0 0.7 61.6 1.3 0.1 36.7 0.0 0.0 0.3 6.2 0.2 0.7 0.7 0.4 0.0 2.2 0.3 207.0 285.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 904.3;Endothelial cells: 737.5;Hepatic stellate cells: 424.4" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 56 "HUVEC TERT2: 560.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" NA NA 28300000000 5600000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" 151.9 5.9 40.0 20.2 38.8 0.8 117.3 32.9 31.4 46.0 29.2 32.7 12.8 51.1 10.6 21.9 45.7 30.2 137.8 27.4 32.3 9.7 2.1 106.2 22.8 37.6 37.4 22.0 15.0 27.3 6.3 72.7 41.7 27.4 9.2 2.9 18.1 19.2 57.0 23.5 34.5 44.2 32.2 44.1 25.7 10.8 52.4 7.0 50.8 51.6 9.5 39.7 35.5 37.1 0.0 0.0 0.0 0.0 0.7 0.6 0.5 0.0 0.6 0.2 0.4 0.0 0.3 0.0 1.2 0.0 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 560.9 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.3 0.5 0.4 0.0 0.1 10.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 40.0 38.8 32.9 31.4 27.4 32.3 37.6 37.4 41.7 32.2 52.4 37.1 904.3 12.8 25.7 3.6 1.0 6.6 0.6 1.3 4.6 0.0 4.5 4.7 112.2 1.5 1.7 11.0 0.0 1.1 2.6 0.0 0.0 0.5 6.8 2.0 1.6 737.5 0.0 2.7 2.9 0.0 0.9 21.1 0.0 2.1 5.7 0.1 424.4 3.3 0.5 0.0 2.2 0.0 4.1 5.3 3.4 15.5 5.9 2.6 5.4 75.9 0.3 0.7 0.0 1.5 4.2 0.0 0.0 0.7 0.0 1.3 0.0 0.1 1.0 1.7 0.0 12.4 34.7 2.9 5.7 4.7 4.3 1.0 2.0 10.6 0.0 1.7 WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Exocrine glandular cells: 17.2;Hofbauer cells: 21.8;Proximal tubular cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219, HPA064649, HPA070916" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB034216: AB_2234159, CAB034219: AB_2130519, HPA064649: AB_2685312, HPA070916: AB_2686322" "unprognostic (1.98e-3)" "unprognostic (3.75e-2)" "unprognostic (8.40e-2)" "unprognostic (3.89e-3)" "unprognostic (2.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (2.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.69e-2)" "unprognostic (9.10e-3)" "unprognostic (1.53e-1)" "unprognostic (9.39e-3)" "unprognostic (5.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" 18.1 18.6 10.5 18.5 16.9 21.3 19.6 14.9 13.2 17.2 16.5 18.5 18.1 16.2 15.7 16.6 13.3 17.8 16.1 11.1 12.5 22.9 18.5 17.1 19.6 14.7 13.7 15.6 13.0 24.8 9.5 21.2 14.6 17.4 20.1 11.4 14.3 16.1 15.9 13.6 14.7 20.2 14.0 19.3 16.1 9.5 13.8 21.8 23.3 18.5 21.0 21.1 10.3 24.7 40.0 45.4 24.9 30.6 55.3 58.8 16.3 42.0 63.6 43.0 45.8 17.0 42.1 36.1 29.1 54.1 25.3 30.6 40.2 37.7 56.8 47.5 23.1 48.1 26.5 22.8 53.8 14.8 46.6 58.7 25.1 35.5 31.2 33.2 49.9 30.9 28.3 35.6 53.0 87.6 44.3 11.8 23.7 66.7 46.7 29.8 22.4 36.7 33.2 48.5 13.1 26.3 48.8 109.2 39.5 25.8 47.3 25.5 44.7 23.6 51.9 39.4 37.7 31.7 31.2 31.7 62.4 27.5 33.4 10.4 17.0 12.5 13.5 20.9 14.3 9.5 12.8 13.9 19.7 10.6 10.1 14.3 5.8 17.2 29.3 7.2 16.9 13.0 10.5 16.9 14.9 13.2 11.1 12.5 14.7 13.7 14.6 14.0 13.8 24.7 10.9 3.2 19.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 14.4 9.3 0.0 0.0 5.0 11.0 0.0 13.4 6.9 0.0 5.9 12.2 0.0 9.9 13.5 4.9 0.0 0.0 0.0 17.2 11.0 5.4 0.0 14.8 8.8 11.1 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 16.2 0.0 0.0 1.9 0.0 0.0 17.2 4.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 3.8 9.6 0.0 0.0 WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 599.7" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2736.1" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.2;LHCN-M2: 1.0;NTERA-2: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" 1.3 2.7 22.4 0.3 34.3 0.0 22.9 16.3 44.6 1.6 15.0 0.3 0.0 8.6 23.8 4.7 1.5 0.0 0.5 24.8 35.4 0.7 0.0 117.4 0.1 16.6 16.5 1.2 0.3 0.0 46.5 0.0 16.2 14.2 0.3 599.7 45.1 2.8 0.1 6.6 2.2 0.9 16.5 0.1 1.4 0.7 23.4 0.2 0.0 0.7 0.0 1.7 2.2 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.4 34.3 16.3 44.6 24.8 35.4 16.6 16.5 16.2 16.5 23.4 18.4 0.0 35.3 197.8 186.1 0.0 12.6 34.5 0.0 2.2 25.0 0.7 13.7 1.6 0.0 26.6 1.8 8.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 4.7 0.0 0.0 0.6 0.0 0.0 27.8 0.5 0.1 7.6 1.0 0.0 0.0 0.0 15.2 46.5 0.0 0.0 0.0 20.4 0.0 0.0 0.8 23.2 12.2 0.0 2736.1 0.0 1.5 0.9 0.0 0.0 0.4 0.2 25.5 0.0 1.2 34.2 80.8 0.0 1.8 1.5 2.5 2.0 0.4 10.5 0.0 1.2 0.0 0.0 0.8 WIPF3 "CR16, FLJ36931" ENSG00000122574 "WAS/WASL interacting protein family member 3" A6NGB9 7 29806486-29917066 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;ovary: 41.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.1;Granulosa cells: 149.4;Leydig cells: 50.7;Peritubular cells: 100.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 22.1;cerebral cortex: 49.9;hippocampal formation: 40.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.1;HEK 293: 4.1;K-562: 6.6;NTERA-2: 5.1;RPMI-8226: 11.3;SK-MEL-30: 4.5" "Region enhanced" "Detected in all" "hippocampal formation: 213.9" "Region enhanced" "Detected in all" "hippocampal formation: 156.3" "HPA041145, HPA041211" Uncertain Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041145: AB_10795001, HPA041211: AB_10795003" "prognostic favorable (7.93e-4)" "unprognostic (1.35e-1)" "unprognostic (1.37e-3)" "unprognostic (2.12e-3)" "unprognostic (3.65e-3)" "unprognostic (1.53e-1)" "unprognostic (8.95e-3)" "unprognostic (4.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.19e-2)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (1.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.27e-2)" "unprognostic (3.33e-2)" "unprognostic (1.41e-1)" 1.0 5.6 8.7 1.0 22.1 0.5 1.1 0.0 49.9 0.4 0.0 0.7 2.9 3.3 19.7 1.2 8.8 1.4 4.0 40.3 4.2 2.5 0.5 0.5 0.7 0.4 2.6 41.7 1.7 1.2 0.9 0.2 0.1 4.4 0.5 3.8 4.0 4.8 25.0 0.9 2.6 4.1 0.5 1.0 5.9 18.8 7.4 0.4 2.0 8.8 0.7 1.4 0.2 8.1 0.3 1.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.9 0.0 0.2 0.0 18.1 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.1 0.0 0.1 0.0 0.0 5.1 0.0 3.6 0.0 0.0 11.3 0.0 0.0 1.8 1.5 0.1 0.1 4.5 2.4 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.1 0.0 8.7 22.1 0.0 49.9 40.3 4.2 0.4 2.6 0.1 0.5 7.4 8.1 1.5 0.0 0.0 6.2 0.0 2.2 1.5 0.6 1.2 8.2 4.9 4.6 9.3 0.0 1.4 3.7 2.1 0.0 0.3 0.5 3.9 3.8 1.8 5.0 0.4 4.1 1.8 3.0 45.1 3.5 0.1 7.3 11.7 1.2 0.0 149.4 0.4 0.5 4.5 5.0 27.0 0.7 0.0 0.0 1.0 4.8 50.7 1.0 5.4 1.9 0.0 6.2 0.0 2.0 1.9 2.4 1.5 100.4 0.1 1.1 5.5 5.5 5.1 2.9 6.6 7.2 16.0 4.4 9.9 0.9 0.4 0.0 1.0 8.7 2.0 0.4 WNK4 PRKWNK4 ENSG00000126562 "WNK lysine deficient protein kinase 4" Q96J92 17 42780610-42797066 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0;kidney: 37.6;prostate: 11.6" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 160.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 32.6;K-562: 36.8;TIME: 34.1;WM-115: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016500 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA016500: AB_10962984" "unprognostic (6.34e-3)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (2.48e-1)" "unprognostic (1.69e-1)" "unprognostic (5.84e-2)" "unprognostic (3.94e-1)" "unprognostic (2.08e-3)" "unprognostic (4.33e-3)" "unprognostic (7.70e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (1.43e-1)" "unprognostic (7.99e-2)" 1.3 0.0 0.7 1.1 0.9 0.0 2.8 0.8 3.3 0.6 0.3 9.8 1.9 0.2 0.7 8.9 0.4 0.0 0.1 1.7 1.1 37.6 0.2 0.1 0.1 1.1 0.7 4.3 0.2 0.0 1.2 0.0 0.7 11.6 11.0 0.6 1.8 1.1 0.0 0.5 3.7 0.4 0.6 0.1 3.4 0.2 1.0 0.0 0.0 0.3 0.1 0.2 0.4 1.0 2.1 1.2 0.6 0.0 0.7 0.2 4.8 11.9 4.8 4.5 1.3 0.7 1.0 0.6 6.8 32.6 1.2 0.0 0.2 0.3 8.6 0.6 1.8 0.1 0.0 4.7 7.4 0.3 0.7 3.9 1.4 6.4 2.1 2.1 0.3 0.4 36.8 1.3 0.0 1.0 0.0 1.1 0.3 2.0 8.2 0.6 1.2 0.0 0.0 0.5 0.0 0.2 0.1 0.2 1.7 4.1 2.4 2.7 34.1 0.3 3.1 0.5 0.4 6.2 5.3 1.2 0.0 2.1 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.8 3.3 1.7 1.1 1.1 0.7 0.7 0.6 1.0 1.0 0.2 0.0 0.6 0.0 0.5 0.0 0.2 0.0 0.6 0.2 7.1 4.1 1.0 1.5 0.6 7.3 0.0 0.0 0.3 8.0 160.4 0.0 0.0 5.1 1.1 0.2 13.1 0.0 0.2 0.2 0.2 0.1 3.1 6.7 4.5 0.1 0.7 0.0 0.0 0.0 0.2 40.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.2 0.4 0.0 3.6 0.9 1.0 2.9 0.5 0.0 0.2 0.5 0.8 0.8 12.1 0.4 0.0 0.2 0.0 13.1 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 163.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" 33.8 46.8 94.4 29.8 102.1 17.6 20.2 85.2 117.5 19.6 53.2 44.7 35.3 18.7 23.8 53.0 17.9 25.3 55.8 103.0 83.8 35.5 36.6 31.5 24.1 100.3 106.3 13.8 36.7 43.0 36.1 19.2 96.4 26.6 45.3 38.9 20.9 26.4 102.7 23.0 39.0 35.7 95.2 17.7 33.0 18.6 99.4 20.8 46.5 163.3 28.3 45.6 21.1 95.4 49.3 78.2 55.2 93.5 81.1 46.7 39.1 129.3 95.9 138.6 82.8 41.5 66.4 7.1 42.6 168.7 77.4 25.8 46.6 78.6 98.7 90.7 29.6 27.5 36.7 39.0 85.7 16.2 71.5 62.7 77.7 75.0 51.6 148.7 72.3 48.5 83.2 12.5 143.8 73.2 10.3 9.9 32.2 110.7 48.2 29.3 57.5 2.2 81.9 211.5 58.5 87.3 100.1 21.8 69.9 54.7 75.0 37.3 113.7 164.6 68.7 53.1 158.8 21.6 14.6 13.4 148.8 20.3 266.9 9.7 5.0 11.5 4.5 7.5 4.0 0.7 4.4 4.7 3.5 1.8 1.9 3.4 5.4 3.4 5.2 4.1 5.1 1.8 94.4 102.1 85.2 117.5 103.0 83.8 100.3 106.3 96.4 95.2 99.4 95.4 17.1 25.6 15.7 14.7 5.9 16.6 39.4 16.4 5.2 21.0 20.2 10.3 33.7 24.3 14.1 20.2 4.2 10.0 11.8 75.1 21.5 37.4 2.0 19.5 23.6 16.7 72.7 7.4 45.9 85.1 24.3 19.6 23.0 31.5 7.0 13.1 17.2 36.4 34.7 57.2 31.9 40.7 22.4 51.8 18.4 4.7 7.5 23.5 28.4 18.7 34.8 34.1 11.3 18.1 30.7 89.6 44.5 17.3 6.2 53.4 47.7 35.6 7.2 14.1 13.1 21.8 26.0 3.2 5.1 17.8 18.6 17.2 13.1 44.8 25.8 86.9 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 13.4" "Group enriched" "Detected in many" 10 "dendritic cells: 513.6;NK-cells: 277.1;T-cells: 240.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 423.5" "Lineage enriched" "Detected in many" 8 "NK-cells: 423.5" "Cell line enhanced" "Detected in some" "CACO-2: 3.0;RT4: 1.1;SuSa: 1.1" HPA057725 Approved "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" 1.1 0.8 0.3 3.2 0.3 14.1 0.9 0.3 0.5 1.0 0.4 1.9 3.2 3.6 0.9 0.6 1.8 1.9 0.7 0.3 0.4 0.4 5.6 3.3 5.6 0.5 0.3 0.4 0.6 0.3 0.2 1.4 0.4 0.5 1.5 0.0 1.9 1.0 0.3 0.1 2.0 1.4 0.4 13.4 2.9 0.3 0.6 3.8 0.6 0.5 3.6 2.0 0.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.4 0.1 0.4 47.2 0.2 2.7 0.3 3.6 50.1 0.3 0.1 2.1 37.1 1.9 423.5 0.3 0.1 0.0 17.1 0.3 0.3 0.3 0.5 0.3 0.4 0.5 0.3 0.4 0.4 0.6 0.4 2.9 0.0 1.1 0.0 3.3 2.4 0.0 0.0 1.8 0.0 1.6 1.4 0.8 0.0 0.0 0.0 0.0 0.1 513.6 0.3 0.0 0.1 0.0 2.4 2.0 1.0 0.0 19.2 0.0 0.0 0.0 1.1 8.2 2.2 1.3 0.0 1.4 0.6 0.4 0.0 0.0 0.7 0.0 5.0 4.0 0.0 0.0 3.7 33.8 0.0 0.8 0.0 277.1 0.0 0.0 0.0 1.1 0.0 13.2 0.0 0.0 0.2 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.9 1.1 0.0 240.6 0.0 0.1 0.1 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 ZBTB32 "FAXF, FAZF, Rog, TZFP, ZNF538" ENSG00000011590 "Zinc finger and BTB domain containing 32" Q9Y2Y4 19 35704558-35717038 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 49.0" "Cell type enhanced" "Detected in some" "B-cells: 24.0;Early spermatids: 39.6;granulocytes: 17.7;Late spermatids: 73.0;Plasma cells: 25.6;Spermatocytes: 115.5" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 5 "cerebellum: 1.4" "Immune cell enhanced" "Detected in some" "memory B-cell: 10.5" "Lineage enriched" "Detected in many" 5 "B-cells: 10.5" "Cell line enhanced" "Detected in some" "HDLM-2: 4.3;hTEC/SVTERT24-B: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA076730 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA076730: AB_2732320" "unprognostic (2.11e-3)" "unprognostic (1.08e-4)" "unprognostic (3.87e-2)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.04e-5)" "unprognostic (2.59e-1)" "unprognostic (1.76e-1)" "unprognostic (2.16e-2)" "unprognostic (1.63e-3)" "unprognostic (1.01e-2)" "unprognostic (3.78e-1)" "unprognostic (1.02e-8)" "unprognostic (2.44e-3)" "unprognostic (2.25e-1)" "unprognostic (6.26e-5)" "unprognostic (1.94e-3)" 0.1 0.1 0.2 2.0 0.1 0.6 0.0 1.4 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.3 3.4 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.1 1.7 0.1 0.0 2.6 0.5 49.0 0.1 0.3 0.1 0.0 1.3 0.5 0.0 0.1 0.7 0.6 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 2.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.3 0.0 0.0 0.4 0.1 0.3 0.0 1.2 1.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 10.5 0.5 0.6 0.0 3.8 0.1 0.3 0.0 0.0 0.0 0.0 2.3 0.6 0.2 0.1 1.4 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 1.3 0.0 24.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 39.6 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.5 0.0 17.7 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 73.0 1.2 0.3 1.8 0.0 1.6 0.0 0.0 0.0 0.2 0.0 0.0 1.2 25.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 115.5 0.8 0.0 0.0 0.0 4.1 0.0 0.1 0.0 ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018522 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.2;Proximal enterocytes: 158.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" 24.9 35.3 12.9 18.1 15.8 30.0 27.9 15.8 12.9 25.3 11.7 55.4 61.9 16.1 6.4 95.4 17.9 11.0 25.2 11.2 13.6 19.7 48.4 25.0 16.2 18.3 17.5 12.7 29.9 15.6 20.0 9.0 17.3 30.5 18.6 6.5 40.2 12.8 40.6 111.9 71.2 9.9 15.8 31.6 37.7 6.1 17.7 9.0 25.5 17.6 15.2 20.4 44.4 17.9 16.5 29.0 2.5 8.8 12.7 7.2 34.7 11.1 13.1 11.4 13.2 19.5 23.4 7.2 19.5 12.6 9.1 24.5 8.1 15.7 2.4 39.4 9.1 12.0 51.4 13.1 18.6 9.2 31.7 9.4 54.8 15.6 19.3 15.3 9.1 1.1 17.3 32.2 6.7 31.2 0.2 20.7 8.7 26.4 23.8 6.8 1.9 45.6 17.2 16.9 16.1 16.5 21.4 56.5 8.9 10.6 35.2 30.7 7.7 7.4 12.9 14.8 9.5 38.1 25.1 7.6 17.3 30.3 8.6 0.4 1.5 1.3 0.6 1.4 0.2 0.6 0.7 0.3 0.9 0.7 0.6 0.2 2.3 0.7 1.2 0.0 1.0 2.5 12.9 15.8 15.8 12.9 11.2 13.6 18.3 17.5 17.3 15.8 17.7 17.9 6.5 9.6 0.0 11.1 8.5 35.2 9.3 8.8 29.6 13.6 35.2 15.6 2.6 18.6 7.1 5.5 2.1 11.9 6.9 135.2 11.7 13.3 4.3 15.4 6.7 5.6 6.7 6.1 1.0 15.1 14.6 4.9 27.5 21.3 5.7 2.8 6.1 29.9 14.8 16.8 1.1 32.7 14.2 28.7 40.3 8.3 9.0 20.7 16.0 4.7 25.8 5.4 11.3 0.0 8.6 16.8 57.7 7.2 6.8 24.9 158.5 10.0 4.2 10.3 0.0 3.2 5.7 0.5 1.2 51.7 53.6 27.5 11.3 4.4 38.5 24.4 ZMYND19 MIZIP ENSG00000165724 "Zinc finger MYND-type containing 19" Q96E35 9 137582081-137590512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 287.8" "Group enriched" "Detected in many" 14 "Cone photoreceptor cells: 244.0;Rod photoreceptor cells: 680.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020642, HPA050761" Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA020642: AB_1859078, HPA050761: AB_2681228" "unprognostic (2.30e-2)" "unprognostic (9.62e-3)" "unprognostic (3.45e-2)" "unprognostic (7.99e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.18e-1)" "unprognostic (2.48e-1)" "unprognostic (1.35e-1)" "unprognostic (9.33e-2)" "unprognostic (1.99e-2)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (4.30e-2)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" 11.9 16.5 19.6 9.4 19.9 9.1 11.9 18.8 23.9 14.2 18.6 12.4 8.8 11.2 5.0 26.5 11.4 7.2 14.1 20.0 19.5 12.9 21.1 12.0 11.9 18.7 19.2 12.9 16.1 8.0 16.9 8.5 19.7 16.5 5.7 287.8 15.9 7.1 14.2 27.7 12.4 6.8 18.9 15.1 22.2 49.5 19.4 9.5 10.8 8.8 9.4 13.3 16.6 19.8 28.9 44.7 41.8 45.5 22.1 21.3 42.1 38.8 25.8 41.7 31.8 53.1 28.7 51.7 43.6 25.8 40.2 71.7 51.3 38.9 13.2 33.8 49.7 26.9 86.1 41.8 34.4 58.4 33.9 16.8 58.7 38.0 37.1 18.4 22.3 40.5 66.3 22.2 25.6 97.2 68.4 88.7 60.7 86.4 61.9 73.8 36.8 79.6 25.7 24.2 60.1 39.4 37.4 79.4 35.4 18.5 53.7 89.9 21.3 51.1 38.9 76.8 63.8 21.4 54.9 56.8 31.6 44.8 35.9 0.0 0.3 0.3 0.5 1.6 1.2 0.8 0.3 0.2 0.3 0.3 0.5 0.4 0.0 0.1 0.2 0.9 1.0 0.1 19.6 19.9 18.8 23.9 20.0 19.5 18.7 19.2 19.7 18.9 19.4 19.8 6.1 9.6 7.2 3.6 4.0 17.5 5.6 3.2 5.2 23.6 14.9 19.2 6.2 2.8 2.4 1.8 244.0 5.2 6.8 5.3 0.0 3.2 4.5 6.5 12.8 5.6 2.4 6.9 4.1 3.6 6.8 6.3 10.7 8.1 1.3 10.6 3.9 7.6 4.4 11.8 4.0 8.8 6.1 3.2 5.7 4.4 2.8 3.6 5.4 1.9 2.2 31.6 5.2 2.0 2.1 4.2 4.6 3.0 10.9 10.2 1.9 3.1 1.3 680.0 0.0 6.9 6.7 27.8 28.7 4.5 22.9 4.5 4.6 8.5 7.8 7.1 ZNF107 "smap-7, ZFD25, ZNF588" ENSG00000196247 "Zinc finger protein 107" Q9UII5 7 64666083-64711582 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.2" "Cell type enhanced" "Detected in many" "B-cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 47.0;REH: 49.5;U-698: 51.2" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.50e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.67e-2)" "unprognostic (2.51e-2)" "unprognostic (4.13e-3)" "unprognostic (1.62e-2)" "unprognostic (2.34e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (3.32e-1)" "unprognostic (1.66e-1)" "unprognostic (5.49e-2)" "unprognostic (7.15e-3)" 2.3 5.9 1.5 8.8 2.5 8.6 8.3 2.9 1.9 6.8 0.7 2.7 2.7 2.9 2.3 2.7 2.7 2.5 1.3 1.8 2.0 2.1 1.6 2.3 16.2 2.8 2.1 4.4 1.6 2.1 1.8 3.1 2.7 3.3 3.5 3.3 4.8 2.6 0.8 7.5 7.7 2.1 2.1 8.5 3.7 2.8 2.1 13.4 5.0 1.8 14.2 3.2 3.6 3.7 6.8 4.1 11.3 19.8 2.6 2.7 8.3 5.0 3.3 7.4 9.8 6.3 6.3 39.6 8.9 3.3 10.0 5.2 12.6 5.1 11.1 9.7 8.5 7.8 6.6 3.5 1.1 14.9 13.3 4.6 3.5 6.4 3.7 3.7 3.7 36.1 13.8 20.2 6.6 5.7 47.0 15.9 22.0 4.2 4.5 49.5 9.1 8.8 3.7 13.3 12.6 10.1 7.8 8.0 5.1 15.6 12.6 9.7 3.2 12.3 5.0 4.7 7.4 9.4 9.1 51.2 2.8 10.0 8.1 12.0 0.7 1.5 3.4 1.7 3.6 9.0 4.6 4.8 1.1 10.1 6.0 5.8 13.7 2.6 1.3 2.8 4.3 1.8 1.5 2.5 2.9 1.9 1.8 2.0 2.8 2.1 2.7 2.1 2.1 3.7 7.9 12.8 4.2 10.4 45.2 2.2 3.2 3.2 8.6 6.2 13.9 5.8 3.8 5.7 5.4 7.3 2.1 2.7 9.0 1.3 1.9 2.6 8.2 5.1 5.7 6.9 6.6 5.9 6.2 3.1 2.4 6.7 5.1 5.9 0.0 15.0 4.2 0.6 1.9 3.3 9.7 2.9 2.0 3.8 1.5 7.8 4.4 4.8 0.0 10.3 1.7 4.1 10.3 22.6 22.1 3.9 2.4 3.4 22.8 3.5 2.0 1.9 3.3 5.7 6.6 4.0 3.9 4.3 4.7 5.5 4.1 2.5 17.9 17.5 3.6 3.8 ZNF19 "KOX12, MGC51021" ENSG00000157429 "Zinc finger protein 19" P17023 16 71464555-71565089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.9;Spermatocytes: 15.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA063685 Approved Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA063685: AB_2685090" "unprognostic (5.59e-4)" "unprognostic (1.38e-1)" "unprognostic (1.39e-1)" "unprognostic (2.05e-4)" "unprognostic (6.02e-3)" "unprognostic (4.92e-2)" "unprognostic (3.34e-2)" "unprognostic (6.97e-3)" "unprognostic (2.23e-1)" "unprognostic (4.84e-2)" "unprognostic (8.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.04e-6)" "unprognostic (3.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.83e-2)" "unprognostic (4.87e-2)" 3.3 3.2 1.7 2.4 3.1 2.6 3.5 2.5 6.0 2.0 3.1 2.4 3.7 3.9 8.3 4.4 8.3 6.5 4.3 4.3 0.6 3.5 2.3 4.3 3.1 0.4 0.1 4.2 6.2 4.3 5.3 1.8 0.0 3.2 2.1 11.3 3.4 2.0 9.7 6.5 3.1 1.5 0.0 2.7 2.9 16.2 1.6 1.1 8.2 1.7 1.4 1.7 0.6 5.7 1.2 1.0 2.9 2.8 1.3 0.9 2.0 1.9 0.9 1.1 1.2 2.1 3.9 1.7 2.1 0.9 2.0 1.4 1.4 1.7 0.4 1.3 1.3 2.3 2.2 3.2 0.8 2.3 1.9 2.1 1.8 1.5 3.2 2.5 0.5 3.0 1.3 2.1 1.4 1.8 1.6 1.5 1.5 0.7 2.5 1.0 2.5 0.6 1.6 2.2 4.0 3.0 3.3 1.1 2.6 1.9 2.2 1.8 1.0 3.3 1.7 2.1 1.8 1.9 1.9 0.4 2.7 1.3 1.8 2.3 0.9 0.8 1.1 0.8 0.3 2.1 1.2 1.1 0.7 2.4 1.5 1.4 1.7 0.9 1.0 1.3 0.5 0.6 1.7 3.1 2.5 6.0 4.3 0.6 0.4 0.1 0.0 0.0 1.6 5.7 1.4 0.0 3.2 3.9 3.7 0.3 2.0 2.1 1.2 3.8 3.1 1.8 1.2 1.5 2.3 1.8 10.4 1.4 2.3 1.8 5.9 4.4 7.3 6.3 1.3 1.6 1.2 3.6 1.7 1.4 0.8 2.1 0.5 1.2 0.0 5.0 2.2 4.1 1.4 10.1 1.6 2.0 2.0 1.0 1.6 4.4 0.6 0.9 0.0 2.8 1.3 3.5 0.0 2.0 2.1 2.2 1.7 1.9 0.8 1.3 3.6 3.3 10.0 25.9 6.6 2.2 2.0 15.3 7.6 0.8 0.6 0.5 1.8 3.4 1.5 1.0 ZNF23 "KOX16, Zfp612, ZNF359, ZNF612" ENSG00000167377 "Zinc finger protein 23" P17027 16 71447597-71463095 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.0;Excitatory neurons: 10.0;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 13.0;Oligodendrocytes: 16.0;Respiratory ciliated cells: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023534 Uncertain Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA023534: AB_1859140" "unprognostic (8.49e-2)" "unprognostic (1.46e-2)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (9.89e-3)" "unprognostic (2.12e-1)" "unprognostic (8.37e-3)" "unprognostic (2.19e-2)" "unprognostic (2.62e-3)" "unprognostic (3.65e-1)" "unprognostic (6.94e-2)" "unprognostic (9.59e-2)" "unprognostic (6.04e-2)" 5.5 4.3 8.6 5.3 8.4 4.4 6.2 8.8 9.9 5.8 8.9 5.6 2.8 6.9 8.0 4.2 7.1 3.6 5.1 8.6 8.5 5.6 5.4 5.4 6.2 8.4 8.3 8.2 4.6 5.4 14.3 4.7 8.1 5.3 5.7 16.9 4.3 5.8 6.5 5.8 5.0 6.9 8.2 5.7 4.1 6.9 8.6 4.9 7.5 7.1 6.0 4.2 3.5 9.8 7.8 4.7 12.0 8.8 7.6 6.6 7.8 17.1 15.9 11.7 8.6 6.1 7.6 15.1 4.2 13.1 11.4 4.7 7.9 10.2 13.7 4.0 5.2 6.7 5.0 6.5 9.2 12.3 5.7 10.7 9.0 12.1 18.6 10.9 4.1 7.9 11.1 2.9 12.5 13.0 6.4 6.0 13.4 4.0 3.9 3.3 5.3 4.6 7.7 6.4 9.9 12.8 5.5 3.9 5.3 7.5 5.1 6.4 11.5 21.2 7.2 5.9 10.7 6.5 10.6 19.8 16.0 6.2 13.2 0.8 0.8 0.5 1.9 1.8 1.8 1.3 1.0 2.1 1.1 2.7 2.1 1.5 0.0 2.6 1.0 1.9 1.9 0.9 8.6 8.4 8.8 9.9 8.6 8.5 8.4 8.3 8.1 8.2 8.6 9.8 0.6 6.4 2.3 15.0 2.6 0.3 0.3 0.2 2.8 2.6 0.7 0.6 0.4 0.0 3.2 0.0 6.2 0.2 0.4 0.5 1.9 2.0 0.2 1.0 1.0 1.1 0.0 7.8 10.0 1.0 0.3 0.9 1.5 0.5 2.5 1.3 1.1 0.5 0.4 3.3 11.2 1.0 0.0 0.3 0.3 0.0 0.6 0.5 0.0 6.5 0.4 1.4 2.1 13.0 16.0 1.5 1.4 0.0 1.5 0.3 0.7 0.3 9.2 3.3 0.0 0.7 0.9 1.5 1.4 2.3 0.0 0.0 1.4 0.5 1.5 0.1 ZNF385D "FLJ22419, ZNF659" ENSG00000151789 "Zinc finger protein 385D" Q9H6B1 3 21412218-22373321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 44.0;testis: 15.1" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 1766.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 8 "cerebellum: 44.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.8;hTERT-RPE1: 5.4;LHCN-M2: 5.3;PC-3: 5.3;RPTEC TERT1: 15.1;U-87 MG: 21.1" "Low region specificity" "Detected in all" HPA036190 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA036190: AB_10602355" "unprognostic (4.07e-2)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (3.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.74e-1)" "unprognostic (8.20e-2)" "unprognostic (6.60e-2)" "unprognostic (7.84e-2)" "unprognostic (3.73e-1)" "unprognostic (2.35e-1)" "unprognostic (9.01e-2)" "unprognostic (3.49e-7)" "unprognostic (8.70e-3)" "unprognostic (5.38e-2)" "unprognostic (7.76e-3)" "unprognostic (2.15e-5)" 3.8 0.2 2.6 1.4 4.5 0.3 2.2 44.0 5.4 1.8 0.0 0.8 0.3 1.1 0.5 2.0 0.7 2.7 1.8 1.7 2.5 1.4 0.1 0.6 0.8 3.3 4.5 0.6 0.6 0.2 0.1 0.0 3.6 1.3 0.5 7.3 0.7 1.1 1.0 0.7 0.5 1.7 1.5 0.3 0.4 15.1 3.1 0.7 0.5 3.3 1.0 2.7 1.2 5.3 0.0 0.0 0.3 0.0 2.0 4.3 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.2 0.0 5.4 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 5.3 0.0 0.0 0.0 15.1 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.1 0.0 0.0 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 2.6 4.5 44.0 5.4 1.7 2.5 3.3 4.5 3.6 1.5 3.1 5.3 82.2 12.8 13.4 17.3 1.4 9.7 0.7 6.2 1.8 58.8 1.5 6.3 3.6 1.5 19.2 1.8 8.4 0.3 1.4 0.9 27.4 0.6 174.9 0.2 1.9 89.0 0.0 12.6 267.5 0.7 0.2 20.5 0.0 0.3 5.1 1.8 2.2 5.8 0.4 323.0 1766.6 0.7 0.0 0.0 14.0 274.5 16.8 4.9 12.4 64.6 0.6 114.3 1.0 159.3 12.7 1.4 0.6 13.5 0.3 1.7 2.3 6.6 4.4 31.0 13.1 22.0 20.2 50.4 2.0 0.6 7.7 0.1 1.5 34.3 0.7 1.0 ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 255.0;Squamous epithelial cells: 189.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 115.1;PC-3: 149.2;U-87 MG: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" 14.5 39.9 6.1 3.1 10.1 2.0 9.2 3.8 5.2 34.5 1.0 17.7 8.1 44.1 10.3 20.1 23.8 2.4 9.0 7.4 5.5 25.6 7.1 14.2 1.5 12.0 9.2 46.3 25.4 4.6 4.8 3.3 7.6 17.5 1.8 1.4 9.5 17.6 3.6 5.3 8.5 7.7 10.0 8.0 16.3 2.4 8.1 1.1 7.8 2.1 1.0 13.8 18.2 6.5 5.2 4.9 1.1 6.3 10.6 7.1 1.6 4.6 2.8 1.9 1.7 7.5 20.4 0.0 13.4 4.6 1.1 9.4 0.7 4.9 1.4 0.0 115.1 0.0 12.4 24.8 8.5 6.1 12.9 19.1 4.8 3.5 2.0 16.6 0.5 0.5 0.1 0.2 2.6 2.7 0.2 18.8 0.1 3.8 149.2 0.0 5.6 0.1 2.8 4.1 4.1 5.2 8.5 0.6 27.1 1.0 1.0 4.2 3.9 14.6 16.3 30.7 13.0 0.0 0.0 0.0 44.9 27.2 11.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.1 3.8 5.2 7.4 5.5 12.0 9.2 7.6 10.0 8.1 6.5 27.2 38.5 11.6 2.3 1.7 27.1 35.6 15.0 255.0 23.7 7.7 42.3 20.4 10.0 10.1 40.5 20.9 0.5 2.1 0.8 58.7 45.9 0.1 53.2 72.2 41.0 3.6 5.3 12.6 34.7 0.3 60.1 18.3 48.1 6.3 2.7 44.6 10.3 13.5 6.7 3.2 6.7 10.2 27.4 30.5 2.0 59.7 30.7 24.9 13.1 8.2 7.7 0.0 4.0 0.7 33.2 1.5 49.2 3.9 19.7 13.4 32.5 1.7 26.3 39.5 10.2 78.1 0.2 6.0 189.3 13.9 0.3 4.0 24.5 9.7 14.3 ZNF552 FLJ21603 ENSG00000178935 "Zinc finger protein 552" Q9H707 19 57803841-57814913 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 23.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 25.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.3" "Cell line enhanced" "Detected in all" "BEWO: 30.3;RT4: 42.5;T-47d: 69.6" "Low region specificity" "Detected in all" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA043800: AB_2678675, HPA053762: AB_2682252, HPA072145: " "prognostic favorable (4.57e-4)" "unprognostic (2.09e-1)" "prognostic favorable (2.66e-4)" "unprognostic (9.03e-2)" "unprognostic (9.89e-2)" "prognostic favorable (9.96e-4)" "unprognostic (3.03e-2)" "unprognostic (1.29e-3)" "unprognostic (3.36e-3)" "unprognostic (6.72e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-1)" "unprognostic (2.24e-3)" "unprognostic (2.41e-2)" "unprognostic (9.01e-2)" "unprognostic (3.09e-1)" "unprognostic (2.04e-3)" 3.0 2.3 3.0 4.7 3.1 8.1 26.0 14.9 6.5 9.8 9.3 9.4 7.1 5.0 5.4 5.5 5.6 8.7 2.9 3.4 3.0 7.1 4.7 6.0 5.3 2.8 2.0 4.2 4.2 6.0 2.5 6.5 2.3 12.4 12.1 4.0 17.5 6.9 4.9 9.7 7.3 3.0 0.5 6.0 13.9 3.0 3.5 5.0 4.1 2.7 5.5 14.7 5.8 3.4 5.6 3.2 3.7 5.9 3.0 1.5 30.3 2.0 2.4 4.5 2.5 9.6 8.8 7.6 3.8 3.6 1.0 4.8 7.6 5.0 5.4 3.4 15.1 2.6 8.4 7.1 7.1 8.5 3.4 3.3 10.9 3.1 3.2 2.8 6.0 8.0 5.5 2.5 3.0 5.0 3.7 2.5 5.2 6.9 7.3 7.6 4.7 8.0 13.4 42.5 4.9 3.5 10.2 22.6 5.1 10.4 69.6 3.5 4.5 3.8 4.2 2.5 3.5 11.0 8.1 6.1 3.1 6.4 2.2 2.1 3.3 7.4 2.7 3.3 2.5 3.7 3.4 4.3 1.7 3.7 4.5 3.8 25.3 2.4 1.4 2.3 3.0 2.4 3.0 3.1 14.9 6.5 3.4 3.0 2.8 2.0 2.3 0.5 3.5 3.4 2.9 12.8 3.1 4.2 7.8 2.5 14.8 9.7 8.0 6.2 19.4 9.8 3.1 18.6 15.0 20.2 2.1 22.1 5.3 9.4 25.4 6.9 5.7 20.2 4.9 3.7 8.4 6.1 7.7 1.8 5.2 3.8 19.4 15.0 8.8 14.2 7.1 4.2 5.2 3.3 8.1 14.5 14.2 2.4 3.1 1.5 2.8 3.6 1.8 1.9 3.1 2.3 2.1 4.5 5.1 3.1 13.4 2.2 4.8 8.3 15.6 4.8 20.5 12.7 6.6 2.9 3.5 3.8 4.6 7.0 2.7 21.3 7.1 5.4 9.3 14.2 ZNF652 KIAA0924 ENSG00000198740 "Zinc finger protein 652" Q9Y2D9 17 49289206-49362473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044408 Uncertain Approved Nucleoplasm No No "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA044408: AB_2678932" "unprognostic (1.33e-2)" "unprognostic (5.54e-2)" "unprognostic (1.15e-1)" "prognostic favorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (7.31e-3)" "unprognostic (2.34e-1)" "unprognostic (4.52e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-1)" "unprognostic (4.09e-3)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.30e-2)" 2.1 2.3 4.6 2.8 11.4 3.7 9.6 6.7 4.7 3.2 1.5 2.8 2.6 2.1 2.0 2.0 2.1 2.2 1.6 3.6 6.2 2.5 4.0 2.8 2.9 10.7 8.2 2.8 2.4 3.6 1.0 2.6 11.4 3.3 2.9 4.5 4.4 2.4 10.5 6.6 2.1 2.7 5.2 4.6 3.4 3.7 7.9 3.4 3.6 2.5 3.0 2.1 1.1 18.0 4.3 2.9 3.2 4.1 4.3 2.3 4.3 1.6 2.6 1.8 2.1 6.8 2.7 9.7 5.0 3.3 1.4 3.0 2.9 3.1 2.9 3.3 2.6 3.5 5.0 4.7 1.6 2.9 5.3 3.2 2.8 1.6 2.9 1.8 2.2 4.8 2.7 8.1 1.8 6.0 4.3 1.6 3.2 2.5 2.1 3.4 6.6 4.6 2.4 5.7 5.9 4.0 2.8 3.9 4.2 4.8 7.1 4.1 3.6 5.9 4.4 2.6 2.6 10.3 7.6 6.3 3.2 2.6 2.2 7.7 3.0 3.2 2.6 2.6 3.5 1.9 1.9 2.0 2.1 2.6 1.8 1.9 5.9 2.1 3.4 1.9 0.9 2.5 4.6 11.4 6.7 4.7 3.6 6.2 10.7 8.2 11.4 5.2 7.9 18.0 28.8 19.2 19.8 37.5 38.6 16.4 14.2 7.8 18.8 56.5 63.7 50.2 16.6 21.5 15.2 29.5 64.6 24.0 60.6 22.7 13.7 18.6 19.2 56.6 45.1 24.3 12.1 22.3 49.2 19.6 18.2 24.4 16.8 59.1 5.1 24.0 29.6 41.6 12.8 43.7 70.9 20.4 14.2 41.6 32.4 17.3 48.4 25.1 26.6 65.6 37.0 30.1 45.3 76.9 152.6 18.4 18.5 44.4 21.9 24.6 17.9 12.4 21.3 47.1 0.0 30.0 22.8 60.4 29.9 15.6 24.3 13.4 33.7 27.7 24.0 12.6 ZNF683 "Hobit, MGC33414" ENSG00000176083 "Zinc finger protein 683" Q8IZ20 1 26361634-26374522 "Predicted intracellular proteins, Transcription factors" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 81.9" "Group enriched" "Detected in some" 12 "Early spermatids: 473.7;Late spermatids: 482.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "gdT-cell: 172.4;memory CD8 T-cell: 113.1" "Lineage enriched" "Detected in many" 15 "T-cells: 172.4" "Group enriched" "Detected in some" 8 "NB-4: 2.2;OE19: 4.8" "Not detected" "Not detected" HPA023865 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA023865: AB_2671333" "unprognostic (3.95e-3)" "unprognostic (5.58e-3)" "unprognostic (5.83e-2)" "prognostic favorable (2.90e-5)" "unprognostic (9.17e-2)" "unprognostic (8.98e-4)" "unprognostic (7.90e-2)" "unprognostic (5.05e-3)" "unprognostic (5.81e-3)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.30e-2)" "unprognostic (3.54e-8)" "unprognostic (5.90e-3)" "unprognostic (1.63e-1)" "unprognostic (1.14e-2)" "prognostic favorable (3.45e-5)" 0.2 0.4 0.3 0.6 0.6 1.9 0.8 0.3 0.3 0.9 0.1 0.3 0.3 0.6 0.1 0.7 1.7 1.7 0.8 0.8 0.3 0.3 0.6 4.7 1.9 1.1 0.3 1.0 0.3 0.2 0.3 0.4 0.5 0.9 0.5 0.0 10.1 0.8 0.1 0.5 0.6 0.3 0.5 2.2 3.4 81.9 0.5 2.9 1.1 0.0 0.4 0.9 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.2 0.1 172.4 0.1 0.4 0.2 35.4 113.1 0.0 0.0 13.4 63.2 0.9 11.8 3.8 0.3 1.1 24.2 0.3 0.6 0.3 0.3 0.8 0.3 1.1 0.3 0.5 0.5 0.5 0.6 0.9 3.2 0.6 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.7 1.1 0.2 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 0.0 473.7 0.2 0.5 0.8 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.4 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 482.4 1.8 1.8 0.0 0.0 0.3 0.0 6.2 0.0 0.1 0.0 0.0 1.2 1.7 0.1 0.0 0.2 0.7 0.0 0.0 0.4 0.7 3.3 2.2 0.2 0.0 0.0 39.8 0.0 0.0 0.0 ZNF80 pT17 ENSG00000174255 "Zinc finger protein 80" P51504 3 114234631-114237578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 3.1" "Cell type enhanced" "Detected in some" "dendritic cells: 3.2;granulocytes: 1.3;NK-cells: 2.1;Plasma cells: 1.4;T-cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Not detected" "Not detected" HPA065484 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA065484: AB_2685496" "unprognostic (6.27e-3)" "unprognostic (3.00e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.52e-2)" "unprognostic (9.68e-5)" "unprognostic (5.36e-1)" "unprognostic (6.52e-3)" "unprognostic (2.80e-2)" "unprognostic (1.27e-2)" "unprognostic (6.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.69e-12)" "unprognostic (1.85e-1)" "unprognostic (3.10e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-2)" 0.1 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 3.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 1.3 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.7 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.7 0.0 0.4 0.0 5.2 0.1 0.1 0.0 ZNF92 "HPF12, TF12" ENSG00000146757 "Zinc finger protein 92" Q03936 7 65373799-65401136 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003173 Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA003173: AB_1080744" "unprognostic (1.07e-1)" "unprognostic (1.36e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "unprognostic (8.53e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (5.48e-3)" "unprognostic (1.30e-2)" "unprognostic (3.86e-2)" "unprognostic (5.83e-2)" "unprognostic (1.40e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-3)" 2.7 4.5 2.9 5.5 3.5 16.5 10.4 5.8 4.9 5.1 1.4 4.1 4.0 3.5 4.5 5.5 3.3 4.0 2.9 2.8 3.4 3.5 3.2 3.2 10.9 3.6 3.5 5.5 3.6 4.9 2.0 3.7 3.8 3.6 4.5 3.0 2.7 3.3 2.7 3.1 4.5 2.4 4.2 6.7 5.1 5.2 3.5 10.2 6.0 4.2 9.6 3.8 2.4 4.9 7.6 5.0 21.7 21.6 5.4 6.6 10.4 6.1 4.6 6.6 9.6 9.3 10.9 29.3 11.6 3.4 10.0 7.3 17.2 4.2 10.7 11.1 11.4 13.1 2.7 9.3 2.0 16.2 12.1 5.6 3.6 6.1 4.7 8.9 8.3 15.4 17.3 11.7 9.7 2.2 23.7 17.6 29.3 7.9 6.9 21.3 12.8 9.9 7.3 15.1 18.5 14.0 9.4 14.6 7.0 20.7 10.3 21.5 6.1 7.7 6.9 4.6 8.8 7.4 6.9 41.8 5.1 12.6 6.9 4.7 1.3 3.5 2.1 1.8 4.4 8.5 3.2 3.2 1.9 7.1 3.8 4.1 1.1 7.7 2.5 1.9 5.0 1.7 2.9 3.5 5.8 4.9 2.8 3.4 3.6 3.5 3.8 4.2 3.5 4.9 13.9 9.6 1.1 3.9 44.9 5.6 7.2 3.1 8.6 8.2 15.9 11.6 5.2 5.7 6.2 5.5 0.0 6.5 35.4 4.6 11.7 7.9 1.3 5.8 11.2 9.3 7.2 13.5 7.7 4.7 5.4 9.6 6.6 11.9 11.4 17.0 9.3 2.2 4.5 5.0 11.1 8.2 6.1 6.3 3.8 2.2 7.2 11.7 5.4 3.7 10.8 11.8 14.4 12.1 12.3 6.4 7.4 6.4 17.6 6.7 2.4 5.0 2.1 5.0 0.0 11.1 10.2 25.1 24.8 5.1 3.8 4.9 23.2 16.4 6.2 7.1 ZSCAN1 "FLJ33779, ZNF915" ENSG00000152467 "Zinc finger and SCAN domain containing 1" Q8NBB4 19 58034025-58054631 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.8;pituitary gland: 15.9;testis: 8.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 11.7;Early spermatids: 28.2;Endometrial ciliated cells: 21.8;Late spermatids: 19.6;Spermatocytes: 13.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.0;HMC-1: 2.1;NTERA-2: 2.1;T-47d: 3.1" HPA007938 Uncertain Approved Nucleoli NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoli "HPA007938: AB_1080768" "unprognostic (1.60e-3)" "unprognostic (2.44e-1)" "unprognostic (2.21e-1)" "unprognostic (3.58e-1)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (1.97e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-1)" "prognostic favorable (7.36e-4)" "unprognostic (1.41e-2)" "unprognostic (3.81e-2)" "unprognostic (1.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.32e-1)" "unprognostic (2.47e-2)" "unprognostic (3.60e-1)" 0.1 0.9 3.7 0.0 2.7 0.1 0.9 4.1 4.6 1.2 1.4 0.3 0.0 0.6 6.1 0.1 2.1 0.2 0.5 3.6 7.8 2.6 0.1 0.5 0.0 4.0 5.3 0.6 1.0 2.6 15.9 0.2 3.1 2.4 0.0 2.3 0.4 0.8 0.0 0.2 0.1 0.1 2.1 0.2 0.1 8.7 5.1 0.6 5.9 0.0 0.0 0.5 0.3 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.6 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 2.7 4.1 4.6 3.6 7.8 4.0 5.3 3.1 2.1 5.1 1.6 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.2 0.0 3.4 1.8 2.2 1.1 1.5 0.2 1.8 2.1 0.0 0.0 0.0 11.7 1.7 28.2 21.8 3.1 0.5 0.0 0.0 3.8 0.0 0.0 0.8 0.0 1.7 0.0 3.2 0.4 0.0 0.1 3.3 5.4 0.0 0.0 0.0 0.0 19.6 0.9 0.1 1.8 2.8 0.0 8.1 0.0 4.0 1.8 0.3 0.0 0.0 0.0 0.9 0.0 0.2 4.3 2.6 0.0 0.0 0.6 13.7 2.7 0.0 0.0 0.0 0.1 6.7 0.0 0.5 ZSCAN16 "dJ265C24.3, FLJ22191, ZNF392, ZNF435" ENSG00000196812 "Zinc finger and SCAN domain containing 16" Q9H4T2 6 28124609-28130082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 69.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007290 Supported Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA007290: AB_1080721" "unprognostic (1.50e-1)" "prognostic favorable (5.73e-4)" "unprognostic (3.29e-2)" "unprognostic (8.93e-2)" "unprognostic (3.05e-3)" "unprognostic (1.00e-2)" "unprognostic (3.07e-2)" "prognostic favorable (3.19e-4)" "unprognostic (1.23e-2)" "prognostic favorable (1.14e-5)" "unprognostic (2.50e-1)" "unprognostic (1.98e-1)" "unprognostic (2.50e-1)" "unprognostic (1.55e-2)" "unprognostic (2.14e-1)" "unprognostic (3.37e-3)" "prognostic favorable (3.41e-5)" 3.2 3.9 5.3 5.5 6.4 3.2 7.0 7.7 7.6 3.9 5.2 7.1 8.6 3.9 7.1 3.6 4.1 4.0 3.0 5.6 6.6 5.4 4.4 4.9 8.3 6.4 5.9 2.5 4.9 6.9 3.2 2.2 6.4 4.7 9.0 7.2 6.6 5.8 3.2 6.9 8.4 4.7 5.5 7.4 7.0 2.2 6.1 8.0 4.6 2.7 9.1 4.2 2.7 9.1 0.1 8.8 11.1 8.2 3.0 0.7 9.1 3.0 6.4 7.8 8.4 6.1 5.7 8.8 8.0 2.8 5.4 6.8 7.8 4.4 7.4 12.8 10.8 9.1 7.4 8.7 4.8 6.8 7.4 1.0 7.3 6.6 3.6 8.3 14.7 0.2 1.3 7.3 2.1 10.0 0.0 10.7 2.3 7.4 5.3 10.9 8.4 12.2 9.3 12.6 15.0 16.5 1.5 9.2 10.9 7.2 12.2 3.2 4.6 2.9 6.7 4.4 7.9 3.7 12.5 2.4 1.3 3.4 1.6 69.0 8.6 10.2 13.8 11.8 17.7 19.3 12.0 10.6 9.0 14.6 14.5 11.8 15.6 17.7 11.6 19.6 14.7 8.6 5.3 6.4 7.7 7.6 5.6 6.6 6.4 5.9 6.4 5.5 6.1 9.1 5.6 6.4 2.6 0.3 5.6 1.8 0.8 4.9 1.2 3.8 5.2 5.6 1.6 10.0 7.5 7.3 4.2 2.2 12.6 4.7 5.9 12.8 3.3 4.2 0.8 4.0 1.8 8.2 1.4 12.6 1.2 1.4 4.6 3.3 2.5 4.8 4.2 2.0 2.1 1.7 1.1 6.0 14.2 3.8 1.3 1.5 0.6 4.3 1.8 1.0 6.1 5.6 11.3 3.5 3.7 9.6 6.1 3.4 4.2 1.3 10.3 8.3 7.7 6.6 0.0 1.7 3.7 1.7 6.3 2.7 1.3 1.8 6.1 2.2 7.0 1.1